News May 15, 2026 Prioritizing personalized care and minimally invasive options for fibroid treatment Uterine fibroid management at Mayo Clinic emphasizes individualized care through comprehensive imaging, multidisciplinary collaboration and prioritizing minimally invasive options. May 15, 2026 Urgent fetal intervention required for twin-twin transfusion syndrome Twin-twin transfusion syndrome (TTTS) is a rare yet serious complication of monochorionic twins requiring urgent fetal intervention. Mayo Clinic is one of the few medical centers offering treatment of TTTS worldwide. May 15, 2026 Diagnostic criteria, imaging protocols and treatment options for uterine isthmocele C-section scar defects are becoming a more commonly recognized cause of abnormal uterine bleeding and secondary unexplained infertility. A recent Mayo Clinic study analyzed the clinical presentation, diagnosis and manag[...] Sept. 26, 2025 Optimizing the outcome of prenatal myelomeningocele repair Mayo Clinic specialists in Pediatric Neurosurgery and Maternal and Fetal Medicine perform this challenging procedure. The neurological effects are usually reversed, and the average gestational age at birth is 34.2 weeks[...] Aug. 21, 2025 Stage 3C endometrial cancer: Molecular classification alone is insufficient for prognosis Mayo Clinic researchers wondered if molecular classification would account for recurrence-free survival variability in patients with endometrial cancer. Study findings published in the International Journal of Gynecolog[...] Aug. 21, 2025 Cervical cancer: Perinatal care offers an ideal time for screening For pregnant patients, cervical cancer risk can be glossed over and delay diagnosis — contributing to 40% of patients who are diagnosed without prior screening. Pregnancy offers a unique opportunity where screenin[...] Aug. 21, 2025 Pelvic endometriosis: Ultrasound or MRI? Imaging holds potential for both diagnosis and treatment planning for pelvic endometriosis. Mayo Clinic researchers conducted a review study to determine whether one of these radiologic modalities was superior, and the [...] May 17, 2025 Mayo Clinic undertakes unique curative-intent surgery for select recurrent gynecologic cancers Gynecologic Oncology at Mayo Clinic in Minnesota performs lifesaving, curative-intent surgery to treat select patients' recurrent yet localized nonmetastatic gynecologic cancers. March 18, 2025 Contemporary considerations for hypertensive disorders of pregnancy Early determination of patients with hypertensive disorders of pregnancy (HDP) is critical to be able to monitor these pregnancies and schedule delivery at the optimal time for the mother and unborn child. March 18, 2025 Q&A: Opioid alternatives following pelvic reconstructive surgery A Mayo Clinic urogynecologist studied an opioid-sparing, multimodal protocol compared with usual care following pelvic reconstructive. In this Q&A, she explains the findings, patient and physician impacts, and excep[...] March 18, 2025 Mayo Clinic authors deem maternal health factor risk adjustment imperative for perinatal care quality ratings Mayo Clinic investigators found that risk adjustment for maternal age, diabetes and hypertensive disorders is feasible and significantly affects a hospital's perinatal care ratings from The Joint Commission. Feb. 28, 2025 Fast-track endometrial cancer care at Mayo Clinic Mayo Clinic Gynecologic Oncology targets a 2- to 3-week time frame for people at high risk to undergo biopsy, receive pathology results and have surgery if needed. Jan. 22, 2025 Artificial intelligence (AI)-enabled digital stethoscope can help diagnose peripartum cardiomyopathy Mayo Clinic Cardiovascular Medicine researchers found that an artificial intelligence (AI)-enabled digital stethoscope can help diagnose pregnancy-related heart failure. The study was published in Nature Medicine. Nov. 12, 2024 Defining successful SUI treatment: A look at patient perceptions of success A study published in the American Journal of Obstetrics and Gynecology found that patients' expectations for stress urinary incontinence (SUI) success were lower than the stringent medical definition of success. Nov. 12, 2024 Asherman syndrome: A rare collection of symptoms that can profoundly affect patients A Mayo Clinic investigator is researching causes of Asherman syndrome and seeks to determine a standardized classification system. He also is pursuing multicenter research on treatment outcomes, especially regarding pos[...] Nov. 12, 2024 Are isolated tumor cells significant for prognosis? Isolated tumor cells (ITCs), tiny malignant cells in the sentinel lymph nodes, can arise in patients with low-risk endometrial cancer. A Mayo Clinic gynecologic oncologist addresses research questions about prognosis an[...] Nov. 12, 2024 Multisite study finds FETO associated with reduced postbirth ECMO for fetuses with CDH A multisite study found a potential morbidity reduction — lowered need for extracorporeal membrane oxygenation (ECMO) — in a subpopulation of infants with severe, left-sided congenital diaphragmatic hernia t[...] July 27, 2024 Modified Mohs surgery reduces recurrence of extramammary Paget's disease A Mayo Clinic study found that a multidisciplinary surgical approach using modified Mohs surgery lowered recurrence for patients with female EMPD compared with traditional WLE. July 27, 2024 Mayo Clinic investigators discover new clues to early ovarian cancer detection and treatment response prediction A study published in Scientific Reports describes the finding of a distinct ovarian cancer microbiome. This discovery may benefit earlier disease diagnosis and prediction of treatment effectiveness. July 27, 2024 Increased risk of cardiovascular disease associated with tubal ligation, hysterectomy alone or hysterectomy with oophorectomy A multicenter study indicated that hysterectomy — alone or combined with oophorectomy — and tubal ligation may increase cardiovascular disease risk. The Journal of Women's Health published these findings. July 27, 2024 Mayo Clinic investigators discover a surprisingly high number of women have experienced premature or early menopause Mayo Clinic investigators were surprised to find higher numbers of premature menopause and early menopause than they anticipated. July 27, 2024 Discovery of a healthy embryo clue will improve selection for in vitro fertilization transfer Investigators at Mayo Clinic have found patterns to identify the best embryos for IVF. Reproductive Sciences published the paper about the findings. May 30, 2024 Advancing care for childbirth-related pelvic floor disorders Nikki J. Ron, P.T., D.P.T., WCS-ABPTS, explains the evolving role of Mayo Clinic physical therapists in pregnancy and postpartum care. April 10, 2024 Mayo Clinic pilot study pinpoints resectable high-grade serous ovarian cancer A pilot study assessing CT plus molecular subtyping provided useful information for patients and surgeons indicating which patients have low likelihood of successful disease resection. April 10, 2024 Mayo Clinic investigators surprised: Fetal surgery not associated with increased placental pathologies Findings published by Mayo Clinic investigators in Prenatal Diagnosis indicate that fetal surgery does not elevate abnormal findings in placental pathology assessment, contradicting the researchers' first hypothesis yet[...] April 10, 2024 Ovarian tissue vitrification potentially demonstrates superiority over slow freezing A Mayo Clinic research team found some superiority in ovarian tissue vitrification versus slow freezing due to stromal cell viability. The researchers call for a multicenter study to confirm these findings. April 10, 2024 Management of deep bowel endometriosis Patients with bowel endometriosis spend on average six years with symptoms before diagnosis. Detection and surgical excision of this disease are challenging, yet Mayo Clinic GYN surgeons take it on. Jan. 09, 2024 OB-GYN hospitalists associated with lower severe maternal morbidity A multicenter study led by a Mayo Clinic physician and published in the Journal of Patient Safety indicated lower severe maternal morbidity rates in medical centers using OB-GYN hospitalists. Jan. 09, 2024 A substantial step toward earlier endometrial cancer detection A Mayo Clinic study discovers methylated DNA markers present in malignant endometrium and not present in benign tissue using vaginal fluid self-collected with an over-the-counter tampon. Jan. 09, 2024 Mayo Clinic investigates persistent pelvic pain following endometriosis surgery Despite surgery for bothersome endometriosis, some women continue to experience debilitating pain. A Mayo Clinic minimally invasive gynecologic surgeon delves into the problem and potential solutions. Jan. 09, 2024 Minimally invasive versus open abdominal sacrocolpopexy Q&A A Q&A provides a Mayo Clinic urogynecologic surgeon's responses regarding two sacrocolpopexy techniques. He and a colleague published an invited commentary in Journal of Gynecologic Surgery. Jan. 09, 2024 Mayo Clinic GYN surgeon urges consideration of nonsurgical options for symptomatic uterine fibroids Contrary to what might be expected, a Mayo Clinic GYN surgeon is urging healthcare professionals to consider not only hysterectomy but also nonsurgical options for patients with symptomatic uterine fibroids. July 11, 2023 Hypothesis disproved on uterine fibroids and elevated nerve activity, other fibroid relationships uncovered Contrary to their hypothesis, investigators did not find high nerve activity in women with uterine fibroids. They did find vascular distinctions between those with and without fibroids. July 11, 2023 Study finds outcomes comparable between minimally invasive and open surgery for patients with high-risk endometrial cancer Due to equivalent surgical and oncologic outcomes of minimally invasive surgery compared with open surgery for high-risk endometrial cancer, investigators recommend minimally invasive surgery. May 13, 2023 New customizable mold created for vaginoplasty postoperative period Mayo Clinic Urogynecology and Radiology anatomic modeling experts collaborated to create a 3D-printed, anatomically customizable, temporary vaginal mold from dental resin for use after neovagina creation. May 13, 2023 A promising abdominal wall endometriosis treatment emerges at Mayo Clinic through teamwork A multidisciplinary research team at Mayo Clinic found that cryoablation has multiple advantages for patients with abdominal wall endometriosis compared with surgery. May 13, 2023 Challenging search for ovarian cancer early detection assay appears hopeful In a clinical pilot study, an 11-MDM ovarian cancer panel, developed at Mayo Clinic, distinguished cancer and noncancer in plasma and identified all five early-stage, high-grade serous ovarian cancers included. Jan. 13, 2023 Mayo Clinic and Universite de Montreal scientists discover distinct inflammatory profiles between preterm and term births Mayo Clinic and Universite de Montreal scientists found new genes and inflammatory biological processes abnormally expressed at the maternal-fetal interface in preterm births. Jan. 13, 2023 Quantifying status of labor progression through machine learning Mayo Clinic investigators published a paper in a 2022 issue of PLOS ONE detailing how they use machine learning to quantify whether a patient's labor is progressing well or needs intervention. Jan. 13, 2023 Q&A: Mayo Clinic in Minnesota adds autotransplantation to ovarian tissue cryopreservation services Building on a history of pediatric ovarian tissue cryopreservation, Mayo Clinic has broadened this service to include more adults. Now, Mayo Clinic also offers ovarian tissue autotransplant. Sept. 30, 2022 Fertility unaffected by myomectomy route Investigators found that patients treated using any of three myomectomy routes had similar fertility postsurgically, allowing surgeons and their patients to select any route appropriate for the patient. Sept. 30, 2022 Hysterectomy for endometrial cancer shifts significantly toward outpatient approach Hysterectomy for endometrial cancer has shifted from the inpatient setting to minimally invasive surgery in the outpatient setting according to a study published in International Journal of Gynecological Cancer. Sept. 30, 2022 Pessary use and surgery improve prolapse symptoms, yet patients favor surgical outcomes A self-controlled, prospective Mayo Clinic study found that participants who trialed pessaries before surgery found that both therapies helped symptoms, but they preferred surgical outcomes. June 21, 2022 Q&A: Caring for patients with genetic mutations predisposed to ovarian cancer A Mayo Clinic Obstetrics and Gynecology physician assistant responds to frequent questions from medical professionals about working with patients found to have a hereditary ovarian cancer risk gene. June 21, 2022 The ethics of maternal-fetal medicine surgery Mayo Clinic investigators conducted a review study of 37 peer-reviewed, maternal-fetal surgery papers with ethics discussions published between January 1999 and October 2020. The researchers published findings in a 2022[...] June 21, 2022 Live birth rate similar for frozen donor egg IVF with fresh or frozen sperm Investigators found no statistically significant live birth rate differences between fresh versus frozen ejaculated sperm for intracytoplasmic sperm injection in a frozen donor egg IVF cycle study. June 21, 2022 Postpartum hemorrhage, risks and current management A Mayo Clinic obstetrician discusses postpartum hemorrhage (PPH) measurement, risk factors, treatment and prevention. She presents how Mayo Clinic has managed PPH and when physicians might consider referral. March 15, 2022 Mayo Clinic offers fertility preservation for transgender individuals At Mayo Clinic's campus in Rochester, Minnesota, reproductive endocrinology and infertility specialists provide services to help transgender individuals preserve fertility for later use. Jan. 03, 2022 Link between preterm labor, fetal DNA supported by cell culture research Researchers studying the role cell-free fetal DNA plays in labor report data demonstrate that the concentration of cell-free fetal DNA in blood controls the timing of labor initiation. Dec. 17, 2020 Promoting fetal survival and lung development for severe congenital diaphragmatic hernia Fetoscopic endotracheal occlusion (FETO) transforms lung to head ratio and reduces extracorporeal membrane oxygenation use for fetuses diagnosed with congenital diaphragmatic hernia. Learn about risks, survival rates an[...] Feb. 01, 2019 Evaluation and management of abnormal uterine bleeding Mayo specialists discuss the systematic evaluation of abnormal uterine bleeding using PALM-COEIN etiology in a study published in Mayo Clinic Proceedings. Jan. 18, 2019 Fetal surgery: Early intervention to improve outcomes Rare, congenital anomalies — including pulmonary hypoplasia in congenital diaphragmatic hernia and fetal lower urinary tract obstruction — carry significant risk of mortality and disability. New surgical met[...] Sept. 15, 2018 Steroid cell tumor of the ovary causing renin-mediated hypertension: A case from the endocrine teaching clinics Endocrinologists Oksana Hamidi, D.O., and Todd B. Nippoldt, M.D., discuss the diagnosis and treatment of a 37-year-old woman with a steroid cell tumor — an exceedingly rare sex cord-stromal tumor of the ovary. Medical Professionals Obstetrics & Gynecology News