البحث عن طبيب

Tim Leiner, M.D., Ph.D.

  1. Radiologist
طلب موعد

المنشورات

  1. Zhang H, Leng S, Gao F, Kovalik JP, Tan RS, Wee HN, Chua KV, Ching J, Zhao X, Allen J, Wu Q, Leiner T, Zhong L, Koh AS. Longitudinal aortic strain, ventriculo-arterial coupling and fatty acid oxidation: novel insights into human cardiovascular aging. Geroscience. 2024 Dec; 46 (6):5459-5471 Epub 2024 Mar 22
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  2. Dobrolinska MM, Koetzier LR, Greuter MJW, Vliegenthart R, van der Bie J, Prakken NHJ, Slart RHJA, Leiner T, Budde RPJ, Mastrodicasa D, Booij R, Fleischmann D, Willemink MJ, van Straten M, van der Werf NR. Feasibility of virtual non-iodine coronary calcium scoring on dual source photon-counting coronary CT angiography: a dynamic phantom study. Eur Radiol. 2024 Nov; 34 (11):7429-7437 Epub 2024 May 24
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  3. Woodworth CF, Yee RC, Leiner T. First reported Intra-cavitary right-to-left coronary artery collateral in the context of D-TGA. J Cardiovasc Comput Tomogr. 2024 Nov-Dec; 18 (6):e18-e20 Epub 2024 Sept 27
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  4. van Herten RLM, Lagogiannis I, Leiner T, Isgum I. The role of artificial intelligence in coronary CT angiography. Neth Heart J. 2024 Nov; 32 (11):417-425 Epub 2024 Oct 10
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  5. Abu Rmilah A, Adham A, Ikram-Ul H, Alzu'bi H, Nandan A, Jouni H, Hirashi S, Owen D, Deswal A, Lin SH, Abe JI, Chao TC, Browne J, Leiner T, Laack N, Herrmann J. Novel risk score for predicting acute cardiovascular and cerebrovascular events after chest radiotherapy in patients with breast or lung cancer. Eur J Prev Cardiol. 2024 Oct 25 [Epub ahead of print]
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  6. Dobrolinska MM, Tetteroo PM, Greuter MJW, van Hamersvelt RW, Prakken NHJ, Slart RHJA, Vembar M, Grass M, Leiner T, Velthuis BK, Sucha D, van der Werf NR. The influence of motion-compensated reconstruction on coronary artery analysis for a dual-layer detector CT system: a dynamic phantom study. Eur Radiol. 2024 Aug; 34 (8):4874-4882 Epub 2024 Jan 04
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  7. Raisi-Estabragh Z, Szabo L, McCracken C, Bulow R, Aquaro GD, Andre F, Le TT, Sucha D, Condurache DG, Salih AM, Chadalavada S, Aung N, Lee AM, Harvey NC, Leiner T, Chin CWL, Friedrich MG, Barison A, Dorr M, Petersen SE. Cardiovascular Magnetic Resonance Reference Ranges From the Healthy Hearts Consortium. JACC Cardiovasc Imaging. 2024 Jul; 17 (7):746-762 Epub 2024 Apr 10
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  8. van Duin IAJ, Verheijden RJ, van Diest PJ, Blokx WAM, El-Sharouni MA, Verhoeff JJC, Leiner T, van den Eertwegh AJM, de Groot JWB, van Not OJ, Aarts MJB, van den Berkmortel FWPJ, Blank CU, Haanen JBAG, Hospers GAP, Piersma D, van Rijn RS, van der Veldt AAM, Vreugdenhil G, Wouters MWJM, Stevense-den Boer MAM, Boers-Sonderen MJ, Kapiteijn E, Suijkerbuijk KPM, Elias SG. A prediction model for response to immune checkpoint inhibition in advanced melanoma. Int J Cancer. 2024 May 15; 154 (10):1760-1771 Epub 2024 Jan 31
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  9. Liu LP, Shapira N, Halliburton SS, Meyer S, Perkins A, Litt HI, Kauczor HU, Leiner T, Stiller W, Noel PB. Spectral performance evaluation of a second-generation spectral detector CT. J Appl Clin Med Phys. 2024 Apr; 25 (4):e14300 Epub 2024 Feb 22
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  10. van Herten RLM, Hampe N, Takx RAP, Franssen KJ, Wang YN, Henriques JP, Leiner T, Planken RN, Isgum I. Automatic coronary artery plaque quantification and cad-rads prediction using mesh priors. Ieee Transactions on Medical Imaging. 2024 Apr; 43 (4):1272-83
  11. Zhang H, Leng S, Gao F, Kovalik JP, Wee HN, Chua KV, Ching J, Allen JC, Zhao X, Tan RS, Wu Q, Leiner T, Koh AS, Zhong L. Characteristics of pulmonary artery strain assessed by cardiovascular magnetic resonance imaging and associations with metabolomic pathways in human ageing. Front Cardiovasc Med. 2024; 11:1346443 Epub 2024 Feb 29
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  12. Verpalen VA, Ververs FA, Slieker M, Nuboer R, Swart JF, van der Ent CK, Fejzic Z, Westenberg JJM, Leiner T, Grotenhuis HB, Schipper HS. Enhanced aortic stiffness in adolescents with chronic disease is associated with decreased left ventricular global longitudinal strain. IJC Heart and Vasculature. 2024; 52:101385
  13. van der Werf NR, Dobrolinska MM, Greuter MJW, Willemink MJ, Fleischmann D, Bos D, Slart RHJA, Budoff M, Leiner T. Vendor Independent Coronary Calcium Scoring Improves Individual Risk Assessment: MESA (Multi-Ethnic Study of Atherosclerosis). JACC Cardiovasc Imaging. 2023 Dec; 16 (12):1552-1564 Epub 2023 June 14
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  14. Boonen PT, Buls N, van Gompel G, Devos H, de Brucker Y, Leiner T, Aerden D, de Mey J, Vandemeulebroucke J. Quantitative hemodynamic assessment of stenotic below-the-knee arteries using spatio-temporal bolus tracking on 4D-CT angiography. Med Phys. 2023 Nov; 50 (11):6844-6856 Epub 2023 Sept 26
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  15. Naaktgeboren WR, Stuiver MM, van Harten WH, Aaronson NK, Scott JM, Sonke G, van der Wall E, Velthuis M, Leiner T, Teske AJ, May AM, Groen WG. Effects of exercise during chemotherapy for breast cancer on long-term cardiovascular toxicity. Open Heart. 2023 Oct; 10 (2)
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  16. de Koning MLY, van Dorp P, Assa S, Pundziute-Do Prado G, Voskuil M, Anthonio RL, Veen D, Leiner T, Sibeijn-Kuiper AJ, van Goor H, van Veldhuisen DJ, van der Meer P, Nijveldt R, Lipsic E, van der Harst P. Sodium Thiosulfate in Acute Myocardial Infarction: A Randomized Clinical Trial. JACC Basic Transl Sci. 2023 Oct; 8 (10):1285-1294 Epub 2023 Aug 23
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  17. Bartholomeus GA, van Amsterdam WAC, Harder AMD, Willemink MJ, van Hamersvelt RW, de Jong PA, Leiner T. Robustness of pulmonary nodule radiomic features on computed tomography as a function of varying radiation dose levels-a multi-dose in vivo patient study. Eur Radiol. 2023 Oct; 33 (10):7044-7055 Epub 2023 Apr 19
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  18. Dey D, Arnaout R, Antani S, Badano A, Jacques L, Li H, Leiner T, Margerrison E, Samala R, Sengupta PP, Shah SJ, Slomka P, Williams MC, Bandettini WP, Sachdev V. Proceedings of the NHLBI Workshop on Artificial Intelligence in Cardiovascular Imaging: Translation to Patient Care. JACC Cardiovasc Imaging. 2023 Sep; 16 (9):1209-1223 Epub 2023 July 19
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  19. Sander J, de Vos BD, Bruns S, Planken N, Viergever MA, Leiner T, Isgum I. Reconstruction and completion of high-resolution 3D cardiac shapes using anisotropic CMRI segmentations and continuous implicit neural representations. Comput Biol Med. 2023 Sep; 164:107266 Epub 2023 July 19
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  20. Becker LM, Peper J, Verhappen BJLA, Swart LA, Dedic A, van Dockum WG, van der Ent M, Royaards KJ, Niezen A, Hensen JJ, van Kuijk JP, Mohamed Hoesein FAA, Leiner T, Bruning TA, Swaans MJ. Real world impact of added FFR-CT to coronary CT angiography on clinical decision-making and patient prognosis - IMPACT FFR study. Eur Radiol. 2023 Aug; 33 (8):5465-5475 Epub 2023 Mar 15
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  21. Panda A, Francois CJ, Bookwalter CA, Chaturvedi A, Collins JD, Leiner T, Rajiah PS. Non-Contrast Magnetic Resonance Angiography: Techniques, Principles, and Applications. Magn Reson Imaging Clin N Am. 2023 Aug; 31(3):337-360. Epub 2023 Jun 07.
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  22. Boonen PT, Buls N, Vandemeulebroucke J, Van Gompel G, Van Den Bergh F, Leiner T, Aerden D, de Mey J. Combined evaluation of blood flow and tissue perfusion in diabetic feet by intra-arterial dynamic 4DCT imaging. Eur Radiol Exp. 2023 Jul 26; 7 (1):44 Epub 2023 July 26
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  23. van Duin IAJ, Elias SG, van den Eertwegh AJM, de Groot JWB, Blokx WAM, van Diest PJ, Leiner T, Verhoeff JJC, Verheijden RJ, van Not OJ, Aarts MJB, van den Berkmortel FWPJ, Blank CU, Haanen JBAG, Hospers GAP, Kamphuis AM, Piersma D, van Rijn RS, van der Veldt AAM, Vreugdenhil G, Wouters MWJM, Stevense-den Boer MAM, Boers-Sonderen MJ, Kapiteijn E, Suijkerbuijk KPM. Time interval from primary melanoma to first distant recurrence in relation to patient outcomes in advanced melanoma. Int J Cancer. 2023 Jun 15; 152 (12):2493-2502 Epub 2023 Mar 04
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  24. Rajiah PS, François CJ, Leiner T. Cardiac MRI: State of the Art. Radiology. 2023 May; 307(3):e223008. Epub 2023 Apr 11.
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  25. Singh Y, Farrelly CM, Hathaway QA, Leiner T, Jagtap J, Carlsson GE, Erickson BJ. Topological data analysis in medical imaging: current state of the art. Insights Imaging. 2023 Apr 1; 14 (1):58 Epub 2023 Apr 01
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  26. Peper J, Becker LM, Bruning TA, Budde RPJ, van Dockum WG, Frederix GWJ, Habets J, Henriques JPS, Houthuizen P, Mohamed Hoesein FAA, Planken RN, Voskuil M, Bots ML, Leiner T, Swaans MJ. Rationale and design of the iCORONARY trial: improving the cost-effectiveness of coronary artery disease diagnosis. Neth Heart J. 2023 Apr; 31 (4):150-156 Epub 2023 Jan 31
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  27. Baessler B, Gotz M, Antoniades C, Heidenreich JF, Leiner T, Beer M. Artificial intelligence in coronary computed tomography angiography: Demands and solutions from a clinical perspective. Front Cardiovasc Med. 2023; 10:1120361 Epub 2023 Feb 16
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  28. Vos JL, Leiner T, van Dijk APJ, Pedrizzetti G, Alenezi F, Rodwell L, van der Wegen CTPM, Post MC, Driessen MMP, Nijveldt R. Cardiovascular magnetic resonance-derived left ventricular intraventricular pressure gradients among patients with precapillary pulmonary hypertension. Eur Heart J Cardiovasc Imaging. 2022 Dec 19; 24 (1):78-87
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  29. van Amsterdam WAC, Harlianto NI, Verhoeff JJC, Moeskops P, de Jong PA, Leiner T. The Association between Muscle Quantity and Overall Survival Depends on Muscle Radiodensity: A Cohort Study in Non-Small-Cell Lung Cancer Patients. J Pers Med. 2022 Jul 21; 12 (7) Epub 2022 July 21
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  30. Ververs FA, Eikendal ALM, Kofink D, Nuboer R, Westenberg JJM, Hovenkamp GT, Kemps JJA, Coenen ICJ, Daems JJN, Claus LR, Ju Y, Wulffraat NM, van der Ent CK, Monaco C, Boes M, Leiner T, Grotenhuis HB, Schipper HS. Preclinical Aortic Atherosclerosis in Adolescents With Chronic Disease. J Am Heart Assoc. 2022 Jul 19; 11 (14):e024675 Epub 2022 July 13
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  31. van Vuren A, Kerkhoffs JL, Schols S, Rijneveld A, Nur E, Peereboom D, Gandon Y, Welsing P, van Wijk R, Schutgens R, van Solinge W, Marx J, Leiner T, Biemond B, van Beers E. Proton pump inhibition for secondary hemochromatosis in hereditary anemia: a phase III placebo-controlled randomized cross-over clinical trial. Am J Hematol. 2022 Jul; 97 (7):924-932 Epub 2022 May 10
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  32. Peper J, Becker LM, van den Berg H, Bor WL, Brouwer J, Nijenhuis VJ, van Ginkel DJ, Rensing BJMW, Ten Berg JM, Timmers L, Leiner T, Swaans MJ. Diagnostic Performance of CCTA and CT-FFR for the Detection of CAD in TAVR Work-Up. JACC Cardiovasc Interv. 2022 Jun 13; 15 (11):1140-1149 Epub 2022 May 11
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  33. Collins JD, Rowley H, Leiner T, Reeder S, Hood M, Dekkers I, Tha K, Gulani V, Kopanoglu E, ISMRM MR Safety Committee. Magnetic Resonance Imaging During a Pandemic: Recommendations by the ISMRM Safety Committee. J Magn Reson Imaging. 2022 May; 55 (5):1322-1339 Epub 2021 Dec 20
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  34. Petersen SE, Friedrich MG, Leiner T, Elias MD, Ferreira VM, Fenski M, Flamm SD, Fogel M, Garg R, Halushka MK, Hays AG, Kawel-Boehm N, Kramer CM, Nagel E, Ntusi NAB, Ostenfeld E, Pennell DJ, Raisi-Estabragh Z, Reeder SB, Rochitte CE, Starekova J, Sucha D, Tao Q, Schulz-Menger J, Bluemke DA. Cardiovascular Magnetic Resonance for Patients With COVID-19. JACC Cardiovasc Imaging. 2022 Apr; 15 (4):685-699 Epub 2021 Oct 13
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  35. van der Velden J, Asselbergs FW, Bakkers J, Batkai S, Bertrand L, Bezzina CR, Bot I, Brundel B, Carrier L, Chamuleau S, Ciccarelli M, Dawson D, Davidson SM, Dendorfer A, Duncker DJ, Eschenhagen T, Fabritz L, Falcao-Pires I, Ferdinandy P, Giacca M, Girao H, Gollmann-Tepekoylu C, Gyongyosi M, Guzik TJ, Hamdani N, Heymans S, Hilfiker A, Hilfiker-Kleiner D, Hoekstra AG, Hulot JS, Kuster DWD, van Laake LW, Lecour S, Leiner T, Linke WA, Lumens J, Lutgens E, Madonna R, Maegdefessel L, Mayr M, van der Meer P, Passier R, Perbellini F, Perrino C, Pesce M, Priori S, Remme CA, Rosenhahn B, Schotten U, Schulz R, Sipido K, Sluijter JPG, van Steenbeek F, Steffens S, Terracciano CM, Tocchetti CG, Vlasman P, Yeung KK, Zacchigna S, Zwaagman D, Thum T. Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC working group on myocardial function and the ESC Working Group on Cellular Biology of the Heart. Cardiovasc Res. 2022 Jan 6 Epub 2022 Jan 06
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  36. Henningsson M, Malik S, Botnar R, Castellanos D, Hussain T, Leiner T. Black-Blood Contrast in Cardiovascular MRI. J Magn Reson Imaging. 2022 Jan; 55 (1):61-80 Epub 2020 Oct 19
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  37. van Praagh GD, Wang J, van der Werf NR, Greuter MJW, Mastrodicasa D, Nieman K, van Hamersvelt RW, Oostveen LJ, de Lange F, Slart RHJA, Leiner T, Fleischmann D, Willemink MJ. Coronary Artery Calcium Scoring: Toward a New Standard. Invest Radiol. 2022 Jan 1; 57 (1):13-22
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  38. Hampe N, van Velzen SGM, Planken RN, Henriques JPS, Collet C, Aben JP, Voskuil M, Leiner T, Isgum I. Deep learning-based detection of functionally significant stenosis in coronary CT angiography. Front Cardiovasc Med. 2022; 9:964355 Epub 2022 Nov 15
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  39. Zhai Z, van Velzen SGM, Lessmann N, Planken N, Leiner T, Isgum I. Learning coronary artery calcium scoring in coronary CTA from non-contrast CT using unsupervised domain adaptation. Front Cardiovasc Med. 2022; 9:981901 Epub 2022 Sept 12
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  40. ter Maat LS, van Duin IAJ, Elias SG, van Diest PJ, Pluim JPW, Verhoeff JJC, de Jong PA, Leiner T, Veta M, Suijkerbuijk KPM. Imaging to predict checkpoint inhibitor outcomes in cancer. A systematic review. European Journal of Cancer. 2022; 175:60-76
  41. van der Werf NR, Booij R, Schmidt B, Flohr TG, Leiner T, de Groen JJ, Bos D, Budde RPJ, Willemink MJ, Greuter MJW. Evaluating a calcium-aware kernel for CT CAC scoring with varying surrounding materials and heart rates: a dynamic phantom study. Eur Radiol. 2021 Dec; 31 (12):9211-9220 Epub 2021 May 28
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  42. Huisman M, Ranschaert E, Parker W, Mastrodicasa D, Koci M, Pinto de Santos D, Coppola F, Morozov S, Zins M, Bohyn C, Koc U, Wu J, Veean S, Fleischmann D, Leiner T, Willemink MJ. An international survey on AI in radiology in 1041 radiologists and radiology residents part 2: expectations, hurdles to implementation, and education. Eur Radiol. 2021 Nov; 31 (11):8797-8806 Epub 2021 May 11
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  43. Woudstra OI, Alban FTE, Bijvoet GP, de Bruin-Bon RHACM, Planken RN, Leiner T, Boekholdt SM, Warmerdam EG, Sieswerda GT, Mulder BJM, Bouma BJ, Meijboom FJ. Baffle Complications in Adults After Atrial Switch for Transposition of the Great Arteries. Can J Cardiol. 2021 Oct 9 Epub 2021 Oct 09
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  44. van Velzen SGM, Bruns S, Wolterink JM, Leiner T, Viergever MA, Verkooijen HM, Isgum I. AI-Based Quantification of Planned Radiation Therapy Dose to Cardiac Structures and Coronary Arteries in Patients With Breast Cancer. Int J Radiat Oncol Biol Phys. 2021 Sep 20 Epub 2021 Sept 20
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  45. Huisman M, Ranschaert E, Parker W, Mastrodicasa D, Koci M, Pinto de Santos D, Coppola F, Morozov S, Zins M, Bohyn C, Koc U, Wu J, Veean S, Fleischmann D, Leiner T, Willemink MJ. An international survey on AI in radiology in 1,041 radiologists and radiology residents part 1: fear of replacement, knowledge, and attitude. Eur Radiol. 2021 Sep; 31 (9):7058-7066 Epub 2021 Mar 20
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  46. Xu C, Yi Y, Han Y, Xie H, Lu X, Vembar M, Leiner T, Jin Z, Wang Y. Incremental improvement of diagnostic performance of coronary CT angiography for the assessment of coronary stenosis in the presence of calcium using a dual-layer spectral detector CT: validation by invasive coronary angiography. Int J Cardiovasc Imaging. 2021 Aug; 37 (8):2561-2572 Epub 2021 June 27
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  47. van Praagh GD, van der Werf NR, Wang J, van Ommen F, Poelhekken K, Slart RHJA, Fleischmann D, Greuter MJW, Leiner T, Willemink MJ. Fully automated quantification method (FQM) of coronary calcium in an anthropomorphic phantom. Med Phys. 2021 Jul; 48 (7):3730-3740 Epub 2021 May 17
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  48. Gal R, van Velzen SGM, Hooning MJ, Emaus MJ, van der Leij F, Gregorowitsch ML, Blezer ELA, Gernaat SAM, Lessmann N, Sattler MGA, Leiner T, de Jong PA, Teske AJ, Verloop J, Penninkhof JJ, Vaartjes I, Meijer H, van Tol-Geerdink JJ, Pignol JP, van den Bongard DHJG, Isgum I, Verkooijen HM. Identification of Risk of Cardiovascular Disease by Automatic Quantification of Coronary Artery Calcifications on Radiotherapy Planning CT Scans in Patients With Breast Cancer. JAMA Oncol. 2021 Jul 1; 7 (7):1024-1032
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  49. Weikert T, Francone M, Abbara S, Baessler B, Choi BW, Gutberlet M, Hecht EM, Loewe C, Mousseaux E, Natale L, Nikolaou K, Ordovas KG, Peebles C, Prieto C, Salgado R, Velthuis B, Vliegenthart R, Bremerich J, Leiner T. Machine learning in cardiovascular radiology: ESCR position statement on design requirements, quality assessment, current applications, opportunities, and challenges. Eur Radiol. 2021 Jun; 31(6):3909-3922. Epub 2020 Nov 19.
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  50. de Boer A, Pieters TT, Harteveld AA, Blankestijn PJ, Bos C, Froeling M, Goldschmeding R, Hoogduin HJM, Joles JA, Petri BJ, Verhaar MC, Leiner T, Nguyen TQ, van Zuilen AD. Validation of multiparametric MRI by histopathology after nephrectomy: a case study. MAGMA. 2021 Jun; 34 (3):377-387 Epub 2020 Sept 20
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  51. van 't Klooster CC, van der Graaf Y, Nathoe HM, Bots ML, de Borst GJ, Visseren FLJ, Leiner T, UCC-SMART-study group. Added value of cardiovascular calcifications for prediction of recurrent cardiovascular events and cardiovascular interventions in patients with established cardiovascular disease. Int J Cardiovasc Imaging. 2021 Jun; 37 (6):2051-2061 Epub 2021 Feb 12
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  52. Vigen KK, Reeder SB, Hood MN, Steckner M, Leiner T, Dombroski DA, Gulani V, ISMRM Safety Committee. Recommendations for Imaging Patients With Cardiac Implantable Electronic Devices (CIEDs). J Magn Reson Imaging. 2021 May; 53 (5):1311-1317 Epub 2020 Aug 17
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  53. Wolterink JM, Mukhopadhyay A, Leiner T, Vogl TJ, Bucher AM, Isgum I. Generative Adversarial Networks: A Primer for Radiologists. Radiographics. 2021 May-Jun; 41 (3):840-857 Epub 2021 Apr 23
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  54. Jansz TT, Go MHY, Hartkamp NS, Stoger JL, Celeng C, Leiner T, de Jong PA, Visseren FJL, Verhaar MC, van Jaarsveld BC. Coronary Artery Calcification as a Marker for Coronary Artery Stenosis: Comparing Kidney Failure to the General Population. Kidney Med. 2021 May-Jun; 3 (3):386-394.e1 Epub 2021 Apr 20
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  55. de Baat EC, Naaktgeboren WR, Leiner T, Teske AJ, Habets J, Grotenhuis HB. Update in imaging of cancer therapy-related cardiac toxicity in adults. Open Heart. 2021 Apr; 8 (1)
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  56. Rijnberg FM, van Assen HC, Juffermans JF, Kroft LJM, van den Boogaard PJ, de Koning PJH, Hazekamp MG, van der Woude SFS, Warmerdam EG, Leiner T, Grotenhuis HB, Goeman JJ, Lamb HJ, Roest AAW, Westenberg JJM. Reduced scan time and superior image quality with 3D flow MRI compared to 4D flow MRI for hemodynamic evaluation of the Fontan pathway. Sci Rep. 2021 Mar 22; 11 (1):6507
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  57. Peper J, van Hamersvelt RW, Rensing BJWM, van Kuijk JP, Voskuil M, Berg JMT, Schaap J, Kelder JC, Grobbee DE, Leiner T, Swaans MJ. Diagnostic performance and clinical implications for enhancing a hybrid quantitative flow ratio-FFR revascularization decision-making strategy. Sci Rep. 2021 Mar 19; 11 (1):6425
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  58. de Boer A, Harteveld AA, Stemkens B, Blankestijn PJ, Bos C, Franklin SL, Froeling M, Joles JA, Verhaar MC, van den Berg N, Hoogduin H, Leiner T. Multiparametric Renal MRI: An Intrasubject Test-Retest Repeatability Study. J Magn Reson Imaging. 2021 Mar; 53 (3):859-873 Epub 2020 Apr 16
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  59. Leiner T, Bennink E, Mol CP, Kuijf HJ, Veldhuis WB. Bringing AI to the clinic: blueprint for a vendor-neutral AI deployment infrastructure. Insights Imaging. 2021 Feb 2; 12 (1):11 Epub 2021 Feb 02
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  60. Groepenhoff F, Eikendal ALM, Bots SH, van Ommen AM, Overmars LM, Kapteijn D, Pasterkamp G, Reiber JHC, Hautemann D, Menken R, Wittekoek ME, Hofstra L, Onland-Moret NC, Haitjema S, Hoefer I, Leiner T, den Ruijter HM. Cardiovascular imaging of women and men visiting the outpatient clinic with chest pain or discomfort: design and rationale of the ARGUS Study. BMJ Open. 2020 Dec 15; 10 (12):e040712
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  61. Noothout JMH, De Vos BD, Wolterink JM, Postma EM, Smeets PAM, Takx RAP, Leiner T, Viergever MA, Isgum I. Deep Learning-Based Regression and Classification for Automatic Landmark Localization in Medical Images. IEEE Trans Med Imaging. 2020 Dec; 39 (12):4011-4022 Epub 2020 Nov 30
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  62. Dweck MR, Maurovich-Horvat P, Leiner T, Cosyns B, Fayad ZA, Gijsen FJH, Van der Heiden K, Kooi ME, Maehara A, Muller JE, Newby DE, Narula J, Pontone G, Regar E, Serruys PW, van der Steen AFW, Stone PH, Waltenberger JL, Yuan C, Evans PC, Lutgens E, Wentzel JJ, Back M. Contemporary rationale for non-invasive imaging of adverse coronary plaque features to identify the vulnerable patient: a Position Paper from the European Society of Cardiology Working Group on Atherosclerosis and Vascular Biology and the European Association of Cardiovascular Imaging. Eur Heart J Cardiovasc Imaging. 2020 Oct 20; 21 (11):1177-1183
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  63. Bruns S, Wolterink JM, Takx RAP, van Hamersvelt RW, Sucha D, Viergever MA, Leiner T, Isgum I. Deep learning from dual-energy information for whole-heart segmentation in dual-energy and single-energy non-contrast-enhanced cardiac CT. Med Phys. 2020 Oct; 47 (10):5048-5060 Epub 2020 Aug 27
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  64. Blanken CPS, Westenberg JJM, Aben JP, Bijvoet GP, Chamuleau SAJ, Boekholdt SM, Nederveen AJ, Leiner T, van Ooij P, Planken RN. Quantification of Mitral Valve Regurgitation from 4D Flow MRI Using Semiautomated Flow Tracking. Radiol Cardiothorac Imaging. 2020 Oct; 2 (5):e200004 Epub 2020 Oct 15
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  65. Warmerdam EG, Magni F, Leiner T, Doevendans PA, Sieswerda GT, van Wijk SW, Breur HM, Driesen BW, Grotenhuis HB, Takken T. Echocardiography and MRI parameters associated with exercise capacity in patients after the arterial switch operation. J Cardiol. 2020 Sep; 76 (3):280-286 Epub 2020 May 10
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  66. Peper J, Sucha D, Swaans M, Leiner T. Functional cardiac CT-Going beyond Anatomical Evaluation of Coronary Artery Disease with Cine CT, CT-FFR, CT Perfusion and Machine Learning. Br J Radiol. 2020 Sep 1; 93 (1113):20200349 Epub 2020 Aug 12
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  67. de Boer A, Harteveld AA, Pieters TT, Blankestijn PJ, Bos C, Froeling M, Joles JA, Verhaar MC, Leiner T, Hoogduin H. Decreased native renal T1 up to one week after gadobutrol administration in healthy volunteers. J Magn Reson Imaging. 2020 Aug; 52 (2):622-631 Epub 2019 Dec 04
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  68. Zreik M, van Hamersvelt RW, Khalili N, Wolterink JM, Voskuil M, Viergever MA, Leiner T, Isgum I. Deep Learning Analysis of Coronary Arteries in Cardiac CT Angiography for Detection of Patients Requiring Invasive Coronary Angiography. IEEE Trans Med Imaging. 2020 May; 39 (5):1545-1557 Epub 2019 Nov 12
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  69. van Velzen SGM, Lessmann N, Velthuis BK, Bank IEM, van den Bongard DHJG, Leiner T, de Jong PA, Veldhuis WB, Correa A, Terry JG, Carr JJ, Viergever MA, Verkooijen HM, Isgum I. Deep Learning for Automatic Calcium Scoring in CT: Validation Using Multiple Cardiac CT and Chest CT Protocols. Radiology. 2020 Apr; 295 (1):66-79 Epub 2020 Feb 11
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  70. van 't Klooster CC, Nathoe HM, Hjortnaes J, Bots ML, Isgum I, Lessmann N, van der Graaf Y, Leiner T, Visseren FLJ, UCC-SMART-study group. Multifocal cardiovascular calcification in patients with established cardiovascular disease; prevalence, risk factors, and relation with recurrent cardiovascular disease. Int J Cardiol Heart Vasc. 2020 Apr; 27:100499 Epub 2020 Mar 17
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  71. Warmerdam E, Krings GJ, Leiner T, Grotenhuis HB. Three-dimensional and four-dimensional flow assessment in congenital heart disease. Heart. 2020 Mar; 106 (6):421-426 Epub 2019 Dec 19
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  72. van Laarhoven CJHCM, Rots ML, Pourier VEC, Jorritsma NKN, Leiner T, Hendrikse J, Vergouwen MDI, de Borst GJ. Gadolinium Enhancement of the Aneurysm Wall in Extracranial Carotid Artery Aneurysms. AJNR Am J Neuroradiol. 2020 Mar; 41 (3):501-507 Epub 2020 Feb 27
    View PubMed
  73. Groepenhoff F, Bots SH, Kessler EL, Sickinghe AA, Eikendal ALM, Leiner T, den Ruijter HM. Sex-Specific Aspects in the Pathophysiology and Imaging of Coronary Macro- and Microvascular Disease. J Cardiovasc Transl Res. 2020 Feb; 13 (1):39-46 Epub 2019 Aug 30
    View PubMed
  74. Harteveld AA, de Boer A, Franklin SL, Leiner T, van Stralen M, Bos C. Comparison of multi-delay FAIR and pCASL labeling approaches for renal perfusion quantification at 3T MRI. MAGMA. 2020 Feb; 33 (1):81-94 Epub 2019 Dec 06
    View PubMed
  75. Willemink MJ, Coolen BF, Dyvorne H, Robson PM, Bander I, Ishino S, Pruzan A, Sridhar A, Zhang B, Balchandani P, Mani V, Strijkers GJ, Nederveen AJ, Leiner T, Fayad ZA, Mulder WJM, Calcagno C. Ultra-high resolution, 3-dimensional magnetic resonance imaging of the atherosclerotic vessel wall at clinical 7T. PLoS One. 2020; 15 (12):e0241779 Epub 2020 Dec 14
    View PubMed
  76. Pontone G, De Cecco C, Baggiano A, Guaricci AI, Guglielmo M, Leiner T, Lima J, Maurovich-Horvat P, Muscogiuri G, Nance JW, Schoepf UJ. Design of CTP-PRO study (impact of stress Cardiac computed Tomography myocardial Perfusion on downstream resources and PROgnosis in patients with suspected or known coronary artery disease: A multicenter international study). Int J Cardiol. 2019 Oct 1; 292:253-257 Epub 2019 June 12
    View PubMed
  77. van Hamersvelt RW, Voskuil M, de Jong PA, Willemink MJ, Isgum I, Leiner T. Diagnostic Performance of On-Site Coronary CT Angiography-derived Fractional Flow Reserve Based on Patient-specific Lumped Parameter Models. Radiol Cardiothorac Imaging. 2019 Oct; 1 (4):e190036 Epub 2019 Oct 31
    View PubMed
  78. de Vos BD, Wolterink JM, Leiner T, de Jong PA, Lessmann N, Isgum I. Direct Automatic Coronary Calcium Scoring in Cardiac and Chest CT. IEEE Trans Med Imaging. 2019 Sep; 38 (9):2127-2138 Epub 2019 Feb 18
    View PubMed
  79. Siegersma KR, Leiner T, Chew DP, Appelman Y, Hofstra L, Verjans JW. Artificial intelligence in cardiovascular imaging: state of the art and implications for the imaging cardiologist. Neth Heart J. 2019 Sep; 27 (9):403-413
    View PubMed
  80. Litjens G, Ciompi F, Wolterink JM, de Vos BD, Leiner T, Teuwen J, Isgum I. State-of-the-Art Deep Learning in Cardiovascular Image Analysis. JACC Cardiovasc Imaging. 2019 Aug; 12 (8 Pt 1):1549-1565
    View PubMed
  81. Kooistra NHM, Nijhoff F, Abawi M, Agostoni P, Araya Roos DM, van Tuijl S, Blanken N, Voskuil M, Doevendans PAFM, Stella PR, Leiner T. Ex Vivo Pilot Study of Cardiac Magnetic Resonance Velocity Mapping for Quantification of Aortic Regurgitation in a Porcine Model in the Presence of a Transcatheter Heart Valve. J Cardiovasc Transl Res. 2019 Aug; 12 (4):310-320 Epub 2019 Mar 15
    View PubMed
  82. Celeng C, Leiner T, Maurovich-Horvat P, Merkely B, de Jong P, Dankbaar JW, van Es HW, Ghoshhajra BB, Hoffmann U, Takx RAP. Anatomical and Functional Computed Tomography for Diagnosing Hemodynamically Significant Coronary Artery Disease: A Meta-Analysis. JACC Cardiovasc Imaging. 2019 Jul; 12 (7 Pt 2):1316-1325 Epub 2018 Sept 12
    View PubMed
  83. Zreik M, van Hamersvelt RW, Wolterink JM, Leiner T, Viergever MA, Isgum I. A Recurrent CNN for Automatic Detection and Classification of Coronary Artery Plaque and Stenosis in Coronary CT Angiography. IEEE Trans Med Imaging. 2019 Jul; 38 (7):1588-1598 Epub 2018 Nov 28
    View PubMed
  84. Valstar GB, Bots SH, Groepenhoff F, Gohar A, Rutten FH, Leiner T, Cramer MJM, Teske AJ, Suciadi LP, Menken R, Pasterkamp G, Asselbergs FW, Hofstra L, Bots ML, den Ruijter HM. Discovery of biomarkers for the presence and progression of left ventricular diastolic dysfunction and HEart faiLure with Preserved ejection Fraction in patients at risk for cardiovascular disease: rationale and design of the HELPFul case-cohort study in a Dutch cardiology outpatient clinic. BMJ Open. 2019 Jun 5; 9 (6):e028408 Epub 2019 June 05
    View PubMed
  85. van Hamersvelt RW, Zreik M, Voskuil M, Viergever MA, Isgum I, Leiner T. Deep learning analysis of left ventricular myocardium in CT angiographic intermediate-degree coronary stenosis improves the diagnostic accuracy for identification of functionally significant stenosis. Eur Radiol. 2019 May; 29 (5):2350-2359 Epub 2018 Nov 12
    View PubMed
  86. van Hamersvelt RW, Isgum I, de Jong PA, Cramer MJM, Leenders GEH, Willemink MJ, Voskuil M, Leiner T. Application of speCtraL computed tomogrAphy to impRove specIficity of cardiac compuTed tomographY (CLARITY study): rationale and design. BMJ Open. 2019 Mar 1; 9 (3):e025793 Epub 2019 Mar 01
    View PubMed
  87. Grobben RB, Frima C, Nathoe HM, Leiner T, Kwakkel-van Erp JM, van Klei WA, Peelen LM, van Herwaarden JA. Pulmonary Embolism After Endovascular Aortic Repair, a Retrospective Cohort Study. Eur J Vasc Endovasc Surg. 2019 Feb; 57 (2):304-310 Epub 2018 Oct 20
    View PubMed
  88. Petersen SE, Abdulkareem M, Leiner T. Artificial Intelligence Will Transform Cardiac Imaging-Opportunities and Challenges. Front Cardiovasc Med. 2019; 6:133 Epub 2019 Sept 10
    View PubMed
  89. Hampe N, Wolterink JM, van Velzen SGM, Leiner T, Isgum I. Machine Learning for Assessment of Coronary Artery Disease in Cardiac CT: A Survey. Front Cardiovasc Med. 2019; 6:172 Epub 2019 Nov 26
    View PubMed
  90. Wolterink JM, van Hamersvelt RW, Viergever MA, Leiner T, Isgum I. Coronary artery centerline extraction in cardiac CT angiography using a CNN-based orientation classifier. Med Image Anal. 2019 Jan; 51:46-60 Epub 2018 Oct 22
    View PubMed
  91. Buls N, de Brucker Y, Aerden D, Devos H, Van Gompel G, Boonen PT, Nieboer K, Leiner T, de Mey J. Improving the diagnosis of peripheral arterial disease in below-the-knee arteries by adding time-resolved CT scan series to conventional run-off CT angiography. First experience with a 256-slice CT scanner. Eur J Radiol. 2019 Jan; 110:136-141 Epub 2018 Nov 26
    View PubMed
  92. van den Elshout-den Uyl D, Spoto CPE, de Boer M, Leiner T, Leavis HL, Leguit RJ. First Report of IgG4 Related Disease Primary Presenting as Vertebral Bone Marrow Lesions. Front Immunol. 2019; 10:1910 Epub 2019 Aug 13
    View PubMed
  93. Isgum I, de Vos BD, Wolterink JM, Dey D, Berman DS, Rubeaux M, Leiner T, Slomka PJ. Automatic determination of cardiovascular risk by CT attenuation correction maps in Rb-82 PET/CT. J Nucl Cardiol. 2018 Dec; 25 (6):2133-2142 Epub 2017 Apr 04
    View PubMed
  94. Isgum I, de Vos BD, Wolterink JM, Dey D, Berman DS, Rubeaux M, Leiner T, Slomka PJ. Erratum to: Automatic determination of cardiovascular risk by CT attenuation correction maps in Rb-82 PET/CT. J Nucl Cardiol. 2018 Dec; 25 (6):2143
    View PubMed
  95. den Harder AM, de Boer E, Lagerweij SJ, Boomsma MF, Schilham AMR, Willemink MJ, Milles J, Leiner T, Budde RPJ, de Jong PA. Emphysema quantification using chest CT: influence of radiation dose reduction and reconstruction technique. Eur Radiol Exp. 2018 Nov 7; 2 (1):30 Epub 2018 Nov 07
    View PubMed
  96. Teske AJ, Linschoten M, Kamphuis JAM, Naaktgeboren WR, Leiner T, van der Wall E, Kuball J, van Rhenen A, Doevendans PA, Cramer MJ, Asselbergs FW. Cardio-oncology: an overview on outpatient management and future developments. Neth Heart J. 2018 Nov; 26 (11):521-532
    View PubMed
  97. Vonder M, van der Werf NR, Leiner T, Greuter MJW, Fleischmann D, Vliegenthart R, Oudkerk M, Willemink MJ. The impact of dose reduction on the quantification of coronary artery calcifications and risk categorization: A systematic review. J Cardiovasc Comput Tomogr. 2018 Sep - Oct; 12 (5):352-363 Epub 2018 June 15
    View PubMed
  98. Wolf M, de Boer A, Sharma K, Boor P, Leiner T, Sunder-Plassmann G, Moser E, Caroli A, Jerome NP. Magnetic resonance imaging T1- and T2-mapping to assess renal structure and function: a systematic review and statement paper. Nephrol Dial Transplant. 2018 Sep 1; 33 (suppl_2):ii41-ii50
    View PubMed
  99. Eikendal ALM, Bots ML, Gohar A, Lutgens E, Hoefer IE, den Ruijter HM, Leiner T. Circulating levels of P-selectin and E-selectin relate to cardiovascular magnetic resonance-derived aortic characteristics in young adults from the general population, a cross-sectional study. J Cardiovasc Magn Reson. 2018 Aug 2; 20 (1):54 Epub 2018 Aug 02
    View PubMed
  100. Blanken CPS, Farag ES, Boekholdt SM, Leiner T, Kluin J, Nederveen AJ, van Ooij P, Planken RN. Advanced cardiac MRI techniques for evaluation of left-sided valvular heart disease. J Magn Reson Imaging. 2018 Aug; 48 (2):318-329
    View PubMed
  101. van Hamersvelt RW, Eijsvoogel NG, Mihl C, de Jong PA, Schilham AMR, Buls N, Das M, Leiner T, Willemink MJ. Contrast agent concentration optimization in CTA using low tube voltage and dual-energy CT in multiple vendors: a phantom study. Int J Cardiovasc Imaging. 2018 Aug; 34 (8):1265-1275 Epub 2018 Mar 08
    View PubMed
  102. den Harder AM, de Jong PA, de Groot MCH, Wolterink JM, Budde RPJ, Isgum I, van Solinge WW, Ten Berg MJ, Lutgens E, Veldhuis WB, Haitjema S, Hoefer IE, Leiner T. Commonly available hematological biomarkers are associated with the extent of coronary calcifications. Atherosclerosis. 2018 Aug; 275:166-173 Epub 2018 June 12
    View PubMed
  103. Boccalini S, den Harder AM, Witsenburg M, Breur JPJM, Krestin GP, van Beynum IM, Attrach M, Stagnaro N, Marasini M, de Jong PA, Leiner T, Budde RPJ. Computed tomography image quality of aortic stents in patients with aortic coarctation: a multicentre evaluation. Eur Radiol Exp. 2018 Jul 18; 2 (1):17 Epub 2018 July 18
    View PubMed
  104. Dijkema EJ, Slieker MG, Leiner T, Grotenhuis HB. Arterioventricular interaction after coarctation repair. Am Heart J. 2018 Jul; 201:49-53 Epub 2018 Apr 06
    View PubMed
  105. de Boer A, Leiner T, Vink EE, Blankestijn PJ, van den Berg CAT. Modified dixon-based renal dynamic contrast-enhanced MRI facilitates automated registration and perfusion analysis. Magn Reson Med. 2018 Jul; 80 (1):66-76 Epub 2017 Nov 13
    View PubMed
  106. Gruber B, Froeling M, Leiner T, Klomp DWJ. RF coils: A practical guide for nonphysicists. J Magn Reson Imaging. 2018 Jun 13 Epub 2018 June 13
    View PubMed
  107. Grobben RB, van Waes JAR, Leiner T, Peelen LM, de Borst GJ, Vogely HC, Grobbee DE, Doevendans PA, van Klei WA, Nathoe HM, CHASE Investigators. Unexpected Cardiac Computed Tomography Findings in Patients With Postoperative Myocardial Injury. Anesth Analg. 2018 May; 126 (5):1462-1468
    View PubMed
  108. den Harder AM, de Heer LM, de Jong PA, Suyker WJ, Leiner T, Budde RPJ. Frequency of abnormal findings on routine chest radiography before cardiac surgery. J Thorac Cardiovasc Surg. 2018 May; 155 (5):2035-2040 Epub 2018 Feb 01
    View PubMed
  109. Dijkema EJ, Slieker MG, Breur JMPJ, Leiner T, Grotenhuis HB. Preserved Myocardial Deformation after Successful Coarctation Repair: A CMR Feature-Tracking Study. Pediatr Cardiol. 2018 Mar; 39 (3):555-564 Epub 2017 Dec 05
    View PubMed
  110. Celeng C, de Keizer B, Merkely B, de Jong P, Leiner T, Takx RAP. PET Molecular Targets and Near-Infrared Fluorescence Imaging of Atherosclerosis. Curr Cardiol Rep. 2018 Feb 12; 20 (2):11
    View PubMed
  111. Eikendal ALM, den Ruijter HM, Haaring C, Saam T, van der Geest RJ, Westenberg JJM, Bots ML, Hoefer IE, Leiner T. Sex, body mass index, and blood pressure are related to aortic characteristics in healthy, young adults using magnetic resonance vessel wall imaging: the AMBITYON study. MAGMA. 2018 Feb; 31 (1):173-182 Epub 2017 May 31
    View PubMed
  112. Steensma BR, Voogt IJ, Leiner T, Luijten PR, Habets J, Klomp DWJ, van den Berg CAT, Raaijmakers AJE. An 8-channel Tx/Rx dipole array combined with 16 Rx loops for high-resolution functional cardiac imaging at 7 T. MAGMA. 2018 Feb; 31 (1):7-18 Epub 2017 Nov 24
    View PubMed
  113. Zreik M, Lessmann N, van Hamersvelt RW, Wolterink JM, Voskuil M, Viergever MA, Leiner T, Isgum I. Deep learning analysis of the myocardium in coronary CT angiography for identification of patients with functionally significant coronary artery stenosis. Med Image Anal. 2018 Feb; 44:72-85 Epub 2017 Nov 26
    View PubMed
  114. Driessen MMP, Schings MA, Sieswerda GT, Doevendans PA, Hulzebos EH, Post MC, Snijder RJ, Westenberg JJM, van Dijk APJ, Meijboom FJ, Leiner T. Tricuspid flow and regurgitation in congenital heart disease and pulmonary hypertension: comparison of 4D flow cardiovascular magnetic resonance and echocardiography. J Cardiovasc Magn Reson. 2018 Jan 15; 20 (1):5
    View PubMed
  115. den Harder AM, Willemink MJ, van Doormaal PJ, Wessels FJ, Lock MTWT, Schilham AMR, Budde RPJ, Leiner T, de Jong PA. Radiation dose reduction for CT assessment of urolithiasis using iterative reconstruction: A prospective intra-individual study. Eur Radiol. 2018 Jan; 28 (1):143-150 Epub 2017 July 10
    View PubMed
  116. Dijkema EJ, Sieswerda GT, Takken T, Leiner T, Schoof PH, Haas F, Strengers JLM, Slieker MG. Long-term results of balloon angioplasty for native coarctation of the aorta in childhood in comparison with surgery. Eur J Cardiothorac Surg. 2018 Jan 1; 53 (1):262-268
    View PubMed
  117. Kofink D, Muller SA, Patel RS, Dorresteijn JAN, Berkelmans GFN, de Groot MCH, van Solinge WW, Haitjema S, Leiner T, Visseren FLJ, Hoefer IE, Asselbergs FW, SMART Study Group. Routinely measured hematological parameters and prediction of recurrent vascular events in patients with clinically manifest vascular disease. PLoS One. 2018; 13 (9):e0202682 Epub 2018 Sept 07
    View PubMed
  118. Driessen MMP, Leiner T, Sieswerda GT, van Dijk APJ, Post MC, Friedberg MK, Mertens L, Doevendans PA, Snijder RJ, Hulzebos EH, Meijboom FJ. RV adaptation to increased afterload in congenital heart disease and pulmonary hypertension. PLoS One. 2018; 13 (10):e0205196 Epub 2018 Oct 24
    View PubMed
  119. Sprem J, de Vos BD, Lessmann N, van Hamersvelt RW, Greuter MJW, de Jong PA, Leiner T, Viergever MA, Isgum I. Coronary calcium scoring with partial volume correction in anthropomorphic thorax phantom and screening chest CT images. PLoS One. 2018; 13 (12):e0209318 Epub 2018 Dec 20
    View PubMed
  120. Wolterink JM, Leiner T, Viergever MA, Isgum I. Generative Adversarial Networks for Noise Reduction in Low-Dose CT. IEEE Trans Med Imaging. 2017 Dec; 36 (12):2536-2545 Epub 2017 May 26
    View PubMed
  121. Boccalini S, den Harder AM, Witsenburg M, Breur JMPJ, Krestin GP, van Beynum IM, Stagnaro N, Marasini M, de Jong PA, Leiner T, Budde RPJ. Complications After Stent Placement for Aortic Coarctation: A Pictorial Essay of Computed Tomographic Angiography. J Thorac Imaging. 2017 Nov; 32 (6):W69-W80
    View PubMed
  122. Gho JMIH, van Es R, van Slochteren FJ, Jansen Of Lorkeers SJ, Hauer AJ, van Oorschot JWM, Doevendans PA, Leiner T, Vink A, Asselbergs FW, Chamuleau SAJ. A systematic comparison of cardiovascular magnetic resonance and high resolution histological fibrosis quantification in a chronic porcine infarct model. Int J Cardiovasc Imaging. 2017 Nov; 33 (11):1797-1807 Epub 2017 June 14
    View PubMed
  123. van Hamersvelt RW, Schilham AMR, Engelke K, den Harder AM, de Keizer B, Verhaar HJ, Leiner T, de Jong PA, Willemink MJ. Accuracy of bone mineral density quantification using dual-layer spectral detector CT: a phantom study. Eur Radiol. 2017 Oct; 27 (10):4351-4359 Epub 2017 Apr 03
    View PubMed
  124. van Hamersvelt RW, Willemink MJ, de Jong PA, Milles J, Vlassenbroek A, Schilham AMR, Leiner T. Feasibility and accuracy of dual-layer spectral detector computed tomography for quantification of gadolinium: a phantom study. Eur Radiol. 2017 Sep; 27 (9):3677-3686 Epub 2017 Jan 25
    View PubMed
  125. Pelgrim GJ, van Hamersvelt RW, Willemink MJ, Schmidt BT, Flohr T, Schilham A, Milles J, Oudkerk M, Leiner T, Vliegenthart R. Accuracy of iodine quantification using dual energy CT in latest generation dual source and dual layer CT. Eur Radiol. 2017 Sep; 27 (9):3904-3912 Epub 2017 Feb 06
    View PubMed
  126. Sanders MF, van Doormaal PJ, Beeftink MMA, Bots ML, Fadl Elmula FEM, Habets J, Hammer F, Hoffmann P, Jacobs L, Mark PB, Persu A, Renkin J, Roditi G, Spiering W, Staessen JA, Taylor AH, Verloop WL, Vink EE, Vonken EJ, Voskuil M, Leiner T, Blankestijn PJ, European Network COordinating research on Renal Denervation (ENCOReD) Consortium. Renal artery and parenchymal changes after renal denervation: assessment by magnetic resonance angiography. Eur Radiol. 2017 Sep; 27 (9):3934-3941 Epub 2017 Mar 07
    View PubMed
  127. Smulders MW, Jaarsma C, Nelemans PJ, Bekkers SCAM, Bucerius J, Leiner T, Crijns HJGM, Wildberger JE, Schalla S. Comparison of the prognostic value of negative non-invasive cardiac investigations in patients with suspected or known coronary artery disease-a meta-analysis. Eur Heart J Cardiovasc Imaging. 2017 Sep 1; 18 (9):980-987
    View PubMed
  128. Dijkema EJ, Leiner T, Grotenhuis HB. Diagnosis, imaging and clinical management of aortic coarctation. Heart. 2017 Aug; 103 (15):1148-1155 Epub 2017 Apr 04
    View PubMed
  129. Franssens BT, Hoogduin H, Leiner T, van der Graaf Y, Visseren FLJ. Relation between brown adipose tissue and measures of obesity and metabolic dysfunction in patients with cardiovascular disease. J Magn Reson Imaging. 2017 Aug; 46 (2):497-504 Epub 2017 Jan 27
    View PubMed
  130. de Vos BD, Wolterink JM, de Jong PA, Leiner T, Viergever MA, Isgum I. ConvNet-Based Localization of Anatomical Structures in 3-D Medical Images. IEEE Trans Med Imaging. 2017 Jul; 36 (7):1470-1481 Epub 2017 Feb 23
    View PubMed
  131. van der Sande NGC, Visseren FLJ, van der Graaf Y, Nathoe HM, de Borst GJ, Leiner T, Blankestijn PJ, SMART Study Group. Relation between Kidney Length and Cardiovascular and Renal Risk in High-Risk Patients. Clin J Am Soc Nephrol. 2017 Jun 7; 12 (6):921-928 Epub 2017 May 09
    View PubMed
  132. van Hamersvelt RW, de Jong PA, Dessing TC, Leiner T, Willemink MJ. Dual energy CT to reveal pseudo leakage of frozen elephant trunk. J Cardiovasc Comput Tomogr. 2017 May - Jun; 11 (3):240-241 Epub 2016 Nov 10
    View PubMed
  133. Franssens BT, Nathoe HM, Visseren FL, van der Graaf Y, Leiner T, SMART Study Group. Relation of Epicardial Adipose Tissue Radiodensity to Coronary Artery Calcium on Cardiac Computed Tomography in Patients at High Risk for Cardiovascular Disease. Am J Cardiol. 2017 May 1; 119 (9):1359-1365 Epub 2017 Feb 11
    View PubMed
  134. Ghekiere O, Salgado R, Buls N, Leiner T, Mancini I, Vanhoenacker P, Dendale P, Nchimi A. Image quality in coronary CT angiography: challenges and technical solutions. Br J Radiol. 2017 Apr; 90 (1072):20160567 Epub 2017 Mar 07
    View PubMed
  135. Franssens BT, Nathoe HM, Leiner T, van der Graaf Y, Visseren FL, SMART study group. Relation between cardiovascular disease risk factors and epicardial adipose tissue density on cardiac computed tomography in patients at high risk of cardiovascular events. Eur J Prev Cardiol. 2017 Apr; 24 (6):660-670 Epub 2016 Jan 01
    View PubMed
  136. van Oorschot JW, Guclu F, de Jong S, Chamuleau SA, Luijten PR, Leiner T, Zwanenburg JJ. Endogenous assessment of diffuse myocardial fibrosis in patients with T1rho -mapping. J Magn Reson Imaging. 2017 Jan; 45 (1):132-138 Epub 2016 June 16
    View PubMed
  137. van Eijs MJM, van Zuilen AD, de Boer A, Froeling M, Nguyen TQ, Joles JA, Leiner T, Verhaar MC. Innovative Perspective: Gadolinium-Free Magnetic Resonance Imaging in Long-Term Follow-Up after Kidney Transplantation. Front Physiol. 2017; 8:296 Epub 2017 May 16
    View PubMed
  138. van Hamersvelt RW, den Harder AM, Willemink MJ, Schilham AM, Lammers JJ, Nathoe HM, Budde RP, Leiner T, de Jong PA. Aortic Valve and Thoracic Aortic Calcification Measurements: How Low Can We Go in Radiation Dose? J Comput Assist Tomogr. 2017 Jan; 41 (1):148-155
    View PubMed
  139. den Harder AM, Sucha D, van Doormaal PJ, Budde RPJ, de Jong PA, Schilham AMR, Breur JMPJ, Leiner T. Radiation dose reduction in pediatric great vessel stent computed tomography using iterative reconstruction: A phantom study. PLoS One. 2017; 12 (4):e0175714 Epub 2017 Apr 14
    View PubMed
  140. Wolterink JM, Leiner T, de Vos BD, van Hamersvelt RW, Viergever MA, Isgum I. Automatic coronary artery calcium scoring in cardiac CT angiography using paired convolutional neural networks. Med Image Anal. 2016 Dec; 34:123-136 Epub 2016 Apr 21
    View PubMed
  141. Baggen VJ, Leiner T, Post MC, van Dijk AP, Roos-Hesselink JW, Boersma E, Habets J, Sieswerda GT. Cardiac magnetic resonance findings predicting mortality in patients with pulmonary arterial hypertension: a systematic review and meta-analysis. Eur Radiol. 2016 Nov; 26 (11):3771-3780 Epub 2016 Feb 04
    View PubMed
  142. den Harder AM, Wolterink JM, Willemink MJ, Schilham AMR, de Jong PA, Budde RPJ, Nathoe HM, Isgum I, Leiner T. Submillisievert coronary calcium quantification using model-based iterative reconstruction: A within-patient analysis. Eur J Radiol. 2016 Nov; 85 (11):2152-2159 Epub 2016 Sept 30
    View PubMed
  143. van Oorschot JW, Visser F, Eikendal AL, Vonken EJ, Luijten PR, Chamuleau SA, Leiner T, Zwanenburg JJ. Single Breath-Hold T1rho-Mapping of the Heart for Endogenous Assessment of Myocardial Fibrosis. Invest Radiol. 2016 Aug; 51 (8):505-12
    View PubMed
  144. den Harder AM, Willemink MJ, de Jong PA, Schilham AM, Rajiah P, Takx RA, Leiner T. New horizons in cardiac CT. Clin Radiol. 2016 Aug; 71 (8):758-67 Epub 2016 Feb 28
    View PubMed
  145. Maas AH, Ottevanger N, Atsma F, Cramer MJ, Leiner T, Poortmans P. Cardiovascular surveillance in breast cancer treatment: A more individualized approach is needed. Maturitas. 2016 Jul; 89:58-62 Epub 2016 Apr 23
    View PubMed
  146. Celeng C, Maurovich-Horvat P, Ghoshhajra BB, Merkely B, Leiner T, Takx RA. Prognostic Value of Coronary Computed Tomography Angiography in Patients With Diabetes: A Meta-analysis. Diabetes Care. 2016 Jul; 39 (7):1274-80
    View PubMed
  147. den Harder AM, Willemink MJ, van Hamersvelt RW, Vonken EP, Schilham AM, Lammers JW, Luijk B, Budde RP, Leiner T, de Jong PA. Pulmonary Nodule Volumetry at Different Low Computed Tomography Radiation Dose Levels With Hybrid and Model-Based Iterative Reconstruction: A Within Patient Analysis. J Comput Assist Tomogr. 2016 Jul-Aug; 40 (4):578-83
    View PubMed
  148. de Boer A, Hoogduin JM, Blankestijn PJ, Li X, Luijten PR, Metzger GJ, Raaijmakers AJ, Umutlu L, Visser F, Leiner T. 7 T renal MRI: challenges and promises. MAGMA. 2016 Jun; 29 (3):417-33 Epub 2016 Mar 23
    View PubMed
  149. den Harder AM, de Heer LM, Maurovich-Horvat P, Merkely B, de Jong PA, Das M, de Wit GA, Leiner T, Budde RP, CRICKET Investigators. Ultra low-dose chest ct with iterative reconstructions as an alternative to conventional chest x-ray prior to heart surgery (CRICKET study): Rationale and design of a multicenter randomized trial. J Cardiovasc Comput Tomogr. 2016 May-Jun; 10 (3):242-5 Epub 2016 Jan 30
    View PubMed
  150. Wolterink JM, Leiner T, de Vos BD, Coatrieux JL, Kelm BM, Kondo S, Salgado RA, Shahzad R, Shu H, Snoeren M, Takx RA, van Vliet LJ, van Walsum T, Willems TP, Yang G, Zheng Y, Viergever MA, Isgum I. An evaluation of automatic coronary artery calcium scoring methods with cardiac CT using the orCaScore framework. Med Phys. 2016 May; 43 (5):2361
    View PubMed
  151. Eikendal AL, Blomberg BA, Haaring C, Saam T, van der Geest RJ, Visser F, Bots ML, den Ruijter HM, Hoefer IE, Leiner T. 3D black blood VISTA vessel wall cardiovascular magnetic resonance of the thoracic aorta wall in young, healthy adults: reproducibility and implications for efficacy trial sample sizes: a cross-sectional study. J Cardiovasc Magn Reson. 2016 Apr 14; 18:20
    View PubMed
  152. Willemink MJ, Leiner T, Maurovich-Horvat P. Cardiac CT Imaging of Plaque Vulnerability: Hype or Hope? Curr Cardiol Rep. 2016 Apr; 18 (4):37
    View PubMed
  153. den Harder AM, de Heer LM, Meijer RC, Das M, Krestin GP, Maessen JG, Bogers AJ, de Jong PA, Leiner T, Budde RP. Effect of computed tomography before cardiac surgery on surgical strategy, mortality and stroke. Eur J Radiol. 2016 Apr; 85 (4):744-50 Epub 2016 Jan 14
    View PubMed
  154. Maas AH, Leiner T. Gender and age-specific focus needed for cardiovascular outcome measures to improve life-time prevention in high risk women. Maturitas. 2016 Apr; 86:74-6 Epub 2016 Jan 28
    View PubMed
  155. Braber TL, Willemink MJ, Bohte EH, Mosterd A, Leiner T, Velthuis BK. Assessment of Coronary Artery Calcium on Low-Dose Coronary Computed Tomography Angiography With Iterative Reconstruction. J Comput Assist Tomogr. 2016 Mar-Apr; 40 (2):266-71
    View PubMed
  156. Mooiweer R, Sbrizzi A, El Aidi H, Eikendal AL, Raaijmakers A, Visser F, van den Berg CA, Leiner T, Luijten PR, Hoogduin H. Fast 3D isotropic imaging of the aortic vessel wall by application of 2D spatially selective excitation and a new way of inversion recovery for black blood imaging. Magn Reson Med. 2016 Feb; 75 (2):547-55 Epub 2015 Mar 11
    View PubMed
  157. Den Harder AM, Willemink MJ, van Hamersvelt RW, Vonken EJ, Milles J, Schilham AM, Lammers JW, de Jong PA, Leiner T, Budde RP. Effect of radiation dose reduction and iterative reconstruction on computer-aided detection of pulmonary nodules: Intra-individual comparison. Eur J Radiol. 2016 Feb; 85 (2):346-51 Epub 2015 Dec 07
    View PubMed
  158. Den Harder AM, Willemink MJ, De Ruiter QM, De Jong PA, Schilham AM, Krestin GP, Leiner T, Budde RP. Dose reduction with iterative reconstruction for coronary CT angiography: a systematic review and meta-analysis. Br J Radiol. 2016; 89 (1058):20150068 Epub 2015 Nov 12
    View PubMed
  159. Lohrke J, Frenzel T, Endrikat J, Alves FC, Grist TM, Law M, Lee JM, Leiner T, Li KC, Nikolaou K, Prince MR, Schild HH, Weinreb JC, Yoshikawa K, Pietsch H. 25 Years of Contrast-Enhanced MRI: Developments, Current Challenges and Future Perspectives. Adv Ther. 2016 Jan; 33 (1):1-28 Epub 2016 Jan 25
    View PubMed
  160. Willemink MJ, den Harder AM, Foppen W, Schilham AM, Rienks R, Laufer EM, Nieman K, de Jong PA, Budde RP, Nathoe HM, Leiner T. Finding the optimal dose reduction and iterative reconstruction level for coronary calcium scoring. J Cardiovasc Comput Tomogr. 2016 Jan-Feb; 10 (1):69-75 Epub 2015 Aug 28
    View PubMed
  161. Franssens BT, Eikendal AL, Leiner T, van der Graaf Y, Visseren FL, Hoogduin JM. Reliability and agreement of adipose tissue fat fraction measurements with water-fat MRI in patients with manifest cardiovascular disease. NMR Biomed. 2016 Jan; 29 (1):48-56 Epub 2015 Dec 01
    View PubMed
  162. Eikendal AL, Bots ML, Haaring C, Saam T, van der Geest RJ, Westenberg JJ, den Ruijter HM, Hoefer IE, Leiner T. Reference Values for Cardiac and Aortic Magnetic Resonance Imaging in Healthy, Young Caucasian Adults. PLoS One. 2016; 11 (10):e0164480 Epub 2016 Oct 12
    View PubMed
  163. Gernaat SA, Isgum I, de Vos BD, Takx RA, Young-Afat DA, Rijnberg N, Grobbee DE, van der Graaf Y, de Jong PA, Leiner T, van den Bongard DH, Pignol JP, Verkooijen HM. Automatic Coronary Artery Calcium Scoring on Radiotherapy Planning CT Scans of Breast Cancer Patients: Reproducibility and Association with Traditional Cardiovascular Risk Factors. PLoS One. 2016; 11 (12):e0167925 Epub 2016 Dec 09
    View PubMed
  164. Takx RA, Sucha D, Park J, Leiner T, Hoffmann U. Sublingual Nitroglycerin Administration in Coronary Computed Tomography Angiography: a Systematic Review. Eur Radiol. 2015 Dec; 25 (12):3536-42 Epub 2015 May 21
    View PubMed
  165. Sucha D, Tuncay V, Prakken NH, Leiner T, van Ooijen PM, Oudkerk M, Budde RP. Does the aortic annulus undergo conformational change throughout the cardiac cycle? A systematic review. Eur Heart J Cardiovasc Imaging. 2015 Dec; 16 (12):1307-17 Epub 2015 Sept 15
    View PubMed
  166. Willemink MJ, Eldib M, Leiner T, Fayad ZA, Mani V. Do carotid MR surface coils affect PET quantification in PET/MR imaging? EJNMMI Phys. 2015 Dec; 2 (Suppl 1):A34
    View PubMed
  167. den Harder AM, Willemink MJ, de Ruiter QM, Schilham AM, Krestin GP, Leiner T, de Jong PA, Budde RP. Achievable dose reduction using iterative reconstruction for chest computed tomography: A systematic review. Eur J Radiol. 2015 Nov; 84 (11):2307-13 Epub 2015 July 17
    View PubMed
  168. Baggen VJ, Driessen MM, Meijboom FJ, Sieswerda GT, Jansen NJ, van Wijk SW, Doevendans PA, Leiner T, Schoof PH, Takken T, Breur JM. Main pulmonary artery area limits exercise capacity in patients long-term after arterial switch operation. J Thorac Cardiovasc Surg. 2015 Oct; 150 (4):918-25 Epub 2015 Aug 06
    View PubMed
  169. Sucha D, Symersky P, Tanis W, Mali WP, Leiner T, van Herwerden LA, Budde RP. Multimodality Imaging Assessment of Prosthetic Heart Valves. Circ Cardiovasc Imaging. 2015 Sep; 8 (9):e003703
    View PubMed
  170. Wolterink JM, Leiner T, Takx RA, Viergever MA, Isgum I. Automatic Coronary Calcium Scoring in Non-Contrast-Enhanced ECG-Triggered Cardiac CT With Ambiguity Detection. IEEE Trans Med Imaging. 2015 Sep; 34 (9):1867-78 Epub 2015 Mar 16
    View PubMed
  171. Willemink MJ, Abramiuc B, den Harder AM, van der Werf NR, de Jong PA, Budde RP, Wildberger JE, Vliegenthart R, Willems TP, Greuter MJ, Leiner T. Coronary calcium scores are systematically underestimated at a large chest size: A multivendor phantom study. J Cardiovasc Comput Tomogr. 2015 Sep-Oct; 9 (5):415-21 Epub 2015 Apr 02
    View PubMed
  172. Willemink MJ, Takx RA, Isgum I, de Koning HJ, Oudkerk M, Mali WP, Budde RP, Leiner T, Vliegenthart R, de Jong PA. Prognostic value of heart valve calcifications for cardiovascular events in a lung cancer screening population. Int J Cardiovasc Imaging. 2015 Aug; 31 (6):1243-9 Epub 2015 May 12
    View PubMed
  173. den Harder AM, Willemink MJ, Budde RP, Schilham AM, Leiner T, de Jong PA. Hybrid and model-based iterative reconstruction techniques for pediatric CT. AJR Am J Roentgenol. 2015 Mar; 204 (3):645-53
    View PubMed
  174. Driessen MM, Breur JM, Budde RP, van Oorschot JW, van Kimmenade RR, Sieswerda GT, Meijboom FJ, Leiner T. Advances in cardiac magnetic resonance imaging of congenital heart disease. Pediatr Radiol. 2015 Jan; 45 (1):5-19 Epub 2015 Jan 01
    View PubMed
  175. Takx RA, Blomberg BA, El Aidi H, Habets J, de Jong PA, Nagel E, Hoffmann U, Leiner T. Diagnostic accuracy of stress myocardial perfusion imaging compared to invasive coronary angiography with fractional flow reserve meta-analysis. Circ Cardiovasc Imaging. 2015 Jan; 8 (1)
    View PubMed
  176. Takx RA, Vliegenthart R, Mohamed Hoesein FA, Isgum I, de Koning HJ, Mali WP, van der Aalst CM, Zanen P, Lammers JW, Groen HJ, van Rikxoort EM, Schmidt M, van Ginneken B, Oudkerk M, Leiner T, de Jong PA. Pulmonary function and CT biomarkers as risk factors for cardiovascular events in male lung cancer screening participants: the NELSON study. Eur Radiol. 2015 Jan; 25 (1):65-71 Epub 2014 Sept 03
    View PubMed
  177. Takx RA, Zanen P, Leiner T, van der Graaf Y, de Jong PA, SMART study group. The interdependence between cardiovascular calcifications in different arterial beds and vascular risk factors in patients at high cardiovascular risk. Atherosclerosis. 2015 Jan; 238 (1):140-6 Epub 2014 Nov 29
    View PubMed
  178. Takx RA, Isgum I, Willemink MJ, van der Graaf Y, de Koning HJ, Vliegenthart R, Oudkerk M, Leiner T, de Jong PA. Quantification of coronary artery calcium in nongated CT to predict cardiovascular events in male lung cancer screening participants: results of the NELSON study. J Cardiovasc Comput Tomogr. 2015 Jan-Feb; 9 (1):50-7 Epub 2014 Nov 20
    View PubMed
  179. Jansen of Lorkeers SJ, Gho JM, Koudstaal S, van Hout GP, Zwetsloot PP, van Oorschot JW, van Eeuwijk EC, Leiner T, Hoefer IE, Goumans MJ, Doevendans PA, Sluijter JP, Chamuleau SA. Xenotransplantation of Human Cardiomyocyte Progenitor Cells Does Not Improve Cardiac Function in a Porcine Model of Chronic Ischemic Heart Failure. Results from a Randomized, Blinded, Placebo Controlled Trial. PLoS One. 2015; 10 (12):e0143953 Epub 2015 Dec 17
    View PubMed
  180. van Oorschot JW, El Aidi H, Jansen of Lorkeers SJ, Gho JM, Froeling M, Visser F, Chamuleau SA, Doevendans PA, Luijten PR, Leiner T, Zwanenburg JJ. Endogenous assessment of chronic myocardial infarction with T(1rho)-mapping in patients. J Cardiovasc Magn Reson. 2014 Dec 20; 16:104
    View PubMed
  181. Willemink MJ, Vliegenthart R, Takx RA, Leiner T, Budde RP, Bleys RL, Das M, Wildberger JE, Prokop M, Buls N, de Mey J, Schilham AM, de Jong PA. Coronary artery calcification scoring with state-of-the-art CT scanners from different vendors has substantial effect on risk classification. Radiology. 2014 Dec; 273 (3):695-702 Epub 2014 Aug 22
    View PubMed
  182. Willemink MJ, Takx RA, de Jong PA, Budde RP, Bleys RL, Das M, Wildberger JE, Prokop M, Buls N, de Mey J, Leiner T, Schilham AM. Computed tomography radiation dose reduction: effect of different iterative reconstruction algorithms on image quality. J Comput Assist Tomogr. 2014 Nov-Dec; 38 (6):815-23
    View PubMed
  183. Salgado RA, Budde RP, Leiner T, Shivalkar B, Van Herck PL, Op de Beeck BJ, Vrints C, Buijsrogge MP, Stella PR, Rodrigus I, Bosmans J, Parizel PM. Transcatheter aortic valve replacement: postoperative CT findings of Sapien and CoreValve transcatheter heart valves. Radiographics. 2014 Oct; 34 (6):1517-36
    View PubMed
  184. Eikendal AL, den Ruijter HM, Uiterwaal CS, Pasterkamp G, Hoefer IE, de Kleijn DP, Schoneveld AH, Leiner T, Bots ML, Visseren FL, Evelein AM. Extracellular vesicle protein CD14 relates to common carotid intima-media thickness in eight-year-old children. Atherosclerosis. 2014 Oct; 236 (2):270-6 Epub 2014 July 28
    View PubMed
  185. Willemink MJ, Takx RA, de Jong PA, Budde RP, Bleys RL, Das M, Wildberger JE, Prokop M, Buls N, de Mey J, Schilham AM, Leiner T. The impact of CT radiation dose reduction and iterative reconstruction algorithms from four different vendors on coronary calcium scoring. Eur Radiol. 2014 Sep; 24 (9):2201-12 Epub 2014 June 03
    View PubMed
  186. Schrover IM, Leiner T, Klomp DW, Wijnen JP, Uiterwaal CS, Spiering W, Visseren FL. Feasibility and reproducibility of free fatty acid profiling in abdominal adipose tissue with 1H-magnetic resonance spectroscopy at 3 T: differences between lean and obese individuals. J Magn Reson Imaging. 2014 Aug; 40 (2):423-31 Epub 2013 Sept 23
    View PubMed
  187. den Harder AM, Willemink MJ, Bleys RL, de Jong PA, Budde RP, Schilham AM, Leiner T. Dose reduction for coronary calcium scoring with hybrid and model-based iterative reconstruction: an ex vivo study. Int J Cardiovasc Imaging. 2014 Aug; 30 (6):1125-33 Epub 2014 May 03
    View PubMed
  188. van Hamersvelt RW, Willemink MJ, Takx RA, Eikendal AL, Budde RP, Leiner T, Mol CP, Isgum I, de Jong PA. Cardiac valve calcifications on low-dose unenhanced ungated chest computed tomography: inter-observer and inter-examination reliability, agreement and variability. Eur Radiol. 2014 Jul; 24 (7):1557-64 Epub 2014 May 10
    View PubMed
  189. Nguyen VL, Backes WH, Kooi ME, Wishaupt MC, Hellenthal FA, Bosboom EM, van der Geest RJ, Schurink GW, Leiner T. Quantification of abdominal aortic aneurysm wall enhancement with dynamic contrast-enhanced MRI: feasibility, reproducibility, and initial experience. J Magn Reson Imaging. 2014 Jun; 39 (6):1449-56 Epub 2013 Oct 22
    View PubMed
  190. Sucha D, Willemink MJ, de Jong PA, Schilham AM, Leiner T, Symersky P, Budde RP. The impact of a new model-based iterative reconstruction algorithm on prosthetic heart valve related artifacts at reduced radiation dose MDCT. Int J Cardiovasc Imaging. 2014 Apr; 30 (4):785-93 Epub 2014 Jan 29
    View PubMed
  191. El Aidi H, Adams A, Moons KG, Den Ruijter HM, Mali WP, Doevendans PA, Nagel E, Schalla S, Bots ML, Leiner T. Cardiac magnetic resonance imaging findings and the risk of cardiovascular events in patients with recent myocardial infarction or suspected or known coronary artery disease: a systematic review of prognostic studies. J Am Coll Cardiol. 2014 Mar 25; 63 (11):1031-45 Epub 2014 Jan 30
    View PubMed
  192. Driessen MM, Baggen VJ, Freling HG, Pieper PG, van Dijk AP, Doevendans PA, Snijder RJ, Post MC, Meijboom FJ, Sieswerda GT, Leiner T, Willems TP. Pressure overloaded right ventricles: a multicenter study on the importance of trabeculae in RV function measured by CMR. Int J Cardiovasc Imaging. 2014 Mar; 30 (3):599-608 Epub 2014 Jan 20
    View PubMed
  193. Willemink MJ, Meijs MF, Cramer MJ, Thijssen AS, Moll FL, de Jong PA, Leiner T, Budde RP. Coronary artery assessment on electrocardiogram-gated thoracoabdominal multidetector computed tomographic angiography for aortic evaluation. J Comput Assist Tomogr. 2014 Mar-Apr; 38 (2):185-9
    View PubMed
  194. Takx RA, Willemink MJ, Nathoe HM, Schilham AM, Budde RP, de Jong PA, Leiner T. The effect of iterative reconstruction on quantitative computed tomography assessment of coronary plaque composition. Int J Cardiovasc Imaging. 2014 Jan; 30 (1):155-63 Epub 2013 Sept 18
    View PubMed
  195. Versluis B, Nelemans PJ, Brans R, Wildberger JE, Schurink GW, Leiner T, Backes WH. Functional MRI in peripheral arterial disease: arterial peak flow versus ankle-brachial index. PLoS One. 2014; 9 (2):e88471 Epub 2014 Feb 05
    View PubMed
  196. Takx RA, de Jong PA, Leiner T, Oudkerk M, de Koning HJ, Mol CP, Viergever MA, Isgum I. Automated coronary artery calcification scoring in non-gated chest CT: agreement and reliability. PLoS One. 2014; 9 (3):e91239 Epub 2014 Mar 13
    View PubMed
  197. Willemink MJ, den Harder AM, de Jong PA, Leiner T. [The future of the CT scan; will CT replace conventional radiography?]. Ned Tijdschr Geneeskd. 2014; 158:A7438
    View PubMed
  198. Versluis B, Leiner T, Nelemans PJ, Wildberger JE, Schurink GW, Backes WH. Magnetic resonance imaging-based monitoring of collateral artery development in patients with intermittent claudication during supervised exercise therapy. J Vasc Surg. 2013 Nov; 58 (5):1236-43 Epub 2013 Mar 21
    View PubMed
  199. Leiner T, Habets J, Versluis B, Geerts L, Alberts E, Blanken N, Hendrikse J, Vonken EJ, Eggers H. Subtractionless first-pass single contrast medium dose peripheral MR angiography using two-point Dixon fat suppression. Eur Radiol. 2013 Aug; 23 (8):2228-35 Epub 2013 Apr 17
    View PubMed
  200. Willemink MJ, de Jong PA, Leiner T, de Heer LM, Nievelstein RA, Budde RP, Schilham AM. Iterative reconstruction techniques for computed tomography Part 1: technical principles. Eur Radiol. 2013 Jun; 23 (6):1623-31 Epub 2013 Jan 12
    View PubMed
  201. Willemink MJ, Leiner T, de Jong PA, de Heer LM, Nievelstein RA, Schilham AM, Budde RP. Iterative reconstruction techniques for computed tomography part 2: initial results in dose reduction and image quality. Eur Radiol. 2013 Jun; 23 (6):1632-42 Epub 2013 Jan 16
    View PubMed
  202. Willemink MJ, Schilham AM, Leiner T, Mali WP, de Jong PA, Budde RP. Iterative reconstruction does not substantially delay CT imaging in an emergency setting. Insights Imaging. 2013 Jun; 4 (3):391-7 Epub 2013 Feb 16
    View PubMed
  203. Willemink MJ, Habets J, de Jong PA, Schilham AM, Mali WP, Leiner T, Budde RP. Iterative reconstruction improves evaluation of native aortic and mitral valves by retrospectively ECG-gated thoracoabdominal CTA. Eur Radiol. 2013 Apr; 23 (4):968-74 Epub 2012 Oct 13
    View PubMed
  204. Gerretsen S, Kessels AG, Nelemans PJ, Dijkstra J, Reiber JH, van der Geest RJ, Katoh M, Waltenberger J, van Engelshoven JM, Botnar RM, Kooi ME, Leiner T. Detection of coronary plaques using MR coronary vessel wall imaging: validation of findings with intravascular ultrasound. Eur Radiol. 2013 Jan; 23 (1):115-24 Epub 2012 July 11
    View PubMed
  205. Willemink MJ, Borstlap J, Takx RA, Schilham AM, Leiner T, Budde RP, de Jong PA. The effects of computed tomography with iterative reconstruction on solid pulmonary nodule volume quantification. PLoS One. 2013; 8 (2):e58053 Epub 2013 Feb 27
    View PubMed
  206. Versluis B, Tuinder S, Boetes C, Van Der Hulst R, Lataster A, Van Mulken T, Wildberger J, de Haan M, Leiner T. Equilibrium-phase high spatial resolution contrast-enhanced MR angiography at 1.5T in preoperative imaging for perforator flap breast reconstruction. PLoS One. 2013; 8 (8):e71286 Epub 2013 Aug 29
    View PubMed
  207. Nguyen VL, Kooi ME, Backes WH, van Hoof RH, Saris AE, Wishaupt MC, Hellenthal FA, van der Geest RJ, Kessels AG, Schurink GW, Leiner T. Suitability of pharmacokinetic models for dynamic contrast-enhanced MRI of abdominal aortic aneurysm vessel wall: a comparison. PLoS One. 2013; 8 (10):e75173 Epub 2013 Oct 02
    View PubMed
  208. Leiner T, de Jong PA, Nievelstein R. [CT scans in children and adolescents: only when appropriate and when optimized]. Ned Tijdschr Geneeskd. 2013; 157 (49):A6711
    View PubMed
  209. Habets J, Symersky P, Leiner T, de Mol BA, Mali WP, Budde RP. Artifact reduction strategies for prosthetic heart valve CT imaging. Int J Cardiovasc Imaging. 2012 Dec; 28 (8):2099-108 Epub 2012 Apr 05
    View PubMed
  210. Willemink MJ, Leiner T, Budde RP, de Kort FP, Vliegenthart R, van Ooijen PM, Oudkerk M, de Jong PA. Systematic error in lung nodule volumetry: effect of iterative reconstruction versus filtered back projection at different CT parameters. AJR Am J Roentgenol. 2012 Dec; 199 (6):1241-6
    View PubMed
  211. Mets OM, Willemink MJ, de Kort FP, Mol CP, Leiner T, Oudkerk M, Prokop M, de Jong PA. The effect of iterative reconstruction on computed tomography assessment of emphysema, air trapping and airway dimensions. Eur Radiol. 2012 Oct; 22 (10):2103-9 Epub 2012 May 23
    View PubMed
  212. de Jong PA, Leiner T, Lammers JW, Gietema HA. Can low-dose unenhanced chest CT be used for follow-up of lung nodules? AJR Am J Roentgenol. 2012 Oct; 199 (4):777-80
    View PubMed
  213. Habets J, Symersky P, de Mol BA, Mali WP, Leiner T, Budde RP. A novel iterative reconstruction algorithm allows reduced dose multidetector-row CT imaging of mechanical prosthetic heart valves. Int J Cardiovasc Imaging. 2012 Aug; 28 (6):1567-75 Epub 2011 Oct 15
    View PubMed
  214. Versteylen MO, Takx RA, Joosen IA, Nelemans PJ, Das M, Crijns HJ, Hofstra L, Leiner T. Epicardial adipose tissue volume as a predictor for coronary artery disease in diabetic, impaired fasting glucose, and non-diabetic patients presenting with chest pain. Eur Heart J Cardiovasc Imaging. 2012 Jun; 13 (6):517-23 Epub 2012 Feb 05
    View PubMed
  215. Jaarsma C, Leiner T, Bekkers SC, Crijns HJ, Wildberger JE, Nagel E, Nelemans PJ, Schalla S. Diagnostic performance of noninvasive myocardial perfusion imaging using single-photon emission computed tomography, cardiac magnetic resonance, and positron emission tomography imaging for the detection of obstructive coronary artery disease: a meta-analysis. J Am Coll Cardiol. 2012 May 8; 59 (19):1719-28
    View PubMed
  216. Jaspers K, Slenter JM, Leiner T, Wagenaar A, Post MJ, Backes WH. Automated multiscale vessel analysis for the quantification of MR angiography of peripheral arteriogenesis. J Magn Reson Imaging. 2012 Feb; 35 (2):379-86 Epub 2011 Nov 01
    View PubMed
  217. Versteylen MO, Bekkers SC, Smulders MW, Winkens B, Mihl C, Winkens MH, Leiner T, Waltenberger JL, Kim RJ, Gorgels AP. Performance of angiographic, electrocardiographic and MRI methods to assess the area at risk in acute myocardial infarction. Heart. 2012 Jan; 98 (2):109-15 Epub 2011 Sept 19
    View PubMed
  218. Versluis B, Dremmen MH, Nelemans PJ, Wildberger JE, Schurink GW, Leiner T, Backes WH. MRI of arterial flow reserve in patients with intermittent claudication: feasibility and initial experience. PLoS One. 2012; 7 (3):e31514 Epub 2012 Mar 08
    View PubMed
  219. Versluis B, Dremmen MH, Nelemans PJ, Wildberger JE, Schurink GW, Leiner T, Backes WH. Dynamic contrast-enhanced MRI assessment of hyperemic fractional microvascular blood plasma volume in peripheral arterial disease: initial findings. PLoS One. 2012; 7 (5):e37756 Epub 2012 May 25
    View PubMed
  220. Joosen IA, Schiphof F, Versteylen MO, Laufer EM, Winkens MH, Nelemans PJ, Kooman JP, Hofstra L, Wildberger JE, Leiner T. Relation between mild to moderate chronic kidney disease and coronary artery disease determined with coronary CT angiography. PLoS One. 2012; 7 (10):e47267 Epub 2012 Oct 10
    View PubMed
  221. Schrauwen-Hinderling VB, Meex RC, Hesselink MK, van de Weijer T, Leiner T, Schar M, Lamb HJ, Wildberger JE, Glatz JF, Schrauwen P, Kooi ME. Cardiac lipid content is unresponsive to a physical activity training intervention in type 2 diabetic patients, despite improved ejection fraction. Cardiovasc Diabetol. 2011 May 26; 10:47
    View PubMed
  222. Budde RP, Krings GJ, Leiner T. Prospectively ECG-triggered 256-slice computed tomography findings in a patient with dextrocardia, stent-treated coarctation, and infracardial right-sided pulmonary vein deviation. Eur Heart J. 2011 May; 32 (10):1213 Epub 2010 Dec 23
    View PubMed
  223. Lambregts DM, Beets GL, Maas M, Kessels AG, Bakers FC, Cappendijk VC, Engelen SM, Lahaye MJ, de Bruine AP, Lammering G, Leiner T, Verwoerd JL, Wildberger JE, Beets-Tan RG. Accuracy of gadofosveset-enhanced MRI for nodal staging and restaging in rectal cancer. Ann Surg. 2011 Mar; 253 (3):539-45
    View PubMed
  224. Jaspers K, Versluis B, Leiner T, Dijkstra P, Oostendorp M, van Golde JM, Post MJ, Backes WH. MR angiography of collateral arteries in a hind limb ischemia model: comparison between blood pool agent Gadomer and small contrast agent Gd-DTPA. PLoS One. 2011 Jan 26; 6 (1):e16159
    View PubMed
  225. Versluis B, Backes WH, van Eupen MG, Jaspers K, Nelemans PJ, Rouwet EV, Teijink JA, Mali WP, Schurink GW, Wildberger JE, Leiner T. Magnetic resonance imaging in peripheral arterial disease: reproducibility of the assessment of morphological and functional vascular status. Invest Radiol. 2011 Jan; 46 (1):11-24
    View PubMed
  226. Wang J, Gerretsen SC, Maki JH, Jaarsma C, Kooi ME, Herzka D, Chu B, Yarnykh VL, Yuan C, Leiner T. Time-efficient black blood RCA wall imaging at 3T using improved motion sensitized driven equilibrium (iMSDE): feasibility and reproducibility. PLoS One. 2011; 6 (10):e26567 Epub 2011 Oct 20
    View PubMed
  227. Bekkers SC, Smulders MW, Passos VL, Leiner T, Waltenberger J, Gorgels AP, Schalla S. Clinical implications of microvascular obstruction and intramyocardial haemorrhage in acute myocardial infarction using cardiovascular magnetic resonance imaging. Eur Radiol. 2010 Nov; 20 (11):2572-8 Epub 2010 June 26
    View PubMed
  228. Jaspers K, Leiner T, Dijkstra P, Oostendorp M, van Golde JM, Post MJ, Backes WH. Optimized pharmacokinetic modeling for the detection of perfusion differences in skeletal muscle with DCE-MRI: effect of contrast agent size. Med Phys. 2010 Nov; 37 (11):5746-55
    View PubMed
  229. Gerretsen SC, Kooi ME, Kessels AG, Schalla S, Katoh M, van der Geest RJ, Manning WJ, Waltenberger J, van Engelshoven JM, Botnar RM, Leiner T. Visualization of coronary wall atherosclerosis in asymptomatic subjects and patients with coronary artery disease using magnetic resonance imaging. PLoS One. 2010 Sep 29; 5 (9) Epub 2010 Sept 29
    View PubMed
  230. Rennenberg RJ, van Varik BJ, Schurgers LJ, Hamulyak K, Ten Cate H, Leiner T, Vermeer C, de Leeuw PW, Kroon AA. Chronic coumarin treatment is associated with increased extracoronary arterial calcification in humans. Blood. 2010 Jun 17; 115 (24):5121-3 Epub 2010 Mar 30
    View PubMed
  231. Laufer EM, Mingels AM, Winkens MH, Joosen IA, Schellings MW, Leiner T, Wildberger JE, Narula J, Van Dieijen-Visser MP, Hofstra L. The extent of coronary atherosclerosis is associated with increasing circulating levels of high sensitive cardiac troponin T. Arterioscler Thromb Vasc Biol. 2010 Jun; 30 (6):1269-75 Epub 2010 Mar 18
    View PubMed
  232. Gerretsen SC, le Maire TF, Miller S, Thurnher SA, Herborn CU, Michaely HJ, Kramer H, Vanzulli A, Vymazal J, Wasser MN, Ballarati CE, Kirchin MA, Pirovano G, Leiner T. Multicenter, double-blind, randomized, intraindividual crossover comparison of gadobenate dimeglumine and gadopentetate dimeglumine for MR angiography of peripheral arteries. Radiology. 2010 Jun; 255 (3):988-1000
    View PubMed
  233. Lobbes MB, Heeneman S, Passos VL, Welten R, Kwee RM, van der Geest RJ, Wiethoff AJ, Caravan P, Misselwitz B, Daemen MJ, van Engelshoven JM, Leiner T, Kooi ME. Gadofosveset-enhanced magnetic resonance imaging of human carotid atherosclerotic plaques: a proof-of-concept study. Invest Radiol. 2010 May; 45 (5):275-81
    View PubMed
  234. Schalla S, Bekkers SC, Dennert R, van Suylen RJ, Waltenberger J, Leiner T, Wildberger J, Crijns HJ, Heymans S. Replacement and reactive myocardial fibrosis in idiopathic dilated cardiomyopathy: comparison of magnetic resonance imaging with right ventricular biopsy. Eur J Heart Fail. 2010 Mar; 12 (3):227-31
    View PubMed
  235. Attenberger UI, Sourbron SP, Schoenberg SO, Morelli J, Leiner T, Schoeppler GM, Samtleben W, Birkemeier KL, Glaser C, Reiser MF, Michaely HJ. Comprehensive MR evaluation of renal disease: added clinical value of quantified renal perfusion values over single MR angiography. J Magn Reson Imaging. 2010 Jan; 31 (1):125-33
    View PubMed
  236. Prince MR, Zhang HL, Roditi GH, Leiner T, Kucharczyk W. Risk factors for NSF: a literature review. J Magn Reson Imaging. 2009 Dec; 30 (6):1298-308
    View PubMed
  237. Leiner T, Kucharczyk W. NSF prevention in clinical practice: summary of recommendations and guidelines in the United States, Canada, and Europe. J Magn Reson Imaging. 2009 Dec; 30 (6):1357-63
    View PubMed
  238. Maki JH, Wang M, Wilson GJ, Shutske MG, Leiner T. Highly accelerated first-pass contrast-enhanced magnetic resonance angiography of the peripheral vasculature: comparison of gadofosveset trisodium with gadopentetate dimeglumine contrast agents. J Magn Reson Imaging. 2009 Nov; 30 (5):1085-92
    View PubMed
  239. Jaspers K, Aerts HJ, Leiner T, Oostendorp M, van Riel NA, Post MJ, Backes WH. Reliability of pharmacokinetic parameters: small vs. medium-sized contrast agents. Magn Reson Med. 2009 Sep; 62 (3):779-87
    View PubMed
  240. Lobbes MB, Miserus RJ, Heeneman S, Passos VL, Mutsaers PH, Debernardi N, Misselwitz B, Post M, Daemen MJ, van Engelshoven JM, Leiner T, Kooi ME. Atherosclerosis: contrast-enhanced MR imaging of vessel wall in rabbit model--comparison of gadofosveset and gadopentetate dimeglumine. Radiology. 2009 Mar; 250 (3):682-91
    View PubMed
  241. Leiner T, Michaely H. Advances in contrast-enhanced MR angiography of the renal arteries. Magn Reson Imaging Clin N Am. 2008 Nov; 16 (4):561-72, vii
    View PubMed
  242. Cappendijk VC, Heeneman S, Kessels AG, Cleutjens KB, Schurink GW, Welten RJ, Mess WH, van Suylen RJ, Leiner T, Daemen MJ, van Engelshoven JM, Kooi ME. Comparison of single-sequence T1w TFE MRI with multisequence MRI for the quantification of lipid-rich necrotic core in atherosclerotic plaque. J Magn Reson Imaging. 2008 Jun; 27 (6):1347-55
    View PubMed
  243. Cappendijk VC, Kessels AG, Heeneman S, Cleutjens KB, Schurink GW, Welten RJ, Mess WH, van Suylen RJ, Leiner T, Daemen MJ, van Engelshoven JM, Kooi ME. Comparison of lipid-rich necrotic core size in symptomatic and asymptomatic carotid atherosclerotic plaque: Initial results. J Magn Reson Imaging. 2008 Jun; 27 (6):1356-61
    View PubMed
  244. Planken NR, Tordoir JH, Duijm LE, van den Bosch HC, van der Sande FM, Kooman JP, de Haan MW, Leiner T. Magnetic resonance angiographic assessment of upper extremity vessels prior to vascular access surgery: feasibility and accuracy. Eur Radiol. 2008 Jan; 18 (1):158-67 Epub 2007 July 24
    View PubMed
  245. Gerretsen SC, Versluis B, Bekkers SC, Leiner T. Cardiac cine MRI: comparison of 1.5 T, non-enhanced 3.0 T and blood pool enhanced 3.0 T imaging. Eur J Radiol. 2008 Jan; 65 (1):80-5 Epub 2007 Dec 26
    View PubMed
  246. Planken RN, Tordoir JH, Duijm LE, de Haan MW, Leiner T. Current techniques for assessment of upper extremity vasculature prior to hemodialysis vascular access creation. Eur Radiol. 2007 Nov; 17 (11):3001-11 Epub 2007 May 08
    View PubMed
  247. Planken RN, Duijm LE, Kessels AG, Leiner T, Kooman JP, Van Der Sande FM, Tordoir JH. Accessory veins and radial-cephalic arteriovenous fistula non-maturation: a prospective analysis using contrast-enhanced magnetic resonance angiography. J Vasc Access. 2007 Oct-Dec; 8 (4):281-6
    View PubMed
  248. Wang MS, Haynor DR, Wilson GJ, Leiner T, Maki JH. Maximizing contrast-to-noise ratio in ultra-high resolution peripheral MR angiography using a blood pool agent and parallel imaging. J Magn Reson Imaging. 2007 Sep; 26 (3):580-8
    View PubMed
  249. Gerretsen SC, Kooi ME, Schalla S, Delhaas T, Snoep G, Van Engelshoven JM, Leiner T. Magnetic resonance imaging of the coronary arteries. Cardiovasc J Afr. 2007 Jul-Aug; 18 (4):248-59
    View PubMed
  250. Hommels MJ, Kroon AA, Netea MG, de Leeuw PW, Bruggeman CA, Leiner T, Koster DA, Stalenhoef AF, van der Ven AJ. The Asp299Gly Toll-like receptor 4 polymorphism in advanced aortic atherosclerosis. Neth J Med. 2007 Jun; 65 (6):203-7
    View PubMed
  251. Nijenhuis RJ, Jacobs MJ, Jaspers K, Reinders M, van Engelshoven JM, Leiner T, Backes WH. Comparison of magnetic resonance with computed tomography angiography for preoperative localization of the Adamkiewicz artery in thoracoabdominal aortic aneurysm patients. J Vasc Surg. 2007 Apr; 45 (4):677-85 Epub 2007 Feb 15
    View PubMed
  252. Leiner T, Schoenberg SO. Current status of renal artery magnetic resonance imaging: theoretical and practical considerations and the potential role of blood-pool contrast agents. Eur Radiol. 2007 Mar; 17 Suppl 2:B13-7
    View PubMed
  253. Planken RN, Keuter XH, Kessels AG, Hoeks AP, Leiner T, Tordoir JH. Forearm cephalic vein cross-sectional area changes at incremental congestion pressures: towards a standardized and reproducible vein mapping protocol. J Vasc Surg. 2006 Aug; 44 (2):353-8
    View PubMed
  254. Bekkers SC, Leiner T. Images in cardiovascular medicine. Myocardial bridging. Circulation. 2006 Mar 7; 113 (9):e390-1
    View PubMed
  255. Planken RN, Keuter XH, Hoeks AP, Kooman JP, van der Sande FM, Kessels AG, Leiner T, Tordoir JH. Diameter measurements of the forearm cephalic vein prior to vascular access creation in end-stage renal disease patients: graduated pressure cuff versus tourniquet vessel dilatation. Nephrol Dial Transplant. 2006 Mar; 21 (3):802-6 Epub 2005 Dec 19
    View PubMed
  256. Prakken FJ, Kitslaar PJ, van de Kar N, Robben SF, Leiner T. Diagnosis of abdominal aortic hypoplasia by state-of-the-art MR angiography. Pediatr Radiol. 2006 Jan; 36 (1):57-60 Epub 2005 Nov 15
    View PubMed
  257. Leiner T, de Haan MW, Nelemans PJ, van Engelshoven JM, Vasbinder GB. Contemporary imaging techniques for the diagnosis of renal artery stenosis. Eur Radiol. 2005 Nov; 15 (11):2219-29 Epub 2005 June 28
    View PubMed
  258. Leiner T, Katsimaglis G, Yeh EN, Kissinger KV, van Yperen G, Eggers H, Manning WJ, Botnar RM. Correction for heart rate variability improves coronary magnetic resonance angiography. J Magn Reson Imaging. 2005 Oct; 22 (4):577-82
    View PubMed
  259. de Vries M, de Koning PJ, de Haan MW, Kessels AG, Nelemans PJ, Nijenhuis RJ, Planken RN, Vasbinder GB, van Engelshoven JM, van der Geest RJ, Leiner T. Accuracy of semiautomated analysis of 3D contrast-enhanced magnetic resonance angiography for detection and quantification of aortoiliac stenoses. Invest Radiol. 2005 Aug; 40 (8):495-503
    View PubMed
  260. Nijenhuis RJ, Gerretsen S, Leiner T, Jacobs MJ, van Engelshoven JM, Backes WH. Comparison of 0.5-M Gd-DTPA with 1.0-M gadobutrol for magnetic resonance angiography of the supplying arteries of the spinal cord in thoracoabdominal aortic aneurysm patients. J Magn Reson Imaging. 2005 Jul; 22 (1):136-44
    View PubMed
  261. Yeh EN, Stuber M, McKenzie CA, Botnar RM, Leiner T, Ohliger MA, Grant AK, Willig-Onwuachi JD, Sodickson DK. Inherently self-calibrating non-Cartesian parallel imaging. Magn Reson Med. 2005 Jul; 54 (1):1-8
    View PubMed
  262. Leiner T, Gerretsen S, Botnar R, Lutgens E, Cappendijk V, Kooi E, van Engelshoven J. Magnetic resonance imaging of atherosclerosis. Eur Radiol. 2005 Jun; 15 (6):1087-99 Epub 2005 Feb 19
    View PubMed
  263. Leiner T, Kessels AG, Nelemans PJ, Vasbinder GB, de Haan MW, Kitslaar PE, Ho KY, Tordoir JH, van Engelshoven JM. Peripheral arterial disease: comparison of color duplex US and contrast-enhanced MR angiography for diagnosis. Radiology. 2005 May; 235 (2):699-708
    View PubMed
  264. Leiner T. Magnetic resonance angiography of abdominal and lower extremity vasculature. Top Magn Reson Imaging. 2005 Feb; 16 (1):21-66
    View PubMed
  265. de Vries M, Nijenhuis RJ, Hoogeveen RM, de Haan MW, van Engelshoven JM, Leiner T. Contrast-enhanced peripheral MR angiography using SENSE in multiple stations: feasibility study. J Magn Reson Imaging. 2005 Jan; 21 (1):37-45
    View PubMed
  266. Vasbinder GB, Nelemans PJ, Kessels AG, Kroon AA, Maki JH, Leiner T, Beek FJ, Korst MB, Flobbe K, de Haan MW, van Zwam WH, Postma CT, Hunink MG, de Leeuw PW, van Engelshoven JM, Renal Artery Diagnostic Imaging Study in Hypertension (RADISH) Study Group. Accuracy of computed tomographic angiography and magnetic resonance angiography for diagnosing renal artery stenosis. Ann Intern Med. 2004 Nov 2; 141 (9):674-82; discussion 682
    View PubMed
  267. Nijenhuis RJ, Leiner T, Cornips EM, Wilmink JT, Jacobs MJ, van Engelshoven JM, Backes WH. Spinal cord feeding arteries at MR angiography for thoracoscopic spinal surgery: feasibility study and implications for surgical approach. Radiology. 2004 Nov; 233 (2):541-7 Epub 2004 Sept 09
    View PubMed
  268. Leiner T, Nijenhuis RJ, Maki JH, Lemaire E, Hoogeveen R, van Engelshoven JM. Use of a three-station phased array coil to improve peripheral contrast-enhanced magnetic resonance angiography. J Magn Reson Imaging. 2004 Sep; 20 (3):417-25
    View PubMed
  269. Leiner T, Kessels AG, Schurink GW, Kitslaar PJ, de Haan MW, Tordoir JH, van Engelshoven JM. Comparison of contrast-enhanced magnetic resonance angiography and digital subtraction angiography in patients with chronic critical ischemia and tissue loss. Invest Radiol. 2004 Jul; 39 (7):435-44
    View PubMed
  270. Visser K, Bosch JL, Leiner T, van Engelshoven Jm JM, Passchier J, Hunink MG. Patients' preferences for MR angiography and duplex US in the work-up of peripheral arterial disease. Eur J Vasc Endovasc Surg. 2003 Nov; 26 (5):537-43
    View PubMed
  271. Balzer JO, Loewe C, Davis K, Goyen M, Leiner T, Meaney JF, Pockler-Schoniger C, Schulte-Altedorneburg G, Tombach B, Vosshenrich R, Wegener R. Safety of contrast-enhanced MR angiography employing gadobutrol 1.0 M as contrast material. Eur Radiol. 2003 Sep; 13 (9):2067-74 Epub 2002 Dec 03
    View PubMed
  272. Hentsch A, Aschauer MA, Balzer JO, Brossmann J, Busch HP, Davis K, Douek P, Ebner F, van Engelshoven JM, Gregor M, Kersting C, Knusel PR, Leen E, Leiner T, Loewe C, McPherson S, Reimer P, Schafer FK, Taupitz M, Thurnher SA, Tombach B, Wegener R, Weishaupt D, Meaney JF. Gadobutrol-enhanced moving-table magnetic resonance angiography in patients with peripheral vascular disease: a prospective, multi-centre blinded comparison with digital subtraction angiography. Eur Radiol. 2003 Sep; 13 (9):2103-14 Epub 2003 Mar 25
    View PubMed
  273. Leiner T, Ho KY, Ho VB, Bongartz G, Mali WP, Rasch W, van Engelshoven JM. Multicenter phase-II trial of safety and efficacy of NC100150 for steady-state contrast-enhanced peripheral magnetic resonance angiography. Eur Radiol. 2003 Jul; 13 (7):1620-7 Epub 2003 Jan 18
    View PubMed
  274. Leiner T, Tordoir JH, Kessels AG, Nelemans PJ, Schurink GW, Kitslaar PJ, Ho KY, van Engelshoven JM. Comparison of treatment plans for peripheral arterial disease made with multi-station contrast medium-enhanced magnetic resonance angiography and duplex ultrasound scanning. J Vasc Surg. 2003 Jun; 37 (6):1255-62
    View PubMed
  275. Leiner T, de Vries M, Hoogeveen R, Vasbinder GB, Lemaire E, van Engelshoven JM. Contrast-enhanced peripheral MR angiography at 3.0 Tesla: initial experience with a whole-body scanner in healthy volunteers. J Magn Reson Imaging. 2003 May; 17 (5):609-14
    View PubMed
  276. Planken RN, Tordoir JH, Dammers R, de Haan MW, Oei TK, van der Sande FM, van Engelshoven JM, Leiner T. Stenosis detection in forearm hemodialysis arteriovenous fistulae by multiphase contrast-enhanced magnetic resonance angiography: preliminary experience. J Magn Reson Imaging. 2003 Jan; 17 (1):54-64
    View PubMed
  277. Vasbinder GB, Maki JH, Nijenhuis RJ, Leiner T, Wilson GJ, Kessels AG, Lemaire EE, Kaandorp DW, Ho KY, van Engelshoven JM. Motion of the distal renal artery during three-dimensional contrast-enhanced breath-hold MRA. J Magn Reson Imaging. 2002 Dec; 16 (6):685-96
    View PubMed
  278. Develing L, Leiner T, Kitslaar PJ. Magnetic resonance angiography for postnephrectomy arteriovenous fistula. Eur J Vasc Endovasc Surg. 2002 Feb; 23 (2):178-9
    View PubMed
  279. Pearlman JD, Laham RJ, Post M, Leiner T, Simons M. Medical imaging techniques in the evaluation of strategies for therapeutic angiogenesis. Curr Pharm Des. 2002; 8 (16):1467-96
    View PubMed
  280. Nelemans PJ, Leiner T, de Vet HC, van Engelshoven JM. Peripheral arterial disease: meta-analysis of the diagnostic performance of MR angiography. Radiology. 2000 Oct; 217 (1):105-14
    View PubMed
  281. Leiner T, Ho KY, Nelemans PJ, de Haan MW, van Engelshoven JM. Three-dimensional contrast-enhanced moving-bed infusion-tracking (MoBI-track) peripheral MR angiography with flexible choice of imaging parameters for each field of view. J Magn Reson Imaging. 2000 Apr; 11 (4):368-77
    View PubMed
  282. Ho KY, Leiner T, van Engelshoven JM. MR angiography of run-off vessels. Eur Radiol. 1999; 9 (7):1285-9
    View PubMed
  283. Ho KY, Leiner T, de Haan MW, van Engelshoven JM. Peripheral MR angiography. Eur Radiol. 1999; 9 (9):1765-74
    View PubMed
  284. Ho KY, Leiner T, de Haan MW, Kessels AG, Kitslaar PJ, van Engelshoven JM. Peripheral vascular tree stenoses: evaluation with moving-bed infusion-tracking MR angiography. Radiology. 1998 Mar; 206 (3):683-92
    View PubMed