颅咽管瘤

颅咽管瘤是一种罕见类型的非癌症脑肿瘤。

颅咽管瘤始于脑垂体附近的细胞生长物。脑垂体产生控制许多身体功能的激素。随着颅咽管瘤的缓慢生长,将影响脑垂体和大脑中的其他附近结构。

颅咽管瘤可发生于任何年龄,但最常见于儿童和老年人。症状包括视力随时间的变化、疲劳、头痛和排尿频率增加。患有颅咽管瘤的儿童可能成长缓慢,并且可能比预期更娇小。

症状

Signs and symptoms of craniopharyngioma may include:

  • Headaches.
  • Vision changes.
  • Nausea and vomiting.
  • Increased urination.
  • Sleepiness.
  • Memory troubles.
  • Loss of balance.
  • Trouble walking.
  • Changes in personality or behavior.
  • Weight gain and slowed growth in children.

When to see a doctor

Make an appointment with a doctor or other healthcare professional if you have any symptoms that worry you.

病因

It's not clear what causes craniopharyngioma. Craniopharyngioma begins as a growth of cells near the brain's pituitary gland. The pituitary gland makes hormones that control many body functions.

Craniopharyngioma happens when cells develop changes in their DNA. A cell's DNA holds the instructions that tell the cell what to do. In healthy cells, the DNA gives instructions to grow and multiply at a set rate. The instructions tell the cells to die at a set time. In tumor cells, the DNA changes give different instructions. The changes tell the tumor cells to grow and multiply quickly. Tumor cells can keep living when healthy cells would die. This causes too many cells.

风险因素

Healthcare professionals haven't found many risk factors for craniopharyngioma. This tumor can happen at any age. But it's more common in children and older adults.

Dec. 19, 2024

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  1. Ferri FF. Craniopharyngioma. In: Ferri's Clinical Advisor 2023. Elsevier; 2023. https://www.clinicalkey.com. Accessed April 28, 2023.
  2. Harsh GR, et al. Craniopharyngioma. https://www.uptodate.com/home. Accessed April 28, 2023.
  3. Childhood craniopharyngioma treatment (PDQ) – Patient version. National Cancer Institute. https://www.cancer.gov/types/brain/patient/child-cranio-treatment-pdq. Accessed April 28, 2023.
  4. Winn HR, ed. Pediatric craniopharyngiomas. In: Youmans and Winn Neurological Surgery. 8th ed. Elsevier; 2023. https://www.clinicalkey.com. Accessed April 28, 2023.
  5. Craniopharyngioma. Cancer.Net. https://www.cancer.net/cancer-types/craniopharyngioma-childhood/view-all. Accessed April 28, 2023.