Overview

Craniopharyngioma is a rare type of noncancerous brain tumor.

Craniopharyngioma begins as a growth of cells near the brain's pituitary gland. The pituitary gland makes hormones that control many body functions. As a craniopharyngioma slowly grows, it can affect the pituitary gland and other nearby structures in the brain.

Craniopharyngioma can happen at any age, but it occurs most often in children and older adults. Symptoms include changes in vision over time, fatigue, headaches and urinating more often. Children with craniopharyngioma may grow slowly and may be smaller than expected.

Symptoms

Signs and symptoms of craniopharyngioma may include:

  • Headaches.
  • Vision changes.
  • Nausea and vomiting.
  • Increased urination.
  • Sleepiness.
  • Memory troubles.
  • Loss of balance.
  • Trouble walking.
  • Changes in personality or behavior.
  • Weight gain and slowed growth in children.

When to see a doctor

Make an appointment with a doctor or other healthcare professional if you have any symptoms that worry you.

Causes

It's not clear what causes craniopharyngioma. Craniopharyngioma begins as a growth of cells near the brain's pituitary gland. The pituitary gland makes hormones that control many body functions.

Craniopharyngioma happens when cells develop changes in their DNA. A cell's DNA holds the instructions that tell the cell what to do. In healthy cells, the DNA gives instructions to grow and multiply at a set rate. The instructions tell the cells to die at a set time. In tumor cells, the DNA changes give different instructions. The changes tell the tumor cells to grow and multiply quickly. Tumor cells can keep living when healthy cells would die. This causes too many cells.

Risk factors

Healthcare professionals haven't found many risk factors for craniopharyngioma. This tumor can happen at any age. But it's more common in children and older adults.

April 12, 2025

Living with craniopharyngioma?

Connect with others like you for support and answers to your questions in the Brain Tumor support group on Mayo Clinic Connect, a patient community.

Brain Tumor Discussions

pixie49247
Meningioma: Anyone else? I'm frightened

393 Replies Wed, Apr 09, 2025

robinem
Watching a Meningioma Brain Tumor

287 Replies Tue, Apr 08, 2025

Tracy Lynne Daley
Anyone else diagnosed with acoustic neuroma, a benign brain tumor?

538 Replies Wed, Apr 02, 2025

See more discussions
  1. Ferri FF. Craniopharyngioma. In: Ferri's Clinical Advisor 2023. Elsevier; 2023. https://www.clinicalkey.com. Accessed April 28, 2023.
  2. Harsh GR, et al. Craniopharyngioma. https://www.uptodate.com/home. Accessed April 28, 2023.
  3. Childhood craniopharyngioma treatment (PDQ) – Patient version. National Cancer Institute. https://www.cancer.gov/types/brain/patient/child-cranio-treatment-pdq. Accessed April 28, 2023.
  4. Winn HR, ed. Pediatric craniopharyngiomas. In: Youmans and Winn Neurological Surgery. 8th ed. Elsevier; 2023. https://www.clinicalkey.com. Accessed April 28, 2023.
  5. Craniopharyngioma. Cancer.Net. https://www.cancer.net/cancer-types/craniopharyngioma-childhood/view-all. Accessed April 28, 2023.