Print ResearchDoctors and surgeons trained in nervous system conditions, also known as neurologists and neurosurgeons, are working to improve care for people who need a craniotomy. Researchers for the Brain Tumor Program study better ways to diagnose and treat all brain tumors. One area of study includes developing brain-mapping techniques for hard-to-reach tumors. Some areas studied by Mayo Clinic researchers include: The potential advantages of different types of craniotomies, including pterional keyhole craniotomy and supraorbital keyhole craniotomy. Techniques used in awake brain mapping for better outcomes after a craniotomy. The safety and potential risks of a craniotomy, along with the risk of delaying the procedure. PublicationsSee a list of publications about craniotomy by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine. By Mayo Clinic Staff Craniotomy care at Mayo Clinic Request an appointment AboutCare at Mayo Clinic Sept. 10, 2024 Print Show references Craniotomy. National Cancer Institute. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/craniotomy. Accessed May 22, 2024. Treatments and side effects. American Brain Tumor Association. https://www.abta.org/about-brain-tumors/treatments-side-effects/. Accessed May 22, 2024. Surgery for adult brain and spinal cord tumors. American Cancer Society. https://www.cancer.org/cancer/types/brain-spinal-cord-tumors-adults/treating/surgery.html. Accessed May 22, 2024. Living as a brain or spinal cord tumor survivor. American Cancer Society. https://www.cancer.org/cancer/types/brain-spinal-cord-tumors-adults/after-treatment/follow-up.html. Accessed May 22, 2024. Vogelbaum MA, et al. Treatment for brain metastases: ASCO-SNO-ASTRO guideline. Journal of Clinical Oncology. 2022; doi:10.1200/JCO.21.02314. Brain cancer: Glioma. National Comprehensive Cancer Network. https://www.nccn.org/guidelines/guidelines-detail?category=patients&id=5. Accessed May 22, 2024. Rao D, et al. An illustrative review of common modern craniotomies. Journal of Clinical Imaging Sciences. 2020; doi:10.25259/JCIS_176_2020. Ong V, et al. The pterional keyhole craniotomy approach: A historical perspective. World Neurosurgery. 2023; doi:10.1016/j.wneu.2023.07.012. Florez-Perdomo WA, et al. Supraorbital vs pterional keyhole for anterior circulation aneurysms: A systematic review and meta-analysis. World Neurosurgery: X. 2023; doi:10.1016/j.wnsx.2023.100177. Karadimas S, et al. Minimally invasive and outpatient aneurysm surgery: New concepts. Neurosurgery Clinics of North America. 2022; doi:10.1016/j.nec.2022.05.005. Robinow ZM, et al. Supraorbital keyhole craniotomy via eyebrow incision: A systematic review and meta-analysis. World Neurosurgery. 2022; doi:10.1016/j.wneu.2021.11.015. Xie T, et al. Endoscopic far-lateral supracerebellar infratentorial approach for petroclival region meningioma: Surgical technique and clinical experience. Operative Neurosurgery. 2022; doi:10.1227/ons.0000000000000126. Winn HR, ed. Awake craniotomy and intraoperative mapping. In: Youmans and Winn Neurological Surgery. 8th ed. Elsevier; 2023. https://www.clinicalkey.com. Accessed May 23, 2023. Quinones-Hinojosa A, et al., eds. Schmidek & Sweet: Operative Neurosurgical Techniques. 7th ed. Elsevier; 2022. https://www.clinicalkey.com. Accessed May 23, 2024. Strowd RE. Approach to a patient with brain metastasis. In: Neuro-Oncology for the Clinical Neurologist. Elsevier; 2021. https://www.clinicalkey.com. Accessed May 23, 2024. Jandial R. Core Techniques in Operative Neurosurgery. 2nd ed. Elsevier; 2020. https://www.clinicalkey.com. Accessed May 24, 2024. Functional MRI (fMRI). RadiologyInfo.org. https://www.radiologyinfo.org/en/info/fmribrain. Accessed May 24, 2024. Bertani R, et al. Minimally invasive craniotomies for lesions of the anterior and middle fossa. Neurosurgical Review. 2022; doi:10.1007/s10143-022-01850-z. Kulikov A, et al. Preoperative risk assessment before elective craniotomy: Are aspirin, arrhythmias, deep venous thromboses and hyperglycemia contraindications to surgery? World Neurosurgery. 2024; doi:10.1016/j.wneu.2024.03.018. Ekert JO, et al. Awake brain mapping paradigms for nondominant hemisphere gliomas. Neurosurgical Focus. 2024; doi:10.3171/2023.11.FOCUS23610. Perez-Vega C, et al. Safety and feasibility of a fast-track pathway for neurosurgical craniotomy patients: Bypassing the intensive care unit. Mayo Clinic Proceedings. 2023; doi:10.1016/j.mayocpiqo.2023.09.002. Marenco-Hillembrand L, et al. Unilateral supraorbital keyhole craniotomy avoiding the frontal sinus for large and giant olfactory-groove meningiomas: A case series. World Neurosurgery. 2023; doi:10.1016/j.wneu.2022.11.015. Nimmagadda R. Allscripts EPSi. Mayo Clinic. 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