Clinical Genomics

Angelman syndrome is a genetic disorder causing delays in development and neurological issues or symptoms. These may include problems with speech, balance and walking. In some cases, Angelman syndrome can be associated with seizures.

Angelman syndrome usually isn't recognized until a child shows delays in development (such as not crawling or babbling) between 6 to 12 months of age. Sometimes seizures begin between the ages of 2 and 3 years old. Treatment focuses on managing medical and developmental issues.

Because Angelman syndrome is a complex genetic disorder, it typically requires care from many different experts at all stages of life. Mayo Clinic's Angelman Syndrome Clinic gives you one place to go for a treatment plan. The clinic manages care and provides access to many specialists, depending on your or your child's needs, including:

• Gastroenterology.
• Genetics.
• Neurology, including neurodevelopmental assessment.
• Nutrition.
• Occupational Therapy.
• Orthopedics.
• Physical Medicine and Rehabilitation.
• Psychiatry and Psychology.
• Sleep medicine.
• Speech Pathology.

You and your child will meet with a team of experts at Mayo Clinic's Angelman Syndrome Clinic who create a personalized treatment plan. You may then take this plan home and work with your primary care providers to continue treatment.