Before Using
Drug information provided by: Merative, Micromedex®
In deciding to use a vaccine, the risks of taking the vaccine must be weighed against the good it will do. This is a decision you and your doctor will make. For this vaccine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of smallpox vaccine in children less than 16 years of age. Safety and efficacy have not been established .
Geriatric
No information is available on the relationship of age to the effects of smallpox vaccine in geriatric patients .
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Drug Interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this vaccine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Receiving this vaccine with any of the following medicines is not recommended. Your doctor may decide not to use this vaccine or change some of the other medicines you take.
Receiving this vaccine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
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Adalimumab
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Alemtuzumab
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Anifrolumab-fnia
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Ansuvimab-zykl
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Antithymocyte Globulin Rabbit
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Atidarsagene Autotemcel
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Atoltivimab
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Axicabtagene Ciloleucel
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Azathioprine
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Baricitinib
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Belatacept
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Bendamustine
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Betibeglogene Autotemcel
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Bimekizumab-bkzx
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Bortezomib
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Bosutinib
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Brexucabtagene Autoleucel
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Brodalumab
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Cabazitaxel
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Canakinumab
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Capecitabine
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Carboplatin
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Carfilzomib
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Carmustine
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Certolizumab Pegol
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Chlorambucil
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Cisplatin
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Cladribine
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Clofarabine
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Cyclophosphamide
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Cyclosporine
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Cytarabine
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Cytarabine Liposome
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Dacarbazine
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Dasatinib
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Daunorubicin
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Daunorubicin Citrate Liposome
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Daunorubicin Liposome
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Deucravacitinib
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Docetaxel
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Doxorubicin
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Dupilumab
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Efgartigimod Alfa-fcab
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Elivaldogene Autotemcel
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Emapalumab-lzsg
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Epirubicin
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Etanercept
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Etoposide
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Etrasimod
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Everolimus
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Fidanacogene Elaparvovec-dzkt
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Fingolimod
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Fludarabine
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Fluorouracil
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Gemcitabine
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Gemtuzumab Ozogamicin
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Golimumab
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Guselkumab
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Hyaluronidase
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Hydroxyurea
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Idarubicin
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Ifosfamide
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Imatinib
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Immune Globulin
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Inebilizumab-cdon
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Infliximab
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Interferon Alfa
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Irinotecan
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Irinotecan Liposome
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Ixekizumab
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Leflunomide
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Leniolisib
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Lomustine
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Lovotibeglogene Autotemcel
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Mechlorethamine
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Melphalan
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Mercaptopurine
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Methotrexate
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Mirikizumab-mrkz
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Mitomycin
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Mitoxantrone
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Mycophenolate Mofetil
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Mycophenolic Acid
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Nelarabine
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Nilotinib
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Ocrelizumab
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Ofatumumab
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Oxaliplatin
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Ozanimod
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Paclitaxel
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Paclitaxel Protein-Bound
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Pemetrexed
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Pentostatin
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Ponatinib
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Ponesimod
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Procarbazine
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Rilonacept
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Risankizumab-rzaa
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Ritlecitinib
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Rituximab
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Rozanolixizumab-noli
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Sarilumab
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Satralizumab-mwge
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Secukinumab
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Siponimod
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Sirolimus
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Spesolimab-sbzo
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Tacrolimus
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Temozolomide
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Teniposide
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Teplizumab-mzwv
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Teriflunomide
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Tildrakizumab-asmn
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Tocilizumab
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Tofacitinib
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Topotecan
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Tositumomab
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Trabectedin
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Tralokinumab-ldrm
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Ublituximab-xiiy
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Upadacitinib
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Ustekinumab
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Valoctocogene Roxaparvovec-rvox
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Vamorolone
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Vinblastine
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Vinorelbine
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Voclosporin
Receiving this vaccine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
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Abatacept
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Cytomegalovirus Immune Globulin, Human
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Hepatitis B Immune Globulin
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Rabies Immune Globulin
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Respiratory Syncytial Virus Immune Globulin, Human
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Tetanus Immune Globulin
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Vaccinia Immune Globulin, Human
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Varicella-Zoster Immune Globulin
Other Interactions
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this vaccine. Make sure you tell your doctor if you have any other medical problems, especially:
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Bone marrow transplant or
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Cancer or
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HIV or AIDS or
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Immune deficiency conditions or
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Leukemia (cancer of the blood) or
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Lymphoma (cancer of the lymph nodes)
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Organ transplant—Should not use in patients with these conditions .
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Burns, severe or
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Chest pain or
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Chickenpox or
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Congestive heart failure or
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Dermatitis or
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Diabetes or
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Eczema or
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Eye disease or
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Heart attack, history of or
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Heart disease (or family history of) or
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High blood pressure or
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High cholesterol in the blood or
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Impetigo or
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Psoriasis or
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Shingles or
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Stroke—May increase the chance and severity of side effects .
Portions of this document last updated: Aug. 01, 2024
Copyright: © Merative US L.P. 1973, 2024. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.