طب الجهاز الهضمي والكبد

بالأسفل التجارب السريرية الحالية.

غربل قائمة الدراسات هذه بالموقع والحالة وغيرها.

1. A Safety to Evaluate the Safety and Effectiveness of Pressurized Intraperitoneal Aerosolized Chemotherapy in Ovarian, Uterine, Colorectal, and Gastric Cancer Patients

   Jacksonville, Fla.

   The purpose of this study is to evaluate the safety of pressurized intraperitoneal aerosol chemotherapy (PIPAC) in 2 groups of patients with peritoneal carcinomatosis (PC), either due to primary ovarian, uterine, or gastric carcinoma (Arm 1) or to primary colorectal carcinoma (Arm 2), based on treatment-related adverse events reported by National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) version 5.0.  

2. Effect of Cholecystokinin (CCK) on Gastroduodenal Activity in Humans

   Rochester, Minn.

   The purpose of this research study to compare the effects a hormone cholecystokinin (CCK) in the bloodstream in healthy people and in patients with rapid gastric emptying. CCK regulates (controls) the rate at which food empties from the stomach into the small intestine. We want to learn how CCK affects the activity of the stomach and small intestines in patients with rapid gastric emptying. We are also trying to learn if genes regulate the effects of CCK.

3. A Study to Evaluate the Effects of Tradipitant on Satiation, Gastric Volume, Gastric Accommodation, and Gastric Emptying in Healthy Volunteers

   Rochester, Minn.

   The purpose of this study is to evaluate the effects of tradipitant relative to placebo in healthy volunteers:

   • Difference in fasting GV;
   • Difference in postprandial GV and in accommodation volume (that is, postprandial minus fasting gastric volumes);
   • Difference in gastric emptying (T1/2, emptying at 2h and emptying at 4h);
   • Volume to fullness (sensation of usual postprandial fullness) and maximum feeling of fullness (MTV).

4. A Study to Evaluate the Effectiveness of Diaphragmatic Breathing on Reflux Symptoms in Outpatients

   Jacksonville, Fla.

   The purpose of this study is to establish if abdominal breathing exercises can reduce symptoms associated with reflux.

5. A Study to Assess Intestinal Barrier Function and Permeability in Patients with Functional Dyspepsia

   Jacksonville, Fla.

   The purpose of this study is to investigate, using several novel techniques, potential pathophysiologic abnormalities that could lead to the development of symptoms of functional dyspepsia.

6. Mayo Clinic Inflammatory Bowel Disease Repository

   Rochester, Minn., Jacksonville, Fla., Scottsdale/Phoenix, Ariz.

   The purpose of this research study is to collect clinical information and human samples from patients with IBD. The data collected will be used to create an organized, accessible resource of human samples for biological research in IBD.

7. A Study of Intratumoral Injection of Dendritic Cells after High-Dose Conformal External Beam Radiotherapy in Patients with Unresectable Liver Cancer

   Rochester, Minn.

   Group 1: The primary purpose of this study is to evaluate the safety and tolerability of an autologous dendritic cells (DC) vaccine delivered by intra-tumoral injection in patients with primary liver cancer treated with high-dose conformal external beam radiotherapy (EBRT).

   Group 2: The primary purpose of this study is to estimate the progression-free survival rate at 2 years post-registration to see if treatment is efficacious compared to historical data

8. Symptoms During a Gastric Emptying Study

   Rochester, Minn.

   To understand the utility of measuring stomach emptying, symptoms during a stomach emptying, and blood markers of body metabolism.

9. A Study to Evaluate the Therapeutic Effectiveness of Rifaximin in Diabetic Gastroparesis Patients Using Bloating as the Primary Endpoint

   Jacksonville, Fla.

   The primary purpose of this study is to prospectively assess symptoms of bloating (severity, prevalence) in patients with diabetic gastroparesis.

10. Detection of Plasma DNA Methylation in Peripheral Blood from Patients with Hepatocellular Carcinoma

    Rochester, Minn.

    This study aims to investigate the utility of using plasma DNA methylation to detect measurable residual disease or early recurrence/progression of patients with hepatocellular carcinoma.