المنشورات طباعة Miller JJ, Augustin R, Sepiashvili L, Singh RJ, Bro E, Weishuhn K, Kotsopoulos K, Brennan J, Diambomba Y, Higgins V, Nichols M, Kulasingam V, Beriault DR, Yip PM, Taher J. Analytical Unreliability of 25 Hydroxy Vitamin D Measurements in Pre-Term Neonates. J Appl Lab Med. 2023 Sep 7; 8 (5):856-870 View PubMed Kanack AJ, Athale J, Leger RR, Saadalla A, Heikal NM, Chen D, Garcia DA, Singh R, Pruthi RK, Padmanabhan A. "Autoimmune HIT" antibodies in diagnostic samples are a potential artifact and not associated with more severe outcomes. Blood Adv. 2023 Aug 22; 7 (16):4431-4434 View PubMed Szabo Yamashita T, Mirande M, Huang CT, Kearns A, Fyffe-Freil R, Singh R, Foster T, Thompson G, Lyden M, McKenzie T, Wermers RA, Dy B. Persistence and Recurrence of Hypercalcemia After Parathyroidectomy Over 5 Decades (1965-2010) in a Community-based Cohort. Ann Surg. 2023 Aug 1; 278 (2):e309-e313 Epub 2022 Aug 26 View PubMed Ezra S, Winstone TML, Singh R, Orton DJ. Agreement of LC-MS assays for IGF-1 traceable to NIST and WHO standards permits harmonization of reference intervals between laboratories. Clin Biochem. 2023 Jun; 116:75-78 Epub 2023 Apr 07 View PubMed Colling C, Bredella MA, Fazeli PK, Pachon-Pena G, Singh RJ, Rosen CJ, Miller KK. Changes in serum cortisol levels after 10 days of overfeeding and fasting. Am J Physiol Endocrinol Metab. 2023 Jun 1; 324 (6):E506-E513 Epub 2023 Apr 13 View PubMed Maus A, Fatica EM, Taylor R, Larson BJ, Algeciras-Schimnich A, Singh RJ, Grebe SK. Identification, Measurement, and Assessment of the Clinical Utility of Human Pancreatic Polypeptide by Liquid Chromatography-Tandem Mass Spectrometry. J Proteome Res. 2023 Apr 7; 22 (4):1322-1330 Epub 2023 Mar 07 View PubMed Singh R, Valluri A, Didwania P, Lehrer EJ, Baliga S, Hiniker S, Braunstein SE, Murphy ES, Lazarev S, Tinkle C, Terezakis S, Palmer JD. Efficacy and Safety of Stereotactic Body Radiation Therapy for Pediatric Malignancies: The LITE-SABR Systematic Review and Meta-Analysis. Adv Radiat Oncol. 2023 Mar-Apr; 8 (2):101123 Epub 2023 Jan 05 View PubMed Lee JKY, Cradic K, Singh RJ, Jones J, Li J. Discordance of insulin-like growth factor-1 results and interpretation on four different platforms. Clin Chim Acta. 2023 Jan 15; 539:130-133 Epub 2022 Dec 14 View PubMed Egan AM, Galior KD, Maus AD, Fatica E, Simha V, Shah P, Singh RJ, Vella A. Pitfalls in Diagnosing Hypoglycemia Due to Exogenous Insulin: Validation and Utility of an Insulin Analog Assay. Mayo Clin Proc. 2022 Nov; 97(11):1994-2004. Epub 2022 Oct 07. View PubMed Mohammed-Ali Z, Delaney S, Singh R, Leung F, Taher J, Goguen J, Gilmour J, Sepiashvili L, Beriault DR. Bias in IGF-1 concentrations and interpretation across three different clinical laboratory assays. Clin Biochem. 2022 Oct; 108:14-19 Epub 2022 June 27 View PubMed Romaniuk M, Mahdi G, Singh R, Haglin J, Brown NJ, Gottfried O. Recent Trends in Medicare Utilization and Reimbursement for Spinal Cord Stimulators: 2000-2019. World Neurosurg. 2022 Oct; 166:e664-e671 Epub 2022 July 21 View PubMed Byeon SK, Madugundu AK, Garapati K, Ramarajan MG, Saraswat M, Kumar-M P, Hughes T, Shah R, Patnaik MM, Chia N, Ashrafzadeh-Kian S, Yao JD, Pritt BS, Cattaneo R, Salama ME, Zenka RM, Kipp BR, Grebe SKG, Singh RJ, Sadighi Akha AA, Algeciras-Schimnich A, Dasari S, Olson JE, Walsh JR, Venkatakrishnan AJ, Jenkinson G, O'Horo JC, Badley AD, Pandey A. Development of a multiomics model for identification of predictive biomarkers for COVID-19 severity: a retrospective cohort study. Lancet Digit Health. 2022 Sep; 4 (9):e632-e645 Epub 2022 July 11 View PubMed Vanderboom PM, Renuse S, Maus AD, Madugundu AK, Kemp JV, Gurtner KM, Singh RJ, Grebe SK, Pandey A, Dasari S. Machine Learning-Based Fragment Selection Improves the Performance of Qualitative PRM Assays. J Proteome Res. 2022 Aug 5; 21 (8):2045-2054 Epub 2022 July 18 View PubMed Ulmer CZ, Kritmetapak K, Singh RJ, Vesper HW, Kumar R. High-Resolution Mass Spectrometry for the Measurement of PTH and PTH Fragments: Insights into PTH Physiology and Bioactivity. J Am Soc Nephrol. 2022 Aug; 33 (8):1448-1458 Epub 2022 Apr 08 View PubMed Nardi V, Franchi F, Prasad M, Fatica EM, Alexander MP, Bois MC, Lam J, Singh RJ, Meyer FB, Lanzino G, Xiong Y, Lutgens E, Lerman LO, Lerman A. Uric Acid Expression in Carotid Atherosclerotic Plaque and Serum Uric Acid Are Associated With Cerebrovascular Events. Hypertension. 2022 Aug; 79 (8):1814-1823 Epub 2022 June 03 View PubMed Waldron RT, Jones EK, Anani VI, Hines JM, Zhao J, Lugea A, Diniz MA, Kim S, Habtezion A, Hoffman KL, Petrosino JF, Fisher WE, Li L, Lennon RJ, Singh RJ, Vege SS, Pandol SJ, Topazian MD. Salivary Biomarker Evaluation of Chronic Pancreatitis Patients Reveals Alterations in Human Proteins, Cytokines, Prostaglandin E2 Levels, and Bacterial Diversity. Pancreas. 2022 Aug 1; 51 (7):723-732 View PubMed Mangalaparthi KK, Chavan S, Madugundu AK, Renuse S, Vanderboom PM, Maus AD, Kemp J, Kipp BR, Grebe SK, Singh RJ, Pandey A. Correction: A SISCAPA-based approach for detection of SARS-CoV-2 viral antigens from clinical samples. Clin Proteomics. 2022 May 4; 19 (1):11 Epub 2022 May 04 View PubMed Oberhelman-Eaton S, Chang A, Gonzalez C, Braith A, Singh RJ, Lteif A. Initiation of Gender-Affirming Testosterone Therapy in a Lactating Transgender Man. J Hum Lact. 2022 May; 38 (2):339-343 Epub 2021 Sept 07 View PubMed Genere N, Kaur RJ, Athimulam S, Thomas MA, Nippoldt T, Van Norman M, Singh R, Grebe S, Bancos I. Interpretation of Abnormal Dexamethasone Suppression Test is Enhanced With Use of Synchronous Free Cortisol Assessment. J Clin Endocrinol Metab. 2022 Feb 17; 107 (3):e1221-e1230 View PubMed Maus A, Renuse S, Kemp J, Madugundu AK, Vanderboom PM, Blommel J, Jerde C, Dasari S, Kipp BR, Singh RJ, Grebe SK, Pandey A. Targeted Detection of SARS-CoV-2 Nucleocapsid Sequence Variants by Mass Spectrometric Analysis of Tryptic Peptides. J Proteome Res. 2022 Jan 7; 21 (1):142-150 Epub 2021 Nov 15 View PubMed Holtz LR, Hoffmann J, Linneman L, He M, Smyrk TC, Liu TC, Shaikh N, Rodriguez C, Dyer RB, Singh RJ, Faubion WA. Rhamnose Is Superior to Mannitol as a Monosaccharide in the Dual Sugar Absorption Test: A Prospective Randomized Study in Children With Treatment-Naive Celiac Disease. Front Pediatr. 2022; 10:874116 Epub 2022 Apr 07 View PubMed Upadhyay R, Yadav D, Venkatesulu BP, Singh R, Baliga S, Raval RR, Lazow MA, Salloum R, Fouladi M, Mardis ER, Zaorsky NG, Trifiletti DM, Paulino AC, Palmer JD. Risk of secondary malignant neoplasms in children following proton therapy vs. photon therapy for primary CNS tumors: A systematic review and meta-analysis. Front Oncol. 2022; 12:893855 Epub 2022 Aug 12 View PubMed Fatica EM, Larkey NE, Singh RJ. Quantification of Parathyroid Hormone and its Fragments in Serum by Liquid Chromatography-High-Resolution Mass Spectrometry. Methods Mol Biol. 2022; 2546:365-373 View PubMed Maus A, Renuse S, Kemp J, Moehnke K, Mangalaparthi KK, Chavan S, Madugundu AK, Vanderboom PM, Dasari S, Kipp BR, Singh RJ, Grebe SK, Pandey A. Comparison of anti-peptide and anti-protein antibody-based purification techniques for detection of SARS-CoV-2 by targeted LC-MS/MS. Advances in Sample Preparation. 2022; 2:100018 Fatica EM, Larkey NE, Singh RJ. Quantification of Insulin Analogs by Liquid Chromatography-High-Resolution Mass Spectrometry. Methods Mol Biol. 2022; 2546:217-226 View PubMed Larkey NE, Fatica EM, Singh RJ. Differentiation of Common IGF-1 Variants Using HRMS COM Determination with Follow-Up MS/MS Verification. Methods Mol Biol. 2022; 2546:227-237 View PubMed Larkey NE, Fatica EM, Singh RJ. Detection of 13C-Mannitol and Other Saccharides Using Tandem Mass Spectrometry for Evaluation of Intestinal Permeability or Leaky Gut. Methods Mol Biol. 2022; 2546:285-294 View PubMed Singh P, Covassin N, Sert-Kuniyoshi FH, Marlatt KL, Romero-Corral A, Davison DE, Singh RJ, Jensen MD, Somers VK. Overfeeding-induced weight gain elicits decreases in sex hormone-binding globulin in healthy males-Implications for body fat distribution. Physiol Rep. 2021 Dec; 9 (23):e15127 View PubMed Ulmer CZ, Maus A, Hines J, Singh R. Challenges in Translating Clinical Metabolomics Data Sets from the Bench to the Bedside. Clin Chem. 2021 Nov 26; 67 (12):1581-1583 View PubMed Verdoorn BP, Evans TK, Hanson GJ, Zhu Y, Langhi Prata LGP, Pignolo RJ, Atkinson EJ, Wissler-Gerdes EO, Kuchel GA, Mannick JB, Kritchevsky SB, Khosla S, Rizza SA, Walston JD, Musi N, Lipsitz LA, Kiel DP, Yung R, LeBrasseur NK, Singh RJ, McCarthy T, Puskarich MA, Niedernhofer LJ, Robbins PD, Sorenson M, Tchkonia T, Kirkland JL. Fisetin for COVID-19 in skilled nursing facilities: Senolytic trials in the COVID era. J Am Geriatr Soc. 2021 Nov; 69 (11):3023-3033 Epub 2021 Aug 20 View PubMed Vela S, Guerra A, Farrell G, Trivedi S, Chaffin H, Rood C, Singh R, Kostenko S, Chang YH, Snozek C, Patel K, Khatua B, Singh VP. Pathophysiology and Biomarker Potential of Fatty Acid Ethyl Ester Elevation During Alcoholic Pancreatitis. Gastroenterology. 2021 Nov; 161 (5):1513-1525 Epub 2021 July 23 View PubMed Karon BS, Donato LJ, Bridgeman AR, Blommel JH, Kipp B, Maus A, Renuse S, Kemp J, Madugundu AK, Vanderboom PM, Chavan S, Dasari S, Singh RJ, Grebe SK, Pandey A. Analytical Sensitivity and Specificity of Four Point of Care Rapid Antigen Diagnostic Tests for SARS-CoV-2 Using Real-Time Quantitative PCR, Quantitative Droplet Digital PCR, and a Mass Spectrometric Antigen Assay as Comparator Methods. Clin Chem. 2021 Nov 1; 67 (11):1545-1553 View PubMed Mangalaparthi KK, Chavan S, Madugundu AK, Renuse S, Vanderboom PM, Maus AD, Kemp J, Kipp BR, Grebe SK, Singh RJ, Pandey A. A SISCAPA-based approach for detection of SARS-CoV-2 viral antigens from clinical samples. Clin Proteomics 2021 Oct 22; 18 (1):25 View PubMed Kritmetapak K, Singh RJ, Craig TA, Hines JM, Kumar R. Short carboxyl terminal parathyroid hormone peptides modulate human parathyroid hormone signaling in mouse osteoblasts. Biochem Biophys Res Commun. 2021 Oct 1; 572:15-19 Epub 2021 July 28 View PubMed Bacha DS, Rahme M, Al-Shaar L, Baddoura R, Halaby G, Singh RJ, Mahfoud ZR, Habib R, Arabi A, El-Hajj Fuleihan G. Vitamin D3 Dose Requirement That Raises 25-Hydroxyvitamin D to Desirable Level in Overweight and Obese Elderly. J Clin Endocrinol Metab. 2021 Aug 18; 106 (9):e3644-e3654 View PubMed Khoshbin K, Khanna L, Maselli D, Atieh J, Breen-Lyles M, Arndt K, Rhoten D, Dyer RB, Singh RJ, Nayar S, Bjerkness S, Harmsen WS, Busciglio I, Camilleri M. Development and Validation of Test for "Leaky Gut" Small Intestinal and Colonic Permeability Using Sugars in Healthy Adults. Gastroenterology. 2021 Aug; 161 (2):463-475.e13 Epub 2021 Apr 16 View PubMed Butterfield JH, Singh RJ. Divergent PGD(2) and leukotriene C(4) metabolite excretion following aspirin therapy: Ten patients with systemic mastocytosis. Prostaglandins Other Lipid Mediat. 2021 Aug; 155:106563 Epub 2021 May 21 View PubMed Renuse S, Vanderboom PM, Maus AD, Kemp JV, Gurtner KM, Madugundu AK, Chavan S, Peterson JA, Madden BJ, Mangalaparthi KK, Mun DG, Singh S, Kipp BR, Dasari S, Singh RJ, Grebe SK, Pandey A. A mass spectrometry-based targeted assay for detection of SARS-CoV-2 antigen from clinical specimens. EBioMedicine. 2021 Jul; 69:103465 Epub 2021 July 03 View PubMed Huayllas MKP, Smith LM, Gallagher JC, Netzel BC, Singh RJ, Kater CE. Steroidogenesis in patients with adrenal incidentalomas: Extended steroid profile measured by liquid chromatography-mass spectrometry after ACTH stimulation and dexamethasone suppression. Clin Endocrinol (Oxf). 2021 Jul; 95 (1):29-40 Epub 2021 Mar 02 View PubMed Kritmetapak K, Losbanos LA, Hines JM, O'Grady KL, Ulmer CZ, Vesper HW, Enders FT, Singh RJ, Kumar R. Chemical Characterization and Quantification of Circulating Intact PTH and PTH Fragments by High-Resolution Mass Spectrometry in Chronic Renal Failure. Clin Chem. 2021 Jun 1; 67 (6):843-853 View PubMed Javorsky BR, Raff H, Carroll TB, Algeciras-Schimnich A, Singh RJ, Colon-Franco JM, Findling JW. New Cutoffs for the Biochemical Diagnosis of Adrenal Insufficiency after ACTH Stimulation using Specific Cortisol Assays. J Endocr Soc. 2021 Apr 1; 5 (4):bvab022 Epub 2021 Feb 18 View PubMed Singh AK, Cai C, Kilari S, Zhao C, Simeon ML, Takahashi E, Edelman ER, Kong HJ, Macedo T, Singh RJ, Urban MW, Kumar R, Misra S. 1alpha,25-Dihydroxyvitamin D(3) Encapsulated in Nanoparticles Prevents Venous Neointimal Hyperplasia and Stenosis in Porcine Arteriovenous Fistulas. J Am Soc Nephrol. 2021 Apr; 32 (4):866-885 Epub 2021 Feb 24 View PubMed Kritmetapak K, Losbanos L, Berent TE, Ashrafzadeh-Kian SL, Algeciras-Schimnich A, Hines JM, Singh RJ, Kumar R. Hyperphosphatemia with elevated serum PTH and FGF23, reduced 1,25(OH)2D and normal FGF7 concentrations characterize patients with CKD. BMC Nephrol. 2021 Mar 30; 22 (1):114 View PubMed Boggs ASP, Kilpatrick LE, Burdette CQ, Tevis DS, Fultz ZA, Nelson MA, Jarrett JM, Kemp JV, Singh RJ, Grebe SKG, Wise SA, Kassim BL, Long SE. Development of a pregnancy-specific reference material for thyroid biomarkers, vitamin D, and nutritional trace elements in serum. Clin Chem Lab Med. 2021 Mar 26; 59 (4):671-679 Epub 2020 Oct 26 View PubMed Al Khazal F, Kang S, Nelson Holte M, Choi DS, Singh R, Ortega-Saenz P, Lopez-Barneo J, Maher LJ 3rd. Unexpected obesity, rather than tumorigenesis, in a conditional mouse model of mitochondrial complex II deficiency. FASEB J. 2021 Feb; 35 (2):e21227 Epub 2020 Nov 27 View PubMed El Sabeh M, Ghanem P, Al-Shaar L, Rahme M, Baddoura R, Halaby G, Singh RJ, Vanderschueren D, Bouillon R, El-Hajj Fuleihan G. Total, Bioavailable, and Free 25(OH)D Relationship with Indices of Bone Health in Elderly: A Randomized Controlled Trial. J Clin Endocrinol Metab. 2021 Jan 23; 106 (2):e990-e1001 View PubMed Sharma S, Kumar P, Singh R, Sidhu GS, Shah K. Psychotic Symptoms in Heroin Withdrawal: A Case Report. Cureus. 2021 Jan 11; 13 (1):e12620 View PubMed Singh R, Rathore SS, Khan H, Bhurwal A, Sheraton M, Ghosh P, Anand S, Makadia J, Ayesha F, Mahapure KS, Mehra I, Tekin A, Kashyap R, Bansal V. Mortality and Severity in COVID-19 Patients on ACEIs and ARBs-A Systematic Review, Meta-Analysis, and Meta-Regression Analysis. Front Med (Lausanne). 2021; 8:703661 Epub 2022 Jan 10 View PubMed Bansal V, Mahapure KS, Mehra I, Bhurwal A, Tekin A, Singh R, Gupta I, Rathore SS, Khan H, Deshpande S, Gulati S, Armaly P, Sheraton M, Kashyap R. Mortality Benefit of Convalescent Plasma in COVID-19: A Systematic Review and Meta-Analysis. Front Med (Lausanne). 2021; 8:624924 Epub 2021 Apr 09 View PubMed Geno KA, Tolan NV, Singh RJ, Nerenz RD. Improved Recognition of 25-Hydroxyvitamin D2 by 2 Automated Immunoassays. J Appl Lab Med. 2020 Nov 1; 5 (6):1287-1295 View PubMed Dichtel LE, Carpenter LL, Nyer M, Mischoulon D, Kimball A, Deckersbach T, Dougherty DD, Schoenfeld DA, Fisher L, Cusin C, Dording C, Trinh NH, Pedrelli P, Yeung A, Farabaugh A, Papakostas GI, Chang T, Shapero BG, Chen J, Cassano P, Hahn EM, Rao EM, Brady RO Jr, Singh RJ, Tyrka AR, Price LH, Fava M, Miller KK. Low-Dose Testosterone Augmentation for Antidepressant-Resistant Major Depressive Disorder in Women: An 8-Week Randomized Placebo-Controlled Study. Am J Psychiatry. 2020 Oct 1; 177 (10):965-973 Epub 2020 July 14 View PubMed Singh R, Didwania P, Lehrer EJ, Sheehan D, Sheehan K, Trifiletti DM, Sheehan JP. Stereotactic radiosurgery for acromegaly: an international systematic review and meta-analysis of clinical outcomes. J Neurooncol. 2020 Jul; 148 (3):401-418 Epub 2020 June 06 View PubMed Ingle JN, Cairns J, Suman VJ, Shepherd LE, Fasching PA, Hoskin TL, Singh RJ, Desta Z, Kalari KR, Ellis MJ, Goss PE, Chen BE, Volz B, Barman P, Carlson EE, Haddad T, Goetz MP, Goodnature B, Cuellar ME, Walters MA, Correia C, Kaufmann SH, Weinshilboum RM, Wang L. Anastrozole has an Association between Degree of Estrogen Suppression and Outcomes in Early Breast Cancer and is a Ligand for Estrogen Receptor alpha. Clin Cancer Res. 2020 Jun 15; 26 (12):2986-2996 Epub 2020 Feb 25 View PubMed Kanike N, Groh-Wargo S, Thomas M, Chien EK, Mhanna M, Kumar D, Worley S, Singh RJ, Shekhawat PS. Risk of Iodine Deficiency in Extremely Low Gestational Age Newborns on Parenteral Nutrition. Nutrients. 2020 Jun 1; 12 (6) Epub 2020 June 01 View PubMed Richardson H, Ho V, Pasquet R, Singh RJ, Goetz MP, Tu D, Goss PE, Ingle JN, MAP.3 Investigators. Baseline estrogen levels in postmenopausal women participating in the MAP.3 breast cancer chemoprevention trial. Menopause. 2020 Jun; 27 (6):693-700 View PubMed Eckhardt BA, Rowsey JL, Thicke BS, Fraser DG, O'Grady KL, Bondar OP, Hines JM, Singh RJ, Thoreson AR, Rakshit K, Lagnado AB, Passos JF, Vella A, Matveyenko AV, Khosla S, Monroe DG, Farr JN. Accelerated osteocyte senescence and skeletal fragility in mice with type 2 diabetes. JCI Insight. 2020 May 7; 5 (9) Epub 2020 May 07 View PubMed O'Grady KL, Khosla S, Farr JN, Bondar OP, Atkinson EJ, Achenbach SJ, Eckhardt BA, Thicke BS, Tweed AJ, Volkman TL, Drake MT, Hines JM, Singh RJ. Development and Application of Mass Spectroscopy Assays for Nepsilon-(1-Carboxymethyl)-L-Lysine and Pentosidine in Renal Failure and Diabetes. J Appl Lab Med. 2020 May 1; 5 (3):558-568 View PubMed Olsen TW, Dyer RB, Mano F, Boatright JH, Chrenek MA, Paley D, Wabner K, Schmit J, Chae JB, Sellers JT, Singh RJ, Wiedmann TS. Drug Tissue Distribution of TUDCA From a Biodegradable Suprachoroidal Implant versus Intravitreal or Systemic Delivery in the Pig Model. Transl Vis Sci Technol. 2020 May; 9 (6):11 Epub 2020 May 15 View PubMed Kotwal A, Ferrer A, Kumar R, Singh RJ, Murthy V, Schultz-Rogers L, Zimmermann M, Lanpher B, Zimmerman K, Stabach PR, Klee E, Braddock DT, Wermers RA. Clinical and Biochemical Phenotypes in a Family With ENPP1 Mutations. J Bone Miner Res. 2020 Apr; 35 (4):662-670 Epub 2020 Jan 16 View PubMed Lu M, Hollis BW, Carey VJ, Laranjo N, Singh RJ, Weiss ST, Litonjua AA. Determinants and Measurement of Neonatal Vitamin D: Overestimation of 25(OH)D in Cord Blood Using CLIA Assay Technology. J Clin Endocrinol Metab. 2020 Apr 1; 105 (4) View PubMed Huayllas MKP, Sirineni GK, Smith LM, Gallagher JC, Singh RJ, Netzel BC, Kater CE. Correlation Between Size and Function of Unilateral and Bilateral Adrenocortical Nodules: An Observational Study. AJR Am J Roentgenol. 2020 Apr; 214 (4):800-807 Epub 2020 Feb 18 View PubMed Singh R, Lehrer EJ, Ko S, Peterson J, Lou Y, Porter AB, Kotecha R, Brown PD, Zaorsky NG, Trifiletti DM. Brain metastases from non-small cell lung cancer with EGFR or ALK mutations: A systematic review and meta-analysis of multidisciplinary approaches. Radiother Oncol. 2020 Mar; 144:165-179 Epub 2019 Dec 05 View PubMed Maus A, Kemp J, Milosevic D, Renuse S, Pandey A, Singh RJ, Grebe SKG. Center of Mass Calculation in Combination with MS/MS Allows Robust Identification of Single Amino Acid Polymorphisms in Clinical Measurements of Insulin-Like Growth Factor-1. J Proteome Res. 2020 Jan 3; 19 (1):186-193 Epub 2019 Dec 09 View PubMed Singh R, Stoltzfus KC, Chen H, Louie AV, Lehrer EJ, Horn SR, Palmer JD, Trifiletti DM, Brown PD, Zaorsky NG. Epidemiology of synchronous brain metastases. Neurooncol Adv. 2020 Jan-Dec; 2 (1):vdaa041 Epub 2020 Apr 24 View PubMed Flemming KD, Kumar S, Brown RD Jr, Singh RJ, Whitehead K, McCreath L, Lanzino G. Cavernous Malformation Hemorrhagic Presentation at Diagnosis Associated with Low 25-Hydroxy-Vitamin D Level. Cerebrovasc Dis. 2020; 49 (2):216-222 Epub 2020 Apr 29 View PubMed Khan MR, Faubion WA, Dyer R, Singh R, Larson JJ, Absah I. Role of Lactulose Rhamnose Permeability Test in Assessing Small Bowel Mucosal Damage in Children with Celiac Disease. Glob Pediatr Health. 2020; 7:2333794X20969278 Epub 2020 Nov 11 View PubMed Chen L, Singh RJ. Utilities of traditional and novel biomarkers in the management of acute kidney injury Critical Reviews in Clinical Laboratory Sciences. 2020; 57 (4):215-26 Roizen JD, Long C, Casella A, O'Lear L, Caplan I, Lai M, Sasson I, Singh R, Makowski AJ, Simmons R, Levine MA. Obesity Decreases Hepatic 25-Hydroxylase Activity Causing Low Serum 25-Hydroxyvitamin D. J Bone Miner Res. 2019 Jun; 34 (6):1068-1073 Epub 2019 Feb 21 View PubMed Khatua B, Trivedi RN, Noel P, Patel K, Singh R, de Oliveira C, Trivedi S, Mishra V, Lowe M, Singh VP. Carboxyl Ester Lipase May Not Mediate Lipotoxic Injury during Severe Acute Pancreatitis. Am J Pathol. 2019 Jun; 189 (6):1226-1240 Epub 2019 Apr 05 View PubMed Dodd SE, Singh RJ, Martin YN. Catecholamine and Metanephrine Levels in Breast Milk Before and After Paraganglioma Resection. Breastfeed Med. 2019 May; 14 (4):276-277 Epub 2019 Mar 15 View PubMed Kaur RJ, Pichurin PN, Hines JM, Singh RJ, Grebe SK, Bancos I. Adrenal Cortical Carcinoma Associated With Lynch Syndrome: A Case Report and Review of Literature. J Endocr Soc. 2019 Apr 1; 3 (4):784-790 Epub 2019 Mar 05 View PubMed Rahme M, Al-Shaar L, Singh R, Baddoura R, Halaby G, Arabi A, Habib RH, Daher R, Bassil D, El-Ferkh K, Hoteit M, El-Hajj Fuleihan G. Limitations of platform assays to measure serum 25OHD level impact on guidelines and practice decision making. Metabolism. 2018 Dec; 89:1-7 Epub 2018 Sept 15 View PubMed Sharma A, Kapoor E, Singh RJ, Chang AY, Erickson D. Diagnostic Thresholds for Androgen-Producing Tumors or Pathologic Hyperandrogenism in Women by Use of Total Testosterone Concentrations Measured by Liquid Chromatography-Tandem Mass Spectrometry. Clin Chem. 2018 Nov; 64 (11):1636-1645 Epub 2018 Aug 01 View PubMed Mok CC, Bro ET, Ho LY, Singh RJ, Jannetto PJ. Serum 25-hydroxyvitamin D3 levels and flares of systemic lupus erythematosus: a longitudinal cohort analysis. Clin Rheumatol. 2018 Oct; 37 (10):2685-2692 Epub 2018 July 16 View PubMed Jain VG, Goyal V, Chowdhary V, Swarup N, Singh RJ, Singal A, Shekhawat P. Anogenital distance is determined during early gestation in humans. Hum Reprod. 2018 Sep 1; 33 (9):1619-1627 View PubMed Kraus J, Unanue N, Espinoza A, Iniguez G, Torres-Santiago L, Singh R, Mauras N, Mericq V. Is There a Difference between Ultrasonographic (US) Uterine Changes of Oral Versus Transdermal (TD) 17beta Estradiol (17beta E2) in Girls with Turner Syndrome (TS)? Own Experience and Literature Review. Pediatr Endocrinol Rev. 2018 Sep; 16 (1):178-185 View PubMed Xu M, Pirtskhalava T, Farr JN, Weigand BM, Palmer AK, Weivoda MM, Inman CL, Ogrodnik MB, Hachfeld CM, Fraser DG, Onken JL, Johnson KO, Verzosa GC, Langhi LGP, Weigl M, Giorgadze N, LeBrasseur NK, Miller JD, Jurk D, Singh RJ, Allison DB, Ejima K, Hubbard GB, Ikeno Y, Cubro H, Garovic VD, Hou X, Weroha SJ, Robbins PD, Niedernhofer LJ, Khosla S, Tchkonia T, Kirkland JL. Senolytics improve physical function and increase lifespan in old age. Nat Med. 2018 Aug; 24(8):1246-1256. Epub 2018 Jul 09. View PubMed Galior K, Grebe S, Singh R. Development of Vitamin D Toxicity from Overcorrection of Vitamin D Deficiency: A Review of Case Reports. Nutrients. 2018 Jul 24; 10 (8) Epub 2018 July 24 View PubMed Huayllas MKP, Netzel BC, Singh RJ, Kater CE. Serum Cortisol Levels via Radioimmunoassay vs Liquid Chromatography Mass Spectrophotometry in Healthy Control Subjects and Patients With Adrenal Incidentalomas. Lab Med. 2018 Jul 5; 49 (3):259-267 View PubMed Edogawa S, Peters SA, Jenkins GD, Gurunathan SV, Sundt WJ, Johnson S, Lennon RJ, Dyer RB, Camilleri M, Kashyap PC, Farrugia G, Chen J, Singh RJ, Grover M. Sex differences in NSAID-induced perturbation of human intestinal barrier function and microbiota. FASEB J. 2018 Jun 13; 32 (12):fj201800560R Epub 2018 June 13 View PubMed Galior K, Ketha H, Grebe S, Singh RJ. 10 years of 25-hydroxyvitamin-D testing by LC-MS/MS-trends in vitamin-D deficiency and sufficiency. Bone Rep. 2018 Jun; 8:268-273 Epub 2018 May 23 View PubMed Singh RJ. Commentary. Clin Chem 2018 Jun; 64 (6):897 View PubMed Ketha H, Thacher TD, Oberhelman SS, Fischer PR, Singh RJ, Kumar R. Comparison of the effect of daily versus bolus dose maternal vitamin D3 supplementation on the 24,25-dihydroxyvitamin D3 to 25-hydroxyvitamin D3 ratio. Bone. 2018 May; 110:321-325 Epub 2018 Feb 24 View PubMed Chen LS, Singh RJ. Niche point-of-care endocrine testing - Reviews of intraoperative parathyroid hormone and cortisol monitoring. Crit Rev Clin Lab Sci. 2018 Mar; 55 (2):115-128 Epub 2018 Jan 22 View PubMed Akturk HK, Chindris AM, Hines JM, Singh RJ, Bernet VJ. Over-the-Counter "Adrenal Support" Supplements Contain Thyroid and Steroid-Based Adrenal Hormones. Mayo Clin Proc. 2018 Mar; 93 (3):284-290 View PubMed Hines JM, Bancos I, Bancos C, Singh RD, Avula AV, Young WF, Grebe SK, Singh RJ. High-Resolution, Accurate-Mass (HRAM) Mass Spectrometry Urine Steroid Profiling in the Diagnosis of Adrenal Disorders. Clin Chem. 2017 Dec; 63 (12):1824-1835 Epub 2017 Aug 16 View PubMed Dorshow RB, Hall-Moore C, Shaikh N, Talcott MR, Faubion WA, Rogers TE, Shieh JJ, Debreczeny MP, Johnson JR, Dyer RB, Singh RJ, Tarr PI. Measurement of gut permeability using fluorescent tracer agent technology. Sci Rep. 2017 Sep 7; 7 (1):10888 Epub 2017 Sept 07 View PubMed Ketha SS, Singh RJ, Ketha H. Role of Mass Spectrometry in Clinical Endocrinology. Endocrinol Metab Clin North Am. 2017 Sep; 46 (3):593-613 Epub 2017 June 08 View PubMed Iranmanesh A, Gullapalli D, Singh R, Veldhuis JD. Hypothalamo-pituitary-adrenal axis after a single epidural triamcinolone injection. Endocrine. 2017 Aug; 57 (2):308-313 Epub 2017 July 03 View PubMed Kosek MN, Lee GO, Guerrant RL, Haque R, Kang G, Ahmed T, Bessong P, Ali A, Mduma E, Penataro Yori P, Faubion WA, Lima AAM, Paredes Olortegui M, Mason C, Babji S, Singh R, Qureshi S, Kosek PS, Samie A, Pascal J, Shrestha S, McCormick BJJ, Seidman JC, Lang DR, Zaidi A, Caulfield LE, Gottlieb M, MAL-ED Network. Age and Sex Normalization of Intestinal Permeability Measures for the Improved Assessment of Enteropathy in Infancy and Early Childhood: Results From the MAL-ED Study. J Pediatr Gastroenterol Nutr. 2017 Jul; 65 (1):31-39 View PubMed Rahme M, Sharara SL, Baddoura R, Habib RH, Halaby G, Arabi A, Singh RJ, Kassem M, Mahfoud Z, Hoteit M, Daher RT, Bassil D, El Ferkh K, El-Hajj Fuleihan G. Impact of Calcium and Two Doses of Vitamin D on Bone Metabolism in the Elderly: A Randomized Controlled Trial. J Bone Miner Res. 2017 Jul; 32 (7):1486-1495 Epub 2017 May 18 View PubMed Peters SA, Edogawa S, Sundt WJ, Dyer RB, Dalenberg DA, Mazzone A, Singh RJ, Moses N, Smyrk TC, Weber C, Linden DR, MacNaughton WK, Turner JR, Camilleri M, Katzka DA, Farrugia G, Grover M. Constipation-Predominant Irritable Bowel Syndrome Females Have Normal Colonic Barrier and Secretory Function. Am J Gastroenterol. 2017 Jun; 112 (6):913-923 Epub 2017 Mar 21 View PubMed Chang AY, Lalia AZ, Jenkins GD, Dutta T, Carter RE, Singh RJ, Nair KS. Combining a nontargeted and targeted metabolomics approach to identify metabolic pathways significantly altered in polycystic ovary syndrome. Metabolism. 2017 Jun; 71:52-63 Epub 2017 Mar 08 View PubMed Eckard AR, Thierry-Palmer M, Silvestrov N, Rosebush JC, O'Riordan MA, Daniels JE, Uribe-Leitz M, Labbato D, Ruff JH, Singh RJ, Tangpricha V, McComsey GA. Effects of cholecalciferol supplementation on serum and urinary vitamin D metabolites and binding protein in HIV-infected youth. J Steroid Biochem Mol Biol. 2017 Apr; 168:38-48 Epub 2017 Feb 01 View PubMed Sturgeon CM, Sprague S, Almond A, Cavalier E, Fraser WD, Algeciras-Schimnich A, Singh R, Souberbielle JC, Vesper HW, IFCC Working Group for PTH. Perspective and priorities for improvement of parathyroid hormone (PTH) measurement - A view from the IFCC Working Group for PTH. Clin Chim Acta. 2017 Apr; 467:42-47. View PubMed Seger CD, He X, Braverman LE, Yeh MW, Bernet VJ, Singh RJ, Rhee CM, Leung AM. Negligible Thyroid Hormone Content Present in Nonprescription U.S. Weight Loss Products. Thyroid 2017 Feb; 27 (2):300-301 Epub 2016 Dec 22 View PubMed Stout MB, Steyn FJ, Jurczak MJ, Camporez JG, Zhu Y, Hawse JR, Jurk D, Palmer AK, Xu M, Pirtskhalava T, Evans GL, de Souza Santos R, Frank AP, White TA, Monroe DG, Singh RJ, Casaclang-Verzosa G, Miller JD, Clegg DJ, LeBrasseur NK, von Zglinicki T, Shulman GI, Tchkonia T, Kirkland JL. 17alpha-Estradiol Alleviates Age-related Metabolic and Inflammatory Dysfunction in Male Mice Without Inducing Feminization. J Gerontol A Biol Sci Med Sci. 2017 Jan; 72 (1):3-15 Epub 2016 Jan 24 View PubMed Mauras N, Ross JL, Gagliardi P, Yu YM, Hossain J, Permuy J, Damaso L, Merinbaum D, Singh RJ, Gaete X, Mericq V. Randomized Trial of Aromatase Inhibitors, Growth Hormone, or Combination in Pubertal Boys with Idiopathic, Short Stature. J Clin Endocrinol Metab. 2016 Dec; 101 (12):4984-4993 Epub 2016 Oct 06 View PubMed Veldhuis JD, Dyer RB, Trushin SA, Bondar OP, Singh RJ, Klee GG. Interleukins 6 and 8 and abdominal fat depots are distinct correlates of lipid moieties in healthy pre- and postmenopausal women. Endocrine. 2016 Dec; 54 (3):671-680 Epub 2016 July 22 View PubMed Grebe SKG, Singh RJ. Clinical peptide and protein quantification by mass spectrometry (ms) Trac-Trends In Analytical Chemistry. 2016 Nov; 84:131-43. Tebben PJ, Singh RJ, Kumar R. Vitamin D-Mediated Hypercalcemia: Mechanisms, Diagnosis, and Treatment. Endocr Rev. 2016 Oct; 37 (5):521-547 Epub 2016 Sept 02 View PubMed Kasiske BL, Kumar R, Kimmel PL, Pesavento TE, Kalil RS, Kraus ES, Rabb H, Posselt AM, Anderson-Haag TL, Steffes MW, Israni AK, Snyder JJ, Singh RJ, Weir MR. Abnormalities in biomarkers of mineral and bone metabolism in kidney donors. Kidney Int. 2016 Oct; 90 (4):861-8 Epub 2016 June 28 View PubMed O'Keeffe DT, Tebben PJ, Kumar R, Singh RJ, Wu Y, Wermers RA. Clinical and biochemical phenotypes of adults with monoallelic and biallelic CYP24A1 mutations: evidence of gene dose effect. Osteoporos Int. 2016 Oct; 27 (10):3121-5 Epub 2016 Apr 29 View PubMed El-Hajj Fuleihan G, Baddoura R, Habib RH, Halaby G, Arabi A, Rahme M, Singh RJ, Kassem M, Mahfoud Z, Hoteit M, Daher RT, Kassir MF. Effect of vitamin D replacement on indexes of insulin resistance in overweight elderly individuals: a randomized controlled trial. Am J Clin Nutr. 2016 Aug; 104 (2):315-23 Epub 2016 July 13 View PubMed Grover M, Camilleri M, Hines J, Burton D, Ryks M, Wadhwa A, Sundt W, Dyer R, Singh RJ. (13) C mannitol as a novel biomarker for measurement of intestinal permeability. Neurogastroenterol Motil. 2016 Jul; 28(7):1114-9. Epub 2016 Feb 23. View PubMed Kaur P, Singh RJ. Commentary. Clin Chem 2016 Jul; 62 (7):928 View PubMed Dutta T, Kudva YC, Persson XM, Schenck LA, Ford GC, Singh RJ, Carter R, Nair KS. Impact of Long-Term Poor and Good Glycemic Control on Metabolomics Alterations in Type 1 Diabetic People. J Clin Endocrinol Metab. 2016 Mar; 101 (3):1023-33 Epub 2016 Jan 21 View PubMed Gomez-Ospina N, Potter CJ, Xiao R, Manickam K, Kim MS, Kim KH, Shneider BL, Picarsic JL, Jacobson TA, Zhang J, He W, Liu P, Knisely AS, Finegold MJ, Muzny DM, Boerwinkle E, Lupski JR, Plon SE, Gibbs RA, Eng CM, Yang Y, Washington GC, Porteus MH, Berquist WE, Kambham N, Singh RJ, Xia F, Enns GM, Moore DD. Mutations in the nuclear bile acid receptor FXR cause progressive familial intrahepatic cholestasis. Nat Commun. 2016 Feb 18; 7:10713 View PubMed Ketha H, Singh RJ. Quantitation of Parathyroid Hormone in Serum or Plasma by Liquid Chromatography-Tandem Mass Spectrometry. Methods Mol Biol. 2016; 1378:211-7. View PubMed Ketha H, Singh RJ. Quantitation of Insulin-Like Growth Factor 1 in Serum by Liquid Chromatography High Resolution Accurate-Mass Mass Spectrometry. Methods Mol Biol. 2016; 1378:131-7. View PubMed Ketha H, Singh RJ. Quantitation of Albumin in Urine by Liquid Chromatography Tandem Mass Spectrometry. Methods Mol Biol. 2016; 1378:31-6. View PubMed Annesley T, Diamandis E, Bachmann L, Hanash S, Hart B, Javahery R, Singh R, Smith R. A Spectrum of Views on Clinical Mass Spectrometry. Clin Chem 2016 Jan; 62 (1):30-6 Epub 2015 Nov 09 View PubMed Hoofnagle AN, Whiteaker JR, Carr SA, Kuhn E, Liu T, Massoni SA, Thomas SN, Townsend RR, Zimmerman LJ, Boja E, Chen J, Crimmins DL, Davies SR, Gao Y, Hiltke TR, Ketchum KA, Kinsinger CR, Mesri M, Meyer MR, Qian WJ, Schoenherr RM, Scott MG, Shi T, Whiteley GR, Wrobel JA, Wu C, Ackermann BL, Aebersold R, Barnidge DR, Bunk DM, Clarke N, Fishman JB, Grant RP, Kusebauch U, Kushnir MM, Lowenthal MS, Moritz RL, Neubert H, Patterson SD, Rockwood AL, Rogers J, Singh RJ, Van Eyk JE, Wong SH, Zhang S, Chan DW, Chen X, Ellis MJ, Liebler DC, Rodland KD, Rodriguez H, Smith RD, Zhang Z, Zhang H, Paulovich AG. Recommendations for the Generation, Quantification, Storage, and Handling of Peptides Used for Mass Spectrometry-Based Assays. Clin Chem. 2016 Jan; 62 (1):48-69 View PubMed Ketha H, Kumar R, Singh RJ. LC-MS/MS for Identifying Patients with CYP24A1 Mutations. Clin Chem. 2016 Jan; 62 (1):236-42 Epub 2015 Nov 19 View PubMed Faubion WA, Camilleri M, Murray JA, Kelly P, Amadi B, Kosek MN, Enders F, Larson J, Grover M, Boe G, Dyer R, Singh R. Improving the detection of environmental enteric dysfunction: a lactulose, rhamnose assay of intestinal permeability in children aged under 5 years exposed to poor sanitation and hygiene. BMJ Glob Health. 2016; 1 (1):e000066 Epub 2016 July 04 View PubMed Bancos I, Erickson D, Bryant S, Hines J, Nippoldt TB, Natt N, Singh R. PERFORMANCE OF FREE VERSUS TOTAL CORTISOL FOLLOWING COSYNTROPIN STIMULATION TESTING IN AN OUTPATIENT SETTING. Endocr Pract. 2015 Dec; 21(12):1353-63. Epub 2015 Sep 04. View PubMed Demmer RT, Jacobs DR Jr, Singh R, Zuk A, Rosenbaum M, Papapanou PN, Desvarieux M. Periodontal Bacteria and Prediabetes Prevalence in ORIGINS: The Oral Infections, Glucose Intolerance, and Insulin Resistance Study. J Dent Res. 2015 Sep; 94 (9 Suppl):201S-11S Epub 2015 June 16 View PubMed Hawkes CP, Schnellbacher S, Singh RJ, Levine MA. 25-Hydroxyvitamin D Can Interfere With a Common Assay for 1,25-Dihydroxyvitamin D in Vitamin D Intoxication. J Clin Endocrinol Metab. 2015 Aug; 100 (8):2883-9 Epub 2015 June 29 View PubMed Thacher TD, Fischer PR, Singh RJ, Roizen J, Levine MA. CYP2R1 Mutations Impair Generation of 25-hydroxyvitamin D and Cause an Atypical Form of Vitamin D Deficiency. J Clin Endocrinol Metab. 2015 Jul; 100 (7):E1005-13 Epub 2015 May 05 View PubMed Ketha H, Girtman A, Singh RJ. Estradiol assays--The path ahead. Steroids. 2015 Jul; 99: (Pt A)39-44. View PubMed Fuleihan Gel-H, Bouillon R, Clarke B, Chakhtoura M, Cooper C, McClung M, Singh RJ. Serum 25-Hydroxyvitamin D Levels: Variability, Knowledge Gaps, and the Concept of a Desirable Range. J Bone Miner Res. 2015 Jul; 30 (7):1119-33 Epub 2015 May 07 View PubMed Ketha H, Singh RJ. Clinical assays for quantitation of insulin-like-growth-factor-1 (IGF1). Methods. 2015 Jun 15; 81:93-8 Epub 2015 Apr 30 View PubMed Binkley N, Lappe J, Singh RJ, Khosla S, Krueger D, Drezner MK, Blank RD. Can vitamin D metabolite measurements facilitate a "treat-to-target" paradigm to guide vitamin D supplementation? Osteoporos Int. 2015 May; 26(5):1655-60. View PubMed Dudenkov DV, Yawn BP, Oberhelman SS, Fischer PR, Singh RJ, Cha SS, Maxson JA, Quigg SM, Thacher TD. Changing Incidence of Serum 25-Hydroxyvitamin D Values Above 50 ng/mL: A 10-Year Population-Based Study. Mayo Clin Proc. 2015 May; 90 (5):577-86 View PubMed Ketha H, Wadams H, Lteif A, Singh RJ. Iatrogenic vitamin D toxicity in an infant--a case report and review of literature. J Steroid Biochem Mol Biol. 2015 Apr; 148:14-8. Epub 2015 Jan 27. View PubMed Ketha H, Singh RJ, Grebe SK, Bergstralh EJ, Rule AD, Lieske JC, Kumar R. Altered Calcium and Vitamin D Homeostasis in First-Time Calcium Kidney Stone-Formers. PLoS One. 2015; 10 (9):e0137350 Epub 2015 Sept 02 View PubMed Bergen HR 3rd, Farr JN, Vanderboom PM, Atkinson EJ, White TA, Singh RJ, Khosla S, LeBrasseur NK. Myostatin as a mediator of sarcopenia versus homeostatic regulator of muscle mass: insights using a new mass spectrometry-based assay. Skelet Muscle. 2015; 5:21. Epub 2015 Jul 15. View PubMed Liu DM, Torchen LC, Sung Y, Paparodis R, Legro RS, Grebe SK, Singh RJ, Taylor RL, Dunaif A. Evidence for gonadotrophin secretory and steroidogenic abnormalities in brothers of women with polycystic ovary syndrome. Hum Reprod. 2014 Dec; 29 (12):2764-72 Epub 2014 Oct 21 View PubMed Rahn DD, Good MM, Roshanravan SM, Shi H, Schaffer JI, Singh RJ, Word RA. Effects of preoperative local estrogen in postmenopausal women with prolapse: a randomized trial. J Clin Endocrinol Metab. 2014 Oct; 99 (10):3728-36 Epub 2014 June 20 View PubMed Klee EW, Bondar OP, Goodmanson MK, Trushin SA, Bergstralh EJ, Singh RJ, Anderson NL, Klee GG. Serum concentrations of prostate-specific antigen measured using immune extraction, trypsin digestion, and tandem mass spectrometry quantification of LSEPAELTDAVK peptide. Arch Pathol Lab Med. 2014 Oct; 138 (10):1381-6 View PubMed Lee GO, Kosek P, Lima AA, Singh R, Yori PP, Olortegui MP, Lamsam JL, Oliveira DB, Guerrant RL, Kosek M. Lactulose: mannitol diagnostic test by HPLC and LC-MSMS platforms: considerations for field studies of intestinal barrier function and environmental enteropathy. J Pediatr Gastroenterol Nutr. 2014 Oct; 59 (4):544-50 View PubMed Dube S, Norby B, Pattan V, Lingineni RK, Singh RJ, Carter RE, Basu A, Basu R. Hepatic 11beta-hydroxysteroid dehydrogenase type 1 activity in obesity and type 2 diabetes using a novel triple tracer cortisol technique. Diabetologia. 2014 Jul; 57 (7):1446-55 Epub 2014 Apr 26 View PubMed Ketha H, Kaur S, Grebe SK, Singh RJ. Clinical applications of LC-MS sex steroid assays: evolution of methodologies in the 21st century. Curr Opin Endocrinol Diabetes Obes. 2014 Jun; 21(3):217-26. View PubMed Veldhuis JD, Dyer RB, Trushin SA, Bondar OP, Singh RJ, Klee GG. Immunologic and mass-spectrometric estimates of SHBG concentrations in healthy women. Metabolism. 2014 Jun; 63 (6):783-92 Epub 2014 Mar 21 View PubMed Meekins ME, Oberhelman SS, Lee BR, Gardner BM, Cha SS, Singh RJ, Pettifor JM, Fischer PR, Thacher TD. Pharmacokinetics of daily versus monthly vitamin D3 supplementation in non-lactating women. Eur J Clin Nutr. 2014 May; 68 (5):632-4 Epub 2014 Jan 15 View PubMed Klee EW, Bondar OP, Goodmanson MK, Trushin SA, Singh RJ, Anderson NL, Klee GG. Mass spectrometry measurements of prostate-specific antigen (PSA) peptides derived from immune-extracted PSA provide a potential strategy for harmonizing immunoassay differences. Am J Clin Pathol. 2014 Apr; 141(4):527-33. View PubMed Nader NS, Castaneda RA, Wallace J, Singh R, Weaver A, Kumar S. Effect of vitamin d-3 supplementation on serum 25(oh)d, lipids and markers of insulin resistance in obese adolescents: a prospective, randomized, placebo-controlled pilot trial. Hormone Research In Paediatrics. 2014; 82(2):107-12. View PubMed Veldhuis JD, Bondar OP, Dyer RB, Trushin SA, Klee EW, Singh RJ, Klee GG. Immunological and mass spectrometric assays of SHBG: consistent and inconsistent metabolic associations in healthy men. J Clin Endocrinol Metab. 2014 Jan; 99 (1):184-93 Epub 2013 Dec 20 View PubMed Oberhelman SS, Meekins ME, Fischer PR, Lee BR, Singh RJ, Cha SS, Gardner BM, Pettifor JM, Croghan IT, Thacher TD. Maternal vitamin D supplementation to improve the vitamin D status of breast-fed infants: a randomized controlled trial. Mayo Clin Proc. 2013 Dec; 88 (12):1378-87 View PubMed Tolan NV, Vidal-Folch N, Algeciras-Schimnich A, Singh RJ, Grebe SK. Individualized correction of neuron-specific enolase (NSE) measurement in hemolyzed serum samples. Clin Chim Acta. 2013 Sep 23; 424:216-21. Epub 2013 Jun 15. View PubMed Cipriani C, Romagnoli E, Pepe J, Russo S, Carlucci L, Piemonte S, Nieddu L, McMahon DJ, Singh R, Minisola S. Long-term bioavailability after a single oral or intramuscular administration of 600,000 IU of ergocalciferol or cholecalciferol: implications for treatment and prophylaxis. J Clin Endocrinol Metab. 2013 Jul; 98(7):2709-15. Epub 2013 Jun 13. View PubMed Torres-Santiago L, Mericq V, Taboada M, Unanue N, Klein KO, Singh R, Hossain J, Santen RJ, Ross JL, Mauras N. Metabolic effects of oral versus transdermal 17beta-estradiol (E(2)): a randomized clinical trial in girls with Turner syndrome. J Clin Endocrinol Metab. 2013 Jul; 98(7):2716-24. Epub 2013 May 15. View PubMed Ryan ZC, Ketha H, McNulty MS, McGee-Lawrence M, Craig TA, Grande JP, Westendorf JJ, Singh RJ, Kumar R. Sclerostin alters serum vitamin D metabolite and fibroblast growth factor 23 concentrations and the urinary excretion of calcium. Proc Natl Acad Sci U S A. 2013 Apr 9; 110 (15):6199-204 Epub 2013 Mar 25 View PubMed Sood R, Warndahl RA, Schroeder DR, Singh RJ, Rhodes DJ, Wahner-Roedler D, Bahn RS, Shuster LT. Bioidentical compounded hormones: a pharmacokinetic evaluation in a randomized clinical trial. Maturitas. 2013 Apr; 74(4):375-82. Epub 2013 Feb 04. View PubMed Basaria S, Davda MN, Travison TG, Ulloor J, Singh R, Bhasin S. Risk factors associated with cardiovascular events during testosterone administration in older men with mobility limitation. J Gerontol A Biol Sci Med Sci. 2013 Feb; 68(2):153-60. Epub 2012 May 04. View PubMed Thacher TD, Fischer PR, Tebben PJ, Singh RJ, Cha SS, Maxson JA, Yawn BP. Increasing incidence of nutritional rickets: a population-based study in Olmsted County, Minnesota. Mayo Clin Proc. 2013 Feb; 88 (2):176-83 View PubMed Kasahara AK, Singh RJ, Noymer A. Vitamin D (25OHD) Serum Seasonality in the United States. PLoS One. 2013; 8(6):e65785. Epub 2013 Jun 21. View PubMed Pruthi S, Stan DL, Jenkins SM, Huebner M, Borg BA, Thomley BS, Cutshall SM, Singh R, Kohli S, Boughey JC, Lemaine V, Solberg Nes L. A Randomized Controlled Pilot Study Assessing Feasibility and Impact of Yoga Practice on Quality of Life, Mood, and Perceived Stress in Women With Newly Diagnosed Breast Cancer. Glob Adv Health Med. 2012 Nov; 1 (5):30-5 Epub 2012 Nov 01 View PubMed Craig TA, Zhang Y, McNulty MS, Middha S, Ketha H, Singh RJ, Magis AT, Funk C, Price ND, Ekker SC, Kumar R. Research resource: whole transcriptome RNA sequencing detects multiple 1alpha,25-dihydroxyvitamin D(3)-sensitive metabolic pathways in developing zebrafish. Mol Endocrinol. 2012 Sep; 26 (9):1630-42 Epub 2012 June 25 View PubMed Hagan JB, Netzel BC, Matthews MR, Korpi-Steiner NL, Singh RJ. Urinary fluticasone propionate-17beta-carboxylic acid to assess asthma therapy adherence. Allergy Asthma Proc. 2012 Jul-Aug; 33: (4)e35-9. View PubMed Bancos I, Grant CS, Nadeem S, Stan MN, Reading CC, Sebo TJ, Algeciras-Schimnich A, Singh RJ, Dean DS. Risks and benefits of parathyroid fine-needle aspiration with parathyroid hormone washout. Endocr Pract. 2012 Jul-Aug; 18 (4):441-9 View PubMed Kovacs K, Wagley S, Quirk MT, Ceron OM, Silva PA, Singh RJ, Gukasyan HJ, Arroyo JG. Pharmacokinetic study of vitreous and serum concentrations of triamcinolone acetonide after posterior sub-tenon's injection. Am J Ophthalmol. 2012 May; 153(5):939-48. Epub 2012 Feb 04. View PubMed Erickson D, Singh RJ, Sathananthan A, Vella A, Bryant SC. Late-night salivary cortisol for diagnosis of Cushing's syndrome by liquid chromatography/tandem mass spectrometry assay. Clin Endocrinol (Oxf). 2012 Apr; 76(4):467-72. View PubMed Bhasin S, Travison TG, Storer TW, Lakshman K, Kaushik M, Mazer NA, Ngyuen AH, Davda MN, Jara H, Aakil A, Anderson S, Knapp PE, Hanka S, Mohammed N, Daou P, Miciek R, Ulloor J, Zhang A, Brooks B, Orwoll K, Hede-Brierley L, Eder R, Elmi A, Bhasin G, Collins L, Singh R, Basaria S. Effect of testosterone supplementation with and without a dual 5alpha-reductase inhibitor on fat-free mass in men with suppressed testosterone production: a randomized controlled trial. JAMA. 2012 Mar 7; 307(9):931-9. View PubMed Tebben PJ, Milliner DS, Horst RL, Harris PC, Singh RJ, Wu Y, Foreman JW, Chelminski PR, Kumar R. Hypercalcemia, hypercalciuria, and elevated calcitriol concentrations with autosomal dominant transmission due to CYP24A1 mutations: effects of ketoconazole therapy. J Clin Endocrinol Metab. 2012 Mar; 97(3):E423-7. Epub 2012 Feb 15. View PubMed Barna BP, Culver DA, Kanchwala A, Singh RJ, Huizar I, Abraham S, Malur A, Marshall I, Kavuru MS, Thomassen MJ. Alveolar macrophage cathelicidin deficiency in severe sarcoidosis. J Innate Immun. 2012; 4(5-6):569-78. Epub 2012 Jul 03. View PubMed Aguirre Castaneda R, Nader N, Weaver A, Singh R, Kumar S. Response to vitamin D3 supplementation in obese and non-obese Caucasian adolescents. Horm Res Paediatr. 2012; 78 (4):226-31 Epub 2012 Oct 31 View PubMed Taboada M, Santen R, Lima J, Hossain J, Singh R, Oerter Klein K, Mauras N. Pharmacokinetics and pharmacodynamics of oral and transdermal 17beta estradiol in girls with turner syndrome. Obstet Gynecol Surv. 2012; 67(4):230-1. Taboada M, Santen R, Lima J, Hossain J, Singh R, Klein KO, Mauras N. Pharmacokinetics and pharmacodynamics of oral and transdermal 17beta estradiol in girls with Turner syndrome. J Clin Endocrinol Metab. 2011 Nov; 96(11):3502-10. Epub 2011 Aug 31. View PubMed Rao AS, Camilleri M, Eckert DJ, Busciglio I, Burton DD, Ryks M, Wong BS, Lamsam J, Singh R, Zinsmeister AR. Urine sugars for in vivo gut permeability: validation and comparisons in irritable bowel syndrome-diarrhea and controls. Am J Physiol Gastrointest Liver Physiol. 2011 Nov; 301 (5):G919-28 Epub 2011 Aug 11 View PubMed Kleerekoper M, Schleicher RL, Eisman J, Bouillon R, Singh RJ, Holick MF. Clinical applications for vitamin D assays: what is known and what is wished for. Clin Chem. 2011 Sep; 57(9):1227-32. Epub 2011 Apr 18. View PubMed Bhasin S, Pencina M, Jasuja GK, Travison TG, Coviello A, Orwoll E, Wang PY, Nielson C, Wu F, Tajar A, Labrie F, Vesper H, Zhang A, Ulloor J, Singh R, D'Agostino R, Vasan RS. Reference ranges for testosterone in men generated using liquid chromatography tandem mass spectrometry in a community-based sample of healthy nonobese young men in the Framingham Heart Study and applied to three geographically distinct cohorts. J Clin Endocrinol Metab. 2011 Aug; 96(8):2430-9. Epub 2011 Jun 22. View PubMed Hagan JB, Taylor RL, Kita H, Singh RJ. Analysis of fluticasone propionate in induced sputum by mass spectrometry. Allergy Asthma Proc. 2011 Jul-Aug; 32: (4)18-21. View PubMed McNulty M, Singh RJ, Li X, Bergstralh EJ, Kumar R. Determination of serum and plasma sclerostin concentrations by enzyme-linked immunoassays. J Clin Endocrinol Metab. 2011 Jul; 96 (7):E1159-62 Epub 2011 May 04 View PubMed Netzel BC, Cradic KW, Bro ET, Girtman AB, Cyr RC, Singh RJ, Grebe SK. Increasing liquid chromatography-tandem mass spectrometry throughput by mass tagging: a sample-multiplexed high-throughput assay for 25-hydroxyvitamin D2 and D3. Clin Chem. 2011 Mar; 57 (3):431-40 Epub 2011 Jan 18 View PubMed Kunisaki KM, Niewoehner DE, Singh RJ, Connett JE. Vitamin D status and longitudinal lung function decline in the Lung Health Study. Eur Respir J. 2011 Feb; 37(2):238-43. Epub 2010 Jul 01. View PubMed Pruthi S, Haakenson C, Brost BC, Bryant K, Reid JM, Singh R, Netzel B, Boughey JC, Degnim AC. Pharmacokinetics of methylene blue dye for lymphatic mapping in breast cancer-implications for use in pregnancy. Am J Surg. 2011 Jan; 201(1):70-5. View PubMed Hackbarth JS, Hoyne JB, Grebe SK, Singh RJ. Accuracy of calculated free testosterone differs between equations and depends on gender and SHBG concentration. Steroids. 2011 Jan; 76 (1-2):48-55 View PubMed Sarafoglou K, Himes JH, Lacey JM, Netzel BC, Singh RJ, Matern D. Comparison of multiple steroid concentrations in serum and dried blood spots throughout the day of patients with congenital adrenal hyperplasia. Horm Res Paediatr. 2011; 75(1):19-25. Epub 2010 Aug 25 View PubMed Nader NS, Bahn RS, Johnson MD, Weaver AL, Singh R, Kumar S. Relationships between thyroid function and lipid status or insulin resistance in a pediatric population. Thyroid. 2010 Dec; 20 (12):1333-9 View PubMed Rao AS, Wong BS, Camilleri M, Odunsi-Shiyanbade ST, McKinzie S, Ryks M, Burton D, Carlson P, Lamsam J, Singh R, Zinsmeister AR. Chenodeoxycholate in females with irritable bowel syndrome-constipation: a pharmacodynamic and pharmacogenetic analysis. Gastroenterology. 2010 Nov; 139 (5):1549-58, 1558.e1 Epub 2010 Aug 04 View PubMed Zerikly RK, Amiri L, Faiman C, Gupta M, Singh RJ, Nutter B, Kennedy L, Hatipoglu B, Weil RJ, Hamrahian AH. Diagnostic characteristics of late-night salivary cortisol using liquid chromatography-tandem mass spectrometry. J Clin Endocrinol Metab. 2010 Oct; 95(10):4555-9. Epub 2010 Jul 14. View PubMed Drake MT, Maurer MJ, Link BK, Habermann TM, Ansell SM, Micallef IN, Kelly JL, Macon WR, Nowakowski GS, Inwards DJ, Johnston PB, Singh RJ, Allmer C, Slager SL, Weiner GJ, Witzig TE, Cerhan JR. Vitamin D insufficiency and prognosis in non-Hodgkin's lymphoma. J Clin Oncol. 2010 Sep 20; 28 (27):4191-8 Epub 2010 Aug 16 View PubMed Thacher TD, Fischer PR, Obadofin MO, Levine MA, Singh RJ, Pettifor JM. Comparison of metabolism of vitamins D-2 and D-3 in children with nutritional rickets. J Bone Miner Res. 2010 Sep; 25(9):1988-95. Lodish MB, Adams KT, Huynh TT, Prodanov T, Ling A, Chen C, Shusterman S, Jimenez C, Merino M, Hughes M, Cradic KW, Milosevic D, Singh RJ, Stratakis CA, Pacak K. Succinate dehydrogenase gene mutations are strongly associated with paraganglioma of the organ of Zuckerkandl. Endocr Relat Cancer. 2010 Sep; 17(3):581-8. Epub 2010 Jun 03. View PubMed Thacher TD, Fischer PR, Obadofin MO, Levine MA, Singh RJ, Pettifor JM. Comparison of metabolism of vitamins D2 and D3 in children with nutritional rickets. J Bone Miner Res. 2010 Sep; 25 (9):1988-95 View PubMed Lee S, Kwon S, Shin HJ, Lim HS, Singh RJ, Lee KR, Kim YJ. Simultaneous quantitative analysis of salivary cortisol and cortisone in Korean adults using LC-MS/MS. BMB Rep. 2010 Jul; 43(7):506-11. View PubMed Hagan JB, Erickson D, Singh RJ. Triamcinolone acetonide induced secondary adrenal insufficiency related to impaired CYP3A4 metabolism by coadministration of nefazodone. Pain Med. 2010 Jul; 11 (7):1132-5 Epub 2010 Apr 29 View PubMed Anderson H, Fogel N, Grebe SK, Singh RJ, Taylor RL, Dunaif A. Infants of women with polycystic ovary syndrome have lower cord blood androstenedione and estradiol levels. J Clin Endocrinol Metab. 2010 May; 95(5):2180-6. Epub 2010 Mar 12. View PubMed Johnson MD, Nader NS, Weaver AL, Singh R, Kumar S. Relationships between 25-hydroxyvitamin D levels and plasma glucose and lipid levels in pediatric outpatients. J Pediatr. 2010 Mar; 156 (3):444-9 Epub 2009 Nov 18 View PubMed Odunsi-Shiyanbade ST, Camilleri M, McKinzie S, Burton D, Carlson P, Busciglio IA, Lamsam J, Singh R, Zinsmeister AR. Effects of chenodeoxycholate and a bile acid sequestrant, colesevelam, on intestinal transit and bowel function. Clin Gastroenterol Hepatol. 2010 Feb; 8 (2):159-65 Epub 2009 Oct 30 View PubMed Lopez MF, Rezai T, Sarracino DA, Prakash A, Krastins B, Athanas M, Singh RJ, Barnidge DR, Oran P, Borges C, Nelson RW. Selected reaction monitoring-mass spectrometric immunoassay responsive to parathyroid hormone and related variants. Clin Chem. 2010 Feb; 56(2):281-90. Epub 2009 Dec 18. View PubMed Kumar V, Barnidge DR, Chen LS, Twentyman JM, Cradic KW, Grebe SK, Singh RJ. Quantification of serum 1-84 parathyroid hormone in patients with hyperparathyroidism by immunocapture in situ digestion liquid chromatography-tandem mass spectrometry. Clin Chem. 2010 Feb; 56(2):306-13. Epub 2009 Dec 10. View PubMed Korpi-Steiner NL, Netzel BC, Seegmiller JC, Hagan JB, Singh RJ. Liquid chromatography-tandem mass spectrometry analysis of urinary fluticasone propionate-17beta-carboxylic acid for monitoring compliance with inhaled-fluticasone propionate therapy. Steroids. 2010 Jan; 75(1):77-82. Epub 2009 Oct 31. View PubMed Camilleri M, Nadeau A, Lamsam J, Nord SL, Ryks M, Burton D, Sweetser S, Zinsmeister AR, Singh R. Understanding measurements of intestinal permeability in healthy humans with urine lactulose and mannitol excretion. Neurogastroenterol Motil. 2010 Jan; 22 (1):e15-26 Epub 2009 July 13 View PubMed Singh RJ. Quantitation of 25-OH-vitamin D (25OHD) using liquid tandem mass spectrometry (LC-MS-MS). Methods Mol Biol. 2010; 603:509-17. View PubMed Singh RJ. Quantitation of 17-OH-progesterone (OHPG) for diagnosis of congenital adrenal hyperplasia (CAH). Methods Mol Biol. 2010; 603:271-7. View PubMed Diabetes Research in Children Network (DirecNet) Study Group, Tsalikian E, Tamborlane W, Xing D, Becker DM, Mauras N, Fiallo-Scharer R, Buckingham B, Weinzimer S, Steffes M, Singh R, Beck R, Ruedy K, Kollman C. Blunted counterregulatory hormone responses to hypoglycemia in young children and adolescents with well-controlled type 1 diabetes. Diabetes Care. 2009 Nov; 32(11):1954-9. Epub 2009 Aug 12. View PubMed Camilleri M, Nadeau A, Tremaine WJ, Lamsam J, Burton D, Odunsi S, Sweetser S, Singh R. Measurement of serum 7alpha-hydroxy-4-cholesten-3-one (or 7alphaC4), a surrogate test for bile acid malabsorption in health, ileal disease and irritable bowel syndrome using liquid chromatography-tandem mass spectrometry. Neurogastroenterol Motil. 2009 Jul; 21 (7):734-e43 Epub 2009 Mar 13 View PubMed Vesper HW, Bhasin S, Wang C, Tai SS, Dodge LA, Singh RJ, Nelson J, Ohorodnik S, Clarke NJ, Salameh WA, Parker CR, Razdan R, Monsell EA, Myers GL. Interlaboratory comparison study of serum total testosterone [corrected] measurements performed by mass spectrometry methods. Steroids. 2009 Jun; 74(6):498-503. Epub 2009 Jan 30. View PubMed Silva PS, Singh RJ, Bakri SJ, Lising RS, Santiago DE, Uy HS. Vitreous concentration of triamcinolone acetonide after a single transseptal depot injection. Ocul Immunol Inflamm. 2009 May-Jun; 17(3):216-20. View PubMed Basu R, Basu A, Grudzien M, Jung P, Jacobson P, Johnson M, Singh R, Sarr M, Rizza RA. Liver is the site of splanchnic cortisol production in obese nondiabetic humans. Diabetes. 2009 Jan; 58 (1):39-45 Epub 2008 Oct 13 View PubMed Liu Y, Singh RJ, Usa K, Netzel BC, Liang M. Renal medullary 11 beta-hydroxysteroid dehydrogenase type 1 in Dahl salt-sensitive hypertension. Physiol Genomics. 2008 Dec 12; 36(1):52-8. Epub 2008 Sep 30. View PubMed Bhasin S, Zhang A, Coviello A, Jasuja R, Ulloor J, Singh R, Vesper H, Vasan RS. The impact of assay quality and reference ranges on clinical decision making in the diagnosis of androgen disorders. Steroids. 2008 Dec 12; 73(13):1311-7. Epub 2008 Jul 17. View PubMed Santen RJ, Lee JS, Wang S, Demers LM, Mauras N, Wang H, Singh R. Potential role of ultra-sensitive estradiol assays in estimating the risk of breast cancer and fractures. Steroids. 2008 Dec 12; 73(13):1318-21. Epub 2008 Jul 09. View PubMed Singh RJ. Validation of a high throughput method for serum/plasma testosterone using liquid chromatography tandem mass spectrometry (LC-MS/MS). Steroids. 2008 Dec 12; 73 (13):1339-44 Epub 2008 July 25 View PubMed Singh RJ. Improving Patient Care with Tandem Mass Spectrometry. Clin Lab News. 2008 Dec; 34(12):52-54 Epub 2008 Dec. Khosla S, Amin S, Singh RJ, Atkinson EJ, Melton LJ 3rd, Riggs BL. Comparison of sex steroid measurements in men by immunoassay versus mass spectroscopy and relationships with cortical and trabecular volumetric bone mineral density. Osteoporos Int. 2008 Oct; 19 (10):1465-71 Epub 2008 Mar 13 View PubMed Shaikh A, Seegmiller JC, Borland TM, Burns BE, Ladwig PM, Singh RJ, Kumar R, Larson TS, Lieske JC. Comparison between immunoturbidimetry, size-exclusion chromatography, and LC-MS to quantify urinary albumin. Clin Chem. 2008 Sep; 54(9):1504-10. Epub 2008 Jul 10. View PubMed Gross KL, Westberry JM, Hubler TR, Sadosky PW, Singh RJ, Taylor RL, Scammell JG. Androgen resistance in squirrel monkeys (Saimiri spp.). Comp Med. 2008 Aug; 58(4):381-8. View PubMed Guo T, Gu J, Soldin OP, Singh RJ, Soldin SJ. Rapid measurement of estrogens and their metabolites in human serum by liquid chromatography-tandem mass spectrometry without derivatization. Clin Biochem. 2008 Jun; 41(9):736-41. Epub 2008 Mar 07. View PubMed Mauras N, Gonzalez de Pijem L, Hsiang HY, Desrosiers P, Rapaport R, Schwartz ID, Klein KO, Singh RJ, Miyamoto A, Bishop K. Anastrozole increases predicted adult height of short adolescent males treated with growth hormone: a randomized, placebo-controlled, multicenter trial for one to three years. J Clin Endocrinol Metab. 2008 Mar; 93(3):823-31. Epub 2007 Dec 28. View PubMed Liu Y, Park F, Pietrusz JL, Jia G, Singh RJ, Netzel BC, Liang M. Suppression of 11beta-hydroxysteroid dehydrogenase type 1 with RNA interference substantially attenuates 3T3-L1 adipogenesis. Physiol Genomics. 2008 Feb 19; 32(3):343-51. Epub 2007 Dec 11. View PubMed Chang SC, Thibodeaux JR, Eastvold ML, Ehresman DJ, Bjork JA, Froehlich JW, Lau C, Singh RJ, Wallace KB, Butenhoff JL. Thyroid hormone status and pituitary function in adult rats given oral doses of perfluorooctanesulfonate (PFOS). Toxicology. 2008 Jan 20; 243(3):330-9. Epub 2007 Oct 26. View PubMed Singh R, Bruton J, Quantitative Analysis of Testosterone in Serum by LC-MS/MS. Quantitative Analysis of Testosterone in Serum by LC-MS/MS. Thermo Scientific. 2008. Algeciras-Schimnich A, Preissner CM, Young WF Jr, Singh RJ, Grebe SK. Plasma chromogranin A or urine fractionated metanephrines follow-up testing improves the diagnostic accuracy of plasma fractionated metanephrines for pheochromocytoma. J Clin Endocrinol Metab. 2008 Jan; 93 (1):91-5 Epub 2007 Oct 16 View PubMed Englert RC, Dauser D, Gilchrist A, Samociuk HA, Singh RJ, Kesner JS, Cuthbert CD, Zarfos K, Gregorio DI, Stevens RG. Marital status and variability in cortisol excretion in postmenopausal women. Biol Psychol. 2008 Jan; 77(1):32-8. Epub 2007 Sep 02. View PubMed Bakri SJ, Snyder MR, Reid JM, Pulido JS, Ezzat MK, Singh RJ. Pharmacokinetics of intravitreal ranibizumab (Lucentis). Ophthalmology. 2007 Dec; 114 (12):2179-82 View PubMed Snozek CL, Chambers EP, Reading CC, Sebo TJ, Sistrunk JW, Singh RJ, Grebe SK. Serum thyroglobulin, high-resolution ultrasound, and lymph node thyroglobulin in diagnosis of differentiated thyroid carcinoma nodal metastases. J Clin Endocrinol Metab. 2007 Nov; 92: (11)4278-81. View PubMed Usa K, Singh RJ, Netzel BC, Liu Y, Raff H, Liang M. Renal interstitial corticosterone and 11-dehydrocorticosterone in conscious rats. Am J Physiol Renal Physiol. 2007 Jul; 293(1):F186-92. Epub 2007 Mar 27. View PubMed Chang SC, Thibodeaux JR, Eastvold ML, Ehresman DJ, Bjork JA, Froehlich JW, Lau CS, Singh RJ, Wallace KB, Butenhoff JL. Negative bias from analog methods used in the analysis of free thyroxine in rat serum containing perfluorooctanesulfonate (PFOS). Toxicology. 2007 May 5; 234(1-2):21-33. View PubMed Bakri SJ, Snyder MR, Reid JM, Pulido JS, Singh RJ. Pharmacokinetics of intravitreal bevacizumab (Avastin). Ophthalmology. 2007 May; 114 (5):855-9 View PubMed Perry CG, Sawka AM, Singh R, Thabane L, Bajnarek J, Young WF Jr. The diagnostic efficacy of urinary fractionated metanephrines measured by tandem mass spectrometry in detection of pheochromocytoma. Clin Endocrinol (Oxf). 2007 May; 66: (5)703-8. View PubMed Kidambi S, Kotchen JM, Grim CE, Raff H, Mao J, Singh RJ, Kotchen TA. Association of adrenal steroids with hypertension and the metabolic syndrome in blacks. Hypertension. 2007 Mar; 49(3):704-11. View PubMed Chase PH, Fiallo-Scharer R, Fisher JH, Tallant B, Tsalikian E, Tansey MJ, Larson LF, Coffey J, Wysocki T, Mauras N, Fox LA, Bird K, Lofton KL, Buckingham BA, Wilson DM, Block JM, Clinton P, Weinzimer SA, Tamborlane WV, Doyle EA, Sikes K, Beck RW, Ruedy KJ, Kollman C, Xing D, Kalajian A, Stockdale CR, Steffes MW, Bucksa JM, Nowicki ML, Van Hale CA, Makky V, Singh R, Grave GD, Linder B, Winer KK, Becker DM, Cox C, Ryan CM, White NH, White PC. Impaired overnight counterregulatory hormone responses to spontaneous hypoglycemia in children with type 1 diabetes. Pediatr Diabetes. 2007; 8(4):199-205. Singh RJ. Diagnosing hypercortisolism. MLO Med Lab Obs. 2006 Dec; 38(12):20. View PubMed Babic N, Larson TS, Grebe SK, Turner ST, Kumar R, Singh RJ. Application of liquid chromatography-mass spectrometry technology for early detection of microalbuminuria in patients with kidney disease. Clin Chem. 2006 Nov; 52 (11):2155-7 View PubMed Basu R, Edgerton DS, Singh RJ, Cherrington A, Rizza RA. Splanchnic cortisol production in dogs occurs primarily in the liver: evidence for substantial hepatic specific 11beta hydroxysteroid dehydrogenase type 1 activity. Diabetes. 2006 Nov; 55(11):3013-9. View PubMed Guo T, Taylor RL, Singh RJ, Soldin SJ. Simultaneous determination of 12 steroids by isotope dilution liquid chromatography-photospray ionization tandem mass spectrometry. Clin Chim Acta. 2006 Oct; 372(1-2):76-82. Epub 2006 Apr 03. View PubMed Singh RJ, Taylor RL, Reddy GS, Grebe SK. C-3 epimers can account for a significant proportion of total circulating 25-hydroxyvitamin D in infants, complicating accurate measurement and interpretation of vitamin D status. J Clin Endocrinol Metab. 2006 Aug; 91 (8):3055-61 Epub 2006 May 23 View PubMed Bakri SJ, Snyder MR, Pulido JS, McCannel CA, Weiss WT, Singh RJ. Six-month stability of bevacizumab (Avastin) binding to vascular endothelial growth factor after withdrawal into a syringe and refrigeration or freezing. Retina. 2006 May-Jun; 26 (5):519-22 View PubMed Eastvold ML, Wallinder HW, Preissner CM, Singh RJ, Lowbeer C, Grebe SK. A two-center international evaluation of the Immulite 2000 automated serum gastrin assay. Clin Biochem. 2006 Apr; 39 (4):387-90 Epub 2006 Feb 07 View PubMed Scammell JG, Westberry JM, Sadosky PW, Hubler TR, Williams LE, Gibson SV, Singh RJ, Taylor RL, Shackleton CH. Cortisol metabolism in the Bolivian squirrel monkey (Saimiri boliviensis boliviensis). Comp Med. 2006 Apr; 56(2):128-35. View PubMed Basu R, Singh R, Basu A, Johnson CM, Johnson CM, Rizza RA. Effect of nutrient ingestion on total-body and splanchnic cortisol production in humans. Diabetes. 2006 Mar; 55 (3):667-74 View PubMed Costello P, Bakri SJ, Beer PM, Singh RJ, Falk NS, Peters GB, Melendez JA. Vitreous penetration of topical moxifloxacin and gatifloxacin in humans. Retina. 2006 Feb; 26(2):191-5. View PubMed Toran-Allerand CD, Tinnikov AA, Singh RJ, Nethrapalli IS. 17 alpha-estradiol: A brain-active estrogen? Endocrinology. 2005 Sep; 146(9):3843-50. View PubMed Basu R, Singh RJ, Basu A, Chittilapilly EG, Johnson MC, Toffolo G, Cobelli C, Rizza RA. Obesity and type 2 diabetes do not alter splanchnic cortisol production in humans. J Clin Endocrinol Metab. 2005 Jul; 90(7):3919-26. Epub 2005 Apr 05. View PubMed Rajamannan NM, Subramaniam M, Stock SR, Stone NJ, Springett M, Ignatiev KI, McConnell JP, Singh RJ, Bonow RO, Spelsberg TC. Atorvastatin inhibits calcification and enhances nitric oxide synthase production in the hypercholesterolaemic aortic valve. Heart (British Cardiac Society). 2005 Jun; 91: (6)806-10. View PubMed Tebben PJ, Kalli KR, Cliby WA, Hartmann LC, Grande JP, Singh RJ, Kumar R. Elevated fibroblast growth factor 23 in women with malignant ovarian tumors. Mayo Clin Proc. 2005 Jun; 80 (6):745-51 View PubMed Short KR, Bigelow ML, Kahl J, Singh R, Coenen-Schimke J, Raghavakaimal S, Nair KS. Decline in skeletal muscle mitochondrial function with aging in humans. Proc Natl Acad Sci U S A. 2005 Apr 12; 102 (15):5618-23 Epub 2005 Mar 30 View PubMed Preissner CM, Dodge LA, O'Kane DJ, Singh RJ, Grebe SK. Prevalence of heterophilic antibody interference in eight automated tumor marker immunoassays. Clin Chem. 2005 Jan; 51 (1):208-10 View PubMed Gomez EA, Ehresmann DD, Ledebuhr LK, Eastvold ML, Singh RJ, Klee GG, Grebe SK. Development and validation of an automated chemiluminometric immunoassay for human intrinsic factor antibodies in serum. Clin Chem. 2005 Jan; 51(1):232-5. View PubMed Mason JO, Somaiya MD, Singh RJ. Intravitreal concentration and clearance of triamcinolone acetonide in nonvitrectomized human eyes. Retina: the Journal of Retinal & Vitreous Diseases. 2004 Dec; 24(6):900-4. View PubMed Taylor RL, Grebe SK, Singh RJ. Quantitative, highly sensitive liquid chromatography-tandem mass spectrometry method for detection of synthetic corticosteroids. Clin Chem. 2004 Dec; 50 (12):2345-52 Epub 2004 Oct 14 View PubMed Tebben PJ, Singh RJ, Clarke BL, Kumar R. Fibroblast growth factor 23, parathyroid hormone, and 1alpha,25-dihydroxyvitamin D in surgically treated primary hyperparathyroidism. Mayo Clin Proc. 2004 Dec; 79 (12):1508-13 View PubMed Basu R, Singh RJ, Basu A, Chittilapilly EG, Johnson CM, Toffolo G, Johnson CM, Cobelli C, Rizza RA. Splanchnic cortisol production occurs in humans: evidence for conversion of cortisone to cortisol via the 11-beta hydroxysteroid dehydrogenase (11beta-hsd) type 1 pathway. Diabetes. 2004 Aug; 53 (8):2051-9 View PubMed Svatikova A, Wolk R, Wang HH, Otto ME, Bybee KA, Singh RJ, Somers VK. Circulating free nitrotyrosine in obstructive sleep apnea. Am J Physiol Regul Integr Comp Physiol. 2004 Aug; 287 (2):R284-7 Epub 2004 May 13 View PubMed Preissner CM, Reilly WM, Cyr RC, O'Kane DJ, Singh RJ, Grebe SK. Plastic versus glass tubes: effects on analytical performance of selected serum and plasma hormone assays. Clin Chem. 2004 Jul; 50 (7):1245-7 View PubMed Kumar S, Singh RJ, Reed AM, Lteif AN. Cushing's syndrome after intra-articular and intradermal administration of triamcinolone acetonide in three pediatric patients. Pediatrics. 2004 Jun; 113 (6):1820-4 View PubMed Cradic KW, Wells JE, Allen L, Kruckeberg KE, Singh RJ, Grebe SK. Substitution of 3'-phosphate cap with a carbon-based blocker reduces the possibility of fluorescence resonance energy transfer probe failure in real-time PCR assays. Clin Chem. 2004 Jun; 50 (6):1080-2 View PubMed Singh RJ. Advances in metanephrine testing for the diagnosis of pheochromocytoma. Clin Lab Med. 2004 Mar; 24(1):85-103. View PubMed Lagerstedt SA, O'Kane DJ, Singh RJ. Measurement of plasma free metanephrine and normetanephrine by liquid chromatography-tandem mass spectrometry for diagnosis of pheochromocytoma. Clin Chem. 2004 Mar; 50 (3):603-11 Epub 2004 Jan 15 View PubMed Nelson RE, Grebe SK, OKane DJ, OKane DJ, Singh RJ. Liquid chromatography-tandem mass spectrometry assay for simultaneous measurement of estradiol and estrone in human plasma. Clin Chem. 2004 Feb; 50 (2):373-84 Epub 2003 Dec 04 View PubMed Singh RJ, Kumar R. Fibroblast growth factor 23 concentrations in humoral hypercalcemia of malignancy and hyperparathyroidism. Mayo Clin Proc. 2003 Jul; 78 (7):826-9 View PubMed Preissner CM, O'Kane DJ, Singh RJ, Morris JC, Grebe SK. Phantoms in the assay tube: heterophile antibody interferences in serum thyroglobulin assays. J Clin Endocrinol Metab. 2003 Jul; 88 (7):3069-74 View PubMed Sawka AM, Jaeschke R, Singh RJ, Young WF Jr. A comparison of biochemical tests for pheochromocytoma: measurement of fractionated plasma metanephrines compared with the combination of 24-hour urinary metanephrines and catecholamines. J Clin Endocrinol Metab. 2003 Feb; 88 (2):553-8 View PubMed Taylor RL, Machacek D, Singh RJ. Validation of a high-throughput liquid chromatography-tandem mass spectrometry method for urinary cortisol and cortisone. Clin Chem. 2002 Sep; 48 (9):1511-9 View PubMed Rajamannan NM, Subramaniam M, Springett M, Sebo TC, Niekrasz M, McConnell JP, Singh RJ, Stone NJ, Bonow RO, Spelsberg TC. Atorvastatin inhibits hypercholesterolemia-induced cellular proliferation and bone matrix production in the rabbit aortic valve. Circulation. 2002 Jun 4; 105(22):2660-5. View PubMed Sato J, O'Brien T, Katusic ZS, Fu A, Nygren J, Singh R, Nair KS. Dietary antioxidants preserve endothelium dependent vasorelaxation in overfed rats. Atherosclerosis. 2002 Apr; 161 (2):327-33 View PubMed Taylor RL, Singh RJ. Validation of liquid chromatography-tandem mass spectrometry method for analysis of urinary conjugated metanephrine and normetanephrine for screening of pheochromocytoma. Clin Chem. 2002 Mar; 48 (3):533-9 View PubMed Sawka AM, Singh RJ, Young WF. False positive biochemical testing for pheochromocytoma caused by surreptitious catecholamine addition to urine. Endocrinologist. 2001 Sep-Oct; 11(5):421-423. Sawka AM, Singh RJ, Hiddinga HJ, McConnell JP, Eberhardt NL, Caplice NM, O'Brien T. Remnant lipoproteins induce endothelial plasminogen activator inhibitor-1. Biochem Biophys Res Commun. 2001 Jul 6; 285(1):15-9. View PubMed Baker JE, Contney SJ, Singh R, Kalyanaraman B, Gross GJ, Bosnjak ZJ. Nitric oxide activates the sarcolemmal K(ATP) channel in normoxic and chronically hypoxic hearts by a cyclic GMP-dependent mechanism. J Mol Cell Cardiol. 2001 Feb; 33(2):331-41. View PubMed Sato J, Singh RJ, I'Brien T, Katusic ZS, Fu A, Nygren JA, Nair KS. Dietary antioxidants preserve endothelium dependent vasorelaxation in obese rats. Clin Chem. 2000 Jun; 46: (6)398. Goss SP, Singh RJ, Hogg N, Kalyanaraman B. Reactions of *NO, *NO2 and peroxynitrite in membranes: physiological implications. Free Radic Res Review. 1999 Dec; 31(6):597-606. Ferguson E, Hogg N, Antholine WE, Joseph J, Singh RJ, Parthasarathy S, Kalyanaraman B. Characterization of the adduct formed from the reaction between homocysteine thiolactone and low-density lipoprotein: antioxidant implications. Free Radic Biol Med. 1999 Apr; 26(7-8):968-77. View PubMed Singh RJ, Hogg N, Joseph J, Konorev E, Kalyanaraman B. The peroxynitrite generator, SIN-1, becomes a nitric oxide donor in the presence of electron acceptors. Arch Biochem Biophys. 1999 Jan 15; 361(2):331-9. View PubMed Singh RJ, Hogg N, Goss SP, Antholine WE, Kalyanaraman B. Mechanism of superoxide dismutase/H2O2-mediated nitric oxide release from S-nitrosoglutathione--Role of glutamate. Arch Biochem Biophys. 1999; 372:8-15. View PubMed Janssen YM, Soultanakis R, Steece K, Heerdt E, Singh RJ, Joseph J, Kalyanaraman B. Depletion of nitric oxide causes cell cycle alterations, apoptosis, and oxidative stress in pulmonary cells. Am J Physiol. 1998 Dec; 275(6 Pt 1):L1100-9. View PubMed Singh RJ, Goss SP, Joseph J, Kalyanaraman B. Nitration of gamma-tocopherol and oxidation of alpha-tocopherol by copper-zinc superoxide dismutase/H2O2/NO2-: role of nitrogen dioxide free radical. Proc Natl Acad Sci U S A. 1998 Oct 27; 95 (22):12912-7 View PubMed Singh RJ, Karoui H, Gunther MR, Beckman JS, Mason RP, Kalyanaraman B. Reexamination of the mechanism of hydroxyl radical adducts formed from the reaction between familial amyotrophic lateral sclerosis-associated Cu,Zn superoxide dismutase mutants and H2O2. Proc Natl Acad Sci U S A. 1998 Jun 9; 95(12):6675-80. View PubMed Ferguson E, Singh RJ, Hogg N, Kalyanaraman B. The mechanism of apolipoprotein B-100 thiol depletion during oxidative modification of low-density lipoprotein. Arch Biochem Biophys. 1997 May 15; 341(2):287-94. View PubMed Hogg N, Singh RJ, Konorev E, Joseph J, Kalyanaraman B. S-Nitrosoglutathione as a substrate for gamma-glutamyl transpeptidase. Biochem J 323 (. 1997 Apr 15; Pt 2): 477-81. Kalyanaraman B, Karoui H, Singh RJ, Felix CC. Detection of thiyl radical adducts formed during hydroxyl radical- and peroxynitrite-mediated oxidation of thiols--a high resolution ESR spin-trapping study at Q-band (35 GHz). Anal Biochem 1. 1996 Oct; 241: (1)75-81. Singh RJ, Hogg N, Joseph J, Kalyanaraman B. Mechanism of nitric oxide release from S-nitrosothiols. J of Biol Chem 2. 1996 Aug; 271: (31)18596-603. Hogg N, Singh RJ, Goss SP, Kalyanaraman B. The reaction between nitric oxide and alpha-tocopherol: a reappraisal. Biochem Biophys Res Commun. 1996 Jul 25; 224(3):696-702. View PubMed Hogg N, Singh RJ, Kalyanaraman B. The role of glutathione in the transport and catabolism of nitric oxide. FEBS Lett. 1996 Mar 18; 382(3):223-8. View PubMed Singh RJ, Hogg N, Kalyanaraman B. Interaction of nitric oxide with photoexcited rose bengal: evidence for one-electron reduction of nitric oxide to nitroxyl anion. Arch Biochem Biophys. 1995 Dec 20; 324(2):367-73. View PubMed Singh RJ, Feix JB, Mchaourab HS, Hogg N, Kalyanaraman B. Spin-labeling study of the oxidative damage to low-density lipoprotein. Arch Biochem Biophys. 1995 Jun 20; 320(1):155-61. View PubMed Singh RJ, Hogg N, Neese F, Joseph J, Kalyanaraman B. Trapping of nitric oxide formed during photolysis of sodium nitroprusside in aqueous and lipid phases: an electron spin resonance study. Photochem Photobiol. 1995 Apr; 61(4):325-30. View PubMed Singh RJ, Hogg N, Joseph J, Kalyanaraman B. Photosensitized decomposition of S-nitrosothiols and 2-methyl-2-nitrosopropane. Possible use for site-directed nitric oxide production. FEBS Lett. 1995 Feb 20; 360(1):47-51. View PubMed Hogg N, Singh RJ, Joseph J, Neese F, Kalyanaraman B. Reactions of nitric oxide with nitronyl nitroxides and oxygen: prediction of nitrite and nitrate formation by kinetic simulation. Free Radic Res. 1995 Jan; 22(1):47-56. View PubMed Singh RJ, Hogg N, Mchaourab HS, Kalyanaraman B. Physical and chemical interactions between nitric oxide and nitroxides. Biochem Biophys Acta. 1994 Dec 15; 1201(3):437-41. View PubMed Sidhu MS, Bhatia PVK, Singh RJ. Photochemical reduction of uranyl ion with triarylphosphite in acetone. J Radioanal Nucl Chem Lett. 1994; 188(5):355-65. Sidhu MS, Bhatia PVK, Singh RJ. A facile approach to measure the bimolecular quenching constant for quenching the optically excited dioxouranium (VI) ion. Proc Nat Acad Sci India. 1994; 64:656-660. Kalyanaraman B, Ramanujam S, Singh RJ, Joseph J, Feix JB. Formation of 2,5-Dihydroxybenzoic acid during the reaction between O2 and salicylic acid: Analysis by ESR Oximetry and HPLC with electrochemical detection J Am Chem Soc. 1993; 115:4007-4012. Sidhu MS, Chahal P, Singh RJ. Quenching of excited uranyl ion during its photochemical reduction by triphenylphosphine: part III. Indian J Chem. 1993; 32A:517-20. Singh RJ, Feix JB, Kalyanaraman B. Photobleaching of merocyanine 540: involvement of singlet molecular oxygen. Photochem Photobiol. 1992 Apr; 55(4):483-9. View PubMed O'Brien JM, Singh RJ, Feix JB, Kalyanaraman B, Sieber F. Action spectra of the antileukemic and antiviral activities of merocyanine 540. Photochem Photobiol. 1991 Nov; 54(5):851-4. View PubMed Singh RJ, Feix JB, Pintar TJ, Girotti AW, Kalyanaraman B. Photodynamic action of merocyanine 540 in artificial bilayers and natural membranes: action spectra and quantum yields. Photochem Photobiol. 1991 Apr; 53(4):493-500. View PubMed Sandhu SS, Singh RJ, Chawla SK. Uranium (V) as an intermediate in the photochemical reduction of uranyl ion with dicyclohexylsulphide. J Photochem Photobiol A: Chemistry. 1990; 52:65-68. Sidhu MS, Singh RJ, Sandhu SS. A new method for the evaluation physical bimolecular deactivation constants. J Chem Edu. 1990; 67:622. Sidhu MS, Singh RJ, Sarkaria P, Sandhu SS. Effect of aromatic molecules on the photochemical reduction of uranyl ion with triphenylphosphine. J Photochem Photobiol. 1989; 46:221-6. Sandhu SS, Sidhu MS, Singh RJ. Photochemical reduction of uranyl ion with trimethylphosphite. J Photochem Photobiol A: Chemistry. 1989; 46:213-219. Sandhu SS, Sidhu MS, Singh RJ. Luminescence study of uranyl trimethylacetate.dihydrate and Stern-Volmer quenching constants with various substrates in dry and aqueous acetone. J Photochem Photobiol. 1988; 42:251-59. Sandhu SS, Sidhu MS, Singh RJ. Study of the photoreduction of uranyl ion by triphenylphosphine, triphenylarsine, tri-p-tolylphosphine and tri-p-tolylarsine in acetone. J Photochem Photobiol. 1987; 39:229-37. PST-20513191 الصفحة الرئيسية المنشورات