البحث عن طبيب

Leland S. Hu, M.D.

  1. Radiologist
طلب موعد

المنشورات

  1. Sarkaria JN, Ballman KV, Kizilbash SH, Sulman EP, Giannini C, Friday BB, Butowski NA, Mohile NA, Piccioni DE, Battiste JD, Drappatz J, Campian JL, Mashru S, Jaeckle KA, O'Brien BJ, Dixon JG, Kabat BF, Laack NL, Hu LS, Kaufmann T, Kumthekar P, Ellingson BM, Anderson SK, Galanis E. Efficacy of Adding Veliparib to Temozolomide for Patients With MGMT-Methylated Glioblastoma: A Randomized Clinical Trial. JAMA Oncol. 2024 Dec 1; 10 (12):1637-1644
    View PubMed
  2. Vora S, Pafundi D, Voss M, Buras M, Ashman J, Bendok B, Breen W, Hu L, Kizilbash S, Laack N, Liu W, Mahajan A, Mrugala M, Porter A, Ruff M, Sio T, Uhm J, Yang M, Brinkmann D, Brown P. Short-course hypofractionated proton beam therapy, incorporating (18)F-DOPA PET and contrast-enhanced MRI targeting, for patients aged 65 years and older with newly diagnosed glioblastoma: a single-arm phase 2 trial. Lancet Oncol. 2024 Dec; 25 (12):1625-1634 Epub 2024 Nov 18
    View PubMed
  3. Shiroishi MS, Erickson BJ, Hu LS, Barboriak DP, Becerra L, Bell LC, Boss MA, Boxerman JL, Cen S, Cimino L, Fan Z, Keenan KE, Kirsch JE, Ameli N, Nazemi S, Quarles CC, Rosen MA, Rodriguez L, Schmainda KM, Zahlmann G, Zhou Y, Obuchowski N, Wu O, RSNA QIBA Dynamic Susceptibility Contrast MRI Biomarker Committee. The QIBA Profile for Dynamic Susceptibility Contrast MRI Quantitative Imaging Biomarkers for Assessing Gliomas. Radiology. 2024 Dec; 313 (3):e232555
    View PubMed
  4. Wang H, Argenziano MG, Yoon H, Boyett D, Save A, Petridis P, Savage W, Jackson P, Hawkins-Daarud A, Tran N, Hu L, Singleton KW, Paulson L, Dalahmah OA, Bruce JN, Grinband J, Swanson KR, Canoll P, Li J. Biologically informed deep neural networks provide quantitative assessment of intratumoral heterogeneity in post treatment glioblastoma. NPJ Digit Med. 2024 Oct 19; 7 (1):292
    View PubMed
  5. Loizzo SK, Prah MA, Kong MJ, Phung D, Urcuyo JC, Ye J, Attenello FJ, Mendoza J, Zhou Y, Shiroishi MS, Hu LS, Schmainda KM. Multi-Site Benchmark Study for Standardized Relative Cerebral Blood Volume in Untreated Brain Metastases Using the DSC-MRI Consensus Acquisition Protocol. AJNR Am J Neuroradiol. 2024 Oct 10 [Epub ahead of print]
    View PubMed
  6. Anil A, Stokes AM, Karis JP, Bell LC, Eschbacher J, Jennings K, Prah MA, Hu LS, Boxerman JL, Schmainda KM, Quarles CC. Identification of a Single-Dose, Low-Flip-Angle-Based CBV Threshold for Fractional Tumor Burden Mapping in Recurrent Glioblastoma. AJNR Am J Neuroradiol. 2024 Oct 3; 45 (10):1545-1551 Epub 2024 Oct 03
    View PubMed
  7. Vora SA, Pafundi DH, Voss MM, Buras MR, Ashman JB, Bendok BR, Breen W, Hu LS, Kizilbash SH, Laack NN, Liu W, Mahajan A, Mrugala MM, Porter Umphrey AB, Ruff MW, Sio TT, Uhm J, Yang M, Brinkmann DH, Brown PD. Phase 2 Study of Short-Course, Hypofractionated Proton Beam Therapy Incorporating 18F-DOPA PET–MRI for Older Patients With Newly Diagnosed Glioblastoma (In review with Editor, Manuscript Number: D-24-00665R1) The Lancet. 2024.
  8. Shalom ES, Kim H, van der Heijden RA, Ahmed Z, Patel R, Hormuth DA 2nd, DiCarlo JC, Yankeelov TE, Sisco NJ, Dortch RD, Stokes AM, Inglese M, Grech-Sollars M, Toschi N, Sahoo P, Singh A, Verma SK, Rathore DK, Kazerouni AS, Partridge SC, LoCastro E, Paudyal R, Wolansky IA, Shukla-Dave A, Schouten P, Gurney-Champion OJ, Jirik R, Macicek O, Bartos M, Vitous J, Das AB, Kim SG, Bokacheva L, Mikheev A, Rusinek H, Berks M, Hubbard Cristinacce PL, Little RA, Cheung S, O'Connor JPB, Parker GJM, Moloney B, LaViolette PS, Bobholz S, Duenweg S, Virostko J, Laue HO, Sung K, Nabavizadeh A, Saligheh Rad H, Hu LS, Sourbron S, Bell LC, Fathi Kazerooni A. The ISMRM Open Science Initiative for Perfusion Imaging (OSIPI): Results from the OSIPI-Dynamic Contrast-Enhanced challenge. Magn Reson Med. 2024 May; 91 (5):1803-1821 Epub 2023 Dec 19
    View PubMed
  9. Hu LS, Smits M, Kaufmann TJ, Knutsson L, Rapalino O, Galldiks N, Sundgrene PC, Cha S. Advanced Imaging in the Diagnosis and Response Assessment of High-Grade Glioma: AJR Expert Panel Narrative Review. AJR Am J Roentgenol. 2024 Mar 13 [Epub ahead of print]
    View PubMed
  10. Wang L, Wang H, D'Angelo F, Curtin L, Sereduk CP, Leon G, Singleton KW, Urcuyo J, Hawkins-Daarud A, Jackson PR, Krishna C, Zimmerman RS, Patra DP, Bendok BR, Smith KA, Nakaji P, Donev K, Baxter LC, Mrugala MM, Ceccarelli M, Iavarone A, Swanson KR, Tran NL, Hu LS#, Li J#. Quantifying intra-tumoral genetic heterogeneity of glioblastoma toward precision medicine using MRI and a data-inclusive machine learning algorithm. PLoS One. 2024; 19 (4):e0299267 Epub 2024 Apr 03
    View PubMed
  11. Mao L, Wang L, Hu LS, Eschbacher JM, Leon GD, Singleton KW, Curtin LA, Urcuyo J, Sereduk C, Tran NL, Hawkins-Daarud A, Swanson KR, Li J. Weakly-supervised transfer learning with application in precision medicine. IEEE Transactions on Automation Science and Engineering. 2023 Oct; 1-15.
  12. Hu LS, D'Angelo F, Weiskittel TM, Caruso FP, Fortin Ensign SP, Blomquist MR, Flick MJ, Wang L, Sereduk CP, Meng-Lin K, De Leon G, Nespodzany A, Urcuyo JC, Gonzales AC, Curtin L, Lewis EM, Singleton KW, Dondlinger T, Anil A, Semmineh NB, Noviello T, Patel RA, Wang P, Wang J, Eschbacher JM, Hawkins-Daarud A, Jackson PR, Grunfeld IS, Elrod C, Mazza GL, McGee SC, Paulson L, Clark-Swanson K, Lassiter-Morris Y, Smith KA, Nakaji P, Bendok BR, Zimmerman RS, Krishna C, Patra DP, Patel NP, Lyons M, Neal M, Donev K, Mrugala MM, Porter AB, Beeman SC, Jensen TR, Schmainda KM, Zhou Y, Baxter LC, Plaisier CL, Li J, Li H, Lasorella A, Quarles CC, Swanson KR, Ceccarelli M, Iavarone A, Tran NL. Integrated molecular and multiparametric MRI mapping of high-grade glioma identifies regional biologic signatures. Nat Commun. 2023 Sep 28; 14 (1):6066 Epub 2023 Sept 28
    View PubMed
  13. Baxter LC, Limback-Stokin M, Patten KJ, Arreola AC, Locke DEC, Hu L, Zhou Y, Caselli RJ. Hippocampal connectivity and memory decline in cognitively intact APOE epsilon4 carriers. Alzheimers Dement. 2023 Sep; 19 (9):3806-3814 Epub 2023 Mar 12
    View PubMed
  14. Ferreri AJM, Calimeri T, Cwynarski K, Dietrich J, Grommes C, Hoang-Xuan K, Hu LS, Illerhaus G, Nayak L, Ponzoni M, Batchelor TT. Primary central nervous system lymphoma. Nat Rev Dis Primers. 2023 Jun 15; 9 (1):29 Epub 2023 June 15
    View PubMed
  15. Turcotte EL, Jones BA, Chhabra N, Porter AB, Donev K, Hu LS, Bendok BR. Awake Microsurgical Resection of a Motor Cortex Glioma With Cortical and Subcortical Motor Mapping, Image Guidance, and Augmented Reality: 2-Dimensional Operative Video. Oper Neurosurg (Hagerstown). 2023 Feb 1; 24 (2):e122 Epub 2022 Nov 28
    View PubMed
  16. Urcuyo JC, Curtin L, Langworthy JM, De Leon G, Anderies B, Singleton KW, Hawkins-Daarud A, Jackson PR, Bond KM, Ranjbar S, Lassiter-Morris Y, Clark-Swanson KR, Paulson LE, Sereduk C, Mrugala MM, Porter AB, Baxter L, Salomao M, Donev K, Hudson M, Meyer J, Zeeshan Q, Sattur M, Patra DP, Jones BA, Rahme RJ, Neal MT, Patel N, Kouloumberis P, Turkmani AH, Lyons M, Krishna C, Zimmerman RS, Bendok BR, Tran NL, Hu LS, Swanson KR. Image-localized biopsy mapping of brain tumor heterogeneity: A single-center study protocol. PLoS One. 2023; 18 (12):e0287767 Epub 2023 Dec 20
    View PubMed
  17. Bond KM, Curtin L, Ranjbar S, Afshari AE, Hu LS, Rubin JB, Swanson KR. An image-based modeling framework for predicting spatiotemporal brain cancer biology within individual patients. Front Oncol. 2023; 13:1185738 Epub 2023 Oct 02
    View PubMed
  18. Shiroishi MS, Weinert D, Cen SY, Varghese B, Dondlinger T, Prah M, Mendoza J, Nazemi S, Ameli N, Amini N, Shohas S, Chen S, Bigjahan B, Zada G, Chen T, Neman-Ebrahim J, Chang EL, Chow FE, Fan Z, Yang W, Attenello FJ, Ye J, Kim PE, Patel VN, Lerner A, Acharya J, Hu LS, Quarles CC, Boxerman JL, Wu O, Schmainda KM. A cross-sectional study to test equivalence of low- versus intermediate-flip angle dynamic susceptibility contrast MRI measures of relative cerebral blood volume in patients with high-grade gliomas at 1.5 Tesla field strength. Front Oncol. 2023; 13:1156843 Epub 2023 Sept 20
    View PubMed
  19. Anil A, Stokes AM, Chao R, Hu LS, Alhilali L, Karis JP, Bell LC, Quarles CC. Identification of single-dose, dual-echo based CBV threshold for fractional tumor burden mapping in recurrent glioblastoma. Front Oncol. 2023; 13:1046629 Epub 2023 Jan 17
    View PubMed
  20. Aizer AA, Lamba N, Ahluwalia MS, Aldape K, Boire A, Brastianos PK, Brown PD, Camidge DR, Chiang VL, Davies MA, Hu LS, Huang RY, Kaufmann T, Kumthekar P, Lam K, Lee EQ, Lin NU, Mehta M, Parsons M, Reardon DA, Sheehan J, Soffietti R, Tawbi H, Weller M, Wen PY. Brain metastases: A Society for Neuro-Oncology (SNO) consensus review on current management and future directions. Neuro Oncol. 2022 Oct 3; 24 (10):1613-1646
    View PubMed
  21. Wang L, Hawkins-Daarud A, Swanson KR, Hu LS, Li J. Knowledge-infused Global-Local Data Fusion for Spatial Predictive Modeling in Precision Medicine. IEEE Trans Autom Sci Eng. 2022 Jul; 19 (3):2203-2215 Epub 2021 May 13
    View PubMed
  22. Mahajan A, Shih H, Penas-Prado M, Ligon K, Aldape K, Hu LS, Loughan AR, Basso MR, Leeper HE, Nahed BV, Stott SL, Geyer S, Giannini C, Galanis E. The Alliance AMBUSH Trial: Rationale and Design. Cancers (Basel). 2022 Jan 14; 14 (2)
    View PubMed
  23. Ranjbar S, Singleton KW, Curtin L, Rickertsen CR, Paulson LE, Hu LS, Mitchell JR, Swanson KR. Weakly Supervised Skull Stripping of Magnetic Resonance Imaging of Brain Tumor Patients. Front Neuroimaging. 2022; 1:832512 Epub 2022 Apr 25
    View PubMed
  24. Malik DG, Rath TJ, Urcuyo Acevedo JC, Canoll PD, Swanson KR, Boxerman JL, Quarles CC, Schmainda KM, Burns TC, Hu LS. Advanced MRI Protocols to Discriminate Glioma From Treatment Effects: State of the Art and Future Directions. Front Radiol. 2022; 2:809373 Epub 2022 Apr 15
    View PubMed
  25. Curtin L, Whitmire P, White H, Bond KM, Mrugala MM, Hu LS, Swanson KR. Shape matters: morphological metrics of glioblastoma imaging abnormalities as biomarkers of prognosis. Sci Rep. 2021 Dec 1; 11 (1):23202 Epub 2021 Dec 01
    View PubMed
  26. Stokes AM, Bergamino M, Alhilali L, Hu LS, Karis JP, Baxter LC, Bell LC, Quarles CC. Evaluation of single bolus, dual-echo dynamic susceptibility contrast MRI protocols in brain tumor patients. J Cereb Blood Flow Metab. 2021 Dec; 41 (12):3378-3390 Epub 2021 Aug 20
    View PubMed
  27. Ambady P, Hu LS, Politi LS, Anzalone N, Barajas RF Jr. Primary central nervous system lymphoma: advances in MRI and PET imaging. Ann Lymphoma. 2021 Sep; 5 Epub 2021 Sept 30
    View PubMed
  28. Barajas RF, Politi LS, Anzalone N, Schoder H, Fox CP, Boxerman JL, Kaufmann TJ, Quarles CC, Ellingson BM, Auer D, Andronesi OC, Ferreri AJM, Mrugala MM, Grommes C, Neuwelt EA, Ambady P, Rubenstein JL, Illerhaus G, Nagane M, Batchelor TT, Hu LS. Consensus recommendations for MRI and PET imaging of primary central nervous system lymphoma: guideline statement from the International Primary CNS Lymphoma Collaborative Group (IPCG). Neuro Oncol. 2021 Jul 1; 23 (7):1056-1071
    View PubMed
  29. Tomblinson CM, Fletcher GP, Hu LS, Mi L, Howard BE, Nagel TH, Hinni ML, Hoxworth JM. Determination of posterolateral oropharyngeal wall thickness and the potential implications for transoral surgical margins in tonsil cancer. Head Neck. 2021 Jul; 43 (7):2185-2192 Epub 2021 Mar 29
    View PubMed
  30. Hu LS, Wang L, Hawkins-Daarud A, Eschbacher JM, Singleton KW, Jackson PR, Clark-Swanson K, Sereduk CP, Peng S, Wang P, Wang J, Baxter LC, Smith KA, Mazza GL, Stokes AM, Bendok BR, Zimmerman RS, Krishna C, Porter AB, Mrugala MM, Hoxworth JM, Wu T, Tran NL, Swanson KR, Li J. Uncertainty quantification in the radiogenomics modeling of EGFR amplification in glioblastoma. Sci Rep. 2021 Feb 16; 11 (1):3932
    View PubMed
  31. Massey SC, Whitmire P, Doyle TE, Ippolito JE, Mrugala MM, Hu LS, Canoll P, Anderson ARA, Wilson MA, Fitzpatrick SM, McCarthy MM, Rubin JB, Swanson KR. Sex differences in health and disease: A review of biological sex differences relevant to cancer with a spotlight on glioma. Cancer Lett. 2021 Feb 1; 498:178-187 Epub 2020 Oct 29
    View PubMed
  32. Boxerman JL, Quarles CC, Hu LS, Erickson BJ, Gerstner ER, Smits M, Kaufmann TJ, Barboriak DP, Huang RH, Wick W, Weller M, Galanis E, Kalpathy-Cramer J, Shankar L, Jacobs P, Chung C, van den Bent MJ, Chang S, Al Yung WK, Cloughesy TF, Wen PY, Gilbert MR, Rosen BR, Ellingson BM, Schmainda KM, Jumpstarting Brain Tumor Drug Development Coalition Imaging Standardization Steering Committee. Consensus recommendations for a dynamic susceptibility contrast MRI protocol for use in high-grade gliomas. Neuro Oncol. 2020 Sep 29; 22 (9):1262-1275
    View PubMed
  33. Mitchell JR, Kamnitsas K, Singleton KW, Whitmire SA, Clark-Swanson KR, Ranjbar S, Rickertsen CR, Johnston SK, Egan KM, Rollison DE, Arrington J, Krecke KN, Passe TJ, Verdoorn JT, Nagelschneider AA, Carr CM, Port JD, Patton A, Campeau NG, Liebo GB, Eckel LJ, Wood CP, Hunt CH, Vibhute P, Nelson KD, Hoxworth JM, Patel AC, Chong BW, Ross JS, Boxerman JL, Vogelbaum MA, Hu LS, Glocker B, Swanson KR. Deep neural network to locate and segment brain tumors outperformed the expert technicians who created the training data. J Med Imaging (Bellingham). 2020 Sep; 7 (5):055501 Epub 2020 Oct 16
    View PubMed
  34. Morris B, Curtin L, Hawkins-Daarud A, Hubbard ME, Rahman R, Smith SJ, Auer D, Tran NL, Hu LS, Eschbacher JM, Smith KA, Stokes A, Swanson KR, Owen MR. Identifying the spatial and temporal dynamics of molecularly-distinct glioblastoma sub-populations. Math Biosci Eng. 2020 Jul 16; 17 (5):4905-4941
    View PubMed
  35. Hu LS, Swanson KR. Roadmap for the clinical integration of radiomics in neuro-oncology. Neuro Oncol 2020 Jun 9; 22 (6):743-745
    View PubMed
  36. Bell LC, Semmineh N, An H, Eldeniz C, Wahl R, Schmainda KM, Prah MA, Erickson BJ, Korfiatis P, Wu C, Sorace AG, Yankeelov TE, Rutledge N, Chenevert TL, Malyarenko D, Liu Y, Brenner A, Hu LS, Zhou Y, Boxerman JL, Yen YF, Kalpathy-Cramer J, Beers AL, Muzi M, Madhuranthakam AJ, Pinho M, Johnson B, Quarles CC. Evaluating the Use of rCBV as a Tumor Grade and Treatment Response Classifier Across NCI Quantitative Imaging Network Sites: Part II of the DSC-MRI Digital Reference Object (DRO) Challenge. Tomography. 2020 Jun; 6 (2):203-208
    View PubMed
  37. Whitmire P, Rickertsen CR, Hawkins-Daarud A, Carrasco E Jr, Lorence J, De Leon G, Curtin L, Bayless S, Clark-Swanson K, Peeri NC, Corpuz C, Lewis-de Los Angeles CP, Bendok BR, Gonzalez-Cuyar L, Vora S, Mrugala MM, Hu LS, Wang L, Porter A, Kumthekar P, Johnston SK, Egan KM, Gatenby R, Canoll P, Rubin JB, Swanson KR. Sex-specific impact of patterns of imageable tumor growth on survival of primary glioblastoma patients. BMC Cancer. 2020 May 19; 20 (1):447
    View PubMed
  38. Hu LS, Hawkins-Daarud A, Wang L, Li J, Swanson KR. Imaging of intratumoral heterogeneity in high-grade glioma. Cancer Lett. 2020 May 1; 477:97-106 Epub 2020 Feb 27
    View PubMed
  39. Ranjbar S, Singleton KW, Jackson PR, Rickertsen CR, Whitmire SA, Clark-Swanson KR, Mitchell JR, Swanson KR, Hu LS. A Deep Convolutional Neural Network for Annotation of Magnetic Resonance Imaging Sequence Type. J Digit Imaging. 2020 Apr; 33 (2):439-446
    View PubMed
  40. Hu LS, Brat DJ, Bloch O, Ramkissoon S, Lesser GJ. The Practical Application of Emerging Technologies Influencing the Diagnosis and Care of Patients With Primary Brain Tumors. Am Soc Clin Oncol Educ Book. 2020 Mar; 40:1-12
    View PubMed
  41. Hoxworth JM, Eschbacher JM, Gonzales AC, Singleton KW, Leon GD, Smith KA, Stokes AM, Zhou Y, Mazza GL, Porter AB, Mrugala MM, Zimmerman RS, Bendok BR, Patra DP, Krishna C, Boxerman JL, Baxter LC, Swanson KR, Quarles CC, Schmainda KM, Hu LS. Performance of Standardized Relative CBV for Quantifying Regional Histologic Tumor Burden in Recurrent High-Grade Glioma: Comparison against Normalized Relative CBV Using Image-Localized Stereotactic Biopsies. AJNR Am J Neuroradiol. 2020 Mar; 41 (3):408-415 Epub 2020 Mar 12
    View PubMed
  42. Massey SC, White H, Whitmire P, Doyle T, Johnston SK, Singleton KW, Jackson PR, Hawkins-Daarud A, Bendok BR, Porter AB, Vora S, Sarkaria JN, Hu LS, Mrugala MM, Swanson KR. Image-based metric of invasiveness predicts response to adjuvant temozolomide for primary glioblastoma. PLoS One. 2020; 15 (3):e0230492 Epub 2020 Mar 27
    View PubMed
  43. Singleton KW, Porter AB, Hu LS, Johnston SK, Bond KM, Rickertsen CR, De Leon G, Whitmire SA, Clark-Swanson KR, Mrugala MM, Swanson KR. Days gained response discriminates treatment response in patients with recurrent glioblastoma receiving bevacizumab-based therapies. Neurooncol Adv. 2020 Jan-Dec; 2 (1):vdaa085 Epub 2020 July 09
    View PubMed
  44. Curtin L, Whitmire P, Rickertsen CR, Mazza GL, Canoll P, Johnston SK, Mrugala MM, Swanson KR, Hu LS. Assessment of Prognostic Value of Cystic Features in Glioblastoma Relative to Sex and Treatment With Standard-of-Care. Front Oncol. 2020; 10:580750 Epub 2020 Nov 16
    View PubMed
  45. Johnston SK, Whitmire P, Massey SC, Kumthekar P, Porter AB, Raghunand N, Gonzalez-Cuyar LF, Mrugala MM, Hawkins-Daarud A, Jackson PR, Hu LS, Sarkaria JN, Wang L, Gatenby RA, Egan KM, Canoll P, Swanson KR, ENDURES consortium. ENvironmental Dynamics Underlying Responsive Extreme Survivors (ENDURES) of Glioblastoma: A Multidisciplinary Team-based, Multifactorial Analytical Approach. Am J Clin Oncol. 2019 Aug; 42 (8):655-661
    View PubMed
  46. Gaw N, Hawkins-Daarud A, Hu LS, Yoon H, Wang L, Xu Y, Jackson PR, Singleton KW, Baxter LC, Eschbacher J, Gonzales A, Nespodzany A, Smith K, Nakaji P, Mitchell JR, Wu T, Swanson KR, Li J. Integration of machine learning and mechanistic models accurately predicts variation in cell density of glioblastoma using multiparametric MRI. Sci Rep. 2019 Jul 11; 9 (1):10063 Epub 2019 July 11
    View PubMed
  47. Schmainda KM, Prah MA, Hu LS, Quarles CC, Semmineh N, Rand SD, Connelly JM, Anderies B, Zhou Y, Zhou Y, Liu Y, Logan B, Stokes A, Baird G, Boxerman JL. Moving Toward a Consensus DSC-MRI Protocol: Validation of a Low-Flip Angle Single-Dose Option as a Reference Standard for Brain Tumors. AJNR Am J Neuroradiol. 2019 Apr; 40 (4):626-633 Epub 2019 Mar 28
    View PubMed
  48. Hu LS, Yoon H, Eschbacher JM, Baxter LC, Dueck AC, Nespodzany A, Smith KA, Nakaji P, Xu Y, Wang L, Karis JP, Hawkins-Daarud AJ, Singleton KW, Jackson PR, Anderies BJ, Bendok BR, Zimmerman RS, Quarles C, Porter-Umphrey AB, Mrugala MM, Sharma A, Hoxworth JM, Sattur MG, Sanai N, Koulemberis PE, Krishna C, Mitchell JR, Wu T, Tran NL, Swanson KR, Li J. Accurate Patient-Specific Machine Learning Models of Glioblastoma Invasion Using Transfer Learning. AJNR Am J Neuroradiol. 2019 Mar; 40 (3):418-425 Epub 2019 Feb 28
    View PubMed
  49. Bell LC, Semmineh N, An H, Eldeniz C, Wahl R, Schmainda KM, Prah MA, Erickson BJ, Korfiatis P, Wu C, Sorace AG, Yankeelov TE, Rutledge N, Chenevert TL, Malyarenko D, Liu Y, Brenner A, Hu LS, Zhou Y, Boxerman JL, Yen YF, Kalpathy-Cramer J, Beers AL, Muzi M, Madhuranthakam AJ, Pinho M, Johnson B, Quarles CC. Evaluating Multisite rCBV Consistency from DSC-MRI Imaging Protocols and Postprocessing Software Across the NCI Quantitative Imaging Network Sites Using a Digital Reference Object (DRO). Tomography. 2019 Mar; 5(1):110-117.
    View PubMed
  50. Dhamija R, Wood CP, Porter AB, Hu LS, Weindling SM, Hoxworth JM. Updated Imaging Features of Dysplastic Cerebellar Gangliocytoma. J Comput Assist Tomogr. 2019 Mar/Apr; 43 (2):277-281
    View PubMed
  51. Rayfield CA, Grady F, De Leon G, Rockne R, Carrasco E, Jackson P, Vora M, Johnston SK, Hawkins-Daarud A, Clark-Swanson KR, Whitmire S, Gamez ME, Porter A, Hu L, Gonzalez-Cuyar L, Bendok B, Vora S, Swanson KR. Distinct Phenotypic Clusters of Glioblastoma Growth and Response Kinetics Predict Survival. JCO Clin Cancer Inform. 2018 Dec; 2:1-14.
    View PubMed
  52. Semmineh NB, Bell LC, Stokes AM, Hu LS, Boxerman JL, Quarles CC. Optimization of Acquisition and Analysis Methods for Clinical Dynamic Susceptibility Contrast MRI Using a Population-Based Digital Reference Object. AJNR Am J Neuroradiol. 2018 Nov; 39 (11):1981-1988 Epub 2018 Oct 11
    View PubMed
  53. Dhamija R, Weindling SM, Porter AB, Hu LS, Wood CP, Hoxworth JM. Neuroimaging abnormalities in patients with Cowden syndrome: Retrospective single-center study. Neurol Clin Pract. 2018 Jun; 8 (3):207-213
    View PubMed
  54. Schmainda KM, Prah MA, Rand SD, Liu Y, Logan B, Muzi M, Rane SD, Da X, Yen YF, Kalpathy-Cramer J, Chenevert TL, Hoff B, Ross B, Cao Y, Aryal MP, Erickson B, Korfiatis P, Dondlinger T, Bell L, Hu L, Kinahan PE, Quarles CC. Multisite Concordance of DSC-MRI Analysis for Brain Tumors: Results of a National Cancer Institute Quantitative Imaging Network Collaborative Project. AJNR Am J Neuroradiol. 2018 Jun; 39 (6):1008-1016 Epub 2018 May 24
    View PubMed
  55. Sarkaria JN, Hu LS, Parney IF, Pafundi DH, Brinkmann DH, Laack NN, Giannini C, Burns TC, Kizilbash SH, Laramy JK, Swanson KR, Kaufmann TJ, Brown PD, Agar NYR, Galanis E, Buckner JC, Elmquist WF. Is the blood-brain barrier really disrupted in all glioblastomas? A critical assessment of existing clinical data. Neuro Oncol. 2018 Jan 22; 20 (2):184-191
    View PubMed
  56. Tomblinson CM, Nagel TH, Hu LS, Zarka MA, Hoxworth JM. Median Lingual Lymph Nodes: Prevalence on Imaging and Potential Implications for Oral Cavity Cancer Staging. J Comput Assist Tomogr. 2017 Jul/Aug; 41 (4):528-534
    View PubMed
  57. Bell LC, Hu LS, Stokes AM, McGee SC, Baxter LC, Quarles CC. Characterizing the Influence of Preload Dosing on Percent Signal Recovery (PSR) and Cerebral Blood Volume (CBV) Measurements in a Patient Population With High-Grade Glioma Using Dynamic Susceptibility Contrast MRI. Tomography. 2017 Jun; 3 (2):89-95
    View PubMed
  58. Hu LS, Ning S, Eschbacher JM, Baxter LC, Gaw N, Ranjbar S, Plasencia J, Dueck AC, Peng S, Smith KA, Nakaji P, Karis JP, Quarles CC, Wu T, Loftus JC, Jenkins RB, Sicotte H, Kollmeyer TM, O'Neill BP, Elmquist W, Hoxworth JM, Frakes D, Sarkaria J, Swanson KR, Tran NL, Li J, Mitchell JR. Radiogenomics to characterize regional genetic heterogeneity in glioblastoma. Neuro Oncol. 2017 Jan; 19 (1):128-137 Epub 2016 Aug 08
    View PubMed
  59. Korfiatis P, Kline TL, Kelm ZS, Carter RE, Hu LS, Erickson BJ. Dynamic Susceptibility Contrast-MRI Quantification Software Tool: Development and Evaluation. Tomography. 2016 Dec; 2 (4):448-456
    View PubMed
  60. Plasencia JD, Hu LS, Turner GH, Bennett KM, Frakes DH. Design and verification of novel low-cost mr-guided small-animal stereotactic system Journal Of Medical And Biological Engineering. 2016 Aug; 36(4):526-35. Epub 1900 Jan 01.
  61. Hu LS, Kelm Z, Korfiatis P, Dueck AC, Elrod C, Ellingson BM, Kaufmann TJ, Eschbacher JM, Karis JP, Smith K, Nakaji P, Brinkman D, Pafundi D, Baxter LC, Erickson BJ. Impact of Software Modeling on the Accuracy of Perfusion MRI in Glioma. AJNR Am J Neuroradiol. 2015 Dec; 36 (12):2242-9 Epub 2015 Sept 10
    View PubMed
  62. Hu LS, Ning S, Eschbacher JM, Gaw N, Dueck AC, Smith KA, Nakaji P, Plasencia J, Ranjbar S, Price SJ, Tran N, Loftus J, Jenkins R, O'Neill BP, Elmquist W, Baxter LC, Gao F, Frakes D, Karis JP, Zwart C, Swanson KR, Sarkaria J, Wu T, Mitchell JR, Li J. Multi-Parametric MRI and Texture Analysis to Visualize Spatial Histologic Heterogeneity and Tumor Extent in Glioblastoma. PLoS One. 2015; 10 (11):e0141506 Epub 2015 Nov 24
    View PubMed
  63. Pafundi DH, Laack NN, Youland RS, Parney IF, Lowe VJ, Giannini C, Kemp BJ, Grams MP, Morris JM, Hoover JM, Hu LS, Sarkaria JN, Brinkmann DH. Biopsy validation of 18F-DOPA PET and biodistribution in gliomas for neurosurgical planning and radiotherapy target delineation: results of a prospective pilot study. Neuro Oncol. 2013 Aug; 15 (8):1058-67 Epub 2013 Mar 03
    View PubMed
  64. Lehman VT, Luetmer PH, Sorenson EJ, Carter RE, Gupta V, Fletcher GP, Hu LS, Kotsenas AL. Cervical spine MR imaging findings of patients with Hirayama disease in North America: a multisite study. AJNR Am J Neuroradiol. 2013 Feb; 34 (2):451-6 Epub 2012 Aug 09
    View PubMed
  65. Hu LS, Eschbacher JM, Heiserman JE, Dueck AC, Shapiro WR, Liu S, Karis JP, Smith KA, Coons SW, Nakaji P, Spetzler RF, Feuerstein BG, Debbins J, Baxter LC. Reevaluating the imaging definition of tumor progression: perfusion MRI quantifies recurrent glioblastoma tumor fraction, pseudoprogression, and radiation necrosis to predict survival. Neuro Oncol. 2012 Jul; 14 (7):919-30 Epub 2012 May 03
    View PubMed
  66. Hu LS, Eschbacher JM, Dueck AC, Heiserman JE, Liu S, Karis JP, Smith KA, Shapiro WR, Pinnaduwage DS, Coons SW, Nakaji P, Debbins J, Feuerstein BG, Baxter LC. Correlations between perfusion MR imaging cerebral blood volume, microvessel quantification, and clinical outcome using stereotactic analysis in recurrent high-grade glioma. AJNR Am J Neuroradiol. 2012 Jan; 33 (1):69-76 Epub 2011 Nov 17
    View PubMed
  67. Little AS, Liu S, Beeman S, Sankar T, Preul MC, Hu LS, Smith KA, Baxter LC. Brain retraction and thickness of cerebral neocortex: an automated technique for detecting retraction-induced anatomic changes using magnetic resonance imaging. Neurosurgery. 2010 Sep; 67(3 Suppl Operative):ons277-82; discussion ons282.
    View PubMed
  68. Shih P, Pinnaduwage T, Hu LS, Spetzler RF. A pediatric patient with a dissecting thrombotic anterior choroidal artery aneurysm: case report. Neurosurgery. 2010 Aug; 67(2):E518.
    View PubMed
  69. Hu LS, Baxter LC, Pinnaduwage DS, Paine TL, Karis JP, Feuerstein BG, Schmainda KM, Dueck AC, Debbins J, Smith KA, Nakaji P, Eschbacher JM, Coons SW, Heiserman JE. Optimized preload leakage-correction methods to improve the diagnostic accuracy of dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging in posttreatment gliomas. AJNR Am J Neuroradiol. 2010 Jan; 31 (1):40-8 Epub 2009 Sept 12
    View PubMed
  70. Hu LS, Baxter LC, Smith KA, Feuerstein BG, Karis JP, Eschbacher JM, Coons SW, Nakaji P, Yeh RF, Debbins J, Heiserman JE. Relative cerebral blood volume values to differentiate high-grade glioma recurrence from posttreatment radiation effect: direct correlation between image-guided tissue histopathology and localized dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging measurements. AJNR Am J Neuroradiol. 2009 Mar; 30 (3):552-8 Epub 2008 Dec 04
    View PubMed
  71. Hu LS, Caire J, Twickler DM. MR findings of complicated multifetal gestations. Pediatr Radiol. 2006 Jan; 36(1):76-81. Epub 2005 Nov 12.
    View PubMed