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Daniel M. Frendl, M.D., Ph.D.

  1. Urologist

Location

  1. Phoenix, Arizona

Languages

EnglishHungarian

Daniel M. Frendl, M.D., Ph.D., is a urologist with an interest in prostate cancer, benign prostatic hyperplasia, and prostate health. He is a urologic surgeon with a clinical practice that includes:

  • Prostate cancer diagnosis: transperineal prostate biopsy with magnetic resonance imaging and ultrasound fusion
  • Prostate ablation: Focal treatments for prostate cancer including high intensity focused ultrasound (HIFU), Irreversible electroporation (NanoKnife), and clinical trials for other technologies
  • Salvage prostate ablation: Focal ablation of prostate cancer that is locally recurrent after radiation treatment
  • SpaceOAR and Barrigel rectal spacer placement for patients undergoing radiation for prostate cancer
  • Treatments for benign prostatic hyperplasia: Rezum, UroLift, and transurethral resection (TURP)
  • Biopsy and resection of nonmuscle invasive bladder and urothelial cancers
  • Inguinal, scrotal, and penile surgery including: hydrocelectomy, orchiectomy, vasectomy, circumcision
  • Ureteroscopy

Dr. Frendl is actively recruiting for the following clinical trials of focal therapy for prostate cancer:

  • Vapor2: a prospective multi-center, single-arm, clinical trial of transurethral water vapor ablation of Gleason Grade Group 2 (GS 3+4) prostate cancer using minimally invasive VanquishT Water Vapor Ablation. Eligible patients must have disease confined to a region surrounding an MRI visible PIRADS3 or PIRADS4 lesion

Mayo Clinic's Department of Urology is one of the few urology practices in Arizona that routinely performs transperineal prostate biopsies with advanced imaging guidance. Transperineal prostate biopsies enable more accurate detection of prostate cancer and offer a lower risk of infection than traditional transrectal biopsies. Dr. Frendl's practice specializes in the transperineal approach to prostate biopsy as well as focal treatments for prostate cancer.

In addition to his clinical practice, Dr. Frendl is also a health services researcher and is active in health policy advocacy through the American Urological Association. His current research focuses on assessing the efficacy of focal ablation treatments for prostate cancer and quality of life outcomes. Nationally, he is an active member of the Legislative Affairs Committee for the American Urological Association. Dr. Frendl received his M.D. and Ph.D. in Clinical and Population Health Research from the University of Massachusetts Medical School. He completed his training at the Massachusetts General Hospital — Harvard Urologic Surgery Residency Program. Dr. Frendl also completed a fellowship in Healthcare Policy and Administration with the Massachusetts General Hospital Physician's Organization.

  1. Bladder biopsy
  2. Cystoscopy
  3. Irreversible electroporation
  4. MRI-guided biopsy
  5. Orchiectomy
  6. Prostate ablation
  7. Prostate biopsy
  8. Prostate ultrasound
  9. Rectal hydrogel spacer placement
  10. Transurethral resection of the prostate
  11. Ultrasound-guided prostate biopsy
  12. Ultrasound-guided surgery
  13. Ureteroscopy
  1. 2022
    Resident - Urologic SurgeryMassachusetts General Hospital, Harvard Medical School
  2. 2020
    Fellow - Health Care Policy and AdministrationMassachusetts General Physicians Organization
  3. 2017
    Intern - General SurgeryMassachusetts General Hospital, Harvard Medical School
  4. 2016
    MD / PhD - Clinical and Population HealthUniversity of Massachusetts Medical School
  5. 2009
    MS - Physiology and BiophysicsGeorgetown University
  6. 2008
    BA - Public Policy StudiesDuke University

Certifications

  1. 2024
    Urological SurgeryAmerican Board of Urology

Awards and honors

  1. 2016
    Graduation with Highest Distinction in Public PolicyDuke University
  2. 2015
    InductionAlpha Omega Alpha Honor Medical Society
  3. 2013
    Student Travel AwardInternational Society for Pharmacoepidemiology
  4. 2008
    Student Travel AwardAmerican Stroke Association

Professional memberships

  1. 2022 - present
    MemberWestern Section, American Urological Association
  2. 2022 - present
    MemberEndourological Society
  3. 2022 - present
    MemberFocal Therapy Society
  4. 2021 - 2024
    MemberLegislative Affairs Committee, American Urological Association
  5. 2019 - 2020
    Advocacy FellowHoltgrewe Legislative Fellowship, American Urological Association
  6. 2017 - present
    MemberAmerican Urological Association
  7. 2014 - 2015
    MemberPublications Committee, Massachusetts Medical Society
  8. 2011 - 2012
    TrusteeBoard of Trustees, Massachusetts Medical Society
  9. 2010 - 2011
    Alternate TrusteeBoard of Trustees, Massachusetts Medical Society
  10. 2009 - present
    MemberAmerican Medical Association, Memberships

Publications