البحث عن طبيب

Bart L. Clarke, M.D.

طلب موعد

المنشورات

  1. Clarke BL, Khan AA, Rubin MR, Schwarz P, Vokes T, Shoback DM, Gagnon C, Palermo A, Abbott LG, Hofbauer LC, Kohlmeier L, Cetani F, Pihl S, An X, Smith AR, Lai B, Ukena J, Sibley CT, Shu AD, Rejnmark L. Efficacy and Safety of TransCon PTH in Adults with Hypoparathyroidism: 52-Week Results From the Phase 3 PaTHway Trial. J Clin Endocrinol Metab. 2024 Oct 8 Epub 2024 Oct 08
    View PubMed
  2. Hoong CWS, Broski SM, Sfeir JG, Clarke BL. Natural history and complications of normocalcemic hyperparathyroidism: a retrospective cohort study. JBMR Plus. 2024 Jul; 8 (7):ziae074 Epub 2024 May 31
    View PubMed
  3. Hoong CWS, Sfeir J, Algeciras-Schimnich A, Clarke BL. A retrospective cohort of tumor-induced osteomalacia and case series of malignant disease. J Clin Endocrinol Metab. 2024 Mar 20 [Epub ahead of print]
    View PubMed
  4. Sada A, Hanson KT, Habermann EB, McKenzie TJ, Lyden ML, Foster TR, Clarke BL, Dy BM. Disparities in Parathyroidectomy: Who Receives Appropriate Treatment for Primary Hyperparathyroidism? J Surg Res. 2023 Nov; 291:151-157 Epub 2023 July 01
    View PubMed
  5. Djulejic V, Petrovic B, Jevtic J, Vujacic M, Clarke BL, Cirovic A, Cirovic A. The role of cadmium in the pathogenesis of myeloid leukemia in individuals with anemia, deficiencies in vitamin D, zinc, and low calcium dietary intake. J Trace Elem Med Biol. 2023 Sep; 79:127263 Epub 2023 July 16
    View PubMed
  6. Watts NB, Bilezikian JP, Bone HG, Clarke BL, Denham D, Levine MA, Mannstadt M, Peacock M, Rothman JG, Vokes TJ, Warren ML, Yin S, Sherry N, Shoback DM. Long-Term Safety and Efficacy of Recombinant Human Parathyroid Hormone (1-84) in Adults With Chronic Hypoparathyroidism. J Endocr Soc. 2023 Mar 6; 7 (5):bvad043 Epub 2023 Apr 04
    View PubMed
  7. Collins MT, Marcucci G, Anders HJ, Beltrami G, Cauley JA, Ebeling PR, Kumar R, Linglart A, Sangiorgi L, Towler DA, Weston R, Whyte MP, Brandi ML, Clarke B, Thakker RV. Author Correction: Skeletal and extraskeletal disorders of biomineralization. Nat Rev Endocrinol. 2023 Jan; 19 (1):62
    View PubMed
  8. Khan AA, Rubin MR, Schwarz P, Vokes T, Shoback DM, Gagnon C, Palermo A, Marcocci C, Clarke BL, Abbott LG, Hofbauer LC, Kohlmeier L, Pihl S, An X, Eng WF, Smith AR, Ukena J, Sibley CT, Shu AD, Rejnmark L. Efficacy and Safety of Parathyroid Hormone Replacement With TransCon PTH in Hypoparathyroidism: 26-Week Results From the Phase 3 PaTHway Trial. J Bone Miner Res. 2023 Jan; 38 (1):14-25 Epub 2022 Nov 12
    View PubMed
  9. Khan AA, Bilezikian JP, Brandi ML, Clarke BL, Gittoes NJ, Pasieka JL, Rejnmark L, Shoback DM, Potts JT, Guyatt GH, Mannstadt M. Evaluation and Management of Hypoparathyroidism Summary Statement and Guidelines from the Second International Workshop. J Bone Miner Res. 2022 Dec; 37 (12):2568-2585 Epub 2022 Nov 14
    View PubMed
  10. Cirovic A, Denic A, Clarke BL, Vassallo R, Cirovic A, Landry GM. A hypoxia-driven occurrence of chronic kidney disease and osteoporosis in COPD individuals: New insights into environmental cadmium exposure. Toxicology. 2022 Dec; 482:153355 Epub 2022 Oct 18
    View PubMed
  11. Yao L, Hui X, Li M, Li J, Ahmed MM, Lin C, Kandi M, Sreekanta A, Makhdami N, Tamilselvan D, Ali DS, Dandurand K, Yang K, Bilezikian JP, Brandi ML, Clarke BL, Mannstadt M, Rejnmark L, Khan AA, Guyatt G. Complications, Symptoms, Presurgical Predictors in Patients With Chronic Hypoparathyroidism: A Systematic Review. J Bone Miner Res. 2022 Dec; 37 (12):2642-2653 Epub 2022 Nov 14
    View PubMed
  12. Clarke BL. Hypoparathyroidism: update of guidelines from the 2022 International Task Force. Arch Endocrinol Metab. 2022 Nov 11; 66 (5):604-610
    View PubMed
  13. Baruth JM, Lapid MI, Clarke B, Shin AY, Atkinson EJ, Eberhard J, Zavatta G, Astrand J. Distal radius fractures and risk of incident neurocognitive disorders in older adults: a retrospective cohort study. Osteoporos Int. 2022 Nov; 33 (11):2307-2314 Epub 2022 July 15
    View PubMed
  14. Yao L, Guyatt G, Ye Z, Bilezikian JP, Brandi ML, Clarke BL, Mannstadt M, Khan AA. Methodology for the Guidelines on Evaluation and Management of Hypoparathyroidism and Primary Hyperparathyroidism. J Bone Miner Res. 2022 Nov; 37 (11):2404-2410 Epub 2022 Oct 17
    View PubMed
  15. Ye Z, Silverberg SJ, Sreekanta A, Tong K, Wang Y, Chang Y, Zhang M, Guyatt G, Tangamornsuksun W, Zhang Y, Manja V, Bakaa L, Couban RJ, Brandi ML, Clarke B, Khan AA, Mannstadt M, Bilezikian JP. The Efficacy and Safety of Medical and Surgical Therapy in Patients With Primary Hyperparathyroidism: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. J Bone Miner Res. 2022 Nov; 37 (11):2351-2372 Epub 2022 Oct 17
    View PubMed
  16. Bilezikian JP, Khan AA, Silverberg SJ, Fuleihan GE, Marcocci C, Minisola S, Perrier N, Sitges-Serra A, Thakker RV, Guyatt G, Mannstadt M, Potts JT, Clarke BL, Brandi ML, International Workshop on Primary Hyperparathyroidism. Evaluation and Management of Primary Hyperparathyroidism: Summary Statement and Guidelines from the Fifth International Workshop. J Bone Miner Res. 2022 Nov; 37 (11):2293-2314 Epub 2022 Oct 17
    View PubMed
  17. Minisola S, Arnold A, Belaya Z, Brandi ML, Clarke BL, Hannan FM, Hofbauer LC, Insogna KL, Lacroix A, Liberman U, Palermo A, Pepe J, Rizzoli R, Wermers R, Thakker RV. Epidemiology, Pathophysiology, and Genetics of Primary Hyperparathyroidism. J Bone Miner Res. 2022 Nov; 37 (11):2315-2329 Epub 2022 Oct 17
    View PubMed
  18. Bjornsdottir S, Clarke BL, Mannstadt M, Langdahl BL. Male osteoporosis-what are the causes, diagnostic challenges, and management. Best Pract Res Clin Rheumatol. 2022 Sep; 36 (3):101766 Epub 2022 Aug 09
    View PubMed
  19. Collins MT, Marcucci G, Anders HJ, Beltrami G, Cauley JA, Ebeling PR, Kumar R, Linglart A, Sangiorgi L, Towler DA, Weston R, Whyte MP, Brandi ML, Clarke B, Thakker RV. Skeletal and extraskeletal disorders of biomineralization. Nat Rev Endocrinol. 2022 Aug; 18 (8):473-489 Epub 2022 May 16
    View PubMed
  20. Khan AA, Rejnmark L, Rubin M, Schwarz P, Vokes T, Clarke B, Ahmed I, Hofbauer L, Marcocci C, Pagotto U, Palermo A, Eriksen E, Brod M, Markova D, Smith A, Pihl S, Mourya S, Karpf DB, Shu AD. PaTH Forward: A Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial of TransCon PTH in Adult Hypoparathyroidism. J Clin Endocrinol Metab. 2022 Jan 1; 107 (1):e372-e385
    View PubMed
  21. Gittoes N, Rejnmark L, Ing SW, Brandi ML, Bjornsdottir S, Hahner S, Hofbauer LC, Houillier P, Khan AA, Levine MA, Mannstadt M, Shoback DM, Vokes TJ, Zhang P, Marelli C, Germak J, Clarke BL. The PARADIGHM (physicians advancing disease knowledge in hypoparathyroidism) registry for patients with chronic hypoparathyroidism: study protocol and interim baseline patient characteristics. BMC Endocr Disord. 2021 Nov 20; 21 (1):232
    View PubMed
  22. Lapid MI, Clarke BL, Ho JB, Ouellette Y, Armbrust TL, Wright RS. Research Involving Participants With Impaired Consent Capacity: An Examination of Methods to Determine Capacity to Consent. Mayo Clin Proc. 2021 Nov; 96 (11):2806-2822
    View PubMed
  23. Bjornsdottir S, Clarke B, Makitie O, Sandstrom A, Tiblad E, Spelman T, Kampe O. Women With Chronic Hypoparathyroidism Have Low Risk of Adverse Pregnancy Outcomes. J Clin Endocrinol Metab. 2021 Oct 21; 106 (11):3312-3319
    View PubMed
  24. Zavatta G, Tebben PJ, McCollough CH, Yu L, Vrieze T, Clarke BL. Basal Ganglia Calcification Is Associated With Local and Systemic Metabolic Mechanisms in Adult Hypoparathyroidism. J Clin Endocrinol Metab. 2021 Jun 16; 106 (7):1900-1917
    View PubMed
  25. Kovacs CS, Chaussain C, Osdoby P, Brandi ML, Clarke B, Thakker RV. The role of biomineralization in disorders of skeletal development and tooth formation. Nat Rev Endocrinol. 2021 Jun; 17 (6):336-349 Epub 2021 May 04
    View PubMed
  26. Zavatta G, Clarke BL. Glucocorticoid- and Transplantation-Induced Osteoporosis. Endocrinol Metab Clin North Am. 2021 Jun; 50 (2):251-273
    View PubMed
  27. Zavatta G, Clarke BL. Normocalcemic Primary Hyperparathyroidism: Need for a Standardized Clinical Approach. Endocrinol Metab (Seoul). 2021 Jun; 36 (3):525-535 Epub 2021 June 01
    View PubMed
  28. Arnold A, Dennison E, Kovacs CS, Mannstadt M, Rizzoli R, Brandi ML, Clarke B, Thakker RV. Hormonal regulation of biomineralization. Nat Rev Endocrinol. 2021 May; 17 (5):261-275 Epub 2021 Mar 16
    View PubMed
  29. Zavatta G, Clarke BL. Basal ganglia calcification in hypoparathyroidism and pseudohypoparathyroidism: local and systemic metabolic mechanisms. J Endocrinol Invest. 2021 Feb; 44 (2):245-253 Epub 2020 July 13
    View PubMed
  30. Lapid MI, Meagher KM, Giunta HC, Clarke BL, Ouellette Y, Armbrust TL, Sharp RR, Wright RS. Ethical Challenges in COVID-19 Biospecimen Research: Perspectives From Institutional Review Board Members and Bioethicists. Mayo Clin Proc. 2021 Jan; 96 (1):165-173 Epub 2020 Oct 23
    View PubMed
  31. Zavatta G, Clarke BL. Challenges in the management of chronic hypoparathyroidism. Endocr Connect. 2020 Sep 1; 9 (10):R229-40 Epub 2020 Sept 01
    View PubMed
  32. Zavatta G, Clarke BL. Normocalcemic Hyperparathyroidism: A Heterogeneous Disorder Often Misdiagnosed? JBMR Plus. 2020 Aug; 4 (8):e10391 Epub 2020 July 24
    View PubMed
  33. Yu EW, Tsourdi E, Clarke BL, Bauer DC, Drake MT. Osteoporosis Management in the Era of COVID-19. J Bone Miner Res 2020 Jun; 35 (6):1009-1013 Epub 2020 May 26
    View PubMed
  34. Keaveny TM, Clarke BL, Cosman F, Orwoll ES, Siris ES, Khosla S, Bouxsein ML. Biomechanical Computed Tomography analysis (BCT) for clinical assessment of osteoporosis. Osteoporos Int. 2020 Jun; 31 (6):1025-1048 Epub 2020 Apr 26
    View PubMed
  35. Conley RB, Adib G, Adler RA, Akesson KE, Alexander IM, Amenta KC, Blank RD, Brox WT, Carmody EE, Chapman-Novakofski K, Clarke BL, Cody KM, Cooper C, Crandall CJ, Dirschl DR, Eagen TJ, Elderkin AL, Fujita M, Greenspan SL, Halbout P, Hochberg MC, Javaid M, Jeray KJ, Kearns AE, King T, Koinis TF, Koontz JS, Kuzma M, Lindsey C, Lorentzon M, Lyritis GP, Michaud LB, Miciano A, Morin SN, Mujahid N, Napoli N, Olenginski TP, Puzas JE, Rizou S, Rosen CJ, Saag K, Thompson E, Tosi LL, Tracer H, Khosla S, Kiel DP. Secondary Fracture Prevention: Consensus Clinical Recommendations From a Multistakeholder Coalition. Orthop Nurs. 2020 May/Jun; 39 (3):145-161
    View PubMed
  36. Conley RB, Adib G, Adler RA, Akesson KE, Alexander IM, Amenta KC, Blank RD, Brox WT, Carmody EE, Chapman-Novakofski K, Clarke BL, Cody KM, Cooper C, Crandall CJ, Dirschl DR, Eagen TJ, Elderkin AL, Fujita M, Greenspan SL, Halbout P, Hochberg MC, Javaid M, Jeray KJ, Kearns AE, King T, Koinis TF, Koontz JS, Kuzma M, Lindsey C, Lorentzon M, Lyritis GP, Michaud LB, Miciano A, Morin SN, Mujahid N, Napoli N, Olenginski TP, Puzas JE, Rizou S, Rosen CJ, Saag K, Thompson E, Tosi LL, Tracer H, Khosla S, Kiel DP. Secondary Fracture Prevention: Consensus Clinical Recommendations from a Multistakeholder Coalition. J Orthop Trauma. 2020 Apr; 34 (4):e125-e141
    View PubMed
  37. Iniguez-Ariza NM, Bible KC, Clarke BL. Bone metastases in thyroid cancer. J Bone Oncol. 2020 Apr; 21:100282 Epub 2020 Feb 19
    View PubMed
  38. Siggelkow H, Clarke BL, Germak J, Marelli C, Chen K, Dahl-Hansen H, Glenister E, Bent-Ennakhil N, Judge D, Mycock K, Bollerslev J. Burden of illness in not adequately controlled chronic hypoparathyroidism: Findings from a 13-country patient and caregiver survey. Clin Endocrinol (Oxf). 2020 Feb; 92 (2):159-168 Epub 2019 Dec 11
    View PubMed
  39. Weivoda MM, Chew CK, Monroe DG, Farr JN, Atkinson EJ, Geske JR, Eckhardt B, Thicke B, Ruan M, Tweed AJ, McCready LK, Rizza RA, Matveyenko A, Kassem M, Andersen TL, Vella A, Drake MT, Clarke BL, Oursler MJ, Khosla S. Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism. Nat Commun. 2020 Jan 7; 11 (1):87 Epub 2020 Jan 07
    View PubMed
  40. Conley RB, Adib G, Adler RA, Akesson KE, Alexander IM, Amenta KC, Blank RD, Brox WT, Carmody EE, Chapman-Novakofski K, Clarke BL, Cody KM, Cooper C, Crandall CJ, Dirschl DR, Eagen TJ, Elderkin AL, Fujita M, Greenspan SL, Halbout P, Hochberg MC, Javaid M, Jeray KJ, Kearns AE, King T, Koinis TF, Koontz JS, Kuzma M, Lindsey C, Lorentzon M, Lyritis GP, Michaud LB, Miciano A, Morin SN, Mujahid N, Napoli N, Olenginski TP, Puzas JE, Rizou S, Rosen CJ, Saag K, Thompson E, Tosi LL, Tracer H, Khosla S, Kiel DP. Secondary Fracture Prevention: Consensus Clinical Recommendations from a Multistakeholder Coalition. J Bone Miner Res. 2020 Jan; 35 (1):36-52 Epub 2019 Dec 01
    View PubMed
  41. Mannstadt M, Clarke BL, Bilezikian JP, Bone H, Denham D, Levine MA, Peacock M, Rothman J, Shoback DM, Warren ML, Watts NB, Lee HM, Sherry N, Vokes TJ. Safety and Efficacy of 5 Years of Treatment With Recombinant Human Parathyroid Hormone in Adults With Hypoparathyroidism. J Clin Endocrinol Metab. 2019 Nov 1; 104 (11):5136-5147
    View PubMed
  42. Leder BZ, Clarke BL, Shane E, Khosla S, Kiel DP. A Lot of Progress, With More to Be Done: A Response to NIH Pathways to Prevention Report "Research Gaps for Long-Term Drug Therapies for Osteoporotic Fracture Prevention". J Bone Miner Res. 2019 Sep; 34 (9):1549-1551 Epub 2019 July 25
    View PubMed
  43. Davidge-Pitts C, Clarke BL. Transgender bone health. Maturitas. 2019 Sep; 127:35-42 Epub 2019 May 14
    View PubMed
  44. Lapid MI, Clarke BL, Wright RS. Institutional Review Boards: What Clinician Researchers Need to Know. Mayo Clin Proc. 2019 Mar; 94 (3):515-525
    View PubMed
  45. Khan AA, Koch CA, Van Uum S, Baillargeon JP, Bollerslev J, Brandi ML, Marcocci C, Rejnmark L, Rizzoli R, Shrayyef MZ, Thakker R, Yildiz BO, Clarke B. Standards of care for hypoparathyroidism in adults: a Canadian and International Consensus. Eur J Endocrinol. 2019 Mar; 180 (3):P1-P22
    View PubMed
  46. Khan AA, Clarke B, Rejnmark L, Brandi ML. MANAGEMENT OF ENDOCRINE DISEASE: Hypoparathyroidism in pregnancy: review and evidence-based recommendations for management. Eur J Endocrinol. 2019 Feb 1; 180 (2):R37-R44
    View PubMed
  47. Clarke BL. Asymptomatic Primary Hyperparathyroidism. Front Horm Res. 2019; 51:13-22 Epub 2018 Nov 19
    View PubMed
  48. Clarke BL. Epidemiology and Complications of Hypoparathyroidism. Endocrinol Metab Clin North Am. 2018 Dec; 47 (4):771-782 Epub 2018 Oct 11
    View PubMed
  49. Chew CK, Clarke BL. Causes of low peak bone mass in women. Maturitas. 2018 May; 111:61-68 Epub 2017 Dec 15
    View PubMed
  50. Vokes TJ, Mannstadt M, Levine MA, Clarke BL, Lakatos P, Chen K, Piccolo R, Krasner A, Shoback DM, Bilezikian JP. Recombinant Human Parathyroid Hormone Effect on Health-Related Quality of Life in Adults With Chronic Hypoparathyroidism. J Clin Endocrinol Metab. 2018 Feb 1; 103 (2):722-731
    View PubMed
  51. Sakka S, Gafni RI, Davies JH, Clarke B, Tebben P, Samuels M, Saraff V, Klaushofer K, Fratzl-Zelman N, Roschger P, Rauch F, Hogler W. Bone Structural Characteristics and Response to Bisphosphonate Treatment in Children With Hajdu-Cheney Syndrome. J Clin Endocrinol Metab. 2017 Nov 1; 102 (11):4163-4172
    View PubMed
  52. Bilezikian JP, Clarke BL, Mannstadt M, Rothman J, Vokes T, Lee HM, Krasner A. Safety and Efficacy of Recombinant Human Parathyroid Hormone in Adults With Hypoparathyroidism Randomly Assigned to Receive Fixed 25-mug or 50-mug Daily Doses. Clin Ther. 2017 Oct; 39 (10):2096-2102 Epub 2017 Sept 21
    View PubMed
  53. Chew CK, Clarke BL. Biochemical Testing Relevant to Bone. Endocrinol Metab Clin North Am. 2017 Sep; 46 (3):649-667 Epub 2017 June 20
    View PubMed
  54. Mannstadt M, Bilezikian JP, Thakker RV, Hannan FM, Clarke BL, Rejnmark L, Mitchell DM, Vokes TJ, Winer KK, Shoback DM. Hypoparathyroidism. Nat Rev Dis Primers. 2017 Aug 31; 3:17055
    View PubMed
  55. Lapid MI, Kung S, Frye MA, Biernacka JM, Geske JR, Drake MT, Jankowski MD, Clarke BL. Association of the serotonin transporter-linked polymorphic region genotype with lower bone mineral density. Transl Psychiatry. 2017 Aug 22; 7 (8):e1213
    View PubMed
  56. Kotwal A, Clarke BL. Melorheostosis: a Rare Sclerosing Bone Dysplasia. Curr Osteoporos Rep. 2017 Aug; 15 (4):335-342
    View PubMed
  57. Drake MT, Clarke BL, Oursler MJ, Khosla S. Cathepsin K Inhibitors for Osteoporosis: Biology, Potential Clinical Utility, and Lessons Learned. Endocr Rev. 2017 Aug 1; 38 (4):325-350
    View PubMed
  58. Lee B, Iwaniec UT, Turner RT, Lin YW, Clarke BL, Gingery A, Wei LN. RIP140 in monocytes/macrophages regulates osteoclast differentiation and bone homeostasis. JCI Insight. 2017 Apr 06; 2(7):e90517.
    View PubMed
  59. Lewiecki EM, Bilezikian JP, Bukata SV, Camacho P, Clarke BL, McClung MR, Miller PD, Shepherd J. Proceedings of the 2016 Santa Fe Bone Symposium: New Concepts in the Management of Osteoporosis and Metabolic Bone Diseases. J Clin Densitom. 2017 Apr - Jun; 20 (2):134-152 Epub 2017 Feb 06
    View PubMed
  60. Chew CK, Clarke BL. Abaloparatide: Recombinant human PTHrP (1-34) anabolic therapy for osteoporosis. Maturitas. 2017 Mar; 97:53-60 Epub 2016 Dec 15
    View PubMed
  61. Donegan D, Singh Ospina N, Rodriguez-Gutierrez R, Al-Hilli Z, Thompson GB, Clarke BL, Young WF Jr. Long-term outcomes in patients with multiple endocrine neoplasia type 1 and pancreaticoduodenal neuroendocrine tumours. Clin Endocrinol (Oxf). 2017 Feb; 86 (2):199-206 Epub 2016 Nov 17
    View PubMed
  62. Khan AA, Hanley DA, Rizzoli R, Bollerslev J, Young JE, Rejnmark L, Thakker R, D'Amour P, Paul T, Van Uum S, Shrayyef MZ, Goltzman D, Kaiser S, Cusano NE, Bouillon R, Mosekilde L, Kung AW, Rao SD, Bhadada SK, Clarke BL, Liu J, Duh Q, Lewiecki EM, Bandeira F, Eastell R, Marcocci C, Silverberg SJ, Udelsman R, Davison KS, Potts JT Jr, Brandi ML, Bilezikian JP. Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus. Osteoporos Int. 2017 Jan; 28 (1):1-19 Epub 2016 Sept 09
    View PubMed
  63. Clarke BL, Vokes TJ, Bilezikian JP, Shoback DM, Lagast H, Mannstadt M. Effects of parathyroid hormone rhPTH(1-84) on phosphate homeostasis and vitamin D metabolism in hypoparathyroidism: REPLACE phase 3 study. Endocrine. 2017 Jan; 55 (1):273-282 Epub 2016 Oct 12
    View PubMed
  64. Camacho PM, Petak SM, Binkley N, Clarke BL, Harris ST, Hurley DL, Kleerekoper M, Lewiecki EM, Miller PD, Narula HS, Pessah-Pollack R, Tangpricha V, Wimalawansa SJ, Watts NB. American Association of Clinical Endocrinologists and American College of Endocrinology Clinical practice guidelines for the diagnosis and treatment of postmenopausal osteoporosis-2016 Endocrine Practice. 2016 Sep; 22:1-42.
  65. Camacho PM, Petak SM, Binkley N, Clarke BL, Harris ST, Hurley DL, Kleerekoper M, Lewiecki EM, Miller PD, Narula HS, Pessah-Pollack R, Tangpricha V, Wimalawansa SJ, Watts NB. American association of clinical endocrinologists and american college of endocrinology clinical practice guidelines for the diagnosis and treatment of postmenopausal osteoporosis-2016 executive summary Endocrine Practice. 2016 Sep; 22: (9)1111-8.
  66. Brandi ML, Bilezikian JP, Shoback D, Bouillon R, Clarke BL, Thakker RV, Khan AA, Potts JT Jr. Management of Hypoparathyroidism: Summary Statement and Guidelines. J Clin Endocrinol Metab. 2016 Jun; 101 (6):2273-83 Epub 2016 Mar 04
    View PubMed
  67. Clarke BL, Brown EM, Collins MT, Juppner H, Lakatos P, Levine MA, Mannstadt MM, Bilezikian JP, Romanischen AF, Thakker RV. Epidemiology and Diagnosis of Hypoparathyroidism. J Clin Endocrinol Metab. 2016 Jun; 101 (6):2284-99 Epub 2016 Mar 04
    View PubMed
  68. Singh Ospina N, Sebo TJ, Thompson GB, Clarke BL, Young WF Jr. Prevalence of parathyroid carcinoma in 348 patients with multiple endocrine neoplasia type 1 - case report and review of the literature. Clin Endocrinol (Oxf). 2016 Feb; 84 (2):244-249 Epub 2015 Feb 12
    View PubMed
  69. Adler RA, El-Hajj Fuleihan G, Bauer DC, Camacho PM, Clarke BL, Clines GA, Compston JE, Drake MT, Edwards BJ, Favus MJ, Greenspan SL, McKinney R Jr, Pignolo RJ, Sellmeyer DE. Managing Osteoporosis in Patients on Long-Term Bisphosphonate Treatment: Report of a Task Force of the American Society for Bone and Mineral Research. J Bone Miner Res. 2016 Jan; 31 (1):16-35
    View PubMed
  70. Abate EG, Clarke BL. Review of Hypoparathyroidism. Front Endocrinol (Lausanne). 2016; 7:172 Epub 2017 Jan 16
    View PubMed
  71. Fidler JL, Murthy NS, Khosla S, Clarke BL, Bruining DH, Kopperdahl DL, Lee DC, Keaveny TM. Comprehensive Assessment of Osteoporosis and Bone Fragility with CT Colonography. Radiology. 2016 Jan; 278 (1):172-80 Epub 2015 July 22
    View PubMed
  72. Iniguez-Ariza NM, Clarke BL. Bone biology, signaling pathways, and therapeutic targets for osteoporosis. Maturitas. 2015 Oct; 82 (2):245-55 Epub 2015 July 17
    View PubMed
  73. Shah M, Bancos I, Thompson GB, Richards ML, Kasperbauer JL, Clarke BL, Drake MT, Stan MN. Teriparatide Therapy and Reduced Postoperative Hospitalization for Postsurgical Hypoparathyroidism. JAMA Otolaryngol Head Neck Surg. 2015 Sep; 141: (9)822-7.
    View PubMed
  74. Drake MT, Clarke BL, Lewiecki EM. The Pathophysiology and Treatment of Osteoporosis. Clin Ther. 2015 Aug; 37 (8):1837-50 Epub 2015 July 07
    View PubMed
  75. Fuleihan Gel-H, Bouillon R, Clarke B, Chakhtoura M, Cooper C, McClung M, Singh RJ. Serum 25-Hydroxyvitamin D Levels: Variability, Knowledge Gaps, and the Concept of a Desirable Range. J Bone Miner Res. 2015 Jul; 30 (7):1119-33 Epub 2015 May 07
    View PubMed
  76. Silverberg SJ, Clarke BL, Peacock M, Bandeira F, Boutroy S, Cusano NE, Dempster D, Lewiecki EM, Liu JM, Minisola S, Rejnmark L, Silva BC, Walker MD, Bilezikian JP. Current issues in the presentation of asymptomatic primary hyperparathyroidism: proceedings of the Fourth International Workshop. J Clin Endocrinol Metab 2014 Oct; 99 (10):3580-94 Epub 2014 Aug 27
    View PubMed
  77. PTH in post-surgical hypoparathyroidism 84th Annual Meeting of the American Thyroid Association Program. 2014.
  78. Sheikh-Ali M, Keaveny AP, Chamseddin A, Aguirre L, Clarke B, Meek S. 25-Hydroxyvitamin D levels and acute cellular rejection in liver transplant patients. Endocr Pract. 2014 Aug; 20 (8):769-74
    View PubMed
  79. Hadker N, Egan J, Sanders J, Lagast H, Clarke BL. Understanding the burden of illness associated with hypoparathyroidism reported among patients in the PARADOX study. Endocr Pract. 2014 Jul; 20 (7):671-9
    View PubMed
  80. Clarke BL. Bone disease in hypoparathyroidism. Arq Bras Endocrinol Metabol. 2014 Jul; 58 (5):545-52
    View PubMed
  81. Kling JM, Clarke BL, Sandhu NP. Osteoporosis prevention, screening, and treatment: a review. J Womens Health (Larchmt). 2014 Jul; 23 (7):563-72 Epub 2014 Apr 25
    View PubMed
  82. Clarke BL. Anti-sclerostin antibodies: utility in treatment of osteoporosis. Maturitas. 2014 Jul; 78 (3):199-204 Epub 2014 May 02
    View PubMed
  83. Zangeneh F, Clarke BL, Hurley DL, Watts NB, Miller PD. Chronic Kidney Disease-Mineral and Bone Disorders (CKD-MBDs): What the Endocrinologist Needs to Know. Endocr Pract. 2014 May; 20 (5):500-16
    View PubMed
  84. Clarke BL, Kay Berg J, Fox J, Cyran JA, Lagast H. Pharmacokinetics and pharmacodynamics of subcutaneous recombinant parathyroid hormone (1-84) in patients with hypoparathyroidism: an open-label, single-dose, phase I study. Clin Ther. 2014 May; 36(5):722-36. Epub 2014 May 05.
    View PubMed
  85. Weber NK, Fidler JL, Keaveny TM, Clarke BL, Khosla S, Fletcher JG, Lee DC, Pardi DS, Loftus EV Jr, Kane SV, Barlow JM, Murthy NS, Becker BD, Bruining DH. Validation of a CT-derived method for osteoporosis screening in IBD patients undergoing contrast-enhanced CT enterography. Am J Gastroenterol. 2014 Mar; 109 (3):401-8 Epub 2014 Jan 21
    View PubMed
  86. Mannstadt M, Clarke BL, Vokes T, Brandi ML, Ranganath L, Fraser WD, Lakatos P, Bajnok L, Garceau R, Mosekilde L, Lagast H, Shoback D, Bilezikian JP. Efficacy and safety of recombinant human parathyroid hormone (1-84) in hypoparathyroidism (REPLACE): a double-blind, placebo-controlled, randomised, phase 3 study. Lancet Diabetes Endocrinol. 2013 Dec; 1 (4):275-83 Epub 2013 Oct 07
    View PubMed
  87. Lim V, Clarke BL. Coexisting primary hyperparathyroidism and sarcoidosis cause increased angiotensin-converting enzyme and decreased parathyroid hormone and phosphate levels. J Clin Endocrinol Metab. 2013 May; 98 (5):1939-45 Epub 2013 Mar 14
    View PubMed
  88. Turcu AF, Clarke BL. Fibrous dysplasia of bone associated with primary hyperparathyroidism. Endocr Pract. 2013 Mar-Apr; 19 (2):226-30
    View PubMed
  89. Clarke BL, Drake MT. Clinical utility of serum sclerostin measurements. Bonekey Rep. 2013; 2:361 Epub 2013 June 05
    View PubMed
  90. Clarke BL. Epidemiology of primary hyperparathyroidism. J Clin Densitom. 2013 Jan-Mar; 16 (1):8-13
    View PubMed
  91. Lim V, Clarke BL. New therapeutic targets for osteoporosis: beyond denosumab. Maturitas. 2012 Nov; 73(3):269-72. Epub 2012 Aug 24.
    View PubMed
  92. Ng AC, Drake MT, Clarke BL, Sems SA, Atkinson EJ, Achenbach SJ, Melton LJ 3rd. Trends in subtrochanteric, diaphyseal, and distal femur fractures, 1984-2007. Osteoporos Int. 2012 Jun; 23 (6):1721-6 Epub 2011 Sept 10
    View PubMed
  93. Clarke BL. Corticosteroid-induced osteoporosis: an update for dermatologists. Am J Clin Dermatol. 2012 Jun 1; 13: (3)167-90.
    View PubMed
  94. Clarke BL. Epidemiology of primary hyperparathyroidism. J Clin Densitom. 2012.
  95. Turcu A, Clarke BL. Association of primary hyperparathyroidism with fibrous dysplasia: a case series and review of the literature. Endocrine Pract. 2012.
  96. Bilezikian JP, Khan A, Potts JT Jr, Brandi ML, Clarke BL, Shoback D, Juppner H, D'Amour P, Fox J, Rejnmark L, Mosekilde L, Rubin MR, Dempster D, Gafni R, Collins MT, Sliney J, Sanders J. Hypoparathyroidism in the adult: epidemiology, diagnosis, pathophysiology, target-organ involvement, treatment, and challenges for future research. J Bone Miner Res. 2011 Oct; 26(10):2317-37.
    View PubMed
  97. Thacher TD, Clarke BL. Vitamin D insufficiency. Mayo Clin Proc. 2011 Jan; 86 (1):50-60
    View PubMed
  98. Clarke BL, Khosla S. Female reproductive system and bone. Arch Biochem Biophys. 2010 Nov 1; 503 (1):118-28 Epub 2010 July 14
    View PubMed
  99. Clarke BL, Khosla S. Physiology of bone loss. Radiol Clin North Am. 2010 May; 48 (3):483-95
    View PubMed
  100. Kirmani S, Tebben PJ, Lteif AN, Gordon D, Clarke BL, Hefferan TE, Yaszemski MJ, McGrann PS, Lindor NM, Ellison JW. Germline TGF-beta receptor mutations and skeletal fragility: a report on two patients with Loeys-Dietz syndrome. Am J Med Genet A. 2010 Apr; 152A (4):1016-9
    View PubMed
  101. Chandran M, Chng CL, Zhao Y, Bee YM, Phua LY, Clarke BL. Novel PHEX gene mutation associated with X linked hypophosphatemic rickets. Nephron Physiol. 2010; 116(3):p17-21. Epub 2010 Jul 28.
    View PubMed
  102. Clarke BL, Khosla S. Modulators of androgen and estrogen receptor activity. Crit Rev Eukaryot Gene Expr. 2010; 20 (4):275-94
    View PubMed
  103. Clarke BL. New and emerging treatments for osteoporosis. Clin Endocrinol (Oxf). 2009 Sep; 71: (3)309-21.
    View PubMed
  104. Clarke BL, Khosla S. Assessing the true impact of recurrent fractures on fracture risk. J Bone Miner Res. 2009 Sep; 24 (9):1512-4
    View PubMed
  105. Clarke BL, Khosla S. New selective estrogen and androgen receptor modulators. Curr Opin Rheumatol. 2009 Jul; 21 (4):374-9
    View PubMed
  106. Clarke BL, Khosla S. Androgens and bone. Steroids. 2009 Mar; 74 (3):296-305 Epub 2008 Oct 17
    View PubMed
  107. Kallmes DF, Rad AE, Gray LA, McDonald RJ, Clarke BL. Bisphosphonates are not associated with vertebral osteonecrosis. J Bone Miner Metab. 2009; 27 (4):452-5 Epub 2009 Mar 27
    View PubMed
  108. Khan YK, Kalaaji AN, Clarke BL. Glucocorticoid-induced osteoporosis in dermatologic practice: a review. J Drugs Dermatol. 2008 Nov; 7(11):1053-9.
    View PubMed
  109. Clarke B. Normal bone anatomy and physiology. Clin J Am Soc Nephrol. 2008 Nov; 3 Suppl 3 (Suppl 3):S131-9
    View PubMed
  110. Drake MT, Clarke BL, Khosla S. Bisphosphonates: mechanism of action and role in clinical practice. Mayo Clin Proc. 2008 Sep; 83 (9):1032-45
    View PubMed
  111. Koka S, Clarke BL, Amin S, Gertz M, Ruggiero SL. Oral bisphosphonate therapy and osteonecrosis of the jaw: what to tell the concerned patient. Int J Prosthodont. 2007 Mar-Apr; 20 (2):115-22
    View PubMed
  112. Clarke BL, Amin S, Commentary on Yang YX, Lewis JD, Epstein S, Metz DC. Long-term proton pump inhibitor therapy and risk of hip fracture. Nature Clin Pract Endocrinol Metab. 2007; 296:2947-2953.
  113. Mauck KF, Clarke BL. Diagnosis, screening, prevention, and treatment of osteoporosis. Mayo Clin Proc. 2006 May; 81 (5):662-72
    View PubMed
  114. Hodgson SF, Clarke BL, Tebben PJ, Mullan BP, Cooney WP 3rd, Shives TC. Oncogenic osteomalacia: localization of underlying peripheral mesenchymal tumors with use of Tc 99m sestamibi scintigraphy. Endocr Pract. 2006 Jan-Feb; 12 (1):35-42
    View PubMed
  115. Zein CO, Jorgensen RA, Clarke B, Wenger DE, Keach JC, Angulo P, Lindor KD. Alendronate improves bone mineral density in primary biliary cirrhosis: a randomized placebo-controlled trial. Hepatology. 2005 Oct; 42 (4):762-71
    View PubMed
  116. Tebben PJ, Singh RJ, Clarke BL, Kumar R. Fibroblast growth factor 23, parathyroid hormone, and 1alpha,25-dihydroxyvitamin D in surgically treated primary hyperparathyroidism. Mayo Clin Proc. 2004 Dec; 79 (12):1508-13
    View PubMed
  117. Guichelaar MM, Malinchoc M, Sibonga J, Clarke BL, Hay JE. Immunosuppressive and postoperative effects of orthotopic liver transplantation on bone metabolism. Liver Transpl. 2004 May; 10(5):638-47.
    View PubMed
  118. Sinaki M, Canvin JC, Phillips BE, Clarke BL. Site specificity of regular health club exercise on muscle strength, fitness, and bone density in women aged 29 to 45 years. Mayo Clin Proc. 2004 May; 79 (5):639-44
    View PubMed
  119. Vautour LM, Melton LJ 3rd, Clarke BL, Achenbach SJ, Oberg AL, McCarthy JT. Long-term fracture risk following renal transplantation: a population-based study. Osteoporos Int. 2004 Feb; 15 (2):160-7 Epub 2003 Dec 09
    View PubMed
  120. Guichelaar MMJ, Malinchoc M, Sibonga JD, Clarke BL, Hay JE. Bone histomorphometric changes after liver transplantation for chronic cholestatic liver disease. J Bone Miner Res. 2003 Dec; 18(12):2190-9.
    View PubMed
  121. Guichelaar MM, Malinchoc M, Sibonga J, Clarke BL, Hay JE. Bone metabolism in advanced cholestatic liver disease: analysis by bone histomorphometry. Hepatology. 2002 Oct; 36(4 Pt 1):895-903.
    View PubMed
  122. Clarke BL. Diagnosis and management of postmenopausal osteoporosis: case study and commentary. Journal of Clinical Outcomes Management. 2002 Jul; 9(7):397-408.
  123. Clarke BL, Ebeling PR, Jones JD, Wahner HW, O'Fallon WM, Riggs BL, Fitzpatrick LA. Predictors of bone mineral density in aging healthy men varies by skeletal site. Calcif Tissue Int. 2002 Mar; 70: (3)137-45.
    View PubMed
  124. Velan GJ, Currier BL, Clarke BL, Yaszemski MJ. Ossification of the posterior longitudinal ligament in vitamin D-resistant rickets: case report and review of the literature. Spine (Phila Pa 1976). 2001 Mar 1; 26 (5):590-3
    View PubMed
  125. Garovic VD, Clarke BL, Chilson TS, Specks U. Diabetes insipidus and anterior pituitary insufficiency as presenting features of Wegener's granulomatosis. Am J Kidney Dis. 2001 Jan; 37 (1):E5
    View PubMed
  126. Clarke BL, Khosla S. Postmenopausal osteoporosis. Hosp Phys Endocrinol Board Rev Man. 2000; 2:1-12.
  127. Clarke BL, Ebeling PR, Jones JD, Wahner HW, O'Fallon WM, Riggs BL, Fitzpatrick LA. Changes in quantitative bone histomorphometry in aging healthy men. J Clin Endocrinol Metab. 1996 Jun; 81(6):2264-70.
    View PubMed
  128. Clarke BL, Wynne AG, Wilson DM, Fitzpatrick LA. Osteomalacia associated with adult Fanconi's syndrome: clinical and diagnostic features. Clin Endocrinol (Oxf). 1995 Oct; 43 (4):479-90
    View PubMed
  129. Clarke BL, Beyer HS, Weisman I, Sharp B, Nippoldt TB. Rapid recovery from adrenal insufficiency due to bilateral adrenal hemorrhage. Endocrinologist. 1995 Jul; 5:312-315.
  130. Clarke BL, Muhs JM, O'Connell MJ, McCarthy JT, O'Fallon WM, Riggs BL. Assessment of bone resorption in metabolic bone disorders using a new enzyme immunoassay for urinary free pyridinoline: comparison with standard methods of assessment of bone formation. Endocr Pract. 1995 Jul-Aug; 1(4):248-56.
  131. Ingram RT, Park YK, Clarke BL, Fitzpatrick LA. Age- and gender-related changes in the distribution of osteocalcin in the extracellular matrix of normal male and female bone. Possible involvement of osteocalcin in bone remodeling. J Clin Invest. 1994 Mar; 93 (3):989-97
    View PubMed
  132. Ingram RT, Clarke BL, Fisher LW, Fitzpatrick LA. Distribution of noncollagenous proteins in the matrix of adult human bone: evidence of anatomic and functional heterogeneity. J Bone Miner Res. 1993 Sep; 8(9):1019-29.
    View PubMed
  133. Clarke BL, Hassager C, Fitzpatrick LA. Regulation of parathyroid hormone release by protein kinase-C is dependent on extracellular calcium in bovine parathyroid cells. Endocrinology. 1993 Mar; 132 (3):1168-75
    View PubMed
  134. Klandorf H, Clarke BL, Scheck AC, Brown J. Regulation of glucokinase activity in the domestic fowl. Biochem Biophys Res Commun. 1986 Sep 30; 139(3):1086-93.
    View PubMed
  135. Klandorf H, Clarke BL, Brown J. Altered glucagon release in biotin deficiency. Gen Comp Endocrinol. 1986; 65:133-140.