打印 概述选择性免疫球蛋白 A 缺陷是一种免疫系统疾病,患病者缺乏或没有足够的免疫球蛋白 A(IgA)— 一种抗感染的蛋白质(抗体)。大多数选择性免疫球蛋白 A 缺陷患者不会出现反复感染。然而,一些 IgA 缺陷患者会出现感染性肺炎、耳部感染、鼻窦感染、过敏、哮喘和腹泻。 自身免疫性疾病会导致您的免疫系统攻击自身体内的特定器官或组织,其可能伴有选择性免疫球蛋白 A 缺陷。伴有 IgA 缺陷的常见自身免疫性疾病包括类风湿关节炎、狼疮、乳糜泻或炎性肠病。产品与服务书籍:《妙佑医疗国际家庭健康手册》第 5 版简报:妙佑医疗国际卫生来信 — 数字版显示妙佑医疗国际的更多产品 症状Most people with selective IgA deficiency have no symptoms. Some people have illnesses more often than is typical. They also may have a particular illness that returns often. Having frequent illnesses doesn't necessarily mean a person has selective IgA deficiency. People with selective IgA deficiency may have frequent or repeat episodes of the following: Ear infections, particularly in young children. Colds. Sinus infections. Lung illnesses, such as bronchitis or pneumonia. Giardiasis, a parasitic illness of the digestive system that causes diarrhea. Children with frequent illnesses may not eat well or may not gain weight typical for their age. 申请预约 病因Selective IgA deficiency happens when immune system cells don't produce any or produce very few IgA antibodies. The exact reason cells don't produce these antibodies isn't known. Certain medicines used to treat seizures, epilepsy or rheumatoid arthritis may cause selective IgA deficiency in some people. The deficiency may continue after the medicine is no longer taken. 风险因素A family history of selective IgA deficiency increases the risk of the condition. Certain variations of genes appear to be linked to selective IgA deficiency, but no gene is known to directly cause the condition. 并发症People with selective IgA deficiency are at increased risk of other long-term conditions. These include: Allergies and asthma. Rheumatoid arthritis. Celiac disease. Inflammatory bowel disease. Common variable immunodeficiency, which is a lack of two or more types of immunoglobulins. Risk of reaction to blood productsPeople with selective IgA deficiency are at risk of reactions to blood transfusions or blood products. Because a person's body doesn't make IgA, the immune system may see it as a foreign substance in a blood transfusion or other treatment with blood products. A reaction may cause high fever, chills, sweating and other symptoms. Rarely, people with selective IgA deficiency have a life-threatening allergic reaction, called anaphylaxis (an-uh-fuh-LAK-sis). Healthcare professionals recommend wearing a medical bracelet. A bracelet can show that you have selective IgA deficiency and should receive modified blood or blood products. 来自妙佑医疗国际员工 在 Mayo Clinic 治疗 申请预约 诊断与治疗 March 05, 2022 打印 Living with 选择性免疫球蛋白 a 缺乏症? Connect with others like you for support and answers to your questions in the Blood Cancers & Disorders support group on Mayo Clinic Connect, a patient community. Blood Cancers & Disorders Discussions My Bone Marrow Transplant (BMT/SCT) story: Will you share yours? 423 Replies Sun, Jul 21, 2024 chevron-right CLL leukemia: Just diagnosed, what can be done? 200 Replies Sat, Jul 20, 2024 chevron-right T cell large granulocytic leukemia 12 Replies Thu, Jul 18, 2024 chevron-right See more discussions 显示参考文献 Selective IgA deficiency. Merck Manual Professional Version. https://www.merckmanuals.com/professional/immunology-allergic-disorders/immunodeficiency-disorders/selective-iga-deficiency. Accessed Feb. 14, 2020. Selective IgA deficiency. Immune Deficiency Foundation. https://primaryimmune.org/about-primary-immunodeficiencies/specific-disease-types/selective-iga-deficiency. Accessed Feb. 14, 2020. Brown AY. Allscripts EPSi. Mayo Clinic. Nov. 14, 2019. 相关 产品与服务 书籍:《妙佑医疗国际家庭健康手册》第 5 版 简报:妙佑医疗国际卫生来信 — 数字版 显示更多来自妙佑医疗国际的产品和服务 选择性免疫球蛋白 A 缺乏症症状与病因诊断与治疗医生与科室在 Mayo Clinic 治疗 Advertisement 妙佑医疗国际不为任何公司或产品背书。广告收入为我们的非营利使命提供支持。 广告与赞助政策 政策 机会 广告选择 妙佑医疗国际出版社 浏览妙佑医疗国际出版社提供的畅销书以及书籍和简报的特别优惠。 《妙佑医疗国际论失禁》(Mayo Clinic on Incontinence) - 妙佑医疗国际出版社《妙佑医疗国际论失禁》(Mayo Clinic on Incontinence)《糖尿病基本知识》 - 妙佑医疗国际出版社《糖尿病基本知识》妙佑医疗国际论平衡和听觉 - 妙佑医疗国际出版社妙佑医疗国际论平衡和听觉妙佑医疗国际免费饮食方案评估 - 妙佑医疗国际出版社妙佑医疗国际免费饮食方案评估妙佑医疗国际健康通讯 — 免费书籍 - 妙佑医疗国际出版社妙佑医疗国际健康通讯 — 免费书籍 CON-20256724 患者护理和健康信息 疾病与状况 选择性免疫球蛋白 A 缺乏症