诊断

诊断 MFS 的检查和程序包括:

  • 体格检查。医务人员将询问您的症状和健康状况,检查您的身体是否有癌症的体征。
  • 影像学检查。影像学检查有助于医务人员观察癌症的大小。为此使用的一项检查是磁共振成像。您可能需要进行其他影像学检查,以寻找癌症已扩散至身体其他部位的体征。您可能要进行电子计算机断层(CT)扫描。
  • 采集组织样本进行检测。活检医疗程序包括采集可疑组织样本,以在实验室进行检测。实验室检查可探查出您是否患有癌症以及确定所患癌症的类型。要采集组织样本,医务人员有时会使用针头采集细胞。有时需要手术采集组织样本。

MFS 的诊断可能很困难,因为这种肿瘤与其他类型的癌症及其他非癌症的病症很类似。详细的影像学检查和先进的实验室检查有助于医护团队准确诊断。

治疗

MFS 的治疗通常需要手术切除癌症病灶。其他治疗方法包括放射疗法和化疗。

治疗后,MFS 可能经常复发。复发后的侵袭性更强。医生可能制定清除所有癌症细胞的治疗方案。该治疗方案更可能减少癌症的复发。

医生将根据您的具体情况来制定最佳治疗方案。影像学检查有助于治疗团队了解癌症的大小和位置。生长迅速和生长缓慢的癌症有不同的治疗方案。

外科手术

手术的目标是尽量多切除肿瘤。如果要切除所有 MFS,手术可能是唯一需要的治疗方法。

有时很难切除所有 MFS,因为这种癌症往往随着生长而不断扩散。它可能深入生长到组织中。外科医生有时看不到所有肿瘤,因此无法确保它们被切除。

过去,外科医生往往只能通过截肢去除所有肿瘤。如今,由于新治疗方法的涌现,通常不需要截肢。有时会在术前使用放射疗法和化疗来缩小肿瘤。这样会更容易切除肿瘤。

放射疗法

放射疗法利用强大的能量束来杀死癌细胞。能量束可能来自 X 线、质子和其他来源。

可以在术前进行放射治疗,以帮助缩小 MFS。也可以在术后用来杀死可能残留的任何癌细胞。

化疗

化疗是一种利用化学物质杀死癌细胞的药物疗法。它可能有助于控制快速生长的 MFS。如果 MFS 对其他治疗没有反应,可选择这种治疗方法。

准备您的预约

Make an appointment with a doctor or other healthcare professional if you have any symptoms that worry you. If your healthcare professional thinks that you might have myxofibrosarcoma, you may be referred to a specialist. Specialists who care for people with myxofibrosarcoma include:

  • Cancer doctors, called medical oncologists.
  • Surgeons who specialize in operating on people with cancer, such as orthopedic oncologists or surgical oncologists.
  • Doctors who specialize in using radiation therapy to treat cancer, called radiation oncologists.

Appointments can be short and being prepared can help. Here's some information that may help you get ready.

What you can do

When you make the appointment, ask if there's anything you need to do in advance, such as fasting before having a specific test. Make a list of:

  • Your symptoms, including any that seem unrelated to the reason for your appointment.
  • Key personal information, including major stresses, recent life changes and family medical history.
  • All medications, vitamins or other supplements you take, including the doses.
  • Questions to ask your healthcare professional.

Take a family member or friend along, if possible, to help you remember the information you're given.

For myxofibrosarcoma, some basic questions to ask your healthcare professional include:

  • Do I have cancer?
  • Do I need to have the cancer removed?
  • Do I need more tests?
  • What are my treatment options?
  • What are the potential risks for these treatment options?
  • Do any of the treatments cure my cancer?
  • Can I have a copy of my pathology report?
  • How much time can I take to consider my treatment options?
  • Are there brochures or other printed materials that I can take with me? What websites do you recommend?
  • What would happen if I choose to not have treatment?

Don't hesitate to ask other questions.

What to expect from your doctor

Your healthcare professional may ask about your symptoms, such as:

  • When did your symptoms begin?
  • Have your symptoms been continuous or occasional?
  • How severe are your symptoms?
  • What, if anything, seems to improve your symptoms?
  • What, if anything, appears to worsen your symptoms?
Dec. 04, 2024

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  1. Roland CL, et al. Myxofibrosarcoma. Surgical Oncology Clinics of North America. 2016; doi:10.1016/j.soc.2016.05.008.
  2. Goldblum JR, et al. Borderline and malignant fibroblastic/myofibroblastic tumors. In: Enzinger and Weiss's Soft Tissue Tumors. 7th ed. Elsevier; 2020. https://www.clinicalkey.com. Accessed Dec. 7, 2021.
  3. Cameron AM, et al. Management of soft tissue sarcoma. In: Current Surgical Therapy. 13th ed. Elsevier; 2020. https://www.clinicalkey.com. Accessed Feb. 15, 2022.
  4. Radaelli S, et al. Treatment strategies and outcomes of primary myxofibrosarcomas in a large patients cohort. European Journal of Surgical Oncology. 2022; doi:10.1016/j.ejso.2022.01.003.