搜索医生

Maliha Zahid, M.B.B.S., Ph.D.

  1. Cardiologist
预约门诊

出版物

  1. Lopuszynski J, Wang J, Zahid M. Beyond Transduction: Anti-Inflammatory Effects of Cell Penetrating Peptides. Molecules. 2024 Aug 29; 29 (17)
    View PubMed
  2. Sahagun DA, Lopuszynski JB, Feldman KS, Pogodzinski N, Zahid M. Toxicity Studies of Cardiac-Targeting Peptide Reveal a Robust Safety Profile. Pharmaceutics. 2024 Jan 4; 16 (1) Epub 2024 Jan 04
    View PubMed
  3. Sahagun D, Zahid M. Cardiac-Targeting Peptide: From Discovery to Applications. Biomolecules. 2023 Nov 23; 13 (12)
    View PubMed
  4. Glessner JT, Ningappa MB, Ngo KA, Zahid M, So J, Higgs BW, Sleiman PMA, Narayanan T, Ranganathan S, March M, Prasadan K, Vaccaro C, Reyes-Mugica M, Velazquez J, Salgado CM, Ebrahimkhani MR, Schmitt L, Rajasundaram D, Paul M, Pellegrino R, Gittes GK, Li D, Wang X, Billings J, Squires R, Ashokkumar C, Sharif K, Kelly D, Dhawan A, Horslen S, Lo CW, Shin D, Subramaniam S, Hakonarson H, Sindhi R. Biliary atresia is associated with polygenic susceptibility in ciliogenesis and planar polarity effector genes. J Hepatol. 2023 Aug 10. [Epub ahead of print]
    View PubMed
  5. Zahid M, Weber B, Yurko R, Islam K, Agrawal V, Lopuszynski J, Yagi H, Salama G. Cardiomyocyte-Targeting Peptide to Deliver Amiodarone. Pharmaceutics. 2023 Aug 9; 15 (8) Epub 2023 Aug 09
    View PubMed
  6. Yurko R, Islam K, Weber B, Salama G, Zahid M. Conjugation of amiodarone to a novel cardiomyocyte cell penetrating peptide for potential targeted delivery to the heart. Front Chem. 2023; 11:1220573. Epub 2023 Jul 12.
    View PubMed
  7. Gallicano GI, Fu J, Mahapatra S, Sharma MVR, Dillon C, Deng C, Zahid M. Reversing Cardiac Hypertrophy at the Source Using a Cardiac Targeting Peptide Linked to miRNA106a: Targeting Genes That Cause Cardiac Hypertrophy. Pharmaceuticals (Basel). 2022 Jul 15; 15 (7) Epub 2022 July 15
    View PubMed
  8. Teekakirikul P, Zhu W, Xu X, Young CB, Tan T, Smith AM, Wang C, Peterson KA, Gabriel GC, Ho S, Sheng Y, Moreau de Bellaing A, Sonnenberg DA, Lin JH, Fotiou E, Tenin G, Wang MX, Wu YL, Feinstein T, Devine W, Gou H, Bais AS, Glennon BJ, Zahid M, Wong TC, Ahmad F, Rynkiewicz MJ, Lehman WJ, Keavney B, Alastalo TP, Freckmann ML, Orwig K, Murray S, Ware SM, Zhao H, Feingold B, Lo CW. Genetic resiliency associated with dominant lethal TPM1 mutation causing atrial septal defect with high heritability. Cell Rep Med. 2022 Feb 15; 3 (2):100501
    View PubMed
  9. Zahid M, McCandless K, Mishra S, Stiltner J, Feldman K, Yagi H, Yurko R, Islam K, Brown J, Frizzell R. Novel Lung Targeting Cell Penetrating Peptides as Vectors for Delivery of Therapeutics. Res Sq 2021 Nov 15
    View PubMed
  10. Lopuszynski JB, Downing AJ, Finley CM, Zahid M. Prognosticators of All-Cause Mortality in Patients With Heart Failure With Preserved Ejection Fraction. Am J Cardiol. 2021 Nov 1; 158:66-73 Epub 2021 Aug 29
    View PubMed
  11. Schilling AL, Carcella AR, Moore J, Zahid M, Lo C, Wang EW, Lee SE, Little SR. Compatibility of a Thermoresponsive and Controlled Release System for Promoting Sinonasal Cilia Regeneration. Macromol Biosci. 2021 Nov; 21 (11):e2100277 Epub 2021 Aug 12
    View PubMed
  12. Stiltner J, McCandless K, Zahid M. Cell-Penetrating Peptides: Applications in Tumor Diagnosis and Therapeutics. Pharmaceutics. 2021 Jun 15; 13(6).
    View PubMed
  13. Feldman KS, Kim E, Czachowski MJ, Wu Y, Lo CW, Zahid M. Differential effect of anesthetics on mucociliary clearance in vivo in mice. Sci Rep. 2021 Mar 1; 11 (1):4896 Epub 2021 Mar 01
    View PubMed
  14. Feldman KS, Pavlou MP, Zahid M. Cardiac Targeting Peptide : From Identification to Validation to Mechanism of Transduction. Methods Mol Biol. 2021; 2211:97-112.
    View PubMed
  15. Feldman KS, Zahid M. In vivo Evaluation of Mucociliary Clearance in Mice. J Vis Exp. 2020 Dec 18; (166).
    View PubMed
  16. Zahid M, Feinstein TN, Oro A, Schwartz M, Lee AD, Lo CW. Rapid Ex-Vivo Ciliogenesis and Dose-Dependent Effect of Notch Inhibition on Ciliogenesis of Respiratory Epithelia. Biomolecules. 2020 Aug 14; 10 (8)
    View PubMed
  17. Feldman KS, Zahid M. In Vivo Imaging of Transduction Efficiencies of Cardiac Targeting Peptide. J Vis Exp. 2020 Jun 11; (160) Epub 2020 June 11
    View PubMed
  18. Taylor RE, Zahid M. Cell Penetrating Peptides, Novel Vectors for Gene Therapy. Pharmaceutics. 2020 Mar 03; 12(3).
    View PubMed
  19. Zahid M, Feldman KS, Garcia-Borrero G, Feinstein TN, Pogodzinski N, Xu X, Yurko R, Czachowski M, Wu YL, Mason NS, Lo CW. Cardiac Targeting Peptide, a Novel Cardiac Vector: Studies in Bio-Distribution, Imaging Application, and Mechanism of Transduction. Biomolecules. 2018 Nov 14; 8 (4)
    View PubMed
  20. Stewart E, Adams PS, Tian X, Khalifa O, Wearden P, Zahid M, Lo CW. Airway ciliary dysfunction: Association with adverse postoperative outcomes in nonheterotaxy congenital heart disease patients. J Thorac Cardiovasc Surg. 2018 Feb; 155 (2):755-763.e7 Epub 2017 Sept 20
    View PubMed
  21. Zahid M, Bais A, Tian X, Devine W, Lee DM, Yau C, Sonnenberg D, Beerman L, Khalifa O, Lo CW. Airway ciliary dysfunction and respiratory symptoms in patients with transposition of the great arteries. PLoS One. 2018; 13 (2):e0191605 Epub 2018 Feb 14
    View PubMed
  22. Adams PS, Zahid M, Khalifa O, Feingold B, Lo CW. Low Nasal NO in Congenital Heart Disease With Systemic Right Ventricle and Postcardiac Transplantation. J Am Heart Assoc. 2017 Dec 6; 6 (12) Epub 2017 Dec 06
    View PubMed
  23. Liu X, Yagi H, Saeed S, Bais AS, Gabriel GC, Chen Z, Peterson KA, Li Y, Schwartz MC, Reynolds WT, Saydmohammed M, Gibbs B, Wu Y, Devine W, Chatterjee B, Klena NT, Kostka D, de Mesy Bentley KL, Ganapathiraju MK, Dexheimer P, Leatherbury L, Khalifa O, Bhagat A, Zahid M, Pu W, Watkins S, Grossfeld P, Murray SA, Porter GA Jr, Tsang M, Martin LJ, Benson DW, Aronow BJ, Lo CW. The complex genetics of hypoplastic left heart syndrome. Nat Genet. 2017 Jul; 49(7):1152-1159. Epub 2017 May 22.
    View PubMed
  24. Panigrahy A, Lee V, Ceschin R, Zuccoli G, Beluk N, Khalifa O, Votava-Smith JK, DeBrunner M, Munoz R, Domnina Y, Morell V, Wearden P, Sanchez De Toledo J, Devine W, Zahid M, Lo CW. Brain Dysplasia Associated with Ciliary Dysfunction in Infants with Congenital Heart Disease. J Pediatr. 2016 Nov; 178:141-148.e1 Epub 2016 Aug 26
    View PubMed
  25. Razzak A, Smith D, Zahid M, Papachristou G, Khalid A. Effect of quality metric monitoring and colonoscopy performance. Endosc Int Open. 2016 Oct; 4(10):E1023-E1027. Epub 2016 Aug 05.
    View PubMed
  26. Gibbs BC, Damerla RR, Vladar EK, Chatterjee B, Wan Y, Liu X, Cui C, Gabriel GC, Zahid M, Yagi H, Szabo-Rogers HL, Suyama KL, Axelrod JD, Lo CW. Prickle1 mutation causes planar cell polarity and directional cell migration defects associated with cardiac outflow tract anomalies and other structural birth defects. Biol Open. 2016 Feb 16; 5 (3):323-35
    View PubMed
  27. Li Y, Yagi H, Onuoha EO, Damerla RR, Francis R, Furutani Y, Tariq M, King SM, Hendricks G, Cui C, Saydmohammed M, Lee DM, Zahid M, Sami I, Leatherbury L, Pazour GJ, Ware SM, Nakanishi T, Goldmuntz E, Tsang M, Lo CW. DNAH6 and Its Interactions with PCD Genes in Heterotaxy and Primary Ciliary Dyskinesia. PLoS Genet. 2016 Feb; 12 (2):e1005821 Epub 2016 Feb 26
    View PubMed
  28. Nakanishi T, Markwald RR, Baldwin HS, Keller BB, Srivastava D, Yamagishi H, Klena N, Gabriel G, Liu X, Yagi H, Li Y, Chen Y, Zahid M, Tobita K, Leatherbury L, Pazour G, Lo CW. Role of Cilia and Left-Right Patterning in Congenital Heart Disease Tokyo: Springer. 2016.
    View PubMed
  29. Adams PS, Tian X, Zahid M, Khalifa O, Leatherbury L, Lo CW. Establishing normative nasal nitric oxide values in infants. Respir Med. 2015 Sep; 109(9):1126-30. Epub 2015 Jul 15.
    View PubMed
  30. Li Y, Garrod AS, Madan-Khetarpal S, Sreedher G, McGuire M, Yagi H, Klena NT, Gabriel GC, Khalifa O, Zahid M, Panigrahy A, Weiner DJ, Lo CW. Respiratory motile cilia dysfunction in a patient with cranioectodermal dysplasia. Am J Med Genet A. 2015 Sep; 167A (9):2188-96 Epub 2015 Apr 25
    View PubMed
  31. Quinn SP, Zahid MJ, Durkin JR, Francis RJ, Lo CW, Chennubhotla SC. Automated identification of abnormal respiratory ciliary motion in nasal biopsies. Sci Transl Med. 2015 Aug 5; 7 (299):299ra124
    View PubMed
  32. Zahid M, Robbins PD. Cell-type specific penetrating peptides: therapeutic promises and challenges. Molecules. 2015 Jul 20; 20 (7):13055-70 Epub 2015 July 20
    View PubMed
  33. Welchering N, Ochoa S, Tian X, Francis R, Zahid M, Munoz R, Lo CW. Dexmedetomidine and fentanyl exhibit temperature dependent effects on human respiratory cilia. Front Pediatr. 2015; 3:7 Epub 2015 Feb 11
    View PubMed
  34. Garrod AS, Zahid M, Tian X, Francis RJ, Khalifa O, Devine W, Gabriel GC, Leatherbury L, Lo CW. Airway ciliary dysfunction and sinopulmonary symptoms in patients with congenital heart disease. Ann Am Thorac Soc. 2014 Nov; 11 (9):1426-32
    View PubMed
  35. Bahaa Kaseer, Jonathan Chahin, Robin Weyandt, Maliha Zahid . Lack of Association between Pneumococcal Vaccination and Outcomes in Patients Presenting with ST-Elevation Myocardial Infarction Journal of Cardiovascular Disease Research. 2014; 5(2).
  36. Christopher AB, Ochoa S, Krushansky E, Francis R, Tian X, Zahid M, Munoz R, Lo CW. The effects of temperature and anesthetic agents on ciliary function in murine respiratory epithelia. Front Pediatr. 2014; 2:111 Epub 2014 Oct 16
    View PubMed
  37. Rockacy MJ, Zahid M, McGrath KM, Fasanella KE, Khalid A. Association between KRAS mutation, detected in pancreatic cyst fluid, and long-term outcomes of patients. Clin Gastroenterol Hepatol. 2013 Apr; 11 (4):425-9 Epub 2012 Dec 23
    View PubMed
  38. Zahid M, Kapila A, Eagan CE, Yusko DA, Miller ED, Missenda CD. Prevalence and significance of electrocardiographic changes and side effect profile of regadenoson compared with adenosine during myocardial perfusion imaging. J Cardiovasc Dis Res. 2013 Mar; 4 (1):7-10 Epub 2013 Feb 27
    View PubMed
  39. Maliha , Ish, Chester, Roslyn, Michael, Ali. Associations between Pneumococcal Vaccination and Adverse Outcomes in Patients with Suspected Acute Coronary Syndrome. Advances in Infectious Diseases Advances in Infectious Diseases. 2012; 2(4).
  40. Zahid M, Robbins PD. Protein transduction domains: applications for molecular medicine. Curr Gene Ther. 2012 Oct; 12(5):374-80.
    View PubMed
  41. Zahid M, Arora S. Reverse Wenckebach "pseudo-supernormal" conduction or paroxysmal atrioventricular block. J Cardiovasc Dis Res. 2012 Jul; 3 (3):225-7
    View PubMed
  42. Kotchey NM, Adachi K, Zahid M, Inagaki K, Charan R, Parker RS, Nakai H. A potential role of distinctively delayed blood clearance of recombinant adeno-associated virus serotype 9 in robust cardiac transduction. Mol Ther. 2011 Jun; 19 (6):1079-89 Epub 2011 Mar 01
    View PubMed
  43. Zahid M, Robbins PD. Identification and characterization of tissue-specific protein transduction domains using peptide phage display. Methods Mol Biol. 2011; 683:277-89.
    View PubMed
  44. Zahid M, Phillips BE, Albers SM, Giannoukakis N, Watkins SC, Robbins PD. Identification of a cardiac specific protein transduction domain by in vivo biopanning using a M13 phage peptide display library in mice. PLoS One. 2010 Aug 17; 5 (8):e12252
    View PubMed
  45. Zahid M, Lu X, Mi Z, Robbins PD. Cationic and tissue-specific protein transduction domains identification, characterization, and therapeutic application. Adv Genet. 2010; 69:83-95.
    View PubMed
  46. Zahid M, Good CB, Sonel AF. Differential Diagnosis of Serum Cardiac Troponin Elevation: A Gold Standard for Diagnosing Acute Myocardial Injury. Chambers & Valves, the Journal of Cardiology. 2010.
  47. Zahid M, Good CB, Singla I, Sonel AF. Clinical significance of borderline elevated troponin I levels across different assays in patients with suspected acute coronary syndrome. Am J Cardiol. 2009 Jul 15; 104 (2):164-8 Epub 2009 June 03
    View PubMed
  48. Khalid A, Zahid M, Finkelstein SD, LeBlanc JK, Kaushik N, Ahmad N, Brugge WR, Edmundowicz SA, Hawes RH, McGrath KM. Pancreatic cyst fluid DNA analysis in evaluating pancreatic cysts: a report of the PANDA study. Gastrointest Endosc. 2009 May; 69 (6):1095-102 Epub 2009 Jan 18
    View PubMed
  49. Singla I, Zahid M, Good CB, Macioce A, Sonel AF. Effect of hyponatremia (<135 mEq/L) on outcome in patients with non-ST-elevation acute coronary syndrome. Am J Cardiol. 2007 Aug 1; 100 (3):406-8 Epub 2007 June 08
    View PubMed
  50. Ramani G, Zahid M, Good CB, Macioce A, Sonel AF. Comparison of frequency of new-onset atrial fibrillation or flutter in patients on statins versus not on statins presenting with suspected acute coronary syndrome. Am J Cardiol. 2007 Aug 1; 100 (3):404-5 Epub 2007 June 08
    View PubMed
  51. Sonel AF, Shalaby A, McConnell JP, Czarnecki T, Hogen S, Zahid M, Amidi M. Detectable troponin levels predict poor prognosis in patients with left ventricular dysfunction undergoing internal defibrillator implantation. Pacing Clin Electrophysiol. 2007 Jul; 30(7):839-44.
    View PubMed
  52. Singla I, Zahid M, Good CB, Macioce A, Sonel AF. Impact of blood transfusions in patients presenting with anemia and suspected acute coronary syndrome. Am J Cardiol. 2007 Apr 15; 99 (8):1119-21 Epub 2007 Feb 21
    View PubMed
  53. Nodit L, McGrath KM, Zahid M, Jani N, Schoedel KE, Ohori NP, Carty S, Finkelstein S, Khalid A. Endoscopic ultrasound-guided fine needle aspirate microsatellite loss analysis and pancreatic endocrine tumor outcome. Clin Gastroenterol Hepatol. 2006 Dec; 4 (12):1474-8 Epub 2006 Sept 25
    View PubMed
  54. Khalid A, Nodit L, Zahid M, Bauer K, Brody D, Finkelstein SD, McGrath KM. Endoscopic ultrasound fine needle aspirate DNA analysis to differentiate malignant and benign pancreatic masses. Am J Gastroenterol. 2006 Nov; 101 (11):2493-500
    View PubMed
  55. Hreybe H, Zahid M, Sonel A, Good CB, Shaver J, Saba S. Noncardiac surgery and the risk of death and other cardiovascular events in patients with hypertrophic cardiomyopathy. Clin Cardiol. 2006 Feb; 29 (2):65-8
    View PubMed
  56. Khalid A, McGrath KM, Zahid M, Wilson M, Brody D, Swalsky P, Moser AJ, Lee KK, Slivka A, Whitcomb DC, Finkelstein S. The role of pancreatic cyst fluid molecular analysis in predicting cyst pathology. Clin Gastroenterol Hepatol. 2005 Oct; 3 (10):967-73
    View PubMed
  57. Zahid M, Sonel AF, Saba S, Good CB. Perioperative risk of noncardiac surgery associated with aortic stenosis. Am J Cardiol. 2005 Aug 1; 96 (3):436-8
    View PubMed
  58. Zahid M, Sonel AF, Kelley ME, Wall L, Whittle J, Fine MJ, Good CB. Effect of both elevated troponin-I and peripheral white blood cell count on prognosis in patients with suspected myocardial injury. Am J Cardiol. 2005 Apr 15; 95(8):970-2.
    View PubMed
  59. Janczewski AM, Zahid M, Lemster BH, Frye CS, Gibson G, Higuchi Y, Kranias EG, Feldman AM, McTiernan CF. Phospholamban gene ablation improves calcium transients but not cardiac function in a heart failure model. Cardiovasc Res. 2004 Jun 01; 62(3):468-80.
    View PubMed
  60. Kollef MH, Zahid M, Eisenberg PR. Predictive value of a rapid semiquantitative D-dimer assay in critically ill patients with suspected venous thromboembolic disease. Crit Care Med. 2000 Feb; 28 (2):414-20
    View PubMed
  61. Malik IA, Zahid M, Haq S, Syed S, Moid I, Waheed I. Effect of subcutaneous injection of granulocyte-macrophage colony stimulating factor (GM-CSF) on healing of chronic refractory wounds. Eur J Surg. 1998 Oct; 164 (10):737-44
    View PubMed
  62. Aziz Z, Zahid M, Ud Din Ahmed Z, Arshad T. Phase II trial of ifosfamide and cisplatinum in advanced ovarian cancer. Aust N Z J Med. 1998 Jun; 28 (3):403-9
    View PubMed
  63. Aziz Z, Zahid M, Qazi S, Zaman H. Haemangiopericytoma of the heart: report of a case with combined modality treatment. Eur J Surg Oncol. 1997 Oct; 23 (5):459-61
    View PubMed
  64. Khalid A, Zahid M, Rehman A, Ahmad ZU, Qazi S, Aziz Z. Clinicoepidemiological features of adult leukemias in Pakistan. J Pak Med Assoc. 1997 Apr; 47 (4):119-22
    View PubMed
  65. Aziz Z, Zahid M, Mahmood R, Maqbool S. Modified BFM protocol for childhood acute lymphoblastic leukemia: a retrospective analysis. Med Pediatr Oncol. 1997 Jan; 28 (1):48-53
    View PubMed
  66. Zahid M, Khalid A, Ahmed ZD, Aziz Z. Acute leukemias of childhood: a retrospective analysis of 62 cases. J Pak Med Assoc. 1996 Jul; 46 (7):147-9
    View PubMed
PST-20549926