Departments and specialties

Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery.

Research

Mayo Clinic researchers study ways to improve care for people living with irregular heartbeats, called arrhythmias.

Mayo Clinic experts have contributed to the understanding of arrhythmia diagnosis and treatment in important ways:

  • Led a multicenter, multinational trial to compare medicine with cardiac ablation for people with irregular heartbeats.
  • Reported on the heart conditions that increase the risk of sudden death from AV node ablation in some people with AFib.
  • Designed new types of balloon devices to deliver cryoablation during catheter treatment for AFib.
  • Improved understanding of the genetics of heart arrhythmias.
  • Demonstrated how using catheters and sound waves, a technology called intracardiac ultrasound, during atrial fibrillation ablation lowers the risk of return hospital stays.

This emphasis on research and innovation increases the treatment choices available to you at Mayo Clinic. You also may have the opportunity to participate in clinical trials. Learn more about the Heart Rhythm Disease Program and the Cardiovascular Research Center at Mayo Clinic.

Publications

See a list of publications about atrial fibrillation ablation by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Research Profiles

April 09, 2024
  1. Bonow RO, et al., eds. Therapy for cardiac arrhythmias. In: Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 11th ed. Elsevier; 2019. https://www.clinicalkey.com. Accessed Feb. 2, 2021.
  2. Catheter ablation. National Heart, Lung, and Blood Institute. https://www.nhlbi.nih.gov/health-topics/catheter-ablation. Accessed Jan. 21, 2021.
  3. Zipes DP, et al., eds. Catheter ablation: Technical aspects. In: Cardiac Electrophysiology: From Cell to Bedside. 7th ed. Elsevier; 2018. https://www.clinicalkey.com. Accessed Feb. 2, 2021.
  4. Passman R, et al. Atrial fibrillation: Catheter ablation. http://www.uptodate.com/search. Accessed Dec. 18, 2023.
  5. Bonow RO, et al. Atrial fibrillation: Clinical features, mechanisms, and management. In: Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 11th ed. Elsevier; 2019. https://www.clinicalkey.com. Accessed Feb. 2, 2021
  6. January CT, et al. 2019 AHA/ACC/HRS focused update of the 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society in collaboration with the Society of Thoracic Surgeons. Circulation. 2019; doi:10.1161/CIR.0000000000000665.
  7. Wang R, et al. Sudden death and its risk factors after atrioventricular junction ablation and pacemaker implantation in patients with atrial fibrillation. Clinical Cardiology. 2017; doi:10.1002/clc.22600.
  8. Calkins H, et al. 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation. Europace. 2018; doi:10.1093/europace/eux274.
  9. Lee R. Surgical ablation to prevent recurrent atrial fibrillation. https://www.uptodate.com/contents/search. Accessed Feb. 2, 2021.
  10. Knight BP, et al. Long-term outcomes after ablation for paroxysmal atrial fibrillation using the second-generation cryoballoon: Final results from STOP AF Post-Approval Study. JACC Clinical Electrophysiology. 2019; doi:10.1016/j.jacep.2018.11.006.
  11. Noseworthy PA, et al. Atrial fibrillation ablation in practice: Assessing CABANA generalizability. European Society of Cardiology. 2019; doi:10.1093/eurheartj/ehz085.
  12. What is an arrhythmia? National Heart, Lung, and Blood Institute. https://www.nhlbi.nih.gov/health/arrhythmias. Accessed Dec. 18, 2023.
  13. Deshpande S, et al. Impact of intracardiac echocardiography on readmission morbidity and mortality following atrial fibrillation ablation. Journal of Cardiovascular Electrophysiology. 2022; doi:10.1111/jce.15683.
  14. Ami TR. Allscripts EPSi. Mayo Clinic. Sept. 24, 2023.
  15. Packer DL, et al. Effect of catheter ablation vs antiarrhythmic drug therapy on mortality, stroke, bleeding, and cardiac arrest among patients with atrial fibrillation. JAMA. 2019; doi:10.1001/jama.2019.0693.
  16. Lévy S. Overview of catheter ablation of cardiac arrhythmias. https://www.uptodate.com/contents/search. Accessed Dec. 18, 2023.
  17. Noseworthy PA (expert opinion). Mayo Clinic. Feb. 5, 2021.
  18. Rowse PG (expert opinion). Mayo Clinic. Dec. 26, 2023.

Atrial fibrillation ablation