News Sept. 10, 2024 Home rehabilitation for chronic obstructive pulmonary disease Rehabilitation for individuals with COPD is considered one of the cornerstones of therapy. Unfortunately, less than 2% of individuals complete rehab due to a variety of barriers. A new option at Mayo Clinic helps addres[...] May 08, 2024 Kefir may improve gut health of patients in the ICU Gut microbiome derangement is frequent in the ICU, potentially leading to a heightened risk of infections, organ failure, septic shock and mortality. A recent study assessed the safety, feasibility and impact of kefir a[...] Dec. 16, 2023 Shortened telomeres heighten risk of serious lung disease The 46 human chromosomes are shown in blue, with the telomeres appearing as white pinpoints. The DNA has already been copied, so each chromosome is made up of two identical lengths of DNA, each with its own two telomeres. [...] Dec. 06, 2023 Advancing science through medical education Within Pulmonary and Critical Care Medicine at Mayo Clinic, educators and developing education scientists are honing their craft — leading to groundbreaking initiatives aimed to enhance understanding and practice [...] Sept. 27, 2023 Respiratory complications of hematopoietic stem cell transplantation Hematopoietic stem cell transplantation (HCT) is a potentially curative and lifesaving treatment option for hematologic cancers such as leukemia, lymphoma and myeloma. While other aspects of post-HCT care have improved,[...] Sept. 27, 2023 Mayo Clinic's Center for Sleep Medicine One of the largest sleep medicine facilities in the U.S., Mayo Clinic's Center for Sleep Medicine offers more comprehensive and accurate diagnosis and treatment plans for a broader range of patients. Sept. 07, 2023 A more accurate lung nodule biopsy: Combining shape-sensing bronchoscopy with mobile 3D imaging CT-to-body divergence is a challenge in lung cancer diagnosis via bronchoscopy. By combining mobile 3D imaging with shape-sensing robotic-assisted bronchoscopy, Mayo Clinic researchers achieve tool-in-lesion in 96.7% of[...] Aug. 26, 2023 Science Saturday: When sleep disorders presage something more serious Early one morning, while checking on a slumbering patient at the Center for Sleep Medicine, Erik St. Louis, M.D., noticed something peculiar. The patient, a woman in her early 60's, had started running beneath her bed[...] May 11, 2023 Overcoming language barriers to optimize patient care Health care disparities, in particular language barriers, can impact complex medical care and patient care during critical illness and at the end of life. April 27, 2023 Lung cancer care advancements in the American Southwest Mayo Clinic experts have transformed clinical care for patients with lung cancer. With more screening options and less invasive surgical options, patients with lung cancer can have improved outcomes. Dec. 17, 2022 Lung transplant program at Mayo Clinic Under the joint leadership of Cassie C. Kennedy, M.D., and Mauricio A. Villavicencio Theoduloz, M.D., the Mayo Clinic Lung Transplant Program focuses on improving referral to waitlist decision efficiency and maintaining[...] Sept. 10, 2022 Treating patients experiencing post-ICU syndrome The Mayo Clinic ICU Recovery Program (MCIRP) continues to offer fully virtual appointments to help practitioners develop a comprehensive recovery plan. July 29, 2022 Geographical allocation changes boost heart and lung transplant program at Mayo Clinic in Minnesota An expanded geographical reach with the 2017 to 2018 U.S. heart and lung transplant allocation changes has prompted significant program expansion at Mayo Clinic's Minnesota campus. July 14, 2022 Technology, AI advancements in pediatric asthma care Virtual DOT records short, time-stamped videos of patients taking each dose of a prescribed inhaler. These recordings help health care providers correct and improve inhaler technique for optimal results. July 14, 2022 Tracheal wedge excision for pediatric idiopathic tracheal stenosis (PITS) A multidisciplinary team at Mayo Clinic Children's Center provides comprehensive diagnostic and treatment services for children with PITS, a rare disease that [...] March 30, 2022 Steroid use in pneumonia Novel strategies that consider patient-specific variables, including markers of inflammation, may result in an individualized approach to corticosteroid use in the treatment of patients with community-acquired pneumonia[...] March 30, 2022 Potential novel treatments for advanced-stage lung cancer Mayo Clinic participates in multiple neoadjuvant immunotherapy trials to better assess response rates and enhance operability in patients with advanced-stage lung cancer. Dec. 28, 2021 Right-fit care for patients with severe lung disease: From clinical trials to transplant A lung transplant surgeon discusses Mayo Clinic's collaboration with local physicians to determine the best treatment for each patient, including transplant, clinical trials or other therapies, or transplant prehabilita[...] Dec. 03, 2021 Clinical decision support systems for personalized management of patients with acute kidney injury Advances in digital health techniques provide tremendous opportunities to improve the care of patients at risk of or with acute kidney injury or its related complications. Dec. 03, 2021 New frontiers in the treatment of COPD Treatment for patients with chronic obstructive pulmonary disease (COPD) — including emphysema, chronic bronchitis and COPD exacerbation — can be tailored to each patient's phenotype. Aug. 11, 2021 Organ perfusion systems a boon to heart and lung transplants Transplant specialists at Mayo Clinic in Florida use organ perfusion systems for some heart and lung transplants, resulting in multiple advantages for recipients — including saving lives. July 31, 2021 New treatment options for patients with obstructive sleep apnea who are intolerant to positive airway pressure therapy Mayo Clinic offers upper airway stimulation therapy, oral appliance therapy and the expertise of a sleep surgeon for patients who are positive airway pressure (PAP) therapy intolerant. July 31, 2021 Establishing the pulmonary oncologic toxicity clinic to care for patients with lung toxicity Mayo Clinic Pulmonary and Critical Care Medicine is establishing a pulmonary oncologic toxicity clinic to care for patients with lung toxicity from chemotherapy, radiation and immunotherapy. July 31, 2021 Pulmonary function laboratories offer comprehensive testing services with advanced diagnostics Mayo Clinic pulmonary function laboratories' updated infection control practices in response to COVID-19 allowed needed testing services to reopen quickly and personal protective measures to be de-escalated safely. April 03, 2021 Expiratory central airway collapse is challenging to identify and underdiagnosed Dynamic flexible bronchoscopy is the diagnostic criterion standard for expiratory central airway collapse, which can coexist with and mimic asthma, chronic obstructive pulmonary disease and bronchiectasis. April 03, 2021 Mayo Clinic Pulmonary and Critical Care Medicine's commitment to clinical practice excellence, education enhancement and research advancement Mayo Clinic is one of the few U.S. centers experienced in successful performance of balloon pulmonary angioplasties for patients with nonoperable chronic thromboembolic pulmonary hypertension. April 03, 2021 Cough Clinic employs novel pharmacologics to address unexplained or refractory chronic cough Mayo Clinic Cough Clinic specialists research and employ novel pharmacologic treatments and collaborate with Otolaryngology colleagues to address frustrating unexplained or refractory chronic cough. Nov. 19, 2020 Patient-specific airway stents created using 3D printing technology Mayo Clinic is one of the first centers to offer patients with complex central airway stenosis patient-specific, customized airway stents approved by the Food and Drug Administration. April 23, 2020 Regenerative medicine in lung diseases Research supports that it is safe and feasible to provide cell therapy intravenously to lung transplant recipients who have developed chronic lung allograft dysfunction. April 03, 2020 Update on ICU sedation At Mayo Clinic, the mechanical ventilation order set in the ICU no longer includes mandatory use of sedative medications. April 03, 2020 The gut-lung axis: Intestinal microbiota and inflammatory lung disease In this Q and A, Mayo Clinic pulmonologist Joseph H. Skalski, M.D., discusses research into intestinal bacterial and fungal microbiota in patients with obstructive disease phenotypes. April 03, 2020 Mayo Clinic on the path to personalization of mechanical ventilation As mortality improvements in acute respiratory distress syndrome have stagnated and the concept of safe ventilation continues to evolve, the search for better and more-integrative therapeutic targets has ensued. April 03, 2020 Home sleep apnea test simplifies diagnosing obstructive sleep apnea Mayo Clinic Center for Sleep Medicine innovation reduces the time and effort patients expend in obtaining accurate diagnoses and personalized treatment plans for obstructive sleep apnea. Feb. 25, 2020 Molecular Detection for Tuberculosis Drug Resistance [A Test in Focus] Mayo Clinic Laboratories' whole-genome sequencing testing provides molecular detection of well-characterized drug resistance variants in Mycobacterium tuberculosis complex by sequencing Mycobacterium tuberculosis isolat[...] Dec. 10, 2019 Researchers discover distinct pathways in lung adenocarcinoma Discovery of distinct pathways in lung adenocarcinoma may help improve targeted cancer therapies: Mayo Clinic Forefront cancer magazine. Oct. 18, 2019 Updates in interstitial lung disease: Current facets of anti-fibrotic therapy Teng Moua, M.D., discusses recent clinical trials and current research into the treatment of idiopathic pulmonary fibrosis (IPF) and non-IPF-progressive interstitial lung diseases. Oct. 15, 2019 Management of fibrosing mediastinitis Specialists at Mayo Clinic have used off-label rituximab to treat nearly 30 patients with fibrosing mediastinitis successfully. Disease progression was almost universally halted and two-thirds of the patients improved s[...] Oct. 15, 2019 Advancing care in chronic obstructive pulmonary disease Mayo Clinic's home-based pulmonary rehabilitation program provides patients who have chronic obstructive pulmonary disease (COPD) with a health coach and a computer-guided activity and monitoring program. Oct. 15, 2019 Ion robotic bronchoscopy system the focus of a multicenter trial Mayo Clinic has joined five other medical centers to conduct a multicenter trial, enrolling 300 patients to prospectively evaluate the use of a robotic bronchoscopy system. Oct. 15, 2019 Pediatric sleep medicine integrates with multidisciplinary clinics to facilitate communication and treatment Mayo Clinic's Center for Sleep Medicine team provides multidisciplinary care for children in special populations or with medically complex needs. April 19, 2019 Bronchoscopic lung volume reduction therapy approved for severe emphysema Bronchoscopic lung volume reduction has emerged as a potential alternative to lung volume reduction surgery and a less invasive method by which to achieve lung volume reduction in patients with emphysema and hyperinflat[...] Jan. 11, 2019 Update on the management of ANCA-associated vasculitis Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis comprises three syndromes, all with frequent respiratory manifestations. Studies indicate that ANCA specificity is more important for prognosis, relapse [...] Jan. 08, 2019 Multidisciplinary care of idiopathic subglottic stenosis A combined approach of inhaled glucocorticoids, trimethoprim-sulfamethoxazole, and proton-pump inhibitors plus lifestyle modifications for the treatment of idiopathic subglottic stenosis (ISS) suggests that ISS recurs l[...] Jan. 08, 2019 Update in pleural disease This update addresses some of the latest understanding and approaches to management of malignant pleural disease, including use of the RAPID multistep scoring system to better predict prognosis in those patients who pre[...] Jan. 08, 2019 Anti-interleukin-5 therapy for severe asthma: A new therapeutic option Anti-interleukin-5 therapy is approved for patients with refractory asthma with an eosinophilic phenotype. The severe asthma care team at Mayo Clinic has expertise in identifying appropriate patients for this step-up th[...] Jan. 08, 2019 Cone-beam CT for enhanced bronchoscopic access to pulmonary nodules Interventional pulmonologists and thoracic surgeons are exploring the use of cone-beam CT during bronchoscopy. Cone-beam CT image quality is sufficient for localizing pulmonary nodules, with the added benefit of real-ti[...] Sept. 12, 2018 Lung transplantation: Challenges and opportunities Mayo Clinic and United Therapeutics Corp. are furthering the study of ex vivo lung perfusion and ventilation to resuscitate and support donor lungs that would otherwise be unavailable for transplant. Sept. 12, 2018 Anti-fibrotic therapy in the treatment of IPF: Ongoing concerns and current practices Pirfenidone and nintedanib are approved for treatment of idiopathic pulmonary fibrosis (IPF), but questions remain regarding indications and timing of initiation, side effects, and long-term outcomes. Sept. 12, 2018 New definitions and diagnoses in interstitial pneumonia While interstitial pneumonias have been studied and recognized over several decades, a new classification system provides a more intuitive organization of both the prevalence and natural course of specific histologic pa[...] Feb. 10, 2018 Maxillomandibular advancement surgery: A classic procedure refined MMA should be considered for any patient with moderate to severe obstructive sleep apnea if surgical management is desired. At Mayo Clinic, more than half of patients with obstructive sleep apnea achieve elimination (ap[...] Feb. 10, 2018 The gaining popularity of oral appliances Oral appliances can improve important outcomes in selected patients with more severe obstructive sleep apnea (OSA). Innovations include compliance recorders to help in long-term follow-up and emerging technologies to re[...] Feb. 10, 2018 The emerging option of upper airway stimulation therapy Activation of the genioglossus muscle via stimulation of the hypoglossal nerve is a new approach for treatment of obstructive sleep apnea (OSA). In a 2014 study, stimulation was associated with a 68 percent reduction in[...] Feb. 09, 2018 Care of the patient with lung cancer at Mayo Clinic: Mayo Clinic tumor board provides multidisciplinary expertise The multidisciplinary assembly provides up-to-date treatment options for patients with lung cancer, explores enrollment in clinical trials, and enhances cross-discipline education from the exchange of information and ex[...] Feb. 09, 2018 Advances in lung cancer immunotherapy and management of immune-mediated adverse events A new study explores the combination of the intratumoral administration of the measles virus with systemic PD-L1 targeted immunotherapy using atezolizumab for second line therapy of non-small cell lung cancer. Jan. 20, 2018 Noninvasive radiologic biomarkers to individualize lung cancer therapy Computer-Aided Nodule Assessment and Risk Yield (CANARY) image analysis software has shown promise in noninvasively predicting epithelial growth factor receptor (EGFR) status of adenocarcinoma of the lung, allowing for [...] Feb. 26, 2016 Transbronchial cryobiopsy in diffuse parenchymal lung disease Mayo pulmonary specialists have evaluated the use of cryobiopsies in selected patients with diffuse parenchymal lung diseases for several years. Advantages include the ability to collect much larger specimens while pres[...] March 03, 2015 Mayo Clinic's Cystic Fibrosis Foundation-designated CF care center Mayo's Cystic Fibrosis Center specializes in the care of pediatric and adult patients - Cystic fibrosis is the most common genetic disease of Caucasians. Expected survival has increased to 38-plus years, thanks to adher[...] Medical Professionals Pulmonary, Critical Care, & Sleep Medicine News