Clinical Trials Below are current clinical trials.66 studies in Pulmonary, Critical Care, and Sleep Medicine (open studies only). Filter this list of studies by location, status and more. A Study to Evaluate the Use of a Smartphone App for Stroke Patients with Obstructive Sleep Apnea Rochester, Minn. The purpose of this study is to evaluate the use of a smartphone app for stroke patients with obstructive sleep apnea in order to better use their positive airway pressure (PAP) therapy. A Study of Patients Undergoing Neoadjuvant Therapy for Resectable Non-small Cell Lung Cancer to Evaluate Perioperative Circulating Tumor DNA as a Prognostic Biomarker Jacksonville, Fla. The purpose of this study is to determine the validity of employing quantitative ctDNA as a surrogate marker for pathologic treatment response in patients receiving neoadjuvant therapy for Stage IIA-IIIB NSCLC undergoing curative-intent resection. We will assess the relationship between major pathologic response (≤10% viable tumor remaining) and percent change in levels of ctDNA concentration before and after neoadjuvant therapy. Rivet PVS Therapy in Group 2C Rochester, Minn. The purpose of this study is to evaluate the safety, performance, and initial clinical efficacy of the Rivet PVS therapy in patients with symptomatic pulmonary hypertension. A Multimodal Monitoring (MMM) Computer to Detect Physiologic Trends in Data in Neurointensive Care Unit Patients Rochester, Minn., Jacksonville, Fla. The purpose of this study is to identify important physiologic trends in bedside ICU data such as cerebral perfusion pressure (CPP), intracranial pressure (ICP) using a bedside “Multimodal monitoring” (MMM) computer which utilizes ICM+ Cambridge software. A Prospective Registry for Patients with REM Sleep Behavior Disorder and Polysomnographic REM Sleep without Atonia and Controls Rochester, Minn. The purpose of this study is to follow patients with REM sleep behavior disorder (RBD) over time and learn which types of RBD patients may be at risk of developing other diseases. Assessment of the Mechanical Properties of Lung Parenchyma using Magnetic Resonance Elastography Rochester, Minn. The purpose of this research study is testing a new technique for measuring stiffness of the lung. This new technique is called Magnetic Resonance Elastography (MRE). In this study we will look at the stiffness measurements in humans. Creation of a Longitudinal Biospecimen Repository From Patients With Interstitial Lung Diseases (ILD) Rochester, Minn. To develop a repository of blood, urine and tissue samples from patients with ILD to support future studies into the development of such biomarkers. A Study to Evaluate the Safety, Tolerability, and Determine the Optimal Dose for the Expansion Cohorts of VSV-IFNβ-NIS in Combination with Pembrolizumab in Patients with Refractory Solid Tumors Rochester, Minn. The purpose of this study is to determine the safety of VSV-IFNβ-NIS in combination with pembrolizumab, followed by expansion to examine effectiveness of combination therapy in patients with refractory Non-Small Cell Lung Cancer (NSCLC) or Hepatocellular Carcinoma (HCC). Detection of Vascular and Inflammatory Plasma Biomarkers in Patients Diagnosed with Obstructive Sleep Apnea and MRI-defined Cerebral Small Vessel Disease Jacksonville, Fla. The purpose of this study is to evaluate plasma biomarkers of vascular function and inflammation in patients with newly-diagnosed Obstructive Sleep Apnea (OSA) and pre-existing imaging evidence of Cerebral Small Vessel Disease (CSVD). A Study to Assess Frailty and Its Impact on Patients with Pulmonary Hypertension Rochester, Minn. The purpose of this study is to evaluate the prevalence and effect of frailty in patients referred to pulmonary hypertension (PH) clinic at our institution. Pagination Clinical studies PrevPrevious Page Go to page 22 Go to page 33 Go to page 44 Go to page 55 Go to page 66 NextNext Page Medical Professionals Pulmonary, Critical Care, & Sleep Medicine Clinical Trials