Orthopedic Surgery

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. Comparative Effectiveness of Pulmonary Embolism Prevention After Hip and Knee Replacement

   Rochester, Minn.

   PEPPER is a randomized study comparing the three most commonly used anticoagulants in North America in patients who have elected to undergo primary or revision hip or knee joint replacement surgery. The anticoagulants being compared are enteric coated aspirin, low intensity warfarin, and rivaroxaban.

2. A Study to Evaluate Outcomes of Rotator Cuff Repair

   Rochester, Minn.

   The purpose of this study is evaluate the outcomes and complications in patients who underwent a rotator cuff repair.

3. Scoliosis Shared Decision Making

   Rochester, Minn.

   Analysis of video encounters between providers, patients, and families will be used to develop a shared decision making tool for patients deciding between surgery and observation for scoliosis treatment.

4. A Study to Investigate the Use of Diaphragm Muscle Ultrasound to Assess the Duration of a Diaphragm Nerve Block

   Rochester, Minn.

   The purpose of this study is to to determine the impact of anesthesia (liposomal bupivacaine) on diaphragm muscle forces using a non-invasive ultrasonographic shear wave elastography (SWE) method.  

5. Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)

   Rochester, Minn., Minneapolis, Minn.

   The purpose of this study is to evaluate the continued safety and probable benefit of the MID-C system for 5 years post-implantation in Adolescent Idiopathic Scoliosis (AIS).

6. A Study to Collect Clinical Outcomes of Anatomic and Reverse Total Shoulder Arthroplasty

   Scottsdale/Phoenix, Ariz.

   The purpose of the study is a multi-center prospective registry to collect clinical outcomes of anatomic and reverse total shoulder arthroplasty.

7. A Study of the Baseball Swing Through Motion Capture

   Rochester, Minn.

   The primary aim of this study is to develop a deeper understanding of the kinetics and kinematics of the baseball swing.  Secondary aims include: describing the relative stress/forces across major lower extremity joints and spine during the baseball swing, assessing the intra- and inter-batter variability in the swing, determining how kinetics/kinematics vary across different batting scenarios, determining how kinetics/kinematics vary across different batting efforts, correlating swing kinetics with bat velocity, correlating swing kinetics with ball exit velocity, assessing the validity and reliability of various wearable devices compared to motion capture, determining the impact of bat weight on swing kinetics/kinematics, determining the impact of ball weight on swing kinetics/kinematics, assessment of eye tracking, and comparison of male baseball swing to female softball swing.

    

    

   Traditionally, batting mechanics have been analyzed qualitatively during direct observation or by viewing video tapes of batting motions.  More recently, sophisticated motion analysis systems have facilitated the collection of quantitative, three-dimensional kinematic information of the batting motion.  These advancements provide the opportunity for more detailed analyses of batting motions that can be integrated into the evaluation and treatment of baseball batters at the Mayo Clinic, with the hypothesis that metrics gathered from the force plates and motion capture are more reliable than the Motus wearables.

    

8. A Study to Assess Upper Extremity Function Using a Powered Exoskeleton

   Rochester, Minn.

   The goal of the proposed study is to develop and validate a myoelectrically-controlled power-assist upper extremity exoskeleton (powered exoskeleton) to assist with upper extremity motion in patients with traumatic peripheral nerve injuries who have inadequate motor function.

9. Does the Critical Shoulder Angle Influence the Rotator Cuff Failure After Anatomic Shoulder Arthroplasty?

   Rochester, Minn.

   The purpose of this study is to:

   • Evaluate the influence of the critical shoulder angle (CSA) on outcomes after total anatomic shoulder arthroplasty; and
   • Evaluate the influence of the critical shoulder angle (CSA) on rotator cuff failure after total anatomic shoulder arthroplasty.

10. A Study to Assess Biomarkers in Patients with Osteonecrosis of the Femoral Head

    Rochester, Minn.

    The purposes of this study is to isolate RNA from bone tissues from ONFH and osteoarthritis (OA) femoral heads and perform RNA sequencing to measure gene expression.