Neostigmine (Injection Route)

Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

1. Blurred or loss of vision
2. chest pain, discomfort, or tightness
3. confusion
4. difficult or labored breathing
5. dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
6. fast, slow, pounding, or irregular heartbeat or pulse
7. lightheadedness, dizziness, or fainting
8. sweating
9. twitches of the muscle visible under the skin
10. unusual tiredness or weakness

Incidence not known

1. Changes in patterns and rhythms of speech
2. cough
3. difficulty in moving
4. difficulty swallowing
5. disturbed color perception
6. double vision
7. halos around lights
8. hives
9. irregular, fast or slow, or shallow breathing
10. itching
11. loss of consciousness
12. muscle cramps and spasms
13. muscle pain or stiffness
14. night blindness
15. no blood pressure or pulse
16. noisy breathing
17. overbright appearance of lights
18. pain in the joints
19. pale or blue lips, fingernails, or skin
20. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
21. seizures
22. skin rash
23. slurred speech
24. stopping of the heart
25. trouble in speaking
26. tunnel vision
27. unconsciousness

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of Overdose

1. Constipation
2. decreased sexual ability
3. difficult urination
4. dry mouth
5. enlarged pupils
6. muscle weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

1. Bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at site
2. drowsiness
3. headache
4. increased watering of the mouth
5. nausea
6. sleeplessness
7. sore throat
8. trouble sleeping
9. unable to sleep
10. vomiting

Incidence not known

1. Bloated
2. constricted, pinpoint, or small pupils (black part of eye)
3. diarrhea
4. dry mouth
5. excess air or gas in the stomach or intestines
6. feeling of warmth
7. full feeling
8. increase in mucous from the lungs
9. increased need to urinate
10. increased sweating
11. passing gas
12. passing urine more often
13. redness of the face, neck, arms and occasionally, upper chest
14. redness of the skin
15. skin rash
16. stomach cramps

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

• Precautions

Portions of this document last updated: June 01, 2024

Copyright: © Merative US L.P. 1973, 2024. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.