Ensayos clínicos A continuación, se enumeran los ensayos clínicos actuales.92 estudios en Medicina cardiovascular (solo estudios abiertos). Filtra esta lista de estudios por sede, estatus, etc. A Study to Evaluate Breathing Muscle Training in Cardiac Rehab Rochester, Minn. We are currently enrolling both healthy volunteers and people who have been diagnosed with heart failure to participate in our research study. The purpose of this study is to better understand the relationship between exercise, breathing, blood flow and blood pressure. This study includes two study visits if you are a healthy or heart failure volunteer. All testing will be performed at our testing center at St. Mary’s Hospital located in Rochester, MN. On the first study visit, the research activities will be discussed and all questions will be answered. Once written consent is provided and the participant is enrolled, lung function and exercise capacity will be measured. The second study visit includes two separate breathing muscle workouts (a light and moderate workload) each followed by 10 min of light to moderate cycling exercise. In addition, two breathing tests will also be performed. During this visit, blood is drawn during exercise. If you are a patient at Mayo Clinic, who is currently enrolled or will be enrolling in a cardiac rehabilitation exercise program, you will have the option to complete four study visits. Your first two study visits as described above will be completed at the beginning of cardiac rehabilitation and then we will ask you to return to complete those same two study visits following the completion of your cardiac rehabilitation program. Remuneration and parking reimbursement are provided. Acoustic Spectrograms and Detection of Early LVAD Thrombosis Rochester, Minn. The purpose of this study is to characterize the acoustic features of normal left ventricular assist device (LVAD) pump function using spectrography and fast Fourier transformation. The study will also identify abnormalities seen in the acoustic spectrograms of those patients presenting with LVAD thrombosis. Furthermore, the study aims to follow patients where abnormalities are seen in order to ascertain which features are predictive of the development of pump thrombosis and may be considered early markers thereof. A Study of Autoimmune Functions in Patients with Myocarditis Jacksonville, Fla. The purpose of this research is to study immune cells called T cells and monocytes (types of blood cells that fight infection and can also cause autoimmune disease) that may damage heart tissue during myocarditis (inflammation of the heart muscle). Cytokines (proteins that send signals between cells) found in the blood will be studied for their effects on blood immune cells to better understand how they can lead to heart failure during and after myocarditis. Spontaneous Coronary Artery Dissection: Case Review Rochester, Minn. Spontaneous coronary artery dissection (SCAD) is uncommon but important cause of acute coronary syndrome and sudden cardiac death. There is very little data exists in regards to patient clinical characteristics, risk factors, treatment and outcomes. Our objective is to prospectively assess long term outcomes. A Study to Develop A Familial Hypercholesterolemia Identification REgistry (FHIRE) Rochester, Minn. The purpose of this study is to develop a registry of molecularly confirmed Familial Hypercholesterolemia (FH) cases in conjunction with the retrospective FHIRE study (IRB# 18-009654) in order to identify and offer genetic testing to Mayo Clinic patients with suspected FH. A Study of In Vitro Mapping of Cardiac Tissue Obtained from Patients with Refractory Arrhythmias who Underwent Heart Transplant or Replacement with Mechanical Heart Rochester, Minn. The purpose of this study is to obtain electro-anatomic maps of human myocardium in sinus rhythm and ventricular arrhythmias to identify activation patterns, identify and perform tissue ablation at targeted sites of interest that could play an important trigger for development of arrhythmias, and to perform histologic analysis of the myocardial tissue to identify triggers and/or targets for therapies to terminate ventricular arrhythmias. A Study to Evaluate Noninvasive Ultrasound Elastography of Kidney and Lung in Assessment of Volume Status in ICU Patients Rochester, Minn. The primary purpose of this study is to assess the feasibility of performing lung and kidney and lung ultrasound elastography among patients with critical illness from different etiologies that could be associated with volume overload. Ventricular Remodeling and Myocardial Deformation in Patients Undergoing Chemotherapy for Sarcomas Rochester, Minn. The aim of this study is to determine if there is subclinical systolic or diastolic myocardial mechanical dysfunction by 2D and 3D speckle tracking echocardiography derived strain and strain rate in this patient population at baseline, during and after chemotherapy. This could be an early marker of myocardial dysfunction in patients treated for sarcoma. Patient-Specific Induced Pluripotent Stem Cell Models for Heritable Channelopathies and Cardiomyopathies Rochester, Minn. The purpose of this study is to derive and characterize patient-specific disease models for sudden death-predisposing heritable channelopathies and cardiomyopathies using iPS-cell technology. It is hoped that the molecular, cellular, and electrophysiological phenotypes of these in-vitro disease models will further elucidate the pathophysiologic mechanisms underlying these sudden death-associated conditions. A Study of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction Jacksonville, Fla. The purpose of this study is to establish a registry that will address the data gap regarding the course of NSTEMI (Non-ST-Elevation Myocardial Infarction) between ED (Emergency Department) arrival and diagnostic angiography in detail, by characterizing and following the ED and peri-ED use of advanced OAP (Oral Anti-Platelet) agents. In addition to exploring ED treatment patterns and success of both ischemic and bleeding risk stratification prior to definition of the coronary anatomy, data generated via the UPSTREAM registry will allow plausible attribution of ischemic and bleeding outcomes to pre-catheterization antiplatelet therapy in the management of NSTEMI. This registry further seeks to demonstrate that contemporary use of upstream ticagrelor is associated with an economically-sound utilization of hospital resources, and smooth transition of care into the outpatient, secondary prevention setting for the first 30 days after hospitalization. Finally, it will allow characterization of patient selection factors and processes for ticagrelor vs alternative OAP agents, carrying out that descriptive comparison through discharge. Patients transferred in to an UPSTREAM hospital are eligible for inclusion, but the timing for OAP agent administration and diagnostic catheterization begin with ED care at the first hospital. Numeración de páginas Estudios clínicos AnteriorPágina anterior Ir a página 66 Ir a página 77 Ir a página 88 Ir a página 99 Ir a página 1010 SiguientePróxima página Solicite una consulta Conocimientos y categoríasInvestigación March 16, 2024 Comparte en: FacebookTwitter U.S. News & World Report reconoce a Mayo Clinic de Rochester, Minnesota, como uno de los mejores hospitales del país para cardiología y cirugía cardíaca en el período 2024-2025. Obtén más información sobre este gran honor Medicina cardiovascularPágina inicialdel departamentoSeccionesDescripción generalSolicita una consultaAnálisis y procedimientosAfecciones cardiovasculares que se tratanMédicosGrupos especializadosConocimientos y categoríasEnsayos clínicosInvestigaciónHistorias de pacientesCostos y seguroNoticias de Mayo ClinicRemisiones Investigación: los pacientes son la prioridad Mostrar la transcripción Para video Investigación: los pacientes son la prioridad [SUENA MÚSICA] Dr. Joseph Sirven, profesor de Neurología, Mayo Clinic: La misión de Mayo se centra en el paciente. La prioridad es el paciente. Aquí, la misión y la investigación se hacen para progresar en la forma de ayudar mejor al paciente y para asegurarnos de que el paciente sea la prioridad en la atención médica. De muchas maneras, esto equivale a un ciclo. Puede comenzar con algo tan simple como una idea que se desarrolla en un laboratorio, se traslada a la atención directa del paciente y, si todo sale bien y resulta útil o beneficioso, pasa a ser el método estándar. Creo que una de las características tan singulares de la forma de investigar en Mayo es la concentración en el paciente, y es lo que realmente le ayuda a captar la atención de todos. SeccionesSolicita una consultaDescripción generalAnálisis y procedimientosAfecciones cardiovasculares que se tratanMédicosGrupos especializadosConocimientos y categoríasEnsayos clínicosInvestigaciónHistorias de pacientesCostos y seguroNoticias de Mayo ClinicRemisiones ORG-20121929 Centros y departamentos médicos Medicina cardiovascular