Breast Cancer Risk Assessment Tool for Women With Benign Breast Disease (BBD)

The BBD/AH-BC model predicts the risk of developing future breast cancer for women after a breast biopsy showing benign findings, including atypical hyperplasia. The result of the model can be used to help providers and patients choose among options for surveillance and prevention of breast cancer.

Calculating Results

This calculator is intended for use by health care providers. The results should not be used alone to determine medical treatment. This tool is a statistical model and is not a substitute for an individual treatment plan developed by a health care provider with personal knowledge of a specific patient. Factors such as medical history and the health care provider’s experience, knowledge, and training must also be considered. Results should be discussed with patients when presenting prognoses or treatment recommendations.

To begin, please enter the patient's age at her benign biopsy

years

Please choose from the following categories.

live births
years

None indicates no involuted terminal duct lobular units (TDLUs) are involuted; partial indicates 1-74% TDLUs are involuted; complete indicates >75% TDLUs are involuted.

Patient Details

45 year old patient and family history of breast cancer including the following parameters:

Risk of breast cancer (%)

Years from now Individual Risk Population Average
5 years
10 years
15 years
20 years
25 years
30 years
Print Results

Details regarding the development and validation of this tool are provided in the following two manuscripts:

"Model for Individualized Prediction of Breast Cancer Risk After a Benign Breast Biopsy" (V. Shane Pankratz, Amy C. Degnim, Ryan D. Frank, Marlene H. Frost, Daniel W. Visscher, Robert A. Vierkant, Tina J. Hieken, Karthik Ghosh, Yaman Tarabishy, Celine M. Vachon, Derek C. Radisky, and Lynn C. Hartmann, Journal of Clinical Oncology 2015, 33, 923-929).

“Model for Predicting Breast Cancer Risk in Women With Atypical Hyperplasia” (Amy C. Degnim, Stacey J. Winham, Ryan D. Frank, V. Shane Pankratz, William D. Dupont, Robert A. Vierkant, Marlene H. Frost, Tanya L. Hoskin, Celine M. Vachon, Karthik Ghosh, Tina J. Hieken, Jodi M. Carter, Lori A. Denison, Brendan Broderick, Lynn C. Hartmann, Daniel W. Visscher, and Derek C. Radisky, Journal of Clinical Oncology 2018, 36, 1840-1846).

April 20, 2022

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