Publicaciones Imprimir Zadeh G, Nassiri F. Molecular classification predicts response to surgery and radiotherapy. Neuro Oncol. 2025 Jan 12; 27 (1):3-4 View PubMed Landry AP, Wang JZ, Liu J, Patil V, Gui C, Patel Z, Ajisebutu A, Ellenbogen Y, Wei Q, Singh O, Sosa J, Mansouri S, Wilson C, Cohen-Gadol AA, Zaazoue MA, Tabatabai G, Tatagiba M, Behling F, Barnholtz-Sloan JS, Sloan AE, Chotai S, Chambless LB, Rebchuk AD, Makarenko S, Yip S, Mansouri A, Tsang DS, Aldape K, Gao A, Nassiri F, Zadeh G, International Consortium on Meningiomas (ICOM). Development and validation of a molecular classifier of meningiomas. Neuro Oncol. 2025 Jan 8 Epub 2025 Jan 08 View PubMed Lee JJY, Tao R, You Z, Haldipur P, Erickson AW, Farooq H, Hendriske LD, Abeysundara N, Richman CM, Wang EY, Das Gupta N, Hadley J, Batts M, Mount CW, Wu X, Rasnitsyn A, Bailey S, Cavalli FMG, Morrissy S, Garzia L, Michealraj KA, Visvanathan A, Fong V, Palotta J, Suarez R, Livingston BG, Liu M, Luu B, Daniels C, Loukides J, Bendel A, French PJ, Kros JM, Korshunov A, Kool M, Chico Ponce de Leon F, Perezpena-Diazconti M, Lach B, Singh SK, Leary SES, Cho BK, Kim SK, Wang KC, Lee JY, Tominaga T, Weiss WA, Phillips JJ, Dai S, Zadeh G, Saad AG, Bognar L, Klekner A, Pollack IF, Hamilton RL, Ra YS, Grajkowska WA, Perek-Polnik M, Thompson RC, Kenney AM, Cooper MK, Mack SC, Jabado N, Lupien M, Gallo M, Ramaswamy V, Suva ML, Suzuki H, Millen KJ, Huang LF, Northcott PA, Taylor MD. ZIC1 is a context-dependent medulloblastoma driver in the rhombic lip. Nat Genet. 2025 Jan; 57 (1):88-102 Epub 2025 Jan 03 View PubMed Riviere-Cazaux C, Keough MB, Zuccato JA, Kumar R, Schulz S, Warrington AE, Ruff MW, Ellingson BM, Sanai N, Campian JL, Kizilbash SH, Parney IF, Zadeh G, Khasraw M, Kessler T, Sener U, Cahill DP, Mansouri A, Burns TC. A Hitchhiker's Guide Toward CSF Biomarkers for Neuro-Oncology. Neuro Oncol. 2024 Dec 30 [Epub ahead of print] View PubMed Landry AP, Wang JZ, Patil V, Gui C, Yasin M, Patel Z, Yakubov R, Kaloti R, Habibi P, Wilson M, Ajisebutu A, Ellenbogen Y, Wei Q, Singh O, Sosa J, Mansouri S, Wilson C, Cohen-Gadol AA, Virtanen P, Burket N, Blackwell M, Koenig J, Alfonso A, Davis J, Zaazoue MA, Tabatabai G, Tatagiba M, Behling F, Barnholtz-Sloan JS, Sloan AE, Chotai S, Chambless LB, Mansouri A, Ehret F, Capper D, Tsang DS, Aldape K, Gao A, Nassiri F, Zadeh G, International Consortium on Meningiomas (ICOM). Validation and next-generation update of a DNA methylation-based recurrence predictor for meningioma: a multicenter prospective study. Neuro Oncol. 2024 Nov 6 Epub 2024 Nov 06 View PubMed Sahm F, Aldape KD, Brastianos PK, Brat DJ, Dahiya S, von Deimling A, Giannini C, Gilbert MR, Louis DN, Raleigh DR, Reifenberger G, Santagata S, Sarkar C, Zadeh G, Wesseling P, Perry A. cIMPACT-NOW Update 8: Clarifications on molecular risk parameters and recommendations for WHO grading of meningiomas. Neuro Oncol. 2024 Aug 30 [Epub ahead of print] View PubMed Ci X, Chen S, Zhu R, Zarif M, Jain R, Guo W, Ramotar M, Gong L, Xu W, Singh O, Mansouri S, Zadeh G, Wei GH, Xu W, Bristow R, Berlin A, Koritzinsky M, van der Kwast T, He HH. Oral pimonidazole unveils clinicopathologic and epigenetic features of hypoxic tumour aggressiveness in localized prostate cancer. BMC Cancer. 2024 Jun 18; 24 (1):744 Epub 2024 June 18 View PubMed Voisin MR, Gui C, Patil V, Gao AF, Zadeh G. Methylation Profiling Identifies Stability of Isocitrate Dehydrogenase Mutation Over Time. Can J Neurol Sci. 2024 May; 51 (3):362-368 Epub 2023 July 12 View PubMed Nassiri F, Ajisebutu A, Patil V, Mamatjan Y, Liu J, Wang JZ, Voisin MR, Nejad R, Mansouri S, Karimi S, Chakravarthy A, Chen E, De Carvalho DD, Aldape K, Zadeh G. Metabologenomic characterization uncovers a clinically aggressive IDH mutant glioma subtype. Acta Neuropathol. 2024 Apr 7; 147 (1):68 Epub 2024 Apr 07 View PubMed Bhunia MM, Stehn CM, Jubenville TA, Novacek EL, Larsson AT, Madala M, Suppiah S, Velez-Reyes GL, Williams KB, Sokolowski M, Williams RL, Finnerty SJ, Temiz NA, Caride A, Bhagwate AV, Nagaraj NK, Lee JH, Ordog T, Zadeh G, Largaespada DA. Multiomic analyses reveal new targets of polycomb repressor complex 2 in Schwann lineage cells and malignant peripheral nerve sheath tumors. Neurooncol Adv. 2024 Jan-Dec; 6 (1):vdae188 Epub 2024 Nov 09 View PubMed Mamatjan Y, Voisin MR, Nassiri F, Moraes FY, Bunda S, So J, Salih M, Shirahata M, Ono T, Shimizu H, Schrimpf D, von Deimling A, Aldape KD, Zadeh G. Integrated molecular analysis reveals hypermethylation and overexpression of HOX genes to be poor prognosticators in isocitrate dehydrogenase mutant glioma. Neuro Oncol. 2023 Nov 2; 25 (11):2028-2041 View PubMed Zuccato JA, Patil V, Mansouri S, Voisin M, Chakravarthy A, Shen SY, Nassiri F, Mikolajewicz N, Trifoi M, Skakodub A, Zacharia B, Glantz M, De Carvalho DD, Mansouri A, Zadeh G. Cerebrospinal fluid methylome-based liquid biopsies for accurate malignant brain neoplasm classification. Neuro Oncol. 2023 Aug 3; 25 (8):1452-1460 View PubMed Lucar Figueroa E, Veilleux C, Angelov L, Brien S, Fournier-Gosselin MP, Kiss ZHT, Long M, Marcoux J, Poon K, Stiver S, Tsai E, Woodrow S, Zadeh G, Rosseau G. Canadian Women in Neurosurgery: From Early Pioneers to World Leaders. World Neurosurg. 2023 Jul; 175:78-97 Epub 2023 Apr 05 View PubMed Wang JZ, Patil V, Liu J, Dogan H, Tabatabai G, Yefet LS, Behling F, Hoffman E, Bunda S, Yakubov R, Kaloti R, Brandner S, Gao A, Cohen-Gadol A, Barnholtz-Sloan J, Skardelly M, Tatagiba M, Raleigh DR, Sahm F, Boutros PC, Aldape K, Nassiri F, Zadeh G, International Consortium on Meningiomas (ICOM). Increased mRNA expression of CDKN2A is a transcriptomic marker of clinically aggressive meningiomas. Acta Neuropathol. 2023 Jul; 146 (1):145-162 Epub 2023 Apr 24 View PubMed Wang JZ, Landry AP, Nassiri F, Merali ZA, Patel Z, Lee G, Rogers L, Zuccato JA, Voisin MR, Munoz D, Tsang DS, Laperriere N, Zadeh G. Outcomes and predictors of response to fractionated radiotherapy as primary treatment for intracranial meningiomas. Clin Transl Radiat Oncol. 2023 Jul; 41:100631 Epub 2023 Apr 24 View PubMed Wang JZ, Patil V, Liu J, Dogan H, Tabatabai G, Yefet LS, Behling F, Hoffman E, Bunda S, Yakubov R, Kaloti R, Brandner S, Gao A, Cohen-Gadol A, Barnholtz-Sloan J, Skardelly M, Tatagiba M, Raleigh DR, Sahm F, Boutros PC, Aldape K, Nassiri F, Zadeh G, International Consortium on Meningiomas (ICOM). Correction: Increased mRNA expression of CDKN2A is a transcriptomic marker of clinically aggressive meningiomas. Acta Neuropathol. 2023 Jul; 146 (1):171-172 View PubMed Maehara T, Yamazaki A, Kawabata-Iwakawa R, Fukuoka K, Akazawa A, Okura N, Nishiyama M, Nassiri F, Wang JZ, Zadeh G, Kikuta K, Oka H, Hirato J, Yokoo H, Nobusawa S. Hyperplasia of Arachnoid Trabecular Cells: A Hitherto Undescribed Lesion Observed in the Setting of Neurofibromatosis Type 1. Am J Surg Pathol. 2023 Jul 1; 47 (7):819-825 Epub 2023 May 25 View PubMed Suppiah S, Mansouri S, Mamatjan Y, Liu JC, Bhunia MM, Patil V, Rath P, Mehani B, Heir P, Bunda S, Velez-Reyes GL, Singh O, Ijad N, Pirouzmand N, Dalcourt T, Meng Y, Karimi S, Wei Q, Nassiri F, Pugh TJ, Bader GD, Aldape KD, Largaespada DA, Zadeh G. Multiplatform molecular profiling uncovers two subgroups of malignant peripheral nerve sheath tumors with distinct therapeutic vulnerabilities. Nat Commun. 2023 May 10; 14 (1):2696 View PubMed Kalyvas A, Gutierrez-Valencia E, Lau R, Ye XY, O'Halloran PJ, Mohan N, Wong C, Millar BA, Laperriere N, Conrad T, Berlin A, Bernstein M, Zadeh G, Shultz DB, Kongkham P. Anatomical and surgical characteristics correlate with pachymeningeal failure in patients with brain metastases after neurosurgical resection and adjuvant stereotactic radiosurgery. J Neurooncol. 2023 May; 163 (1):269-279 Epub 2023 May 10 View PubMed Wang JZ, Nassiri F, Aldape K, Zadeh G. Introduction: Ongoing clinical challenges in the management of meningiomas and future directions. Neurooncol Adv. 2023 May; 5 (Suppl 1):i1-i4 Epub 2023 June 03 View PubMed Samuel N, McQueen SA, Barnett RR, Everson MC, Fiala C, Lau R, Zadeh G. Parenting and Childbearing in Neurosurgical Residency: Perspectives from the United States and Canada. J Surg Educ. 2023 Apr; 80 (4):572-580 Epub 2023 Feb 01 View PubMed Rahman R, Polley MC, Alder L, Brastianos PK, Anders CK, Tawbi HA, Mehta M, Wen PY, Geyer S, de Groot J, Zadeh G, Piantadosi S, Galanis E, Khasraw M. Current drug development and trial designs in neuro-oncology: report from the first American Society of Clinical Oncology and Society for Neuro-Oncology Clinical Trials Conference. Lancet Oncol. 2023 Apr; 24 (4):e161-e171 View PubMed Mofatteh M, Mashayekhi MS, Arfaie S, Chen Y, Malhotra AK, Alvi MA, Sader N, Antonick V, Fatehi Hassanabad M, Mansouri A, Das S, Liao X, McIntyre RS, Del Maestro R, Turecki G, Cohen-Gadol AA, Zadeh G, Ashkan K. Suicidal ideation and attempts in brain tumor patients and survivors: A systematic review. Neurooncol Adv. 2023 Jan-Dec; 5 (1):vdad058 Epub 2023 May 12 View PubMed Raswoli M, Tsang DS, Zadeh G, Gao AF, Shultz DB. Malignant Mimics of Trigeminal Schwannoma. Adv Radiat Oncol. 2023 Jan-Feb; 8 (1):101056 Epub 2022 Aug 27 View PubMed O'Halloran PJ, Henry J, Amoo M, Kalyvas A, Mohan N, Zadeh G, Kalia SK, Kongkham PN. LITTing up Gliomas-Is the Future Bright? World Neurosurg X. 2023 Jan; 17:100136 Epub 2022 Sept 09 View PubMed Keshwara SM, Gillespie CS, Mustafa MA, George AM, Richardson GE, Clynch AL, Wang JZ, Lawson DDA, Gilkes CE, Farah JO, Yousaf J, Chavredakis E, Mills SJ, Brodbelt AR, Zadeh G, Millward CP, Islim AI, Jenkinson MD. Quality of life outcomes in incidental and operated meningiomas (QUALMS): a cross-sectional cohort study. J Neurooncol. 2023 Jan; 161 (2):317-327 Epub 2022 Dec 16 View PubMed Wang JZ, Nassiri F, Landry AP, Patil V, Liu J, Aldape K, Gao A, Zadeh G. The multiomic landscape of meningiomas: a review and update. J Neurooncol. 2023 Jan; 161 (2):405-414 Epub 2023 Feb 25 View PubMed Alvi MA, Elkaim LM, Levett JJ, Pando A, Roy S, Samuel N, Alotaibi NM, Zadeh G. Current landscape of social media use pertaining to glioblastoma by various stakeholders. Neurooncol Adv. 2023 Jan-Dec; 5 (1):vdad039 Epub 2023 May 24 View PubMed Wang JZ, Nassiri F, Saladino A, Zadeh G. Surgical Therapy of Non-Skull Base Meningiomas. Adv Exp Med Biol. 2023; 1416:79-94 View PubMed Wang JZ, Nassiri F, Mawrin C, Zadeh G. Genomic Landscape of Meningiomas. Adv Exp Med Biol. 2023; 1416:137-158 View PubMed Wang JZ, Agnihotri S, Zadeh G. Radiation-Induced Meningiomas. Adv Exp Med Biol. 2023; 1416:159-173 View PubMed Wang JZ, Nassiri F, Bi L, Zadeh G. Immune Profiling of Meningiomas. Adv Exp Med Biol. 2023; 1416:189-198 View PubMed Agnihotri S, Golbourn B, Huang X, Remke M, Younger S, Cairns RA, Chalil A, Smith CA, Krumholtz SL, Mackenzie D, Rakopoulos P, Ramaswamy V, Taccone MS, Mischel PS, Fuller GN, Hawkins C, Stanford W, Taylor MD, Zadeh G, Rutka JT. Correction: PINK1 Is a Negative Regulator of Growth and the Warburg Effect in Glioblastoma. Cancer Res. 2022 Dec 16; 82 (24):4695 View PubMed Fasano A, Martinez-Valbuena I, Azevedo P, da Silva CC, Algarni M, Vasilevskaya A, Anastassiadis C, Taghdiri F, Kongkham P, Radovanovic I, Zadeh G, Lang AE, Tang-Wai DF, Kovacs GG, Tartaglia MC. Alpha-Synuclein RT-QuIC in Idiopathic Normal Pressure Hydrocephalus. Ann Neurol. 2022 Dec; 92 (6):985-991 Epub 2022 Sept 28 View PubMed Gutierrez-Valencia E, Kalyvas A, Villafuerte CJ, Millar BA, Laperriere N, Conrad T, Berlin A, Weiss J, Zadeh G, Bernstein M, Kongkham P, Shultz DB. Factors correlating with survival following adjuvant or definitive radiosurgery for large brain metastases. Neuro Oncol. 2022 Nov 2; 24 (11):1925-1934 View PubMed Millesi M, Lai C, Lau R, Ye VC, Yang K, Leite M, Mohan N, Mete O, Ezzat S, Gentili F, Zadeh G, Kalyvas A. Endoscopic Treatment of Rathke's Cleft Cysts: The Case for Simple Fenestration. Brain Sci. 2022 Nov 1; 12 (11) Epub 2022 Nov 01 View PubMed Yanchus C, Drucker KL, Kollmeyer TM, Tsai R, Winick-Ng W, Liang M, Malik A, Pawling J, De Lorenzo SB, Ali A, Decker PA, Kosel ML, Panda A, Al-Zahrani KN, Jiang L, Browning JWL, Lowden C, Geuenich M, Hernandez JJ, Gosio JT, Ahmed M, Loganathan SK, Berman J, Trcka D, Michealraj KA, Fortin J, Carson B, Hollingsworth EW, Jacinto S, Mazrooei P, Zhou L, Elia A, Lupien M, He HH, Murphy DJ, Wang L, Abyzov A, Dennis JW, Maass PG, Campbell K, Wilson MD, Lachance DH, Wrensch M, Wiencke J, Mak T, Pennacchio LA, Dickel DE, Visel A, Wrana J, Taylor MD, Zadeh G, Dirks P, Eckel-Passow JE, Attisano L, Pombo A, Ida CM, Kvon EZ, Jenkins RB, Schramek D. A noncoding single-nucleotide polymorphism at 8q24 drives IDH1-mutant glioma formation. Science. 2022 Oct 7; 378 (6615):68-78 Epub 2022 Oct 06 View PubMed Yang K, Wang J, Kanwar N, Villani A, Ajani O, Fleming A, Patil V, Mamatjan Y, Wei Q, Malkin D, Shlien A, Zadeh G, Provias J. A primary DICER1-sarcoma with KRAS and TP53 mutations in a child with suspected ECCL. Brain Tumor Pathol. 2022 Oct; 39 (4):225-231 Epub 2022 June 06 View PubMed Bhanja D, Neighbors J, Connor J, Zadeh G, Mansouri A. Neuropharmacological Study of Posaconazole for Glioblastoma: A Phase 0 Clinical Trial Protocol. Neurosurgery. 2022 Oct 1; 91 (4):658-665 Epub 2022 July 25 View PubMed Voisin MR, Zuccato JA, Wang JZ, Zadeh G. Surgery for Recurrent Glioblastoma Multiforme: A Retrospective Case Control Study. World Neurosurg. 2022 Oct; 166:e624-e631 Epub 2022 July 21 View PubMed Zagzoog N, Rastgarjazi S, Ramjist J, Lui J, Hopfgartner A, Jivraj J, Yeretsian T, Zadeh G, Lin V, Yang VXD. Pilot Study of Optical Topographic Imaging Based Neuronavigation for Mastoidectomy. World Neurosurg. 2022 Oct; 166:e790-e798 Epub 2022 Aug 08 View PubMed Rajaleelan W, Chowdhury T, Moga R, Todaro C, Zadeh G, Wang J, Singh M. Perioperative Considerations in a Patient with Kleine-Levin Syndrome Undergoing a Neurosurgical Procedure under General Anesthesia. Asian J Neurosurg. 2022 Sep; 17 (3):480-484 Epub 2022 Oct 07 View PubMed Zuccato JA, Algan O, Nair VJ, Gunter T, Glenn CA, Dunn IF, Fung KM, Shultz DB, Zadeh G, Laperriere N, Tsang DS. Resection and radiotherapy for intracranial ependymoma: a multiinstitutional 50-year experience. J Neurosurg. 2022 Aug 1; 137 (2):525-532 Epub 2021 Dec 24 View PubMed Schiff D, Messersmith H, Brastianos PK, Brown PD, Burri S, Dunn IF, Gaspar LE, Gondi V, Jordan JT, Maues J, Mohile N, Redjal N, Stevens GHJ, Sulman EP, van den Bent M, Wallace HJ, Zadeh G, Vogelbaum MA. Radiation Therapy for Brain Metastases: ASCO Guideline Endorsement of ASTRO Guideline. J Clin Oncol. 2022 Jul 10; 40 (20):2271-2276 Epub 2022 May 13 View PubMed Millward CP, Armstrong TS, Barrington H, Brodbelt AR, Bulbeck H, Byrne A, Dirven L, Gamble C, Grundy PL, Islim AI, Javadpour M, Keshwara SM, Krishna ST, Mallucci CL, Marson AG, McDermott MW, Meling TR, Oliver K, Pizer B, Plaha P, Preusser M, Santarius T, Srikandarajah N, Taphoorn MJB, Watts C, Weller M, Williamson PR, Zadeh G, Zamanipoor Najafabadi AH, Jenkinson MD. Opportunities and challenges for the development of "core outcome sets" in neuro-oncology. Neuro Oncol. 2022 Jul 1; 24 (7):1048-1055 View PubMed Xie J, Zadeh G, Varn FS, Johnson KC, Martinek J, Huse JT, Nasrallah MP, Wesseling P, Cooper LAD, Malta TM, Wade TE, Sabedot TS, Brat D, Gould PV, Woehrer A, Aldape K, Ismail A, Sivajothi SK, Barthel FP, Kim H, Kocakavuk E, Ahmed N, White K, Datta I, Moon HE, Pollock S, Goldfarb C, Lee GH, Garofano L, Anderson KJ, Nehar-Belaid D, Barnholtz-Sloan JS, Bakas S, Byrne AT, D'Angelo F, Gan HK, Khasraw M, Migliozzi S, Ormond DR, Paek SH, Van Meir EG, Walenkamp AME, Watts C, Weiss T, Weller M, Palucka K, Stead LF, Poisson LM, Noushmehr H, Iavarone A, Verhaak RGW, GLASS Consortium. Glioma progression is shaped by genetic evolution and microenvironment interactions. Cell. 2022 Jun 9; 185 (12):2184-2199.e16 Epub 2022 May 31 View PubMed Galanis E, Giannini C, James D, Kaufmann TJ, Lachance D, Millward CP, Armstrong TS, Barrington H, Bell S, Brodbelt AR, Bulbeck H, Crofton A, Dirven L, Georgious T, Grundy PL, Islim AI, Javadpour M, Keshwara SM, Koszdin SD, Marson AG, McDermott MW, Meling TR, Oliver K, Plaha P, Preusser M, Santarius T, Srikandarajah N, Taphoorn MJB, Turner C, Watts C, Weller M, Williamson PR, Zadeh G, Zamanipoor Najafabadi AH, Jenkinson MD, EORTC BTG, ICOM, EANO, SNO, RANO-PRO, BNOS, SBNS, BIMS, TBTC, International Brain Tumour Alliance, Brainstrust, and Brain Tumour Foundation of Canada. Development of 'Core Outcome Sets' for Meningioma in Clinical Studies (The COSMIC Project): protocol for two systematic literature reviews, eDelphi surveys and online consensus meetings. BMJ Open. 2022 May 9; 12 (5):e057384 Epub 2022 May 09 View PubMed Sekely A, Zakzanis KK, Mabbott D, Tsang DS, Kongkham P, Zadeh G, Edelstein K. Long-term neurocognitive, psychological, and return to work outcomes in meningioma patients. Support Care Cancer. 2022 May; 30 (5):3893-3902 Epub 2022 Jan 18 View PubMed Kalyvas A, Milesi M, Leite M, Yang K, St Jacques L, Vescan A, Mete O, Ezzat S, Zadeh G, Gentili F. Endoscopic Treatment of Sellar Arachnoid Cysts via a Simple Cyst-Opening Technique: Long-Term Outcomes From a Single Center. World Neurosurg. 2022 May; 161:e625-e634 Epub 2022 Feb 23 View PubMed Sekely A, Tsang DS, Mabbott D, Kongkham P, Zadeh G, Zakzanis KK, Edelstein K. Radiation dose to circumscribed brain regions and neurocognitive function in patients with meningioma. Neurooncol Pract. 2022 May; 9 (3):208-218 Epub 2022 Feb 19 View PubMed Mirhadi S, Tam S, Li Q, Moghal N, Pham NA, Tong J, Golbourn BJ, Krieger JR, Taylor P, Li M, Weiss J, Martins-Filho SN, Raghavan V, Mamatjan Y, Khan AA, Cabanero M, Sakashita S, Huo K, Agnihotri S, Ishizawa K, Waddell TK, Zadeh G, Yasufuku K, Liu G, Shepherd FA, Moran MF, Tsao MS. Integrative analysis of non-small cell lung cancer patient-derived xenografts identifies distinct proteotypes associated with patient outcomes. Nat Commun. 2022 Apr 5; 13 (1):1811 Epub 2022 Apr 05 View PubMed Wu Z, Abdullaev Z, Pratt D, Chung HJ, Skarshaug S, Zgonc V, Perry C, Pack S, Saidkhodjaeva L, Nagaraj S, Tyagi M, Gangalapudi V, Valdez K, Turakulov R, Xi L, Raffeld M, Papanicolau-Sengos A, O'Donnell K, Newford M, Gilbert MR, Sahm F, Suwala AK, von Deimling A, Mamatjan Y, Karimi S, Nassiri F, Zadeh G, Ruppin E, Quezado M, Aldape K. Impact of the methylation classifier and ancillary methods on CNS tumor diagnostics. Neuro Oncol. 2022 Apr 1; 24 (4):571-581 View PubMed Zuccato JA, Patil V, Mansouri S, Liu JC, Nassiri F, Mamatjan Y, Chakravarthy A, Karimi S, Almeida JP, Bernat AL, Hasen M, Singh O, Khan S, Kislinger T, Sinha N, Froelich S, Adle-Biassette H, Aldape KD, De Carvalho DD, Zadeh G. DNA methylation-based prognostic subtypes of chordoma tumors in tissue and plasma. Neuro Oncol. 2022 Mar 12; 24 (3):442-454 View PubMed Yang K, Landry AP, Aljoghaiman M, Gutierrez E, Millesi M, Leite M, Kalyvas A, Jablonska PA, Vialet J, Weiss J, Millar BA, Conrad T, Laperriere N, Bernstein M, Zadeh G, Shultz D, Kongkham PN. Postoperative CT scans after resection of brain metastases: neurosurgical routine or added value? J Neurooncol. 2022 Mar; 157 (1):157-163 Epub 2022 Jan 29 View PubMed Vogelbaum MA, Brown PD, Messersmith H, Brastianos PK, Burri S, Cahill D, Dunn IF, Gaspar LE, Gatson NTN, Gondi V, Jordan JT, Lassman AB, Maues J, Mohile N, Redjal N, Stevens G, Sulman E, van den Bent M, Wallace HJ, Weinberg JS, Zadeh G, Schiff D. Treatment for Brain Metastases: ASCO-SNO-ASTRO Guideline. J Clin Oncol. 2022 Feb 10; 40 (5):492-516 Epub 2021 Dec 21 View PubMed Nieblas-Bedolla E, Zuccato J, Kluger H, Zadeh G, Brastianos PK. Central Nervous System Metastases. Hematol Oncol Clin North Am. 2022 Feb; 36 (1):161-188 Epub 2021 Oct 25 View PubMed Evans D, Goel A, Jimenez A, Nguyen M, Zhang C, Galanis E, Giannini C, Kaufmann T, Lachance D, Zadeh G, Islim AI, Millward CP, Piper RJ, Fountain DM, Mehta S, Kolamunnage-Dona R, Ali U, Koszdin SD, Georgious T, Mills SJ, Brodbelt AR, Mathew RK, Santarius T, Jenkinson MD, IMPACT Study Investigators, International Consortium on Meningioma (ICOM) and British Neurosurgical Trainee Research Collaborative (BNTRC). External validation and recalibration of an incidental meningioma prognostic model - IMPACT: protocol for an international multicentre retrospective cohort study. BMJ Open. 2022 Jan 18; 12 (1):e052705 View PubMed Germann J, Zadeh G, Mansouri A, Kucharczyk W, Lozano AM, Boutet A. Untapped Neuroimaging Tools for Neuro-Oncology: Connectomics and Spatial Transcriptomics. Cancers (Basel). 2022 Jan 18; 14 (3) View PubMed Mikolajewicz N, Khan S, Trifoi M, Skakdoub A, Ignatchenko V, Mansouri S, Zuccatto J, Zacharia BE, Glantz M, Zadeh G, Moffat J, Kislinger T, Mansouri A. Leveraging the CSF proteome toward minimally-invasive diagnostics surveillance of brain malignancies. Neurooncol Adv. 2022 Jan-Dec; 4 (1):vdac161 Epub 2022 Oct 07 View PubMed Huo M, Rose M, van Prooijen M, Cusimano MD, Laperriere N, Heaton R, Gentili F, Payne D, Shultz DB, Kongkham P, Kalia SK, Schwartz M, Bernstein M, Spears J, Zadeh G, Hodaie M, Tsang DS. Importance of Cobalt-60 Dose Rate and Biologically Effective Dose on Local Control for Intracranial Meningiomas Treated With Stereotactic Radiosurgery. Neurosurgery. 2022 Jan 1; 90 (1):140-147 View PubMed Yang K, Gutierrez-Valencia E, Landry AP, Kalyvas A, Millesi M, Leite M, Jablonska PA, Weiss J, Millar BA, Conrad T, Laperriere N, Bernstein M, Zadeh G, Shultz D, Kongkham PN. Multiplicity does not significantly affect outcomes in brain metastasis patients treated with surgery. Neurooncol Adv. 2022 Jan-Dec; 4 (1):vdac022 Epub 2022 Mar 22 View PubMed Voisin MR, Oliver K, Farrimond S, Chee T, O'Halloran P, Glas M, Zadeh G, International Brain Tumour Alliance (IBTA) Senior Advisors. Brain tumor patients and COVID-19 vaccines: results of an international survey. Neurooncol Adv. 2022 Jan-Dec; 4 (1):vdac063 Epub 2022 May 03 View PubMed Stewart J, Sahgal A, Chan AKM, Soliman H, Tseng CL, Detsky J, Myrehaug S, Atenafu EG, Helmi A, Perry J, Keith J, Jane Lim-Fat M, Munoz DG, Zadeh G, Shultz DB, Das S, Coolens C, Alcaide-Leon P, Maralani PJ. Pattern of Recurrence of Glioblastoma Versus Grade 4 IDH-Mutant Astrocytoma Following Chemoradiation: A Retrospective Matched-Cohort Analysis. Technol Cancer Res Treat. 2022 Jan-Dec; 21:15330338221109650 View PubMed Nassiri F, Liu J, Patil V, Mamatjan Y, Wang JZ, Hugh-White R, Macklin AM, Khan S, Singh O, Karimi S, Corona RI, Liu LY, Chen CY, Chakravarthy A, Wei Q, Mehani B, Suppiah S, Gao A, Workewych AM, Tabatabai G, Boutros PC, Bader GD, de Carvalho DD, Kislinger T, Aldape K, Zadeh G. A clinically applicable integrative molecular classification of meningiomas. Nature. 2021 Sep; 597 (7874):119-125 Epub 2021 Aug 25 View PubMed Galanis E, Giannini C, Kaufmann T, Lachance D, Nassiri F, Wang JZ, Singh O, Karimi S, Dalcourt T, Ijad N, Pirouzmand N, Ng HK, Saladino A, Pollo B, Dimeco F, Yip S, Gao A, Aldape KD, Zadeh G, International Consortium on Meningiomas. Loss of H3K27me3 in meningiomas. Neuro Oncol. 2021 Aug 2; 23 (8):1282-1291 View PubMed Bunda S, Zuccato JA, Voisin MR, Wang JZ, Nassiri F, Patil V, Mansouri S, Zadeh G. Liquid Biomarkers for Improved Diagnosis and Classification of CNS Tumors. Int J Mol Sci. 2021 Apr 27; 22 (9) View PubMed Wei Q, Singh O, Ekinci C, Gill J, Li M, Mamatjan Y, Karimi S, Bunda S, Mansouri S, Aldape K, Zadeh G. TNFalpha secreted by glioma associated macrophages promotes endothelial activation and resistance against anti-angiogenic therapy. Acta Neuropathol Commun. 2021 Apr 14; 9 (1):67 View PubMed Skowron P, Farooq H, Cavalli FMG, Morrissy AS, Ly M, Hendrikse LD, Wang EY, Djambazian H, Zhu H, Mungall KL, Trinh QM, Zheng T, Dai S, Stucklin ASG, Vladoiu MC, Fong V, Holgado BL, Nor C, Wu X, Abd-Rabbo D, Berube P, Wang YC, Luu B, Suarez RA, Rastan A, Gillmor AH, Lee JJY, Zhang XY, Daniels C, Dirks P, Malkin D, Bouffet E, Tabori U, Loukides J, Doz FP, Bourdeaut F, Delattre OO, Masliah-Planchon J, Ayrault O, Kim SK, Meyronet D, Grajkowska WA, Carlotti CG, de Torres C, Mora J, Eberhart CG, Van Meir EG, Kumabe T, French PJ, Kros JM, Jabado N, Lach B, Pollack IF, Hamilton RL, Rao AAN, Giannini C, Olson JM, Bognar L, Klekner A, Zitterbart K, Phillips JJ, Thompson RC, Cooper MK, Rubin JB, Liau LM, Garami M, Hauser P, Li KKW, Ng HK, Poon WS, Yancey Gillespie G, Chan JA, Jung S, McLendon RE, Thompson EM, Zagzag D, Vibhakar R, Ra YS, Garre ML, Schuller U, Shofuda T, Faria CC, Lopez-Aguilar E, Zadeh G, Hui CC, Ramaswamy V, Bailey SD, Jones SJ, Mungall AJ, Moore RA, Calarco JA, Stein LD, Bader GD, Reimand J, Ragoussis J, Weiss WA, Marra MA, Suzuki H, Taylor MD. The transcriptional landscape of Shh medulloblastoma. Nat Commun. 2021 Mar 19; 12 (1):1749 View PubMed O'Halloran PJ, Gutierrez E, Kalyvas A, Mohan N, Atallah S, Kalia S, Millar BA, Laperriere N, Conrad T, Zadeh G, Bernstein M, Shultz DB, Kongkham P. Brain Metastases: A Modern Multidisciplinary Approach. Can J Neurol Sci. 2021 Mar; 48 (2):189-197 Epub 2020 Oct 12 View PubMed Karimi S, Mansouri S, Nassiri F, Bunda S, Singh O, Brastianos PK, Dunn IF, Zadeh G. Clinical significance of checkpoint regulator "Programmed death ligand-1 (PD-L1)" expression in meningioma: review of the current status. J Neurooncol. 2021 Feb; 151 (3):443-449 Epub 2021 Feb 21 View PubMed Mansouri S, Suppiah S, Mamatjan Y, Paganini I, Liu JC, Karimi S, Patil V, Nassiri F, Singh O, Sundaravadanam Y, Rath P, Sestini R, Gensini F, Agnihotri S, Blakeley J, Ostrow K, Largaespada D, Plotkin SR, Stemmer-Rachamimov A, Ferrer MM, Pugh TJ, Aldape KD, Papi L, Zadeh G. Epigenomic, genomic, and transcriptomic landscape of schwannomatosis. Acta Neuropathol. 2021 Jan; 141 (1):101-116 Epub 2020 Oct 06 View PubMed Taslimi S, Brar K, Ellenbogen Y, Deng J, Hou W, Moraes FY, Glantz M, Zacharia BE, Tan A, Ahluwalia MS, Khasraw M, Zadeh G, Mansouri A. Comparative Efficacy of Systemic Agents for Brain Metastases From Non-Small-Cell Lung Cancer With an EGFR Mutation/ALK Rearrangement: A Systematic Review and Network Meta-Analysis. Front Oncol. 2021; 11:739765 Epub 2021 Dec 07 View PubMed Karimi S, Mansouri S, Mamatjan Y, Liu J, Nassiri F, Suppiah S, Singh O, Aldape K, Zadeh G. Programmed death ligand-1 (PD-L1) expression in meningioma; prognostic significance and its association with hypoxia and NFKB2 expression. Sci Rep. 2020 Aug 24; 10 (1):14115 View PubMed Mansouri AM, Germann J, Boutet A, Elias GJB, Mithani K, Chow CT, Karmur B, Ibrahim GM, McAndrews MP, Lozano AM, Zadeh G, Valiante TA. Identification of neural networks preferentially engaged by epileptogenic mass lesions through lesion network mapping analysis. Sci Rep. 2020 Jul 3; 10 (1):10989 Epub 2020 July 03 View PubMed Karimi S, Zuccato JA, Mamatjan Y, Mansouri S, Suppiah S, Nassiri F, Diamandis P, Munoz DG, Aldape KD, Zadeh G. The central nervous system tumor methylation classifier changes neuro-oncology practice for challenging brain tumor diagnoses and directly impacts patient care. Clin Epigenetics. 2019 Dec 5; 11 (1):185 Epub 2019 Dec 05 View PubMed Janin M, Ortiz-Barahona V, de Moura MC, Martinez-Cardus A, Llinas-Arias P, Soler M, Nachmani D, Pelletier J, Schumann U, Calleja-Cervantes ME, Moran S, Guil S, Bueno-Costa A, Pineyro D, Perez-Salvia M, Rossello-Tortella M, Pique L, Bech-Serra JJ, De La Torre C, Vidal A, Martinez-Iniesta M, Martin-Tejera JF, Villanueva A, Arias A, Cuartas I, Aransay AM, La Madrid AM, Carcaboso AM, Santa-Maria V, Mora J, Fernandez AF, Fraga MF, Aldecoa I, Pedrosa L, Graus F, Vidal N, Martinez-Soler F, Tortosa A, Carrato C, Balana C, Boudreau MW, Hergenrother PJ, Kotter P, Entian KD, Hench J, Frank S, Mansouri S, Zadeh G, Dans PD, Orozco M, Thomas G, Blanco S, Seoane J, Preiss T, Pandolfi PP, Esteller M. Epigenetic loss of RNA-methyltransferase NSUN5 in glioma targets ribosomes to drive a stress adaptive translational program. Acta Neuropathol. 2019 Dec; 138 (6):1053-1074 Epub 2019 Aug 19 View PubMed Galanis E, Giannini C, James D, Lachance D, Nassiri F, Mamatjan Y, Suppiah S, Badhiwala JH, Mansouri S, Karimi S, Saarela O, Poisson L, Gepfner-Tuma I, Schittenhelm J, Ng HK, Noushmehr H, Harter P, Baumgarten P, Weller M, Preusser M, Herold-Mende C, Tatagiba M, Tabatabai G, Sahm F, von Deimling A, Zadeh G, Aldape KD, International Consortium on Meningiomas. DNA methylation profiling to predict recurrence risk in meningioma: development and validation of a nomogram to optimize clinical management. Neuro Oncol. 2019 Jul 11; 21 (7):901-910 View PubMed Mansouri A, Hachem LD, Mansouri S, Nassiri F, Laperriere NJ, Xia D, Lindeman NI, Wen PY, Chakravarti A, Mehta MP, Hegi ME, Stupp R, Aldape KD, Zadeh G. MGMT promoter methylation status testing to guide therapy for glioblastoma: refining the approach based on emerging evidence and current challenges. Neuro Oncol. 2019 Feb 14; 21 (2):167-178 View PubMed Bunda S, Heir P, Metcalf J, Li ASC, Agnihotri S, Pusch S, Yasin M, Li M, Burrell K, Mansouri S, Singh O, Wilson M, Alamsahebpour A, Nejad R, Choi B, Kim D, von Deimling A, Zadeh G, Aldape K. CIC protein instability contributes to tumorigenesis in glioblastoma. Nat Commun. 2019 Feb 8; 10 (1):661 Epub 2019 Feb 08 View PubMed Agnihotri S, Mansouri S, Burrell K, Li M, Mamatjan Y, Liu J, Nejad R, Kumar S, Jalali S, Singh SK, Vartanian A, Chen EX, Karimi S, Singh O, Bunda S, Mansouri A, Aldape KD, Zadeh G. Ketoconazole and Posaconazole Selectively Target HK2-expressing Glioblastoma Cells. Clin Cancer Res. 2019 Jan 15; 25 (2):844-855 Epub 2018 Oct 15 View PubMed Velasquez C, Mansouri S, Mora C, Nassiri F, Suppiah S, Martino J, Zadeh G, Fernandez-Luna JL. Molecular and Clinical Insights into the Invasive Capacity of Glioblastoma Cells. J Oncol. 2019; 2019:1740763 Epub 2019 July 29 View PubMed Velasquez C, Mansouri S, Gutierrez O, Mamatjan Y, Mollinedo P, Karimi S, Singh O, Teran N, Martino J, Zadeh G, Fernandez-Luna JL. Hypoxia Can Induce Migration of Glioblastoma Cells Through a Methylation-Dependent Control of ODZ1 Gene Expression. Front Oncol. 2019; 9:1036 Epub 2019 Oct 10 View PubMed Mamatjan Y, Agnihotri S, Goldenberg A, Tonge P, Mansouri S, Zadeh G, Aldape K. Molecular Signatures for Tumor Classification: An Analysis of The Cancer Genome Atlas Data. J Mol Diagn. 2017 Nov; 19 (6):881-891 Epub 2017 Sept 01 View PubMed Agnihotri S, Suppiah S, Tonge PD, Jalali S, Danesh A, Bruce JP, Mamatjan Y, Klironomos G, Gonen L, Au K, Mansouri S, Karimi S, Sahm F, von Deimling A, Taylor MD, Laperriere NJ, Pugh TJ, Aldape KD, Zadeh G. Therapeutic radiation for childhood cancer drives structural aberrations of NF2 in meningiomas. Nat Commun. 2017 Aug 4; 8 (1):186 Epub 2017 Aug 04 View PubMed Vartanian A, Agnihotri S, Wilson MR, Burrell KE, Tonge PD, Alamsahebpour A, Jalali S, Taccone MS, Mansouri S, Golbourn B, Aldape KD, Zadeh G. Targeting hexokinase 2 enhances response to radio-chemotherapy in glioblastoma. Oncotarget. 2016 Oct 25; 7 (43):69518-69535 View PubMed Mansouri S, Singh S, Alamsahebpour A, Burrell K, Li M, Karabork M, Ekinci C, Koch E, Solaroglu I, Chang JT, Wouters B, Aldape K, Zadeh G. DICER governs characteristics of glioma stem cells and the resulting tumors in xenograft mouse models of glioblastoma. Oncotarget. 2016 Aug 30; 7 (35):56431-56446 View PubMed Mansouri A, Mansouri S, Hachem LD, Klironomos G, Vogelbaum MA, Bernstein M, Zadeh G. The role of 5-aminolevulinic acid in enhancing surgery for high-grade glioma, its current boundaries, and future perspectives: A systematic review. Cancer. 2016 Aug 15; 122 (16):2469-78 Epub 2016 May 16 View PubMed Mansouri S, Nejad R, Karabork M, Ekinci C, Solaroglu I, Aldape KD, Zadeh G. Sox2: regulation of expression and contribution to brain tumors. CNS Oncol. 2016 Jul; 5 (3):159-73 Epub 2016 May 27 View PubMed Aldape K, Zadeh G, Mansouri S, Reifenberger G, von Deimling A. Glioblastoma: pathology, molecular mechanisms and markers. Acta Neuropathol. 2015 Jun; 129 (6):829-48 Epub 2015 May 06 View PubMed Mansouri A, Badhiwala J, Mansouri S, Zadeh G. The evolving role of radiosurgery in the management of radiation-induced meningiomas: a review of current advances and future directions. Biomed Res Int. 2014; 2014:107526 Epub 2014 July 17 View PubMed PST-20574658 Inicio Publicaciones