Publicaciones Imprimir Jiang H, Nace R, Ferguson C, Zhang L, Peng KW, Russell SJ. Oncolytic cytomegaloviruses expressing EGFR-retargeted fusogenic glycoprotein complex and drug-controllable interleukin 12. Cell Rep Med. 2024 Dec 7; 101874 Epub 2024 Dec 07 View PubMed Munoz-Alia MA, Nace RA, Balakrishnan B, Zhang L, Packiriswamy N, Singh G, Warang P, Mena I, Narjari R, Vandergaast R, Peng KW, Garcia-Sastre A, Schotsaert M, Russell SJ. Surface-modified measles vaccines encoding oligomeric, prefusion-stabilized SARS-CoV-2 spike glycoproteins boost neutralizing antibody responses to Omicron and historical variants, independent of measles seropositivity. mBio. 2024 Feb 14; 15 (2):e0292823 Epub 2024 Jan 09 View PubMed Jiang H, Nace R, Ariail E, Ma Y, McGlinch E, Ferguson C, Fernandez Carrasco T, Packiriswamy N, Zhang L, Peng KW, Russell SJ. Oncolytic alpha-herpesvirus and myeloid-tropic cytomegalovirus cooperatively enhance systemic antitumor responses. Mol Ther. 2024 Jan 3; 32 (1):241-256 Epub 2023 Nov 04 View PubMed Smith KER, Peng KW, Pulido JS, Weisbrod AJ, Strand CA, Allred JB, Newsom AN, Zhang L, Packiriswamy N, Kottke T, Tonne JM, Moore M, Montane HN, Kottschade LA, McWilliams RR, Dudek AZ, Yan Y, Dimou A, Markovic SN, Federspiel MJ, Vile RG, Dronca RS, Block MS. A phase I oncolytic virus trial with vesicular stomatitis virus expressing human interferon beta and tyrosinase related protein 1 administered intratumorally and intravenously in uveal melanoma: safety, efficacy, and T cell responses. Front Immunol. 2023; 14:1279387 Epub 2023 Oct 31 View PubMed Viker KB, Steele MB, Iankov ID, Concilio SC, Ammayappan A, Bolon B, Jenks NJ, Goetz MP, Panagioti E, Federspiel MJ, Liu MC, Peng KW, Galanis E. Preclinical safety assessment of MV-s-NAP, a novel oncolytic measles virus strain armed with an H . pylori immunostimulatory bacterial transgene. Mol Ther Methods Clin Dev. 2022 Sep 8; 26:532-546 Epub 2022 July 31 View PubMed Cook J, Peng KW, Witzig TE, Broski SM, Villasboas JC, Paludo J, Patnaik M, Rajkumar V, Dispenzieri A, Leung N, Buadi F, Bennani N, Ansell SM, Zhang L, Packiriswamy N, Balakrishnan B, Brunton B, Giers M, Ginos B, Dueck AC, Geyer S, Gertz MA, Warsame R, Go RS, Hayman SR, Dingli D, Kumar S, Bergsagel L, Munoz JL, Gonsalves W, Kourelis T, Muchtar E, Kapoor P, Kyle RA, Lin Y, Siddiqui M, Fonder A, Hobbs M, Hwa L, Naik S, Russell SJ, Lacy MQ. Clinical activity of single-dose systemic oncolytic VSV virotherapy in patients with relapsed refractory T-cell lymphoma. Blood Adv. 2022 Jun 14; 6 (11):3268-3279 View PubMed Peng KW, Carey T, Lech P, Vandergaast R, Munoz-Alia MA, Packiriswamy N, Gnanadurai C, Krotova K, Tesfay M, Ziegler C, Haselton M, Sevola K, Lathrum C, Reiter S, Narjari R, Balakrishnan B, Suksanpaisan L, Sakuma T, Recker J, Zhang L, Waniger S, Russell L, Petro CD, Kyratsous CA, Baum A, Janecek JL, Lee RM, Ramachandran S, Graham ML, Russell SJ. Boosting of SARS-CoV-2 immunity in nonhuman primates using an oral rhabdoviral vaccine. Vaccine. 2022 Apr 1; 40 (15):2342-2351 Epub 2022 Jan 10 View PubMed Sakemura R, Bansal A, Siegler EL, Hefazi M, Yang N, Khadka RH, Newsom AN, Hansen MJ, Cox MJ, Manriquez Roman C, Schick KJ, Can I, Tapper EE, Nevala WK, Adada MM, Bezerra ED, Kankeu Fonkoua LA, Horvei P, Ruff MW, Parikh SA, Pandey MK, DeGrado TR, Suksanpaisan L, Kay NE, Peng KW, Russell SJ, Kenderian SS. Development of a Clinically Relevant Reporter for Chimeric Antigen Receptor T-cell Expansion, Trafficking, and Toxicity. Cancer Immunol Res. 2021 Sep; 9(9):1035-1046. Epub 2021 Jul 08. View PubMed Vandergaast R, Carey T, Reiter S, Lathrum C, Lech P, Gnanadurai C, Haselton M, Buehler J, Narjari R, Schnebeck L, Roesler A, Sevola K, Suksanpaisan L, Bexon A, Naik S, Brunton B, Weaver SC, Rafael G, Tran S, Baum A, Kyratsous CA, Peng KW, Russell SJ. IMMUNO-COV v2.0: Development and Validation of a High-Throughput Clinical Assay for Measuring SARS-CoV-2-Neutralizing Antibody Titers. mSphere. 2021 Jun 30; 6 (3):e0017021 Epub 2021 June 02 View PubMed Concilio SC, Russell SJ, Peng KW. A brief review of reporter gene imaging in oncolytic virotherapy and gene therapy. Mol Ther Oncolytics. 2021 Jun 25; 21:98-109 Epub 2021 Mar 10 View PubMed Concilio SC, Suksanpaisan L, Pham L, Peng KW, Russell SJ. Improved Noninvasive In Vivo Tracking of AAV-9 Gene Therapy Using the Perchlorate-Resistant Sodium Iodide Symporter from Minke Whale. Mol Ther. 2021 Jan 6; 29 (1):236-243 Epub 2020 Sept 30 View PubMed Cook J, Acosta-Medina AA, Peng KW, Lacy M, Russell S. Oncolytic virotherapy - Forging its place in the immunomodulatory paradigm for Multiple Myeloma. Cancer Treat Res Commun. 2021; 29:100473 Epub 2021 Oct 09 View PubMed Packiriswamy N, Upreti D, Zhou Y, Khan R, Miller A, Diaz RM, Rooney CM, Dispenzieri A, Peng KW, Russell SJ. Oncolytic measles virus therapy enhances tumor antigen-specific T-cell responses in patients with multiple myeloma. Leukemia. 2020 Dec; 34 (12):3310-3322 Epub 2020 Apr 23 View PubMed Bah ES, Nace RA, Peng KW, Munoz-Alia MA, Russell SJ. Retargeted and Stealth-Modified Oncolytic Measles Viruses for Systemic Cancer Therapy in Measles Immune Patients. Mol Cancer Ther. 2020 Oct; 19 (10):2057-2067 Epub 2020 Aug 26 View PubMed Ostrominski JW, Yada RC, Sato N, Klein M, Blinova K, Patel D, Valadez R, Palisoc M, Pittaluga S, Peng KW, San H, Lin Y, Basuli F, Zhang X, Swenson RE, Haigney M, Choyke PL, Zou J, Boehm M, Hong SG, Dunbar CE. CRISPR/Cas9-mediated introduction of the sodium/iodide symporter gene enables noninvasive in vivo tracking of induced pluripotent stem cell-derived cardiomyocytes. Stem Cells Transl Med. 2020 Oct; 9 (10):1203-1217 Epub 2020 July 23 View PubMed Nagalo BM, Breton CA, Zhou Y, Arora M, Bogenberger JM, Barro O, Steele MB, Jenks NJ, Baker AT, Duda DG, Roberts LR, Russell SJ, Peng KW, Borad MJ. Oncolytic Virus with Attributes of Vesicular Stomatitis Virus and Measles Virus in Hepatobiliary and Pancreatic Cancers. Mol Ther Oncolytics. 2020 Sep 25; 18:546-555 Epub 2020 Aug 19 View PubMed Vandergaast R, Khongwichit S, Jiang H, DeGrado TR, Peng KW, Smith DR, Russell SJ, Suksanpaisan L. Enhanced noninvasive imaging of oncology models using the NIS reporter gene and bioluminescence imaging. Cancer Gene Ther. 2020 Apr; 27 (3-4):179-188 Epub 2019 Jan 24 View PubMed Zhekova HR, Sakuma T, Johnson R, Concilio SC, Lech PJ, Zdravkovic I, Damergi M, Suksanpaisan L, Peng KW, Russell SJ, Noskov S. Mapping of Ion and Substrate Binding Sites in Human Sodium Iodide Symporter (hNIS). J Chem Inf Model. 2020 Mar 23; 60 (3):1652-1665 Epub 2020 Mar 12 View PubMed Chen VP, Chen P, Gao Y, Geng L, Steele M, Jenks N, Peng KW, Brimijoin S. Systemic Safety of a Recombinant AAV8 Vector for Human Cocaine Hydrolase Gene Therapy: A Good Laboratory Practice Preclinical Study in Mice. Hum Gene Ther. 2020 Jan; 31 (1-2):70-79 Epub 2019 Dec 19 View PubMed Zhang L, Suksanpaisan L, Jiang H, DeGrado TR, Russell SJ, Zhao M, Peng KW. Dual-Isotope SPECT Imaging with NIS Reporter Gene and Duramycin to Visualize Tumor Susceptibility to Oncolytic Virus Infection. Mol Ther Oncolytics. 2019 Dec 20; 15:178-185 Epub 2019 Oct 10 View PubMed Russell L, Peng KW, Russell SJ, Diaz RM. Oncolytic Viruses: Priming Time for Cancer Immunotherapy. BioDrugs. 2019 Oct; 33 (5):485-501 View PubMed Russell SJ, Babovic-Vuksanovic D, Bexon A, Cattaneo R, Dingli D, Dispenzieri A, Deyle DR, Federspiel MJ, Fielding A, Galanis E, Lacy MQ, Leibovich BC, Liu MC, Munoz-Alia M, Miest TC, Molina JR, Mueller S, Okuno SH, Packiriswamy N, Peikert T, Raffel C, Van Rhee F, Ungerechts G, Young PR, Zhou Y, Peng KW. Oncolytic Measles Virotherapy and Opposition to Measles Vaccination. Mayo Clin Proc. 2019 Sep; 94 (9):1834-1839 Epub 2019 June 22 View PubMed Wu X, Stenson M, Abeykoon J, Nowakowski K, Zhang L, Lawson J, Wellik L, Li Y, Krull J, Wenzl K, Novak AJ, Ansell SM, Bishop GA, Billadeau DD, Peng KW, Giles F, Schmitt DM, Witzig TE. Targeting glycogen synthase kinase 3 for therapeutic benefit in lymphoma. Blood. 2019 Jul 25; 134 (4):363-373 Epub 2019 May 17 View PubMed Merchan J, Patel MR, Powell SF, Strauss J, Cripe TP, Old MO, Diaz RM, Russell SJ, Bexon AS, Suksanpaisan L, O'Connor MK, Peng KW. Tracking VSV-IFNbeta-NIS oncolytic virus (OV) activity in patients (pts) with advanced solid tumors: The iodide symporter gene (NIS) as a pharmacodynamic (PD) marker using SPECT/CT imaging of OV therapy. Ann Oncol. 2018 Oct; 29 Suppl 8:viii479-viii480 View PubMed Powell SF, Patel MR, Merchan J, Strauss J, Cripe TP, Old MO, Diaz RM, Reckner M, Brunton B, Packiriswamy N, Upreti D, Suksanpaisan L, Vandergaast R, Khan R, Russell SJ, Peng KW, Bexon AS. VSV-IFNbeta-NIS intratumoral (IT) injection: A first-in-human (FIH), phase I study of an innovative oncolytic virotherapy, alone and with an anti-PD-L1 antibody, in patients with refractory solid tumors. Ann Oncol. 2018 Oct; 29 Suppl 8:viii439 View PubMed Suksanpaisan L, Xu R, Tesfay MZ, Bomidi C, Hamm S, Vandergaast R, Jenks N, Steele MB, Ota-Setlik A, Akhtar H, Luckay A, Nowak R, Peng KW, Eldridge JH, Clarke DK, Russell SJ, Diaz RM. Preclinical Development of Oncolytic Immunovirotherapy for Treatment of HPV(POS) Cancers. Mol Ther Oncolytics. 2018 Sep 28; 10:1-13 Epub 2018 July 05 View PubMed Brunton B, Suksanpaisan L, Li H, Liu Q, Yu Y, Vrieze A, Zhang L, Jenks N, Jiang H, DeGrado TR, Zhao C, Russell SJ, Peng KW. New transgenic NIS reporter rats for longitudinal tracking of fibrogenesis by high-resolution imaging. Sci Rep. 2018 Sep 21; 8 (1):14209 Epub 2018 Sept 21 View PubMed Russell L, Peng KW. The emerging role of oncolytic virus therapy against cancer. Chin Clin Oncol. 2018 Apr; 7 (2):16 View PubMed Naik S, Galyon GD, Jenks NJ, Steele MB, Miller AC, Allstadt SD, Suksanpaisan L, Peng KW, Federspiel MJ, Russell SJ, LeBlanc AK. Comparative Oncology Evaluation of Intravenous Recombinant Oncolytic Vesicular Stomatitis Virus Therapy in Spontaneous Canine Cancer. Mol Cancer Ther. 2018 Jan; 17 (1):316-326 Epub 2017 Nov 20 View PubMed Jiang H, Bansal A, Goyal R, Peng KW, Russell SJ, DeGrado TR. Synthesis and evaluation of (18)F-hexafluorophosphate as a novel PET probe for imaging of sodium/iodide symporter in a murine C6-glioma tumor model. Bioorg Med Chem. 2018 Jan 1; 26 (1):225-231 Epub 2017 Nov 23 View PubMed Msaouel P, Opyrchal M, Dispenzieri A, Peng KW, Federspiel MJ, Russell SJ, Galanis E. Clinical Trials with Oncolytic Measles Virus: Current Status and Future Prospects. Curr Cancer Drug Targets. 2018; 18 (2):177-187 View PubMed Dispenzieri A, Tong C, LaPlant B, Lacy MQ, Laumann K, Dingli D, Zhou Y, Federspiel MJ, Gertz MA, Hayman S, Buadi F, O'Connor M, Lowe VJ, Peng KW, Russell SJ. Phase I trial of systemic administration of Edmonston strain of measles virus genetically engineered to express the sodium iodide symporter in patients with recurrent or refractory multiple myeloma. Leukemia. 2017 Dec; 31 (12):2791-2798 Epub 2017 Apr 25 View PubMed Jiang H, Schmit NR, Koenen AR, Bansal A, Pandey MK, Glynn RB, Kemp BJ, Delaney KL, Dispenzieri A, Bakkum-Gamez JN, Peng KW, Russell SJ, Gunderson TM, Lowe VJ, DeGrado TR. Safety, pharmacokinetics, metabolism and radiation dosimetry of (18)F-tetrafluoroborate ((18)F-TFB) in healthy human subjects. EJNMMI Res. 2017 Oct 27; 7 (1):90 View PubMed Velazquez-Salinas L, Naik S, Pauszek SJ, Peng KW, Russell SJ, Rodriguez LL. Oncolytic Recombinant Vesicular Stomatitis Virus (VSV) Is Nonpathogenic and Nontransmissible in Pigs, a Natural Host of VSV. Hum Gene Ther Clin Dev. 2017 Jun; 28 (2):108-115 View PubMed Russell SJ, Peng KW. Oncolytic Virotherapy: A Contest between Apples and Oranges. Mol Ther. 2017 May 3; 25 (5):1107-1116 Epub 2017 Apr 06 View PubMed Maroun J, Munoz-Alia M, Ammayappan A, Schulze A, Peng KW, Russell S. Designing and building oncolytic viruses. Future Virol. 2017 Apr; 12 (4):193-213 Epub 2017 Mar 31 View PubMed Kleinlutzum D, Hanauer JDS, Muik A, Hanschmann KM, Kays SK, Ayala-Breton C, Peng KW, Muhlebach MD, Abel T, Buchholz CJ. Enhancing the Oncolytic Activity of CD133-Targeted Measles Virus: Receptor Extension or Chimerism with Vesicular Stomatitis Virus Are Most Effective. Front Oncol. 2017; 7:127 Epub 2017 June 26 View PubMed Lal S, Peng KW, Steele MB, Jenks N, Ma H, Kohanbash G, Phillips JJ, Raffel C. Safety Study: Intraventricular Injection of a Modified Oncolytic Measles Virus into Measles-Immune, hCD46-Transgenic, IFNalphaRko Mice. Hum Gene Ther Clin Dev. 2016 Dec; 27 (4):145-151 Epub 2016 Sept 07 View PubMed Zhang L, Steele MB, Jenks N, Grell J, Behrens M, Nace R, Naik S, Federspiel MJ, Russell SJ, Peng KW. Robust Oncolytic Virotherapy Induces Tumor Lysis Syndrome and Associated Toxicities in the MPC-11 Plasmacytoma Model. Mol Ther. 2016 Dec; 24 (12):2109-2117 Epub 2016 Sept 26 View PubMed Jiang H, Bansal A, Pandey MK, Peng KW, Suksanpaisan L, Russell SJ, DeGrado TR. Synthesis of 18F-Tetrafluoroborate via Radiofluorination of Boron Trifluoride and Evaluation in a Murine C6-Glioma Tumor Model. J Nucl Med. 2016 Sep; 57 (9):1454-9 Epub 2016 Apr 21 View PubMed Zhang L, Steele MB, Jenks N, Grell J, Suksanpaisan L, Naik S, Federspiel MJ, Lacy MQ, Russell SJ, Peng KW. Safety Studies in Tumor and Non-Tumor-Bearing Mice in Support of Clinical Trials Using Oncolytic VSV-IFNbeta-NIS. Hum Gene Ther Clin Dev. 2016 Sep; 27 (3):111-22 View PubMed Hickey RD, Mao SA, Glorioso J, Elgilani F, Amiot B, Chen H, Rinaldo P, Marler R, Jiang H, DeGrado TR, Suksanpaisan L, O'Connor MK, Freeman BL, Ibrahim SH, Peng KW, Harding CO, Ho CS, Grompe M, Ikeda Y, Lillegard JB, Russell SJ, Nyberg SL. Curative ex vivo liver-directed gene therapy in a pig model of hereditary tyrosinemia type 1. Sci Transl Med. 2016 Jul 27; 8 (349):349ra99 View PubMed Shen W, Patnaik MM, Ruiz A, Russell SJ, Peng KW. Immunovirotherapy with vesicular stomatitis virus and PD-L1 blockade enhances therapeutic outcome in murine acute myeloid leukemia. Blood. 2016 Mar 17; 127 (11):1449-58 Epub 2015 Dec 28 View PubMed Miller A, Nace R, Ayala-Breton C C, Steele M, Bailey K, Peng KW, Russell SJ. Perfusion Pressure Is a Critical Determinant of the Intratumoral Extravasation of Oncolytic Viruses. Mol Ther. 2016 Feb; 24 (2):306-317 Epub 2015 Dec 09 View PubMed Deyle DR, Escobar DZ, Peng KW, Babovic-Vuksanovic D. Oncolytic measles virus as a novel therapy for malignant peripheral nerve sheath tumors. Gene. 2015 Jul 1; 565 (1):140-5 Epub 2015 Apr 02 View PubMed Holditch SJ, Schreiber CA, Nini R, Tonne JM, Peng KW, Geurts A, Jacob HJ, Burnett JC, Cataliotti A, Ikeda Y. B-Type Natriuretic Peptide Deletion Leads to Progressive Hypertension, Associated Organ Damage, and Reduced Survival: Novel Model for Human Hypertension. Hypertension. 2015 Jul; 66 (1):199-210 Epub 2015 May 11 View PubMed Hickey RD, Mao SA, Amiot B, Suksanpaisan L, Miller A, Nace R, Glorioso J, O'Connor MK, Peng KW, Ikeda Y, Russell SJ, Nyberg SL. Noninvasive 3-dimensional imaging of liver regeneration in a mouse model of hereditary tyrosinemia type 1 using the sodium iodide symporter gene. Liver Transpl. 2015 Apr; 21 (4):442-53 Epub 2015 Mar 12 View PubMed Tesfay MZ, Ammayappan A, Federspiel MJ, Barber GN, Stojdl D, Peng KW, Russell SJ. Correction for Tesfay et al., Vesiculovirus Neutralization by Natural IgM and Complement. J Virol. 2015 Feb 1; 89(3):1945-6. View PubMed Ayala Breton C, Wikan N, Abbuhl A, Smith DR, Russell SJ, Peng KW. Oncolytic potency of HER-2 retargeted VSV-FH hybrid viruses: the role of receptor ligand affinity. Mol Ther Oncolytics. 2015; 2:15012 Epub 2015 Aug 05 View PubMed Galanis E, Atherton PJ, Maurer MJ, Knutson KL, Dowdy SC, Cliby WA, Haluska P Jr, Long HJ, Oberg A, Aderca I, Block MS, Bakkum-Gamez J, Federspiel MJ, Russell SJ, Kalli KR, Keeney G, Peng KW, Hartmann LC. Oncolytic measles virus expressing the sodium iodide symporter to treat drug-resistant ovarian cancer. Cancer Res. 2015 Jan 1; 75 (1):22-30 Epub 2014 Nov 14 View PubMed Kurisetty VVS, Heiber J, Myers R, Pereira GS, Goodwin JW, Federspiel MJ, Russell SJ, Peng KW, Barber G, Merchan JR. Preclinical safety and activity of recombinant vsv-ifn-beta in an immunocompetent model of squamous cell carcinoma of the head and neck. Head Neck. 2014 Nov; 36(11):1619-27. View PubMed Ayala-Breton C, Russell LO, Russell SJ, Peng KW. Faster replication and higher expression levels of viral glycoproteins give the vesicular stomatitis virus/measles virus hybrid VSV-FH a growth advantage over measles virus. J Virol. 2014 Aug; 88 (15):8332-9 Epub 2014 May 14 View PubMed Russell SJ, Federspiel MJ, Peng KW, Tong C, Dingli D, Morice WG, Lowe V, O'Connor MK, Kyle RA, Leung N, Buadi FK, Rajkumar SV, Gertz MA, Lacy MQ, Dispenzieri A. Remission of disseminated cancer after systemic oncolytic virotherapy. Mayo Clin Proc. 2014 Jul; 89 (7):926-33 Epub 2014 May 14 View PubMed Suksanpaisan L, Russell SJ, Peng KW. High scFv-receptor affinity does not enhance the antitumor activity of HER2-retargeted measles virus. Cancer Gene Ther. 2014 Jun; 21 (6):256-60 Epub 2014 May 30 View PubMed Tesfay MZ, Ammayappan A, Federspiel MJ, Barber GN, Stojdl D, Peng KW, Russell SJ. Vesiculovirus neutralization by natural IgM and complement. J Virol. 2014 Jun; 88 (11):6148-57 Epub 2014 Mar 19 View PubMed Liu YP, Wang J, Avanzato VA, Bakkum-Gamez JN, Russell SJ, Bell JC, Peng KW. Oncolytic vaccinia virotherapy for endometrial cancer. Gynecol Oncol. 2014 Mar; 132 (3):722-9 Epub 2014 Jan 14 View PubMed Liu YP, Russell SP, Ayala-Breton C, Russell SJ, Peng KW. Ablation of nectin4 binding compromises CD46 usage by a hybrid vesicular stomatitis virus/measles virus. J Virol. 2014 Feb; 88 (4):2195-204 Epub 2013 Dec 11 View PubMed Miller A, Suksanpaisan L, Naik S, Nace R, Federspiel M, Peng KW, Russell SJ. Reporter gene imaging identifies intratumoral infection voids as a critical barrier to systemic oncolytic virus efficacy. Mol Ther Oncolytics. 2014; 1:14005 Epub 2014 Dec 10 View PubMed Liu YP, Steele MB, Suksanpaisan L, Federspiel MJ, Russell SJ, Peng KW, Bakkum-Gamez JN. Oncolytic measles and vesicular stomatitis virotherapy for endometrial cancer. Gynecol Oncol. 2014 Jan; 132 (1):194-202 Epub 2013 Nov 15 View PubMed LeBlanc AK, Naik S, Galyon GD, Jenks N, Steele M, Peng KW, Federspiel MJ, Donnell R, Russell SJ. Safety studies on intravenous administration of oncolytic recombinant vesicular stomatitis virus in purpose-bred beagle dogs. Human Gene Therapy Clinical Development. 2013 Dec; 24(4):174-81. View PubMed Ammayappan A, Peng KW, Russell SJ. Characteristics of oncolytic vesicular stomatitis virus displaying tumor-targeting ligands. J Virol. 2013 Dec; 87 (24):13543-55 Epub 2013 Oct 02 View PubMed Ong HT, Federspiel MJ, Guo CM, Ooi LL, Russell SJ, Peng KW, Hui KM. Systemically delivered measles virus-infected mesenchymal stem cells can evade host immunity to inhibit liver cancer growth. J Hepatol. 2013 Nov; 59(5):999-1006. Epub 2013 Jul 16. View PubMed Suksanpaisan L, Pham L, McIvor S, Russell SJ, Peng KW. Oral contrast enhances the resolution of in-life NIS reporter gene imaging. Cancer Gene Ther. 2013 Nov; 20 (11):638-41 Epub 2013 Sept 13 View PubMed Yarde DN, Naik S, Nace RA, Peng KW, Federspiel MJ, Russell SJ. Meningeal myeloma deposits adversely impact the therapeutic index of an oncolytic VSV. Cancer Gene Ther. 2013 Nov; 20 (11):616-21 Epub 2013 Nov 01 View PubMed Escobar-Zarate D, Liu YP, Suksanpaisan L, Russell SJ, Peng KW. Overcoming cancer cell resistance to VSV oncolysis with JAK1/2 inhibitors. Cancer Gene Ther. 2013 Oct; 20 (10):582-9 Epub 2013 Sept 13 View PubMed Ayala-Breton C, Suksanpaisan L, Mader EK, Russell SJ, Peng KW. Amalgamating oncolytic viruses to enhance their safety, consolidate their killing mechanisms, and accelerate their spread. Mol Ther. 2013 Oct; 21 (10):1930-7 Epub 2013 July 11 View PubMed Liu C, Suksanpaisan L, Chen YW, Russell SJ, Peng KW. Enhancing cytokine-induced killer cell therapy of multiple myeloma. Exp Hematol. 2013 Jun; 41(6):508-17. Epub 2013 Feb 08. View PubMed Friedrich K, Hanauer JR, Prufer S, Munch RC, Volker I, Filippis C, Jost C, Hanschmann KM, Cattaneo R, Peng KW, Pluckthun A, Buchholz CJ, Cichutek K, Muhlebach MD. DARPin-targeting of measles virus: unique bispecificity, effective oncolysis, and enhanced safety. Mol Ther. 2013 Apr; 21(4):849-59. Epub 2013 Feb 05. View PubMed Tesfay MZ, Kirk AC, Hadac EM, Griesmann GE, Federspiel MJ, Barber GN, Henry SM, Peng KW, Russell SJ. PEGylation of vesicular stomatitis virus extends virus persistence in blood circulation of passively immunized mice. J Virol. 2013 Apr; 87 (7):3752-9 Epub 2013 Jan 16 View PubMed Lam P, Khan G, Stripecke R, Hui KM, Kasahara N, Peng KW, Guinn BA. The innovative evolution of cancer gene and cellular therapies. Cancer Gene Ther. 2013 Mar; 20(3):141-9. Epub 2013 Feb 01. View PubMed Ammayappan A, Nace R, Peng KW, Russell SJ. Neuroattenuation of vesicular stomatitis virus through picornaviral internal ribosome entry sites. J Virol. 2013 Mar; 87 (6):3217-28 Epub 2013 Jan 02 View PubMed Peng KW, Myers R, Greenslade A, Mader E, Greiner S, Federspiel MJ, Dispenzieri A, Russell SJ. Using clinically approved cyclophosphamide regimens to control the humoral immune response to oncolytic viruses. Gene Ther. 2013 Mar; 20 (3):255-61 Epub 2012 Apr 05 View PubMed Mader EK, Butler G, Dowdy SC, Mariani A, Knutson KL, Federspiel MJ, Russell SJ, Galanis E, Dietz AB, Peng KW. Optimizing patient derived mesenchymal stem cells as virus carriers for a phase I clinical trial in ovarian cancer. J Transl Med. 2013 Jan 24; 11:20 View PubMed Bailey K, Kirk A, Naik S, Nace R, Steele MB, Suksanpaisan L, Li X, Federspiel MJ, Peng KW, Kirk D, Russell SJ. Mathematical model for radial expansion and conflation of intratumoral infectious centers predicts curative oncolytic virotherapy parameters. PLoS One. 2013; 8 (9):e73759 Epub 2013 Sept 11 View PubMed Liu YP, Suksanpaisan L, Steele MB, Russell SJ, Peng KW. Induction of antiviral genes by the tumor microenvironment confers resistance to virotherapy. Sci Rep. 2013; 3:2375 View PubMed Reddi HV, Madde P, McDonough SJ, Trujillo MA, Morris JC 3rd, Myers RM, Peng KW, Russell SJ, McIver B, Eberhardt NL. Preclinical efficacy of the oncolytic measles virus expressing the sodium iodide symporter in iodine non-avid anaplastic thyroid cancer: a novel therapeutic agent allowing noninvasive imaging and radioiodine therapy. Cancer Gene Ther. 2012 Sep; 19 (9):659-65 Epub 2012 July 13 View PubMed Naik S, Nace R, Federspiel MJ, Barber GN, Peng KW, Russell SJ. Curative one-shot systemic virotherapy in murine myeloma. Leukemia. 2012 Aug; 26 (8):1870-8 Epub 2012 Mar 19 View PubMed Russell SJ, Peng KW, Bell JC. Oncolytic virotherapy. Nat Biotechnol. 2012 Jul 10; 30 (7):658-70 Epub 2012 July 10 View PubMed Iankov ID, Allen C, Federspiel MJ, Myers RM, Peng KW, Ingle JN, Russell SJ, Galanis E. Expression of immunomodulatory neutrophil-activating protein of Helicobacter pylori enhances the antitumor activity of oncolytic measles virus. Mol Ther. 2012 Jun; 20 (6):1139-47 Epub 2012 Feb 14 View PubMed Ayala-Breton C, Barber GN, Russell SJ, Peng KW. Retargeting vesicular stomatitis virus using measles virus envelope glycoproteins. Hum Gene Ther. 2012 May; 23 (5):484-91 Epub 2012 Feb 07 View PubMed Liu YP, Tong C, Dispenzieri A, Federspiel MJ, Russell SJ, Peng KW. Polyinosinic acid decreases sequestration and improves systemic therapy of measles virus. Cancer Gene Ther. 2012 Mar; 19 (3):202-11 Epub 2011 Nov 25 View PubMed Li H, Peng KW, Russell SJ. Oncolytic measles virus encoding thyroidal sodium iodide symporter for squamous cell cancer of the head and neck radiovirotherapy. Hum Gene Ther. 2012 Mar; 23 (3):295-301 Epub 2012 Jan 11 View PubMed Sakuma T, Tonne JM, Malcolm JA, Thatava T, Ohmine S, Peng KW, Ikeda Y. Long-term infection and vertical transmission of a gammaretrovirus in a foreign host species. PLoS One. 2012; 7 (1):e29682 Epub 2012 Jan 03 View PubMed Cataliotti A, Tonne JM, Bellavia D, Martin FL, Oehler EA, Harders GE, Campbell JM, Peng KW, Russell SJ, Malatino LS, Burnett JC Jr, Ikeda Y. Long-term cardiac pro-B-type natriuretic peptide gene delivery prevents the development of hypertensive heart disease in spontaneously hypertensive rats. Circulation. 2011 Mar 29; 123 (12):1297-305 Epub 2011 Mar 14 View PubMed Sakuma T, Tonne JM, Squillace KA, Ohmine S, Thatava T, Peng KW, Barry MA, Ikeda Y. Early events in retrovirus XMRV infection of the wild-derived mouse Mus pahari. J Virol. 2011 Feb; 85 (3):1205-13 Epub 2010 Nov 17 View PubMed Ennis MK, Hu C, Naik SK, Hallak LK, Peng KW, Russell SJ, Dingli D. Mutations in the stalk region of the measles virus hemagglutinin inhibit syncytium formation but not virus entry. J Virol. 2010 Oct; 84 (20):10913-7 Epub 2010 Aug 11 View PubMed Li H, Peng KW, Dingli D, Kratzke RA, Russell SJ. Oncolytic measles viruses encoding interferon beta and the thyroidal sodium iodide symporter gene for mesothelioma virotherapy. Cancer Gene Ther. 2010 Aug; 17 (8):550-8 Epub 2010 Apr 09 View PubMed Liu C, Russell SJ, Peng KW. Systemic therapy of disseminated myeloma in passively immunized mice using measles virus-infected cell carriers. Mol Ther. 2010 Jun; 18(6):1155-64. Epub 2010 Mar 16. View PubMed Jenks N, Myers R, Greiner SM, Thompson J, Mader EK, Greenslade A, Griesmann GE, Federspiel MJ, Rakela J, Borad MJ, Vile RG, Barber GN, Meier TR, Blanco MC, Carlson SK, Russell SJ, Peng KW. Safety studies on intrahepatic or intratumoral injection of oncolytic vesicular stomatitis virus expressing interferon-beta in rodents and nonhuman primates. Hum Gene Ther. 2010 Apr; 21 (4):451-62 View PubMed Galanis E, Hartmann LC, Cliby WA, Long HJ, Peethambaram PP, Barrette BA, Kaur JS, Haluska PJ Jr, Aderca I, Zollman PJ, Sloan JA, Keeney G, Atherton PJ, Podratz KC, Dowdy SC, Stanhope CR, Wilson TO, Federspiel MJ, Peng KW, Russell SJ. Phase I trial of intraperitoneal administration of an oncolytic measles virus strain engineered to express carcinoembryonic antigen for recurrent ovarian cancer. Cancer Res. 2010 Feb 1; 70 (3):875-82 Epub 2010 Jan 26 View PubMed Guinn B, Casey G, Moller MG, Kasahara N, O'Sullivan GC, Peng KW, Tangney M. International Society for Cell and Gene Therapy of Cancer 2009 Annual Meeting held in Cork, Ireland. Hum Gene Ther. 2010 Jan; 21(1):9-26. View PubMed Mader EK, Maeyama Y, Lin Y, Butler GW, Russell HM, Galanis E, Russell SJ, Dietz AB, Peng KW. Mesenchymal stem cell carriers protect oncolytic measles viruses from antibody neutralization in an orthotopic ovarian cancer therapy model. Clin Cancer Res. 2009 Dec 1; 15 (23):7246-55 Epub 2009 Nov 24 View PubMed Dingli D, Offord C, Myers R, Peng KW, Carr TW, Josic K, Russell SJ, Bajzer Z. Dynamics of multiple myeloma tumor therapy with a recombinant measles virus. Cancer Gene Ther. 2009 Dec; 16 (12):873-82 Epub 2009 June 05 View PubMed Frecha C, Costa C, Levy C, Negre D, Russell SJ, Maisner A, Salles G, Peng KW, Cosset FL, Verhoeyen E. Efficient and stable transduction of resting B lymphocytes and primary chronic lymphocyte leukemia cells using measles virus gp displaying lentiviral vectors. Blood. 2009 Oct 8; 114(15):3173-80. Epub 2009 Aug 10. View PubMed Liu C, Hasegawa K, Russell SJ, Sadelain M, Peng KW. Prostate-specific membrane antigen retargeted measles virotherapy for the treatment of prostate cancer. Prostate. 2009 Jul 01; 69(10):1128-41. View PubMed Peng KW, Dogan A, Vrana J, Liu C, Ong HT, Kumar S, Dispenzieri A, Dietz AB, Russell SJ. Tumor-associated macrophages infiltrate plasmacytomas and can serve as cell carriers for oncolytic measles virotherapy of disseminated myeloma. Am J Hematol. 2009 Jul; 84(7):401-7. View PubMed Ong HT, Trejo TR, Pham LD, Oberg AL, Russell SJ, Peng KW. Intravascularly administered RGD-displaying measles viruses bind to and infect neovessel endothelial cells in vivo. Mol Ther. 2009 Jun; 17 (6):1012-21 Epub 2009 Mar 10 View PubMed Pham L, Nakamura T, Gabriela Rosales A, Carlson SK, Bailey KR, Peng KW, Russell SJ. Concordant activity of transgene expression cassettes inserted into E1, E3 and E4 cloning sites in the adenovirus genome. J Gene Med. 2009 Mar; 11 (3):197-206 View PubMed Russell SJ, Peng KW. Measles virus for cancer therapy. Curr Top Microbiol Immunol. 2009; 330:213-41 View PubMed Wang H, Liu Y, Li Z, Tuve S, Stone D, Kalyushniy O, Shayakhmetov D, Verlinde CL, Stehle T, McVey J, Baker A, Peng KW, Roffler S, Lieber A. In vitro and in vivo properties of adenovirus vectors with increased affinity to CD46. J Virol. 2008 Nov; 82(21):10567-79. Epub 2008 Aug 27. View PubMed Han YJ, Loo SC, Phung NT, Ong HT, Russell SJ, Peng KW, Boey F, Ma J. Controlled size and morphology of EDTMP-doped hydroxyapatite nanoparticles as model for 153Samarium-EDTMP doping. J Mater Sci Mater Med. 2008 Sep; 19(9):2993-3003. Epub 2008 Mar 25. View PubMed Russell SJ, Peng KW. The utility of cells as vehicles for oncolytic virus therapies. Curr Opin Mol Ther. 2008 Aug; 10 (4):380-6 View PubMed Ong HT, Loo JSC, Boey FYC, Russell SJ, Ma J, Peng KW. Exploiting the high-affinity phosphonate-hydroxyapatite nanoparticle interaction for delivery of radiation and drugs. Journal of Nanoparticle Research. 2008 Feb; 10(1):141-50. Allen C, Paraskevakou G, Liu C, Iankov ID, Msaouel P, Zollman P, Myers R, Peng KW, Russell SJ, Galanis E. Oncolytic measles virus strains in the treatment of gliomas. Expert Opin Biol Ther. 2008 Feb; 8(2):213-20. View PubMed Chang M, Overk CR, Kastrati I, Peng KW, Yao P, Qin ZH, Petukhov P, Bolton JL, Thatcher GR. Estrogenic activity of the equine estrogen metabolite, 4-methoxyequilenin. Adv Exp Med Biol. 2008; 617:601-7. View PubMed Hasegawa K, Hu C, Nakamura T, Marks JD, Russell SJ, Peng KW. Affinity thresholds for membrane fusion triggering by viral glycoproteins. J Virol. 2007 Dec; 81 (23):13149-57 Epub 2007 Sept 05 View PubMed Myers RM, Greiner SM, Harvey ME, Griesmann G, Kuffel MJ, Buhrow SA, Reid JM, Federspiel M, Ames MM, Dingli D, Schweikart K, Welch A, Dispenzieri A, Peng KW, Russell SJ. Preclinical pharmacology and toxicology of intravenous MV-NIS, an oncolytic measles virus administered with or without cyclophosphamide. Clin Pharmacol Ther. 2007 Dec; 82(6):700-10. Epub 2007 Oct 31. View PubMed Russell SJ, Peng KW. Viruses as anticancer drugs. Trends Pharmacol Sci. 2007 Jul; 28 (7):326-33 Epub 2007 June 18 View PubMed Paraskevakou G, Allen C, Nakamura T, Zollman P, James CD, Peng KW, Schroeder M, Russell SJ, Galanis E. Epidermal growth factor receptor (EGFR)-retargeted measles virus strains effectively target EGFR- or EGFRvIII expressing gliomas. Mol Ther. 2007 Apr; 15 (4):677-86 Epub 2007 Feb 13 View PubMed Haralambieva I, Iankov I, Hasegawa K, Harvey M, Russell SJ, Peng KW. Engineering oncolytic measles virus to circumvent the intracellular innate immune response. Mol Ther. 2007 Mar; 15 (3):588-97 Epub 2007 Jan 16 View PubMed Ong HT, Hasegawa K, Dietz AB, Russell SJ, Peng KW. Evaluation of T cells as carriers for systemic measles virotherapy in the presence of antiviral antibodies. Gene Ther. 2007 Feb; 14 (4):324-33 Epub 2006 Oct 19 View PubMed Allen C, Vongpunsawad S, Nakamura T, James CD, Schroeder M, Cattaneo R, Giannini C, Krempski J, Peng KW, Goble JM, Uhm JH, Russell SJ, Galanis E. Retargeted oncolytic measles strains entering via the EGFRvIII receptor maintain significant antitumor activity against gliomas with increased tumor specificity. Cancer Res. 2006 Dec 15; 66 (24):11840-50 View PubMed Blechacz B, Splinter PL, Greiner S, Myers R, Peng KW, Federspiel MJ, Russell SJ, LaRusso NF. Engineered measles virus as a novel oncolytic viral therapy system for hepatocellular carcinoma. Hepatology. 2006 Dec; 44 (6):1465-77 View PubMed Hasegawa K, Nakamura T, Harvey M, Ikeda Y, Oberg A, Figini M, Canevari S, Hartmann LC, Peng KW. The use of a tropism-modified measles virus in folate receptor-targeted virotherapy of ovarian cancer. Clin Cancer Res. 2006 Oct 15; 12(20 Pt 1):6170-8. View PubMed Peng KW, Hadac EM, Anderson BD, Myers R, Harvey M, Greiner SM, Soeffker D, Federspiel MJ, Russell SJ. Pharmacokinetics of oncolytic measles virotherapy: eventual equilibrium between virus and tumor in an ovarian cancer xenograft model. Cancer Gene Ther. 2006 Aug; 13(8):732-8. Epub 2006 Mar 10. View PubMed Ong HT, Timm MM, Greipp PR, Witzig TE, Dispenzieri A, Russell SJ, Peng KW. Oncolytic measles virus targets high CD46 expression on multiple myeloma cells. Exp Hematol. 2006 Jun; 34 (6):713-20 View PubMed Goel A, Dispenzieri A, Geyer SM, Greiner S, Peng KW, Russell SJ. Synergistic activity of the proteasome inhibitor PS-341 with non-myeloablative 153-Sm-EDTMP skeletally targeted radiotherapy in an orthotopic model of multiple myeloma. Blood. 2006 May 15; 107 (10):4063-70 Epub 2006 Jan 19 View PubMed Hasegawa K, Pham L, O'Connor MK, Federspiel MJ, Russell SJ, Peng KW. Dual therapy of ovarian cancer using measles viruses expressing carcinoembryonic antigen and sodium iodide symporter. Clin Cancer Res. 2006 Mar 15; 12 (6):1868-75 View PubMed Hasegawa K, Peng KW. Oncolytic measles virus for ovarian cancer therapy. [Japanese]. Biotherapy. 2006; 20(6):549-56. Dingli D, Peng KW, Harvey ME, Vongpunsawad S, Bergert ER, Kyle RA, Cattaneo R, Morris JC, Russell SJ. Interaction of measles virus vectors with Auger electron emitting radioisotopes. Biochem Biophys Res Commun. 2005 Nov 11; 337 (1):22-9 View PubMed Myers R, Greiner S, Harvey M, Soeffker D, Frenzke M, Abraham K, Shaw A, Rozenblatt S, Federspiel MJ, Russell SJ, Peng KW. Oncolytic activities of approved mumps and measles vaccines for therapy of ovarian cancer. Cancer Gene Ther. 2005 Jul; 12(7):593-9. View PubMed Nakamura T, Peng KW, Harvey M, Greiner S, Lorimer IAJ, James CD, Russell SJ. Rescue and propagation of fully retargeted oncolytic measles viruses. Nat Biotechnol. 2005 Feb; 23(2):209-14. View PubMed Kanerva A, Zinn KR, Peng KW, Ranki T, Kangasniemi L, Chaudhuri TR, Desmond RA, Wang M, Takayama K, Hakkarainen T, Alfthan H, Stenman UH, Curiel DT, Hemminki A. Noninvasive dual modality in vivo monitoring of the persistence and potency of a tumor targeted conditionally replicating adenovirus. Gene Ther. 2005 Jan; 12(1):87-94. View PubMed Hadac EM, Peng KW, Nakamura T, Russell SJ. Reengineering paramyxovirus tropism. Virology. 2004 Nov 24; 329 (2):217-25 View PubMed Allen C, McDonald C, Giannini C, Peng KW, Rosales G, Russell SJ, Galanis E. Adenoviral vectors expressing fusogenic membrane glycoproteins activated via matrix metalloproteinase cleavable linkers have significant antitumor potential in the gene therapy of gliomas. J Gene Med. 2004 Nov; 6(11):1216-27. View PubMed Peng KW, Holler PD, Orr BA, Kranz DM, Russell SJ. Targeting virus entry and membrane fusion through specific peptide/MHC complexes using a high-affinity T-cell receptor. Gene Ther. 2004 Aug; 11 (15):1234-9 View PubMed Anderson BD, Nakamura T, Russell SJ, Peng KW. High CD46 receptor density determines preferential killing of tumor cells by oncolytic measles virus. Cancer Res. 2004 Jul 15; 64 (14):4919-26 View PubMed Nakamura T, Peng KW, Vongpunsawad S, Harvey M, Mizuguchi H, Hayakawa T, Cattaneo R, Russell SJ. Antibody-targeted cell fusion. Nat Biotechnol. 2004 Mar; 22 (3):331-6 Epub 2004 Feb 15 View PubMed Dingli D, Peng KW, Harvey ME, Greipp PR, O'Connor MK, Cattaneo R, Morris JC, Russell SJ. Image-guided radiovirotherapy for multiple myeloma using a recombinant measles virus expressing the thyroidal sodium iodide symporter. Blood. 2004 Mar 1; 103 (5):1641-6 Epub 2003 Nov 06 View PubMed Russell SJ, Peng KW. Primer on medical genomics. Part X: Gene therapy. Mayo Clin Proc. 2003 Nov; 78(11):1370-83. View PubMed Peng KW, Frenzke M, Myers R, Soeffker D, Harvey M, Greiner S, Galanis E, Cattaneo R, Federspiel MJ, Russell SJ. Biodistribution of oncolytic measles virus after intraperitoneal administration into Ifnar-CD46Ge transgenic mice. Hum Gene Ther. 2003 Nov 1; 14 (16):1565-77 View PubMed Ma J, Wang C, Peng KW. Electrophoretic deposition of porous hydroxyapatite scaffold. Biomaterials. 2003 Sep; 24(20):3505-10. View PubMed Ma J, Wong HF, Kong LB, Peng KW. Biomimetic processing of nanocrystallite bioactive apatite coating on titanium. Nanotechnology. 2003 Jun; 14(6):619-23. Phuong LK, Allen C, Peng KW, Giannini C, Greiner S, TenEyck CJ, Mishra PK, Macura SI, Russell SJ, Galanis EC. Use of a vaccine strain of measles virus genetically engineered to produce carcinoembryonic antigen as a novel therapeutic agent against glioblastoma multiforme. Cancer Res. 2003 May 15; 63 (10):2462-9 View PubMed Johnson KJ, Peng KW, Allen C, Russell SJ, Galanis E. Targeting the cytotoxicity of fusogenic membrane glycoproteins in gliomas through protease-substrate interaction. Gene Ther. 2003 May; 10(9):725-32. View PubMed Peng KW, Donovan KA, Schneider U, Cattaneo R, Lust JA, Russell SJ. Oncolytic measles viruses displaying a single-chain antibody against CD38, a myeloma cell marker. Blood. 2003 Apr 1; 101 (7):2557-62 Epub 2002 Nov 14 View PubMed Peng KW, TenEyck CJ, Galanis E, Kalli KR, Hartmann LC, Russell SJ. Intraperitoneal therapy of ovarian cancer using an engineered measles virus. Cancer Res. 2002 Aug 15; 62 (16):4656-62 View PubMed Peng KW, Facteau S, Wegman T, O'Kane D, Russell SJ. Non-invasive in vivo monitoring of trackable viruses expressing soluble marker peptides. Nat Med. 2002 May; 8 (5):527-31 View PubMed Larochelle A, Peng KW, Russell SJ. Lentiviral vector targeting. Curr Top Microbiol Immunol. 2002; 261:143-63 View PubMed Peng KW, Pham L, Ye H, Zufferey R, Trono D, Cosset FL, Russell SJ. Organ distribution of gene expression after intravenous infusion of targeted and untargeted lentiviral vectors. Gene Ther. 2001 Oct; 8 (19):1456-63 View PubMed Peng KW, Ahmann GJ, Pham L, Greipp PR, Cattaneo R, Russell SJ. Systemic therapy of myeloma xenografts by an attenuated measles virus. Blood. 2001 Oct 1; 98 (7):2002-7 View PubMed Pham L, Ye H, Cosset FL, Russell SJ, Peng KW. Concentration of viral vectors by co-precipitation with calcium phosphate. J Gene Med. 2001 Mar-Apr; 3(2):188-94. View PubMed Randall DJ, Wilson JM, Peng KW, Kok TW, Kuah SS, Chew SF, Lam TJ, Ip YK. The mudskipper, Periophthalmodon schlosseri, actively transports NH4+ against a concentration gradient. Am J Physiol. 1999 Dec; 277(6 Pt 2):R1562-7. View PubMed Peng KW, Russell SJ. Viral vector targeting. Curr Opin Biotechnol. 1999 Oct; 10 (5):454-7 View PubMed Peng KW. Strategies for targeting therapeutic gene delivery. Mol Med Today. 1999 Oct; 5 (10):448-53 View PubMed Peng KW, Vile R, Cosset FL, Russell S. Selective transduction of protease-rich tumors by matrix-metalloproteinase-targeted retroviral vectors. Gene Ther. 1999 Sep; 6(9):1552-7. View PubMed Peng KW, Vile R. Vector development for cancer gene therapy. Tumor Targeting. 1999 Apr; 4(1):3-11. Peng KW, Vile RG. Vector development for tumor targeting-refining the old and defining the new. Tumor Targeting. 1999; 4:1-9. Buchholz CJ, Peng KW, Morling FJ, Zhang J, Cosset FL, Russell SJ. In vivo selection of protease cleavage sites from retrovirus display libraries. Nat Biotechnol. 1998 Oct; 16(10):951-4. View PubMed Peng KW, Morling FJ, Cosset FL, Russell SJ. Retroviral gene delivery system activatable by plasmin. Tumor Targeting. 1998; 3(2):112-120. Peng KW, Chew SF, Lim CB, Kuah SSL, Kok WL, YK Ip. The mudskipper Periophthalmodon schlosseri and Boleophthalmus boddaerti can tolerate 446 M and 36 M of environmental NH3, respectively. Fish Physiol and Biochem. 1998; 19:59-69. Morling FJ, Peng KW, Cosset FL, Russell SJ. Masking of retroviral envelope functions by oligomerizing polypeptide adaptors. Virology. 1997 Jul 21; 234(1):51-61. View PubMed Peng KW, Morling FJ, Cosset FL, Murphy G, Russell SJ. A gene delivery system activatable by disease-associated matrix metalloproteinases. Hum Gene Ther. 1997 Apr 10; 8(6):729-38. View PubMed Ager S, Nilson BH, Morling FJ, Peng KW, Cosset FL, Russell SJ. Retroviral display of antibody fragments; interdomain spacing strongly influences vector infectivity. Hum Gene Ther. 1996 Nov 10; 7(17):2157-64. View PubMed Ip YK, Peng KW, Chew SF, Lim RWL, Tan GQ. Ammonia production and kinetic properties of glutamate dehydrogenase in the sipunculid Phascolosoma arcuatum exposed to anoxia. Marine Biol. 1994; 119:261-6. Chew SF, Peng KW, Low WP, Ip YK. Differences in the responses between tissues of the body wall and the internal organs of Phascolosoma arcuatum (Sipuncula) to changes in salinity. Comp Biochem Physiol. 1994; 107A(1):141-7. Peng KW, Chew SF, Ip YK. Free amino acids and cell volume regulation in the sipunculid. Phascolosoma arcuatum Physiol Zool. 1994; 67(3):580-97. Peng KW, Ip YK. Is the coelomic plasma of Phascolosoma arcuatum (Sipuncula) hyperosmotic and hypoionic in chloride to the external environment? Zool Sci. 1994; 11:879-82. Low WP, Peng KW, Phuan SK, Lee CY, Ip YK. A comparative study on the responses of the gills of 2 mudskippers to hypoxia and anoxia. J Comp Physiol B. 1993; 163:487-94. Ip YK, Chew SF, Peng KW, Lim RWL. Effects of environmental anoxia on concentrations of free amino acids and kinetic properties of glutamate dehydrogenase in three body parts of Phascolosoma arcuatum (Sipuncula). J Exp Mar Biol Ecol. 1992; 165:125-32. PST-20225641 Inicio Publicaciones