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Yi Lin, M.D., Ph.D.

  1. Hematologist
  2. Oncologist

Yi Lin, M.D., Ph.D., is a professor of medicine, she holds joint appointments in the divisions of Hematology and Experimental Pathology and Laboratory Medicine, and is the enterprise leader of cancer regenerative medicine, biotherapeutics, and biomanufacturing at Mayo Clinic. She has a BS in chemical engineering, a PhD in biomedical engineering, and an MD from Northwestern University. She completed her residency and fellowship training in internal medicine, hematology, oncology, and clinician investigator at Mayo Clinic, and is board certified in internal medicine, hematology, and medical oncology.

Dr. Lin has published more than 200 peer-reviewed articles, abstracts, and book chapters on various topics related to cancer immunotherapy, cell therapy, and regenerative medicine. She has been the principal investigator or co-investigator of several clinical trials of chimeric antigen receptor (CAR) T cell therapy, bispecific antibodies, and other novel agents for hematologic malignancies, especially multiple myeloma and lymphoma. She has also contributed to the development and validation of biomarkers, quality of life measures, and predictive models for patients undergoing cell therapy and stem cell transplantation. She has collaborated with national and international researchers, industry partners, and patient advocacy groups to advance the field of cancer immunotherapy and cell therapy.

  1. Immunotherapy
  • Cellular therapy
  • Cancer vaccine
  • Cancer immunology
  • Immunotherapy
  • Myeloid cell biology
  • Myeloma, dysproteinemia, and amyloidosis
  • Lymphoma
  1. 2011
    ResidentHematology/Oncology, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  2. 2011
    Fellow - Hematology & medical oncology fellowship, Clinical Investigator ProgramMayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  3. 2009
    ResidentClinician Investigator, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  4. 2009
    Clinician Investigator FellowDivision of Hospital Internal Medicine, Department of Internal Medicine
  5. 2007
    ResidentInternal Medicine, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  6. 2007
    Resident - Department of Internal Medicine, Mayo ClinicMayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  7. 2004
    MDNorthwestern University Feinberg School of Medicine
  8. 2000
    Ph.D. - Ph.D. Biomedical EngineeringUniversity of Minnesota
  9. 1995
    BS - Chemical EngineeringUniversity of Minnesota

Certifications

  1. 2011
    HematologyAmerican Board of Internal Medicine
  2. 2011
    Medical OncologyAmerican Board of Internal Medicine

Awards and honors

  1. 2017
    New Investigator AwardMayo Clinic Department of Medicine
  2. 2012
    NIH Loan Repayment Program, National Institutes of Health
  3. 2009
    ScholarshipPan-Pacific Lymphoma Conference
  4. 2008
    AFLAC Scholar-in-training awardAmerican Association for Cancer Research
  5. 2007
    NIH Loan Repayment Program, National Institutes of Health
  6. 2001
    J. Thomas Livermore Award for Medical Student Achievement in Hematology ResearchUniversity of Minnesota Twin Cities
  7. 2000
    Merit-based travel awardAmerican Society of Hematology
  8. 1999
    Internal Medicine Promising Young Research ScholarUniversity of Minnesota
  9. 1998
    Merit-based travel awardAmerican Society of Hematology

Professional memberships

  1. 2023 - present
    Co-Chair for Myeloma Practice Guidelines CommitteeSociety for Immunotherapy of Cancer (SITC)
  2. 2022 - present
    LeaderMayo Clinic Cancer Center
  3. 2021 - present
    Active MemberMayo Clinic Myeloma SPORE
  4. 2020 - 2021
    Search Committee memberCenter for Regenerative Medicine
  5. 2020 - present
    Committee MemberSociety for Immunotherapy of Cancer (SITC)
  6. 2020 - present
    Co-ChairCancer Cell Therapy, 2030 Novel Therapeutics Team
  7. 2020
    Co-ChairCenter for Regenerative Medicine Cellular Biomanufacturing Committee
  8. 2019 - present
    MemberCenter for International Blood and Marrow Transplant Research
  9. 2019 - present
    Co-ChairInternational Myeloma Working Group
  10. 2019 - present
    Subcommittee ChairInternational Myeloma Working Group
  11. 2018 - present
    Scientific Faculty MemberiwCAr-T
  12. 2018 - present
    Steering Committee MemberU.S. Lymphoma CAR-T Consortium
  13. 2018 - present
    Staff MemberDivision of Experimental Pathology and Laboratory Medicine, Department of Laboratory Medicine and Pathology
  14. 2017 - present
    MemberAmerican Society of Transplant and Cellular Therapy
  15. 2017 - present
    ChairCell Therapy Cross-Disciplinary Group, Mayo Clinic Cancer Center
  16. 2015 - 2018
    Subcommittee MemberInternational Society of Cellular Therapy
  17. 2014 - 2018
    Subcommittee MemberAABB
  18. 2013 - present
    Active Staff MemberAmyloidosis Interest Group, Division of Hematology and Oncology, Department of Internal Medicine
  19. 2013 - present
    Active Staff MemberAmyloidosis Interest Group, Division of Hematology and Oncology, Department of Internal Medicine
  20. 2011 - present
    ChairCell Therapy Group, Division of Hematology, Department of Internal Medicine
  21. 2011 - present
    Active Staff MemberMyeloma, Amyloidosis, Dysproteinemia Disease Oriented Group, Division of Hematology, Department of Internal Medicine
  22. 2011 - present
    Active MemberMayo Clinic Cancer Center
  23. 2011 - present
    Active Staff MemberHematology Disease Oriented Group, Division of Hematology, Department of Internal Medicine
  24. 2011 - present
    Active Staff MemberMayo Clinic Center for Regenerative Medicine
  25. 2011 - present
    Active MemberDepartment of Immunology, Mayo Graduate School of Medicine, Mayo Clinic College of Medicine and Science
  26. 2011 - present
    Active MemberImmunology and Immunotherapy
  27. 2011 - present
    Active Staff MemberUniversity of Iowa/Mayo Clinic Lymphoma SPORE
  28. 2011 - present
    Active MemberInternational Society of Cellular Therapy
  29. 2011 - present
    Active MemberSociety for Immunotherapy of Cancer
  30. 2007 - present
    Active MemberAmerican Society of Hematology
  31. 2007 - present
    Active MemberAmerican Society of Clinical Oncology
  32. 2007 - present
    Active MemberAmerican Association for Cancer Research

Publications

Research activities

See a description of research activities.