Tricuspid valve disease

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Overview

Tricuspid valve disease is a type of heart valve disease, also called valvular heart disease. The valve between the two right heart chambers, called the right atrium and the right ventricle, doesn't work as it should. The heart must work harder to pump blood to the lungs and the rest of the body.

Tricuspid valve disease often happens with other heart valve diseases.

There are different types of tricuspid valve disease. Symptoms and treatment depend on the specific valve condition. Treatment may include regular health checkups, medicines, or a procedure or surgery to fix or replace the valve.

Types

There are several types of tricuspid valve disease, including:

  • Tricuspid valve regurgitation. The tricuspid valve doesn't close properly. Blood leaks backward into the upper right heart chamber.
  • Tricuspid valve stenosis. The valve is narrowed. It's harder for blood to move between the right heart chambers.
  • Tricuspid atresia. This condition is present at birth. That means it's a congenital heart condition, also called a congenital heart defect. The tricuspid valve isn't formed. A solid sheet of tissue blocks the blood flow between the right heart chambers.
  • Ebstein anomaly. This is a rare heart condition present at birth. The tricuspid valve is in the wrong position and the valve's flaps are not formed correctly. Blood might leak backward through the valve.
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Diagnosis & treatment
Oct. 03, 2024
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  1. What are congenital heart defects? National Heart, Lung, and Blood Institute. https://www.nhlbi.nih.gov/health/congenital-heart-defects. Accessed July 17, 2024.
  2. Otto CM, et al. 2020 ACC/AHA guideline for the management of patients with valvular heart disease: A report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Journal of the American College of Cardiology. 2021; doi:10.1016/j.jacc.2020.11.018.
  3. Asmarats L, et al. Tricuspid valve disease: Diagnosis, prognosis and management of a rapidly evolving field. Nature Reviews: Cardiology. 2019; doi:10.1038/s41569-019-0186-1.
  4. Peters F, et al. Tricuspid stenosis. https://www.uptodate.com/contents/search. Accessed July 17, 2024.
  5. Connolly HM, et al. Clinical manifestations and diagnosis of Ebstein anomaly. https://www.uptodate.com/contents/search. Accessed July 17, 2024.
  6. Ebstein's anomaly. American Heart Association. https://www.heart.org/en/health-topics/congenital-heart-defects/about-congenital-heart-defects/ebsteins-anomaly. Accessed April 20, 2021.
  7. Ami TR. Allscripts EPSi. Mayo Clinic. April 23, 2024.
  8. Sumal SH, et al. Tricuspid atresia: Where are we now? Journal of Cardiac Surgery. 2020; doi:10.1111/jocs.14673.
  9. Tricuspid valve repair and tricuspid valve replacement. Mayo Clinic. https://www.mayoclinic.org/tests-procedures/tricuspid-valve-repair-tricuspid-valve-replacement/about/pac-20385087. Accessed July 17, 2024.
  10. Ferri FF. Tricuspid stenosis. In: Ferri's Clinical Advisor 2025. Elsevier; 2025. https://www.clinicalkey.com. Accessed July 16, 2024.
  11. Ferri FF. Tricuspid regurgitation. In: Ferri's Clinical Advisor 2025. Elsevier; 2025. https://www.clinicalkey.com. Accessed July 16, 2024.
  12. Problem: Tricuspid valve stenosis. American Heart Association. https://www.heart.org/en/health-topics/heart-valve-problems-and-disease/heart-valve-problems-and-causes/problem-tricuspid-valve-stenosis. Accessed July 17, 2024.
  13. Problem: Tricuspid valve regurgitation. https://www.heart.org/en/health-topics/heart-valve-problems-and-disease/heart-valve-problems-and-causes/problem-tricuspid-valve-regurgitation. American Heart Association. Accessed July 17, 2024.
  14. Tricuspid atresia. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/tricuspid-atresia/symptoms-causes/syc-20368392. Accessed July 17, 2024.
  15. Heart valve disease. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/heart-valve-disease/symptoms-causes/syc-20353727. Accessed July 17, 2024.
  16. Mankad R (expert opinion). Mayo Clinic. Aug. 12, 2024.

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