REM sleep behavior disorder

Diagnosis

To diagnose REM sleep behavior disorder, your doctor reviews your medical history and your symptoms. Your evaluation may include:

• Physical and neurological exam. Your doctor conducts a physical and neurological exam and evaluates you for REM sleep behavior disorder and other sleep disorders. REM sleep behavior disorder may have symptoms similar to other sleep disorders, or it may coexist with other sleep disorders such as obstructive sleep apnea or narcolepsy.
• Talking with your sleeping partner. Your doctor may ask your sleeping partner whether he or she has ever seen you appear to act out your dreams while sleeping, such as punching, flailing your arms in the air, shouting or screaming. Your doctor may also ask your partner to fill out a questionnaire about your sleep behaviors.
• Nocturnal sleep study (polysomnogram). Doctors may recommend an overnight study in a sleep lab. During this test, sensors monitor your heart, lung and brain activity, breathing patterns, arm and leg movements, vocalizations, and blood oxygen levels while you sleep. Typically, you'll be videotaped to document your behavior during REM sleep cycles.

Diagnostic criteria

To diagnose REM sleep behavior disorder, sleep medicine physicians typically use the symptom criteria in the International Classification of Sleep Disorders, Third Edition (ICSD-3).

For a diagnosis of REM sleep behavior disorder, criteria include the following:

• You have repeated times of arousal during sleep where you talk, make noises or perform complex motor behaviors, such as punching, kicking or running movements that often relate to the content of your dreams
• You recall dreams associated with these movements or sounds
• If you awaken during the episode, you are alert and not confused or disoriented
• A sleep study (polysomnogram) shows you have increased muscle activity during REM sleep
• Your sleep disturbance is not caused by another sleep disturbance, a mental health disorder, medication or substance abuse

REM sleep behavior disorder can be the first indication of development of a neurodegenerative disease, such as Parkinson's disease, multiple system atrophy or dementia with Lewy bodies. So if you develop REM sleep behavior disorder, it's important to follow up with your doctor.

Treatment

Treatment for REM sleep behavior disorder may include physical safeguards and medications.

Physical safeguards

Your doctor may recommend that you make changes in your sleep environment to make it safer for you and your bed partner, including:

• Padding the floor near the bed
• Removing dangerous objects from the bedroom, such as sharp items and weapons
• Placing barriers on the side of the bed
• Moving furniture and clutter away from the bed
• Protecting bedroom windows
• Possibly sleeping in a separate bed or room from your bed partner until symptoms are controlled

Medications

Examples of treatment options for REM sleep behavior disorder include:

• Melatonin. Your doctor may prescribe a dietary supplement called melatonin, which may help reduce or eliminate your symptoms. Melatonin may be as effective as clonazepam and is usually well-tolerated with few side effects.
• Clonazepam (Klonopin). This prescription medication, often used to treat anxiety, is also the traditional choice for treating REM sleep behavior disorder, appearing to effectively reduce symptoms. Clonazepam may cause side effects such as daytime sleepiness, decreased balance and worsening of sleep apnea.

Doctors continue to study several other medications that may treat REM sleep behavior disorder. Talk with your doctor to determine the most appropriate treatment option for you.

Clinical trials

Explore Mayo Clinic studies testing new treatments, interventions and tests as a means to prevent, detect, treat or manage this condition.

Preparing for your appointment

You may start out by seeing your primary care doctor. Your doctor may refer you to a sleep specialist. Consider bringing your sleeping partner, a family member or friend along, if possible. Someone who accompanies you can help you remember what the doctor says or provide additional information.

Here's some information to help you get ready for your appointment.

What you can do

Keeping a sleep diary for two weeks before your appointment can help your doctor understand what's happening. In the morning, record as much as you know of your (or your partner's) sleep issues that occurred the previous night.

Before your appointment, make a list of:

• All medications, vitamins, herbs or other supplements you're taking, as well as dosages and any recent changes
• Any symptoms you're experiencing, including any that may seem unrelated to the reason for the appointment
• Key personal information, including any major stresses or recent life changes
• Questions to ask your doctor to make the most of your time together

Some questions to ask your doctor may include:

• What's likely causing my symptoms or condition?
• What are other possible causes?
• What kinds of tests do I need?
• Is my condition likely temporary or long term?
• What's the best course of action?
• What are the alternatives to the primary approach you're suggesting?
• Should I see a specialist?
• Are there any brochures or other printed material that I can have? What websites do you recommend?

Don't hesitate to ask other questions during your appointment.

What to expect from your doctor

Your doctor is likely to ask you a number of questions. Be ready to answer them to reserve time to go over any points you want to spend more time on. Your doctor may ask:

• When did you begin experiencing symptoms?
• If you have a sleeping partner, what sleep behavior has he or she observed?
• Have you or your sleeping partner ever been injured by your sleep behaviors?
• In addition to your dream-enacting behaviors, have you ever experienced sleepwalking?
• Are you having any motor symptoms, such as handwriting problems, tremors, unsteadiness when walking or dizziness when standing up?
• Are you having any memory problems?
• Have you had sleep problems in the past?
• Does anyone else in your family have sleep problems?
• What medications are you taking?
• Do you have breathing issues during sleep, such as loud, disruptive snoring or witnessed breathing pauses?