Print DiagnosisYour healthcare professional starts with your medical history and a physical exam. The exam checks for enlarged lymph nodes in your groin and an enlarged testicle on the affected side. You also might have a rectal exam to check for prostate enlargement or tenderness. Tests might include: STI screen. If you have discharge from your urethra, your health professional puts a narrow swab into the end of your penis to get a sample of the discharge. The sample goes to a lab to be checked for gonorrhea and chlamydia. Some STI screens are done with a urine test. Urine test. A sample of your urine goes to a lab for study. The test can rule out bacterial infection. Ultrasound. This imaging test is to find the cause of testicular pain. Ultrasound with color Doppler can show if the blood flow to your testicles is lower than it should be. This could mean you have torsion. A higher than usual blood flow helps confirm the diagnosis of orchitis. More InformationUltrasoundUrinalysis TreatmentTreatment depends on the cause of orchitis. Treating bacterial orchitisAntibiotics treat bacterial orchitis and epididymo-orchitis. If the cause of the bacterial infection is an STI, your sexual partner also needs treatment. Take all the antibiotics your healthcare professional prescribes, even if your symptoms ease sooner. This is to make sure that the infection is gone. Your scrotum may be tender for several weeks or months after treatment. Rest, support the scrotum with an athletic strap, apply cold packs and take medicine to help relieve pain. Treating viral orchitisTreatment aims to ease symptoms. You might: Take nonsteroidal anti-inflammatory medicines, such as ibuprofen (Advil, Motrin IB, others) or naproxen sodium (Aleve). Be sure to talk with your healthcare professional before taking these medicines if you take blood thinners or have kidney disease. Rest in bed with your scrotum raised. Use cold packs. Most people with orchitis start to feel better in 3 to 10 days. But it can take a few weeks for the scrotum to stop being tender. Sometimes, the pain and swelling can last for several months. Request an appointment Lifestyle and home remediesTo ease discomfort: Rest in bed. Lie down so that your scrotum is raised. Put cold packs on your scrotum. Don't lift heavy objects. Preparing for your appointmentYou might be sent to a specialist in urinary issues, called a urologist. Here's some information to help you get ready for your appointment. What you can doMake a list of: Your symptoms and when they began. Your childhood illnesses and vaccines. Include recent illnesses, especially STIs or mumps. All medicines, vitamins or other supplements you take, including doses. Questions to ask your healthcare team. For orchitis, questions might include: What's the most likely cause of my symptoms? What are other possible causes? What tests do I need? What treatments are there? How long will it take before I start to feel better? Will this condition affect whether I can have children? Do I need to restrict my sexual activity? Be sure to ask all the questions you have. What to expect from your doctorYour healthcare professional is likely to ask you questions, including: How bad are your symptoms? What treatments have you tried? What, if anything, seems to ease your symptoms? What, if anything, appears to make your symptoms worse? Do you practice safer sex? How many partners do you have? Do you use a condom? By Mayo Clinic Staff Request an appointment Symptoms & causes Nov. 08, 2024 Print Show references Ferri FF. Orchitis. In: Ferri's Clinical Advisor 2024. Elsevier; 2024. https://www.clinicalkey.com. Accessed June 18. 2024. Orchitis. Merck Manual Professional Version. https://www.merckmanuals.com/professional/genitourinary-disorders/penile-and-scrotal-disorders/orchitis. Accessed June 18, 2024. Wu H, et al. Mumps orchitis: Clinical aspects and mechanisms. Frontiers in Immunology. 2021; doi:10.3389/fimmu.2021.582946. Kliegman RM, et al. Mumps. In: Nelson Textbook of Pediatrics. 22nd ed. Elsevier; 2025. https://www.clinicalkey.com. Accessed June 18, 2024. Eyre RC. Acute scrotal pain in adults. https://www.uptodate.com/contents/search. Accessed July 2, 2024. Ziegelmann MJ (expert opinion). Mayo Clinic. Accessed July 2, 2024. Related Associated Procedures Ultrasound Urinalysis Products & Services A Book: Man Overboard! A Book: Mayo Clinic Family Health Book Newsletter: Mayo Clinic Health Letter — Digital Edition Show more products and services from Mayo Clinic OrchitisSymptoms&causesDiagnosis&treatment Advertisement Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. Advertising & Sponsorship Policy Opportunities Ad Choices Mayo Clinic Press Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. 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