Overview

Ependymoma is a growth of cells that forms in the brain or spinal cord. The cells form a mass called a tumor. Ependymoma begins in the ependymal cells. These cells line the passageways that carry cerebrospinal fluid. This fluid surrounds and protects the brain and spinal cord.

There are different types of ependymomas. Some grow slowly and aren't considered cancerous. Noncancerous tumors also are called benign tumors. A benign ependymoma may grow to press on nearby tissue. Sometimes ependymomas grow more quickly and are considered cancerous. Cancerous tumors also are called malignant tumors. A malignant ependymoma may grow to invade and destroy nearby tissue. Cancerous cells can break away and spread within the brain or spinal cord.

Ependymoma can occur at any age, but most often happens in young children. Children with ependymoma may experience headaches and seizures. Ependymoma that occurs in adults is more likely to form in the spinal cord. It may cause weakness in the part of the body controlled by the nerves affected by the tumor.

Surgery is the primary treatment for ependymoma. For tumors that are growing quickly or for tumors that can't be removed completely with surgery, additional treatments may be recommended. These may include radiation therapy, radiosurgery, chemotherapy or targeted therapy.

March 22, 2025

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  1. Winn HR, ed. Ependymomas. In: Youmans and Winn Neurological Surgery. 8th ed. Elsevier; 2023. https://www.clinicalkey.com. Accessed Sept. 22, 2023.
  2. Upadhyaya SA, et al. Intracranial ependymoma and other ependymal tumors. https://www.uptodate.com/contents/search. Accessed Sept. 22, 2023.
  3. Childhood ependymoma treatment (PDQ) — Patient version. National Cancer Institute. https://www.cancer.gov/types/brain/patient/child-ependymoma-treatment-pdq. Accessed Sept. 22, 2023.
  4. Central nervous system cancers. National Comprehensive Cancer Network. https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1425. Accessed Sept. 22, 2023.

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