Surgery

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. A Study of Noninvasive Hemoglobin Monitoring in Pediatric Patients Undergoing Orthopedic Surgery

   Rochester, Minn.

   The purposes of this study are to validate noninvasive hemoglobin monitoring in postoperative orthopedic pediatric patients, to evaluate patient, parent, and provider preference of noninvasive hemoglobin monitoring compared to invasive blood draw, and to evaluate cost effectiveness of noninvasive monitoring in comparison to invasive blood draws.

2. A Study of Performing Surgery for Resectable Malignant Pleural Mesothelioma After Radiation Therapy

   Rochester, Minn.

   The purpose of this study is to assess the possibility, safety, and therapeutic effect of administering a short, quick course of high-dose radiation treatment focused on half of the chest, followed by surgery to remove that portion of the lungs, in patients with malignant pleural mesothelioma.  

3. Outcomes of Open and Endovascular Repair for Ruptured and Non-Ruptured Internal Iliac Artery Aneurysms

   Rochester, Minn.

   The purpose of this study is to evaluate different techniques to repair internal iliac artery aneurysms. Report short and long term clinical outcomes with markers of pelvic perfustion.  Compare partial pelvic perfusion preservation with bilateral complete preservation.

4. A Study of Long-term Symptom Improvement and Recurrence After Operative Management of Median Arcuate Ligament Syndrome

   Rochester, Minn.

   The purpose of this study is to evaluate long-term symptom resolution and quality of life improvements after operative management of median arcurate ligament syndrome (MALS).

5. A Study to Explore Ghrelin Levels with Primary Graft Dysfunction in Lung Transplant Recipients

   Jacksonville, Fla.

   The purpose of this study is to investigate ghrelin, a peptide that mechanistically carries the promise of therapeutics benefit for diverse aspects of morbidity associated with lung transplantation.

6. A Study to Analyze Waste Specimens from the Eye After Surgery

   Rochester, Minn.

   The purpose of this study is to learn about cell function in different tissues of the eye in various ocular diseases via transcriptomics in the Mayo Clinic laboratory.

7. A Study to Evaluate the Process of Aging in Human Atherosclerosis

   Rochester, Minn.

   The purpose of this study is to critically test the hypothesis that senescent-cell derived factors (cell aging), in particular IGFBP3, suppress the innate repair capacity of vascular smooth muscle cells (VSMC) in human atherosclerosis.

8. A Study of Mesenchymal Stem Cell (MSC) Adherence and Vessel Wall Penetration Following Intra-arterial Delivery Subsequent to Controlled Balloon Angioplasty

   Jacksonville, Fla.

   The purpose of this study is to determine the amount of MSCs that adhere to predetermined areas of arterial wall following balloon angioplasty vs no intervention, and to characterize the effect of intra-arterial injection of MSCs on predetermined areas of arterial wall via transcriptome analysis.

9. Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial

   Rochester, Minn.

   The objective of this trial is to evaluate the effectiveness of left atrial appendage exclusion (LAAE) for the prevention of ischemic stroke or systemic arterial embolism in subjects undergoing cardiac surgery who have risk factors for atrial fibrillation and ischemic stroke.

10. Breast Cancer: Can We Predict Pathological Complete Response following Neoadjuvant Treatment?

    Scottsdale/Phoenix, Ariz.

    This project will investigate whether ctDNA analysis in newly diagnosed stage I, II, III breast cancer patients treated with neoadjuvant systemic therapy can predict pathological Complete Response (pCR).