Overview

Transplant expertise

C. Burcin Taner, M.D., transplant surgeon: The bright light for a patient who's waiting for an organ transplant is that hope that the organ will be available and they will have a successful outcome. And vast majority of patients at Mayo Clinic are able to achieve that.

Julie Heimbach, M.D., transplant surgeon: What we can offer is expertise that is unrivaled. We really have been doing transplant here since the 1960s, when it comes to kidney, and from the 1980s when it comes to liver, and heart, and lung, and we have outstanding outcomes, great transplant rates, and I think we really meet the needs of the patient in an optimal way.

Bashar Aqel, M.D., transplant hepatologist: Mayo Clinic being the largest integrated transplant center in the country, if not in the world, comes from our ability to come together, combine our knowledge, combine the expertise across many specialties in order to help as many patients as possible.

Dr. Heimbach: Across our three campuses, we actually have specialty care in transplantation. We learn from each other's best practices so that we can really deliver the care that the patient needs today and tomorrow.

Dr. Taner: We have very successful clinical programs. Using that as a baseline, we developed innovation protocols, innovation programs, to really push the limits of organ transplantation. In the last several years, a new technology, what we call a machine perfusion of organs outside of the body, has become very prominent. This gives us an opportunity to assess the organ for several hours on the machine and then try to make it work for us. How do we make that organ better while we have full control of that organ on the machine?

Dr. Aqel: 13 patients die every day who are on a transplant list before they are able to reach the point of getting a transplant. With the research we have at Mayo Clinic, we're trying to reverse that, and the way to reverse that is to create new organs, what we call De Novo organs. And our research in that field targeting 3D organ printing, as well as the utilization of xenotransplantation.

Dr. Heimbach: AI has been a game changer in things like looking at biopsies. What we found is the technology can see more than the pathologist in a more accurate way, being able to detect problems earlier than we could when we were just doing it in the standard way.

Dr. Aqel: One of the most important uses of AI that we are working on now is the appropriate match of the donor and the recipient. If you add more variables from the donor, more variables from the recipient, we get as close as possible to a perfect match so that the outcome will be better than we have.

Dr. Heimbach: The unique thing about having your transplant at Mayo Clinic is, whether you live down the street or you live across the country, or even in another part of the world, we have experience in caring for you, no matter where you are.

(Gentle music continues)

Mayo Clinic's heart transplant doctors and surgeons use proven innovations to successfully treat people with congestive heart failure and other serious heart diseases. Their experience in using advanced technology, specialized procedures and an integrated approach focused on the patient makes Mayo Clinic a leader in transplant outcomes.

Experts in heart and lung surgery (cardiac and thoracic surgeons) perform nearly 180 heart transplants a year at Mayo Clinic's campuses in Arizona, Florida and Minnesota. People turn to Mayo Clinic for help with a wide range of heart diseases. And some come to Mayo Clinic Transplant Center for its expertise in multiorgan transplants and a rare condition called amyloidosis. Each year, Mayo Clinic doctors see 1,600 people with this condition, some of whom may benefit from a heart transplant.

Mayo Clinic's experts focus on your needs, bringing to your situation the strength of their:

  • Experience. Mayo Clinic's heart transplant team is recognized nationally and internationally for its expertise in comprehensive specialty treatment for people with serious heart disease. Mayo Clinic has one of the largest and most experienced practices in the United States. Doctors trained in all types of transplantation have experience treating people with complex conditions who may need multiorgan transplants, including heart-lung, heart-liver, heart-kidney and heart-lung-liver transplants.
  • Teamwork. A multidisciplinary team of doctors and health care professionals provide you with comprehensive care and the most appropriate treatment. This team may include Mayo Clinic doctors trained in transplantation, heart and lung surgery (cardiac and thoracic surgeons), heart and blood vessel diseases (cardiologists), infectious diseases, mental health conditions (psychiatrists), and other areas. Doctors trained in treating children with heart conditions (pediatric cardiologists) evaluate and treat children at Mayo Clinic's campus in Minnesota.

    An example of Mayo Clinic's unique multidisciplinary approach to teamwork occurred in 2016 when the heart transplant team at Mayo Clinic's Arizona campus successfully completed two heart transplants simultaneously. That meant two separate transplant teams were needed to procure the donor hearts, and two separate teams of surgeons and physician assistants were needed for the transplant surgeries. Both patients had been on a ventricular assist device that kept their hearts pumping until a matching heart would be available.

    The Transplant Center staff members at Mayo Clinic's campuses in Arizona, Florida and Minnesota share the same high standards and a commitment to individualized care. They work together to evaluate and treat people who may need a heart transplant. So you could be evaluated at one location and undergo surgery at another, if it's in your best interest.

  • Specialized skills. Mayo Clinic cardiologists and heart transplant surgeons advance the science and clinical practice related to many aspects of heart transplant, including multiorgan transplants and novel use of immunosuppressive (anti-rejection) drugs to improve outcomes.

    People being evaluated for serious heart conditions receive individualized care and offered all appropriate treatment options. If it's right for you, your doctor will discuss bridges to transplant or alternatives to transplant, such as medical therapy and cardiac assist devices. For example, in 2010 a patient at Mayo Clinic's campus in Arizona was the first person in the United States to go home on a total artificial heart. This helped him cope while awaiting a donor heart.

  • Innovative research. Mayo Clinic scientists and doctors are committed to expanding and sharing knowledge that makes transplants safer and improves patients' lives. And they research techniques that help people avoid transplant altogether, such as the ventricular assist device.

    At Mayo Clinic, you may have access to ongoing clinical trials and new treatments.

    Every day the Transplant Research Center brings together surgeons, cardiologists, pulmonologists, hematologists, experts in human cell therapy, and scientists from many other fields and institutions to collaborate. For example, Mayo Clinic is a leader in researching genetics and new treatments for congenital heart disease, including hypoplastic left heart syndrome. Read more about this work of the Todd and Karen Wanek Family Program for Hypoplastic Left Heart Syndrome.

Mayo Clinic surgeons perform heart transplants at Mayo Clinic's campuses in Arizona, Florida and Minnesota. Heart transplant in children is provided at Mayo Clinic's pediatric heart transplant program in Rochester, Minnesota. At Mayo Clinic's campus in Arizona, doctors trained in heart diseases (cardiologists) partner with Phoenix Children's Hospital to treat teenagers and young adults with congenital heart defects.

Services

Heart specialists discussing a patient's situation

The heart transplant care team at Mayo Clinic collaborates so that every patient gets exactly the care he or she needs.

Mayo Clinic heart doctors and surgeons work with a multidisciplinary team to ensure you get exactly the care you need. These experts treat people in many areas of heart transplantation, including those listed below. Not all services are available at each of Mayo Clinic's three campuses, in Arizona, Florida and Minnesota. Please confirm when you call for an appointment.

Surgeons of the Mayo Clinic Heart Transplant Program perform complex procedures.

Heart transplant surgeons are experts in a range of complex procedures.

Contact

Arizona

  • Mayo Clinic Heart Transplant Program
  • 5777 E. Mayo Blvd.
    Phoenix, AZ 85054
  • Phone: 800-344-6296

Florida

  • Mayo Clinic Heart Transplant Program
  • 4500 San Pablo Road
    Jacksonville, FL 32224
  • Phone: 904-956-3309

Minnesota

  • Mayo Clinic Heart Transplant Program
  • 200 First St. SW
    Rochester, MN 55905
  • Phone: 800-422-6296
July 11, 2026