Heart Transplant Program

Mayo Clinic heart transplant surgeons have performed hundreds of procedures using the most advanced technology since performing their first heart transplant more than 30 years ago. Our Transplant Center team members in Arizona, Florida and Minnesota are leaders and innovators in heart transplant, immunosuppressive (anti-rejection) medicine and cardiac assist devices that help people live better while waiting for a donor heart.

Mayo Clinic doctors and surgeons are experts in many areas of heart transplantation including:

• Multiorgan transplants
• Ventricular assist device
• Immunosuppressive medicines, such as sirolimus
• Treatment of complex heart diseases
• Amyloidosis-related heart disease
• Heart transplant for children

Mayo Clinic heart transplant outcomes compare favorably with the national average. And independent patient experience surveys indicate that a high number of Mayo Clinic patients who are being cared for by the heart transplant team are very satisfied with their care and would recommend the practice to others.

Nationally ranked

Mayo Clinic campuses are nationally recognized for expertise in cardiology and cardiovascular surgery:

Mayo Clinic in Rochester, Minnesota, Mayo Clinic in Phoenix/Scottsdale, Arizona, and Mayo Clinic in Jacksonville, Florida, are ranked among the Best Hospitals for heart and heart surgery by U.S. News & World Report. Mayo Clinic Children's Center in Rochester is ranked the No. 1 hospital in Minnesota, and the five-state region of Iowa, Minnesota, North Dakota, South Dakota and Wisconsin, according to U.S. News & World Report's 2024-2025 "Best Children's Hospitals" rankings.

Mayo Clinic is also recognized for high-quality cardiology and heart surgery subspecialty care, research, and education by a variety of national organizations:

• Top-ranked education program. The Internal Medicine Residency at Mayo Clinic College of Medicine at Mayo Clinic's campus in Minnesota is ranked among the top performing programs by U.S. News & World Report and Doximity. Heart specialists train in an internal medicine residency program before completing cardiology subspecialty training.