Clinical trials Below are current clinical trials.24 studies in Otolaryngology (ENT)/Head and Neck Surgery (open studies only). Filter this list of studies by location, status and more. Hearing Genomics Rochester, Minn. Aims, purpose, or objectives: 1) Develop hypotheses related to how the human genome and genetic variants affect hearing loss in children and adults. 2) Understand phenotypes of hearing loss on a deeper level by combining and analyzing information from audiometric, genetic, and radiologic data. 3) Explore genetic variants with an unknown significance to develop an understanding of their potential significance and explore other genes may influence an individual's hearing ability. A Study to Identify Biomarkers in the Blood, Saliva or Tissue for Oropharyngeal Squamous Cell Cancer Rochester, Minn. The purpose of this study is to identify a biomarker (or biomarkers) that is present when disease is present (i.e., at diagnosis or recurrence) and not present when disease is absent (i.e., after treatment, in HPV negative patients or in normal controls). Quality of Life in Patients with Acoustic Neuromas Rochester, Minn. Acoustic neuromas (also known as vestibular schwannomas) are benign slow growing tumors that arise from the vestibular portion of the eighth cranial nerve. Current treatment options include microsurgery, stereotactic radiosurgery and observation, using a “wait-and-scan” approach. The primary objective of this study is to compare long-term quality of life outcomes between treatments for sporadic acoustic neuromas. A Study to Evaluate Quality of Life Outcomes for Cholesteatoma Rochester, Minn. The purpose of this study is to determine the quality of life scores for patients that have undergone subtotal petrosectomy and ear canal closure for cholesteatoma and/or chronic otitis media utilizing two previously validated quality-of-life scales. Vocal Disorders Co-existing in Patients with Spasmotic Dsyphonia (SD) Jacksonville, Fla. The purpose of this study is to investigate if SD patients have vocal disorders (nodules, polyps, muscle tension dysphonia etc) more than in normal population. A Study of the Biological System of Allergic Fungal Sinusitis Mucin Jacksonville, Fla. The purpose of this study is to describe the proteome of mucus in patients without chronic rhinosinusitis (nCRS) with an emphasis on cytokines and bone morphogenic proteins present (BMPs), to describe the proteome of mucus in patients with chronic rhinosinusitis without polyps (CRSsNP) with an emphasis on cytokines and BMPs present, to describe the proteome of mucus in patients with allergic fungal sinusitis (AFRS) with an emphasis on cytokines and BMPs present, and to identify BMPs differentially elevated in patients with AFRS compared to patients with nCRS or CRS. A Study to Develop a Biorepository of Blood Samples from Cancer Patients Participating in the Gemini (IRB 19-006717) Protocol Jacksonville, Fla., Scottsdale/Phoenix, Ariz. The purpose of this study is to develop a biorepository of blood samples from cancer patients participating in the Gemini (IRB 19-006717) protocol. These samples will be used for future biomarker discovery and other translational studies. A Study to Evaluate Impedance Monitoring in Cochlear Implants Rochester, Minn. The purpose of this study is to determine changes in cochlear implant electrode impedances as a function over a period of time. A Study to Evaluate the Effect of Medical Intervention on Sinonasal Inflammation in Patients with Chronic Sinusitis, Nasal Polyps and Positive Sinus Culture Jacksonville, Fla., Scottsdale/Phoenix, Ariz. The purpose of this study is to compare change in SNOT-22 score in patients who received medication therapy such as oral antibiotics, topical antibiotics, oral corticosteroids, topical corticosteroids, leukotriene receptor antagonist, and interleukin 5 receptor antagonist following endoscopic sinus surgery versus control in patient with chronic sinusitis with nasal polyps and a positive culture. Study of Treating Patients with Vestibular Schwannoma with Aspirin Rochester, Minn. The purpose of this study is to evaluate whether the administration of aspirin can delay or slow tumor growth and maintain or improve hearing in patients with vestibular schwannoma (VS). Pagination Clinical studies PrevPrevious Page Go to page 11 Go to page 22 Go to page 33 NextNext Page Request an appointment Specialty groupsResearch July 09, 2024 Share on: FacebookTwitter Show references Otolaryngology (ENT)/Head and Neck SurgerySectionsRequest an appointmentOverviewTests & proceduresConditions treatedDoctorsDoctors by location and specialtySpecialty groupsClinical trialsResearchPatient storiesCosts & insuranceNews from Mayo ClinicReferrals Research: It's all about patients Show transcript for video Research: It's all about patients [MUSIC PLAYING] Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight. SectionsRequest an appointmentOverviewTests & proceduresConditions treatedDoctorsDoctors by location and specialtySpecialty groupsClinical trialsResearchPatient storiesCosts & insuranceNews from Mayo ClinicReferrals ORG-20424058 Medical Departments & Centers Otolaryngology (ENT)/Head and Neck Surgery