Below are current clinical trials.
Filter this list of studies by location, status and more.
Rochester, Minn.
The purpose of this study is to evaluate the effectiveness, safety, tolerability, and PK of INCB000928 over a 24-week treatment period followed by a 52-week, open-label extension period.
Rochester, Minn., Minneapolis, Minn.
The purpose of this study is to collect data about patients with chest wall and spinal deformities to develop a multicenter registry. This will speed the pace of medical advancement and treatment recommendations for these conditions.
The purpose of this study is to derive and characterize patient-specific disease models for sudden death-predisposing heritable channelopathies and cardiomyopathies using iPS-cell technology. It is hoped that the molecular, cellular, and electrophysiological phenotypes of these in-vitro disease models will further elucidate the pathophysiologic mechanisms underlying these sudden death-associated conditions.
The purpose of this study is to test the effectiveness of HappiGenius curriculum in 3rd grade students attending elementary school in the Rochester Public Schools system (Rochester, MN). Convenience samples are selected from students in classrooms receiving the HappiGenius curriculum in their normal school curriculum and students in classrooms that have opted not to have HappiGenius in their classroom this term. For the study, questionnaires will be administered at the start and conclusion of HappiGenius lessons to determine whether HappiGenius curriculum delivers the core competencies of improved attention, positive affect, self-awareness, sociality, and self-kindness.
Scottsdale/Phoenix, Ariz.
The purpose of this study is to develop the curriculum and assess its feasibility and impact on equipping young adults to better manage these aspects of survivorship: follow up medical care, work/school life, relationships and coping with the emotional impact of cancer survivorship.
The goal of this study is to determine whether significant differences exist in the prevalence of associated cardiac anomalies between right/left and right / non-coronary cusp fusion in bicuspid aortic valve.
The purpose of this study is to develop an evidenced-based guideline for pediatric opioid prescribing guideline from the emergency department for long bone fractures to more closely tailor pain management to abuse potential.
The purpose of this study is to characterize the risk of scoliosis progression based on local three-dimensional vertebral and pelvic measurements present on initial evaluation. The proposed new study aims at refining and testing the external validity of this model in a larger cohort. The next step towards using the new model in the clinical setting is to redesign the model and to externally validate the model by measuring the agreement between the new method and the traditional Cobb angle at maturity in a larger multicenter study. The ultimate goal of this research project will be to validate this new predictive model and finally transfer this new predictive tool in the hands of clinicians treating AIS.
The purposes of this study are to determine whether maternal T cells are activated and expand after in utero intervention, and to determine whether placental macrophages and histology in the maternal-fetal interface exhibit increased activation and inflammation in surgical cases born preterm (<37 weeks) compared to term.
The purpose of this study is to evaluate the continued safety and probable benefit of the MID-C system for 5 years post-implantation in Adolescent Idiopathic Scoliosis (AIS).
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