The Division of Breast and Melanoma Surgical Oncology (BMSO) at Mayo Clinic's campus in Rochester, Minnesota, centers around an experienced group of fellowship-trained surgeons who perform more than 1,200 operations annually. The BMSO team includes surgeons, nurse practitioners, nurses and support staff exclusively dedicated to the management of patients with breast and skin cancer, benign breast disease, and elevated risk of developing cancer. The team is internationally recognized for its performance of complex procedures with safe and excellent outcomes.

Mayo Clinic breast and melanoma surgeons practice in an atmosphere of inquiry and innovation, continually evolving and improving their high-volume surgical practice. The surgeons are involved in research from basic science to clinical trials to develop and evaluate novel approaches for patients with breast and skin cancer.

Integrated, multidisciplinary clinical and research practice

Care at Mayo Clinic is based on a patient-centered, collaborative approach to ensure accurate diagnosis, timely management and surgical intervention. Breast and melanoma surgeons at the Minnesota campus communicate closely with other specialists providing care to those diagnosed with cancer. Each person receiving care benefits from an individual patient-centered treatment plan that involves a multidisciplinary team of experts.

Research translates into practice innovation

In addition, surgeons within the division are also career researchers. They conduct research in basic and translational science, clinical trials for novel therapies and surgical techniques, and quality improvement to continually advance patient care.

The melanoma program shows the benefits of this approach. It leverages the latest science and care practices, relying on precise diagnosis, skilled surgical excision and the latest immunotherapies. Physician-scientists collaborate on patient care, innovative research and diagnostic excellence to provide highly individualized melanoma care, and our teams share this expertise with other medical professionals regularly.

Innovative techniques

Early and recognized experience in nipple-sparing mastectomy

Mayo Clinic surgeons were one of the earliest groups performing nipple-sparing mastectomy, and they have been doing so for more than 15 years. Combined with immediate reconstruction, it offers a woman a more natural appearance following mastectomy without diminishing cancer treatment outcomes.

Mayo surgical exploration and innovation continues: Mayo Clinic offers the latest in breast and melanoma surgical care with innovative therapies, new techniques and clinical trials.

A Study to Evaluate the da Vinci® Xi™ Surgical System in Nipple Sparing Mastectomy (NSM) Procedures

Intraoperative frozen section pathology for all breast surgeries

Mayo Clinic is one of the only medical centers in the nation to use intraoperative frozen section evaluation for all breast surgeries, which lets pathologists rapidly analyze and diagnose tissue samples while the patient is still in the operating room. This ensures that cancer is entirely removed during the procedure and minimizes the need for subsequent operations, which saves patients from added time, expense and stress.

Personalized care, rapidly tailored to your needs

Our multidisciplinary team model lets us leverage recent breast cancer treatment advances to develop a personalized comprehensive treatment plan.

For example, our approach to lymph node surgery for newly diagnosed breast cancer is to first ensure we stage the disease accurately, and based on that, provide you with the best treatment plan.

  • We assess the lymph glands under the arm using what's called an axillary ultrasound, and also possibly from a small needle biopsy. Based on what we learn there, we can adapt your course of care. When appropriate, we can further assess the involvement of any disease cells with a dual-tracer dye sentinel node biopsy.
  • The information we gain about lymph node status combined with frozen section pathology consultation lets your surgical team adapt even during the course of a procedure. This allows the team to take the right action to ensure the disease is properly addressed, but also perform no more invasive surgery than you need.
  • For patients treated with systemic therapy first, based on the response of the tumor to the therapy received prior to surgery, we tailor the surgery to the extent of remaining disease, allowing us to de-escalate treatment and minimize use of invasive procedures.

Streamlined care

Mayo Clinic understands that a diagnosis of breast cancer or melanoma is stressful for patients and families. In addition to emotional stress and uncertainty, it can be daunting to accommodate the travel, time and associated expense of obtaining care.

The Division of Breast and Melanoma Surgery Oncology is part of an integrated multidisciplinary group of cancer care specialties that provide streamlined collaboration for a comprehensive treatment plan that minimizes the time and expense of being away from home. Our surgical practice protocols are also designed to bring you detailed diagnosis and the best care as efficiently as possible. Our goal is to minimize the time between first seeking care and starting on your path to recovery.

Expedited brachytherapy treatment since 2012

For example, since 2012 Mayo Clinic has been using and refining a practice process for expedited brachytherapy treatment, for some women with low-risk, early-stage breast cancer.

  • Some patients may complete their entire treatment, including surgery and a full course of radiation, in fewer than 10 days. For certain specific profiles, the course of treatment may be even shorter, as little as five days.

Mayo Clinic's podcast on expedited breast cancer treatment options offers even more details.

Risk reduction options and care

BMSO surgeons work with internal medicine specialists dedicated to breast care and genetic counselors to help assess risk and tailor plans to mitigate risk that may involve screening, medications or surgery. Depending on the assessed level of risk, some women may want to consider risk-reducing mastectomy, or prophylactic mastectomy, often followed by reconstructive procedures.

Our multidisciplinary, high-volume practice features highly skilled breast surgeons and reconstructive plastic surgeons with special expertise in these advanced procedures. Based on a woman's individual circumstances and her preferences, our team designs the right plan for surgical risk reduction. For women interested in surgical risk reduction, our goal is to provide the greatest cancer risk reduction with the very best possible aesthetic outcomes for each woman.

A team focused on you

Having expertise concentrated in a single place, focused on you, means that you're not getting multiple differing opinions. Your care is discussed among the team, your test results are available quickly, and appointment schedules are coordinated to provide a single comprehensive plan. Highly specialized experts are working together for you.

What might take weeks or even months to accomplish elsewhere can typically be done in a matter of days at Mayo Clinic.

State-of-the-art surgical facilities

Surgery is performed at Mayo Clinic Hospital, Methodist Campus. Mayo Clinic operating rooms are equipped with the latest diagnostic and surgical equipment.

Mayo Clinic breast and melanoma surgeons have expertise in all aspects of surgical care in their specialized clinical practice.

Innovative services and special programs

  • Breast Clinic: The Breast Clinic offers diagnostic and treatment services for people who have breast changes or problems ranging from benign breast conditions to breast cancer. The Breast Clinic helps to coordinate treatment plans and then refers patients to the breast surgeons to ensure timely and comprehensive management.
  • Multidisciplinary Breast Clinic: Patients with more aggressive or advanced breast cancer are seen in the Breast Clinic and then referred to the Multidisciplinary Breast Clinic, where they meet with the breast surgical oncologist, medical oncologist and radiation oncologist on the same day to develop a comprehensive treatment plan.

Mayo Clinic breast and melanoma surgeons work closely with other specialists to diagnose and provide timely surgical intervention for complex conditions.

Mayo Clinic breast and melanoma surgeons at the Minnesota campus have experience treating a wide range of conditions, often complex or rare. You may come to Mayo Clinic on your own or through a referral from your doctor. In all cases, Mayo surgeons work with a team of doctors and subspecialists in appropriate specialties to determine the best treatment options for your specific needs. All patients with breast concerns have their initial evaluation in the Breast Clinic and then are referred to the breast surgeons.

Mayo breast and melanoma surgeons provide surgery-related management and services for the following conditions. Availability of specific services may vary between Mayo locations. Please confirm when you call to request an appointment.

Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery.

Find doctors and medical staff:

Each year on average, more than 1,000 people undergo breast cancer surgery at Mayo Clinic. This high-volume clinical practice fosters expertise among our surgeons and care teams.

Internationally recognized expertise

Mayo breast and melanoma surgeons are internationally recognized for their high-volume performance of complex procedures with excellent clinical outcomes.

Your Mayo Clinic physicians are established national leaders, widely recognized in their fields.

Outside organizations recognize Mayo Clinic breast cancer and melanoma surgeons through accreditations, grants and rankings:

  • Mayo Clinic Comprehensive Cancer Center meets the strict standards for a National Cancer Institute comprehensive cancer center, which recognizes scientific excellence and a multispecialty approach focused on cancer prevention, diagnosis and treatment.
  • Mayo Clinic is one of a select group of medical centers in the United States to be recognized as a Specialized Program of Research Excellence (SPORE) for breast cancer research, funded by the National Cancer Institute. To earn a highly competitive SPORE grant, institutions must demonstrate a high degree of collaboration between first-rate scientists and clinicians and show excellence in translational research projects.

We train surgeons: Top-ranked education program

  • The Surgery Residency program at Mayo Clinic College of Medicine at Mayo Clinic's campus in Minnesota is ranked among the top performing programs by U.S. News & World Report and Doximity.
  • Breast and melanoma surgeons serve within the medical school program, educating and training surgeons in the latest surgical approaches to care.
  • Mayo Clinic's Dedicated Breast Surgery Fellowship trains two breast surgical fellows each year.

Learn more about Mayo Clinic's quality rankings.

Translational research expertise

Breast and melanoma surgeons collaborate with scientists in Mayo Clinic's research facilities to develop new solutions for patients, rapidly leveraging research insights into surgical practice. People who come to Mayo Clinic are frequently among the first to benefit from innovative therapies, new techniques and technology, and clinical research trials. Our team is engaged in research trials for women with invasive cancer and ductal carcinoma in situ (DCIS), and also women at increased risk for future breast cancer who have atypical hyperplasia or lobular carcinoma in situ (LCIS).

Mayo Clinic in Rochester, Minnesota, Mayo Clinic in Jacksonville, Florida, and Mayo Clinic in Phoenix/Scottsdale, Arizona, are ranked among the Best Hospitals for cancer by U.S. News & World Report. Mayo Clinic in Rochester, Minnesota, is ranked as the top hospital in Minnesota, Mayo Clinic in Phoenix/Scottsdale, Arizona, is ranked as the top hospital in Arizona, and Mayo Clinic in Jacksonville, Florida, is ranked the top hospital in Florida.

Mayo Clinic advances the science and practice of breast and melanoma surgical care with innovative therapies, new techniques and clinical trials.

Read about ongoing breast surgery- and melanoma surgery-related clinical trials at Mayo Clinic.

Research is integrated into practice at Mayo Clinic, and Mayo breast surgeons and melanoma surgeons are involved in many research studies and clinical trials to discover new and improved methods of treatment.

Recent surgical research areas include:

Breast cancer

  • Ductal carcinoma in situ (DCIS) vaccine trial
  • Atypia topical tamoxifen trial
  • Cancer risks for mutations in breast cancer predisposition genes
  • Robotic nipple-sparing mastectomy for patients at increased risk of breast cancer
  • Endocrine therapy prior to surgery for invasive lobular carcinoma
  • Novel therapeutic agents in patients treated with neoadjuvant chemotherapy (ISPY2)
  • CDK4/6 inhibitors for chemotherapy resistant triple-negative breast cancer
  • Omission of axillary lymph node dissection in patients with a positive sentinel node after neoadjuvant chemotherapy (A11202)
  • Breast cancer and the microbiome

Melanoma

  • Neoadjuvant combinatorial immunotherapy for stage III melanoma
  • Markers of immune response, resistance and toxicity in melanoma
  • Prospective study of clinical-genomic tumor profiling in predicting sentinel lymph node status and risk of recurrence in early-stage melanoma
  • Melanoma diagnostics improvement through imaging interpretation
  • Minimally invasive lymph node dissection to help minimize morbidity and improve quality of life

Mayo Clinic breast surgeons together with plastic surgery and reconstructive surgeons are offering nipple areola nerve grafting for selected patients undergoing nipple-sparing mastectomy, aiming to improve sensation after the procedure.

Research labs

Explore research labs.

Research centers and programs

Publications

See a list of publications on breast-related surgical topics by Mayo Clinic authors on PubMed, a service of the National Library of Medicine.

Our patients tell us that the quality of their interactions, our attention to detail and the efficiency of their visits mean health care like they've never experienced. See the stories of satisfied Mayo Clinic patients.

Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people.

In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

Learn more about appointments at Mayo Clinic.

Please contact your insurance company to verify medical coverage and to obtain any needed authorization prior to your visit. Often, your insurer's customer service number is printed on the back of your insurance card.

Mayo Clinic in Rochester, Minnesota, Mayo Clinic in Jacksonville, Florida, and Mayo Clinic in Phoenix/Scottsdale, Arizona, are ranked among the Best Hospitals for cancer by U.S. News & World Report. Mayo Clinic in Rochester, Minnesota, is ranked as the top hospital in Minnesota, Mayo Clinic in Phoenix/Scottsdale, Arizona, is ranked as the top hospital in Arizona, and Mayo Clinic in Jacksonville, Florida, is ranked the top hospital in Florida.

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