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Adrian Vella, M.D.

  1. Endocrinologist
  2. Internist
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Publications

  1. Zeini M, Laurenti MC, Egan AM, Muthusamy K, Ramar A, Vella E, Bailey KR, Cobelli C, Dalla Man C, Vella A. The Longitudinal Effect of Diabetes-Associated Variation in TCF7L2 on Islet Function in Humans. Diabetes. 2024 Sep 1; 73 (9):1440-1446
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  2. Dugani SB, Lahr BD, Xie H, Mielke MM, Bailey KR, Vella A. County Rurality and Incidence and Prevalence of Diagnosed Diabetes in the United States. Mayo Clin Proc. 2024 Jul; 99 (7):1078-1090 Epub 2024 Mar 19
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  3. Matveyenko A, Vella A. An unclear role for the GLP-1 metabolite GLP-1(9-36) in human islet physiology. Diabetologia 2024 Jul; 67 (7):1444-1445 Epub 2024 Apr 06
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  4. Vella M, Mohan S, Christie H, Bailey KR, Cobelli C, Dalla Man C, Matveyenko A, Egan AM, Vella A. Diabetes-associated Genetic Variation in MTNR1B and Its Effect on Islet Function. J Endocr Soc. 2024 Jul 1; 8 (8):bvae130 Epub 2024 July 09
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  5. Tabatabaei Yeganeh HS, Kiliaki SA, Gnanapandithan K, Loor-Torres R, Duran M, Yousufuddin M, Prokop LJ, Vella A, Montori VM, Dugani SB. Inclusion of Rurality and Social Determinants of Health in Documents for the Primary Prevention of Type 2 Diabetes: A Systematic Review. Metab Syndr Relat Disord. 2024 Jun; 22 (5):315-326 Epub 2024 May 06
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  6. Voigt JH, Lauritsen KM, Pedersen SB, Hansen TK, Moller N, Jessen N, Laurenti MC, Dalla Man C, Vella A, Gormsen LC, Sondergaard E. Four weeks SGLT2 inhibition improves beta cell function and glucose tolerance without affecting muscle free fatty acid or glucose uptake in subjects with type 2 diabetes. Basic Clin Pharmacol Toxicol. 2024 May; 134 (5):643-656 Epub 2024 Feb 26
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  7. Pinto E Vairo F, Kemppainen JL, Vitek CRR, Whalen DA, Kolbert KJ, Sikkink KJ, Kroc SA, Kruisselbrink T, Shupe GF, Knudson AK, Burke EM, Loftus EC, Bandel LA, Prochnow CA, Mulvihill LA, Thomas B, Gable DM, Graddy CB, Garzon GGM, Ekpoh IU, Porquera EMC, Fervenza FC, Hogan MC, El Ters M, Warrington KJ, Davis JM 3rd, Koster MJ, Orandi AB, Basiaga ML, Vella A, Kumar S, Creo AL, Lteif AN, Pittock ST, Tebben PJ, Abate EG, Joshi AY, Ristagno EH, Patnaik MS, Schimmenti LA, Dhamija R, Sabrowsky SM, Wierenga KJ, Keddis MT, Samadder NJJ, Presutti RJ, Robinson SI, Stephens MC, Roberts LR, Faubion WA Jr, Driscoll SW, Wong-Kisiel LC, Selcen D, Flanagan EP, Ramanan VK, Jackson LM, Mauermann ML, Ortega VE, Anderson SA, Aoudia SL, Klee EW, McAllister TM, Lazaridis KN. Correction: Implementation of genomic medicine for rare disease in a tertiary healthcare system: Mayo Clinic Program for Rare and Undiagnosed Diseases (PRaUD). J Transl Med. 2024 Apr 30; 22 (1):400
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  8. Das D, Christie HE, Hegazi M, Takawy M, Pone KA, Vella A, Egan AM. Twin Pregnancy Complicated by Gestational Diabetes Mellitus: Maternal and Neonatal Outcomes. J Endocr Soc. 2024 Apr 6; 8 (6):bvae075 Epub 2024 Apr 16
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  9. Karakaplan ND, Song Y, Laurenti MC, Vella A, Jensen MD. Suppression of Endogenous Insulin Secretion by Euglycemic Hyperinsulinemia. J Clin Endocrinol Metab. 2024 Jan 18; 109 (2):e596-e601
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  10. Zhang L, Vella A, Nair KS, Jensen MD. Characteristics of Normal Weight Insulin-Resistant Adults with Unfavorable Health Outcomes. Metab Syndr Relat Disord. 2024 Jan 16 [Epub ahead of print]
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  11. Kahn SE, Anderson CAM, Buse JB, Selvin E, Angell SY, Aroda VR, Cheng AYY, Danne T, Echouffo-Tcheugui JB, Fitzpatrick SL, Gadgil MD, Gastaldelli A, Gloyn AL, Green JB, Jastreboff AM, Kanaya AM, Kandula NR, Kovesdy CP, Laiteerapong N, Nadeau KJ, Pettus J, Pop-Busui R, Posey JE, Powe CE, Rebholz CM, Rickels MR, Sattar N, Shaw JE, Sims EK, Utzschneider KM, Vella A, Zhang C. Reflecting on a Year at the Helm of Diabetes Care. Diabetes Care 2024 Jan 1; 47 (1):4-6
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  12. Sada A, Ramachandran D, Oberoi M, Habermann EB, Lyden ML, Dy BM, Foster TR, Halfdanarson TR, Levy MJ, Vella A, McKenzie TJ. Ethanol Ablation for Benign Insulinoma: Intraoperative and Endoscopic Approaches. J Surg Res. 2024 Jan; 293:663-669 Epub 2023 Oct 13
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  13. De Leon DD, Arnoux JB, Banerjee I, Bergada I, Bhatti T, Conwell LS, Fu J, Flanagan SE, Gillis D, Meissner T, Mohnike K, Pasquini TLS, Shah P, Stanley CA, Vella A, Yorifuji T, Thornton PS. International Guidelines for the Diagnosis and Management of Hyperinsulinism. Horm Res Paediatr. 2024; 97 (3):279-298 Epub 2023 July 14
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  14. Welch AA, Farahani RA, Egan AM, Laurenti MC, Zeini M, Vella M, Bailey KR, Cobelli C, Dalla Man C, Matveyenko A, Vella A. Glucagon-like peptide-1 receptor blockade impairs islet secretion and glucose metabolism in humans. J Clin Invest. 2023 Nov 15; 133 (22)
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  15. Faggionato E, Laurenti MC, Vella A, Dalla Man C. Nonlinear mixed effects modeling of glucagon kinetics in healthy subjects. IEEE Transactions on Biomedical Engineering. 2023 Sep; 70 (9):2733-40
  16. Schembri Wismayer D, Laurenti MC, Song Y, Egan AM, Welch AA, Bailey KR, Cobelli C, Dalla Man C, Jensen MD, Vella A. Effects of acute changes in fasting glucose and free fatty acid concentrations on indices of beta-cell function and glucose metabolism in subjects without diabetes. Am J Physiol Endocrinol Metab. 2023 Aug 1; 325 (2):E119-E131 Epub 2023 June 07
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  17. Pinto E Vairo F, Kemppainen JL, Vitek CRR, Whalen DA, Kolbert KJ, Sikkink KJ, Kroc SA, Kruisselbrink T, Shupe GF, Knudson AK, Burke EM, Loftus EC, Bandel LA, Prochnow CA, Mulvihill LA, Thomas B, Gable DM, Graddy CB, Garzon GGM, Ekpoh IU, Porquera EMC, Fervenza FC, Hogan MC, El Ters M, Warrington KJ, Davis JM 3rd, Koster MJ, Orandi AB, Basiaga ML, Vella A, Kumar S, Creo AL, Lteif AN, Pittock ST, Tebben PJ, Abate EG, Joshi AY, Ristagno EH, Patnaik MS, Schimmenti LA, Dhamija R, Sabrowsky SM, Wierenga KJ, Keddis MT, Samadder NJJ, Presutti RJ, Robinson SI, Stephens MC, Roberts LR, Faubion WA Jr, Driscoll SW, Wong-Kisiel LC, Selcen D, Flanagan EP, Ramanan VK, Jackson LM, Mauermann ML, Ortega VE, Anderson SA, Aoudia SL, Klee EW, McAllister TM, Lazaridis KN. Implementation of genomic medicine for rare disease in a tertiary healthcare system: Mayo Clinic Program for Rare and Undiagnosed Diseases (PRaUD). J Transl Med. 2023 Jun 23; 21(1):410.
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  18. Bielinski SJ, Yanes Cardozo LL, Takahashi PY, Larson NB, Castillo A, Podwika A, De Filippis E, Hernandez V, Mahajan GJ, Gonzalez C, Shubhangi Shubhangi, Decker PA, Killian JM, Olson JE, St Sauver JL, Shah P, Vella A, Ryu E, Liu H, Marshall GD, Cerhan JR, Singh D, Summers RL. Predictors of Metformin Failure: Repurposing Electronic Health Record Data to Identify High-Risk Patients. J Clin Endocrinol Metab. 2023 Jun 16; 108 (7):1740-1746
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  19. Moazzami, Venkatesan, Rajagopalan, Vella, Egan. Gestational Diabetes Mellitus (GDM)—Outcomes for Normal-Weight Individuals Diabetes. 2023.
  20. Sada A, McKenzie TJ, Vella A, Levy MJ, Halfdanarson TR. Interventional vs surgical procedures in localized/nonmetastatic insulinomas (ablation vs surgery). Endocr Relat Cancer. 2023 Jun 1; 30 (6) Epub 2023 May 02
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  21. Farahani RA, Egan AM, Welch AA, Laurenti MC, Cobelli C, Dalla Man C, Vella A. The Effect of Glucagon-Like Peptide 1 Receptor Blockade on Glucagon-Induced Stimulation of Insulin Secretion. Diabetes. 2023 Apr 1; 72 (4):449-454
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  22. Schembri Wismayer D, Laurenti MC, Song Y, Egan AM, Welch AA, Bailey KR, Cobelli C, Dalla Man C, Jensen MD, Vella A. Effects of acute changes in fasting glucose and free fatty acid concentrations on indices of beta-cell function and glucose metabolism in subjects without diabetes. American Journal of Physiology. Endocrinology and Metabolism. 2023; 325 (2):E119-31
  23. Tabatabaei Yeganeh HS, Prokop LJ, Kiliaki SA, Gnanapandithan K, Yousufuddin M, Vella A, Montori VM, Dugani SB. Guidelines, position statements, and advisories for the primary prevention of type 2 diabetes, hypertension, and cardiovascular disease in rural populations: A systematic review protocol. PLoS One. 2023; 18 (6):e0288116 Epub 2023 June 29
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  24. Kahn SE, Anderson CAM, Buse JB, Selvin E, Angell SY, Aroda VR, Castle JR, Cheng AYY, Danne T, Echouffo-Tcheugui JB, Florez JC, Gadgil MD, Gastaldelli A, Green JB, Jastreboff AM, Kanaya AM, Kandula NR, Kovesdy CP, Laiteerapong N, Nadeau KJ, Pop-Busui R, Powe CE, Rebholz CM, Rickels MR, Sattar N, Shaw JE, Sims EK, Utzschneider KM, Vella A, Zhang C. "The Times They Are A-Changin'" at Diabetes Care. Diabetes Care 2023 Jan 1; 46 (1):3-5
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  25. Kohlenberg JD, Laurenti MC, Egan AM, Wismayer DS, Bailey KR, Cobelli C, Man CD, Vella A. Differential contribution of alpha and beta cell dysfunction to impaired fasting glucose and impaired glucose tolerance. Diabetologia. 2023 Jan; 66 (1):201-212 Epub 2022 Sept 16
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  26. Sada A, Habermann EB, Szabo Yamashita T, Thompson GB, Lyden ML, Foster TR, Dy BM, Halfdanarson TR, Vella A, McKenzie TJ. Comparison Between Sporadic and Multiple Endocrine Neoplasia Type 1-Associated Insulinoma. J Am Coll Surg. 2022 Nov 1; 235 (5):756-763 Epub 2022 Oct 17
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  27. Egan AM, Galior KD, Maus AD, Fatica E, Simha V, Shah P, Singh RJ, Vella A. Pitfalls in Diagnosing Hypoglycemia Due to Exogenous Insulin: Validation and Utility of an Insulin Analog Assay. Mayo Clin Proc. 2022 Nov; 97(11):1994-2004. Epub 2022 Oct 07.
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  28. Blonde L, Umpierrez GE, Reddy SS, McGill JB, Berga SL, Bush M, Chandrasekaran S, DeFronzo RA, Einhorn D, Galindo RJ, Gardner TW, Garg R, Garvey WT, Hirsch IB, Hurley DL, Izuora K, Kosiborod M, Olson D, Patel SB, Pop-Busui R, Sadhu AR, Samson SL, Stec C, Tamborlane WV Jr, Tuttle KR, Twining C, Vella A, Vellanki P, Weber SL. American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update. Endocr Pract. 2022 Oct; 28 (10):923-1049 Epub 2022 Aug 11
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  29. Dugani SB, Wood-Wentz CM, Mielke MM, Bailey KR, Vella A. Assessment of Disparities in Diabetes Mortality in Adults in US Rural vs Nonrural Counties, 1999-2018. JAMA Netw Open. 2022 Sep 1; 5 (9):e2232318 Epub 2022 Sept 01
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  30. Maselli D, Atieh J, Clark MM, Eckert D, Taylor A, Carlson P, Burton DD, Busciglio I, Harmsen WS, Vella A, Acosta A, Camilleri M. Effects of liraglutide on gastrointestinal functions and weight in obesity: A randomized clinical and pharmacogenomic trial. Obesity (Silver Spring). 2022 Aug; 30 (8):1608-1620
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  31. Adams JD, Egan AM, Laurenti MC, Schembri Wismayer D, Bailey KR, Cobelli C, Dalla Man C, Vella A. The Effect of Diabetes-Associated Variation in TCF7L2 on Postprandial Glucose Metabolism When Glucagon and Insulin Concentrations Are Matched. Metab Syndr Relat Disord. 2022 Aug; 20 (6):329-335 Epub 2022 Apr 18
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  32. James H, Gonsalves WI, Manjunatha S, Dasari S, Lanza IR, Klaus KA, Vella A, Andrews JC, Nair KS. The Effect of Glucagon on Protein Catabolism During Insulin Deficiency: Exchange of Amino Acids Across Skeletal Muscle and the Splanchnic Bed. Diabetes. 2022 Aug 1; 71 (8):1636-1648
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  33. Riddle MC, Bakris G, Blonde L, Boulton AJM, Castle J, DiMeglio L, Gonder-Frederick L, Hu F, Kahn S, Kaul S, Moses R, Rich S, Rosenstock J, Selvin E, Vella A, Wylie-Rosett J, with and on behalf of Associate Editors Vanita Aroda. Editorial Cycles and Continuity of Diabetes Care. Diabetes Care 2022 Jul 7; 45 (7):1493-1494
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  34. Egan AM, Vella A. Tighten Your Belt! Banded Roux-en-Y Gastric Bypass for Diabetes Remission? Diabetes Care. 2022 Jul 7; 45 (7):1495-1497
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  35. Laurenti MC, Arora P, Dalla Man C, Andrews JC, Rizza RA, Matveyenko A, Bailey KR, Cobelli C, Vella A. The relationship between insulin and glucagon concentrations in non-diabetic humans. Physiol Rep. 2022 Jul; 10 (13):e15380
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  36. Ebert SM, Rasmussen BB, Judge AR, Judge SM, Larsson L, Wek RC, Anthony TG, Marcotte GR, Miller MJ, Yorek MA, Vella A, Volpi E, Stern JI, Strub MD, Ryan Z, Talley JJ, Adams CM. Biology of Activating Transcription Factor 4 (ATF4) and Its Role in Skeletal Muscle Atrophy. J Nutr. 2022 Apr 1; 152 (4):926-938
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  37. Ebert SM, Rasmussen BB, Judge AR, Judge SM, Larsson L, Wek RC, Anthony TG, Marcotte GR, Miller MJ, Yorek MA, Vella A, Volpi E, Stern JI, Strub MD, Ryan Z, Talley JJ, Adams CM. Biology of Activating Transcription Factor 4 (ATF4) and Its Role in Skeletal Muscle Atrophy. J Nutr. 2022 Apr; 152 (4):926-938 Epub 2023 Feb 18
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  38. Camilleri M, Vella A. What to do about the leaky gut. Gut. 2022 Feb; 71 (2):424-435 Epub 2021 Sept 11
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  39. Linch F, Thompson S, Fleming C, Vella A, Andrews J. Hepatic Artery Embolization for Palliation of Symptomatic Hypoglycemia in Patients With Hepatic Insulinoma Metastases. J Endocr Soc. 2021 Dec 1; 5 (12):bvab149 Epub 2021 Oct 07
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  40. Adams JD, Egan AM, Laurenti MC, Schembri Wismayer D, Bailey KR, Cobelli C, Dalla Man C, Vella A. Insulin secretion and action and the response of endogenous glucose production to a lack of glucagon suppression in nondiabetic subjects. Am J Physiol Endocrinol Metab. 2021 Nov 1; 321 (5):E728-E736 Epub 2021 Oct 18
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  41. Dugani SB, Christenson LR, Aakre JA, Bui HH, Vella A, Mielke MM. Association of plasma ceramides with prevalent and incident type 2 diabetes mellitus in middle and older aged adults. Diabetes Res Clin Pract. 2021 Sep; 179:108991 Epub 2021 July 29
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  42. Javeed N, Her TK, Brown MR, Vanderboom P, Rakshit K, Egan AM, Vella A, Lanza I, Matveyenko AV. Pro-inflammatory beta cell small extracellular vesicles induce beta cell failure through activation of the CXCL10/CXCR3 axis in diabetes. Cell Rep. 2021 Aug 24; 36 (8):109613
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  43. Kunz HE, Hart CR, Gries KJ, Parvizi M, Laurenti M, Dalla Man C, Moore N, Zhang X, Ryan Z, Polley EC, Jensen MD, Vella A, Lanza IR. Adipose tissue macrophage populations and inflammation are associated with systemic inflammation and insulin resistance in obesity. Am J Physiol Endocrinol Metab. 2021 Jul 1; 321 (1):E105-E121 Epub 2021 May 17
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  44. Dugani SB, Mielke MM, Vella A. Burden and management of type 2 diabetes in rural United States. Diabetes Metab Res Rev. 2021 Jul; 37 (5):e3410 Epub 2020 Oct 05
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  45. Laurenti MC, Matveyenko A, Vella A. Measurement of Pulsatile Insulin Secretion: Rationale and Methodology. Metabolites. 2021 Jun 22; 11 (7) Epub 2021 June 22
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  46. Egan AM, Laurenti MC, Hurtado Andrade MD, Dalla Man C, Cobelli C, Bailey KR, Vella A. Limitations of the fasting proinsulin to insulin ratio as a measure of beta-cell health in people with and without impaired glucose tolerance. Eur J Clin Invest. 2021 Jun; 51 (6):e13469 Epub 2020 Dec 16
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  47. Laurenti MC, Dalla Man C, Varghese RT, Andrews JC, Jones JG, Barosa C, Rizza RA, Matveyenko A, De Nicolao G, Bailey KR, Cobelli C, Vella A. Insulin Pulse Characteristics and Insulin Action in Non-diabetic Humans. J Clin Endocrinol Metab. 2021 May 13; 106 (6):1702-1709
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  48. Dugani SB, Girardo ME, De Filippis E, Mielke MM, Vella A. Risk Factors and Wellness Measures Associated with Prediabetes and Newly Diagnosed Type 2 Diabetes Mellitus in Hispanic Adults. Metab Syndr Relat Disord. 2021 Apr; 19 (3):180-189 Epub 2021 Jan 15
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  49. Sada A, Yamashita TS, Glasgow AE, Habermann EB, Thompson GB, Lyden ML, Dy BM, Halfdanarson TR, Vella A, McKenzie TJ. Comparison of benign and malignant insulinoma. Am J Surg. 2021 Feb; 221 (2):437-447 Epub 2020 Aug 16
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  50. Laurenti MC, Vella A, Adams JD, Schembri Wismayer DJ, Egan AM, Dalla Man C. Assessment of individual and standardized glucagon kinetics in healthy humans. Am J Physiol Endocrinol Metab. 2021 Jan 1; 320 (1):E71-E77 Epub 2020 Nov 02
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  51. Egan AM, Dow ML, Vella A. A Review of the Pathophysiology and Management of Diabetes in Pregnancy. Mayo Clin Proc. 2020 Dec; 95 (12):2734-2746 Epub 2020 July 28
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  52. Kittah E, Camilleri M, Jensen MD, Vella A. A Pilot Study Examining the Effects of GLP-1 Receptor Blockade Using Exendin-(9,39) on Gastric Emptying and Caloric Intake in Subjects With and Without Bariatric Surgery. Metab Syndr Relat Disord. 2020 Nov; 18 (9):406-412 Epub 2020 Aug 20
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  53. Samakkarnthai P, Sfeir JG, Atkinson EJ, Achenbach SJ, Wennberg PW, Dyck PJ, Tweed AJ, Volkman TL, Amin S, Farr JN, Vella A, Drake MT, Khosla S. Determinants of Bone Material Strength and Cortical Porosity in Patients with Type 2 Diabetes Mellitus. J Clin Endocrinol Metab. 2020 Oct 1; 105 (10):e3718-29
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  54. Vargas EJ, Abu Dayyeh BK, Storm AC, Bazerbachi F, Matar R, Vella A, Kellogg T, Stier C. Endoscopic management of dumping syndrome after Roux-en-Y gastric bypass: a large international series and proposed management strategy. Gastrointest Endosc. 2020 Jul; 92 (1):91-96 Epub 2020 Feb 26
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  55. Sada A, Glasgow AE, Vella A, Thompson GB, McKenzie TJ, Habermann EB. Malignant Insulinoma: A Rare Form of Neuroendocrine Tumor. World J Surg. 2020 Jul; 44 (7):2288-2294
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  56. Sharma A, Vella A. Glucose metabolism in Cushing's syndrome. Curr Opin Endocrinol Diabetes Obes. 2020 Jun; 27 (3):140-145
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  57. Egan AM, Vella A. Endoscopic Treatments for Obesity: The Good, the Bad, and the Ugly. Endocrinol Metab Clin North Am. 2020 Jun; 49 (2):315-328 Epub 2020 Apr 11
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  58. Eckhardt BA, Rowsey JL, Thicke BS, Fraser DG, O'Grady KL, Bondar OP, Hines JM, Singh RJ, Thoreson AR, Rakshit K, Lagnado AB, Passos JF, Vella A, Matveyenko AV, Khosla S, Monroe DG, Farr JN. Accelerated osteocyte senescence and skeletal fragility in mice with type 2 diabetes. JCI Insight. 2020 May 7; 5 (9) Epub 2020 May 07
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  59. Calderon G, McRae A, Rievaj J, Davis J, Zandvakili I, Linker-Nord S, Burton D, Roberts G, Reimann F, Gedulin B, Vella A, LaRusso NF, Camilleri M, Gribble FM, Acosta A. Ileo-colonic delivery of conjugated bile acids improves glucose homeostasis via colonic GLP-1-producing enteroendocrine cells in human obesity and diabetes. EBioMedicine. 2020 May; 55:102759 Epub 2020 Apr 25
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  60. Kadouh H, Chedid V, Halawi H, Burton DD, Clark MM, Khemani D, Vella A, Acosta A, Camilleri M. GLP-1 Analog Modulates Appetite, Taste Preference, Gut Hormones, and Regional Body Fat Stores in Adults with Obesity. J Clin Endocrinol Metab. 2020 May 1; 105 (5)
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  61. Laurenti MC, Dalla Man C, Varghese RT, Andrews JC, Rizza RA, Matveyenko A, De Nicolao G, Cobelli C, Vella A. Diabetes-associated genetic variation in TCF7L2 alters pulsatile insulin secretion in humans. JCI Insight. 2020 Apr 9; 5 (7) Epub 2020 Apr 09
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  62. Adams JD, Dalla Man C, Laurenti MC, Andrade MDH, Cobelli C, Rizza RA, Bailey KR, Vella A. Fasting glucagon concentrations are associated with longitudinal decline of beta-cell function in non-diabetic humans. Metabolism. 2020 Apr; 105:154175 Epub 2020 Feb 08
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  63. Mishra R, Akerlund M, Cousminer DL, Ahlqvist E, Bradfield JP, Chesi A, Hodge KM, Guy VC, Brillon DJ, Pratley RE, Rickels MR, Vella A, Ovalle F, Harris RI, Melander O, Varvel S, Hakonarson H, Froguel P, Lonsdale JT, Mauricio D, Schloot NC, Khunti K, Greenbaum CJ, Yderstraede KB, Tuomi T, Voight BF, Schwartz S, Boehm BO, Groop L, Leslie RD, Grant SFA. Genetic Discrimination Between LADA and Childhood-Onset Type 1 Diabetes Within the MHC. Diabetes Care. 2020 Feb; 43 (2):418-425 Epub 2019 Dec 16
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  64. Weivoda MM, Chew CK, Monroe DG, Farr JN, Atkinson EJ, Geske JR, Eckhardt B, Thicke B, Ruan M, Tweed AJ, McCready LK, Rizza RA, Matveyenko A, Kassem M, Andersen TL, Vella A, Drake MT, Clarke BL, Oursler MJ, Khosla S. Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism. Nat Commun. 2020 Jan 7; 11 (1):87 Epub 2020 Jan 07
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  65. Anderson B, Carlson P, Laurenti M, Vella A, Camilleri M, Desai A, Feuerhak K, Bharucha AE. Association between allelic variants in the glucagon-like peptide 1 and cholecystokinin receptor genes with gastric emptying and glucose tolerance. Neurogastroenterol Motil. 2020 Jan; 32 (1):e13724 Epub 2019 Nov 05
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  66. Laurenti MC, Man CD, Varghese RT, Andrews JC, Rizza RA, Matveyenko A, De Nicolao G, Cobelli C, Vella A. Intrahepatic heteropolymerization of M and Z alpha-1-antitrypsin JCI Insight. 2020; 5 (14):e136136
  67. Smushkin G, Sathananthan A, Man CD, Camilleri M, Cobelli C, Rizza RA, Vella A. Letter to the Editor: "Defects in GLP-1 Response to an Oral Challenge Do Not Play a Significant Role in the Pathogenesis of Prediabetes". J Clin Endocrinol Metab 2019 Nov 1; 104 (11):5106-5107
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  68. Egan A, Vella A. TTP399: an investigational liver-selective glucokinase (GK) activator as a potential treatment for type 2 diabetes. Expert Opin Investig Drugs. 2019 Sep; 28 (9):741-747 Epub 2019 Aug 16
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  69. Laurenti MC, Vella A, Varghese RT, Andrews JC, Sharma A, Kittah NE, Rizza RA, Matveyenko A, De Nicolao G, Cobelli C, Dalla Man C. Assessment of pulsatile insulin secretion derived from peripheral plasma C-peptide concentrations by nonparametric stochastic deconvolution. Am J Physiol Endocrinol Metab. 2019 May 1; 316 (5):E687-E694 Epub 2019 Feb 26
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  70. Andrews KL, Dyck PJ, Kavros SJ, Vella A, Kazamel M, Clark V, Litchy WJ, Dyck PJB, Lodermeier KA, Davies JL, Carter RE, Klein CJ. Plantar Ulcers and Neuropathic Arthropathies: Associated Diseases, Polyneuropathy Correlates, and Risk Covariates. Adv Skin Wound Care. 2019 Apr; 32 (4):168-175
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  71. Shah M, Laurenti MC, Dalla Man C, Ma J, Cobelli C, Rizza RA, Vella A. Contribution of endogenous glucagon-like peptide-1 to changes in glucose metabolism and islet function in people with type 2 diabetes four weeks after Roux-en-Y gastric bypass (RYGB). Metabolism. 2019 Apr; 93:10-17 Epub 2018 Dec 23
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  72. Sara JD, Taher R, Kolluri N, Vella A, Lerman LO, Lerman A. Coronary microvascular dysfunction is associated with poor glycemic control amongst female diabetics with chest pain and non-obstructive coronary artery disease. Cardiovasc Diabetol. 2019 Feb 28; 18 (1):22
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  73. Vella A, Freeman JLR, Dunn I, Keller K, Buse JB, Valcarce C. Targeting hepatic glucokinase to treat diabetes with TTP399, a hepatoselective glucokinase activator. Sci Transl Med. 2019 Jan 16; 11 (475)
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  74. Adams JD, Treiber G, Hurtado MD, Laurenti MC, Dalla Man C, Cobelli C, Rizza RA, Vella A. Increased Rates of Meal Absorption Do Not Explain Elevated 1-Hour Glucose in Subjects With Normal Glucose Tolerance. J Endocr Soc. 2019 Jan 1; 3 (1):135-145 Epub 2018 Nov 21
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  75. Hurtado MD, Vella A. What is type 2 diabetes? Medicine (United Kingdom). 2019; 47 (1):10-5
  76. Cousminer DL, Ahlqvist E, Mishra R, Andersen MK, Chesi A, Hawa MI, Davis A, Hodge KM, Bradfield JP, Zhou K, Guy VC, Akerlund M, Wod M, Fritsche LG, Vestergaard H, Snyder J, Hojlund K, Linneberg A, Karajamaki A, Brandslund I, Kim CE, Witte D, Sorgjerd EP, Brillon DJ, Pedersen O, Beck-Nielsen H, Grarup N, Pratley RE, Rickels MR, Vella A, Ovalle F, Melander O, Harris RI, Varvel S, Grill VER, Hakonarson H, Froguel P, Lonsdale JT, Mauricio D, Schloot NC, Khunti K, Greenbaum CJ, Asvold BO, Yderstraede KB, Pearson ER, Schwartz S, Voight BF, Hansen T, Tuomi T, Boehm BO, Groop L, Leslie RD, Grant SFA, Bone Mineral Density in Childhood Study. First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes. Diabetes Care. 2018 Nov; 41 (11):2396-2403 Epub 2018 Sept 25
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  77. Ruetten H, Gebauer M, Raymond RH, Calle RA, Cobelli C, Ghosh A, Robertson RP, Shankar SS, Staten MA, Stefanovski D, Vella A, Wright K, Fryburg DA, Foundation for the NIH Biomarkers Consortium Beta Cell Project Team. Mixed Meal and Intravenous L-Arginine Tests Both Stimulate Incretin Release Across Glucose Tolerance in Man: Lack of Correlation with beta Cell Function. Metab Syndr Relat Disord. 2018 Oct; 16 (8):406-415 Epub 2018 Aug 17
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  78. Adams JD, Vella A. What Can Diabetes-Associated Genetic Variation in TCF7L2 Teach Us About the Pathogenesis of Type 2 Diabetes? Metab Syndr Relat Disord. 2018 Oct; 16 (8):383-389 Epub 2018 July 11
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  79. Moran A, Toffolo G, Schiavon M, Vella A, Klaus K, Cobelli C, Nair KS. A novel triple-tracer approach to assess postprandial protein turnover. Am J Physiol Endocrinol Metab. 2018 Oct 01; 315(4):E469-E477. Epub 2018 Jun 05.
    View PubMed
  80. Vella A, Matveyenko A. Walking a fine line between beta-cell secretion and proliferation. J Biol Chem. 2018 Sep 7; 293 (36):14190-14191
    View PubMed
  81. Salehi M, Vella A, McLaughlin T, Patti ME. Hypoglycemia After Gastric Bypass Surgery: Current Concepts and Controversies. J Clin Endocrinol Metab. 2018 Aug 1; 103 (8):2815-2826
    View PubMed
  82. Karanth S, Adams JD, Serrano MLA, Quittner-Strom EB, Simcox J, Villanueva CJ, Ozcan L, Holland WL, Yost HJ, Vella A, Schlegel A. A Hepatocyte FOXN3-alpha Cell Glucagon Axis Regulates Fasting Glucose. Cell Rep. 2018 Jul 10; 24 (2):312-319
    View PubMed
  83. Tack J, Aberle J, Arts J, Laville M, Oppert JM, Bender G, Bhoyrul S, McLaughlin T, Yoshikawa T, Vella A, Zhou J, Passos VQ, O'Connell P, Van Beek AP. Safety and efficacy of pasireotide in dumping syndrome-results from a phase 2, multicentre study. Aliment Pharmacol Ther. 2018 Jun; 47 (12):1661-1672 Epub 2018 Apr 25
    View PubMed
  84. Shankar SS, Lee DS, Raymond RH, Calle RA, Cobelli C, Ghosh A, Robertson RP, Ruetten H, Staten MA, Stefanovski D, Vella A, Whitaker S, Fryburg DA, Foundation for the NIH Biomarkers Consortium Beta Cell Project Team. Outpatient versus inpatient mixed meal tolerance and arginine stimulation testing yields comparable measures of variability for assessment of beta cell function. Contemp Clin Trials Commun. 2018 Jun; 10:94-99 Epub 2018 Mar 29
    View PubMed
  85. Bogachus LD, Bellin MD, Vella A, Robertson RP. Deficient Glucagon Response to Hypoglycemia During a Mixed Meal in Total Pancreatectomy/Islet Autotransplantation Recipients. J Clin Endocrinol Metab. 2018 Apr 1; 103 (4):1522-1529
    View PubMed
  86. Varghese RT, Dalla Man C, Laurenti MC, Piccinini F, Sharma A, Shah M, Bailey KR, Rizza RA, Cobelli C, Vella A. Performance of individually measured vs population-based C-peptide kinetics to assess beta-cell function in the presence and absence of acute insulin resistance. Diabetes Obes Metab. 2018 Mar; 20 (3):549-555 Epub 2017 Sept 27
    View PubMed
  87. Ikramuddin S, Korner J, Lee WJ, Thomas AJ, Connett JE, Bantle JP, Leslie DB, Wang Q, Inabnet WB 3rd, Jeffery RW, Chong K, Chuang LM, Jensen MD, Vella A, Ahmed L, Belani K, Billington CJ. Lifestyle Intervention and Medical Management With vs Without Roux-en-Y Gastric Bypass and Control of Hemoglobin A1c, LDL Cholesterol, and Systolic Blood Pressure at 5 Years in the Diabetes Surgery Study. JAMA. 2018 Jan 16; 319 (3):266-278
    View PubMed
  88. Ma J, Vella A. What Has Bariatric Surgery Taught Us About the Role of the Upper Gastrointestinal Tract in the Regulation of Postprandial Glucose Metabolism? Front Endocrinol (Lausanne). 2018; 9:324 Epub 2018 June 26
    View PubMed
  89. Sharma A, Varghese RT, Shah M, Man CD, Cobelli C, Rizza RA, Bailey KR, Vella A. Impaired Insulin Action Is Associated With Increased Glucagon Concentrations in Nondiabetic Humans. J Clin Endocrinol Metab. 2018 Jan 1; 103 (1):314-319
    View PubMed
  90. Thompson SM, Vella A, Service FJ, Thompson G, Andrews JC. Selective Arterial Calcium Stimulation with Hepatic Venous Sampling in Patients with Recurrent Endogenous Hyperinsulinemic Hypoglycemia and Metastatic Insulinoma: Evaluation in Five Patients. J Vasc Interv Radiol. 2017 Dec; 28 (12):1745-1749
    View PubMed
  91. Halawi H, Khemani D, Eckert D, O'Neill J, Kadouh H, Grothe K, Clark MM, Burton DD, Vella A, Acosta A, Zinsmeister AR, Camilleri M. Effects of liraglutide on weight, satiation, and gastric functions in obesity: a randomised, placebo-controlled pilot trial. Lancet Gastroenterol Hepatol. 2017 Dec; 2 (12):890-899 Epub 2017 Sept 27
    View PubMed
  92. Vella A, Camilleri M. The Gastrointestinal Tract as an Integrator of Mechanical and Hormonal Response to Nutrient Ingestion. Diabetes. 2017 Nov; 66 (11):2729-2737
    View PubMed
  93. Bogachus LD, Oseid E, Bellin M, Vella A, Robertson RP. Deficient Endogenous Glucose Production During Exercise After Total Pancreatectomy/Islet Autotransplantation. J Clin Endocrinol Metab. 2017 Sep 1; 102 (9):3288-3295
    View PubMed
  94. Donegan D, Jakubikova I, Vella A. ANTHROPOMETRIC FEATURES ARE NOT PREDICTIVE OF 72-HOUR FAST DURATION IN INSULINOMAS. Endocr Pract. 2017 Aug; 23 (8):923-928 Epub 2017 June 14
    View PubMed
  95. Sharma A, Laurenti MC, Dalla Man C, Varghese RT, Cobelli C, Rizza RA, Matveyenko A, Vella A. Glucose metabolism during rotational shift-work in healthcare workers. Diabetologia. 2017 Aug; 60 (8):1483-1490 Epub 2017 May 27
    View PubMed
  96. Kittah NE, Vella A. MANAGEMENT OF ENDOCRINE DISEASE: Pathogenesis and management of hypoglycemia. Eur J Endocrinol. 2017 Jul; 177 (1):R37-R47 Epub 2017 Apr 05
    View PubMed
  97. Thompson SM, Vella A, Service FJ, Andrews JC. Selective Arterial Calcium Stimulation With Hepatic Venous Sampling in Immune-Mediated Hypoglycemia. J Endocr Soc. 2017 Jun 1; 1 (6):671-675 Epub 2017 May 04
    View PubMed
  98. Chong K, Ikramuddin S, Lee WJ, Billington CJ, Bantle JP, Wang Q, Thomas AJ, Connett JE, Leslie DB, Inabnet WB 3rd, Jeffery RW, Sarr MG, Jensen MD, Vella A, Ahmed L, Belani K, Schone JL, Olofson AE, Bainbridge HA, Laqua PS, Korner J, Chuang LM. National Differences in Remission of Type 2 Diabetes Mellitus After Roux-en-Y Gastric Bypass Surgery-Subgroup Analysis of 2-Year Results of the Diabetes Surgery Study Comparing Taiwanese with Americans with Mild Obesity (BMI 30-35 kg/m(2)). Obes Surg. 2017 May; 27 (5):1189-1195
    View PubMed
  99. Lu J, Varghese RT, Zhou L, Vella A, Jensen MD. Glucose tolerance and free fatty acid metabolism in adults with variations in TCF7L2 rs7903146. Metabolism. 2017 Mar; 68:55-63 Epub 2016 Dec 09
    View PubMed
  100. Newhouse LP, Joyner MJ, Curry TB, Laurenti MC, Man CD, Cobelli C, Vella A, Limberg JK. Three hours of intermittent hypoxia increases circulating glucose levels in healthy adults. Physiol Rep. 2017 Jan; 5 (1) Epub 2017 Jan 13
    View PubMed
  101. Sharma A, Vella A. Obstacles to Translating Genotype-Phenotype Correlates in Metabolic Disease. Physiology (Bethesda). 2017 Jan; 32 (1):42-50
    View PubMed
  102. Varghese RT, Dalla Man C, Sharma A, Viegas I, Barosa C, Marques C, Shah M, Miles JM, Rizza RA, Jones JG, Cobelli C, Vella A. Mechanisms Underlying the Pathogenesis of Isolated Impaired Glucose Tolerance in Humans. J Clin Endocrinol Metab. 2016 Dec; 101 (12):4816-4824 Epub 2016 Sept 07
    View PubMed
  103. Piccinini F, Dalla Man C, Vella A, Cobelli C. A model for the estimation of hepatic insulin extraction after a meal IEEE Transactions On Biomedical Engineering. 2016 Sep; 63: (9)1925-32.
  104. Ikramuddin S, Korner J, Lee WJ, Bantle JP, Thomas AJ, Connett JE, Leslie DB, Inabnet WB 3rd, Wang Q, Jeffery RW, Chong K, Chuang LM, Jensen MD, Vella A, Ahmed L, Belani K, Olofson AE, Bainbridge HA, Billington CJ. Durability of Addition of Roux-en-Y Gastric Bypass to Lifestyle Intervention and Medical Management in Achieving Primary Treatment Goals for Uncontrolled Type 2 Diabetes in Mild to Moderate Obesity: A Randomized Control Trial. Diabetes Care. 2016 Sep; 39 (9):1510-8 Epub 2016 June 16
    View PubMed
  105. Shankar SS, Vella A, Raymond RH, Staten MA, Calle RA, Bergman RN, Cao C, Chen D, Cobelli C, Dalla Man C, Deeg M, Dong JQ, Lee DS, Polidori D, Robertson RP, Ruetten H, Stefanovski D, Vassileva MT, Weir GC, Fryburg DA, Foundation for the National Institutes of Health beta-Cell Project Team. Standardized Mixed-Meal Tolerance and Arginine Stimulation Tests Provide Reproducible and Complementary Measures of beta-Cell Function: Results From the Foundation for the National Institutes of Health Biomarkers Consortium Investigative Series. Diabetes Care. 2016 Sep; 39 (9):1602-13 Epub 2016 July 12
    View PubMed
  106. Varghese RT, Viegas I, Barosa C, Marques C, Shah M, Rizza RA, Jones JG, Vella A. Diabetes-Associated Variation in TCF7L2 Is Not Associated With Hepatic or Extrahepatic Insulin Resistance. Diabetes. 2016 Apr; 65 (4):887-92 Epub 2016 Jan 28
    View PubMed
  107. Shah M, Varghese RT, Miles JM, Piccinini F, Dalla Man C, Cobelli C, Bailey KR, Rizza RA, Vella A. TCF7L2 Genotype and alpha-Cell Function in Humans Without Diabetes. Diabetes. 2016 Feb; 65 (2):371-80 Epub 2015 Nov 02
    View PubMed
  108. Dalla Man C, Micheletto F, Sathananthan M, Vella A, Cobelli C. Model-Based Quantification of Glucagon-Like Peptide-1-Induced Potentiation of Insulin Secretion in Response to a Mixed Meal Challenge. Diabetes Technol Ther. 2016 Jan; 18 (1):39-46
    View PubMed
  109. Thompson SM, Vella A, Thompson GB, Rumilla KM, Service FJ, Grant CS, Andrews JC. Selective Arterial Calcium Stimulation With Hepatic Venous Sampling Differentiates Insulinoma From Nesidioblastosis. J Clin Endocrinol Metab. 2015 Nov; 100 (11):4189-97 Epub 2015 Aug 27
    View PubMed
  110. Sathananthan M, Shah M, Edens KL, Grothe KB, Piccinini F, Farrugia LP, Micheletto F, Man CD, Cobelli C, Rizza RA, Camilleri M, Vella A. Six and 12 Weeks of Caloric Restriction Increases beta Cell Function and Lowers Fasting and Postprandial Glucose Concentrations in People with Type 2 Diabetes. J Nutr. 2015 Sep; 145 (9):2046-51 Epub 2015 Aug 05
    View PubMed
  111. Nguyen KT, Billington CJ, Vella A, Wang Q, Ahmed L, Bantle JP, Bessler M, Connett JE, Inabnet WB, Thomas A, Ikramuddin S, Korner J. Preserved Insulin Secretory Capacity and Weight Loss Are the Predominant Predictors of Glycemic Control in Patients With Type 2 Diabetes Randomized to Roux-en-Y Gastric Bypass. Diabetes. 2015 Sep; 64 (9):3104-10 Epub 2015 Apr 21
    View PubMed
  112. Thompson SM, Vella A, Service FJ, Grant CS, Thompson GB, Andrews JC. Impact of variant pancreatic arterial anatomy and overlap in regional perfusion on the interpretation of selective arterial calcium stimulation with hepatic venous sampling for preoperative localization of occult insulinoma. Surgery. 2015 Jul; 158 (1):162-72 Epub 2015 Apr 11
    View PubMed
  113. Ikramuddin S, Billington CJ, Lee WJ, Bantle JP, Thomas AJ, Connett JE, Leslie DB, Inabnet WB 3rd, Jeffery RW, Chong K, Chuang LM, Sarr MG, Jensen MD, Vella A, Ahmed L, Belani K, Schone JL, Olofson AE, Bainbridge HA, Laqua PS, Wang Q, Korner J. Roux-en-Y gastric bypass for diabetes (the Diabetes Surgery Study): 2-year outcomes of a 5-year, randomised, controlled trial. Lancet Diabetes Endocrinol. 2015 Jun; 3 (6):413-422 Epub 2015 May 12
    View PubMed
  114. Javed A, Balagopal PB, Vella A, Fischer PR, Piccinini F, Dalla Man C, Cobelli C, Giesler PD, Laugen JM, Kumar S. Association between thyrotropin levels and insulin sensitivity in euthyroid obese adolescents. Thyroid. 2015 May; 25 (5):478-84 Epub 2015 Apr 07
    View PubMed
  115. Matveyenko A, Vella A. Regenerative medicine in diabetes. Mayo Clin Proc. 2015 Apr; 90 (4):546-54
    View PubMed
  116. Acosta A, Camilleri M, Shin A, Vazquez-Roque MI, Iturrino J, Lanza IR, Nair KS, Burton D, O'Neill J, Eckert D, Carlson P, Vella A, Zinsmeister AR. Association of UCP-3 rs1626521 with obesity and stomach functions in humans. Obesity (Silver Spring). 2015 Apr; 23 (4):898-906 Epub 2015 Mar 07
    View PubMed
  117. Bharucha AE, Kudva Y, Basu A, Camilleri M, Low PA, Vella A, Zinsmeister AR. Relationship between glycemic control and gastric emptying in poorly controlled type 2 diabetes. Clin Gastroenterol Hepatol. 2015 Mar; 13 (3):466-476.e1 Epub 2014 July 17
    View PubMed
  118. Javed A, Vella A, Balagopal PB, Fischer PR, Weaver AL, Piccinini F, Dalla Man C, Cobelli C, Giesler PD, Laugen JM, Kumar S. Cholecalciferol supplementation does not influence beta-cell function and insulin action in obese adolescents: a prospective double-blind randomized trial. J Nutr. 2015 Feb; 145 (2):284-90 Epub 2014 Dec 17
    View PubMed
  119. Ikramuddin S, Korner J, Lee WJ, Connett JE, Inabnet WB, Billington CJ, Thomas AJ, Leslie DB, Chong K, Jeffery RW, Ahmed L, Vella A, Chuang LM, Bessler M, Sarr MG, Swain JM, Laqua P, Jensen MD, Bantle JP. Roux-en-Y gastric bypass vs intensive medical management for the control of type 2 diabetes, hypertension, and hyperlipidemia: The Diabetes Surgery Study randomized clinical trial. Diabetes Technology and Therapeutics. 2015; 17:S77-8.
  120. Krause ML, Norgan A, Vella A, Beckman TJ, Warrington KJ. Concomitant giant cell arteritis and secondary adrenal insufficiency. Scand J Rheumatol 2015; 44 (6):517-9 Epub 2015 July 14
    View PubMed
  121. Hames KC, Vella A, Kemp BJ, Jensen MD. Free fatty acid uptake in humans with CD36 deficiency. Diabetes. 2014 Nov; 63 (11):3606-14 Epub 2014 June 10
    View PubMed
  122. Shah M, Vella A. Effects of GLP-1 on appetite and weight. Rev Endocr Metab Disord. 2014 Sep; 15 (3):181-7
    View PubMed
  123. Shah M, Law JH, Micheletto F, Sathananthan M, Dalla Man C, Cobelli C, Rizza RA, Camilleri M, Zinsmeister AR, Vella A. Contribution of endogenous glucagon-like peptide 1 to glucose metabolism after Roux-en-Y gastric bypass. Diabetes. 2014 Feb; 63 (2):483-93 Epub 2013 Oct 02
    View PubMed
  124. Cobelli C, Man CD, Toffolo G, Basu R, Vella A, Rizza R. The oral minimal model method. Diabetes. 2014; 63(4):1203-13.
    View PubMed
  125. Sathananthan M, Ikramuddin S, Swain JM, Shah M, Piccinini F, Dalla Man C, Cobelli C, Rizza RA, Camilleri M, Vella A. The effect of vagal nerve blockade using electrical impulses on glucose metabolism in nondiabetic subjects. Diabetes Metab Syndr Obes. 2014; 7:305-12 Epub 2014 July 11
    View PubMed
  126. Ikramuddin S, Korner J, Lee WJ, Connett JE, Inabnet WB, Billington CJ, Thomas AJ, Leslie DB, Chong K, Jeffery RW, Ahmed L, Vella A, Chuang LM, Bessler M, Sarr MG, Swain JM, Laqua P, Jensen PD, Bantle JP. Roux-en-Y gastric bypass vs intensive medical management for the control of type 2 diabetes, hypertension, and hyperlipidemia. Diabetes Technology and Therapeutics. 2014; 16(Suppl 1):S79-80.
  127. Prutsky GJ, Domecq JP, Wang Z, Carranza Leon BG, Elraiyah T, Nabhan M, Sundaresh V, Vella A, Montori VM, Murad MH. Glucose targets in pregnant women with diabetes: a systematic review and meta-analysis. J Clin Endocrinol Metab. 2013 Nov; 98 (11):4319-24 Epub 2013 Oct 22
    View PubMed
  128. Prutsky GJ, Domecq JP, Sundaresh V, Elraiyah T, Nabhan M, Prokop LJ, Vella A, Montori VM, Murad MH. Screening for gestational diabetes: a systematic review and meta-analysis. J Clin Endocrinol Metab. 2013 Nov; 98 (11):4311-8 Epub 2013 Oct 22
    View PubMed
  129. Shin A, Camilleri M, Busciglio I, Burton D, Smith SA, Vella A, Ryks M, Rhoten D, Zinsmeister AR. The ghrelin agonist RM-131 accelerates gastric emptying of solids and reduces symptoms in patients with type 1 diabetes mellitus. Clin Gastroenterol Hepatol. 2013 Nov; 11 (11):1453-1459.e4 Epub 2013 Apr 30
    View PubMed
  130. Sathananthan M, Farrugia LP, Miles JM, Piccinini F, Dalla Man C, Zinsmeister AR, Cobelli C, Rizza RA, Vella A. Direct effects of exendin-(9,39) and GLP-1-(9,36)amide on insulin action, beta-cell function, and glucose metabolism in nondiabetic subjects. Diabetes. 2013 Aug; 62 (8):2752-6 Epub 2013 Apr 01
    View PubMed
  131. Ikramuddin S, Korner J, Lee WJ, Connett JE, Inabnet WB, Billington CJ, Thomas AJ, Leslie DB, Chong K, Jeffery RW, Ahmed L, Vella A, Chuang LM, Bessler M, Sarr MG, Swain JM, Laqua P, Jensen MD, Bantle JP. Roux-en-Y gastric bypass vs intensive medical management for the control of type 2 diabetes, hypertension, and hyperlipidemia: the Diabetes Surgery Study randomized clinical trial. JAMA. 2013 Jun 5; 309(21):2240-9.
    View PubMed
  132. Smushkin G, Sathananthan M, Piccinini F, Dalla Man C, Law JH, Cobelli C, Zinsmeister AR, Rizza RA, Vella A. The effect of a bile acid sequestrant on glucose metabolism in subjects with type 2 diabetes. Diabetes. 2013 Apr; 62 (4):1094-101 Epub 2012 Dec 18
    View PubMed
  133. Donegan DM, Vella A. 69-year-old man with recurrent episodes of confusion and diaphoresis. Mayo Clin Proc. 2013 Apr; 88(4):410-3.
    View PubMed
  134. Ketha S, Smithedajkul P, Vella A, Pruthi R, Wysokinski W, McBane R. Adrenal haemorrhage due to heparin-induced thrombocytopenia. Thromb Haemost. 2013 Apr; 109(4):669-75. Epub 2013 Feb 07.
    View PubMed
  135. Shin A, Camilleri M, Busciglio I, Burton D, Stoner E, Noonan P, Gottesdiener K, Smith SA, Vella A, Zinsmeister AR. Randomized controlled phase Ib study of ghrelin agonist, RM-131, in type 2 diabetic women with delayed gastric emptying: pharmacokinetics and pharmacodynamics. Diabetes Care. 2013 Jan; 36 (1):41-8 Epub 2012 Sept 06
    View PubMed
  136. Vella A, Kumar R. Osteocalcin and the regulation of glucose metabolism. Clinical Reviews in Bone and Mineral Metabolism. 2013; 11(1):11-6.
    View PubMed
  137. Dyck PJ, Overland CJ, Low PA, Litchy WJ, Davies JL, Dyck PJ, Dyck PJ, Carter RE, Melton LJ, Andersen H, Melton LJ, Albers JW, Bolton CF, England JD, Klein CJ, Llewelyn G, Mauermann ML, Russell JW, Selvarajah D, Singer W, Smith AG, Tesfaye S, Vella A. "Unequivocally Abnormal" vs "Usual" Signs and Symptoms for Proficient Diagnosis of Diabetic Polyneuropathy: Cl vs N Phys Trial. Arch Neurol. 2012 Dec; 69 (12):1609-14
    View PubMed
  138. Smushkin G, Sathananthan M, Sathananthan A, Dalla Man C, Micheletto F, Zinsmeister AR, Cobelli C, Vella A. Diabetes-associated common genetic variation and its association with GLP-1 concentrations and response to exogenous GLP-1. Diabetes. 2012 May; 61 (5):1082-9 Epub 2012 Mar 28
    View PubMed
  139. Erickson D, Singh RJ, Sathananthan A, Vella A, Bryant SC. Late-night salivary cortisol for diagnosis of Cushing's syndrome by liquid chromatography/tandem mass spectrometry assay. Clin Endocrinol (Oxf). 2012 Apr; 76(4):467-72.
    View PubMed
  140. Smushkin G, Sathananthan A, Man CD, Zinsmeister AR, Camilleri M, Cobelli C, Rizza RA, Vella A. Defects in GLP-1 response to an oral challenge do not play a significant role in the pathogenesis of prediabetes. J Clin Endocrinol Metab. 2012 Feb; 97 (2):589-98 Epub 2011 Nov 16
    View PubMed
  141. Sathananthan A, Dalla Man C, Zinsmeister AR, Camilleri M, Rodeheffer RJ, Toffolo G, Cobelli C, Rizza RA, Vella A. A concerted decline in insulin secretion and action occurs across the spectrum of fasting and postchallenge glucose concentrations. Clin Endocrinol (Oxf). 2012 Feb; 76 (2):212-9
    View PubMed
  142. Singh E, Vella A. Hypoglycemia after gastric bypass surgery. Diabetes Spectrum. 2012; 25(4):217-21.
  143. Levy MJ, Thompson GB, Topazian MD, Callstrom MR, Grant CS, Vella A. US-guided ethanol ablation of insulinomas: a new treatment option. Gastrointest Endosc. 2012 Jan; 75 (1):200-6 Epub 2011 Nov 10
    View PubMed
  144. Vazquez-Roque MI, Camilleri M, Vella A, Carlson P, Laugen J, Zinsmeister AR. Association of genetic variation in cannabinoid mechanisms and gastric motor functions and satiation in overweight and obesity. Neurogastroenterol Motil. 2011 Jul; 23 (7):637-e257 Epub 2011 Apr 07
    View PubMed
  145. Vazquez-Roque MI, Camilleri M, Vella A, Carlson P, Laugen J, Zinsmeister AR. Association of TCF7L2 allelic variations with gastric function, satiation, and GLP-1 levels. Clin Transl Sci. 2011 Jun; 4 (3):183-7
    View PubMed
  146. Kumar R, Vella A. Carbohydrate metabolism and the skeleton: picking a bone with the beta-cell. J Clin Endocrinol Metab. 2011 May; 96 (5):1269-71 Epub 2011 Feb 23
    View PubMed
  147. Richards ML, Thompson GB, Farley DR, Kendrick ML, Service JF, Vella A, Grant CS. Setting the bar for laparoscopic resection of sporadic insulinoma. World J Surg. 2011 Apr; 35 (4):785-9
    View PubMed
  148. Vanderveen KA, Grant CS, Thompson GB, Farley DR, Richards ML, Vella A, Vollrath B, Service FJ. Outcomes and quality of life after partial pancreatectomy for noninsulinoma pancreatogenous hypoglycemia from diffuse islet cell disease. Surgery. 2010 Dec; 148 (6):1237-45; discussion 1245-6
    View PubMed
  149. Kumar R, Binkley N, Vella A. Effect of phylloquinone supplementation on glucose homeostasis in humans. Am J Clin Nutr. 2010 Dec; 92 (6):1528-32 Epub 2010 Sept 29
    View PubMed
  150. Smushkin G, Vella A. What is type 2 diabetes? Medicine (Abingdon). 2010 Nov 1; 38 (11):597-601
    View PubMed
  151. Benavente-Chenhalls LA, Vella A, Farley DR, Thompson GB, Grant CS, Richards ML. Malignant adrenal neoplasm masquerading as worrisome adrenal hemorrhage. Ann Surg Oncol. 2010 Oct; 17 (10):2710-3 Epub 2010 May 25
    View PubMed
  152. Sathananthan A, Man CD, Micheletto F, Zinsmeister AR, Camilleri M, Giesler PD, Laugen JM, Toffolo G, Rizza RA, Cobelli C, Vella A. Common genetic variation in GLP1R and insulin secretion in response to exogenous GLP-1 in nondiabetic subjects: a pilot study. Diabetes Care. 2010 Sep; 33 (9):2074-6
    View PubMed
  153. Dyck PJ, Overland CJ, Low PA, Litchy WJ, Davies JL, Dyck PJ, O'Brien PC, Cl vs. NPhys Trial Investigators, Albers JW, Andersen H, Bolton CF, England JD, Klein CJ, Llewelyn JG, Mauermann ML, Russell JW, Singer W, Smith AG, Tesfaye S, Vella A. Signs and symptoms versus nerve conduction studies to diagnose diabetic sensorimotor polyneuropathy: Cl vs. NPhys trial. Muscle Nerve. 2010 Aug; 42(2):157-64.
    View PubMed
  154. Bock G, Dalla Man C, Micheletto F, Basu R, Giesler PD, Laugen J, Deacon CF, Holst JJ, Toffolo G, Cobelli C, Rizza RA, Vella A. The effect of DPP-4 inhibition with sitagliptin on incretin secretion and on fasting and postprandial glucose turnover in subjects with impaired fasting glucose. Clin Endocrinol (Oxf). 2010 Aug; 73 (2):189-96 Epub 2009 Dec 18
    View PubMed
  155. Smushkin G, Vella A. Genetics of type 2 diabetes. Curr Opin Clin Nutr Metab Care. 2010 Jul; 13 (4):471-7
    View PubMed
  156. Dalla Man C, Micheletto F, Sathananthan A, Rizza RA, Vella A, Cobelli C. A model of GLP-1 action on insulin secretion in nondiabetic subjects. Am J Physiol Endocrinol Metab. 2010 Jun; 298(6):E1115-21. Epub 2010 Feb 23.
    View PubMed
  157. Papathanasopoulos A, Camilleri M, Carlson PJ, Vella A, Nord SJ, Burton DD, Odunsi ST, Zinsmeister AR. A preliminary candidate genotype-intermediate phenotype study of satiation and gastric motor function in obesity. Obesity (Silver Spring). 2010 Jun; 18 (6):1201-11 Epub 2009 Oct 29
    View PubMed
  158. Erickson D, Erickson B, Watson R, Patton A, Atkinson J, Meyer F, Nippoldt T, Carpenter P, Natt N, Vella A, Thapa P. 3 Tesla magnetic resonance imaging with and without corticotropin releasing hormone stimulation for the detection of microadenomas in Cushing's syndrome. Clin Endocrinol (Oxf). 2010 Jun; 72(6):793-9. Epub 2009 Oct 07.
    View PubMed
  159. Vella A, Rizza RA. Application of isotopic techniques using constant specific activity or enrichment to the study of carbohydrate metabolism. Diabetes. 2009 Oct; 58 (10):2168-74
    View PubMed
  160. Samsom M, Bharucha A, Gerich JE, Herrmann K, Limmer J, Linke R, Maggs D, Schirra J, Vella A, Worle HJ, Goke B. Diabetes mellitus and gastric emptying: questions and issues in clinical practice. Diabetes Metab Res Rev. 2009 Sep; 25(6):502-14.
    View PubMed
  161. Sathananthan A, Vella A. Personalized pharmacotherapy for Type 2 diabetes mellitus. Per Med. 2009 Jul 1; 6(4):417-422.
    View PubMed
  162. Vella A. Pharmacogenetics for type 2 diabetes: practical considerations for study design. J Diabetes Sci Technol. 2009 Jul 1; 3 (4):705-9 Epub 2009 July 01
    View PubMed
  163. Smushkin G, Vella A. Inhibition of dipeptidyl peptidase-4: The mechanisms of action and clinical use of vildagliptin for the management of type 2 diabetes. Diabetes Metab Syndr Obes. 2009 Jun 12; 2:83-90 Epub 2009 June 12
    View PubMed
  164. Brown DL, Henrichsen TL, Clayton AC, Hudson SB, Coddington CC 3rd, Vella A. Ovarian stromal hyperthecosis: sonographic features and histologic associations. J Ultrasound Med. 2009 May; 28 (5):587-93
    View PubMed
  165. Placzkowski KA, Vella A, Thompson GB, Grant CS, Reading CC, Charboneau JW, Andrews JC, Lloyd RV, Service FJ. Secular trends in the presentation and management of functioning insulinoma at the Mayo Clinic, 1987-2007. J Clin Endocrinol Metab. 2009 Apr; 94 (4):1069-73 Epub 2009 Jan 13
    View PubMed
  166. Rumilla KM, Erickson LA, Service FJ, Vella A, Thompson GB, Grant CS, Lloyd RV. Hyperinsulinemic hypoglycemia with nesidioblastosis: histologic features and growth factor expression. Mod Pathol. 2009 Feb; 22 (2):239-45 Epub 2008 Oct 17
    View PubMed
  167. Dalla Man C, Bock G, Giesler PD, Serra DB, Ligueros Saylan M, Foley JE, Camilleri M, Toffolo G, Cobelli C, Rizza RA, Vella A. Dipeptidyl peptidase-4 inhibition by vildagliptin and the effect on insulin secretion and action in response to meal ingestion in type 2 diabetes. Diabetes Care. 2009 Jan; 32(1):14-8. Epub 2008 Oct 17.
    View PubMed
  168. Arruda-Olson AM, Patch RK 3rd, Leibson CL, Vella A, Frye RL, Weston SA, Killian JM, Roger VL. Effect of second-generation sulfonylureas on survival in patients with diabetes mellitus after myocardial infarction. Mayo Clin Proc. 2009; 84 (1):28-33
    View PubMed
  169. Vella A, Bock G, Giesler PD, Burton DB, Serra DB, Saylan ML, Deacon CF, Foley JE, Rizza RA, Camilleri M. The effect of dipeptidyl peptidase-4 inhibition on gastric volume, satiation and enteroendocrine secretion in type 2 diabetes: a double-blind, placebo-controlled crossover study. Clin Endocrinol (Oxf). 2008 Nov; 69 (5):737-44 Epub 2008 Mar 10
    View PubMed
  170. Roberts RO, Geda YE, Knopman DS, Christianson TJ, Pankratz VS, Boeve BF, Vella A, Rocca WA, Petersen RC. Association of duration and severity of diabetes mellitus with mild cognitive impairment. Arch Neurol. 2008 Aug; 65 (8):1066-73
    View PubMed
  171. Szarka LA, Camilleri M, Vella A, Burton D, Baxter K, Simonson J, Zinsmeister AR. A stable isotope breath test with a standard meal for abnormal gastric emptying of solids in the clinic and in research. Clin Gastroenterol Hepatol. 2008 Jun; 6 (6):635-643.e1 Epub 2008 Apr 14
    View PubMed
  172. Porterfield JR, Thompson GB, Young WF Jr, Chow JT, Fryrear RS, van Heerden JA, Farley DR, Atkinson JL, Meyer FB, Abboud CF, Nippoldt TB, Natt N, Erickson D, Vella A, Carpenter PC, Richards M, Carney JA, Larson D, Schleck C, Churchward M, Grant CS. Surgery for Cushing's syndrome: an historical review and recent ten-year experience. World J Surg. 2008 May; 32 (5):659-77
    View PubMed
  173. Young WF Jr, du Plessis H, Thompson GB, Grant CS, Farley DR, Richards ML, Erickson D, Vella A, Stanson AW, Carney JA, Abboud CF, Carpenter PC. The clinical conundrum of corticotropin-independent autonomous cortisol secretion in patients with bilateral adrenal masses. World J Surg. 2008 May; 32 (5):856-62
    View PubMed
  174. Atkinson JL, Young WF Jr, Meyer FB, Davis DH, Nippoldt TB, Erickson D, Vella A, Natt N, Abboud CF, Carpenter PC. Sublabial transseptal vs transnasal combined endoscopic microsurgery in patients with Cushing disease and MRI-depicted microadenomas. Mayo Clin Proc. 2008 May; 83(5):550-3.
    View PubMed
  175. Vella A, Camilleri M. Pharmacogenetics: potential role in the treatment of diabetes and obesity. Expert Opin Pharmacother. 2008 May; 9 (7):1109-19
    View PubMed
  176. Vella A, Bouatia-Naji N, Heude B, Cooper JD, Lowe CE, Petry C, Ring SM, Dunger DB, Todd JA, Ong KK. Association analysis of the IGF1 gene with childhood growth, IGF-1 concentrations and type 1 diabetes. Diabetologia. 2008 May; 51(5):811-5. Epub 2008 Mar 04.
    View PubMed
  177. Cooper JD, Smyth DJ, Bailey R, Payne F, Downes K, Godfrey LM, Masters J, Zeitels LR, Vella A, Walker NM, Todd JA. The candidate genes TAF5L, TCF7, PDCD1, IL6 and ICAM1 cannot be excluded from having effects in type 1 diabetes - art. no. 71. BMC Medical Genetics. 2007 Nov 28; 8:71.
  178. Todd JA, Walker NM, Cooper JD, Smyth DJ, Downes K, Plagnol V, Bailey R, Nejentsev S, Field SF, Payne F, Lowe CE, Szeszko JS, Hafler JP, Zeitels L, Yang JH, Vella A, Nutland S, Stevens HE, Schuilenburg H, Coleman G, Maisuria M, Meadows W, Smink LJ, Healy B, Burren OS, Lam AA, Ovington NR, Allen J, Adlem E, Leung HT, Wallace C, Howson JM, Guja C, Ionescu-Tirgoviste C, Genetics of Type 1 Diabetes in Finland, Simmonds MJ, Heward JM, Gough SC, Wellcome Trust Case Control Consortium, Dunger DB, Wicker LS, Clayton DG. Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat Genet. 2007 Jul; 39(7):857-64 Epub 2007 Jun 6.
    View PubMed
  179. Vella A, Bock G, Giesler PD, Burton DB, Serra DB, Saylan ML, Dunning BE, Foley JE, Rizza RA, Camilleri M. Effects of dipeptidyl peptidase-4 inhibition on gastrointestinal function, meal appearance, and glucose metabolism in type 2 diabetes. Diabetes. 2007 May; 56 (5):1475-80 Epub 2007 Feb 15
    View PubMed
  180. Dingli D, Wolf RC, Vella A. Imatinib and type 2 diabetes. Endocr Pract. 2007 Mar-Apr; 13 (2):126-30
    View PubMed
  181. Cooper JD, Smyth DJ, Bailey R, Payne F, Downes K, Godfrey LM, Masters J, Zeitels LR, Vella A, Walker NM, Todd JA. The candidate genes TAF5L, TCF7, PDCD1, IL6 and ICAM1 cannot be excluded from having effects in type 1 diabetes. BMC Med Genet. 2007; 8.
  182. Ortu M, Vaccarezza M, Trovati S, Galli M, Gervasoni C, Vella A. A martial arts injury: karate induced unilateral haematoma of the adrenal gland. Br J Sports Med. 2006 Aug; 40(8):730-1; discussion 731. Epub 2006 May 24.
    View PubMed
  183. Morris GA, Lowe CE, Cooper JD, Payne F, Vella A, Godfrey L, Hulme JS, Walker NM, Healy BC, Lam AC, Lyons PA, Todd JA. Polymorphism discovery and association analyses of the interferon genes in type 1 diabetes. BMC Genet. 2006; 7:12. Epub 2006 Feb 22.
    View PubMed
  184. Smyth DJ, Howson JM, Payne F, Maier LM, Bailey R, Holland K, Lowe CE, Cooper JD, Hulme JS, Vella A, Dahlman I, Lam AC, Nutland S, Walker NM, Twells RC, Todd JA. Analysis of polymorphisms in 16 genes in type 1 diabetes that have been associated with other immune-mediated diseases. BMC Med Genet. 2006; 7:20. Epub 2006 Mar 06.
    View PubMed
  185. Vella A, Cooper JD, Lowe CE, Walker N, Nutland S, Widmer B, Jones R, Ring SM, McArdle W, Pembrey ME, Strachan DP, Dunger DB, Twells RC, Clayton DG, Todd JA. Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms. Am J Hum Genet. 2005 May; 76(5):773-9.
  186. Maier LM, Smyth DJ, Vella A, Payne F, Cooper JD, Pask R, Lowe C, Hulme J, Smink LJ, Fraser H, Moule C, Hunter KM, Chamberlain G, Walker N, Nutland S, Undlien DE, Ronningen KS, Guja C, Ionescu-Tirgoviste C, Savage DA, Strachan DP, Peterson LB, Todd JA, Wicker LS, Twells RC. Construction and analysis of tag single nucleotide polymorphism maps for six human-mouse orthologous candidate genes in type 1 diabetes. BMC Genet. 2005; 6(1):9. Epub 2005 Feb 18.
    View PubMed
  187. Vella A, Rizza RA. Extrapancreatic effects of GIP and GLP-1. Horm Metab Res. 2004 Nov-Dec; 36 (11-12):830-6
    View PubMed
  188. Smyth D, Cooper JD, Collins JE, Heward JM, Franklyn JA, Howson JM, Vella A, Nutland S, Rance HE, Maier L, Barratt BJ, Guja C, Ionescu-Tirgoviste C, Savage DA, Dunger DB, Widmer B, Strachan DP, Ring SM, Walker N, Clayton DG, Twells RC, Gough SC, Todd JA. Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus. Diabetes. 2004 Nov; 53(11):3020-3.
    View PubMed
  189. Vella A, Camilleri M, Rizza RA. The gastrointestinal tract and glucose tolerance. Curr Opin Clin Nutr Metab Care. 2004 Jul; 7 (4):479-84
    View PubMed
  190. Vella A, Howson JM, Barratt BJ, Twells RC, Rance HE, Nutland S, Tuomilehto-Wolf E, Tuomilehto J, Undlien DE, Ronningen KS, Guja C, Ionescu-Tirgoviste C, Savage DA, Todd JA. Lack of association of the Ala(45)Thr polymorphism and other common variants of the NeuroD gene with type 1 diabetes. Diabetes. 2004 Apr; 54(4):1158-61.
  191. Reed AS, Charkoudian N, Vella A, Shah P, Rizza RA, Joyner MJ. Forearm vascular control during acute hyperglycemia in healthy humans. Am J Physiol Endocrinol Metab. 2004 Mar; 286: (3)E472-80.
    View PubMed
  192. Eftychi C, Howson JM, Barratt BJ, Vella A, Payne F, Smyth DJ, Twells RC, Walker NM, Rance HE, Tuomilehto-Wolf E, Tuomilehto J, Undlien DE, Ronningen KS, Guja C, Ionescu-Tiirgoviste C, Savage DA, Todd JA. Analysis of the type 2 diabetes-associated single nucleotide polymorphisms in the genes IRS1, KCNJ11, and PPARG2 in type 1 diabetes. Diabetes. 2004 Mar; 53(3):870-3.
    View PubMed
  193. Adkins A, Basu R, Persson M, Dicke B, Shah P, Vella A, Schwenk WF, Schwenk WF, Rizza R. Higher insulin concentrations are required to suppress gluconeogenesis than glycogenolysis in nondiabetic humans. Diabetes. 2003 Sep; 52 (9):2213-20
    View PubMed
  194. Delgado-Aros S, Vella A, Camilleri M, Low PA, Burton DD, Thomforde GM, Stephens D. Effects of glucagon-like peptide-1 and feeding on gastric volumes in diabetes mellitus with cardio-vagal dysfunction. Neurogastroenterol Motil. 2003 Aug; 15 (4):435-43
    View PubMed
  195. Vella A, Reed AS, Charkoudian N, Shah P, Basu R, Basu A, Joyner MJ, Rizza RA. Glucose-induced suppression of endogenous glucose production: dynamic response to differing glucose profiles. Am J Physiol Endocrinol Metab. 2003 Jul; 285(1):E25-30. Epub 2003 Mar 11.
    View PubMed
  196. Vella A, Service FJ, O'Brien PC. Glucose counterregulatory hormones in the 72-hour fast. Endocr Pract. 2003 Mar-Apr; 9 (2):115-8
    View PubMed
  197. Basu R, Di Camillo B, Toffolo G, Basu A, Shah P, Vella A, Rizza R, Cobelli C. Use of a novel triple-tracer approach to assess postprandial glucose metabolism. Am J Physiol Endocrinol Metab. 2003 Jan; 284(1):E55-69.
    View PubMed
  198. Shah P, Vella A, Basu A, Basu R, Adkins A, Schwenk WF, Johnson CM, Schwenk WF, Johnson CM, Nair KS, Jensen MD, Rizza RA. Elevated free fatty acids impair glucose metabolism in women: decreased stimulation of muscle glucose uptake and suppression of splanchnic glucose production during combined hyperinsulinemia and hyperglycemia. Diabetes. 2003 Jan; 52 (1):38-42
    View PubMed
  199. Kurtkaya-Yapicier O, Scheithauer BW, Carney JA, Kovacs K, Horvath E, Stratakis CA, Vidal S, Vella A, Young WF, Atkinson JL, Lloyd RV, Kontogeorgos G. Pituitary adenoma in Carney complex: an immunohistochemical, ultrastructural, and immunoelectron microscopic study. Ultrastruct Pathol. 2002 Nov-Dec; 26(6):345-53.
    View PubMed
  200. Vella A, Shah P, Reed AS, Adkins AS, Basu R, Rizza RA. Lack of effect of exendin-4 and glucagon-like peptide-1-(7,36)-amide on insulin action in non-diabetic humans. Diabetologia. 2002 Oct; 45 (10):1410-5 Epub 2002 Sept 05
    View PubMed
  201. Charkoudian N, Vella A, Reed AS, Minson CT, Shah P, Rizza RA, Joyner MJ. Cutaneous vascular function during acute hyperglycemia in healthy young adults. J Appl Physiol (1985). 2002 Oct; 93(4):1243-50.
    View PubMed
  202. Vella A, Shah P, Basu R, Basu A, Camilleri M, Schwenk WF, Rizza RA. Effect of enteral vs. parenteral glucose delivery on initial splanchnic glucose uptake in nondiabetic humans. Am J Physiol Endocrinol Metab. 2002 Aug; 283(2):E259-66.
    View PubMed
  203. Vella A, Lee JS, Lee JS, Camilleri M, Szarka LA, Burton DD, Zinsmeister AR, Rizza RA, Klein PD. Effects of pramlintide, an amylin analogue, on gastric emptying in type 1 and 2 diabetes mellitus. Neurogastroenterol Motil. 2002 Apr; 14 (2):123-31
    View PubMed
  204. Delgado-Aros S, Kim DY, Burton DD, Thomforde GM, Stephens D, Brinkmann BH, Vella A, Camilleri M. Effect of GLP-1 on gastric volume, emptying, maximum volume ingested, and postprandial symptoms in humans. Am J Physiol Gastrointest Liver Physiol. 2002 Mar; 282 (3):G424-31
    View PubMed
  205. Shah P, Vella A, Basu A, Basu R, Adkins A, Schwenk WF, Johnson CM, Schwenk WF, Johnson CM, Nair KS, Jensen MD, Rizza RA. Effects of free fatty acids and glycerol on splanchnic glucose metabolism and insulin extraction in nondiabetic humans. Diabetes. 2002 Feb; 51 (2):301-10
    View PubMed
  206. Vella A, Pineda AA, O'Brien T. Low-density lipoprotein apheresis for the treatment of refractory hyperlipidemia. Mayo Clin Proc. 2001 Oct; 76 (10):1039-46
    View PubMed
  207. Vella A, Young WF. Pituitary apoplexy. Endocrinologist. 2001 Jul-Aug; 11(4):282-8.
  208. Vella A, Shah P, Basu R, Basu A, Camilleri M, Schwenk WF, Rizza RA. Type I diabetes mellitus does not alter initial splanchnic glucose extraction or hepatic UDP-glucose flux during enteral glucose administration. Diabetologia. 2001 Jun; 44(6):729-37.
    View PubMed
  209. Basu A, Basu R, Shah P, Vella A, Rizza RA, Jensen MD. Systemic and regional free fatty acid metabolism in type 2 diabetes. Am J Physiol Endocrinol Metab. 2001 Jun; 280 (6):E1000-6
    View PubMed
  210. Basu A, Basu R, Shah P, Vella A, Johnson CM, Jensen M, Johnson CM, Jensen M, Nair KS, Schwenk WF, Schwenk WF, Rizza RA. Type 2 diabetes impairs splanchnic uptake of glucose but does not alter intestinal glucose absorption during enteral glucose feeding: additional evidence for a defect in hepatic glucokinase activity. Diabetes. 2001 Jun; 50 (6):1351-62
    View PubMed
  211. Vella A, Thompson GB, Grant CS, van Heerden JA, Farley DR, Young WF Jr. Laparoscopic adrenalectomy for adrenocorticotropin-dependent Cushing's syndrome. J Clin Endocrinol Metab. 2001 Apr; 86(4):1596-9.
    View PubMed
  212. Vella A, Shah P, Basu R, Basu A, Camilleri M, Schwenk FW, Holst JJ, Rizza RA. Effect of glucagon-like peptide-1(7-36)-amide on initial splanchnic glucose uptake and insulin action in humans with type 1 diabetes. Diabetes. 2001 Mar; 50 (3):565-72
    View PubMed
  213. Vella A, Nippoldt TB, Morris JC 3rd. Adrenal hemorrhage: a 25-year experience at the Mayo Clinic. Mayo Clin Proc. 2001 Feb; 76 (2):161-8
    View PubMed
  214. Josifova D, Gatt G, Aquilina A, Serafimov V, Vella A, Felice A. Treatment of leg ulcers with platelet-derived wound healing factor (PDWHFS) in a patient with beta thalassaemia intermedia. Br J Haematol 2001 Feb; 112 (2):527-9
    View PubMed
  215. Shah P, Vella A, Basu A, Basu R, Schwenk WF, Rizza RA. Lack of suppression of glucagon contributes to postprandial hyperglycemia in subjects with type 2 diabetes mellitus. J Clin Endocrinol Metab. 2000 Nov; 85 (11):4053-9
    View PubMed
  216. Samsom M, Szarka LA, Camilleri M, Vella A, Zinsmeister AR, Rizza RA. Pramlintide, an amylin analog, selectively delays gastric emptying: potential role of vagal inhibition. Am J Physiol Gastrointest Liver Physiol. 2000 Jun; 278 (6):G946-51
    View PubMed
  217. Vella A, Shah P, Basu R, Basu A, Holst JJ, Rizza RA. Effect of glucagon-like peptide 1(7-36) amide on glucose effectiveness and insulin action in people with type 2 diabetes. Diabetes. 2000 Apr; 49 (4):611-7
    View PubMed
  218. Basu A, Basu R, Shah P, Vella A, Johnson CM, Johnson CM, Nair KS, Jensen MD, Schwenk WF, Schwenk WF, Rizza RA. Effects of type 2 diabetes on the ability of insulin and glucose to regulate splanchnic and muscle glucose metabolism: evidence for a defect in hepatic glucokinase activity. Diabetes. 2000 Feb; 49 (2):272-83
    View PubMed
  219. Vella A, Carlson LA, Blier B, Felty C, Kuiper JD, Rooke TW. Circulator boot therapy alters the natural history of ischemic limb ulceration. Vasc Med. 2000; 5(1):21-5.
    View PubMed
  220. Vella A, Gerber TC, Hayes DL, Reeder GS. Digoxin, hypercalcaemia, and cardiac conduction. Postgrad Med J. 1999 Sep; 75 (887):554-6
    View PubMed
  221. Vella A, McPhail I, Litin S. Unilateral proptosis in a 74-year-old woman. Adv Exp Med Biol. 1999; 455:529-33
    View PubMed
  222. Vella A, Farrugia G. D-lactic acidosis: pathologic consequence of saprophytism. Mayo Clin Proc. 1998 May; 73(5):451-6.
    View PubMed
  223. Vella A, McPhail IR, Litin SC. 74-year-old woman with cough and proptosis. Mayo Clin Proc. 1997 Jun; 72 (6):575-8
    View PubMed
  224. Vella A, Farrugia G. 90-year-old man with fever and melena (translated into Polish). Medycyna Prakyczna. 1997 May.
  225. Vella A, Farrugia G. 90-year-old man with fever and melena. Mayo Clin Proc. 1996 Dec; 71 (12):1205-8
    View PubMed
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