Adrian Vella, M.D.
Endocrinologist
Internist
Zeini M, Laurenti MC, Egan AM, Muthusamy K, Ramar A, Vella E, Bailey KR, Cobelli C, Dalla Man C,
Vella A
. The Longitudinal Effect of Diabetes-Associated Variation in TCF7L2 on Islet Function in Humans. Diabetes. 2024 Sep 1; 73 (9):1440-1446
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Dugani SB, Lahr BD, Xie H, Mielke MM, Bailey KR,
Vella A
. County Rurality and Incidence and Prevalence of Diagnosed Diabetes in the United States. Mayo Clin Proc. 2024 Jul; 99 (7):1078-1090 Epub 2024 Mar 19
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Vella M, Mohan S, Christie H, Bailey KR, Cobelli C, Dalla Man C, Matveyenko A, Egan AM,
Vella A
. Diabetes-associated Genetic Variation in MTNR1B and Its Effect on Islet Function. J Endocr Soc. 2024 Jul 1; 8 (8):bvae130 Epub 2024 July 09
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Tabatabaei Yeganeh HS, Kiliaki SA, Gnanapandithan K, Loor-Torres R, Duran M, Yousufuddin M, Prokop LJ,
Vella A
, Montori VM, Dugani SB. Inclusion of Rurality and Social Determinants of Health in Documents for the Primary Prevention of Type 2 Diabetes: A Systematic Review. Metab Syndr Relat Disord. 2024 Jun; 22 (5):315-326 Epub 2024 May 06
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Voigt JH, Lauritsen KM, Pedersen SB, Hansen TK, Moller N, Jessen N, Laurenti MC, Dalla Man C,
Vella A
, Gormsen LC, Sondergaard E. Four weeks SGLT2 inhibition improves beta cell function and glucose tolerance without affecting muscle free fatty acid or glucose uptake in subjects with type 2 diabetes. Basic Clin Pharmacol Toxicol. 2024 May; 134 (5):643-656 Epub 2024 Feb 26
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Pinto E Vairo F, Kemppainen JL, Vitek CRR, Whalen DA, Kolbert KJ, Sikkink KJ, Kroc SA, Kruisselbrink T, Shupe GF, Knudson AK, Burke EM, Loftus EC, Bandel LA, Prochnow CA, Mulvihill LA, Thomas B, Gable DM, Graddy CB, Garzon GGM, Ekpoh IU, Porquera EMC, Fervenza FC, Hogan MC, El Ters M, Warrington KJ, Davis JM 3rd, Koster MJ, Orandi AB, Basiaga ML,
Vella A
, Kumar S, Creo AL, Lteif AN, Pittock ST, Tebben PJ, Abate EG, Joshi AY, Ristagno EH, Patnaik MS, Schimmenti LA, Dhamija R, Sabrowsky SM, Wierenga KJ, Keddis MT, Samadder NJJ, Presutti RJ, Robinson SI, Stephens MC, Roberts LR, Faubion WA Jr, Driscoll SW, Wong-Kisiel LC, Selcen D, Flanagan EP, Ramanan VK, Jackson LM, Mauermann ML, Ortega VE, Anderson SA, Aoudia SL, Klee EW, McAllister TM, Lazaridis KN. Correction: Implementation of genomic medicine for rare disease in a tertiary healthcare system: Mayo Clinic Program for Rare and Undiagnosed Diseases (PRaUD). J Transl Med. 2024 Apr 30; 22 (1):400
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Das D, Christie HE, Hegazi M, Takawy M, Pone KA,
Vella A
, Egan AM. Twin Pregnancy Complicated by Gestational Diabetes Mellitus: Maternal and Neonatal Outcomes. J Endocr Soc. 2024 Apr 6; 8 (6):bvae075 Epub 2024 Apr 16
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Karakaplan ND, Song Y, Laurenti MC,
Vella A
, Jensen MD. Suppression of Endogenous Insulin Secretion by Euglycemic Hyperinsulinemia. J Clin Endocrinol Metab. 2024 Jan 18; 109 (2):e596-e601
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Zhang L,
Vella A
, Nair KS, Jensen MD. Characteristics of Normal Weight Insulin-Resistant Adults with Unfavorable Health Outcomes. Metab Syndr Relat Disord. 2024 Jan 16 [Epub ahead of print]
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Kahn SE, Anderson CAM, Buse JB, Selvin E, Angell SY, Aroda VR, Cheng AYY, Danne T, Echouffo-Tcheugui JB, Fitzpatrick SL, Gadgil MD, Gastaldelli A, Gloyn AL, Green JB, Jastreboff AM, Kanaya AM, Kandula NR, Kovesdy CP, Laiteerapong N, Nadeau KJ, Pettus J, Pop-Busui R, Posey JE, Powe CE, Rebholz CM, Rickels MR, Sattar N, Shaw JE, Sims EK, Utzschneider KM,
Vella A
, Zhang C. Reflecting on a Year at the Helm of Diabetes Care. Diabetes Care 2024 Jan 1; 47 (1):4-6
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Sada A, Ramachandran D, Oberoi M, Habermann EB, Lyden ML, Dy BM, Foster TR, Halfdanarson TR, Levy MJ,
Vella A
, McKenzie TJ. Ethanol Ablation for Benign Insulinoma: Intraoperative and Endoscopic Approaches. J Surg Res. 2024 Jan; 293:663-669 Epub 2023 Oct 13
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De Leon DD, Arnoux JB, Banerjee I, Bergada I, Bhatti T, Conwell LS, Fu J, Flanagan SE, Gillis D, Meissner T, Mohnike K, Pasquini TLS, Shah P, Stanley CA,
Vella A
, Yorifuji T, Thornton PS. International Guidelines for the Diagnosis and Management of Hyperinsulinism. Horm Res Paediatr. 2024; 97 (3):279-298 Epub 2023 July 14
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Welch AA, Farahani RA, Egan AM, Laurenti MC, Zeini M, Vella M, Bailey KR, Cobelli C, Dalla Man C, Matveyenko A,
Vella A
. Glucagon-like peptide-1 receptor blockade impairs islet secretion and glucose metabolism in humans. J Clin Invest. 2023 Nov 15; 133 (22)
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Faggionato E, Laurenti MC,
Vella A
, Dalla Man C. Nonlinear mixed effects modeling of glucagon kinetics in healthy subjects. IEEE Transactions on Biomedical Engineering. 2023 Sep; 70 (9):2733-40
Schembri Wismayer D, Laurenti MC, Song Y, Egan AM, Welch AA, Bailey KR, Cobelli C, Dalla Man C, Jensen MD,
Vella A
. Effects of acute changes in fasting glucose and free fatty acid concentrations on indices of beta-cell function and glucose metabolism in subjects without diabetes. Am J Physiol Endocrinol Metab. 2023 Aug 1; 325 (2):E119-E131 Epub 2023 June 07
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Pinto E Vairo F, Kemppainen JL, Vitek CRR, Whalen DA, Kolbert KJ, Sikkink KJ, Kroc SA, Kruisselbrink T, Shupe GF, Knudson AK, Burke EM, Loftus EC, Bandel LA, Prochnow CA, Mulvihill LA, Thomas B, Gable DM, Graddy CB, Garzon GGM, Ekpoh IU, Porquera EMC, Fervenza FC, Hogan MC, El Ters M, Warrington KJ, Davis JM 3rd, Koster MJ, Orandi AB, Basiaga ML,
Vella A
, Kumar S, Creo AL, Lteif AN, Pittock ST, Tebben PJ, Abate EG, Joshi AY, Ristagno EH, Patnaik MS, Schimmenti LA, Dhamija R, Sabrowsky SM, Wierenga KJ, Keddis MT, Samadder NJJ, Presutti RJ, Robinson SI, Stephens MC, Roberts LR, Faubion WA Jr, Driscoll SW, Wong-Kisiel LC, Selcen D, Flanagan EP, Ramanan VK, Jackson LM, Mauermann ML, Ortega VE, Anderson SA, Aoudia SL, Klee EW, McAllister TM, Lazaridis KN. Implementation of genomic medicine for rare disease in a tertiary healthcare system: Mayo Clinic Program for Rare and Undiagnosed Diseases (PRaUD). J Transl Med. 2023 Jun 23; 21(1):410.
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Bielinski SJ, Yanes Cardozo LL, Takahashi PY, Larson NB, Castillo A, Podwika A, De Filippis E, Hernandez V, Mahajan GJ, Gonzalez C, Shubhangi Shubhangi, Decker PA, Killian JM, Olson JE, St Sauver JL, Shah P,
Vella A
, Ryu E, Liu H, Marshall GD, Cerhan JR, Singh D, Summers RL. Predictors of Metformin Failure: Repurposing Electronic Health Record Data to Identify High-Risk Patients. J Clin Endocrinol Metab. 2023 Jun 16; 108 (7):1740-1746
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Moazzami, Venkatesan, Rajagopalan, Vella, Egan. Gestational Diabetes Mellitus (GDM)—Outcomes for Normal-Weight Individuals Diabetes. 2023.
Sada A, McKenzie TJ,
Vella A
, Levy MJ, Halfdanarson TR. Interventional vs surgical procedures in localized/nonmetastatic insulinomas (ablation vs surgery). Endocr Relat Cancer. 2023 Jun 1; 30 (6) Epub 2023 May 02
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Farahani RA, Egan AM, Welch AA, Laurenti MC, Cobelli C, Dalla Man C,
Vella A
. The Effect of Glucagon-Like Peptide 1 Receptor Blockade on Glucagon-Induced Stimulation of Insulin Secretion. Diabetes. 2023 Apr 1; 72 (4):449-454
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Kahn SE, Anderson CAM, Buse JB, Selvin E, Angell SY, Aroda VR, Castle JR, Cheng AYY, Danne T, Echouffo-Tcheugui JB, Florez JC, Gadgil MD, Gastaldelli A, Green JB, Jastreboff AM, Kanaya AM, Kandula NR, Kovesdy CP, Laiteerapong N, Nadeau KJ, Pop-Busui R, Powe CE, Rebholz CM, Rickels MR, Sattar N, Shaw JE, Sims EK, Utzschneider KM,
Vella A
, Zhang C. "The Times They Are A-Changin'" at Diabetes Care. Diabetes Care 2023 Jan 1; 46 (1):3-5
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Schembri Wismayer D, Laurenti MC, Song Y, Egan AM, Welch AA, Bailey KR, Cobelli C, Dalla Man C, Jensen MD,
Vella A
. Effects of acute changes in fasting glucose and free fatty acid concentrations on indices of beta-cell function and glucose metabolism in subjects without diabetes. American Journal of Physiology. Endocrinology and Metabolism. 2023; 325 (2):E119-31
Tabatabaei Yeganeh HS, Prokop LJ, Kiliaki SA, Gnanapandithan K, Yousufuddin M,
Vella A
, Montori VM, Dugani SB. Guidelines, position statements, and advisories for the primary prevention of type 2 diabetes, hypertension, and cardiovascular disease in rural populations: A systematic review protocol. PLoS One. 2023; 18 (6):e0288116 Epub 2023 June 29
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Kohlenberg JD, Laurenti MC, Egan AM, Wismayer DS, Bailey KR, Cobelli C, Man CD,
Vella A
. Differential contribution of alpha and beta cell dysfunction to impaired fasting glucose and impaired glucose tolerance. Diabetologia. 2023 Jan; 66 (1):201-212 Epub 2022 Sept 16
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Sada A, Habermann EB, Szabo Yamashita T, Thompson GB, Lyden ML, Foster TR, Dy BM, Halfdanarson TR,
Vella A
, McKenzie TJ. Comparison Between Sporadic and Multiple Endocrine Neoplasia Type 1-Associated Insulinoma. J Am Coll Surg. 2022 Nov 1; 235 (5):756-763 Epub 2022 Oct 17
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Egan AM, Galior KD, Maus AD, Fatica E, Simha V, Shah P, Singh RJ,
Vella A
. Pitfalls in Diagnosing Hypoglycemia Due to Exogenous Insulin: Validation and Utility of an Insulin Analog Assay. Mayo Clin Proc. 2022 Nov; 97 (11):1994-2004 Epub 2022 Oct 07
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Blonde L, Umpierrez GE, Reddy SS, McGill JB, Berga SL, Bush M, Chandrasekaran S, DeFronzo RA, Einhorn D, Galindo RJ, Gardner TW, Garg R, Garvey WT, Hirsch IB, Hurley DL, Izuora K, Kosiborod M, Olson D, Patel SB, Pop-Busui R, Sadhu AR, Samson SL, Stec C, Tamborlane WV Jr, Tuttle KR, Twining C,
Vella A
, Vellanki P, Weber SL. American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update. Endocr Pract. 2022 Oct; 28 (10):923-1049 Epub 2022 Aug 11
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Dugani SB, Wood-Wentz CM, Mielke MM, Bailey KR,
Vella A
. Assessment of Disparities in Diabetes Mortality in Adults in US Rural vs Nonrural Counties, 1999-2018. JAMA Netw Open. 2022 Sep 1; 5 (9):e2232318 Epub 2022 Sept 01
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Maselli D, Atieh J, Clark MM, Eckert D, Taylor A, Carlson P, Burton DD, Busciglio I, Harmsen WS,
Vella A
, Acosta A, Camilleri M. Effects of liraglutide on gastrointestinal functions and weight in obesity: A randomized clinical and pharmacogenomic trial. Obesity (Silver Spring). 2022 Aug; 30 (8):1608-1620
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Adams JD, Egan AM, Laurenti MC, Schembri Wismayer D, Bailey KR, Cobelli C, Dalla Man C,
Vella A
. The Effect of Diabetes-Associated Variation in TCF7L2 on Postprandial Glucose Metabolism When Glucagon and Insulin Concentrations Are Matched. Metab Syndr Relat Disord. 2022 Aug; 20 (6):329-335 Epub 2022 Apr 18
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James H, Gonsalves WI, Manjunatha S, Dasari S, Lanza IR, Klaus KA,
Vella A
, Andrews JC, Nair KS. The Effect of Glucagon on Protein Catabolism During Insulin Deficiency: Exchange of Amino Acids Across Skeletal Muscle and the Splanchnic Bed. Diabetes. 2022 Aug 1; 71 (8):1636-1648
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Riddle MC, Bakris G, Blonde L, Boulton AJM, Castle J, DiMeglio L, Gonder-Frederick L, Hu F, Kahn S, Kaul S, Moses R, Rich S, Rosenstock J, Selvin E,
Vella A
, Wylie-Rosett J, with and on behalf of Associate Editors Vanita Aroda. Editorial Cycles and Continuity of Diabetes Care. Diabetes Care 2022 Jul 7; 45 (7):1493-1494
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Egan AM,
Vella A
. Tighten Your Belt! Banded Roux-en-Y Gastric Bypass for Diabetes Remission? Diabetes Care. 2022 Jul 7; 45 (7):1495-1497
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Laurenti MC, Arora P, Dalla Man C, Andrews JC, Rizza RA, Matveyenko A, Bailey KR, Cobelli C,
Vella A
. The relationship between insulin and glucagon concentrations in non-diabetic humans. Physiol Rep. 2022 Jul; 10 (13):e15380
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Ebert SM, Rasmussen BB, Judge AR, Judge SM, Larsson L, Wek RC, Anthony TG, Marcotte GR, Miller MJ, Yorek MA,
Vella A
, Volpi E, Stern JI, Strub MD, Ryan Z, Talley JJ, Adams CM. Biology of Activating Transcription Factor 4 (ATF4) and Its Role in Skeletal Muscle Atrophy. J Nutr. 2022 Apr 1; 152 (4):926-938
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Ebert SM, Rasmussen BB, Judge AR, Judge SM, Larsson L, Wek RC, Anthony TG, Marcotte GR, Miller MJ, Yorek MA,
Vella A
, Volpi E, Stern JI, Strub MD, Ryan Z, Talley JJ, Adams CM. Biology of Activating Transcription Factor 4 (ATF4) and Its Role in Skeletal Muscle Atrophy. J Nutr. 2022 Apr; 152 (4):926-938 Epub 2023 Feb 18
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Camilleri M,
Vella A
. What to do about the leaky gut. Gut. 2022 Feb; 71 (2):424-435 Epub 2021 Sept 11
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Linch F, Thompson S, Fleming C,
Vella A
, Andrews J. Hepatic Artery Embolization for Palliation of Symptomatic Hypoglycemia in Patients With Hepatic Insulinoma Metastases. J Endocr Soc. 2021 Dec 1; 5 (12):bvab149 Epub 2021 Oct 07
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Adams JD, Egan AM, Laurenti MC, Schembri Wismayer D, Bailey KR, Cobelli C, Dalla Man C,
Vella A
. Insulin secretion and action and the response of endogenous glucose production to a lack of glucagon suppression in nondiabetic subjects. Am J Physiol Endocrinol Metab. 2021 Nov 1; 321 (5):E728-E736 Epub 2021 Oct 18
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Dugani SB, Christenson LR, Aakre JA, Bui HH,
Vella A
, Mielke MM. Association of plasma ceramides with prevalent and incident type 2 diabetes mellitus in middle and older aged adults. Diabetes Res Clin Pract. 2021 Sep; 179:108991 Epub 2021 July 29
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Javeed N, Her TK, Brown MR, Vanderboom P, Rakshit K, Egan AM,
Vella A
, Lanza I, Matveyenko AV. Pro-inflammatory beta cell small extracellular vesicles induce beta cell failure through activation of the CXCL10/CXCR3 axis in diabetes. Cell Rep. 2021 Aug 24; 36 (8):109613
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Dugani SB, Mielke MM,
Vella A
. Burden and management of type 2 diabetes in rural United States. Diabetes Metab Res Rev. 2021 Jul; 37 (5):e3410 Epub 2020 Oct 05
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Kunz HE, Hart CR, Gries KJ, Parvizi M, Laurenti M, Dalla Man C, Moore N, Zhang X, Ryan Z, Polley EC, Jensen MD,
Vella A
, Lanza IR. Adipose tissue macrophage populations and inflammation are associated with systemic inflammation and insulin resistance in obesity. Am J Physiol Endocrinol Metab. 2021 Jul 1; 321 (1):E105-E121 Epub 2021 May 17
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Laurenti MC, Matveyenko A,
Vella A
. Measurement of Pulsatile Insulin Secretion: Rationale and Methodology. Metabolites. 2021 Jun 22; 11 (7) Epub 2021 June 22
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Egan AM, Laurenti MC, Hurtado Andrade MD, Dalla Man C, Cobelli C, Bailey KR,
Vella A
. Limitations of the fasting proinsulin to insulin ratio as a measure of beta-cell health in people with and without impaired glucose tolerance. Eur J Clin Invest. 2021 Jun; 51 (6):e13469 Epub 2020 Dec 16
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Laurenti MC, Dalla Man C, Varghese RT, Andrews JC, Jones JG, Barosa C, Rizza RA, Matveyenko A, De Nicolao G, Bailey KR, Cobelli C,
Vella A
. Insulin Pulse Characteristics and Insulin Action in Non-diabetic Humans. J Clin Endocrinol Metab. 2021 May 13; 106 (6):1702-1709
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Dugani SB, Girardo ME, De Filippis E, Mielke MM,
Vella A
. Risk Factors and Wellness Measures Associated with Prediabetes and Newly Diagnosed Type 2 Diabetes Mellitus in Hispanic Adults. Metab Syndr Relat Disord. 2021 Apr; 19 (3):180-189 Epub 2021 Jan 15
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Sada A, Yamashita TS, Glasgow AE, Habermann EB, Thompson GB, Lyden ML, Dy BM, Halfdanarson TR,
Vella A
, McKenzie TJ. Comparison of benign and malignant insulinoma. Am J Surg. 2021 Feb; 221 (2):437-447 Epub 2020 Aug 16
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Laurenti MC,
Vella A
, Adams JD, Schembri Wismayer DJ, Egan AM, Dalla Man C. Assessment of individual and standardized glucagon kinetics in healthy humans. Am J Physiol Endocrinol Metab. 2021 Jan 1; 320 (1):E71-E77 Epub 2020 Nov 02
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Egan AM, Dow ML,
Vella A
. A Review of the Pathophysiology and Management of Diabetes in Pregnancy. Mayo Clin Proc. 2020 Dec; 95 (12):2734-2746 Epub 2020 July 28
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Kittah E, Camilleri M, Jensen MD,
Vella A
. A Pilot Study Examining the Effects of GLP-1 Receptor Blockade Using Exendin-(9,39) on Gastric Emptying and Caloric Intake in Subjects With and Without Bariatric Surgery. Metab Syndr Relat Disord. 2020 Nov; 18 (9):406-412 Epub 2020 Aug 20
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Samakkarnthai P, Sfeir JG, Atkinson EJ, Achenbach SJ, Wennberg PW, Dyck PJ, Tweed AJ, Volkman TL, Amin S, Farr JN,
Vella A
, Drake MT, Khosla S. Determinants of Bone Material Strength and Cortical Porosity in Patients with Type 2 Diabetes Mellitus. J Clin Endocrinol Metab. 2020 Oct 1; 105 (10):e3718-29
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Vargas EJ, Abu Dayyeh BK, Storm AC, Bazerbachi F, Matar R,
Vella A
, Kellogg T, Stier C. Endoscopic management of dumping syndrome after Roux-en-Y gastric bypass: a large international series and proposed management strategy. Gastrointest Endosc. 2020 Jul; 92 (1):91-96 Epub 2020 Feb 26
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Sada A, Glasgow AE,
Vella A
, Thompson GB, McKenzie TJ, Habermann EB. Malignant Insulinoma: A Rare Form of Neuroendocrine Tumor. World J Surg. 2020 Jul; 44 (7):2288-2294
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Egan AM,
Vella A
. Endoscopic Treatments for Obesity: The Good, the Bad, and the Ugly. Endocrinol Metab Clin North Am. 2020 Jun; 49 (2):315-328 Epub 2020 Apr 11
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Sharma A,
Vella A
. Glucose metabolism in Cushing's syndrome. Curr Opin Endocrinol Diabetes Obes. 2020 Jun; 27 (3):140-145
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Eckhardt BA, Rowsey JL, Thicke BS, Fraser DG, O'Grady KL, Bondar OP, Hines JM, Singh RJ, Thoreson AR, Rakshit K, Lagnado AB, Passos JF,
Vella A
, Matveyenko AV, Khosla S, Monroe DG, Farr JN. Accelerated osteocyte senescence and skeletal fragility in mice with type 2 diabetes. JCI Insight. 2020 May 7; 5 (9) Epub 2020 May 07
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Calderon G, McRae A, Rievaj J, Davis J, Zandvakili I, Linker-Nord S, Burton D, Roberts G, Reimann F, Gedulin B,
Vella A
, LaRusso NF, Camilleri M, Gribble FM, Acosta A. Ileo-colonic delivery of conjugated bile acids improves glucose homeostasis via colonic GLP-1-producing enteroendocrine cells in human obesity and diabetes. EBioMedicine. 2020 May; 55:102759 Epub 2020 Apr 25
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Kadouh H, Chedid V, Halawi H, Burton DD, Clark MM, Khemani D,
Vella A
, Acosta A, Camilleri M. GLP-1 Analog Modulates Appetite, Taste Preference, Gut Hormones, and Regional Body Fat Stores in Adults with Obesity. J Clin Endocrinol Metab. 2020 May 1; 105 (5)
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Laurenti MC, Dalla Man C, Varghese RT, Andrews JC, Rizza RA, Matveyenko A, De Nicolao G, Cobelli C,
Vella A
. Diabetes-associated genetic variation in TCF7L2 alters pulsatile insulin secretion in humans. JCI Insight. 2020 Apr 9; 5 (7) Epub 2020 Apr 09
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Adams JD, Dalla Man C, Laurenti MC, Andrade MDH, Cobelli C, Rizza RA, Bailey KR,
Vella A
. Fasting glucagon concentrations are associated with longitudinal decline of beta-cell function in non-diabetic humans. Metabolism. 2020 Apr; 105:154175 Epub 2020 Feb 08
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Mishra R, Akerlund M, Cousminer DL, Ahlqvist E, Bradfield JP, Chesi A, Hodge KM, Guy VC, Brillon DJ, Pratley RE, Rickels MR,
Vella A
, Ovalle F, Harris RI, Melander O, Varvel S, Hakonarson H, Froguel P, Lonsdale JT, Mauricio D, Schloot NC, Khunti K, Greenbaum CJ, Yderstraede KB, Tuomi T, Voight BF, Schwartz S, Boehm BO, Groop L, Leslie RD, Grant SFA. Genetic Discrimination Between LADA and Childhood-Onset Type 1 Diabetes Within the MHC. Diabetes Care. 2020 Feb; 43 (2):418-425 Epub 2019 Dec 16
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Weivoda MM, Chew CK, Monroe DG, Farr JN, Atkinson EJ, Geske JR, Eckhardt B, Thicke B, Ruan M, Tweed AJ, McCready LK, Rizza RA, Matveyenko A, Kassem M, Andersen TL,
Vella A
, Drake MT, Clarke BL, Oursler MJ, Khosla S. Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism. Nat Commun. 2020 Jan 7; 11 (1):87 Epub 2020 Jan 07
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Laurenti MC, Man CD, Varghese RT, Andrews JC, Rizza RA, Matveyenko A, De Nicolao G, Cobelli C,
Vella A
. Intrahepatic heteropolymerization of M and Z alpha-1-antitrypsin JCI Insight. 2020; 5 (14):e136136
Anderson B, Carlson P, Laurenti M,
Vella A
, Camilleri M, Desai A, Feuerhak K, Bharucha AE. Association between allelic variants in the glucagon-like peptide 1 and cholecystokinin receptor genes with gastric emptying and glucose tolerance. Neurogastroenterol Motil. 2020 Jan; 32 (1):e13724 Epub 2019 Nov 05
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Smushkin G, Sathananthan A, Man CD, Camilleri M, Cobelli C, Rizza RA,
Vella A
. Letter to the Editor: "Defects in GLP-1 Response to an Oral Challenge Do Not Play a Significant Role in the Pathogenesis of Prediabetes". J Clin Endocrinol Metab 2019 Nov 1; 104 (11):5106-5107
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Egan A,
Vella A
. TTP399: an investigational liver-selective glucokinase (GK) activator as a potential treatment for type 2 diabetes. Expert Opin Investig Drugs. 2019 Sep; 28 (9):741-747 Epub 2019 Aug 16
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Laurenti MC,
Vella A
, Varghese RT, Andrews JC, Sharma A, Kittah NE, Rizza RA, Matveyenko A, De Nicolao G, Cobelli C, Dalla Man C. Assessment of pulsatile insulin secretion derived from peripheral plasma C-peptide concentrations by nonparametric stochastic deconvolution. Am J Physiol Endocrinol Metab. 2019 May 1; 316 (5):E687-E694 Epub 2019 Feb 26
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Andrews KL, Dyck PJ, Kavros SJ,
Vella A
, Kazamel M, Clark V, Litchy WJ, Dyck PJB, Lodermeier KA, Davies JL, Carter RE, Klein CJ. Plantar Ulcers and Neuropathic Arthropathies: Associated Diseases, Polyneuropathy Correlates, and Risk Covariates. Adv Skin Wound Care. 2019 Apr; 32 (4):168-175
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Shah M, Laurenti MC, Dalla Man C, Ma J, Cobelli C, Rizza RA,
Vella A
. Contribution of endogenous glucagon-like peptide-1 to changes in glucose metabolism and islet function in people with type 2 diabetes four weeks after Roux-en-Y gastric bypass (RYGB). Metabolism. 2019 Apr; 93:10-17 Epub 2018 Dec 23
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Sara JD, Taher R, Kolluri N,
Vella A
, Lerman LO, Lerman A. Coronary microvascular dysfunction is associated with poor glycemic control amongst female diabetics with chest pain and non-obstructive coronary artery disease. Cardiovasc Diabetol. 2019 Feb 28; 18 (1):22
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Vella A
, Freeman JLR, Dunn I, Keller K, Buse JB, Valcarce C. Targeting hepatic glucokinase to treat diabetes with TTP399, a hepatoselective glucokinase activator. Sci Transl Med. 2019 Jan 16; 11 (475)
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Hurtado MD,
Vella A
. What is type 2 diabetes? Medicine (United Kingdom). 2019; 47 (1):10-5
Adams JD, Treiber G, Hurtado MD, Laurenti MC, Dalla Man C, Cobelli C, Rizza RA,
Vella A
. Increased Rates of Meal Absorption Do Not Explain Elevated 1-Hour Glucose in Subjects With Normal Glucose Tolerance. J Endocr Soc. 2019 Jan 1; 3 (1):135-145 Epub 2018 Nov 21
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Cousminer DL, Ahlqvist E, Mishra R, Andersen MK, Chesi A, Hawa MI, Davis A, Hodge KM, Bradfield JP, Zhou K, Guy VC, Akerlund M, Wod M, Fritsche LG, Vestergaard H, Snyder J, Hojlund K, Linneberg A, Karajamaki A, Brandslund I, Kim CE, Witte D, Sorgjerd EP, Brillon DJ, Pedersen O, Beck-Nielsen H, Grarup N, Pratley RE, Rickels MR,
Vella A
, Ovalle F, Melander O, Harris RI, Varvel S, Grill VER, Hakonarson H, Froguel P, Lonsdale JT, Mauricio D, Schloot NC, Khunti K, Greenbaum CJ, Asvold BO, Yderstraede KB, Pearson ER, Schwartz S, Voight BF, Hansen T, Tuomi T, Boehm BO, Groop L, Leslie RD, Grant SFA, Bone Mineral Density in Childhood Study. First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes. Diabetes Care. 2018 Nov; 41 (11):2396-2403 Epub 2018 Sept 25
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Ruetten H, Gebauer M, Raymond RH, Calle RA, Cobelli C, Ghosh A, Robertson RP, Shankar SS, Staten MA, Stefanovski D,
Vella A
, Wright K, Fryburg DA, Foundation for the NIH Biomarkers Consortium Beta Cell Project Team. Mixed Meal and Intravenous L-Arginine Tests Both Stimulate Incretin Release Across Glucose Tolerance in Man: Lack of Correlation with beta Cell Function. Metab Syndr Relat Disord. 2018 Oct; 16 (8):406-415 Epub 2018 Aug 17
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Moran A, Toffolo G, Schiavon M,
Vella A
, Klaus K, Cobelli C, Nair KS. A novel triple-tracer approach to assess postprandial protein turnover. Am J Physiol Endocrinol Metab. 2018 Oct 01; 315(4):E469-E477. Epub 2018 Jun 05.
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Adams JD,
Vella A
. What Can Diabetes-Associated Genetic Variation in TCF7L2 Teach Us About the Pathogenesis of Type 2 Diabetes? Metab Syndr Relat Disord. 2018 Oct; 16 (8):383-389 Epub 2018 July 11
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