Drug information provided by: Merative, Micromedex®
The effects of the opioid medicine may last longer than the effects of the nalmefene. This means the breathing problems could come back. Always call for emergency help after the first dose of nalmefene.
Severe opioid withdrawal symptoms may happen suddenly after receiving this medicine. These include fast heartbeat, death, and increased blood pressure.
This medicine may cause heart or blood vessel problems (eg, pulmonary edema, tachycardia, ventricular fibrillation, high or low blood pressure). Check with your doctor right away if you have blue lips and fingernails, chest pain, coughing that sometimes produces a pink frothy sputum, difficulty, fast, or noisy breathing, fast heartbeat, fainting, increased sweating, trouble breathing, swelling in the legs and ankles, or unusual tiredness or weakness.
Nalmefene injection may not be able to completely reverse the opioid effects (eg, respiratory depression) of buprenorphine.
Portions of this document last updated: Feb. 01, 2024
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