胆碱 C-11 PET 扫描

概述

胆碱 C-11 PET 扫描是一种影像学检查，用于检测在治疗后复发的前列腺癌部位（复发性前列腺癌）。它可以在其他影像学检查没有帮助时使用。

胆碱 C-11 PET 扫描是一种正电子发射断层成像扫描，使用一种叫做胆碱 C-11 注射液的特殊化学示踪剂。通常同时进行低剂量计算机断层成像（CT）扫描，帮助进一步显示内部解剖结构。

胆碱 C-11 PET 扫描可以帮助医生发现更传统的影像学检查无法识别的前列腺癌可能复发的部位。尽早确定复发性前列腺癌的部位可让医生确定前列腺内部和外部微小、孤立的癌症沉积物，从而更有效地进行有针对性的治疗。

胆碱 C-11 PET 扫描使用一种放射性形式的维生素胆碱。在扫描完成之前，医生会将少量的示踪剂注射到手臂的静脉中。体内的前列腺癌细胞很容易吸收这种示踪剂。这可以帮助医生检查全身的前列腺癌细胞分布区域。然后医生将进行活检，取出一些细胞进行化验，以确认是否存在复发性前列腺癌。

目的

A choline C-11 PET scan looks for cancer cells and other fast-growing cells in the body. Most often, it's done to find prostate cancer that comes back after treatment, which is sometimes called recurrent prostate cancer. A choline C-11 PET scan might be used if other imaging tests haven't been helpful in finding the cancer.

Researchers also are studying other ways to use choline C-11 PET scans. This test has shown promise in finding overactive parathyroid glands. Parathyroid glands are found behind the thyroid at the bottom of the neck. They make parathyroid hormone, which helps keep the right balance of calcium in the body. Sometimes one or more of the glands make too much parathyroid hormone. This condition is called hyperparathyroidism. Studies show that choline C-11 PET scans might help find overactive parathyroid glands when other imaging tests can't.

风险

A choline C-11 PET scan is a safe imaging test. Like all tests, it has some risks. These include:

• A mild reaction at the place where the radioactive tracer goes into the arm.
• Allergic reaction to the radioactive tracer.
• Exposure to radiation from the tracer.
• False-negative result. This can happen if cancer is present but the test doesn't detect it.
• False-positive result. This can happen if the scan detects something that looks like cancer, but further testing finds that it isn't cancer.

如何进行准备

If your healthcare team gives you instructions to help you prepare for a choline C-11 PET scan, follow them carefully. You may be asked to:

• Stop eating for a few hours before the test.
• Drink plenty of liquids, such as water, for a few hours before the test.

可能出现的情况

During a choline C-11 PET scan, you receive an injection in your arm and then have an imaging test.

A healthcare professional injects a radioactive tracer into a vein in your arm. The tracer is a radioactive form of the vitamin choline.

After the injection, you'll have a positron emission tomography scan, also called a PET scan. During the scan you lie on a table. The table slowly moves into the center of the imaging machine. The machine takes images of the body.

Often the same machine does a CT scan at the same time. Sometimes a choline C-11 PET scan is done by a machine that also makes MRI pictures.

Once the imaging tests are complete, you can go about your day. Your healthcare team might recommend that you empty your bladder as soon as you can after the test. This helps clear the radioactive tracer from the body.

结果

Ask your healthcare team when you can expect to know the results of your choline C-11 PET scan. This imaging test shows places in the body that absorb the radioactive tracer. Places that absorb the tracer may be cancer or another condition that causes cells to grow quickly. Sometimes other imaging tests or procedures might be needed to be sure.