Clinical Trials 下面列出了当前开展的临床试验。135 研究 Neurology and Neurosurgery (仅限开放研究). 根据地点、状态和其他条件对此研究列表进行过滤。 A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT Rochester, Minn. The purpose of this study is to monitor outcome to ensure that children and young adults with localized central nervous system (CNS) non-germinomatous germ cell tumors (NGGCT) treated with Induction chemotherapy followed by response evaluation and whole ventricular + spinal canal irradiation (WVSCI) will maintain the excellent 2-year progression free survival (PFS) rate as compared to ACNS0122. Also, to improve disease control by decreasing the number of spinal relapses for patients who achieve a complete response (CR) or partial response (PR) and receive WVSCI as compared to whole ventricular radiation on ACNS1123. Resting State Connectivity in Adolescents with Postural Orthostatic Tachycardia Syndrome and Chronic Pain Rochester, Minn. The purposes of this study are to compare the functional connectivity in adolescent patients with Postural Orthostatic Tachycardia Syndrome (POTS) both with and without chronic pain, to those with chronic pain alone, to that of healthy controls; to evaluate whether there is a change in functional connectivity following participation in an intensive rehabilitation-oriented program previously demonstrated to have excellent outcomes with regard to functional recovery and symptom control; and to correlate outcomes using standardized symptom and function rating scales to imaging findings. Creation of PLACENTA/Serum Repository Database: Autoimmunity from Mother To Baby Study Rochester, Minn. The purpose of the study is to learn more about autoimmunity and potential mother to baby transmission of pathogenic antibodies. The collected research samples from children will be frozen and stored at the Mayo Clinic and will be used for future studies of autoimmune diseases. A Prospective Registry for Patients with REM Sleep Behavior Disorder and Polysomnographic REM Sleep without Atonia and Controls Rochester, Minn. The purpose of this study is to follow patients with REM sleep behavior disorder (RBD) over time and learn which types of RBD patients may be at risk of developing other diseases. Cerebrospinal Fluid (CSF) Biomarkers for Prediction of Dementia Rochester, Minn., Jacksonville, Fla. To further investigate biomarkers in CSF as possible predictors for mild cognitive impairment and dementia A Study to Assess Hyperphosphorylated Tau PET Binding in Primary Progressive Aphasia Rochester, Minn. This study is designed to learn more about the use of a new imaging agent AV-1451 which shows strong binding to abmormal tau in the brain, to see if it will allow positron emission tomography (PET) scanning of tau in the brains of patients with Primary Progressive Aphasia. Pre-operative vs. Post-operative Radiosurgery for Metastatic Brain Tumors Rochester, Minn., Jacksonville, Fla., Scottsdale/Phoenix, Ariz. The purpose of this study is to determine whether there is an increase in the time of a first occurrence of either: local recurrence, leptomeningeal disease, or symptomatic radiation brain necrosis in patients with brain metastases who receive SRS prior to surgery as compared to patients who receive surgery prior to SRS. Long-Term Observational Extension of Participants in CREST-2Trial Scottsdale/Phoenix, Ariz. The purpose of this Long-Term Observational Extension of Participants in the CREST-2 Randomized Clinical Trial study is to assess post-procedural efficiency of carotid endarterectomy and carotid stenting. A Study of Immune-Mediated Activation of Astrocytes in Healthy Volunteers Rochester, Minn. The purpose of this study is to characterize the astrocyte response to various inflammatory drivers in the presence of innate immune cells collected from healthy subjects. We will identify innate immune cell populations that contribute to astrocyte reactivity and elucidate the mechanisms responsible for altering the transcriptional and translational profile of astrocytes. A Study to Evaluate Sleep for Stroke Management and Recovery Rochester, Minn. The purpose of this study is to determine whether treatment of obstructive sleep apnea (OSA) with positive airway pressure starting shortly after acute ischemic stroke or high risk TIA (1) reduces recurrent stroke, acute coronary syndrome, and all-cause mortality 6 months after the event, and (2) improves stroke outcomes at 3 months in patients who experienced an ischemic stroke. Pagination 临床研究 PrevPrevious Page Go to page 66 Go to page 77 Go to page 88 Go to page 99 Go to page 1010 NextNext Page 医疗专业人员 Neurology & Neurosurgery clinical-trials