Proper Use

Drug information provided by: Merative, Micromedex®

Medicines used to treat cancer are very strong and can have many side effects. Before using this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

A nurse or other trained health professional will give you this medicine. It is given through an IV catheter that is placed into one of your veins. It must be given slowly, so the IV will have to remain in place for at least 1 hour. Your treatment schedule is divided into cycles that are usually 28 days long.

You will receive this medicine on a "step-up dosing schedule." This means you will receive a smaller dose on Day 1 of your first treatment cycle. Then, you will receive the full treatment dose on Day 8 and Day 15 of Cycle 1. You will receive your full dose every 2 weeks after Day 15 of Cycle 1.

Your doctor will ask you to stay in a medical facility during treatment with this medicine:

  • For 22 to 24 hours on Day 1 and Day 8 of Cycle 1 doses.
  • For 6 to 8 hours on Day 15 of Cycle 1 and Cycle 2 doses.
  • For 3 to 4 hours on Cycle 3 and Cycle 4 doses.
  • For 2 hours on Cycle 5 and later doses.

This medicine comes with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

Your may also receive extra fluids and other medicines (eg, steroid medicine) within 1 hour before or immediately after starting treatment with this medicine.