Precautions

Drug information provided by: Merative, Micromedex®

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Blood tests may be needed to check for unwanted effects.

You should not use this medicine together with alfuzosin (Uroxatral®), apalutamide (Erleada®), colchicine (Colcrys®), eletriptan (Relpax®), eplerenone (Inspra®), finerenone (Kerendia®), flibanserin (Addyi®), ivabradine (Corlanor®), lomitapide (Juxtapid®), lovastatin (Mevacor®), lumacaftor/ivacaftor (Orkambi®), lurasidone (Latuda®), midazolam (Versed®), naloxegol (Movantik®), pethidine (Demerol®), pimozide (Orap®), ranolazine (Ranexa®), rifampin (Rifadin®), sildenafil (Viagra®), silodosin (Rapaflo®), simvastatin (Zocor®), St John's wort, tolvaptan (Samsca®), triazolam (Halcion®), ubrogepant (Ubrelvy®), voclosporin (Lupkynis®), ergot medicine (eg, dihydroergotamine, ergotamine, methylergonovine, Ergomar®, Methergine®, Migranal®), medicine for heart rhythm problems (eg, amiodarone, dronedarone, flecainide, propafenone, quinidine, Cardioquin®, Multaq®, Pacerone®, Rythmol®, Tambocor®), or seizure medicine (eg, carbamazepine, phenobarbital, phenytoin, primidone, Dilantin®, Mysoline®, Solfoton®, Tegretol®).

Tell your doctor if you are pregnant or planning to become pregnant. Birth control pills may not work as well to prevent pregnancy when used with this medicine. Use another form of birth control (eg, condoms or spermicide) along with your pills.

This medicine may cause serious allergic reactions, including anaphylaxis, angioedema, which can be life-threatening and require immediate medical attention. Check with your doctor right away if you have chest tightness, cough, difficulty swallowing, dizziness, fast heartbeat, hives, itching, or skin rash, large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, puffiness or swelling of the eyelids, or around the eyes, face, lips, or tongue, or unusual tiredness or weakness.

This medicine may cause serious skin reactions, including toxic epidermal necrolysis and Stevens-Johnson syndrome, which can be life-threatening and require immediate medical attention. Check with your doctor right away if you have blistering, peeling, or loosening of the skin, chills, cough, diarrhea, itching, joint or muscle pain, red irritated eyes, red skin lesions, often with a purple center, sore throat, sores, ulcers, or white spots in the mouth or on the lips, or unusual tiredness or weakness.

Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, vomiting, or yellow eyes or skin. These could be symptoms of a serious liver problem.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Portions of this document last updated: July 01, 2024

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