贮袋炎

概述

贮袋炎是指发生在结肠袋内膜中的炎症，其中结肠袋是手术期间创建用于治疗溃疡性结肠炎或某些其他疾病的袋。许多溃疡性结肠炎患者均需接受回肠肛管吻合术 （J 型贮袋术），以切除病变结肠，并重新连接肠道。

在 J 型贮袋术中，外科医生会用小肠末端（回肠）创建一个类似字母 J 的结肠袋。该结肠袋与肛门上方的区域相连，以用于在排出排泄物之前保存排泄物。

贮袋炎是 J 型贮袋术的并发症之一。这种并发症发生在约四分之一到一半接受该手术的患者中。

症状

贮袋炎的体征和症状包括腹泻、腹痛、关节疼痛、绞痛和发热。其他体征和症状包括大便次数增多，夜间漏便，无法控制大便以及强烈的便意。

病因

The cause of pouchitis is unknown. The condition appears to be due to an interaction between bacteria in the pouch and an underlying issue with the immune system.

风险因素

Some factors that can increase the risk of developing pouchitis include:

• Having inflammatory bowel disease, also called IBD. Pouchitis happens more often in people who have underlying IBD, such as ulcerative colitis.
• Using nonsteroidal anti-inflammatory drugs, also called NSAIDs. Taking NSAIDS, such as ibuprofen (Advil, Motrin IB) and naproxen sodium (Aleve), can contribute to the development of pouchitis.
• Having radiation therapy. Radiation therapy in the pelvic area increases the risk of getting pouchitis.

临床试验

探索 Mayo Clinic 的研究 测试新的治疗、干预与检查方法，旨在预防、检测、治疗或控制这种疾病。

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