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Steven S. Rosenfeld, M.D., Ph.D.

  1. Neurologist
预约门诊

出版物

  1. Cheng YL, Banu MA, Zhao W, Rosenfeld SS, Canoll P, Sims PA. Multiplexed single-cell lineage tracing of mitotic kinesin inhibitor resistance in glioblastoma. Cell Rep. 2024 May 28; 43 (5):114139 Epub 2024 Apr 21
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  2. Schaeffer EM, Srinivas S, Adra N, An Y, Bitting R, Chapin B, Cheng HH, D'Amico AV, Desai N, Dorff T, Eastham JA, Farrington TA, Gao X, Gupta S, Guzzo T, Ippolito JE, Karnes RJ, Kuettel MR, Lang JM, Lotan T, McKay RR, Morgan T, Pow-Sang JM, Reiter R, Roach M, Robin T, Rosenfeld S, Shabsigh A, Spratt D, Szmulewitz R, Teply BA, Tward J, Valicenti R, Wong JK, Snedeker J, Freedman-Cass DA. Prostate Cancer, Version 3.2024. J Natl Compr Canc Netw. 2024 Apr; 22 (3):140-150
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  3. Quinones-Hinojosa A, Basil A, Moniz-Garcia D, Suarez-Meade P, Ramos A, Jentoft M, Middlebrooks E, Grewal S, Abode-Iyamah K, Bydon M, Sarkaria J, Dickson D, Swanson K, Rosenfeld S, Schiapparelli P, Guerrero-Cazares H, Chaichana K, Meyer F. From the Operating Room to the Laboratory: Role of the Neuroscience Tissue Biorepository in the Clinical, Translational, and Basic Science Research Pipeline. Mayo Clin Proc. 2024 Feb; 99 (2):229-240
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  4. Moniz-Garcia D, Bojaxhi E, Borah BJ, Dholakia R, Kim H, Sousa-Pinto B, Almeida JP, Mendhi M, Freeman WD, Sherman W, Christel L, Rosenfeld S, Grewal SS, Middlebrooks EH, Sabsevitz D, Gruenbaum BF, Chaichana KL, Quinones-Hinojosa A. Awake Craniotomy Program Implementation. JAMA Netw Open. 2024 Jan 2; 7 (1):e2352917 Epub 2024 Jan 02
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  5. Southern BD, Li H, Mao H, Crish JF, Grove LM, Scheraga RG, Mansoor S, Reinhardt A, Abraham S, Deshpande G, Loui A, Ivanov AI, Rosenfeld SS, Bresnick AR, Olman MA. A novel mechanoeffector role of fibroblast S100A4 in myofibroblast transdifferentiation and fibrosis. J Biol Chem. 2024 Jan; 300 (1):105530 Epub 2023 Dec 10
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  6. Chaichana Kaisorn, Grewal Sanjeet, Middlebrooks Erik, Bojaxhi Elird, Gruenbaum Benjamin, Christel Lynda, Borah Bijan, Dholakia Ruchita, Kim Han, Cavalcante de Almeida, Freeman William, Sherman Wendy, Rosenfeld Steven, Sabsevitz David, Quinones-Hinojosa Alfredo. Awake Craniotomy Program Implementation: a Cost-Utility Analysis JAMA. 2023.
  7. Nithianantham S, Iwanski MK, Gaska I, Pandey H, Bodrug T, Inagaki S, Major J, Brouhard GJ, Gheber L, Rosenfeld SS, Forth S, Hendricks AG, Al-Bassam J. The kinesin-5 tail and bipolar minifilament domains are the origin of its microtubule crosslinking and sliding activity. Mol Biol Cell. 2023 Oct 1; 34 (11):ar111 Epub 2023 Aug 23
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  8. Ranaivoson FM, Crozet V, Benoit MPMH, Abdalla Mohammed Khalid A, Kikuti C, Sirkia H, El Marjou A, Miserey-Lenkei S, Asenjo AB, Sosa H, Schmidt CF, Rosenfeld SS, Houdusse A. Nucleotide-free structures of KIF20A illuminate atypical mechanochemistry in this kinesin-6. Open Biol. 2023 Sep; 13 (9):230122 Epub 2023 Sept 20
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  9. Feyissa AM, Rosenfeld SS, Quinones-Hinojosa A. Altered glutamatergic and inflammatory pathways promote glioblastoma growth, invasion, and seizures: An overview. J Neurol Sci. 2022 Dec 15; 443:120488 Epub 2022 Nov 05
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  10. Schaeffer EM, Srinivas S, Adra N, An Y, Barocas D, Bitting R, Bryce A, Chapin B, Cheng HH, D'Amico AV, Desai N, Dorff T, Eastham JA, Farrington TA, Gao X, Gupta S, Guzzo T, Ippolito JE, Kuettel MR, Lang JM, Lotan T, McKay RR, Morgan T, Netto G, Pow-Sang JM, Reiter R, Roach M, Robin T, Rosenfeld S, Shabsigh A, Spratt D, Teply BA, Tward J, Valicenti R, Wong JK, Berardi RA, Shead DA, Freedman-Cass DA. Prostate cancer, version 1.2023 featured updates to the nccn guidelines. Journal Of The National Comprehensive Cancer Network. 2022 Dec; 20 (12):1288-98
  11. Kenchappa RS, Dovas A, Argenziano MG, Meyer CT, Stopfer LE, Banu MA, Pereira B, Griffith J, Mohammad A, Talele S, Haddock A, Zarco N, Elmquist W, White F, Quaranta V, Sims P, Canoll P, Rosenfeld SS. Activation of STAT3 through combined SRC and EGFR signaling drives resistance to a mitotic kinesin inhibitor in glioblastoma. Cell Rep. 2022 Jun 21; 39 (12):110991
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  12. Kenchappa RS, Liu Y, Argenziano MG, Banu MA, Mladek AC, West R, Luu A, Quinones-Hinojosa A, Hambardzumyan D, Justilien V, Leitges M, Sarkaria JN, Sims PA, Canoll P, Murray NR, Fields AP, Rosenfeld SS. Protein kinase C(iota) and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities. Cell Rep. 2021 Nov 23; 37 (8):110054
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  13. Pandey H, Singh SK, Sadan M, Popov M, Singh M, Davidov G, Inagaki S, Al-Bassam J, Zarivach R, Rosenfeld SS, Gheber L. Flexible microtubule anchoring modulates the bi-directional motility of the kinesin-5 Cin8. Cell Mol Life Sci. 2021 Aug; 78 (16):6051-6068 Epub 2021 July 17
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  14. Feyissa AM, Carrano A, Wang X, Allen M, Ertekin-Taner N, Dickson DW, Jentoft ME, Rosenfeld SS, Tatum WO, Ritaccio AL, Guerrero-Cazares H, Quinones-Hinojosa A. Analysis of intraoperative human brain tissue transcriptome reveals putative risk genes and altered molecular pathways in glioma-related seizures. Epilepsy Res. 2021 Jul; 173:106618 Epub 2021 Mar 18
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  15. Kenchappa RS, Mistriotis P, Wisniewski E, Bhattacharya S, Kulkarni T, West R, Luu A, Conlon M, Heimsath E, Crish JF, Picariello HS, Dovas A, Zarco N, Lara-Velazquez M, Quinones-Hinojosa A, Hammer JA, Mukhopadhyay D, Cheney RE, Konstantopoulos K, Canoll P, Rosenfeld SS. Myosin 10 Regulates Invasion, Mitosis, and Metabolic Signaling in Glioblastoma. iScience. 2020 Dec 18; 23 (12):101802 Epub 2020 Nov 13
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  16. Atherton J, Hummel JJ, Olieric N, Locke J, Pena A, Rosenfeld SS, Steinmetz MO, Hoogenraad CC, Moores CA. The mechanism of kinesin inhibition by kinesin-binding protein. Elife. 2020 Nov 30; 9
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  17. Gampa G, Kenchappa RS, Mohammad AS, Parrish KE, Kim M, Crish JF, Luu A, West R, Hinojosa AQ, Sarkaria JN, Rosenfeld SS, Elmquist WF. Enhancing Brain Retention of a KIF11 Inhibitor Significantly Improves its Efficacy in a Mouse Model of Glioblastoma. Sci Rep. 2020 Apr 16; 10 (1):6524
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  18. Bodrug T, Wilson-Kubalek EM, Nithianantham S, Thompson AF, Alfieri A, Gaska I, Major J, Debs G, Inagaki S, Gutierrez P, Gheber L, McKenney RJ, Sindelar CV, Milligan R, Stumpff J, Rosenfeld SS, Forth ST, Al-Bassam J. The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding. Elife. 2020 Jan 20; 9
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  19. Deng Q, Hu H, Yu X, Liu S, Wang L, Chen W, Zhang C, Zeng Z, Cao Y, Xu-Monette ZY, Li L, Zhang M, Rosenfeld S, Bao S, Hsi E, Young KH, Lu Z, Li Y. Tissue-specific microRNA expression alters cancer susceptibility conferred by a TP53 noncoding variant. Nat Commun. 2019 Nov 7; 10 (1):5061 Epub 2019 Nov 07
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  20. Aulakh S, DeDeo MR, Free J, Rosenfeld SS, Quinones-Hinojosa A, Paulus A, Manna A, Manochakian R, Chanan-Khan AA, Ailawadhi S. Survival trends in glioblastoma and association with treating facility volume. J Clin Neurosci. 2019 Oct; 68:271-274 Epub 2019 May 24
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  21. Picariello HS, Kenchappa RS, Rai V, Crish JF, Dovas A, Pogoda K, McMahon M, Bell ES, Chandrasekharan U, Luu A, West R, Lammerding J, Canoll P, Odde DJ, Janmey PA, Egelhoff T, Rosenfeld SS. Myosin IIA suppresses glioblastoma development in a mechanically sensitive manner. Proc Natl Acad Sci U S A. 2019 Jul 30; 116 (31):15550-15559 Epub 2019 June 24
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  22. Cantrell JN, Waddle MR, Rotman M, Peterson JL, Ruiz-Garcia H, Heckman MG, Quinones-Hinojosa A, Rosenfeld SS, Brown PD, Trifiletti DM. Progress Toward Long-Term Survivors of Glioblastoma. Mayo Clin Proc. 2019 Jul; 94 (7):1278-1286 Epub 2019 June 20
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  23. Feyissa AM, Worrell GA, Tatum WO, Chaichana KL, Jentoft ME, Guerrero Cazares H, Ertekin-Taner N, Rosenfeld SS, ReFaey K, Quinones-Hinojosa A. Potential influence of IDH1 mutation and MGMT gene promoter methylation on glioma-related preoperative seizures and postoperative seizure control. Seizure. 2019 Jul; 69:283-289 Epub 2019 May 20
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  24. Mahato D, De Biase G, Ruiz-Garcia HJ, Grover S, Rosenfeld S, Quinones-Hinojosa A, Trifiletti DM. Impact of facility type and volume on post-surgical outcomes following diagnosis of WHO grade II glioma. J Clin Neurosci. 2018 Dec; 58:34-41 Epub 2018 Oct 23
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  25. Prahl LS, Bangasser PF, Stopfer LE, Hemmat M, White FM, Rosenfeld SS, Odde DJ. Microtubule-Based Control of Motor-Clutch System Mechanics in Glioma Cell Migration. Cell Rep. 2018 Nov 27; 25 (9):2591-2604.e8
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  26. Dutta SW, Peterson JL, Vallow LA, Mahajan A, Rosenfeld SS, Quinones-Hinojosa A, Trifiletti DM. National care among patients with WHO grade I intracranial meningioma. J Clin Neurosci. 2018 Sep; 55:17-24 Epub 2018 June 15
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  27. Feyissa AM, Worrell GA, Tatum WO, Mahato D, Brinkmann BH, Rosenfeld SS, ReFaey K, Bechtle PS, Quinones-Hinojosa A. High-frequency oscillations in awake patients undergoing brain tumor-related epilepsy surgery. Neurology. 2018 Mar 27; 90 (13):e1119-e1125 Epub 2018 Feb 28
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  28. Muretta JM, Reddy BJN, Scarabelli G, Thompson AF, Jariwala S, Major J, Venere M, Rich JN, Willard B, Thomas DD, Stumpff J, Grant BJ, Gross SP, Rosenfeld SS. A posttranslational modification of the mitotic kinesin Eg5 that enhances its mechanochemical coupling and alters its mitotic function. Proc Natl Acad Sci U S A. 2018 Feb 20; 115 (8):E1779-E1788 Epub 2018 Feb 05
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  29. Atherton J, Yu IM, Cook A, Muretta JM, Joseph A, Major J, Sourigues Y, Clause J, Topf M, Rosenfeld SS, Houdusse A, Moores CA. The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry. Elife. 2017 Aug 11; 6
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  30. Bangasser BL, Shamsan GA, Chan CE, Opoku KN, Tuzel E, Schlichtmann BW, Kasim JA, Fuller BJ, McCullough BR, Rosenfeld SS, Odde DJ. Shifting the optimal stiffness for cell migration. Nat Commun. 2017 May 22; 8:15313.
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  31. Klank RL, Decker Grunke SA, Bangasser BL, Forster CL, Price MA, Odde TJ, SantaCruz KS, Rosenfeld SS, Canoll P, Turley EA, McCarthy JB, Ohlfest JR, Odde DJ. Biphasic Dependence of Glioma Survival and Cell Migration on CD44 Expression Level. Cell Rep. 2017 Apr 18; 19 (3):668
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  32. Southern BD, Grove LM, Rahaman SO, Abraham S, Scheraga RG, Niese KA, Sun H, Herzog EL, Liu F, Tschumperlin DJ, Egelhoff TT, Rosenfeld SS, Olman MA. Matrix-driven Myosin II Mediates the Pro-fibrotic Fibroblast Phenotype. J Biol Chem. 2016 Mar 18; 291 (12):6083-95 Epub 2016 Jan 13
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  33. Nayak L, DeAngelis LM, Robins HI, Govindan R, Gadgeel S, Kelly K, Rigas JR, Peereboom DM, Rosenfeld SS, Muzikansky A, Zheng M, Urban P, Abrey LE, Omuro A, Wen PY. Multicenter phase 2 study of patupilone for recurrent or progressive brain metastases from non-small cell lung cancer. Cancer. 2015 Dec 01; 121: (23)4165-72.
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  34. Muretta JM, Jun Y, Gross SP, Major J, Thomas DD, Rosenfeld SS. The structural kinetics of switch-1 and the neck linker explain the functions of kinesin-1 and Eg5. Proc Natl Acad Sci U S A. 2015 Dec 01; 112: (48)E6606-13.
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  35. Shojania Feizabadi M, Janakaloti Narayanareddy BR, Vadpey O, Jun Y, Chapman D, Rosenfeld S, Gross SP. Microtubule C-Terminal Tails Can Change Characteristics of Motor Force Production. Traffic. 2015 Oct; 16: (10)1075-87.
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  36. Venere M, Horbinski C, Crish JF, Jin X, Vasanji A, Major J, Burrows AC, Chang C, Prokop J, Wu Q, Sims PA, Canoll P, Summers MK, Rosenfeld SS, Rich JN. The mitotic kinesin KIF11 is a driver of invasion, proliferation, and self-renewal in glioblastoma. Sci Transl Med. 2015 Sep 09; 7: (304)304ra143.
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  37. Gittleman HR, Ostrom QT, Rouse CD, Dowling JA, de Blank PM, Kruchko CA, Elder JB, Rosenfeld SS, Selman WR, Sloan AE, Barnholtz-Sloan JS. Trends in central nervous system tumor incidence relative to other common cancers in adults, adolescents, and children in the United States, 2000 to 2010. Cancer. 2015 Jan 01; 121: (1)102-12.
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  38. Atherton J, Farabella I, Yu IM, Rosenfeld SS, Houdusse A, Topf M, Moores CA. Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins. Elife. 2014 Sep 10; 3:e03680.
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  39. Chamberlain MC, Grimm S, Phuphanich S, Recht L, Zhu JZ, Kim L, Rosenfeld S, Fadul CE, Brain Tumor Investigational Consortium. A phase 2 trial of verubulin for recurrent glioblastoma: a prospective study by the Brain Tumor Investigational Consortium (BTIC). J Neurooncol. 2014 Jun; 118: (2)335-43.
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  40. Sonabend AM, Bansal M, Guarnieri P, Lei L, Amendolara B, Soderquist C, Leung R, Yun J, Kennedy B, Sisti J, Bruce S, Bruce R, Shakya R, Ludwig T, Rosenfeld S, Sims PA, Bruce JN, Califano A, Canoll P. The transcriptional regulatory network of proneural glioma determines the genetic alterations selected during tumor progression. Cancer Res. 2014 Mar 01; 74: (5)1440-1451.
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  41. Goulet A, Major J, Jun Y, Gross SP, Rosenfeld SS, Moores CA. Comprehensive structural model of the mechanochemical cycle of a mitotic motor highlights molecular adaptations in the kinesin family. Proc Natl Acad Sci U S A. 2014 Feb 04; 111: (5)1837-42.
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  42. Guan X, Vengoechea J, Zheng S, Sloan AE, Chen Y, Brat DJ, O'Neill BP, de Groot J, Yust-Katz S, Yung WK, Cohen ML, Aldape KD, Rosenfeld S, Verhaak RG, Barnholtz-Sloan JS. Molecular subtypes of glioblastoma are relevant to lower grade glioma. PLoS One. 2014; 9 (3):e91216 Epub 2014 Mar 10
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  43. Hess CW, Rosenfeld SS, Resor SR Jr. Oculomotor nerve palsy as the presenting symptom of gummatous neurosyphilis and human immunodeficiency virus infection: clinical response to treatment. JAMA Neurol. 2013 Dec; 70: (12)1582-3.
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  44. Muretta JM, Behnke-Parks WM, Major J, Petersen KJ, Goulet A, Moores CA, Thomas DD, Rosenfeld SS. Loop L5 assumes three distinct orientations during the ATPase cycle of the mitotic kinesin Eg5: a transient and time-resolved fluorescence study. J Biol Chem. 2013 Nov 29; 288: (48)34839-49.
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  45. Bangasser BL, Rosenfeld SS, Odde DJ. Determinants of maximal force transmission in a motor-clutch model of cell traction in a compliant microenvironment. Biophys J. 2013 Aug 06; 105: (3)581-92.
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  46. Kaan HY, Major J, Tkocz K, Kozielski F, Rosenfeld SS. "Snapshots" of ispinesib-induced conformational changes in the mitotic kinesin Eg5. J Biol Chem. 2013 Jun 21; 288: (25)18588-98.
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  47. Drappatz J, Brenner A, Wong ET, Eichler A, Schiff D, Groves MD, Mikkelsen T, Rosenfeld S, Sarantopoulos J, Meyers CA, Fielding RM, Elian K, Wang X, Lawrence B, Shing M, Kelsey S, Castaigne JP, Wen PY. Phase I study of GRN1005 in recurrent malignant glioma. Clin Cancer Res. 2013 Mar 15; 19: (6)1567-76.
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  48. Reardon DA, Groves MD, Wen PY, Nabors L, Mikkelsen T, Rosenfeld S, Raizer J, Barriuso J, McLendon RE, Suttle AB, Ma B, Curtis CM, Dar MM, de Bono J. A phase I/II trial of pazopanib in combination with lapatinib in adult patients with relapsed malignant glioma. Clin Cancer Res. 2013 Feb 15; 19: (4)900-8.
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  49. Goulet A, Behnke-Parks WM, Sindelar CV, Major J, Rosenfeld SS, Moores CA. The structural basis of force generation by the mitotic motor kinesin-5. J Biol Chem. 2012 Dec 28; 287: (53)44654-66.
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  50. D'Amico R, Lei L, Kennedy BC, Sisti J, Ebiana V, Crisman C, Christensen JG, Gil O, Rosenfeld SS, Canoll P, Bruce JN. The addition of Sunitinib to radiation delays tumor growth in a murine model of glioblastoma. Neurol Res. 2012 Apr; 34: (3)252-61.
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  51. Ivkovic S, Beadle C, Noticewala S, Massey SC, Swanson KR, Toro LN, Bresnick AR, Canoll P, Rosenfeld SS. Direct inhibition of myosin II effectively blocks glioma invasion in the presence of multiple motogens. Mol Biol Cell. 2012 Feb; 23: (4)533-42.
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  52. Bruce JN, Fine RL, Canoll P, Yun J, Kennedy BC, Rosenfeld SS, Sands SA, Surapaneni K, Lai R, Yanes CL, Bagiella E, DeLaPaz RL. Regression of recurrent malignant gliomas with convection-enhanced delivery of topotecan. Neurosurgery. 2011 Dec; 69: (6)1272-9; discussion 1279-80.
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  53. Clancy BE, Behnke-Parks WM, Andreasson JO, Rosenfeld SS, Block SM. A universal pathway for kinesin stepping. Nat Struct Mol Biol. 2011 Aug 14; 18: (9)1020-7.
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  54. Behnke-Parks WM, Vendome J, Honig B, Maliga Z, Moores C, Rosenfeld SS. Loop L5 acts as a conformational latch in the mitotic kinesin Eg5. J Biol Chem. 2011 Feb 18; 286: (7)5242-53.
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  55. Lei L, Sonabend AM, Guarnieri P, Soderquist C, Ludwig T, Rosenfeld S, Bruce JN, Canoll P. Glioblastoma models reveal the connection between adult glial progenitors and the proneural phenotype. PLoS One. 2011; 6: (5)e20041.
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  56. Phuphanich S, Supko JG, Carson KA, Grossman SA, Burt Nabors L, Mikkelsen T, Lesser G, Rosenfeld S, Desideri S, Olson JJ. Phase 1 clinical trial of bortezomib in adults with recurrent malignant glioma. J Neurooncol. 2010 Oct; 100: (1)95-103.
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  57. Rosenfeld SS, van Duffelen M, Behnke-Parks WM, Beadle C, Corrreia J, Xing J. The ATPase cycle of the mitotic motor CENP-E. J Biol Chem. 2009 Nov 20; 284: (47)32858-68.
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  58. Toprak E, Yildiz A, Hoffman MT, Rosenfeld SS, Selvin PR. Why kinesin is so processive. Proc Natl Acad Sci U S A. 2009 Aug 04; 106: (31)12717-22.
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  59. Beadle C, Assanah MC, Monzo P, Vallee R, Rosenfeld SS, Canoll P. The role of myosin II in glioma invasion of the brain. Mol Biol Cell. 2008 Aug; 19: (8)3357-68.
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  60. Yardimci H, van Duffelen M, Mao Y, Rosenfeld SS, Selvin PR. The mitotic kinesin CENP-E is a processive transport motor. Proc Natl Acad Sci U S A. 2008 Apr 22; 105: (16)6016-21.
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  61. Shah GD, Silver JS, Rosenfeld SS, Gavrilovic IT, Abrey LE, Lassman AB. Myelosuppression in patients benefiting from imatinib with hydroxyurea for recurrent malignant gliomas. J Neurooncol. 2007 Nov; 85: (2)217-22.
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  62. Sweeney HL, Park H, Zong AB, Yang Z, Selvin PR, Rosenfeld SS. How myosin VI coordinates its heads during processive movement. EMBO J. 2007 Jun 06; 26: (11)2682-92.
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  63. Nabors LB, Mikkelsen T, Rosenfeld SS, Hochberg F, Akella NS, Fisher JD, Cloud GA, Zhang Y, Carson K, Wittemer SM, Colevas AD, Grossman SA. Phase I and correlative biology study of cilengitide in patients with recurrent malignant glioma. J Clin Oncol. 2007 May 01; 25: (13)1651-7.
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  64. Mamelak AN, Rosenfeld S, Bucholz R, Raubitschek A, Nabors LB, Fiveash JB, Shen S, Khazaeli MB, Colcher D, Liu A, Osman M, Guthrie B, Schade-Bijur S, Hablitz DM, Alvarez VL, Gonda MA. Phase I single-dose study of intracavitary-administered iodine-131-TM-601 in adults with recurrent high-grade glioma. J Clin Oncol. 2006 Aug 01; 24: (22)3644-50.
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  65. Abrey LE, Childs BH, Paleologos N, Kaminer L, Rosenfeld S, Salzman D, Finlay JL, Gardner S, Peterson K, Hu W, Swinnen L, Bayer R, Forsyth P, Stewart D, Smith AM, Macdonald DR, Weaver S, Ramsay DA, Nimer SD, DeAngelis LM, Cairncross JG. High-dose chemotherapy with stem cell rescue as initial therapy for anaplastic oligodendroglioma: long-term follow-up. Neuro Oncol. 2006 Apr; 8: (2)183-8.
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  66. Maliga Z, Xing J, Cheung H, Juszczak LJ, Friedman JM, Rosenfeld SS. A pathway of structural changes produced by monastrol binding to Eg5. J Biol Chem. 2006 Mar 24; 281: (12)7977-82.
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  67. Rosenfeld SS, Xing J, Jefferson GM, King PH. Docking and rolling, a model of how the mitotic motor Eg5 works. J Biol Chem. 2005 Oct 21; 280: (42)35684-95.
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  68. Hook P, Mikami A, Shafer B, Chait BT, Rosenfeld SS, Vallee RB. Long range allosteric control of cytoplasmic dynein ATPase activity by the stalk and C-terminal domains. J Biol Chem. 2005 Sep 23; 280: (38)33045-54.
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  69. Brem SS, Bierman PJ, Black P, Blumenthal DT, Brem H, Chamberlain MC, Chiocca EA, DeAngelis LM, Fenstermaker RA, Fine HA, Friedman A, Glass J, Grossman SA, Heimberger AB, Junck L, Levin V, Loeffler JJ, Maor MH, Narayana A, Newton HB, Olivi A, Portnow J, Prados M, Raizer JJ, Rosenfeld SS, Shrieve DC, Sills AK Jr, Spence AM, Vrionis FD, National Comprehensive Cancer Network. Central nervous system cancers: Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2005 Sep; 3: (5)644-90.
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  70. Rosenfeld SS, Houdusse A, Sweeney HL. Magnesium regulates ADP dissociation from myosin V. J Biol Chem. 2005 Feb 18; 280: (7)6072-9.
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  71. Chiocca EA, Abbed KM, Tatter S, Louis DN, Hochberg FH, Barker F, Kracher J, Grossman SA, Fisher JD, Carson K, Rosenblum M, Mikkelsen T, Olson J, Markert J, Rosenfeld S, Nabors LB, Brem S, Phuphanich S, Freeman S, Kaplan R, Zwiebel J. A phase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-Attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant gliomas, in the adjuvant setting. Mol Ther. 2004 Nov; 10: (5)958-66.
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  72. Rosenfeld SS, Sweeney HL. A model of myosin V processivity. J Biol Chem. 2004 Sep 17; 279: (38)40100-11.
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  73. Bahloul A, Chevreux G, Wells AL, Martin D, Nolt J, Yang Z, Chen LQ, Potier N, Van Dorsselaer A, Rosenfeld S, Houdusse A, Sweeney HL. The unique insert in myosin VI is a structural calcium-calmodulin binding site. Proc Natl Acad Sci U S A. 2004 Apr 06; 101: (14)4787-92.
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  74. Abrey LE, Childs BH, Paleologos N, Kaminer L, Rosenfeld S, Salzman D, Finlay JL, Gardner S, Peterson K, Hu W, Swinnen L, Bayer R, Forsyth P, Stewart D, Smith AM, Macdonald DR, Weaver S, Ramsey DA, Nimer SD, DeAngelis LM, Cairncross JG. High-dose chemotherapy with stem cell rescue as initial therapy for anaplastic oligodendroglioma. J Neurooncol. 2003 Nov; 65: (2)127-34.
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  75. Rosenfeld SS, Xing J, Chen LQ, Sweeney HL. Myosin IIb is unconventionally conventional. J Biol Chem. 2003 Jul 25; 278: (30)27449-55.
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  76. Rosenfeld SS, Fordyce PM, Jefferson GM, King PH, Block SM. Stepping and stretching. How kinesin uses internal strain to walk processively. J Biol Chem. 2003 May 16; 278: (20)18550-6.
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  77. Aslan M, Ryan TM, Townes TM, Coward L, Kirk MC, Barnes S, Alexander CB, Rosenfeld SS, Freeman BA. Nitric oxide-dependent generation of reactive species in sickle cell disease. Actin tyrosine induces defective cytoskeletal polymerization. J Biol Chem. 2003 Feb 07; 278: (6)4194-204.
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  78. Ostap EM, Lin T, Rosenfeld SS, Tang N. Mechanism of regulation of Acanthamoeba myosin-IC by heavy-chain phosphorylation. Biochemistry. 2002 Oct 15; 41: (41)12450-6.
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  79. Rosenfeld SS, Xing J, Jefferson GM, Cheung HC, King PH. Measuring kinesin's first step. J Biol Chem. 2002 Sep 27; 277: (39)36731-9.
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  80. El Mezgueldi M, Tang N, Rosenfeld SS, Ostap EM. The kinetic mechanism of Myo1e (human myosin-IC). J Biol Chem. 2002 Jun 14; 277: (24)21514-21.
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  81. Cairncross G, Swinnen L, Bayer R, Rosenfeld S, Salzman D, Paleologos N, Kaminer L, Forsyth P, Stewart D, Peterson K, Hu W, Macdonald D, Ramsay D, Smith A, Oligodendroglioma Study Group. Myeloablative chemotherapy for recurrent aggressive oligodendroglioma. Neuro Oncol. 2000 Apr; 2: (2)114-9.
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  82. Halperin EC, Herndon J, Schold SC, Brown M, Vick N, Cairncross JG, Macdonald DR, Gaspar L, Fischer B, Dropcho E, Rosenfeld S, Morowitz R, Piepmeier J, Hait W, Byrne T, Salter M, Imperato J, Khandekar J, Paleologos N, Burger P, Bentel GC, Friedman A. A phase III randomized prospective trial of external beam radiotherapy, mitomycin C, carmustine, and 6-mercaptopurine for the treatment of adults with anaplastic glioma of the brain. CNS Cancer Consortium. Int J Radiat Oncol Biol Phys. 1996 Mar 01; 34: (4)793-802.
    View PubMed
  83. Hoffman JM, Waskin HA, Schifter T, Hanson MW, Gray L, Rosenfeld S, Coleman RE. FDG-PET in differentiating lymphoma from nonmalignant central nervous system lesions in patients with AIDS. J Nucl Med. 1993 Apr; 34: (4)567-75.
    View PubMed
  84. Friedman JM, Rousseau DL, Navon G, Rosenfeld S, Glynn P, Lyons KB. Ruthenium red as a resonance Raman probe of Ca2+ binding sites in biological materials. Arch Biochem Biophys. 1979 Mar; 193: (1)14-21.
    View PubMed
  85. Leavis PC, Rosenfeld S, Lu RC. Cleavage of a specific bond in troponin C by thrombin. Biochim Biophys Acta. 1978 Aug 21; 535: (2)281-6.
    View PubMed
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