搜索医生

Laura E. Raffals, M.D.

  1. Gastroenterologist
预约门诊

出版物

  1. Dunleavy KA, Santiago P, Forde G, Harmsen WS, McKenna NP, Coelho-Prabhu N, Shawki S, Raffals L. Total Proctocolectomy vs Subtotal/total Colectomy for Neoplasia in Patients With Inflammatory Bowel Disease and Primary Sclerosing Cholangitis. Inflamm Bowel Dis. 2024 Nov 4; 30 (11):1935-1945
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  2. Graff-Radford NR, Burke JR, Dickson DW, Ertekin-Taner N, Parisi JE, Petersen RC, Boeve BF, Allen M, Carrasquillo MM, Younkin SG, Yu L, Harrell LE, Miller CA, Yu CE, Morris JC, Johnson L, Kovacs GG, Katsumata Y, Wu X, Aung KZ, Fardo DW, Forrest SL, Nelson PT. Amyloid-beta predominant Alzheimer's disease neuropathologic change. Brain. 2024 Oct 17 [Epub ahead of print]
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  3. Syal G, Barnes E, Raffals L, Al Kazzi E, Haydek J, Agarwal M, Singh S. Medical Therapies for Prevention and Treatment of Inflammatory Pouch Disorders-A Systematic Review and Meta-Analysis. Am J Gastroenterol. 2024 Oct 16 [Epub ahead of print]
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  4. Murad MH, Shields R, Tabaja H, Adusumalli J, Dulai PS, Bonner LB, Sadler C, Raffals LE, Kochhar G, Lindholm P, Buckey JC Jr, Toups GN, Rosas L, Narula N, Jairath V, Honap S, Peyrin-Biroulet L, Sands BE, Hanauer SB, Scholtens DM, Siegel CA, HBOT-UC Consortium Investigators. Clinical Trial Design Considerations for Hospitalised Patients With Ulcerative Colitis Flares and Application to Study Hyperbaric Oxygen Therapy in the NIDDK HBOT-UC Consortium. Aliment Pharmacol Ther. 2024 Oct 15 [Epub ahead of print]
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  5. Yamanaka-Takaichi M, Nadalian S, Loftus EV, Ehman EC Jr, Todd A, Grimaldo AB, Yalon M, Matchett CL, Patel NB, Isaq NA, Raffals LE, Wetter DA, Murphree DH Jr, Cima RR, Dozois EJ, Goldfarb N, Tizhoosh HR, Alavi A. Differentiating clinical characteristics of perianal inflammatory bowel disease from perianal hidradenitis suppurativa. Int J Dermatol. 2024 Sep 22 Epub 2024 Sept 22
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  6. Kayal M, Spencer EA, Smyth M, Raffals L, Qazi T, Deepak P, Beniwal-Patel P, Chang S, Higgins P, Cross RK, Anderson C, Long M, Herfarth HH, Dubinsky MC, Barnes EL. Risankizumab Is Effective for The Management of Crohn's Disease of the Pouch. Inflamm Bowel Dis. 2024 Jul 22 Epub 2024 July 22
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  7. Santiago P, Quinn KP, Chen J, Friton JJ, Rypstra CR, Kashyap PC, Raffals LE. Altered Bile Acid and Pouch Microbiota Composition in Patients With Chronic Pouchitis. Inflamm Bowel Dis. 2024 Jul 3; 30 (7):1062-1070
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  8. Vasudevan A, Tharayil V, Raffals LH, Bruining DH, Becker M, Murad MH, Loftus EV Jr. Systematic Review and Meta-analysis: The Association Between Serum Ustekinumab Trough Concentrations and Treatment Response in Inflammatory Bowel Disease. Inflamm Bowel Dis. 2024 Apr 3; 30 (4):660-670
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  9. Kayal M, Deepak P, Beniwal-Patel P, Raffals L, Dubinsky M, Chang S, Higgins PDR, Jiang Y, Cross RK, Long MD, Herfarth HH, Barnes EL. Changes in Therapy Are Not Associated With Increased Remission in Patients With Crohn's Disease of the Pouch. Am J Gastroenterol. 2024 Mar 1; 119 (3):584-587 Epub 2023 Nov 17
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  10. Urquhart SA, Comstock BP, Jin MF, Day CN, Eaton JE, Harmsen WS, Raffals LE, Loftus EV Jr, Coelho-Prabhu N. The Incidence of Pouch Neoplasia Following Ileal Pouch-Anal Anastomosis in Patients With Inflammatory Bowel Disease. Inflamm Bowel Dis. 2024 Feb 01; 30(2):183-189.
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  11. Johnson AM, Harmsen WS, Aniwan S, Tremaine WJ, Raffals LE, Abu Dayyeh BK, Loftus EV. Prevalence and Impact of Obesity in a Population-Based Cohort of Patients With Crohn's Disease. J Clin Gastroenterol. 2024 Feb 1; 58 (2):176-182 Epub 2024 Feb 01
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  12. Barnes EL, Agrawal M, Syal G, Ananthakrishnan AN, Cohen BL, Haydek JP, Al Kazzi ES, Eisenstein S, Hashash JG, Sultan SS, Raffals LE, Singh S, AGA Clinical Guidelines Committee. Electronic address: clinicalpractice@gastro.org. AGA Clinical Practice Guideline on the Management of Pouchitis and Inflammatory Pouch Disorders. Gastroenterology. 2024 Jan; 166 (1):59-85
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  13. Braga-Neto MB, Nasser J, Wang XJ, Harmsen WS, Raffals LE, Camilleri M, Chedid V. Risk of Primary Gastrointestinal Lymphoma in Patients With Inflammatory Conditions Exposed to Tumor Necrosis Factor Alpha Inhibitors and Immunomodulators: A Case-Control Study. Crohns Colitis 360. 2024 Jan; 6 (1):otae010 Epub 2024 Feb 15
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  14. Santiago P, Coelho-Prabhu N, Lennon R, Rui S, Rajauria P, Friton J, Raffals LE, Deepali F, Daoud N, Farraye FA, Tuck J, Malik T, Leleiko NS, Shapiro J, Shah SA, Sands BE, Ungaro RC. Baseline Clinical Factors Are Associated With Risk of Complications in Crohn's Disease: Appraisal of the American Gastroenterological Association Clinical Care Pathway. Am J Gastroenterol. 2024 Jan 1; 119 (1):147-154 Epub 2023 Sept 15
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  15. Kang JY, Croghan IT, Matchett CL, Raffals LE, Schletty AA, Monson TR, Fischer KM, Pagel EM, Ghosh K, Bhagra A. Reflect, Inspire, Strengthen, and Empower 2.0 Program: Advancing Careers and Leadership for Women Physician Staff in an Academic Institution. Womens Health Rep (New Rochelle). 2024; 5(1):65-74. Epub 2024 Feb 01.
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  16. Santiago P, Coelho-Prabhu N, Lennon R, Rui S, Rajauria P, Friton J, Raffals LE, Deepali F, Daoud N, Farraye FA, Tuck J, Malik T, Leleiko NS, Shapiro J, Shah SA, Sands BE, Ungaro RC. Baseline clinical factors are associated with risk of complications in Crohn's disease: appraisal of the American Gastroenterological Association clinical care pathway. American Journal of Gastroenterology. 2024; 119 (1):147-54
  17. Guerrero Vinsard D, Lennon R, Avvaru HK, Patel M, Lahori S, Raffals LE, Coelho-Prabhu N. Measuring the concordance between endoscopic and histologic inflammation and its effect on IBD-associated dysplasia. Endosc Int Open. 2024 Jan; 12 (1):E145-E154 Epub 2024 Jan 30
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  18. Croghan IT, Kumar S, Dugani SB, Hurt RT, Raffals LE, Schletty AA, Schroeder DR, Gathje SR, Shah V. Writing Groups for Healthcare Professionals in Academic Medicine. J Prim Care Community Health. 2024 Jan-Dec; 15:21501319241266102
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  19. Lee YJ, Li D, Mujukian A, Debbas P, Hampton M, Mengesha E, Cheng S, Ebinger JE, Chiorean M, Lum D, Damas OM, Braun J, McGovern DPB, Melmed GY, Banty A, Feldman E, Ha C, Lee S, Rabizadeh S, Stein T, Solomon T, Syal G, Targan S, Vasiliauskas E, Ziring D, Bonthala N, Botwin GS, Hampton M, Mengesha E, Khanishian E, Pozdnyakova V, Gu P, White S, Zamudio C, Gonzalez D, Parry A, Hanna M, Chan J, Ebinger J, Joung S, Wu M, Hoang A, Wynter T, Sun N, Figueiredo JC, Merchant A, Merin N, Reckamp KL, Appel K, Kumar R, Boland B, Charabaty A, Chiorean M, Cohen E, Flynn A, Valentine J, Ehrlich AC, Fudman D, Horizon A, Karayev D, Kretzmann B, Hou J, Hwang C, Lazarev M, Lum D, Fausel R, Reddy S, McConnell R, Mattar MC, Metwally M, Ostrov A, Parekh N, Raffals L, Rubin DT, Sheibani S, Siegel CA, Wolf D, Younes Z. Postvaccination symptoms after a fourth dose of mRNA SARS-CoV-2 vaccination in patients with inflammatory bowel disease. Inflammatory Bowel Diseases. 2024; 30 (8):1430-4
  20. Dunleavy KA, Raffals LE, Camilleri M. Intestinal Barrier Dysfunction in Inflammatory Bowel Disease: Underpinning Pathogenesis and Therapeutics. Dig Dis Sci. 2023 Dec; 68 (12):4306-4320 Epub 2023 Sept 29
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  21. Santiago P, Barnes EL, Raffals LE. Classification and Management of Disorders of the J Pouch. Am J Gastroenterol. 2023 Nov 1; 118 (11):1931-1939 Epub 2023 May 30
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  22. Dunleavy KA, Cross RK, Raffals LE. Causes, Diagnostic Testing, and Treatment of Residual Symptoms in Patients With IBD With Quiescent Disease. Am J Gastroenterol. 2023 Nov 1; 118 (11):1909-1914 Epub 2023 Mar 28
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  23. Wang MH, Friton JJ, Raffals LE, Leighton JA, Pasha SF, Picco MF, Monroe K, Nix BD, Newberry RD, Faubion WA. Polygenic risk score predicts risk of primary sclerosing cholangitis in inflammatory bowel disease. BMJ Open Gastroenterol. 2023 Oct; 10 (1)
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  24. Wang MH, Friton JJ, Rebert N, Monroe K, Nix BD, Fiocchi C, Raffals LE, Leighton JA, Pasha SF, Picco MF, Newberry RD, Achkar JP, Faubion WA. Novel Genetic Risk Variants and Clinical Predictors Associated With Primary Sclerosing Cholangitis in Patients With Ulcerative Colitis. Clin Transl Gastroenterol. 2023 Sep 1; 14 (9):e00615 Epub 2023 Sept 01
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  25. Barnes EL, Beniwal-Patel P, Deepak P, Raffals L, Kayal M, Dubinsky M, Chang S, Higgins PDR, Barr JI, Anderson C, Cross RK, Long MD, Herfarth HH. Dietary Patterns Are Not Associated With Disease Activity Among Patients With Inflammatory Conditions of the Pouch in a Prospective Cohort. Crohns Colitis 360. 2023 Jul; 5 (3):otad039 Epub 2023 July 27
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  26. Deepak P, Jiang Y, Barnes EL, Long MD, Raffals L, Isaacs K, Stidham RW, Herfarth HH, Contributors. Development of the Endoscopic Pouch Score for Assessment of Inflammatory Conditions of the Pouch. Clin Gastroenterol Hepatol. 2023 Jun; 21 (6):1663-1666.e3 Epub 2022 May 12
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  27. Guerrero Vinsard D, Bruining DH, East JE, Ebner D, Kane SV, Kisiel JB, Leighton JA, Lennon RJ, Loftus EV Jr, Malik T, Picco M, Raffals L, Ramos GP, Santiago P, Coelho-Prabhu N. Interobserver agreement of the modified Paris classification and histology prediction of colorectal lesions in patients with inflammatory bowel disease. Gastrointest Endosc. 2023 Apr; 97 (4):790-798.e2 Epub 2022 Nov 17
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  28. Yamanaka-Takaichi M, Raffals LE, Ehman EC, Loftus EV Jr, Alavi A. Anemia and Systemic Inflammatory Markers in Patients with Perianal Disease: Hidradenitis Suppurativa and Inflammatory Bowel Disease. Dermatology 2023; 239 (5):843-848 Epub 2023 June 23
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  29. Tome J, Raffals LE, Pardi DS. Management of Acute and Chronic Pouchitis. Dis Colon Rectum. 2022 Dec 1; 65 (S1):S69-S76 Epub 2022 July 25
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  30. Syal G, Sparrow MP, Velayos F, Cheifetz AS, Devlin S, Irving PM, Kaplan GG, Raffals LE, Ullman T, Gecse KB, Fleshner PR, Lightner AL, Siegel CA, Melmed GY. Appropriateness of Medical and Surgical Treatments for Chronic Pouchitis Using RAND/UCLA Appropriateness Methodology. Dig Dis Sci. 2022 Oct; 67 (10):4687-4694 Epub 2022 Jan 10
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  31. Abd El Aziz MA, Larson DW, Grass F, D'Angelo AD, Kelley SR, Raffals LE, Mathis KL, Shawki S. Emergent and Urgent Surgery for Ulcerative Colitis in the United States in the Minimally Invasive and Biologic Era. Dis Colon Rectum. 2022 Aug 1; 65 (8):1025-1033 Epub 2022 July 05
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  32. Dulai PS, Rai V, Raffals LE, Lukin D, Hudesman D, Kochhar GS, Damas OM, Sauk JS, Levy AN, Sofia MA, Tuskey A, Deepak P, Yarur AJ, Afzali A, Ananthakrishnan AN, Cross RK, Hanauer SB, Siegel CA. Recommendations on the Appropriate Management of Steroids and Discharge Planning During and After Hospital Admission for Moderate-Severe Ulcerative Colitis: Results of a RAND Appropriateness Panel. Am J Gastroenterol. 2022 Aug 1; 117 (8):1288-1295 Epub 2022 Apr 13
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  33. Caine NA, Ebbert JO, Raffals LE, Philpot LM, Sundsted KK, Mikhail AE, Issa M, Schletty AA, Shah VH. A 2030 Vision for the Mayo Clinic Department of Medicine. Mayo Clin Proc. 2022 Jul; 97 (7):1232-1236
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  34. Barnes EL, Deepak P, Beniwal-Patel P, Raffals L, Kayal M, Dubinsky M, Chang S, Higgins PDR, Barr JI, Galanko J, Jiang Y, Cross RK, Long MD, Herfarth HH. Treatment Patterns and Standardized Outcome Assessments Among Patients With Inflammatory Conditions of the Pouch in a Prospective Multicenter Registry. Crohns Colitis 360. 2022 Jul; 4 (3):otac030 Epub 2022 Aug 02
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  35. Quinn KP, Busciglio IA, Burton DD, Inoue A, Lee YS, Heiken JP, Sheedy SP, Fletcher JG, Raffals LE. Defining normal pouch function in patients with ileal pouch-anal anastomosis: a pilot study. Aliment Pharmacol Ther. 2022 Jun; 55 (12):1560-1568 Epub 2022 Mar 11
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  36. Caine, NA, Ebbert JO, Raffals L, Philpot L, Sundsted K, Mikhail AE, Issa M, Schletty A, Shah VH. Perspective and Controversy: A 2030 Vision for the Mayo Clinic Department of Medicine Mayo Clinic Proceedings. 2022.
  37. Quinn KP, Urquhart SA, Janssens LP, Lennon RJ, Chedid VG, Raffals LE. Primary Sclerosing Cholangitis-Associated Pouchitis: A Distinct Clinical Phenotype. Clin Gastroenterol Hepatol. 2022 May; 20 (5):e964-e973 Epub 2021 Feb 04
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  38. Fredrick TW, Ramos GP, Braga Neto MB, Kane S, Faubion WA, Loftus EV Jr, Pardi DS, Pasha SF, Farraye FA, Zhang L, Raffals LE. Clinical Course and Impact of Immune Checkpoint Inhibitor Colitis Resembling Microscopic Colitis. Crohns Colitis 360. 2022 Apr; 4 (2):otac008 Epub 2022 Mar 15
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  39. Raffals LE, Saha S, Bewtra M, Norris C, Dobes A, Heller C, O'Charoen S, Fehlmann T, Sweeney S, Weaver A, Bishu S, Cross R, Dassopoulos T, Fischer M, Yarur A, Hudesman D, Parakkal D, Duerr R, Caldera F, Korzenik J, Pekow J, Wells K, Bohm M, Perera L, Kaur M, Ciorba M, Snapper S, Scoville EA, Dalal S, Wong U, Lewis JD. The Development and Initial Findings of A Study of a Prospective Adult Research Cohort with Inflammatory Bowel Disease (SPARC IBD). Inflamm Bowel Dis. 2022 Feb 1; 28 (2):192-199
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  40. Gonzalez CG, Mills RH, Kordahi MC, Carrillo-Terrazas M, Secaira-Morocho H, Widjaja CE, Tsai MS, Mittal Y, Yee BA, Vargas F, Weldon K, Gauglitz JM, Delaroque C, Sauceda C, Rossitto LA, Ackermann G, Humphrey G, Swafford AD, Siegel CA, Buckey JC Jr, Raffals LE, Sadler C, Lindholm P, Fisch KM, Valaseck M, Suriawinata A, Yeo GW, Ghosh P, Chang JT, Chu H, Dorrestein P, Zhu Q, Chassaing B, Knight R, Gonzalez DJ, Dulai PS. The Host-Microbiome Response to Hyperbaric Oxygen Therapy in Ulcerative Colitis Patients. Cell Mol Gastroenterol Hepatol. 2022; 14 (1):35-53 Epub 2022 Apr 01
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  41. Pozdnyakova V, Botwin GJ, Sobhani K, Prostko J, Braun J, Mcgovern DPB, Melmed GY, Appel K, Banty A, Feldman E, Ha C, Kumar R, Lee S, Rabizadeh S, Stein T, Syal G, Targan S, Vasiliauskas E, Ziring D, Debbas P, Hampton M, Mengesha E, Stewart JL, Frias EC, Cheng S, Ebinger J, Figueiredo JC, Boland B, Charabaty A, Chiorean M, Cohen E, Flynn A, Valentine J, Fudman D, Horizon A, Hou J, Hwang C, Lazarev M, Lum D, Fausel R, Reddy S, Mattar M, Metwally M, Ostrov A, Parekh N, Raffals L, Sheibani S, Siegel C, Wolf D, Younes Z. Decreased Antibody Responses to Ad26.COV2.S Relative to SARS-CoV-2 mRNA Vaccines in Patients With Inflammatory Bowel Disease. Gastroenterology. 2021 Dec; 161 (6):2041-2043.e1 Epub 2021 Aug 12
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  42. Wang MH, Friton JJ, Raffals LE, Leighton JA, Pasha SF, Picco MF, Monroe K, Nix BD, Newberry RD, Faubion WA. Novel Genetic Variant Predicts Surgical Recurrence Risk in Crohn's Disease Patients. Inflamm Bowel Dis. 2021 Nov 15; 27 (12):1968-1974
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  43. Cho JM, Loftus EV Jr, Bruining DH, Chedid VG, Farraye FA, Faubion WA Jr, Johnson AM, Kane SV, Kisiel JB, Malik TA, Papadakis KA, Pardi DS, Picco MF, Raffals LE, Schroeder KW, Tremaine WJ, Coelho-Prabhu N. Vulvar Crohn's Disease: Clinical Features and Outcomes. Am J Gastroenterol. 2021 Nov 1; 116 (11):2296-2299
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  44. Kamboj AK, Chandrasekhara V, Simonetto DA, Raffals LE. How We Did It: Virtual Interviews With an Eye Toward the Future. Am J Gastroenterol. 2021 Oct 1; 116 (10):1972-1975
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  45. Rabinowitz LG, Grinspan LT, Zylberberg HM, Dixon R, David YN, Aroniadis OC, Chiang A, Christie J, Fayad NF, Ha C, Harris LA, Ko CW, Kolb J, Kwah J, Lee L, Lieberman D, Raffals LE, Rex DK, Shah SC, Siddiqui UD, Smith MS, Wallace M, Williams R, Woods K, Crowe SE, Kumta NA, Kim MK, Greenwald DA. Survey Finds Gender Disparities Impact Both Women Mentors and Mentees in Gastroenterology. Am J Gastroenterol. 2021 Sep 1; 116 (9):1876-1884
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  46. Lui J, Ramos GP, Codipilly DC, Katzka D, Raffals LE. The Use of Biologics for the Treatment of Esophageal Crohn Disease. Inflamm Bowel Dis. 2021 Aug 19; 27 (9):1544-1547
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  47. Abd El Aziz MA, Perry WRG, Grass F, Merchea A, Raffals LE, Mathis KL, Behm KT. The extent of colorectal resection and short-term outcomes in patients with ulcerative colitis. Updates Surg. 2021 Aug; 73 (4):1429-1434 Epub 2021 Mar 30
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  48. Ramos GP, Dimopoulos C, McDonald NM, Janssens LP, Hung KW, Proctor D, Ruggiero E, Kane S, Bruining DH, Faubion WA, Raffals LE, Loftus EV, Al-Bawardy B. The Impact of Vedolizumab on Pre-Existing Extraintestinal Manifestations of Inflammatory Bowel Disease: A Multicenter Study. Inflamm Bowel Dis. 2021 Jul 27; 27 (8):1270-1276
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  49. Vasudevan A, Bruining DH, Loftus EV Jr, Faubion W, Ehman EC, Raffals L. Approach to medical therapy in perianal Crohn's disease. World J Gastroenterol. 2021 Jul 7; 27 (25):3693-3704
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  50. Ramos GP, Al-Bawardy B, Braga Neto MB, Bledsoe AC, Quinn KP, Heron V, Willrich MAV, Johnson A, Chedid VG, Coelho-Prabhu N, Kisiel JB, Papadakis KA, Pardi D, Kane S, Tremaine WJ, Raffals L, Bruining DH, Faubion WA, Harmsen WS, Loftus EV Jr. Certolizumab Trough Levels and Antibodies in Crohn Disease: A Single-Center Experience. Crohns Colitis 360. 2021 Jul; 3 (3):otab019 Epub 2021 May 17
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  51. Braga Neto MB, Ramos GP, Loftus EV Jr, Faubion WA, Raffals LE. Use of Immune Checkpoint Inhibitors in Patients With Pre-established Inflammatory Bowel Diseases: Retrospective Case Series. Clin Gastroenterol Hepatol. 2021 Jun; 19 (6):1285-1287.e1 Epub 2020 June 19
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  52. Coelho-Prabhu N, Bruining DH, Faubion WA, Kane SV, Kisiel JB, Papadakis KA, Pardi DS, Raffals LE, Schroeder KW, Tremaine WJ, Fruth K, Harmsen WS, Loftus EV. A 1-Year Cross-sectional Inflammatory Bowel Disease Surveillance Colonoscopy Cohort Comparing High-definition White Light Endoscopy and Chromoendoscopy. Inflamm Bowel Dis. 2021 Apr 15; 27 (5):594-602
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  53. Kwapisz L, Raffals LE, Bruining DH, Pardi DS, Tremaine WJ, Kane SV, Papadakis KA, Coelho-Prabhu N, Kisiel JB, Heron V, Faubion WA, Loftus EV Jr. Combination Biologic Therapy in Inflammatory Bowel Disease: Experience From a Tertiary Care Center. Clin Gastroenterol Hepatol. 2021 Mar; 19 (3):616-617 Epub 2020 Feb 14
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  54. Kamboj AK, Raffals LE, Martin JA, Chandrasekhara V. Virtual Interviews During the COVID-19 Pandemic: A Survey of Advanced Endoscopy Fellowship Applicants and Programs. Tech Innov Gastrointest Endosc. 2021; 23 (2):159-168 Epub 2021 Feb 07
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  55. Boeve BF, Burke JR, Carrasquillo MM, Dickson DW, Harrell LE, Miller CA, Parisi JE, Younkin SG, Yu L, Yu CE, Kunkle BW, Schmidt M, Klein HU, Naj AC, Hamilton-Nelson KL, Larson EB, Evans DA, De Jager PL, Crane PK, Buxbaum JD, Ertekin-Taner N, Barnes LL, Fallin MD, Manly JJ, Go RCP, Obisesan TO, Kamboh MI, Bennett DA, Hall KS, Goate AM, Foroud TM, Martin ER, Wang LS, Byrd GS, Farrer LA, Haines JL, Schellenberg GD, Mayeux R, Pericak-Vance MA, Reitz C, Graff-Radford NR, Martinez I, Ayodele T, Logue MW, Cantwell LB, Jean-Francois M, Kuzma AB, Adams LD, Vance JM, Cuccaro ML, Chung J, Mez J, Lunetta KL, Jun GR, Lopez OL, Hendrie HC, Reiman EM, Kowall NW, Leverenz JB, Small SA, Levey AI, Golde TE, Saykin AJ, Starks TD, Albert MS, Hyman BT, Petersen RC, Sano M, Wisniewski T, Vassar R, Kaye JA, Henderson VW, DeCarli C, LaFerla FM, Brewer JB, Miller BL, Swerdlow RH, Van Eldik LJ, Paulson HL, Trojanowski JQ, Chui HC, Rosenberg RN, Craft S, Grabowski TJ, Asthana S, Morris JC, Strittmatter SM, Kukull WA, Writing Group for the Alzheimer's Disease Genetics Consortium (ADGC). Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis. JAMA Neurol. 2021 Jan 1; 78 (1):102-113
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  56. Quinn KP, Raffals LE. An Update on the Medical Management of Inflammatory Pouch Complications. Am J Gastroenterol. 2020 Sep; 115 (9):1439-1450
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  57. Marshall AL, Thompson CA, Cullen MW, Raffals LE, Oxentenko AS. Medical Education Interest, Exposure, and Career Planning in Subspecialty Trainees. Med Sci Educ. 2020 Sep; 30 (3):1011-1014 Epub 2020 June 10
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  58. Dulai PS, Raffals LE, Hudesman D, Chiorean M, Cross R, Ahmed T, Winter M, Chang S, Fudman D, Sadler C, Chiu EL, Ross FL, Toups G, Murad MH, Sethuraman K, Holm JR, Guilliod R, Levine B, Buckey JC Jr, Siegel CA. A phase 2B randomised trial of hyperbaric oxygen therapy for ulcerative colitis patients hospitalised for moderate to severe flares. Aliment Pharmacol Ther. 2020 Sep; 52 (6):955-963 Epub 2020 Aug 03
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  59. Cohen BL, Gallinger ZR, Ha C, Holubar SD, Hou JK, Kinnucan J, Mahadevan U, Moss AC, Raffals LE, Regueiro M, Szigethy E, Wolf D, Dubinsky MC, Patel A, Shah BJ, Ehrlich OG, Hanauer SB. Development of Entrustable Professional Activities for Advanced Inflammatory Bowel Disease Fellowship Training in the United States. Inflamm Bowel Dis. 2020 Aug 20; 26 (9):1291-1305
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  60. Bies M, Vijayvargiya P, Raffals L. Submucosal Vascular Malformation as the Cause of Recurrent Obscure Bleed. Clin Gastroenterol Hepatol. 2020 Aug; 18 (9):e106 Epub 2019 May 14
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  61. Barnes EL, Raffals L, Long MD, Syal G, Kayal M, Ananthakrishnan A, Cohen B, Pekow J, Deepak P, Colombel JF, Herfarth HH, Sandler RS. Disease and Treatment Patterns Among Patients With Pouch-related Conditions in a Cohort of Large Tertiary Care Inflammatory Bowel Disease Centers in the United States. Crohns Colitis 360. 2020 Jul; 2 (3):otaa039 Epub 2020 July 24
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  62. Braga Neto MB, Gregory MH, Ramos GP, Bazerbachi F, Bruining DH, Abu Dayyeh BK, Kushnir VM, Raffals LE, Ciorba MA, Loftus EV, Deepak P. Impact of Bariatric Surgery on the Long-term Disease Course of Inflammatory Bowel Disease. Inflamm Bowel Dis. 2020 Jun 18; 26 (7):1089-1097
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  63. Rajan E, Martinez M, Gorospe E, Al Bawardy B, Dobashi A, Mara KC, Hansel SL, Bruining DH, Murray JA, Leggett CL, Nehra V, Iyer PG, Pasha SF, Leighton JA, Shiff AD, Gurudu SR, Raffals LE, Lavey C, Katzka DA, Chen CH. Prospective multicenter study to evaluate capsule endoscopy competency using a validated assessment tool. Gastrointest Endosc. 2020 May; 91 (5):1140-1145 Epub 2019 Dec 26
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  64. Wang MH, Mousa OY, Friton JJ, Raffals LE, Leighton JA, Pasha SF, Picco MF, Cushing KC, Monroe K, Nix BD, Newberry RD, Faubion WA. Unique Phenotypic Characteristics and Clinical Course in Patients With Ulcerative Colitis and Primary Sclerosing Cholangitis: A Multicenter US Experience. Inflamm Bowel Dis. 2020 Apr 11; 26 (5):774-779
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  65. Eckmann JD, Chedid V, Quinn KP, Bonthu N, Nehra V, Raffals LE. De Novo Colitis Associated With Rituximab in 21 Patients at a Tertiary Center. Clin Gastroenterol Hepatol 2020 Jan; 18 (1):252-253 Epub 2019 Mar 21
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  66. Jawoosh M, Haffar S, Deepak P, Meyers A, Lightner AL, Larson DW, Raffals LH, Murad MH, Buttar N, Bazerbachi F. Volvulus of the ileal pouch-anal anastomosis: a meta-narrative systematic review of frequency, diagnosis, and treatment outcomes. Gastroenterol Rep (Oxf). 2019 Dec; 7 (6):403-410 Epub 2019 Sept 17
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  67. Park SH, Al-Bawardy B, Aniwan S, Kane SV, Coelho-Prabhu N, Papadakis KA, Kisiel JB, Bruining DH, Faubion WA, Raffals LE, Pardi DS, Tremaine WJ, Stephens MC, Tung J, Khanna S, Willrich, Loftus EV. Distinct cutoff values of adalimumab trough levels are associated with different therapeutic outcomes in patients with inflammatory bowel disease. Crohn's & Colitis 360. 2019; 1(3):otz047.
  68. Lightner AL, McKenna NP, Alsughayer A, Harmsen WS, Taparra K, Parker ME, Raffals LE, Loftus EV Jr. Biologics and 30-Day Postoperative Complications After Abdominal Operations for Crohn's Disease: Are There Differences in the Safety Profiles? Dis Colon Rectum. 2019 Nov; 62 (11):1352-1362
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  69. Lightner AL, McKenna NP, Alsughayer A, Loftus EV Jr, Raffals LE, Faubion WA, Moir C. Anti-TNF biologic therapy does not increase postoperative morbidity in pediatric Crohn's patients. J Pediatr Surg. 2019 Oct; 54 (10):2162-2165 Epub 2019 Jan 18
    View PubMed
  70. Wang , Mousa OY, Friton JJ, Raffals LE, Leighton JA, Pasha SF, Picco MF, Cushing KC, Monroe K, Nix BD, Newberry RD, Faubion WA. Unique Phenotypic Characteristics and Clinical Course in Patients With Ulcerative Colitis and Primary Inflamm Bowel Dis. 2019.
  71. Gregory M, Weaver KN, Hoversten P, Hicks SB, Patel D, Ciorba MA, Gutierrez AM, Beniwal-Patel P, Palam S, Syal G, Herfarth HH, Christophi G, Raffals L, Barnes EL, Deepak P. Efficacy of Vedolizumab for Refractory Pouchitis of the Ileo-anal Pouch: Results From a Multicenter US Cohort. Inflamm Bowel Dis. 2019 Aug 20; 25 (9):1569-1576
    View PubMed
  72. Quinn KP, Prothero BL, Russell JM, Hegge RJ, von AG, Larson PA, Christofferson SN, Smyrk TC, Mathis KL, Goenka AH, Sheedy SP, Bruining DH, Fletcher JG, Loftus EV, Raffals LE. Impact of multidisciplinary eBoard on the management of patients with complex inflammatory bowel disease. Crohn's & Colitis 360. 2019; 1(2):otz013.
  73. Lightner AL, Grass F, Alsughayer A, Petersen MM, Raffals LE, Loftus EV. Postoperative outcomes in ustekinumab-treated patients undergoing abdominal operations for Crohn's disease: single-center series. Crohn's & Colitis 360. 2019; 1(2):otz018.
  74. Wang MH, Friton JJ, Raffals LE, Leighton JA, Pasha SF, Picco MF, Cushing KC, Monroe K, Nix BD, Newberry RD, Faubion WA. Novel Genetic Risk Variants Can Predict Anti-TNF Agent Response in Patients With Inflammatory Bowel Disease. J Crohns Colitis. 2019 Aug 14; 13 (8):1036-1043
    View PubMed
  75. Aniwan S, Bruining DH, Park SH, Al-Bawardy B, Kane SV, Coelho Prabhu N, Kisiel JB, Raffals LE, Papadakis KA, Pardi DS, Tremaine WJ, Loftus EV Jr. The Combination of Patient-Reported Clinical Symptoms and an Endoscopic Score Correlates Well with Health-Related Quality of Life in Patients with Ulcerative Colitis. J Clin Med. 2019 Aug 5; 8 (8) Epub 2019 Aug 05
    View PubMed
  76. Papamichael K, Cheifetz AS, Melmed GY, Irving PM, Vande Casteele N, Kozuch PL, Raffals LE, Baidoo L, Bressler B, Devlin SM, Jones J, Kaplan GG, Sparrow MP, Velayos FS, Ullman T, Siegel CA. Appropriate Therapeutic Drug Monitoring of Biologic Agents for Patients With Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol 2019 Aug; 17 (9):1655-1668.e3 Epub 2019 Mar 27
    View PubMed
  77. Sparrow MP, Melmed GY, Devlin S, Kozuch P, Raffals L, Loftus EV Jr, Rubin DT, Spiegel B, Baidoo L, Bressler B, Cheifetz A, Irving P, Jones J, Kaplan GG, Velayos F, Siegel CA. De-escalating medical therapy in Crohn's disease patients who are in deep remission: a RAND appropriateness panel GastroHep. 2019; 1(3):108-117.
  78. Muniz Pedrogo DA, Chen J, Hillmann B, Jeraldo P, Al-Ghalith G, Taneja V, Davis JM 3rd, Knights D, Nelson H, Faubion WA, Raffals L, Kashyap PC. An Increased Abundance of Clostridiaceae Characterizes Arthritis in Inflammatory Bowel Disease and Rheumatoid Arthritis: A Cross-sectional Study. Inflamm Bowel Dis. 2019 Apr 11; 25 (5):902-913
    View PubMed
  79. Raffals LE, Nguyen GC, Rubin DT. Switching Between Biologics and Biosimilars in Inflammatory Bowel Disease. Clin Gastroenterol Hepatol. 2019 Apr; 17 (5):818-823 Epub 2018 Sept 07
    View PubMed
  80. Weaver KN, Gregory M, Syal G, Hoversten P, Hicks SB, Patel D, Christophi G, Beniwal-Patel P, Isaacs KL, Raffals L, Deepak P, Herfarth HH, Barnes EL. Ustekinumab Is Effective for the Treatment of Crohn's Disease of the Pouch in a Multicenter Cohort. Inflamm Bowel Dis. 2019 Mar 14; 25 (4):767-774
    View PubMed
  81. Quinn KP, Lightner AL, Faubion WA, Raffals LE. A Comprehensive Approach to Pouch Disorders. Inflamm Bowel Dis. 2019 Feb 21; 25 (3):460-471
    View PubMed
  82. Al-Bawardy B, Ramos GP, Willrich MAV, Jenkins SM, Park SH, Aniwan S, Schoenoff SA, Bruining DH, Papadakis KA, Raffals L, Tremaine WJ, Loftus EV. Vedolizumab Drug Level Correlation With Clinical Remission, Biomarker Normalization, and Mucosal Healing in Inflammatory Bowel Disease. Inflamm Bowel Dis. 2019 Feb 21; 25 (3):580-586
    View PubMed
  83. Lightner AL, Edward V Loftus Jr Loftus, Loftus EV, McKenna NP, Raffals LE. Vedolizumab in the Perioperative Management of Inflammatory Bowel Disease. Curr Drug Targets. 2019; 20 (13):1317-1322
    View PubMed
  84. Ichikawa R, Lamb CA, Eastham-Anderson J, Scherl A, Raffals L, Faubion WA, Bennett MR, Long AK, Mansfield JC, Kirby JA, Keir ME. AlphaE Integrin Expression Is Increased in the Ileum Relative to the Colon and Unaffected by Inflammation. J Crohns Colitis. 2018 Nov 9; 12 (10):1191-1199
    View PubMed
  85. Melmed GY, Kaplan GG, Sparrow MP, Velayos FS, Baidoo L, Bressler B, Cheifetz AS, Devlin SM, Irving PM, Jones J, Kozuch PL, Raffals LE, Siegel CA. Appropriateness of Combination Therapy for Patients With Inflammatory Bowel Diseases: One Size Still Does Not Fit All. Clin Gastroenterol Hepatol. 2018 Nov; 16 (11):1829-1831 Epub 2018 Mar 02
    View PubMed
  86. Dulai PS, Buckey JC Jr, Raffals LE, Swoger JM, Claus PL, O'Toole K, Ptak JA, Gleeson MW, Widjaja CE, Chang JT, Adler JM, Patel N, Skinner LA, Haren SP, Goldby-Reffner K, Thompson KD, Siegel CA. Hyperbaric oxygen therapy is well tolerated and effective for ulcerative colitis patients hospitalized for moderate-severe flares: a phase 2A pilot multi-center, randomized, double-blind, sham-controlled trial. Am J Gastroenterol. 2018 Oct; 113 (10):1516-1523 Epub 2018 Feb 16
    View PubMed
  87. Malikowski T, Mahmood M, Smyrk T, Raffals L, Nehra V. Tuberculosis of the gastrointestinal tract and associated viscera. J Clin Tuberc Other Mycobact Dis. 2018 Aug; 12:1-8 Epub 2018 Apr 14
    View PubMed
  88. Tse CS, Loftus EV Jr, Raffals LE, Gossard AA, Lightner AL. Effects of vedolizumab, adalimumab and infliximab on biliary inflammation in individuals with primary sclerosing cholangitis and inflammatory bowel disease. Aliment Pharmacol Ther. 2018 Jul; 48 (2):190-195 Epub 2018 May 28
    View PubMed
  89. Hansel SL, McCurdy JD, Barlow JM, Fidler J, Fletcher JG, Becker B, Prabhu NC, Faubion WA, Hanson KA, Kane SV, Kisiel JB, Loftus EV Jr, Papadakis KA, Pardi DS, Raffals LE, Schoenoff S, Tremaine WJ, Bruining DH. Clinical Benefit of Capsule Endoscopy in Crohn's Disease: Impact on Patient Management and Prevalence of Proximal Small Bowel Involvement. Inflamm Bowel Dis. 2018 Jun 8; 24 (7):1582-1588
    View PubMed
  90. Patel P, Yarur A, Dalal S, Sakuraba A, Rubin DT, Hanauer SB, Hanan I, Raffals LH, Cohen RD, Pekow J. Clinical Response and Complications are not Associated with Drug Levels in Patients with Severe Ulcerative Colitis on IV Cyclosporine Induction Therapy. Inflamm Bowel Dis. 2018 May 18; 24 (6):1291-1297
    View PubMed
  91. Mouchli MA, Singh S, Boardman L, Bruining DH, Lightner AL, Rosen CB, Heimbach JK, Hasan B, Poterucha JJ, Watt KD, Kane SV, Raffals LE, Loftus EV. Natural History of Established and De Novo Inflammatory Bowel Disease After Liver Transplantation for Primary Sclerosing Cholangitis. Inflamm Bowel Dis. 2018 Apr 23; 24 (5):1074-1081
    View PubMed
  92. Hanada Y, Khanna S, Loftus EV Jr, Raffals LE, Pardi DS. Non-Clostridium difficile Bacterial Infections Are Rare in Patients With Flares of Inflammatory Bowel Disease. Clin Gastroenterol Hepatol. 2018 Apr; 16 (4):528-533 Epub 2017 Oct 14
    View PubMed
  93. Lightner AL, McKenna NP, Tse CS, Hyman N, Smith R, Ovsepyan G, Fleshner P, Crowell K, Koltun W, Ferrante M, D'Hoore A, Lauwers N, Verstockt B, Spinelli A, DiCandido F, Raffals LE, Mathis KL, Loftus EV Jr. Postoperative Outcomes in Ustekinumab-Treated Patients Undergoing Abdominal Operations for Crohn's Disease. J Crohns Colitis. 2018 Mar 28; 12 (4):402-407
    View PubMed
  94. Braga Neto MB, Gregory M, Ramos GP, Piovezani Ramos G, Loftus EV Jr, Ciorba MA, Bruining DH, Bazerbachi F, Abu Dayyeh BK, Kushnir VM, Shah M, Collazo-Clavell ML, Raffals LE, Deepak P. De-novo Inflammatory Bowel Disease After Bariatric Surgery: A Large Case Series. J Crohns Colitis. 2018 Mar 28; 12 (4):452-457
    View PubMed
  95. Lightner AL, McKenna NP, Tse CS, Raffals LE, Loftus EV Jr, Mathis KL. Postoperative outcomes in vedolizumab-treated Crohn's disease patients undergoing major abdominal operations. Aliment Pharmacol Ther. 2018 Mar; 47 (5):573-580 Epub 2017 Dec 18
    View PubMed
  96. Aniwan S, Tremaine WJ, Raffals LE, Kane SV, Loftus EV Jr. Antibiotic Use and New-Onset Inflammatory Bowel Disease in Olmsted County, Minnesota: A Population-Based Case-Control Study. J Crohns Colitis. 2018 Jan 24; 12 (2):137-144
    View PubMed
  97. Kotze PG, Ma C, Mckenna N, Almutairdi A, Kaplan GG, Raffals LE, Loftus EV Jr, Panaccione R, Lightner AL. Vedolizumab and early postoperative complications in nonintestinal surgery: a case-matched analysis. Therap Adv Gastroenterol. 2018; 11:1756284818783614 Epub 2018 June 21
    View PubMed
  98. Kochar B, Barnes EL, Long MD, Cushing KC, Galanko J, Martin CF, Raffals LE, Sandler RS. Depression Is Associated With More Aggressive Inflammatory Bowel Disease. Am J Gastroenterol. 2018 Jan; 113 (1):80-85 Epub 2017 Nov 14
    View PubMed
  99. Tse CS, Deepak P, Smyrk TC, Raffals LE. Isolated Acute Terminal Ileitis Without Preexisting Inflammatory Bowel Disease Rarely Progresses to Crohn's Disease. Dig Dis Sci. 2017 Dec; 62 (12):3557-3562 Epub 2017 Oct 24
    View PubMed
  100. Lightner AL, McKenna NP, Moncrief S, Pemberton JH, Raffals LE, Mathis KL. Surgical Outcomes in Vedolizumab-Treated Patients with Ulcerative Colitis. Inflamm Bowel Dis. 2017 Dec; 23 (12):2197-2201
    View PubMed
  101. Lightner AL, Fletcher JG, Pemberton JH, Mathis KL, Raffals LE, Smyrk T. Crohn's Disease of the Pouch: A True Diagnosis or an Oversubscribed Diagnosis of Exclusion? Dis Colon Rectum. 2017 Nov; 60 (11):1201-1208
    View PubMed
  102. Khanna S, Raffals LE. The Microbiome in Crohn's Disease: Role in Pathogenesis and Role of Microbiome Replacement Therapies. Gastroenterol Clin North Am. 2017 Sep; 46 (3):481-492 Epub 2017 July 19
    View PubMed
  103. Quinn KP, Tse CS, Lightner AL, Pendegraft RS, Enders FT, Raffals LE. Nonrelaxing Pelvic Floor Dysfunction Is an Underestimated Complication of Ileal Pouch-Anal Anastomosis. Clin Gastroenterol Hepatol. 2017 Aug; 15 (8):1242-1247 Epub 2017 Mar 01
    View PubMed
  104. Kochar B, Long MD, Galanko J, Raffals LE, Ananthakrishnan A, Sandler RS. Inflammatory Bowel Disease is Similar in Patients with Older Onset and Younger Onset. Inflamm Bowel Dis. 2017 Jul; 23 (7):1187-1194
    View PubMed
  105. Ananthakrishnan AN, Sakuraba A, Barnes EL, Pekow J, Raffals L, Long MD, Sandler RS. The benefit of combination therapy depends on disease phenotype and duration in Crohn's disease. Aliment Pharmacol Ther. 2017 Jul; 46 (2):162-168 Epub 2017 May 03
    View PubMed
  106. Lightner AL, Tse CS, Quinn K, Bergquist JR, Enders F, Pendegraft R, Khanna S, Raffals L. Preoperative Clostridium difficile Infection Does Not Affect Pouch Outcomes in Patients with Ulcerative Colitis Who Undergo Ileal Pouch-anal Anastomosis. Inflamm Bowel Dis. 2017 Jul; 23 (7):1195-1201
    View PubMed
  107. Lightner AL, Mathis KL, Dozois EJ, Hahnsloser D, Loftus EV Jr, Raffals LE, Pemberton JH. Results at Up to 30 Years After Ileal Pouch-Anal Anastomosis for Chronic Ulcerative Colitis. Inflamm Bowel Dis. 2017 May; 23 (5):781-790
    View PubMed
  108. Huang Y, Dalal S, Antonopoulos D, Hubert N, Raffals LH, Dolan K, Weber C, Messer JS, Jabri B, Bendelac A, Eren AM, Rubin DT, Sogin M, Chang EB. Early Transcriptomic Changes in the Ileal Pouch Provide Insight into the Molecular Pathogenesis of Pouchitis and Ulcerative Colitis. Inflamm Bowel Dis. 2017 Mar; 23 (3):366-378
    View PubMed
  109. Lightner AL, Raffals LE, Mathis KL, Cima RR, Tse CS, Pemberton JH, Dozois EJ, Loftus EV. Postoperative Outcomes in Vedolizumab-Treated Patients Undergoing Abdominal Operations for Inflammatory Bowel Disease. J Crohns Colitis. 2017 Feb; 11 (2):185-190 Epub 2016 Aug 19
    View PubMed
  110. Vineis JH, Ringus DL, Morrison HG, Delmont TO, Dalal S, Raffals LH, Antonopoulos DA, Rubin DT, Eren AM, Chang EB, Sogin ML. Patient-Specific Bacteroides Genome Variants in Pouchitis. mBio. 2016 Nov 15; 7 (6)
    View PubMed
  111. Kottschade L, Brys A, Peikert T, Ryder M, Raffals L, Brewer J, Mosca P, Markovic S, Midwest Melanoma Partnership. A multidisciplinary approach to toxicity management of modern immune checkpoint inhibitors in cancer therapy. Melanoma Res. 2016 Oct; 26 (5):469-80
    View PubMed
  112. Quinn KP, Lightner AL, Pendegraft RS, Enders FT, Boardman LA, Raffals LE. Pouchitis Is a Common Complication in Patients With Familial Adenomatous Polyposis Following Ileal Pouch-Anal Anastomosis. Clin Gastroenterol Hepatol. 2016 Sep; 14 (9):1296-301 Epub 2016 Apr 13
    View PubMed
  113. Melmed GY, Irving PM, Jones J, Kaplan GG, Kozuch PL, Velayos FS, Baidoo L, Sparrow MP, Bressler B, Cheifetz AS, Devlin SM, Raffals LE, Vande Casteele N, Mould DR, Colombel JF, Dubinsky M, Sandborn WJ, Siegel CA. Appropriateness of Testing for Anti-Tumor Necrosis Factor Agent and Antibody Concentrations, and Interpretation of Results. Clin Gastroenterol Hepatol. 2016 Sep; 14 (9):1302-9 Epub 2016 May 14
    View PubMed
  114. Raffals LE, Chang EB. Navigating the Microbial Basis of Inflammatory Bowel Diseases: Seeing the Light at the End of the Tunnel. Gut Liver. 2016 Jul 15; 10 (4):502-8
    View PubMed
  115. Devlin SM, Melmed GY, Irving PM, Rubin DT, Kornbluth A, Kozuch PL, Raffals LE, Velayos FS, Sparrow MP, Baidoo L, Bressler B, Cheifetz AS, Jones J, Kaplan GG, Siegel CA. Recommendations for Quality Colonoscopy Reporting for Patients with Inflammatory Bowel Disease: Results from a RAND Appropriateness Panel. Inflamm Bowel Dis 2016 Jun; 22 (6):1418-24
    View PubMed
  116. Ward MA, Pierre JF, Leal RF, Huang Y, Shogan B, Dalal SR, Weber CR, Leone VA, Musch MW, An GC, Rao MC, Rubin DT, Raffals LE, Antonopoulos DA, Sogin ML, Hyman NH, Alverdy JC, Chang EB. Insights into the pathogenesis of ulcerative colitis from a murine model of stasis-induced dysbiosis, colonic metaplasia, and genetic susceptibility. Am J Physiol Gastrointest Liver Physiol. 2016 Jun 1; 310 (11):G973-88 Epub 2016 Apr 14
    View PubMed
  117. Jones JL, Kaplan GG, Peyrin-Biroulet L, Baidoo L, Devlin S, Melmed GY, Tanyingoh D, Raffals L, Irving P, Kozuch P, Sparrow M, Velayos F, Bressler B, Cheifetz A, Colombel JF, Siegel CA. Effects of Concomitant Immunomodulator Therapy on Efficacy and Safety of Anti-Tumor Necrosis Factor Therapy for Crohn's Disease: A Meta-analysis of Placebo-controlled Trials. Clin Gastroenterol Hepatol. 2015 Dec; 13 (13):2233-40.e1-2; quiz e177-8 Epub 2015 June 30
    View PubMed
  118. De Felice KM, Katzka DA, Raffals LE. Crohn's Disease of the Esophagus: Clinical Features and Treatment Outcomes in the Biologic Era. Inflamm Bowel Dis. 2015 Sep; 21 (9):2106-13
    View PubMed
  119. De Felice KM, Gupta A, Rakshit S, Khanna S, Kottschade LA, Finnes HD, Papadakis KA, Loftus EV Jr, Raffals LE, Markovic SN. Ipilimumab-induced colitis in patients with metastatic melanoma. Melanoma Res. 2015 Aug; 25 (4):321-7
    View PubMed
  120. Ananthakrishnan AN, Kwon J, Raffals L, Sands B, Stenson WF, McGovern D, Kwon JH, Rheaume RL, Sandler RS. Variation in treatment of patients with inflammatory bowel diseases at major referral centers in the United States. Clin Gastroenterol Hepatol. 2015 Jun; 13 (6):1197-200 Epub 2014 Nov 21
    View PubMed
  121. Tabibian A, Tabibian JH, Beckman LJ, Raffals LL, Papadakis KA, Kane SV. Predictors of health-related quality of life and adherence in Crohn's disease and ulcerative colitis: implications for clinical management. Dig Dis Sci. 2015 May; 60 (5):1366-74 Epub 2015 Jan 06
    View PubMed
  122. Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, Tschanz JT, Munger RG, Corcoran CD, Rogaeva E, Lin CF, Dombroski BA, Cantwell LB, Partch A, Valladares O, Hakonarson H, St George-Hyslop P, Green RC, Goate AM, Foroud TM, Carney RM, Larson EB, Behrens TW, Kauwe JS, Haines JL, Farrer LA, Pericak-Vance MA, Mayeux R, Schellenberg GD, Albert MS, Albin RL, Apostolova LG, Arnold SE, Barber R, Barmada M, Barnes LL, Beach TG, Becker JT, Beecham GW, Beekly D, Bennett DA, Bigio EH, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Burke JR, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carroll SL, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, DeKosky ST, Demirci FY, Dick M, Dickson DW, Duara R, Ertekin-Taner N, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Glass JD, Graff-Radford NR, Growdon JH, Hamilton RL, Hamilton-Nelson KL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jarvik GP, Jicha GA, Jin LW, Jun G, Jun G, Kamboh MI, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lopez OL, Lunetta KL, Lyketsos CG, Mack WJ, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam WM, Miller BL, Miller CA, Miller JW, Montine TJ, Morris JC, Murrell JR, Olichney JM, Parisi JE, Perry W, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Wishnek S, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu L, Alzheimer's Disease Genetics Consortium//National Institute on Aging-Late-Onset Alzheimer's Disease (NIA-LOAD) Family Study. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. JAMA Neurol. 2015 Feb; 72 (2):209-16
    View PubMed
  123. De Felice KM, Novotna M, Enders FT, Faubion WA, Tremaine WJ, Kantarci OH, Raffals LE. Idiopathic inflammatory demyelinating disease of the central nervous system in patients with inflammatory bowel disease: retrospective analysis of 9095 patients. Aliment Pharmacol Ther. 2015 Jan; 41 (1):99-107 Epub 2014 Oct 27
    View PubMed
  124. Batista D, Raffals L. Role of intestinal bacteria in the pathogenesis of pouchitis. Inflamm Bowel Dis. 2014 Aug; 20 (8):1481-6
    View PubMed
  125. Huse1 SM, Young VB, Morrison HG, Antonopoulos DA, Kwon J, Dalal S, Arrieta R, Hubert NA, Shen L, Vineis JH, Koval JC, Sogin ML, Chang EB, Raffals LE. Comparison of brush and biopsy sampling methods of the ileal pouch for assessment of mucosa-associated microbiota of human subjects. Microbiome. Feb 2014; 2(5).
  126. Kane SV, Neis B, Becker BD, Bruining D, Faubion WA, Kisiel J, Loftus EV Jr, Pardi D, Raffals L, Schroeder K, Tremaine WJ. Letter: Effectiveness of split-dose certolizumab pegol for Crohn's disease. Aliment Pharmacol Ther 2013 Dec; 38 (11-12):1412
    View PubMed
  127. McCurdy JD, Loftus EV Jr, Tremaine WJ, Smyrk TC, Bruining DH, Pardi DS, Raffals LE, Kisiel JB, Coelho-Prabhu N, Kane SV, Faubion WA, Papadakis KA. Cytomegalovirus infection of the ileoanal pouch: clinical characteristics and outcomes. Inflamm Bowel Dis. 2013 Oct; 19 (11):2394-9
    View PubMed
  128. Hoentjen F, Seinen ML, Hanauer SB, de Boer NK, Rubin DT, Bouma G, Harrell LE, van Bodegraven AA. Safety and effectiveness of long-term allopurinol-thiopurine maintenance treatment in inflammatory bowel disease. Inflamm Bowel Dis. 2013 Feb; 19(2):363-9.
    View PubMed
  129. Vital M, Young VB, Raffals LE, Huse S, Schloss P, Dai D, Brulc JM, Antonopoulos DA, Arrieta R, Kwon J, Reddy G, Hubert N, Dalal S, Morrison H, Eren MA, Schmidt TM, Sogin M, Chang EB, Tiedje J. A gene-targeted approach to investigate the intestinal butyrate-producing bacterial community. Microbiom. 2013; 1(8).
  130. Young VB, Raffals LH, Huse S, Schloss PD, Vital M, Dai D, Brulc JM, Antonopoulos DA, Arrieta R, Kwon J, Reddy G, Hubert N, Dalal S, Morrison H, Eren MA, Schmidt TM, Tiedje J, Sogin M, Chang EB, Mitchell SL. Multiphasic Analysis of the Temporal Development of the Distal Gut Microbiota in Patients Following Ileal Pouch-Anal Anastomosis. Microbiome. 2013; 1(9).
  131. Raffals L, Camilleri M. Visceral hypersensitivity and IBD. Inflammatory Bowel Disease Monitor. 2013; 13(3):85-91.
  132. Cheifetz AS, Melmed GY, Spiegel B, Talley J, Devlin SM, Raffals L, Irving PM, Jones J, Kaplan GG, Kozuch P, Sparrow M, Velayos F, Baidoo L, Bressler B, Siegel CA. Setting priorities for comparative effectiveness research in inflammatory bowel disease: results of an international provider survey, expert RAND panel, and patient focus groups. Inflamm Bowel Dis. 2012 Dec; 18(12):2294-300. Epub 2012 Feb 15.
    View PubMed
  133. Cohen RD, Lewis JR, Turner H, Harrell LE, Hanauer SB, Rubin DT. Predictors of adalimumab dose escalation in patients with Crohn's disease at a tertiary referral center. Inflamm Bowel Dis. 2012 Jan; 18(1):10-6. Epub 2011 Mar 31.
    View PubMed
  134. Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, Evans D, Schneider JA, Carrasquillo MM, Ertekin-Taner N, Younkin SG, Cruchaga C, Kauwe JS, Nowotny P, Kramer P, Hardy J, Huentelman MJ, Myers AJ, Barmada MM, Demirci FY, Baldwin CT, Green RC, Rogaeva E, St George-Hyslop P, Arnold SE, Barber R, Beach T, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Carlson CS, Carney RM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cotman CW, Cummings JL, DeCarli C, DeKosky ST, Diaz-Arrastia R, Dick M, Dickson DW, Ellis WG, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Johnson N, Karlawish J, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Lah JJ, Levey AI, Lieberman AP, Lopez OL, Mack WJ, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Parisi JE, Perl DP, Peskind E, Petersen RC, Poon WW, Quinn JF, Rajbhandary RA, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosenberg RN, Sano M, Schneider LS, Seeley W, Shelanski ML, Slifer MA, Smith CD, Sonnen JA, Spina S, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL, Cantwell LB, Dombroski BA, Beekly D, Lunetta KL, Martin ER, Kamboh MI, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet. 2011 May; 43 (5):436-41 Epub 2011 Apr 03
    View PubMed
  135. Harrell LE, Wang Y, Antonopoulos D, Young V, Lichtenstein GL, Huang Y, Hanauer S, Chang E. Standard colonic lavage alters the natural state of mucosal-associated microbiota in the human colon. PLOS. 2011; 7(2):e32545.
  136. Wang Y, Antonopoulos DA, Zhu X, Harrell L, Hanan I, Alverdy JC, Meyer F, Musch MW, Young VB, Chang EB. Laser capture microdissection and metagenomic analysis of intact mucosa-associated microbial communities of human colon. Appl Microbiol Biotechnol. 2010 Dec; 88(6):1333-42. Epub 2010 Oct 08.
    View PubMed
  137. Melmed GY, Spiegel BM, Bressler B, Cheifetz AS, Devlin SM, Harrell LE, Irving PM, Jones J, Kaplan GG, Kozuch PL, Velayos FS, Baidoo L, Sparrow MP, Siegel CA. The appropriateness of concomitant immunomodulators with anti-tumor necrosis factor agents for Crohn's disease: one size does not fit all. Clin Gastroenterol Hepatol. 2010 Aug; 8(8):655-9. Epub 2010 May 06.
    View PubMed
  138. Beniwal P, Harrell LE. The Status of Diagnostic Markers for Inflammatory Bowel Disease. Curr Gastroenterol Rep. 2010.
  139. Khan O, Harrell LE. Fecal Markers of Disease Recurrence in IBD. IBD Monitor.2010;
  140. Farhadi A, Gundlapalli S, Shaikh M, Frantzides C, Harrell L, Kwasny MM, Keshavarzian A. Susceptibility to gut leakiness: a possible mechanism for endotoxaemia in non-alcoholic steatohepatitis. Liver Int. 2008 Aug; 28(7):1026-33. Epub 2008 Apr 07.
    View PubMed
  141. Sparrow MP, Irving PM, Baidoo, Bressler B, Cheifetz AS, Devlin SM, Harrell LE, Jones J, Kozuch PL, Melmed GY, Velayos FS, Siegel CA. Current controversies in Crohn's disease: A roundtable discussion of the BRIDGe group. Gastroenterology and Hepatology. 2008; 4(10):713-20.
  142. Dassopoulos T, Nguyen GC, Bitton A, Bromfield GP, Schumm LP, Wu Y, Elkadri A, Regueiro M, Siemanowski B, Torres EA, Gregory FJ, Kane SV, Harrell LE, Franchimont D, Achkar JP, Griffiths A, Brant SR, Rioux JD, Taylor KD, Duerr RH, Silverberg MS, Cho JH, Steinhart AH. Assessment of reliability and validity of IBD phenotyping within the National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK) IBD Genetics Consortium (IBDGC). Inflamm Bowel Dis. 2007 Aug; 13(8):975-83.
    View PubMed
  143. Harrell LE. Evolving Serological Markers for IBD. Inflamm Bowel Dis Monitor. 2007; 8(2):1-8.
  144. Harrell LE. Advances in IBD. Genotype/Phenotype Correlations in Inflammatory Bowel Disease. Gastroenterology and Hepatology. 2007; 3(7):535-37.
  145. Harrell LE, Rubin DT, Hanauer SB. Fever and right upper quadrant pain in a pregnant woman at 30 weeks' gestation. Nat Clin Pract Gastroenterol Hepatol. 2004 Dec; 1(2):113-6; quiz 1 p following 116.
    View PubMed
  146. Harrell LE, Hanauer SB. Mesalamine derivatives in the treatment of inflammatory bowel disease. Gastroenterology Clinics in North America. 2004; 33(2):303-18.
  147. Angtuaco TL, Reddy SK, Drapkin S, Harrell LE, Howden CW. The utility of urgent colonoscopy in the evaluation of acute lower gastrointestinal tract bleeding: a 2-year experience from a single center. Am J Gastroenterol. 2001 Jun; 96(6):1782-5.
    View PubMed
  148. Blacker D, Haines JL, Rodes L, Terwedow H, Go RC, Harrell LE, Perry RT, Bassett SS, Chase G, Meyers D, Albert MS, Tanzi R. ApoE-4 and age at onset of Alzheimer's disease: the NIMH genetics initiative. Neurology. 1997 Jan; 48 (1):139-47
    View PubMed
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