搜索医生

David S. Knopman, M.D.

  1. Neurologist
预约门诊

出版物

  1. Lavrova A, Pham NTT, Reid RI, Boeve BF, Knopman DS, Petersen RC, Nguyen AT, Ross Reichard R, Dickson DW, Jack CR Jr, Whitwell JL, Josephs KA. Relation of Alzheimer's disease-related TDP-43 proteinopathy to metrics from diffusion tensor imaging (DTI) and neurite orientation dispersion and density imaging (NODDI). Neurobiol Aging. 2025 Jun; 150:97-108 Epub 2025 Mar 08
    View PubMed
  2. Vassilaki M, Aakre JA, Lesnick TG, Kremers WK, Graff-Radford J, Knopman DS, Mosley TH, Windham BG, Griswold ME, Geda YE, Lowe VJ, Jack CR Jr, Petersen RC, Vemuri P. Patterns of Factors in the National Institute on Aging Health Disparities Research Framework Domains and Mild Cognitive Impairment Risk. AJPM Focus. 2025 Jun; 4 (3):100324 Epub 2025 Feb 17
    View PubMed
  3. Shir D, Lee N, McCarter SJ, Ramanan VK, Botha H, Knopman DS, Petersen RC, Boeve BF, Day GS, Graff-Radford NR, Jones DT, Murray ME, Nguyen AT, Reichard RR, Dickson DW, Tajfirouz D, Machulda MM, Whitwell JL, Josephs KA, Graff-Radford J. Longitudinal Evolution of Posterior Cortical Atrophy: Diagnostic Delays, Overlapping Phenotypes, and Clinical Outcomes. Neurology. 2025 May 13; 104 (9):e213559 Epub 2025 Apr 08
    View PubMed
  4. Cannon EJ, Windham BG, Griswold M, Palta P, Knopman DS, Sedaghat S, Lutsey PL. Association of Body Mass Index in Late Life, and Change from Midlife to Late Life, With Incident Dementia in the ARIC Study Participants. Neurology. 2025 May 13; 104 (9):e213534 Epub 2025 Apr 11
    View PubMed
  5. Vuong R, Morrill V, Graff-Radford J, Knopman D, Mosley T, Johansen M, Walker K, Clifford J, Pike J, Schneider A, Gottesman R. Infratentorial Cerebral Microbleeds and Incident Dementia: The ARIC-Neurocognitive Study (P11-13.015). Neurology. 2025 Apr 8; 104 (7_Supplement_1):5001 Epub 2025 Apr 07
    View PubMed
  6. Jones KE, Aakre JA, Castillo AM, Ramanan VK, Kremers WK, Jack CR Jr, Vemuri P, Schwarz CG, Lowe VJ, Knopman DS, Petersen RC, Graff-Radford J, Vassilaki M. Eligibility for donanemab trial in a population-based study of cognitive aging. J Prev Alzheimers Dis. 2025 Apr; 12 (4):100088 Epub 2025 Feb 17
    View PubMed
  7. Planche V, Schindler S, Knopman DS, Frisoni G, Galasko D, Grill JD, Schneider L, Karlawish J, Villain N. The science does not yet support regulatory approval of amyloid-targeting therapies for Alzheimer's disease based solely on biomarker evidence. Alzheimers Dement. 2025 Apr; 21 (4):e70068
    View PubMed
  8. Ghatamaneni S, Coleman C, Shin I, Bruinsma T, Scott N, Lee J, Fang P, Min HK, Moloney CM, Wood AC, Constantopoulos E, Reichard RR, Schwarz CG, Jones DT, Graff-Radford J, Knopman DS, Jack CR Jr, Petersen RC, Dickson DW, Murray ME, Lowe VJ. High resolution autoradiography of [(18)F]MK-6240 and [(18)F]Flortaucipir shows similar neurofibrillary tangle binding patterns preferentially recognizing middling neurofibrillary tangle maturity. Acta Neuropathol. 2025 Mar 14; 149 (1):26
    View PubMed
  9. Morrow CB, Kamath V, Dickerson BC, Eldaief M, Rezaii N, Wong B, McGinnis S, Darby R, Staffaroni AM, Lapid MI, Pascual B, Rojas JC, Masdeu JC, Tsapkini K, Huey ED, Fisher DW, Pantelyat A, Balaji A, Sah E, Litvan I, Rascovsky K, Ghoshal N, Domoto-Reilly K, Kornak J, Onyike CU, ALLFTD Consortium. Neuropsychiatric symptoms cluster and fluctuate over time in behavioral variant frontotemporal dementia. Psychiatry Clin Neurosci. 2025 Mar 13 [Epub ahead of print]
    View PubMed
  10. Wang H, Chang TS, Dombroski BA, Cheng PL, Si YQ, Tucci A, Patil V, Valiente-Banuet L, Li C, Farrell K, Mclean C, Molina-Porcel L, Rajput A, De Deyn PP, Le Bastard N, Gearing M, Donker Kaat L, Van Swieten JC, Dopper E, Ghetti BF, Newell KL, Troakes C, de Yebenes JG, Rabano-Gutierrez A, Meller T, Oertel WH, Respondek G, Stamelou M, Arzberger T, Roeber S, Muller U, Hopfner F, Pastor P, Brice A, Durr A, Le Ber I, Beach TG, Serrano GE, Hazrati LN, Litvan I, Rademakers R, Ross OA, Galasko D, Boxer AL, Miller BL, Seeley WW, Van Deerlin VM, Lee EB, White CL 3rd, Morris HR, de Silva R, Crary JF, Goate AM, Friedman JS, Compta Y, Leung YY, Coppola G, Naj AC, Wang LS, Dalgard C, Dickson DW, Hoglinger GU, Tzeng JY, Geschwind DH, Schellenberg GD, Lee WP, PSP Genetics Study Group. Copy Number Variation and Haplotype Analysis of 17q21.31 Reveals Increased Risk Associated with Progressive Supranuclear Palsy and Gene Expression Changes in Neuronal Cells. Mov Disord. 2025 Mar 8 Epub 2025 Mar 08
    View PubMed
  11. Bermudez C, Lesnick TG, More SS, Ramanan VK, Knopman DS, Rabinstein AA, Cogswell PM, Jack CR Jr, Vemuri P, Petersen RC, Graff-Radford J, Chen JJ. Optical Coherence Tomography Angiography Retinal Imaging Associations With Burden of Small Vessel Disease and Amyloid Positivity in the Brain. J Neuroophthalmol. 2025 Mar 1; 45 (1):63-70 Epub 2024 Aug 01
    View PubMed
  12. Fang M, Hu J, Weiss J, Knopman DS, Albert M, Windham BG, Walker KA, Sharrett AR, Gottesman RF, Lutsey PL, Mosley T, Selvin E, Coresh J. Lifetime risk and projected burden of dementia. Nat Med. 2025 Mar; 31 (3):772-776 Epub 2025 Jan 13
    View PubMed
  13. Ferreira D, Przybelski SA, Lesnick TG, Diaz-Galvan P, Schwarz CG, Murray MM, Dickson DW, Nguyen A, Reichard RR, Senjem ML, Gunter JL, Jack CR Jr, Min PH, Jain MK, Miyagawa T, Forsberg LK, Fields JA, Savica R, Graff-Radford J, Ramanan VK, Jones DT, Botha H, St Louis EK, Knopman DS, Graff-Radford NR, Day GS, Ferman TJ, Kremers WK, Petersen RC, Boeve BF, Lowe VJ, Kantarci K. Longitudinal FDG-PET Metabolic Change Along the Lewy Body Continuum. JAMA Neurol. 2025 Mar 01; 82(3):285-294.
    View PubMed
  14. Ebner BA, Erdahl SA, Lundgreen CS, Vassilaki M, Kremers WK, Knopman DS, Petersen RC, Berry DJ, Lewallen DG, Jannetto PJ, Murray ME, Reichard RR, Maradit Kremers H. Brain tissue metal concentrations and Alzheimer's disease neuropathology in total joint arthroplasty patients versus controls. Acta Neuropathol. 2025 Feb 15; 149 (1):18
    View PubMed
  15. Bornhorst JA, Lundgreen CS, Weigand SD, Figdore DJ, Wiste H, Griswold M, Vemuri P, Graff-Radford J, Knopman DS, Cogswell P, Jack CR, Petersen RC, Algeciras-Schimnich A. Quantitative Assessment of the Effect of Chronic Kidney Disease on Plasma P-Tau217 Concentrations. Neurology. 2025 Feb 11; 104 (3):e210287 Epub 2025 Jan 17
    View PubMed
  16. Gunter J, Senjem M, Nabizadeh F. Local molecular and connectomic contributions of tau-related neurodegeneration. Geroscience. 2025 Feb; 47 (1):227-246 Epub 2024 Sept 30
    View PubMed
  17. Shah J, Krell-Roesch J, Forzani E, Knopman DS, Jack CR, Petersen RC, Che Y, Wu T, Geda YE. Predicting cognitive decline from neuropsychiatric symptoms and Alzheimer's disease biomarkers: A machine learning approach to a population-based data. J Alzheimers Dis. 2025 Feb; 103 (3):833-843 Epub 2025 Jan 10
    View PubMed
  18. Cogswell PM, Wiste HJ, Weigand SD, Therneau TM, Griswold ME, Braunstein JB, West T, Verghese PB, Graff-Radford J, Algeciras-Schimnich A, Lowe VJ, Schwarz CG, Senjem ML, Gunter JL, Knopman DS, Vemuri P, Petersen RC, Jack CR Jr. Plasma Alzheimer's disease biomarker relationships with incident abnormal amyloid PET. Alzheimers Dement. 2025 Feb; 21 (2):e14629
    View PubMed
  19. Ali F, Syrjanen JA, Figdore DJ, Kremers WK, Mielke MM, Jack CR, Knopman DS, Vemuri P, Graff-Radford J, Windham BG, Barnard LR, Petersen RC, Algeciras-Schimnich A. Association of plasma biomarkers of Alzheimer's pathology and neurodegeneration with gait performance in older adults. Commun Med (Lond). 2025 Jan 16; 5 (1):19
    View PubMed
  20. Rabinovici GD, Knopman DS, Arbizu J, Benzinger TLS, Donohoe KJ, Hansson O, Herscovitch P, Kuo PH, Lingler JH, Minoshima S, Murray ME, Price JC, Salloway SP, Weber CJ, Carrillo MC, Johnson KA. Updated Appropriate Use Criteria for Amyloid and Tau PET: A Report from the Alzheimer's Association and Society for Nuclear Medicine and Molecular Imaging Workgroup. J Nucl Med. 2025 Jan 8 Epub 2025 Jan 08
    View PubMed
  21. Rabinovici GD, Knopman DS, Arbizu J, Benzinger TLS, Donohoe KJ, Hansson O, Herscovitch P, Kuo PH, Lingler JH, Minoshima S, Murray ME, Price JC, Salloway SP, Weber CJ, Carrillo MC, Johnson KA. Updated appropriate use criteria for amyloid and tau PET: A report from the Alzheimer's Association and Society for Nuclear Medicine and Molecular Imaging Workgroup. Alzheimers Dement. 2025 Jan; 21 (1):e14338 Epub 2025 Jan 08
    View PubMed
  22. Atri A, Dickerson BC, Clevenger C, Karlawish J, Knopman D, Lin PJ, Norman M, Onyike C, Sano M, Scanland S, Carrillo M. The Alzheimer's Association clinical practice guideline for the diagnostic evaluation, testing, counseling, and disclosure of suspected Alzheimer's disease and related disorders (DETeCD-ADRD): Validated clinical assessment instruments. Alzheimers Dement. 2025 Jan; 21 (1):e14335 Epub 2024 Dec 23
    View PubMed
  23. Dickerson BC, Atri A, Clevenger C, Karlawish J, Knopman D, Lin PJ, Norman M, Onyike C, Sano M, Scanland S, Carrillo M. The Alzheimer's Association clinical practice guideline for the Diagnostic Evaluation, Testing, Counseling, and Disclosure of Suspected Alzheimer's Disease and Related Disorders (DETeCD-ADRD): Executive summary of recommendations for specialty care. Alzheimers Dement. 2025 Jan; 21 (1):e14337 Epub 2024 Dec 23
    View PubMed
  24. Knopman DS. Precision diagnosis of cognitive impairment due to Alzheimer's disease for therapeutic interventions. Alzheimers Dement. 2025 Jan; 21 (1):e14043 Epub 2024 Dec 24
    View PubMed
  25. Atri A, Dickerson BC, Clevenger C, Karlawish J, Knopman D, Lin PJ, Norman M, Onyike C, Sano M, Scanland S, Carrillo M. Alzheimer's Association clinical practice guideline for the Diagnostic Evaluation, Testing, Counseling, and Disclosure of Suspected Alzheimer's Disease and Related Disorders (DETeCD-ADRD): Executive summary of recommendations for primary care. Alzheimers Dement. 2024 Dec 23 [Epub ahead of print]
    View PubMed
  26. Petersen M, Coenen M, DeCarli C, De Luca A, van der Lelij E, Barkhof F, Benke T, Chen CPLH, Dal-Bianco P, Dewenter A, Duering M, Enzinger C, Ewers M, Exalto LG, Fletcher EM, Franzmeier N, Hilal S, Hofer E, Koek HL, Maier AB, Maillard PM, McCreary CR, Papma JM, Pijnenburg YAL, Schmidt R, Smith EE, Steketee RME, van den Berg E, van der Flier WM, Venkatraghavan V, Venketasubramanian N, Vernooij MW, Wolters FJ, Xu X, Horn A, Patil KR, Eickhoff SB, Thomalla G, Biesbroek JM, Biessels GJ, Cheng B. Enhancing cognitive performance prediction by white matter hyperintensity connectivity assessment. Brain. 2024 Dec 3; 147 (12):4265-4279
    View PubMed
  27. Devanand DP, Lee S, Luchsinger JA, Knopman D, Vassilaki M, Motter JN. Comparison of brief olfactory and cognitive assessments to neuroimaging biomarkers in the prediction of cognitive decline and dementia in the MCSA cohort. Alzheimers Dement. 2024 Dec; 20 (12):8346-8358 Epub 2024 Oct 10
    View PubMed
  28. Yu X, Przybelski SA, Reid RI, Gebre RK, Lesnick TG, Vassilaki M, Graff-Radford J, Knopman DS, Petersen RC, Jack CR Jr, Vemuri P. Alzheimer's Imaging Consortium. Alzheimers Dement. 2024 Dec; 20 Suppl 9:e093829. Epub 1900 Jan 01.
  29. Wang T, Pate V, Kim D, Power MC, Garden GA, Palta P, Knopman DS, Jonson-Funk M, Sturmer T, Kucharska-Newton AM. Drug Development. Alzheimers Dement. 2024 Dec; 20 Suppl 6:e089988
    View PubMed
  30. Eswaran S, Gottesman RF, Knopman DS, Koton S, Kucharska-Newton AM, Liu AC, Liu C, Lutsey PL, Mosley TH, Palta P, Sharrett AR, Sullivan KJ, Walker KA, Groechel R. Alzheimer's Imaging Consortium. Alzheimers Dement. 2024 Dec; 20 Suppl 9:e093711
    View PubMed
  31. Pike JR, Lu Y, Chen J, Walker KA, Sullivan KJ, Griswold ME, Thyagarajan B, Mielke MM, Lutsey PL, Wong DF, Knopman DS, Sharrett AR, Coresh J, Mosley TH, Gottesman RF, Palta P. Biomarkers. Alzheimers Dement. 2024 Dec; 20 Suppl 2:e091307
    View PubMed
  32. Figdore D, Bornhorst JA, Graff-Radford J, Vemuri P, Knopman DS, Jack CR Jr, Petersen RC, Algeciras-Schimnich A. Biomarkers. Alzheimers Dement. 2024 Dec; 20 Suppl 2:e087493
    View PubMed
  33. Smith JR, Pike JR, Selvin E, Lutsey PL, Palta P, Knopman DS, Windham BG, Coresh J, Sharrett R, Gross AL, Deal JA. Public Health. Alzheimers Dement. 2024 Dec; 20 Suppl 7:e084043
    View PubMed
  34. Eswaran S, Gottesman RF, Knopman DS, Koton S, Kucharska-Newton AM, Liu AC, Liu C, Lutsey PL, Mosley TH, Palta P, Sharrett AR, Sullivan KJ, Walker KA, Groechel R. Public Health. Alzheimers Dement. 2024 Dec; 20 Suppl 7:e087094
    View PubMed
  35. Devanand D, Lee S, Knopman DS, Vassilaki M, Luchsinger JA, Motter JN. Biomarkers. Alzheimers Dement. 2024 Dec; 20 Suppl 2:e084722
    View PubMed
  36. Corriveau-Lecavalier N, Botha H, Graff-Radford J, Switzer A, Przybelski SA, Wiste HJ, Murray ME, Reichard RR, Dickson DW, Nguyen AT, Ramanan VK, McCarter SJ, Boeve B, Machulda MM, Fields JA, Stricker NH, Nelson PT, Grothe MJ, Knopman DS, Lowe VJ, Petersen RC, Jack CR Jr, Jones DT. Clinical Manifestations. Alzheimers Dement. 2024 Dec; 20 Suppl 3:e084087
    View PubMed
  37. Stricker NH, Frank RD, Boots EA, Fan WZ, Christianson TJ, Kremers WK, Stricker JL, Machulda MM, Lucas JA, Hassenstab JJ, Graff-Radford J, Vemuri P, Jack CR Jr, Knopman DS, Petersen RC. Clinical Manifestations. Alzheimers Dement. 2024 Dec; 20 Suppl 3:e085612
    View PubMed
  38. Gebre RK, Moscoso A, Raghavan S, Wiste HJ, Heeman F, Costoya-Sanchez A, Schwarz CG, Spychalla AJ, Lowe VJ, Graff-Radford J, Knopman DS, Petersen RC, Scholl M, Murray ME, Jack CR Jr, Vemuri P. Basic Science and Pathogenesis. Alzheimers Dement. 2024 Dec; 20 Suppl 1:e091770
    View PubMed
  39. Flagan TM, Chu SA, Hakkinen S, Zhang L, McFall D, Heller C, Rohrer JD, Brown JA, Lee AJ, Fernhoff K, Pasquini L, Mandelli ML, Tempini MLG, Yokoyama JS, Sturm V, Appleby B, Dickerson BC, Domoto-Reilly K, Foroud TM, Geschwind DH, Ghoshal N, Graff-Radford NR, Grossman M, Hsiung GR, Huang EJ, Huey ED, Kantarci K, Karydas AM, Kaufer D, Knopman DS, Litvan I, MacKenzie IR, Mendez MF, Onyike CU, Petrucelli L, Ramos EM, Roberson ED, Rojas JC, Tartaglia MC, Toga AW, Weintraub S, Forsberg LK, Heuer HW, Boeve BF, Boxer AL, Rosen HJ, Miller BL, Moreno F, Seeley WW, Lee SE, ARTFL/LEFFTDS Consortia. Basic Science and Pathogenesis. Alzheimers Dement. 2024 Dec; 20 Suppl 1:e087301
    View PubMed
  40. Stricker NH, Frank RD, Boots EA, Fan WZ, Christianson TJ, Kremers WK, Stricker JL, Machulda MM, Lucas JA, Hassenstab JJ, Graff-Radford J, Vemuri P, Jack CR Jr, Knopman DS, Petersen RC. Technology and Dementia Preconference. Alzheimers Dement. 2024 Dec; 20 Suppl 10:e094197
    View PubMed
  41. Pillai JJ, Reid RI, Weigand SD, Cogswell PM, Vemuri P, Machulda MM, Knopman DS, Graff-Radford J, Petersen RC, Jack CR Jr. Alzheimer's Imaging Consortium. Alzheimers Dement. 2024 Dec; 20 Suppl 9:e093997
    View PubMed
  42. Hu M, Moloney CM, Przybelski SA, Algeciras-Schimnich A, Fought AJ, Rothberg DM, Nguyen AT, Reichard RR, Dickson DW, Knopman DS, Jack CR Jr, Petersen RC, Mielke MM, Graff-Radford J, Murray ME, Vemuri P. Alzheimer's Imaging Consortium. Alzheimers Dement. 2024 Dec; 20 Suppl 9:e093893
    View PubMed
  43. Schwarz CG, Prakaashana CM, Kremers WK, Gunter JL, Senjem ML, Vemuri P, Kantarci K, Graff-Radford J, Knopman DS, Petersen RC, Jack CR Jr. Alzheimer's Imaging Consortium. Alzheimers Dement. 2024 Dec; 20 Suppl 9:e093968
    View PubMed
  44. Tian J, Raghavan S, Cogswell PM, Reid RI, Przybelski SA, Schwarz CG, Graff-Radford J, Lowe VJ, Kantarci K, Knopman DS, Petersen RC, Jack CR Jr, Vemuri P. Alzheimer's Imaging Consortium. Alzheimers Dement. 2024 Dec; 20 Suppl 9:e093924
    View PubMed
  45. Raghavan S, Reid RI, Przybelski SA, Kamykowski MG, Lesnick TG, Graff-Radford J, Lowe VJ, Knopman DS, Jack CR Jr, Petersen RC, Vemuri P. Alzheimer's Imaging Consortium. Alzheimers Dement. 2024 Dec; 20 Suppl 9:e093870
    View PubMed
  46. Prakaashana CM, Savvides M, Gunter JL, Senjem ML, Vemuri P, Kantarci K, Graff-Radford J, Knopman DS, Petersen RC, Jack CR Jr, Schwarz CG. Alzheimer's Imaging Consortium. Alzheimers Dement. 2024 Dec; 20 Suppl 9:e093977
    View PubMed
  47. Reid RI, Przybelski SA, Lesnick TG, Fought AJ, Raghavan S, Kamykowski MG, Graff-Radford J, Knopman DS, Petersen RC, Jack CR Jr, Vemuri P. Alzheimer's Imaging Consortium. Alzheimers Dement. 2024 Dec; 20 Suppl 9:e093860
    View PubMed
  48. Schwarz CG, Kremers WK, Prakaashana CM, Przybelski SA, Christenson LR, Wiliams JM, Gunter JL, Senjem ML, Arani A, Reid RI, Machulda MM, Fields JA, Lowe VJ, Kantarci K, Graff-Radford J, Vemuri P, Petersen RC, Knopman DS, Jack CR Jr. Alzheimer's Imaging Consortium. Alzheimers Dement. 2024 Dec; 20 Suppl 9:e093966
    View PubMed
  49. Ramanan VK, Graff-Radford J, Bornhorst JA, Johnson DR, Cogswell PM, Burkett BJ, Lowe VJ, Stricker NH, Botha H, Jones DT, McCarter SJ, Neth BJ, Jack CR Jr, Knopman DS, Petersen RC, Algeciras-Schimnich A. Developing Topics. Alzheimers Dement. 2024 Dec; 20 Suppl 8:e095777
    View PubMed
  50. Vassilaki M, Aakre JA, Castillo AM, Lesnick TG, Kremers WK, Algeciras-Schimnich A, Graff-Radford J, Knopman DS, Mosley TH, Windham BG, Griswold ME, Lowe VJ, Jack CR Jr, Petersen RC, Vemuri P. Developing Topics. Alzheimers Dement. 2024 Dec; 20 Suppl 8:e095372
    View PubMed
  51. Hughes MA, Frank RD, Fan WZ, Christianson TJ, Kremers WK, Stricker JL, Boots EA, Machulda MM, Fields JA, Hassenstab JJ, Aduen P, Lucas JA, Graff-Radford J, Vemuri P, Jack CR Jr, Knopman DS, Petersen RC, Stricker NH. Developing Topics. Alzheimers Dement. 2024 Dec; 20 Suppl 8:e095558
    View PubMed
  52. Schwarz CG, Prakaashana CM, Kremers WK, Gunter JL, Senjem ML, Vemuri P, Kantarci K, Graff-Radford J, Knopman DS, Petersen RC, Jack CR Jr, Alzheimer's Disease Neuroimaging Initiative. Biomarkers. Alzheimers Dement. 2024 Dec; 20 Suppl 2:e091376
    View PubMed
  53. Schwarz CG, Kremers WK, Prakaashana CM, Przybelski SA, Christenson LR, Wiliams JM, Gunter JL, Senjem ML, Arani A, Reid RI, Machulda MM, Fields JA, Lowe VJ, Kantarci K, Graff-Radford J, Vemuri P, Petersen RC, Knopman DS, Jack CR Jr. Biomarkers. Alzheimers Dement. 2024 Dec; 20 Suppl 2:e091346
    View PubMed
  54. Tian J, Raghavan S, Cogswell PM, Reid RI, Przybelski SA, Schwarz CG, Graff-Radford J, Lowe VJ, Kantarci K, Knopman DS, Petersen RC, Jack CR Jr, Vemuri P. Biomarkers. Alzheimers Dement. 2024 Dec; 20 Suppl 2:e090927
    View PubMed
  55. Lowe VJ, Mester CT, Lundt ES, Lee J, Ghatamaneni S, Algeciras-Schimnich A, Campbell MR, Graff-Radford J, Nguyen AT, Min HK, Murray ME, Senjem ML, Schwarz CG, Kantarci K, Boeve BF, Vemuri P, Jones DT, Knopman DS, Jack CR Jr, Petersen RC, Mielke MM. Biomarkers. Alzheimers Dement. 2024 Dec; 20 Suppl 2:e092471
    View PubMed
  56. Windham BG, Blackshear CT, Ali F, Knopman DS, Walker KA, Pike JR, Lu Y, Mosley TH, Palta P, Griswold ME. Biomarkers. Alzheimers Dement. 2024 Dec; 20 Suppl 2:e086174
    View PubMed
  57. Yu X, Przybelski SA, Reid RI, Gebre RK, Lesnick TG, Vassilaki M, Graff-Radford J, Knopman DS, Petersen RC, Jack CR Jr, Vemuri P. Public Health. Alzheimers Dement. 2024 Dec; 20 Suppl 7:e089382
    View PubMed
  58. Sheets KM, Knopman DS, Petersen RC, Vemuri P, Jones C, Murray A. Public Health. Alzheimers Dement. 2024 Dec; 20 Suppl 7:e087005
    View PubMed
  59. Prakaashana CM, Savvides M, Gunter JL, Senjem ML, Vemuri P, Kantarci K, Graff-Radford J, Knopman DS, Petersen RC, Jack CR Jr, Schwarz CG. Biomarkers. Alzheimers Dement. 2024 Dec; 20 Suppl 2:e091462
    View PubMed
  60. Raghavan S, Hofrenning EI, Fought AJ, Algeciras-Schimnich A, Knopman DS, Jack CR Jr, Petersen RC, Lowe VJ, Graff-Radford J, Vemuri P. Biomarkers. Alzheimers Dement. 2024 Dec; 20 Suppl 2:e090142
    View PubMed
  61. Pillai JJ, Reid RI, Weigand SD, Cogswell PM, Vemuri P, Machulda MM, Knopman DS, Graff-Radford J, Petersen RC, Jack CR Jr. Biomarkers. Alzheimers Dement. 2024 Dec; 20 Suppl 2:e091698
    View PubMed
  62. Mak E, Reid RI, Przybelski SA, Lesnick TG, Schwarz CG, Senjem ML, Raghavan S, Vemuri P, Jack CR Jr, Min HK, Jain MK, Miyagawa T, Forsberg LK, Fields JA, Savica R, Graff-Radford J, Jones DT, Botha H, St Louis EK, Knopman DS, Ramanan VK, Dickson DW, Graff-Radford NR, Ferman TJ, Petersen RC, Lowe VJ, Boeve B, O'Brien JT, Kantarci K. Biomarkers. Alzheimers Dement. 2024 Dec; 20 Suppl 2:e089309
    View PubMed
  63. Cogswell PM, Lundt ES, Therneau TM, Griswold ME, Graff-Radford J, Algeciras-Schimnich A, Lowe VJ, Schwarz CG, Senjem ML, Gunter JL, Knopman DS, Vemuri P, Petersen RC, Jack CR Jr. Biomarkers. Alzheimers Dement. 2024 Dec; 20 Suppl 2:e090361
    View PubMed
  64. Reid RI, Przybelski SA, Lesnick TG, Fought AJ, Raghavan S, Kamykowski MG, Graff-Radford J, Knopman DS, Petersen RC, Jack CR Jr, Vemuri P. Biomarkers. Alzheimers Dement. 2024 Dec; 20 Suppl 2:e089998
    View PubMed
  65. Raghavan S, Reid RI, Przybelski SA, Kamykowski MG, Lesnick TG, Graff-Radford J, Lowe VJ, Knopman DS, Jack CR Jr, Petersen RC, Vemuri P. Biomarkers. Alzheimers Dement. 2024 Dec; 20 Suppl 2:e090097
    View PubMed
  66. Bermudez C, Syrjanen JA, Attia ZI, Friedman PA, Lopez-Jimenez F, Hu M, Petersen RC, Knopman DS, Ramanan VK, Jack CR Jr, Nguyen AT, Reichard RR, Kouri N, Moloney CM, Algeciras-Schimnich A, Murray ME, Mielke MM, Vemuri P, Noseworthy PA, Graff-Radford J. Biomarkers. Alzheimers Dement. 2024 Dec; 20 Suppl 2:e088037
    View PubMed
  67. Hu M, Moloney CM, Przybelski SA, Algeciras-Schimnich A, Fought AJ, Rothberg DM, Nguyen AT, Reichard RR, Dickson DW, Knopman DS, Jack CR Jr, Petersen RC, Mielke MM, Graff-Radford J, Murray ME, Vemuri P. Biomarkers. Alzheimers Dement. 2024 Dec; 20 Suppl 2:e090563
    View PubMed
  68. Satpathi S, Reid RI, Przybelski SA, Raghavan S, Gunter JL, Knopman DS, Petersen RC, Cogswell PM, Jack CR Jr, Radford JG, Vemuri P. Biomarkers. Alzheimers Dement. 2024 Dec; 20 Suppl 2:e087185
    View PubMed
  69. Motter JN, Lee S, Knopman DS, Vassilaki M, Devanand D. Clinical Manifestations. Alzheimers Dement. 2024 Dec; 20 Suppl 3:e088601
    View PubMed
  70. Pike JR, Huang AR, Deal JA, Reed NS, Burgard S, Chisolm T, Couper D, Glynn NW, Gmelin T, Goman AM, Gravens-Mueller L, Hayden KM, Mitchell C, Pankow J, Sanchez VA, Schrack JA, Albert MS, Jack CR Jr, Knopman DS, Coresh J, Lin FR, ACHIEVE Collaborative Research Group. Clinical Manifestations. Alzheimers Dement. 2024 Dec; 20 Suppl 3:e086740
    View PubMed
  71. Essa H, Ali HM, Min PH, Ali DN, Lowe V, Petersen RC, Knopman DS, Lundt ES, Mester CT, Bormann NL, Choi DS. Impact of alcohol use disorder on cognition in correlation with aging: a community-based retrospective cohort study. Alcohol Alcohol. 2024 Nov 18; 60 (1)
    View PubMed
  72. Feldman HH, Cummings JL, Boxer AL, Staffaroni AM, Knopman DS, Sukoff Rizzo SJ, Territo PR, Arnold SE, Ballard C, Beher D, Boeve BF, Dacks PA, Diaz K, Ewen C, Fiske B, Gonzalez MI, Harris GA, Hoffman BJ, Martinez TN, McDade E, Nisenbaum LK, Palma JA, Quintana M, Rabinovici GD, Rohrer JD, Rosen HJ, Troyer MD, Kim DY, Tanzi RE, Zetterberg H, Ziogas NK, May PC, Rommel A. A framework for translating tauopathy therapeutics: Drug discovery to clinical trials. Alzheimers Dement. 2024 Nov; 20 (11):8129-8152 Epub 2024 Sept 24
    View PubMed
  73. Lowe VJ, Mester CT, Lundt ES, Lee J, Ghatamaneni S, Algeciras-Schimnich A, Campbell MR, Graff-Radford J, Nguyen A, Min HK, Senjem ML, Machulda MM, Schwarz CG, Dickson DW, Murray ME, Kandimalla KK, Kantarci K, Boeve B, Vemuri P, Jones DT, Knopman D, Jack CR Jr, Petersen RC, Mielke MM. Amyloid PET detects the deposition of brain Abeta earlier than CSF fluid biomarkers. Alzheimers Dement. 2024 Nov; 20 (11):8097-8112 Epub 2024 Oct 11
    View PubMed
  74. Krell-Roesch J, Syrjanen JA, Moeller T, Krafft J, Barisch-Fritz B, Kremers WK, Ali F, Knopman DS, Petersen RC, Stein T, Woll A, Vassilaki M, Geda YE. Self-reported physical activity and gait in older adults without dementia: A longitudinal study. Health Sci Rep. 2024 Nov; 7 (11):e70108 Epub 2024 Nov 06
    View PubMed
  75. Vandebergh M, Ramos EM, Corriveau-Lecavalier N, Ramanan VK, Kornak J, Mester C, Kolander T, Brushaber DE, Staffaroni AM, Geschwind DH, Wolf AA, Kantarci K, Gendron T, Petrucelli L, Van den Broeck M, Wynants S, Baker M, Borrego-Ecija S, Appleby B, Barmada S, Bozoki AC, Clark D, Darby RR, Dickerson BC, Domoto-Reilly K, Fields JA, Galasko D, Ghoshal N, Graff-Radford NR, Grant IM, Honig LS, Hsiung GR, Huey ED, Irwin DJ, Knopman DS, Kwan JY, Leger GC, Litvan I, Masdeu JC, Mendez MF, Onyike CU, Pascual B, Pressman PS, Ritter A, Roberson ED, Snyder A, Sullivan AC, Tartaglia MC, Wint D, Heuer HW, Forsberg LK, Boxer AL, Rosen HJ, Boeve BF, Rademakers R, ALLFTD Consortium. Gene-Specific Effects on Brain Volume and Cognition of TMEM106B in Frontotemporal Lobar Degeneration. Neurology. 2024 Oct 22; 103 (8):e209832 Epub 2024 Sept 25
    View PubMed
  76. Lu Y, Pike JR, Chen J, Walker KA, Sullivan KJ, Thyagarajan B, Mielke MM, Lutsey PL, Knopman D, Gottesman RF, Sharrett AR, Coresh J, Mosley TH, Palta P. Changes in Alzheimer Disease Blood Biomarkers and Associations With Incident All-Cause Dementia. JAMA 2024 Oct 15; 332 (15):1258-1269
    View PubMed
  77. VandeBunte AM, Lee H, Paolillo EW, Hsiung GR, Staffaroni AM, Saloner R, Tartaglia C, Yaffe K, Knopman DS, Ramos EM, Rascovsky K, Bozoki AC, Wong B, Domoto-Reilly K, Snyder A, Pressman P, Mendez MF, Litvan I, Fields JA, Galasko DR, Darby R, Masdeu JC, Pasqual MB, Honig LS, Ghoshal N, Appleby BS, Mackenzie IR, Heuer HW, Kramer JH, Boxer AL, Forsberg LK, Boeve B, Rosen HJ, Casaletto KB, ALLFTD Consortium. Better cardiovascular health is associated with slowed clinical progression in autosomal dominant frontotemporal lobar degeneration variant carriers. Alzheimers Dement. 2024 Oct; 20 (10):6820-6833 Epub 2024 Sept 06
    View PubMed
  78. Eswaran S, Knopman DS, Koton S, Kucharska-Newton AM, Liu AC, Liu C, Lutsey PL, Mosley TH Jr, Palta P, Sharrett AR, Sullivan KJ, Walker KA, Gottesman RF, Groechel RC. Psychosocial Health and the Association Between Cerebral Small Vessel Disease Markers With Dementia: The ARIC Study. Stroke. 2024 Oct; 55 (10):2449-2458 Epub 2024 Aug 28
    View PubMed
  79. Gunter J, Senjem M, Kim KY, Kim E, Lee JY. Impact of amyloid and cardiometabolic risk factors on prognostic capacity of plasma neurofilament light chain for neurodegeneration. Alzheimers Res Ther. 2024 Sep 12; 16 (1):202 Epub 2024 Sept 12
    View PubMed
  80. Zhao D, Guallar E, Qiao Y, Knopman DS, Palatino M, Gottesman RF, Mosley TH Jr, Wasserman BA. Intracranial Atherosclerotic Disease and Incident Dementia: The ARIC Study (Atherosclerosis Risk in Communities). Circulation. 2024 Sep 10; 150 (11):838-847 Epub 2024 Aug 01
    View PubMed
  81. Gebre RK, Rial AM, Raghavan S, Wiste HJ, Heeman F, Costoya-Sanchez A, Schwarz CG, Spychalla AJ, Lowe VJ, Graff-Radford J, Knopman DS, Petersen RC, Scholl M, Murray ME, Jack CR Jr, Vemuri P, Alzheimer's Disease Neuroimaging Initiative. Advancing Tau PET Quantification in Alzheimer Disease with Machine Learning: Introducing THETA, a Novel Tau Summary Measure. J Nucl Med. 2024 Sep 3; 65 (9):1473-1480 Epub 2024 Sept 03
    View PubMed
  82. Jiang K, Albert MS, Coresh J, Couper DJ, Gottesman RF, Hayden KM, Jack CR Jr, Knopman DS, Mosley TH, Pankow JS, Pike JR, Reed NS, Sanchez VA, Sharrett AR, Lin FR, Deal JA, ACHIEVE Collaborative Study. Cross-Sectional Associations of Peripheral Hearing, Brain Imaging, and Cognitive Performance With Speech-in-Noise Performance: The Aging and Cognitive Health Evaluation in Elders Brain Magnetic Resonance Imaging Ancillary Study. Am J Audiol. 2024 Sep 3; 33 (3):683-694 Epub 2024 May 15
    View PubMed
  83. Figdore DJ, Griswold M, Bornhorst JA, Graff-Radford J, Ramanan VK, Vemuri P, Lowe VJ, Knopman DS, Jack CR Jr, Petersen RC, Algeciras-Schimnich A. Optimizing cutpoints for clinical interpretation of brain amyloid status using plasma p-tau217 immunoassays. Alzheimers Dement. 2024 Sep; 20 (9):6506-6516 Epub 2024 July 19
    View PubMed
  84. Lila E, Zhang W, Rane Levendovszky S. Interpretable discriminant analysis for functional data supported on random nonlinear domains with an application to Alzheimer's disease. J R Stat Soc Series B Stat Methodol. 2024 Sep; 86 (4):1013-1044 Epub 2024 Mar 22
    View PubMed
  85. Shir D, Corriveau-Lecavalier N, Bermudez Noguera C, Barnard L, Pham NTT, Botha H, Duffy JR, Clark HM, Utianski RL, Knopman DS, Petersen RC, Boeve BF, Murray ME, Nguyen AT, Reichard RR, Dickson DW, Day GS, Kremers WK, Graff-Radford NR, Jones DT, Machulda MM, Fields JA, Whitwell JL, Josephs KA, Graff-Radford J. Clinicoradiological and neuropathological evaluation of primary progressive aphasia. J Neurol Neurosurg Psychiatry. 2024 Aug 16; 95 (9):812-821
    View PubMed
  86. Quattrone A, Franzmeier N, Huppertz HJ, Klietz M, Roemer SN, Boxer AL, Levin J, Hoglinger GU. Magnetic Resonance Imaging Measures to Track Atrophy Progression in Progressive Supranuclear Palsy in Clinical Trials. Mov Disord. 2024 Aug; 39 (8):1329-1342 Epub 2024 June 02
    View PubMed
  87. Li W, Petersen RC, Algeciras-Schimnich A, Cogswell PM, Bornhorst JA, Kremers WK, Boeve BF, Jones DT, Botha H, Ramanan VK, Knopman DS, Savica R, Josephs KA, Cliatt-Brown C, Andersen E, Day GS, Graff-Radford NR, Ertekin-Taner N, Lachner C, Wicklund M, van Harten A, Woodruff BK, Caselli RJ, Graff-Radford J. Alzheimer Disease Cerebrospinal Fluid Biomarkers in a Tertiary Neurology Practice. Mayo Clin Proc. 2024 Aug; 99 (8):1284-1296 Epub 2024 June 25
    View PubMed
  88. Altmann A, Aksman LM, Oxtoby NP, Young AL, Alexander DC, Barkhof F, Shoai M, Hardy J, Schott JM. Towards cascading genetic risk in Alzheimer's disease. Brain. 2024 Aug 1; 147 (8):2680-2690
    View PubMed
  89. Josephs KA, Tosakulwong N, Weigand SD, Graff-Radford J, Schwarz CG, Senjem ML, Machulda MM, Kantarci K, Knopman DS, Nguyen A, Reichard RR, Dickson DW, Petersen RC, Lowe VJ, Jack CR Jr, Whitwell JL. Flortaucipir PET uncovers relationships between tau and amyloid-beta in primary age-related tauopathy and Alzheimer's disease. Sci Transl Med. 2024 Jul 24; 16 (757):eado8076 Epub 2024 July 24
    View PubMed
  90. Manzoni C, Kia DA, Ferrari R, Leonenko G, Costa B, Saba V, Jabbari E, Tan MM, Albani D, Alvarez V, Alvarez I, Andreassen OA, Angiolillo A, Arighi A, Baker M, Benussi L, Bessi V, Binetti G, Blackburn DJ, Boada M, Boeve BF, Borrego-Ecija S, Borroni B, Brathen G, Brooks WS, Bruni AC, Caroppo P, Bandres-Ciga S, Clarimon J, Colao R, Cruchaga C, Danek A, de Boer SC, de Rojas I, di Costanzo A, Dickson DW, Diehl-Schmid J, Dobson-Stone C, Dols-Icardo O, Donizetti A, Dopper E, Durante E, Ferrari C, Forloni G, Frangipane F, Fratiglioni L, Kramberger MG, Galimberti D, Gallucci M, Garcia-Gonzalez P, Ghidoni R, Giaccone G, Graff C, Graff-Radford NR, Grafman J, Halliday GM, Hernandez DG, Hjermind LE, Hodges JR, Holloway G, Huey ED, Illan-Gala I, Josephs KA, Knopman DS, Kristiansen M, Kwok JB, Leber I, Leonard HL, Libri I, Lleo A, Mackenzie IR, Madhan GK, Maletta R, Marquie M, Maver A, Menendez-Gonzalez M, Milan G, Miller BL, Morris CM, Morris HR, Nacmias B, Newton J, Nielsen JE, Nilsson C, Novelli V, Padovani A, Pal S, Pasquier F, Pastor P, Perneczky R, Peterlin B, Petersen RC, Piguet O, Pijnenburg YA, Puca AA, Rademakers R, Rainero I, Reus LM, Richardson AM, Riemenschneider M, Rogaeva E, Rogelj B, Rollinson S, Rosen H, Rossi G, Rowe JB, Rubino E, Ruiz A, Salvi E, Sanchez-Valle R, Sando SB, Santillo AF, Saxon JA, Schlachetzki JC, Scholz SW, Seelaar H, Seeley WW, Serpente M, Sorbi S, Sordon S, St George-Hyslop P, Thompson JC, Van Broeckhoven C, Van Deerlin VM, Van der Lee SJ, Van Swieten J, Tagliavini F, van der Zee J, Veronesi A, Vitale E, Waldo ML, Yokoyama JS, Nalls MA, Momeni P, Singleton AB, Hardy J, Escott-Price V. Genome-wide analyses reveal a potential role for the MAPT, MOBP, and APOE loci in sporadic frontotemporal dementia. Am J Hum Genet. 2024 Jul 11; 111 (7):1316-1329 Epub 2024 June 17
    View PubMed
  91. Pradeep A, Raghavan S, Przybelski SA, Preboske GM, Schwarz CG, Lowe VJ, Knopman DS, Petersen RC, Jack CR Jr, Graff-Radford J, Cogswell PM, Vemuri P. Can white matter hyperintensities based Fazekas visual assessment scales inform about Alzheimer's disease pathology in the population? Alzheimers Res Ther. 2024 Jul 10; 16(1):157.
    View PubMed
  92. Robinson CG, Goodrich AW, Weigand SD, Pham NTT, Carlos AF, Buciuc M, Murray ME, Nguyen AT, Reichard RR, Knopman DS, Petersen RC, Dickson DW, Utianski RL, Whitwell JL, Josephs KA, Machulda MM. Determinants of confrontation naming deficits on the Boston Naming Test associated with transactive response DNA-binding protein 43 pathology. J Int Neuropsychol Soc. 2024 Jul; 30 (6):575-583 Epub 2024 Mar 25
    View PubMed
  93. Yu X, Przybelski SA, Reid RI, Lesnick TG, Raghavan S, Graff-Radford J, Lowe VJ, Kantarci K, Knopman DS, Petersen RC, Jack CR Jr, Vemuri P. NODDI in gray matter is a sensitive marker of aging and early AD changes. Alzheimers Dement (Amst). 2024 Jul-Sep; 16 (3):e12627 Epub 2024 July 29
    View PubMed
  94. Lecy EE, Min HK, Apgar CJ, Maltais DD, Lundt ES, Albertson SM, Senjem ML, Schwarz CG, Botha H, Graff-Radford J, Jones DT, Vemuri P, Kantarci K, Knopman DS, Petersen RC, Jack CR Jr, Lee J, Lowe VJ. Patterns of Early Neocortical Amyloid-beta Accumulation: A PET Population-Based Study. J Nucl Med. 2024 Jul 1; 65 (7):1122-1128 Epub 2024 July 01
    View PubMed
  95. Knopman DS, Pike JR, Gottesman RF, Sharrett AR, Windham BG, Mosley TH Jr, Sullivan K, Albert MS, Walker KA, Yasar S, Burgard S, Li D, Gross AL. Patterns of cognitive domain abnormalities enhance discrimination of dementia risk prediction: The ARIC study. Alzheimers Dement. 2024 Jul; 20 (7):4559-4571 Epub 2024 June 14
    View PubMed
  96. Kouri N, Frankenhauser I, Peng Z, Labuzan SA, Boon BDC, Moloney CM, Pottier C, Wickland DP, Caetano-Anolles K, Corriveau-Lecavalier N, Tranovich JF, Wood AC, Hinkle KM, Lincoln SJ, Spychalla AJ, Senjem ML, Przybelski SA, Engelberg-Cook E, Schwarz CG, Kwan RS, Lesser ER, Crook JE, Carter RE, Ross OA, Lachner C, Ertekin-Taner N, Ferman TJ, Fields JA, Machulda MM, Ramanan VK, Nguyen AT, Reichard RR, Jones DT, Graff-Radford J, Boeve BF, Knopman DS, Petersen RC, Jack CR Jr, Kantarci K, Day GS, Duara R, Graff-Radford NR, Dickson DW, Lowe VJ, Vemuri P, Murray ME. Clinicopathologic Heterogeneity and Glial Activation Patterns in Alzheimer Disease. JAMA Neurol. 2024 Jun 1; 81 (6):619-629
    View PubMed
  97. Switzer AR, Charidimou A, McCarter S, Vemuri P, Nguyen AT, Przybelski SA, Lesnick TG, Rabinstein AA, Brown RD, Knopman DS, Petersen RC, Jack CR Jr, Reichard RR, Graff-Radford J. Boston Criteria v2.0 for Cerebral Amyloid Angiopathy Without Hemorrhage: An MRI-Neuropathologic Validation Study. Neurology. 2024 May 28; 102 (10):e209386 Epub 2024 May 06
    View PubMed
  98. Karstens AJ, Christianson TJ, Lundt ES, Machulda MM, Mielke MM, Fields JA, Kremers WK, Graff-Radford J, Vemuri P, Jack CR Jr, Knopman DS, Petersen RC, Stricker NH. Mayo normative studies: regression-based normative data for ages 30-91 years with a focus on the Boston Naming Test, Trail Making Test and Category Fluency. J Int Neuropsychol Soc. 2024 May; 30 (4):389-401 Epub 2023 Nov 28
    View PubMed
  99. Udine E, DeJesus-Hernandez M, Tian S, das Neves SP, Crook R, Finch NA, Baker MC, Pottier C, Graff-Radford NR, Boeve BF, Petersen RC, Knopman DS, Josephs KA, Oskarsson B, Da Mesquita S, Petrucelli L, Gendron TF, Dickson DW, Rademakers R, van Blitterswijk M. Abundant transcriptomic alterations in the human cerebellum of patients with a C9orf72 repeat expansion. Acta Neuropathol. 2024 Apr 19; 147 (1):73
    View PubMed
  100. Nguyen HV, Mital S, Knopman DS, Alexander GC. Cost-Effectiveness of Lecanemab for Individuals With Early-Stage Alzheimer Disease. Neurology. 2024 Apr 9; 102 (7):e209218 Epub 2024 Mar 14
    View PubMed
  101. Corriveau-Lecavalier N, Barnard LR, Botha H, Graff-Radford J, Ramanan VK, Lee J, Dicks E, Rademakers R, Boeve BF, Machulda MM, Fields JA, Dickson DW, Graff-Radford N, Knopman DS, Lowe VJ, Petersen RC, Jack CR Jr, Jones DT. Uncovering the distinct macro-scale anatomy of dysexecutive and behavioural degenerative diseases. Brain. 2024 Apr 4; 147 (4):1483-1496
    View PubMed
  102. Mak E, Reid RI, Przybelski SA, Lesnick TG, Schwarz CG, Senjem ML, Raghavan S, Vemuri P, Jack CR Jr, Min HK, Jain MK, Miyagawa T, Forsberg LK, Fields JA, Savica R, Graff-Radford J, Jones DT, Botha H, St Louis EK, Knopman DS, Ramanan VK, Dickson DW, Graff-Radford NR, Ferman TJ, Petersen RC, Lowe VJ, Boeve BF, O'Brien JT, Kantarci K. Influences of amyloid-ß and tau on white matter neurite alterations in dementia with Lewy bodies. NPJ Parkinsons Dis. 2024 Apr 03; 10(1):76.
    View PubMed
  103. Staffaroni AM, Clark AL, Taylor JC, Heuer HW, Sanderson-Cimino M, Wise AB, Dhanam S, Cobigo Y, Wolf A, Manoochehri M, Forsberg L, Mester C, Rankin KP, Appleby BS, Bayram E, Bozoki A, Clark D, Darby RR, Domoto-Reilly K, Fields JA, Galasko D, Geschwind D, Ghoshal N, Graff-Radford N, Grossman M, Hsiung GY, Huey ED, Jones DT, Lapid MI, Litvan I, Masdeu JC, Massimo L, Mendez MF, Miyagawa T, Pascual B, Pressman P, Ramanan VK, Ramos EM, Rascovsky K, Roberson ED, Tartaglia MC, Wong B, Miller BL, Kornak J, Kremers W, Hassenstab J, Kramer JH, Boeve BF, Rosen HJ, Boxer AL, ALLFTD Consortium. Reliability and Validity of Smartphone Cognitive Testing for Frontotemporal Lobar Degeneration. JAMA Netw Open. 2024 Apr 1; 7 (4):e244266 Epub 2024 Apr 01
    View PubMed
  104. Groechel RC, Liu AC, Liu C, Knopman DS, Koton S, Kucharska-Newton AM, Lutsey PL, Mosley TH Jr, Palta P, Sharrett AR, Walker KA, Wong DF, Gottesman RF. Social relationships, amyloid burden, and dementia: The ARIC-PET study. Alzheimers Dement (Amst). 2024 Apr-Jun; 16 (2):e12560 Epub 2024 Apr 02
    View PubMed
  105. Diaz-Galvan P, Przybelski SA, Algeciras-Schimnich A, Figdore DJ, Lesnick TG, Schwarz CG, Senjem ML, Gunter JL, Jack CR Jr, Min PH, Jain MK, Miyagawa T, Forsberg LK, Fields JA, Savica R, Graff-Radford J, Ramanan VK, Jones DT, Botha H, St Louis EK, Knopman DS, Graff-Radford NR, Ferman TJ, Petersen RC, Lowe VJ, Boeve BF, Kantarci K. Plasma biomarkers of Alzheimer's disease in the continuum of dementia with Lewy bodies. Alzheimers Dement. 2024 Apr; 20(4):2485-2496. Epub 2024 Feb 08.
    View PubMed
  106. Boots EA, Frank RD, Fan WZ, Christianson TJ, Kremers WK, Stricker JL, Machulda MM, Fields JA, Hassenstab J, Graff-Radford J, Vemuri P, Jack CR, Knopman DS, Petersen RC, Stricker NH. Continuous Associations Between Remote Self-Administered Cognitive Measures and Imaging Biomarkers of Alzheimer's Disease medRxiv. 2024.
  107. Lee J, Burkett BJ, Min HK, Senjem ML, Dicks E, Corriveau-Lecavalier N, Mester CT, Wiste HJ, Lundt ES, Murray ME, Nguyen AT, Reichard RR, Botha H, Graff-Radford J, Barnard LR, Gunter JL, Schwarz CG, Kantarci K, Knopman DS, Boeve BF, Lowe VJ, Petersen RC, Jack CR Jr, Jones DT. Synthesizing images of tau pathology from cross-modal neuroimaging using deep learning. Brain. 2024 Mar 1; 147 (3):980-995
    View PubMed
  108. Taomoto D, Sato S, Kanemoto H, Suzuki M, Hirakawa N, Takasaki A, Akimoto M, Satake Y, Koizumi F, Yoshiyama K, Takahashi R, Shigenobu K, Hashimoto M, Miyagawa T, Boeve B, Knopman D, Mori E, Ikeda M. Utility of the Japanese version of the Clinical Dementia Rating(R) plus National Alzheimer's Coordinating Centre Behaviour and Language Domains for sporadic cases of frontotemporal dementia in Japan. Psychogeriatrics. 2024 Mar; 24 (2):281-294 Epub 2023 Dec 28
    View PubMed
  109. Robinson CG, Lee J, Min PH, Przybelski SA, Josephs KA, Jones DT, Graff-Radford J, Boeve BF, Knopman DS, Jack CR Jr, Petersen RC, Machulda MM, Fields JA, Lowe VJ. Significance of a positive tau PET scan with a negative amyloid PET scan. Alzheimers Dement. 2024 Mar; 20 (3):1923-1932 Epub 2023 Dec 30
    View PubMed
  110. Jack CR Jr, Wiste HJ, Algeciras-Schimnich A, Weigand SD, Figdore DJ, Lowe VJ, Vemuri P, Graff-Radford J, Ramanan VK, Knopman DS, Mielke MM, Machulda MM, Fields J, Schwarz CG, Cogswell PM, Senjem ML, Therneau TM, Petersen RC. Comparison of plasma biomarkers and amyloid PET for predicting memory decline in cognitively unimpaired individuals. Alzheimers Dement. 2024 Mar; 20(3):2143-2154. Epub 2024 Jan 24.
    View PubMed
  111. Knopman DS. For a dementia diagnosis, clinical acumen must precede biomarkers. Lancet Neurol. 2024 Mar; 23 (3):225-226
    View PubMed
  112. Cogswell PM, Lundt ES, Therneau TM, Wiste HJ, Graff-Radford J, Algeciras-Schimnich A, Lowe VJ, Mielke MM, Schwarz CG, Senjem ML, Gunter JL, Knopman DS, Vemuri P, Petersen RC, Jack CR Jr. Modeling the temporal evolution of plasma p-tau in relation to amyloid beta and tau PET. Alzheimers Dement. 2024 Feb; 20 (2):1225-1238 Epub 2023 Nov 14
    View PubMed
  113. Raghavan S, Przybelski SA, Lesnick TG, Fought AJ, Reid RI, Gebre RK, Windham BG, Algeciras-Schimnich A, Machulda MM, Vassilaki M, Knopman DS, Jack CR Jr, Petersen RC, Graff-Radford J, Vemuri P. Vascular risk, gait, behavioral, and plasma indicators of VCID. Alzheimers Dement. 2024 Feb; 20 (2):1201-1213 Epub 2023 Nov 06
    View PubMed
  114. Corriveau-Lecavalier N, Tosakulwong N, Lesnick TG, Fought AJ, Reid RI, Schwarz CG, Senjem ML, Jack CR Jr, Jones DT, Vemuri P, Rademakers R, Ramos EM, Geschwind DH, Knopman DS, Botha H, Savica R, Graff-Radford J, Ramanan VK, Fields JA, Graff-Radford N, Wszolek Z, Forsberg LK, Petersen RC, Heuer HW, Boxer AL, Rosen HJ, Boeve BF, Kantarci K, ALLFTD consortium. Neurite-based white matter alterations in MAPT mutation carriers: A multi-shell diffusion MRI study in the ALLFTD consortium. Neurobiol Aging. 2024 Feb; 134:135-145 Epub 2023 Dec 10
    View PubMed
  115. Gunter NB, Gebre RK, Graff-Radford J, Heckman MG, Jack CR Jr, Lowe VJ, Knopman DS, Petersen RC, Ross OA, Vemuri P, Ramanan VK, Alzheimer's Disease Neuroimaging Initiative. Machine Learning Models of Polygenic Risk for Enhanced Prediction of Alzheimer Disease Endophenotypes. Neurol Genet. 2024 Feb; 10 (1):e200120 Epub 2024 Jan 10
    View PubMed
  116. Stricker NH, Stricker JL, Frank RD, Fan WZ, Christianson TJ, Patel JS, Karstens AJ, Kremers WK, Machulda MM, Fields JA, Graff-Radford J, Jack CR Jr, Knopman DS, Mielke MM, Petersen RC. Stricker Learning Span criterion validity: a remote self-administered multi-device compatible digital word list memory measure shows similar ability to differentiate amyloid and tau PET-defined biomarker groups as in-person Auditory Verbal Learning Test. J Int Neuropsychol Soc. 2024 Feb; 30 (2):138-151 Epub 2023 June 30
    View PubMed
  117. Shir D, Corriveau-Lecavalier N, Graff-Radford J, Machulda MM, Knopman DS, Petersen RC, Nguyen AT, Dickson DW, Jones DT. Case report: pre-symptomatic clinical and metabolic profile in posterior cortical atrophy and dementia with Lewy bodies. Neurocase. 2024 Feb; 30 (1):1-7 Epub 2024 May 17
    View PubMed
  118. Mei H, Simino J, Li L, Jiang F, Bis JC, Davies G, Hill WD, Xia C, Gudnason V, Yang Q, Lahti J, Smith JA, Kirin M, De Jager P, Armstrong NJ, Ghanbari M, Kolcic I, Moran C, Teumer A, Sargurupremraj M, Mahmud S, Fornage M, Zhao W, Satizabal CL, Polasek O, Raikkonen K, Liewald DC, Homuth G, Callisaya M, Mather KA, Windham BG, Zemunik T, Palotie A, Pattie A, van der Auwera S, Thalamuthu A, Knopman DS, Rudan I, Starr JM, Wittfeld K, Kochan NA, Griswold ME, Vitart V, Brodaty H, Gottesman R, Cox SR, Psaty BM, Boerwinkle E, Chasman DI, Grodstein F, Sachdev PS, Srikanth V, Hayward C, Wilson JF, Eriksson JG, Kardia SLR, Grabe HJ, Bennett DA, Ikram MA, Deary IJ, van Duijn CM, Launer L, Fitzpatrick AL, Seshadri S, Bressler J, Debette S, Mosley TH Jr. Multi-omics and pathway analyses of genome-wide associations implicate regulation and immunity in verbal declarative memory performance. Alzheimers Res Ther. 2024 Jan 20; 16 (1):14
    View PubMed
  119. Marks JD, Ayuso VE, Carlomagno Y, Yue M, Todd TW, Hao Y, Li Z, McEachin ZT, Shantaraman A, Duong DM, Daughrity LM, Jansen-West K, Shao W, Calliari A, Bejarano JG, DeTure M, Rawlinson B, Casey MC, Lilley MT, Donahue MH, Jawahar VM, Boeve BF, Petersen RC, Knopman DS, Oskarsson B, Graff-Radford NR, Wszolek ZK, Dickson DW, Josephs KA, Qi YA, Seyfried NT, Ward ME, Zhang YJ, Prudencio M, Petrucelli L, Cook CN. TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia. Sci Transl Med. 2024 Jan 17; 16 (730):eadf9735
    View PubMed
  120. Krell-Roesch J, Syrjanen JA, Bezold J, Trautwein S, Barisch-Fritz B, Boes K, Woll A, Forzani E, Kremers WK, MacHulda MM, Mielke MM, Knopman DS, Petersen RC, Vassilaki M, Geda YE. Physical activity and trajectory of cognitive change in older persons: Mayo Clinic study of aging. Advances in Alzheimer's Disease. 2024; 10:3-14
  121. Corriveau-Lecavalier N, Barnard LR, Przybelski SA, Gogineni V, Botha H, Graff-Radford J, Ramanan VK, Forsberg LK, Fields JA, Machulda MM, Rademakers R, Gavrilova RH, Lapid MI, Boeve BF, Knopman DS, Lowe VJ, Petersen RC, Jack CR, Kantarci K, Jones DT. Assessing network degeneration and phenotypic heterogeneity in genetic frontotemporal lobar degeneration by decoding FDG-PET. Neuroimage Clin. 2024; 41:103559 Epub 2023 Dec 22
    View PubMed
  122. Wang Y, Sharrett AR, Schneider ALC, Knopman D, Hu J, Gottesman R, Sullivan KJ, Coresh J. Timing of Cognitive Test Score Decline Prior to Incident Dementia Diagnosis in Blacks and Whites: The Atherosclerosis Risk in Communities Neurocognitive Study. Neuroepidemiology. 2024; 58 (1):23-30 Epub 2023 Nov 02
    View PubMed
  123. Figdore DJ, Wiste HJ, Bornhorst JA, Bateman RJ, Li Y, Graff-Radford J, Knopman DS, Vemuri P, Lowe VJ, Jr CRJ, Petersen RC, Algeciras-Schimnich A. Performance of the Lumipulse plasma Abeta42/40 and pTau181 immunoassays in the detection of amyloid pathology. Alzheimers Dement (Amst). 2024 Jan-Mar; 16 (1):e12545 Epub 2024 Jan 31
    View PubMed
  124. Boots EA, Frank RD, Fan WZ, Christianson TJ, Kremers WK, Stricker JL, Machulda MM, Fields JA, Hassenstab J, Graff-Radford J, Vemuri P, Jack CR, Knopman DS, Petersen RC, Stricker NH. Continuous Associations between Remote Self-Administered Cognitive Measures and Imaging Biomarkers of Alzheimer's Disease. J Prev Alzheimers Dis. 2024; 11 (5):1467-1479
    View PubMed
  125. Gebre RK, Graff-Radford J, Ramanan VK, Raghavan S, Hofrenning EI, Przybelski SA, Nguyen AT, Lesnick TG, Gunter JL, Algeciras-Schimnich A, Knopman DS, Machulda MM, Vassilaki M, Lowe VJ, Jack CR Jr, Petersen RC, Vemuri P. Can integration of Alzheimer's plasma biomarkers with MRI, cardiovascular, genetics, and lifestyle measures improve cognition prediction? Brain Commun. 2024; 6(5):fcae300. Epub 2024 Sep 04.
    View PubMed
  126. Corriveau-Lecavalier N, Botha H, Graff-Radford J, Switzer AR, Przybelski SA, Wiste HJ, Murray ME, Reichard RR, Dickson DW, Nguyen AT, Ramanan VK, McCarter SJ, Boeve BF, Machulda MM, Fields JA, Stricker NH, Nelson PT, Grothe MJ, Knopman DS, Lowe VJ, Petersen RC, Jack CR Jr, Jones DT. Clinical criteria for a limbic-predominant amnestic neurodegenerative syndrome. Brain Commun. 2024; 6 (4):fcae183 Epub 2024 July 17
    View PubMed
  127. Stricker NH, Christianson TJ, Pudumjee SB, Polsinelli AJ, Lundt ES, Frank RD, Kremers WK, Machulda MM, Fields JA, Jack CR, Knopman DS, Graff-Radford J, Vemuri P, Mielke MM, Petersen RC. Mayo Normative Studies: Amyloid and Neurodegeneration Negative Normative Data for the Auditory Verbal Learning Test and Sex-Specific Sensitivity to Mild Cognitive Impairment/Dementia. J Alzheimers Dis. 2024; 100 (3):879-897
    View PubMed
  128. Syrjanen JA, Krell-Roesch J, Kremers WK, Fields JA, Scharf EL, Knopman DS, Petersen RC, Vassilaki M, Geda YE. Association of Anxiety and Unspecified Emotional Distress Obtained from a Medical Records Linkage System with Incident Cognitive Outcomes in a Population-Based Setting. J Alzheimers Dis. 2024; 100 (4):1355-1364
    View PubMed
  129. Shir D, Graff-Radford J, Fought AJ, Lesnick TG, Przybelski SA, Vassilaki M, Lowe VJ, Knopman DS, Machulda MM, Petersen RC, Jack CR Jr, Mielke MM, Vemuri P. Complex relationships of socioeconomic status with vascular and Alzheimer's pathways on cognition. Neuroimage Clin. 2024; 43:103634 Epub 2024 June 15
    View PubMed
  130. Knopman DS, Laskowitz DT, Koltai DC, Charvet LE, Becker JH, Federman AD, Wisnivesky J, Mahncke H, Van Vleet TM, Bateman L, Kim DY, O'Steen A, James M, Silverstein A, Lokhnygina Y, Rich J, Feger BJ, Zimmerman KO. Recover-neuro: study protocol for a multi-center, multi-arm, phase 2, randomized, active comparator trial evaluating three interventions for cognitive dysfunction in post-acute sequelae of sars-cov-2 infection (pasc). Trials. 2024; 25 (1):326
  131. Gunter J, Shirzadi Z, Schultz SA, Yau WW, Joseph-Mathurin N, Fitzpatrick CD, Levin R, Kantarci K, Preboske GM, Jack CR Jr, Farlow MR, Hassenstab J, Jucker M, Morris JC, Xiong C, Karch CM, Levey AI, Gordon BA, Schofield PR, Salloway SP, Perrin RJ, McDade E, Levin J, Cruchaga C, Allegri RF, Fox NC, Goate A, Day GS, Koeppe R, Chui HC, Berman S, Mori H, Sanchez-Valle R, Lee JH, Rosa-Neto P, Ruthirakuhan M, Wu CY, Swardfager W, Benzinger TLS, Sohrabi HR, Martins RN, Bateman RJ, Johnson KA, Sperling RA, Greenberg SM, Schultz AP, Chhatwal JP, Dominantly Inherited Alzheimer Network and the Alzheimer's Disease Neuroimaging Initiative. Etiology of White Matter Hyperintensities in Autosomal Dominant and Sporadic Alzheimer Disease. JAMA Neurol. 2023 Dec 1; 80 (12):1353-1363
    View PubMed
  132. Pittock RR, Aakre JA, Castillo AM, Ramanan VK, Kremers WK, Jack CR Jr, Vemuri P, Lowe VJ, Knopman DS, Petersen RC, Graff-Radford J, Vassilaki M. Eligibility for Anti-Amyloid Treatment in a Population-Based Study of Cognitive Aging. Neurology. 2023 Nov 7; 101 (19):e1837-e1849 Epub 2023 Aug 16
    View PubMed
  133. Ramanan VK, Gebre RK, Graff-Radford J, Hofrenning E, Algeciras-Schimnich A, Figdore DJ, Lowe VJ, Mielke MM, Knopman DS, Ross OA, Jack CR Jr, Petersen RC, Vemuri P. Genetic risk scores enhance the diagnostic value of plasma biomarkers of brain amyloidosis. Brain. 2023 Nov 2; 146 (11):4508-4519
    View PubMed
  134. Mielke MM, Dage JL, Frank RD, Algeciras-Schimnich A, Knopman DS, Lowe VJ, Bu G, Vemuri P, Graff-Radford J, Jack CR Jr, Petersen RC. Author Correction: Performance of plasma phosphorylated tau 181 and 217 in the community. Nat Med. 2023 Nov; 29 (11):2954
    View PubMed
  135. Deal JA, Jiang K, Rawlings A, Sharrett AR, Reed NS, Knopman D, Mosley T, Wong D, Zhou Y, Lin FR, Gottesman RF. Hearing, beta-Amyloid Deposition and Cognitive Test Performance in Black and White Older Adults: The ARIC-PET Study. J Gerontol A Biol Sci Med Sci. 2023 Oct 28; 78 (11):2105-2110
    View PubMed
  136. Ramanan VK, Graff-Radford J, Syrjanen J, Shir D, Algeciras-Schimnich A, Lucas J, Martens YA, Carrasquillo MM, Day GS, Ertekin-Taner N, Lachner C, Willis FB, Knopman DS, Jack CR Jr, Petersen RC, Vemuri P, Graff-Radford N, Mielke MM. Association of Plasma Biomarkers of Alzheimer Disease With Cognition and Medical Comorbidities in a Biracial Cohort. Neurology. 2023 Oct 3; 101 (14):e1402-e1411 Epub 2023 Aug 14
    View PubMed
  137. Knopman DS, Hershey L. Implications of the Approval of Lecanemab for Alzheimer Disease Patient Care: Incremental Step or Paradigm Shift? Neurology. 2023 Oct 3; 101 (14):610-620 Epub 2023 June 09
    View PubMed
  138. Krell-Roesch J, Rakusa M, Syrjanen JA, van Harten AC, Lowe VJ, Jack CR Jr, Kremers WK, Knopman DS, Stokin GB, Petersen RC, Vassilaki M, Geda YE. Association between CSF biomarkers of Alzheimer's disease and neuropsychiatric symptoms: Mayo Clinic Study of Aging. Alzheimers Dement. 2023 Oct; 19 (10):4498-4506 Epub 2022 Feb 09
    View PubMed
  139. Okine DN, Knopman DS, Mosley TH, Wong DF, Johansen MC, Walker KA, Jack CR Jr, Kantarci K, Pike JR, Graff-Radford J, Gottesman RF. Cerebral Microbleed Patterns and Cortical Amyloid-beta: The ARIC-PET Study. Stroke. 2023 Oct; 54 (10):2613-2620 Epub 2023 Aug 28
    View PubMed
  140. Shrestha S, Zhu X, Sullivan KJ, Blackshear C, Deal JA, Sharrett AR, Kamath V, Schneider ALC, Jack CR, Huang J, Palta P, Reid RI, Knopman DS, Gottesman RF, Chen H, Windham BG, Griswold ME, Mosley TH Jr. Association of Olfaction and Microstructural Integrity of Brain Tissue in Community-Dwelling Adults: Atherosclerosis Risk in Communities Neurocognitive Study. Neurology. 2023 Sep 26; 101 (13):e1328-e1340 Epub 2023 Aug 04
    View PubMed
  141. Johnson EL, Sullivan KJ, Schneider ALC, Simino J, Mosley TH, Kucharska-Newton A, Knopman DS, Gottesman RF. Association of Plasma Abeta(42)/Abeta(40) Ratio and Late-Onset Epilepsy: Results From the Atherosclerosis Risk in Communities Study. Neurology. 2023 Sep 26; 101 (13):e1319-e1327 Epub 2023 Aug 04
    View PubMed
  142. Lin FR, Pike JR, Albert MS, Arnold M, Burgard S, Chisolm T, Couper D, Deal JA, Goman AM, Glynn NW, Gmelin T, Gravens-Mueller L, Hayden KM, Huang AR, Knopman D, Mitchell CM, Mosley T, Pankow JS, Reed NS, Sanchez V, Schrack JA, Windham BG, Coresh J, ACHIEVE Collaborative Research Group. Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multicentre, randomised controlled trial. Lancet. 2023 Sep 2; 402 (10404):786-797 Epub 2023 July 18
    View PubMed
  143. Walker KA, Hoogeveen RC, Folsom AR, Ballantyne CM, Knopman DS, Windham BG, Jack CR Jr, Gottesman RF. Midlife systemic inflammatory markers are associated with late-life brain volume: the aric study. Neurology. 2023 Aug 22; 101 (8):E856-65
  144. Estades Ayuso V, Pickles S, Todd T, Yue M, Jansen-West K, Song Y, Gonzalez Bejarano J, Rawlinson B, DeTure M, Graff-Radford NR, Boeve BF, Knopman DS, Petersen RC, Dickson DW, Josephs KA, Petrucelli L, Prudencio M. TDP-43-regulated cryptic RNAs accumulate in Alzheimer's disease brains. Mol Neurodegener. 2023 Aug 21; 18 (1):57
    View PubMed
  145. Grossman M, Seeley WW, Boxer AL, Hillis AE, Knopman DS, Ljubenov PA, Miller B, Piguet O, Rademakers R, Whitwell JL, Zetterberg H, van Swieten JC. Frontotemporal lobar degeneration. Nat Rev Dis Primers. 2023 Aug 10; 9 (1):40
    View PubMed
  146. Schwarz CG, Kremers WK, Arani A, Savvides M, Reid RI, Gunter JL, Senjem ML, Cogswell PM, Vemuri P, Kantarci K, Knopman DS, Petersen RC, Jack CR Jr, Alzheimer's Disease Neuroimaging Initiative. A face-off of MRI research sequences by their need for de-facing. Neuroimage. 2023 Aug 1; 276:120199 Epub 2023 June 01
    View PubMed
  147. Smith JR, Sharrett AR, Pike JR, Gottesman RF, Knopman DS, Lee M, Lutsey PL, Palta P, Windham BG, Coresh J, Deal JA. Dementia occurring over a 32-year follow-up attributable to hypertension observed at different ages: Implications for dementia prevention. Alzheimers Dement. 2023 Aug; 19 (8):3435-3447 Epub 2023 Feb 18
    View PubMed
  148. Shir D, Pham NTT, Botha H, Koga S, Kouri N, Ali F, Knopman DS, Petersen RC, Boeve BF, Kremers WK, Nguyen AT, Murray ME, Reichard RR, Dickson DW, Graff-Radford N, Josephs KA, Whitwell J, Graff-Radford J. Clinicoradiologic and Neuropathologic Evaluation of Corticobasal Syndrome. Neurology. 2023 Jul 18; 101 (3):e289-e299 Epub 2023 June 02
    View PubMed
  149. Diaz-Galvan P, Przybelski SA, Lesnick TG, Schwarz CG, Senjem ML, Gunter JL, Jack CR, Min HP, Jain M, Miyagawa T, Forsberg LK, Fields JA, Savica R, Graff-Radford J, Jones DT, Botha H, St Louis EK, Knopman DS, Ramanan VK, Ross O, Graff-Radford N, Day GS, Dickson DW, Ferman TJ, Petersen RC, Lowe VJ, Boeve BF, Kantarci K. beta-Amyloid Load on PET Along the Continuum of Dementia With Lewy Bodies. Neurology. 2023 Jul 11; 101 (2):e178-e188 Epub 2023 May 18
    View PubMed
  150. Krell-Roesch J, Zaniletti I, Syrjanen JA, Kremers WK, Algeciras-Schimnich A, Dage JL, van Harten AC, Fields JA, Knopman DS, Jack CR Jr, Petersen RC, Vassilaki M, Geda YE. Plasma-derived biomarkers of Alzheimer's disease and neuropsychiatric symptoms: A community-based study. Alzheimers Dement (Amst). 2023 Jul-Sep; 15 (3):e12461 Epub 2023 July 30
    View PubMed
  151. Bermudez C, Graff-Radford J, Syrjanen JA, Stricker NH, Algeciras-Schimnich A, Kouri N, Kremers WK, Petersen RC, Jack CR Jr, Knopman DS, Dickson DW, Nguyen AT, Reichard RR, Murray ME, Mielke MM, Vemuri P. Plasma biomarkers for prediction of Alzheimer's disease neuropathologic change. Acta Neuropathol. 2023 Jul; 146 (1):13-29 Epub 2023 June 03
    View PubMed
  152. Carlos AF, Tosakulwong N, Weigand SD, Senjem ML, Schwarz CG, Knopman DS, Boeve BF, Petersen RC, Nguyen AT, Reichard RR, Dickson DW, Jack CR Jr, Lowe V, Whitwell JL, Josephs KA. TDP-43 pathology effect on volume and flortaucipir uptake in Alzheimer's disease. Alzheimers Dement. 2023 Jun; 19 (6):2343-2354 Epub 2022 Dec 04
    View PubMed
  153. Stricker NH, Twohy EL, Albertson SM, Karstens AJ, Kremers WK, Machulda MM, Fields JA, Jack CR Jr, Knopman DS, Mielke MM, Petersen RC. Mayo-PACC: A parsimonious preclinical Alzheimer's disease cognitive composite comprised of public-domain measures to facilitate clinical translation. Alzheimers Dement. 2023 Jun; 19 (6):2575-2584 Epub 2022 Dec 24
    View PubMed
  154. Tian J, Raghavan S, Reid RI, Przybelski SA, Lesnick TG, Gebre RK, Graff-Radford J, Schwarz CG, Lowe VJ, Kantarci K, Knopman DS, Petersen RC, Jack CR Jr, Vemuri P. White Matter Degeneration Pathways Associated With Tau Deposition in Alzheimer Disease. Neurology. 2023 May 30; 100 (22):e2269-e2278 Epub 2023 Apr 17
    View PubMed
  155. Cogswell PM, Lundt ES, Therneau TM, Mester CT, Wiste HJ, Graff-Radford J, Schwarz CG, Senjem ML, Gunter JL, Reid RI, Przybelski SA, Knopman DS, Vemuri P, Petersen RC, Jack CR Jr. Evidence against a temporal association between cerebrovascular disease and Alzheimer's disease imaging biomarkers. Nat Commun. 2023 May 29; 14 (1):3097
    View PubMed
  156. Corriveau-Lecavalier N, Barnard LR, Lee J, Dicks E, Botha H, Graff-Radford J, Machulda MM, Boeve BF, Knopman DS, Lowe VJ, Petersen RC, Jack CR Jr, Jones DT. Deciphering the clinico-radiological heterogeneity of dysexecutive Alzheimer's disease. Cereb Cortex. 2023 May 24; 33 (11):7026-7043
    View PubMed
  157. Barkhof F, Knopman DS. Brain Shrinkage in Anti-beta-Amyloid Alzheimer Trials: Neurodegeneration or Pseudoatrophy? Neurology 2023 May 16; 100 (20):941-942 Epub 2023 Mar 27
    View PubMed
  158. Jack CR, Wiste HJ, Algeciras-Schimnich A, Figdore DJ, Schwarz CG, Lowe VJ, Ramanan VK, Vemuri P, Mielke MM, Knopman DS, Graff-Radford J, Boeve BF, Kantarci K, Cogswell PM, Senjem ML, Gunter JL, Therneau TM, Petersen RC. Predicting amyloid PET and tau PET stages with plasma biomarkers. Brain. 2023 May 2; 146 (5):2029-2044
    View PubMed
  159. Sedaghat S, Lutsey PL, Ji Y, Empana JP, Sorond F, Hughes TM, Mosley TH, Gottesman RF, Knopman DS, Walker KA, Gudnason V, Launer LJ, van Sloten TT. Association of change in cardiovascular risk factors with incident dementia. Alzheimers Dement. 2023 May; 19 (5):1821-1831 Epub 2022 Oct 27
    View PubMed
  160. Gebre RK, Senjem ML, Raghavan S, Schwarz CG, Gunter JL, Hofrenning EI, Reid RI, Kantarci K, Graff-Radford J, Knopman DS, Petersen RC, Jack CR Jr, Vemuri P. Cross-scanner harmonization methods for structural MRI may need further work: A comparison study. Neuroimage. 2023 Apr 1; 269:119912 Epub 2023 Jan 31
    View PubMed
  161. Knopman DS. Lecanemab reduces brain amyloid-beta and delays cognitive worsening. Cell Rep Med. 2023 Mar 21; 4 (3):100982
    View PubMed
  162. Patricia Diaz-Galvan, Scott A. Przybelski, Timothy G. Lesnick, Christopher G. Schwarz, Matthew L. Senjem, Jeffrey Gunter, Clifford R. Jack Jr, Paul H. Min , Manoj K. Jain , Toji Miyagawa , Leah K. Forsberg, Julie A. Fields , Rodolfo Savica , Jonathan Graff-Radford , David T. Jones , Hugo Botha , Erik K. St. Louis , David S. Knopman , Owen A. Ross , Neill Graff-Radford, Dennis W. Dickson , Tanis J. Ferman , Ronald C. Petersen , Val Lowe , Brad Boeve , Kejal Kantarci . Amyloid-ß PET in the continuum of dementia of Lewy Bodies Neurology. 2023.
  163. Vassilaki M, Aakre JA, Castillo A, Chamberlain AM, Wilson PM, Kremers WK, Mielke MM, Geda YE, Machulda MM, Alhurani RE, Graff-Radford J, Vemuri P, Lowe VJ, Jack CR Jr, Knopman DS, Petersen RC. Association of neighborhood socioeconomic disadvantage and cognitive impairment. Alzheimers Dement. 2023 Mar; 19 (3):761-770 Epub 2022 June 06
    View PubMed
  164. Krell-Roesch J, Syrjanen JA, Bezold J, Trautwein S, Barisch-Fritz B, Kremers WK, Fields JA, Scharf EL, Knopman DS, Stokin GB, Petersen RC, Jekauc D, Woll A, Vassilaki M, Geda YE. Mid- and Late-Life Physical Activity and Neuropsychiatric Symptoms in Dementia-Free Older Adults: Mayo Clinic Study of Aging. J Neuropsychiatry Clin Neurosci. 2023 Spring; 35 (2):133-140 Epub 2022 Dec 05
    View PubMed
  165. Pink A, Krell-Roesch J, Syrjanen JA, Christenson LR, Lowe VJ, Vemuri P, Fields JA, Stokin GB, Kremers WK, Scharf EL, Jack CR Jr, Knopman DS, Petersen RC, Vassilaki M, Geda YE. Interactions Between Neuropsychiatric Symptoms and Alzheimer's Disease Neuroimaging Biomarkers in Predicting Longitudinal Cognitive Decline. Psychiatr Res Clin Pract. 2023 Spring; 5 (1):4-15 Epub 2023 Jan 20
    View PubMed
  166. Scheppach JB, Wu A, Gottesman RF, Mosley TH, Arsiwala-Scheppach LT, Knopman DS, Grams ME, Sharrett AR, Coresh J, Koton S. Association of Kidney Function Measures With Signs of Neurodegeneration and Small Vessel Disease on Brain Magnetic Resonance Imaging: The Atherosclerosis Risk in Communities (ARIC) Study. Am J Kidney Dis. 2023 Mar; 81 (3):261-269.e1 Epub 2022 Sept 27
    View PubMed
  167. Ducca EL, Gomez GT, Palta P, Sullivan KJ, Jack CR, Knopman DS, Gottesman RF, Walston J, Windham BG, Walker KA. Physical Frailty and Brain White Matter Abnormalities: The Atherosclerosis Risk in Communities Study. J Gerontol A Biol Sci Med Sci. 2023 Feb 24; 78 (2):357-364
    View PubMed
  168. Sprung J, Laporta ML, Knopman DS, Petersen RC, Mielke MM, Jack CR, Martin DP, Hanson AC, Schroeder DR, Schulte PJ, Przybelski SA, Valencia Morales DJ, Weingarten TN, Vemuri P, Warner DO. Association of Indication for Hospitalization With Subsequent Amyloid Positron Emission Tomography and Magnetic Resonance Imaging Biomarkers. J Gerontol A Biol Sci Med Sci. 2023 Feb 24; 78 (2):304-313
    View PubMed
  169. Ferreira D, Przybelski SA, Lesnick TG, Schwarz CG, Diaz-Galvan P, Graff-Radford J, Senjem ML, Fields JA, Knopman DS, Jones DT, Savica R, Ferman TJ, Lowe VJ, Jack CR, Petersen RC, Westman E, Boeve BF, Kantarci K. Cross-sectional Associations of beta-Amyloid, Tau, and Cerebrovascular Biomarkers With Neurodegeneration in Probable Dementia With Lewy Bodies. Neurology. 2023 Feb 21; 100 (8):e846-e859 Epub 2022 Nov 28
    View PubMed
  170. Warner NS, Mielke MM, Verdoorn BP, Knopman DS, Hooten WM, Habermann EB, Warner DO. Pain, Opioid Analgesics, and Cognition: A Conceptual Framework in Older Adults. Pain Med. 2023 Feb 1; 24 (2):171-181
    View PubMed
  171. Buciuc M, Koga S, Pham NTT, Duffy JR, Knopman DS, Ali F, Boeve BF, Graff-Radford J, Botha H, Lowe VJ, Nguyen A, Reichard RR, Dickson DW, Petersen RC, Whitwell JL, Josephs KA. The many faces of globular glial tauopathy: A clinical and imaging study. Eur J Neurol. 2023 Feb; 30(2):321-333. Epub 2022 Nov 01.
    View PubMed
  172. Fautsch KJ, Block DR, Graff-Radford J, Wang F, Craver EC, Hodge DO, Cutsforth-Gregory JK, Kilgore KP, Petersen RC, Knopman DS, Flanagan E, Toledano M, Mielke MM, Bhatti MT, Chen JJ. Population-Based Evaluation of Total Protein in Cerebrospinal Fluid. Mayo Clin Proc. 2023 Feb; 98(2):239-251.
    View PubMed
  173. Grossman M, Seeley WW, Boxer AL, Hillis AE, Knopman DS, Ljubenov PA, Miller B, Piguet O, Rademakers R, Whitwell JL, Zetterberg H, van Swieten JC. Frontotemporal lobar degeneration. Nature Reviews. Disease Primers. 2023; 9 (1):40
  174. Schwarz CG, Kremers WK, Weigand SD, Prakaashana CM, Senjem ML, Przybelski SA, Lowe VJ, Gunter JL, Kantarci K, Vemuri P, Graff-Radford J, Petersen RC, Knopman DS, Jack CR Jr. Effects of de-facing software mri_reface on utility of imaging biomarkers used in Alzheimer's disease research. Neuroimage Clin. 2023; 40:103507 Epub 2023 Sept 09
    View PubMed
  175. Vassilaki M, Syrjanen JA, Krell-Roesch J, Graff-Radford J, Vemuri P, Scharf EL, Machulda MM, Fields JA, Kremers WK, Lowe VJ, Jack CR Jr, Knopman DS, Petersen RC, Geda YE. Association of Cerebrovascular Imaging Biomarkers, Depression, and Anxiety, with Mild Cognitive Impairment. J Alzheimers Dis Rep. 2023; 7 (1):1237-1246 Epub 2023 Nov 03
    View PubMed
  176. Lilek J, Ajroud K, Feldman AZ, Krishnamachari S, Ghourchian S, Gefen T, Spencer CL, Kawles A, Mao Q, Tranovich JF, Jack CR, Mesulam MM, Reichard RR, Zhang H, Murray ME, Knopman D, Dickson DW, Petersen RC, Smith B, Ashe KH, Mielke MM, Nelson KM, Flanagan ME. Accumulation of pTau231 at the Postsynaptic Density in Early Alzheimer's Disease. J Alzheimers Dis. 2023; 92 (1):241-260
    View PubMed
  177. Pavuluri K, Scott JM, Huston Iii J, Ehman RL, Manduca A, Jack CR Jr, Savica R, Boeve BF, Kantarci K, Petersen RC, Knopman DS, Murphy MC. Differential effect of dementia etiology on cortical stiffness as assessed by MR elastography. Neuroimage Clin. 2023; 37:103328 Epub 2023 Jan 18
    View PubMed
  178. Shir D, Mielke MM, Hofrenning EI, Lesnick TG, Knopman DS, Petersen RC, Jack CR, Algeciras-Schimnich A, Vemuri P, Graff-Radford J. Associations of Neurodegeneration Biomarkers in Cerebrospinal Fluid with Markers of Alzheimer's Disease and Vascular Pathology. J Alzheimers Dis. 2023; 92 (3):887-898
    View PubMed
  179. Corriveau-Lecavalier N, Gunter JL, Kamykowski M, Dicks E, Botha H, Kremers WK, Graff-Radford J, Wiepert DA, Schwarz CG, Yacoub E, Knopman DS, Boeve BF, Ugurbil K, Petersen RC, Jack CR, Terpstra MJ, Jones DT. Default mode network failure and neurodegeneration across aging and amnestic and dysexecutive Alzheimer's disease. Brain Commun. 2023; 5 (2):fcad058 Epub 2023 Mar 08
    View PubMed
  180. Sprung J, Laporta ML, Knopman DS, Petersen RC, Mielke MM, Jack CR Jr, Martin DP, Hanson AC, Schroeder DR, Schulte PJ, Przybelski SA, Valencia Morales DJ, Weingarten TN, Vemuri P, Warner DO. Association of indication for hospitalization with subsequent amyloid positron emission tomography and magnetic resonance imaging biomarkers. Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 2023; 78 (2):304-13
  181. Ducca EL, Gomez GT, Palta P, Sullivan KJ, Jack CR Jr, Knopman DS, Gottesman RF, Walston J, Windham BG, Walker KA. Physical frailty and brain white matter abnormalities: the atherosclerosis risk in communities study. Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 2023; 78 (2):357-64
  182. Murray ME, Moloney CM, Kouri N, Syrjanen JA, Matchett BJ, Rothberg DM, Tranovich JF, Sirmans TNH, Wiste HJ, Boon BDC, Nguyen AT, Reichard RR, Dickson DW, Lowe VJ, Dage JL, Petersen RC, Jack CR Jr, Knopman DS, Vemuri P, Graff-Radford J, Mielke MM. Global neuropathologic severity of Alzheimer's disease and locus coeruleus vulnerability influences plasma phosphorylated tau levels. Mol Neurodegener. 2022 Dec 27; 17 (1):85
    View PubMed
  183. Nguyen AT, Kouri N, Labuzan SA, Przybelski SA, Lesnick TG, Raghavan S, Reid RI, Reichard RR, Knopman DS, Petersen RC, Jack CR Jr, Mielke MM, Dickson DW, Graff-Radford J, Murray ME, Vemuri P. Neuropathologic scales of cerebrovascular disease associated with diffusion changes on MRI. Acta Neuropathol. 2022 Dec; 144 (6):1117-1125 Epub 2022 July 16
    View PubMed
  184. Graff-Radford J, Mielke MM, Hofrenning EI, Kouri N, Lesnick TG, Moloney CM, Rabinstein A, Cabrera-Rodriguez JN, Rothberg DM, Przybelski SA, Petersen RC, Knopman DS, Dickson DW, Jack CR, Algeciras-Schimnich A, Nguyen AT, Murray ME, Vemuri P. Association of plasma biomarkers of amyloid and neurodegeneration with cerebrovascular disease and Alzheimer's disease. Neurobiol Aging. 2022 Nov; 119:1-7 Epub 2022 July 24
    View PubMed
  185. Pham NTT, Graff-Radford J, Machulda MM, Spychalla AJ, Schwarz CG, Senjem ML, Lowe VJ, Vemuri P, Kantarci K, Knopman DS, Petersen RC, Jack CR, Josephs KA, Whitwell JL. Regional white matter hyperintensities in posterior cortical atrophy and logopenic progressive aphasia. Neurobiol Aging. 2022 Nov; 119:46-55 Epub 2022 July 28
    View PubMed
  186. Lee J, Burkett BJ, Min HK, Lundt ES, Albertson SM, Botha H, Senjem ML, Gunter JL, Schwarz CG, Jones DT, Knopman DS, Jack CR Jr, Petersen RC, Lowe VJ. The Overlap Index as a Means of Evaluating Early Tau PET Signal Reliability. J Nucl Med. 2022 Nov; 63 (11):1748-1753 Epub 2022 Mar 17
    View PubMed
  187. Vassilaki M, Kremers WK, Machulda MM, Knopman DS, Petersen RC, Laporta ML, Berry DJ, Lewallen DG, Maradit Kremers H. Long-term Cognitive Trajectory After Total Joint Arthroplasty. JAMA Netw Open. 2022 Nov 1; 5 (11):e2241807 Epub 2022 Nov 01
    View PubMed
  188. Pink A, Krell-Roesch J, Syrjanen JA, Vassilaki M, Lowe VJ, Vemuri P, Stokin GB, Christianson TJ, Kremers WK, Jack CR, Knopman DS, Petersen RC, Geda YE. A longitudinal investigation of Abeta, anxiety, depression, and mild cognitive impairment. Alzheimers Dement. 2022 Oct; 18 (10):1824-1831 Epub 2021 Dec 08
    View PubMed
  189. Garbajs NZ, Singh TD, Valencia Morales DJ, Herasevich V, Warner DO, Martin DP, Knopman DS, Petersen RC, Hanson AC, Jennissen AJ, Schroeder DR, Weingarten TN, Gajic O, Rabinstein AA, Sprung J. Association of blood pressure variability with short- and long-term cognitive outcomes in patients with critical illness. J Crit Care. 2022 Oct; 71:154107 Epub 2022 July 06
    View PubMed
  190. Gottesman RF, Wu A, Coresh J, Knopman DS, Jack CR Jr, Rahmim A, Sharrett AR, Spira AP, Wong DF, Wagenknecht LE, Hughes TM, Walker KA, Mosley TH. Associations of Vascular Risk and Amyloid Burden with Subsequent Dementia. Ann Neurol. 2022 Oct; 92 (4):607-619 Epub 2022 Aug 03
    View PubMed
  191. Chang BK, Day GS, Graff-Radford J, McKeon A, Flanagan EP, Algeciras-Schimnich A, Mielke MM, Nguyen A, Jones DT, Toledano M, Kremers WK, Knopman DS, Petersen RC, Li W. Alzheimer's disease cerebrospinal fluid biomarkers differentiate patients with Creutzfeldt-Jakob disease and autoimmune encephalitis. Eur J Neurol. 2022 Oct; 29 (10):2905-2912 Epub 2022 July 05
    View PubMed
  192. Staffaroni AM, Quintana M, Wendelberger B, Heuer HW, Russell LL, Cobigo Y, Wolf A, Goh SM, Petrucelli L, Gendron TF, Heller C, Clark AL, Taylor JC, Wise A, Ong E, Forsberg L, Brushaber D, Rojas JC, VandeVrede L, Ljubenkov P, Kramer J, Casaletto KB, Appleby B, Bordelon Y, Botha H, Dickerson BC, Domoto-Reilly K, Fields JA, Foroud T, Gavrilova R, Geschwind D, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grossman M, Hall MGH, Hsiung GY, Huey ED, Irwin D, Jones DT, Kantarci K, Kaufer D, Knopman D, Kremers W, Lago AL, Lapid MI, Litvan I, Lucente D, Mackenzie IR, Mendez MF, Mester C, Miller BL, Onyike CU, Rademakers R, Ramanan VK, Ramos EM, Rao M, Rascovsky K, Rankin KP, Roberson ED, Savica R, Tartaglia MC, Weintraub S, Wong B, Cash DM, Bouzigues A, Swift IJ, Peakman G, Bocchetta M, Todd EG, Convery RS, Rowe JB, Borroni B, Galimberti D, Tiraboschi P, Masellis M, Finger E, van Swieten JC, Seelaar H, Jiskoot LC, Sorbi S, Butler CR, Graff C, Gerhard A, Langheinrich T, Laforce R, Sanchez-Valle R, de Mendonca A, Moreno F, Synofzik M, Vandenberghe R, Ducharme S, Le Ber I, Levin J, Danek A, Otto M, Pasquier F, Santana I, Kornak J, Boeve BF, Rosen HJ, Rohrer JD, Boxer AL, Frontotemporal Dementia Prevention Initiative (FPI) Investigators. Temporal order of clinical and biomarker changes in familial frontotemporal dementia. Nat Med. 2022 Oct; 28 (10):2194-2206 Epub 2022 Sept 22
    View PubMed
  193. Tipton PW, Deutschlaender AB, Savica R, Heckman MG, Brushaber DE, Dickerson BC, Gavrilova RH, Geschwind DH, Ghoshal N, Graff-Radford J, Graff-Radford NR, Grossman M, Hsiung GR, Huey ED, Irwin DJ, Jones DT, Knopman DS, McGinnis SM, Rademakers R, Ramos EM, Forsberg LK, Heuer HW, Onyike C, Tartaglia C, Domoto-Reilly K, Roberson ED, Mendez MF, Litvan I, Appleby BS, Grant I, Kaufer D, Boxer AL, Rosen HJ, Boeve BF, Wszolek ZK, ALLFTD Consortium. Differences in Motor Features of C9orf72, MAPT, or GRN Variant Carriers With Familial Frontotemporal Lobar Degeneration. Neurology. 2022 Sep 13; 99 (11):e1154-e1167 Epub 2022 July 05
    View PubMed
  194. Cogswell PM, Wiste HJ, Mielke MM, Schwarz CG, Weigand SD, Lowe VJ, Therneau TM, Knopman DS, Graff-Radford J, Vemuri P, Senjem ML, Gunter JL, Algeciras-Schimnich A, Petersen RC, Jack CR Jr. CSF phosphorylated tau as an indicator of subsequent tau accumulation. Neurobiol Aging. 2022 Sep; 117:189-200 Epub 2022 May 26
    View PubMed
  195. Schwarz CG, Kremers WK, Lowe VJ, Savvides M, Gunter JL, Senjem ML, Vemuri P, Kantarci K, Knopman DS, Petersen RC, Jack CR Jr, Alzheimer's Disease Neuroimaging Initiative. Face recognition from research brain PET: An unexpected PET problem. Neuroimage. 2022 Sep; 258:119357 Epub 2022 June 03
    View PubMed
  196. Johansen MC, Wang W, Zhang M, Knopman DS, Ndumele C, Mosley TH, Selvin E, Shah AM, Solomon SD, Gottesman RF, Chen LY. Risk of Dementia Associated With Atrial Cardiopathy: The ARIC Study. J Am Heart Assoc. 2022 Aug 16; 11 (16):e025646 Epub 2022 Aug 10
    View PubMed
  197. Cogswell PM, Aakre JA, Castillo AM, Knopman DS, Kantarci K, Rabinstein AA, Petersen RC, Jack CR Jr, Mielke MM, Vemuri P, Graff-Radford J. Population-Based Prevalence of Infarctions on 3D Fluid-Attenuated Inversion Recovery (FLAIR) Imaging. J Stroke Cerebrovasc Dis. 2022 Aug; 31 (8):106583 Epub 2022 June 08
    View PubMed
  198. Toller G, Cobigo Y, Ljubenkov PA, Appleby BS, Dickerson BC, Domoto-Reilly K, Fong JC, Forsberg LK, Gavrilova RH, Ghoshal N, Heuer HW, Knopman DS, Kornak J, Lapid MI, Litvan I, Lucente DE, Mackenzie IR, Mckenzie IR, McGinnis SM, Miller BL, Pedraza O, Rojas JC, Staffaroni AM, Wong B, Wszolek ZK, Boeve BF, Boxer AL, Rosen HJ, Rankin KP, and the ALLFTD research consortium. Sensitivity of the Social Behavior Observer Checklist to Early Symptoms of Patients With Frontotemporal Dementia. Neurology. 2022 Aug 1; 99 (5):e488-e499 Epub 2022 Aug 01
    View PubMed
  199. Corriveau-Lecavalier N, Machulda MM, Botha H, Graff-Radford J, Knopman DS, Lowe VJ, Fields JA, Stricker NH, Boeve BF, Jack CR Jr, Petersen RC, Jones DT. Phenotypic subtypes of progressive dysexecutive syndrome due to Alzheimer's disease: a series of clinical cases. J Neurol. 2022 Aug; 269 (8):4110-4128 Epub 2022 Feb 25
    View PubMed
  200. Knopman D, Sano M, Feldman HH. CMS coverage decision on anti-amyloid monoclonal antibodies for Alzheimer disease. Nat Rev Neurol. 2022 Jul; 18 (7):379-380
    View PubMed
  201. Carlos AF, Tosakulwong N, Weigand SD, Boeve BF, Knopman DS, Petersen RC, Nguyen A, Reichard RR, Murray ME, Dickson DW, Josephs KA. Frequency and distribution of TAR DNA-binding protein 43 (TDP-43) pathology increase linearly with age in a large cohort of older adults with and without dementia. Acta Neuropathol. 2022 Jul; 144 (1):159-160 Epub 2022 May 10
    View PubMed
  202. Mielke MM, Dage JL, Frank RD, Algeciras-Schimnich A, Knopman DS, Lowe VJ, Bu G, Vemuri P, Graff-Radford J, Jack CR Jr, Petersen RC. Performance of plasma phosphorylated tau 181 and 217 in the community. Nat Med. 2022 Jul; 28 (7):1398-1405 Epub 2022 May 26
    View PubMed
  203. Nelson PT, Brayne C, Flanagan ME, Abner EL, Agrawal S, Attems J, Castellani RJ, Corrada MM, Cykowski MD, Di J, Dickson DW, Dugger BN, Ervin JF, Fleming J, Graff-Radford J, Grinberg LT, Hokkanen SRK, Hunter S, Kapasi A, Kawas CH, Keage HAD, Keene CD, Kero M, Knopman DS, Kouri N, Kovacs GG, Labuzan SA, Larson EB, Latimer CS, Leite REP, Matchett BJ, Matthews FE, Merrick R, Montine TJ, Murray ME, Myllykangas L, Nag S, Nelson RS, Neltner JH, Nguyen AT, Petersen RC, Polvikoski T, Reichard RR, Rodriguez RD, Suemoto CK, Wang SJ, Wharton SB, White L, Schneider JA. Frequency of LATE neuropathologic change across the spectrum of Alzheimer's disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts. Acta Neuropathol. 2022 Jul; 144 (1):27-44 Epub 2022 June 13
    View PubMed
  204. Mishra A, Duplaa C, Vojinovic D, Suzuki H, Sargurupremraj M, Zilhao NR, Li S, Bartz TM, Jian X, Zhao W, Hofer E, Wittfeld K, Harris SE, van der Auwera-Palitschka S, Luciano M, Bis JC, Adams HHH, Satizabal CL, Gottesman RF, Gampawar PG, Bulow R, Weiss S, Yu M, Bastin ME, Lopez OL, Vernooij MW, Beiser AS, Volker U, Kacprowski T, Soumare A, Smith JA, Knopman DS, Morris Z, Zhu Y, Rotter JI, Dufouil C, Valdes Hernandez M, Munoz Maniega S, Lathrop M, Boerwinkle E, Schmidt R, Ihara M, Mazoyer B, Yang Q, Joutel A, Tournier-Lasserve E, Launer LJ, Deary IJ, Mosley TH, Amouyel P, DeCarli CS, Psaty BM, Tzourio C, Kardia SLR, Grabe HJ, Teumer A, van Duijn CM, Schmidt H, Wardlaw JM, Ikram MA, Fornage M, Gudnason V, Seshadri S, Matthews PM, Longstreth WT, Couffinhal T, Debette S. Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate. Brain. 2022 Jun 30; 145 (6):1992-2007
    View PubMed
  205. Syrjanen JA, Campbell MR, Algeciras-Schimnich A, Vemuri P, Graff-Radford J, Machulda MM, Bu G, Knopman DS, Jack CR Jr, Petersen RC, Mielke MM. Associations of amyloid and neurodegeneration plasma biomarkers with comorbidities. Alzheimers Dement. 2022 Jun; 18 (6):1128-1140 Epub 2021 Sept 27
    View PubMed
  206. Manemann SM, Knopman DS, St Sauver J, Bielinski SJ, Chamberlain AM, Weston SA, Jiang R, Roger VL. Alzheimer's disease and related dementias and heart failure: A community study. J Am Geriatr Soc. 2022 Jun; 70 (6):1664-1672 Epub 2022 Mar 18
    View PubMed
  207. Chen Q, Przybelski SA, Senjem ML, Schwarz CG, Lesnick TG, Botha H, Knopman DS, Graff-Radford J, Savica R, Jones DT, Fields JA, Jain MK, Graff-Radford NR, Ferman TJ, Kremers WK, Jack CR Jr, Petersen RC, Boeve BF, Lowe VJ, Kantarci K. Longitudinal Tau Positron Emission Tomography in Dementia with Lewy Bodies. Mov Disord. 2022 Jun; 37 (6):1256-1264 Epub 2022 Mar 08
    View PubMed
  208. Weil EL, Noseworthy PA, Lopez CL, Rabinstein AA, Friedman PA, Attia ZI, Yao X, Siontis KC, Kremers WK, Christopoulos G, Mielke MM, Vemuri P, Jack CR Jr, Gersh BJ, Machulda MM, Knopman DS, Petersen RC, Graff-Radford J. Artificial Intelligence-Enabled Electrocardiogram for Atrial Fibrillation Identifies Cognitive Decline Risk and Cerebral Infarcts. Mayo Clin Proc. 2022 May; 97 (5):871-880
    View PubMed
  209. Ramanan VK, Heckman MG, Lesnick TG, Przybelski SA, Cahn EJ, Kosel ML, Murray ME, Mielke MM, Botha H, Graff-Radford J, Jones DT, Lowe VJ, Machulda MM, Jack CR Jr, Knopman DS, Petersen RC, Ross OA, Vemuri P. Tau polygenic risk scoring: a cost-effective aid for prognostic counseling in Alzheimer's disease. Acta Neuropathol. 2022 May; 143 (5):571-583 Epub 2022 Apr 12
    View PubMed
  210. Wang W, Norby FL, Alonso A, Gottesman RF, Jack CR Jr, Meyer ML, Knopman DS, Sullivan KJ, Hughes TM, Lakshminarayan K, Lutsey PL. Association of Carotid Intima-Media Thickness with Brain MRI Markers in the Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS). J Stroke Cerebrovasc Dis. 2022 May; 31 (5):106388 Epub 2022 Feb 19
    View PubMed
  211. Saboo KV, Hu C, Varatharajah Y, Przybelski SA, Reid RI, Schwarz CG, Graff-Radford J, Knopman DS, Machulda MM, Mielke MM, Petersen RC, Arnold PM, Worrell GA, Jones DT, Jack CR Jr, Iyer RK, Vemuri P. Deep learning identifies brain structures that predict cognition and explain heterogeneity in cognitive aging. Neuroimage. 2022 May 1; 251:119020 Epub 2022 Feb 20
    View PubMed
  212. Lee J, Burkett BJ, Min HK, Senjem ML, Lundt ES, Botha H, Graff-Radford J, Barnard LR, Gunter JL, Schwarz CG, Kantarci K, Knopman DS, Boeve BF, Lowe VJ, Petersen RC, Jack CR Jr, Jones DT. Deep learning-based brain age prediction in normal aging and dementia. Nat Aging. 2022 May; 2 (5):412-424 Epub 2022 May 09
    View PubMed
  213. Li C, Knopman D, Xu W, Cohen T, Pakhomov S. GPT-D: Inducing Dementia-related Linguistic Anomalies by Deliberate Degradation of Artificial Neural Language Models. Proc Conf Assoc Comput Linguist Meet. 2022 May; 2022:1866-1877
    View PubMed
  214. Barker MS, Gottesman RT, Manoochehri M, Chapman S, Appleby BS, Brushaber D, Devick KL, Dickerson BC, Domoto-Reilly K, Fields JA, Forsberg LK, Galasko DR, Ghoshal N, Goldman J, Graff-Radford NR, Grossman M, Heuer HW, Hsiung GY, Knopman DS, Kornak J, Litvan I, Mackenzie IR, Masdeu JC, Mendez MF, Pascual B, Staffaroni AM, Tartaglia MC, Boeve BF, Boxer AL, Rosen HJ, Rankin KP, Cosentino S, Rascovsky K, Huey ED, ALLFTD Consortium. Proposed research criteria for prodromal behavioural variant frontotemporal dementia. Brain. 2022 Apr 29; 145 (3):1079-1097
    View PubMed
  215. Kara F, Joers JM, Deelchand DK, Park YW, Przybelski SA, Lesnick TG, Senjem ML, Zeydan B, Knopman DS, Lowe VJ, Vemuri P, Mielke MM, Machulda MM, Jack CR, Petersen RC, Oz G, Kantarci K. (1)H MR spectroscopy biomarkers of neuronal and synaptic function are associated with tau deposition in cognitively unimpaired older adults. Neurobiol Aging. 2022 Apr; 112:16-26 Epub 2022 Jan 05
    View PubMed
  216. Vassilaki M, Aakre JA, Kremers WK, Mielke MM, Geda YE, Machulda MM, Knopman DS, Vemuri P, Lowe VJ, Jack CR Jr, Roberson ED, Gerstenecker A, Martin RC, Kennedy RE, Marson DC, Petersen RC. Association of Performance on the Financial Capacity Instrument-Short Form With Brain Amyloid Load and Cortical Thickness in Older Adults. Neurol Clin Pract. 2022 Apr; 12 (2):113-124
    View PubMed
  217. Choudhury P, Graff-Radford J, Aakre JA, Wurtz L, Knopman DS, Graff-Radford NR, Kantarci K, Forsberg LK, Fields JA, Pedraza O, Chen Q, Miyagawa T, Day GS, Tipton P, Savica R, Botha H, Lachner C, Dredla B, Reichard RR, Petersen RC, Dickson DW, Boeve BF, Ferman TJ. The temporal onset of the core features in dementia with Lewy bodies. Alzheimers Dement. 2022 Apr; 18 (4):591-601 Epub 2021 Nov 11
    View PubMed
  218. van Harten AC, Wiste HJ, Weigand SD, Mielke MM, Kremers WK, Eichenlaub U, Dyer RB, Algeciras-Schimnich A, Knopman DS, Jack CR Jr, Petersen RC. Detection of Alzheimer's disease amyloid beta 1-42, p-tau, and t-tau assays. Alzheimers Dement. 2022 Apr; 18 (4):635-644 Epub 2021 July 26
    View PubMed
  219. Mielke MM, Aakre JA, Algeciras-Schimnich A, Proctor NK, Machulda MM, Eichenlaub U, Knopman DS, Vemuri P, Graff-Radford J, Jack CR Jr, Petersen RC, Dage JL. Comparison of CSF phosphorylated tau 181 and 217 for cognitive decline. Alzheimers Dement. 2022 Apr; 18 (4):602-611 Epub 2021 July 26
    View PubMed
  220. Gomez GT, Gottesman RF, Gabriel KP, Palta P, Gross AL, Soldan A, Albert MS, Sullivan KJ, Jack CR Jr, Knopman DS, Windham BG, Walker KA. The association of motoric cognitive risk with incident dementia and neuroimaging characteristics: The Atherosclerosis Risk in Communities Study. Alzheimers Dement. 2022 Mar; 18 (3):434-444 Epub 2021 Nov 17
    View PubMed
  221. Koton S, Pike JR, Johansen M, Knopman DS, Lakshminarayan K, Mosley T, Patole S, Rosamond WD, Schneider ALC, Sharrett AR, Wruck L, Coresh J, Gottesman RF. Association of Ischemic Stroke Incidence, Severity, and Recurrence With Dementia in the Atherosclerosis Risk in Communities Cohort Study. JAMA Neurol. 2022 Mar 1; 79 (3):271-280
    View PubMed
  222. Ma XR, Prudencio M, Koike Y, Vatsavayai SC, Kim G, Harbinski F, Briner A, Rodriguez CM, Guo C, Akiyama T, Schmidt HB, Cummings BB, Wyatt DW, Kurylo K, Miller G, Mekhoubad S, Sallee N, Mekonnen G, Ganser L, Rubien JD, Jansen-West K, Cook CN, Pickles S, Oskarsson B, Graff-Radford NR, Boeve BF, Knopman DS, Petersen RC, Dickson DW, Shorter J, Myong S, Green EM, Seeley WW, Petrucelli L, Gitler AD. TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A. Nature. 2022 Mar; 603 (7899):124-130 Epub 2022 Feb 23
    View PubMed
  223. Jiayaspathi A, Chen LY, Selvin E, Gottesman RF, Knopman DS, Mosley TH, Norby FL, Alonso A. Relation of Diabetes Mellitus to Incident Dementia in Patients With Atrial Fibrillation (from the Atherosclerosis Risk in Communities Study). Am J Cardiol. 2022 Feb 15; 165:51-57 Epub 2021 Dec 06
    View PubMed
  224. Huo N, Vemuri P, Graff-Radford J, Syrjanen J, Machulda M, Knopman DS, Jack CR Jr, Petersen R, Mielke MM. Sex Differences in the Association Between Midlife Cardiovascular Conditions or Risk Factors With Midlife Cognitive Decline. Neurology. 2022 Feb 8; 98 (6):e623-e632 Epub 2022 Jan 05
    View PubMed
  225. Raghavan S, Przybelski SA, Reid RI, Lesnick TG, Ramanan VK, Botha H, Matchett BJ, Murray ME, Reichard RR, Knopman DS, Graff-Radford J, Jones DT, Lowe VJ, Mielke MM, Machulda MM, Petersen RC, Kantarci K, Whitwell JL, Josephs KA, Jack CR Jr, Vemuri P. White matter damage due to vascular, tau, and TDP-43 pathologies and its relevance to cognition. Acta Neuropathol Commun. 2022 Feb 5; 10 (1):16 Epub 2022 Feb 05
    View PubMed
  226. Graff-Radford J, Jones DT, Wiste HJ, Cogswell PM, Weigand SD, Lowe V, Elder BD, Vemuri P, Van Harten A, Mielke MM, Knopman DS, Graff-Radford NR, Petersen RC, Jack CR Jr, Gunter JL. Cerebrospinal fluid dynamics and discordant amyloid biomarkers. Neurobiol Aging. 2022 Feb; 110:27-36 Epub 2021 Nov 01
    View PubMed
  227. Ramanan VK, Heckman MG, Przybelski SA, Lesnick TG, Lowe VJ, Graff-Radford J, Mielke M, Jack CR, Knopman DS, Petersen RC, Ross OA, Vemuri P, Alzheimer's Disease Neuroimaging Initiative. Polygenic Scores of Alzheimer's Disease Risk Genes Add Only Modestly to APOE in Explaining Variation in Amyloid PET Burden. J Alzheimers Dis. 2022; 88 (4):1615-1625
    View PubMed
  228. Kamath V, Senjem ML, Spychalla AJ, Chen H, Palta P, Mosley TH, Windham BG, Griswold M, Knopman DS, Gottesman RF, Jack CR, Sharrett AR, Schneider ALC. The Neuroanatomic Correlates of Olfactory Identification Impairment in Healthy Older Adults and in Persons with Mild Cognitive Impairment. J Alzheimers Dis. 2022; 89 (1):233-245
    View PubMed
  229. Orlando A, Sharrett AR, Schneider ALC, Gottesman RF, Knopman DS, Rawlings A, Mosley TH, Jack CR, Wong D, Pike JR, Coresh J. Brain Imaging Features Associated with 20-Year Cognitive Decline in a Community-Based Multiethnic Cohort without Dementia. Neuroepidemiology. 2022; 56 (3):183-191 Epub 2022 May 02
    View PubMed
  230. Alden EC, Lundt ES, Twohy EL, Christianson TJ, Kremers WK, Machulda MM, Jack CR Jr, Knopman DS, Mielke MM, Petersen RC, Stricker NH. Mayo normative studies: A conditional normative model for longitudinal change on the Auditory Verbal Learning Test and preliminary validation in preclinical Alzheimer's disease. Alzheimers Dement (Amst). 2022; 14 (1):e12325 Epub 2022 July 15
    View PubMed
  231. Lucien F, Benarroch EE, Mullan A, Ali F, Boeve BF, Mielke MM, Petersen RC, Kim Y, Stang C, Camerucci E, Ross OA, Wszolek ZK, Knopman D, Bower J, Singer W, Savica R. Poly (ADP-Ribose) and alpha-synuclein extracellular vesicles in patients with Parkinson disease: A possible biomarker of disease severity. PLoS One. 2022; 17 (4):e0264446 Epub 2022 Apr 08
    View PubMed
  232. McCarter SJ, Lesnick TG, Lowe VJ, Rabinstein AA, Przybelski SA, Algeciras-Schimnich A, Ramanan VK, Jack CR, Petersen RC, Knopman DS, Boeve BF, Kantarci K, Vemuri P, Mielke MM, Graff-Radford J. Association Between Plasma Biomarkers of Amyloid, Tau, and Neurodegeneration with Cerebral Microbleeds. J Alzheimers Dis. 2022; 87 (4):1537-1547
    View PubMed
  233. Murray AM, Slinin Y, Tupper DE, Pederson SL, Davey C, Gilbertson DT, Drawz P, Mello R, Hart A, Johansen KL, Reule S, Rossom R, Knopman DS. Kidney-Metabolic Factors Associated with Cognitive Impairment in Chronic Kidney Disease: A Pilot Study. Am J Nephrol. 2022; 53 (6):435-445 Epub 2022 Apr 28
    View PubMed
  234. Kantarci K, Nedelska Z, Chen Q, Senjem ML, Schwarz CG, Gunter JL, Przybelski SA, Lesnick TG, Kremers WK, Fields JA, Graff-Radford J, Savica R, Jones D, Botha H, Knopman DS, Lowe V, Graff-Radford NR, Murray MM, Dickson DW, Reichard RR, Jack CR Jr, Petersen RC, Ferman TJ, Boeve BF. Longitudinal atrophy in prodromal dementia with Lewy bodies points to cholinergic degeneration. Brain Commun. 2022; 4(2):fcac013. Epub 2022 Feb 07.
    View PubMed
  235. Shen X, Raghavan S, Przybelski SA, Lesnick TG, Ma S, Reid RI, Graff-Radford J, Mielke MM, Knopman DS, Petersen RC, Jack CR Jr, Simon GJ, Vemuri P. Causal structure discovery identifies risk factors and early brain markers related to evolution of white matter hyperintensities. Neuroimage Clin. 2022; 35:103077 Epub 2022 June 07
    View PubMed
  236. Bretzman JP, Tseng AS, Graff-Radford J, Lee HC, Asirvatham SJ, Mielke MM, Knopman DS, Petersen RC, Jack CR Jr, Vemuri P, Rabinstein AA, DeSimone CV. Silent cerebral infarcts in patients with atrial fibrillation: Clinical implications of an imaging-adjusted CHA2DS2-VASc score. Cardiol J. 2022; 29 (5):766-772 Epub 2022 June 15
    View PubMed
  237. Schwarz CG, Knopman DS, Ramanan VK, Lowe VJ, Wiste HJ, Cogswell PM, Utianski RL, Senjem ML, Gunter JR, Vemuri P, Petersen RC, Jack CR. Longitudinally Increasing Elevated Asymmetric Flortaucipir Binding in a Cognitively Unimpaired Amyloid-Negative Older Individual. J Alzheimers Dis 2022; 85 (1):59-64
    View PubMed
  238. Windham BG, Parker SB, Zhu X, Gabriel KP, Palta P, Sullivan KJ, Parker KG, Knopman DS, Gottesman RF, Griswold ME, Mosley TH Jr. Endurance and gait speed relationships with mild cognitive impairment and dementia. Alzheimers Dement (Amst). 2022; 14 (1):e12281 Epub 2022 Feb 09
    View PubMed
  239. Jack CR Jr, Therneau TM, Lundt ES, Wiste HJ, Mielke MM, Knopman DS, Graff-Radford J, Lowe VJ, Vemuri P, Schwarz CG, Senjem ML, Gunter JL, Petersen RC. Long-term associations between amyloid positron emission tomography, sex, apolipoprotein E and incident dementia and mortality among individuals without dementia: hazard ratios and absolute risk. Brain Commun. 2022; 4 (2):fcac017 Epub 2022 Feb 02
    View PubMed
  240. Buciuc M, Martin PR, Tosakulwong N, Murray ME, Petrucelli L, Senjem ML, Spychalla AJ, Knopman DS, Boeve BF, Petersen RC, Parisi JE, Reichard RR, Dickson DW, Jack CR Jr, Whitwell JL, Josephs KA. TDP-43-associated atrophy in brains with and without frontotemporal lobar degeneration. Neuroimage Clin. 2022; 34:102954 Epub 2022 Feb 04
    View PubMed
  241. Shir D, Graff-Radford J, Hofrenning EI, Lesnick TG, Przybelski SA, Lowe VJ, Knopman DS, Petersen RC, Jack CR Jr, Vemuri P, Algeciras-Schimnich A, Campbell MR, Stricker NH, Mielke MM. Association of plasma glial fibrillary acidic protein (GFAP) with neuroimaging of Alzheimer's disease and vascular pathology. Alzheimers Dement (Amst). 2022; 14 (1):e12291 Epub 2022 Feb 28
    View PubMed
  242. Frenzel S, Bis JC, Gudmundsson EF, O'Donnell A, Simino J, Yaqub A, Bartz TM, Brusselle GGO, Bulow R, DeCarli CS, Ewert R, Gharib SA, Ghosh S, Gireud-Goss M, Gottesman RF, Ikram MA, Knopman DS, Launer LJ, London SJ, Longstreth WT, Lopez OL, Melo van Lent D, O'Connor G, Satizabal CL, Shrestha S, Sigurdsson S, Stubbe B, Talluri R, Vasan RS, Vernooij MW, Volzke H, Wiggins KL, Yu B, Beiser AS, Gudnason V, Mosley T, Psaty BM, Wolters FJ, Grabe HJ, Seshadri S. Associations of Pulmonary Function with MRI Brain Volumes: A Coordinated Multi-Study Analysis. J Alzheimers Dis. 2022; 90 (3):1073-1083
    View PubMed
  243. Butts AM, Machulda MM, Martin P, Przybelski SA, Duffy JR, Graff-Radford J, Knopman DS, Petersen RC, Jack CR Jr, Lowe VJ, Josephs KA, Whitwell JL. Temporal Cortical Thickness and Cognitive Associations among Typical and Atypical Phenotypes of Alzheimer's Disease. J Alzheimers Dis Rep. 2022; 6 (1):479-491 Epub 2022 Aug 05
    View PubMed
  244. Lachner C, Day GS, Camsari GB, Kouri N, Ertekin-Taner N, Boeve BF, Labuzan SA, Lucas JA, Thompson EA, Siddiqui H, Crook JE, Cabrera-Rodriguez JN, Josephs KA, Petersen RC, Dickson DW, Reichard RR, Mielke MM, Knopman DS, Graff-Radford NR, Murray ME. Cancer and Vascular Comorbidity Effects on Dementia Risk and Neuropathology in the Oldest-Old. J Alzheimers Dis. 2022; 90 (1):405-417
    View PubMed
  245. Lima M, Tabuas-Pereira M, Duraes J, Faustino P, Simoes MR, Kukull W, Knopman DS, Santana I. Portuguese version of the CDR plus NACC FTLD: Validation studies. Alzheimers Dement (Amst). 2022; 14 (1):e12355 Epub 2022 Nov 30
    View PubMed
  246. Singh NA, Arani A, Graff-Radford J, Senjem ML, Martin PR, Machulda MM, Schwarz CG, Shu Y, Cogswell PM, Knopman DS, Petersen RC, Lowe VJ, Jack CR Jr, Josephs KA, Whitwell JL. Distinct brain iron profiles associated with logopenic progressive aphasia and posterior cortical atrophy. Neuroimage Clin. 2022; 36:103161. Epub 2022 Aug 22.
    View PubMed
  247. Marks JD, Syrjanen JA, Graff-Radford J, Petersen RC, Machulda MM, Campbell MR, Algeciras-Schimnich A, Lowe V, Knopman DS, Jack CR Jr, Vemuri P, Mielke MM, Alzheimer's Disease Neuroimaging Initiative. Comparison of plasma neurofilament light and total tau as neurodegeneration markers: associations with cognitive and neuroimaging outcomes. Alzheimers Res Ther. 2021 Dec 14; 13 (1):199
    View PubMed
  248. Fields JA, Forsberg LK, Knutson M, Seifert SJ, Farah-Milller EA, Melius JL, Miller JK, Knopman DS, Boeve BF, Petersen RC, Kramer KM, Lunde AM. Assessing the needs of Black/African American dementia caregivers seeking emotional support. Alzheimers Dement. 2021 Dec; 17 Suppl 8:e056579
    View PubMed
  249. Krell-Roesch J, Syrjanen JA, Rakusa M, Vemuri P, Machulda MM, Kremers WK, Mielke MM, Lowe VJ, Jack CR Jr, Knopman DS, Stokin GB, Petersen RC, Vassilaki M, Geda YE. Association of Cortical and Subcortical beta-Amyloid With Standardized Measures of Depressive and Anxiety Symptoms in Adults Without Dementia. J Neuropsychiatry Clin Neurosci. 2021 Winter; 33 (1):64-71 Epub 2020 Oct 22
    View PubMed
  250. Schumacher J, Gunter JL, Przybelski SA, Jones DT, Graff-Radford J, Savica R, Schwarz CG, Senjem ML, Jack CR, Lowe VJ, Knopman DS, Fields JA, Kremers WK, Petersen RC, Graff-Radford NR, Ferman TJ, Boeve BF, Thomas AJ, Taylor JP, Kantarci K. Dementia with Lewy bodies: association of Alzheimer pathology with functional connectivity networks. Brain. 2021 Nov 29; 144 (10):3212-3225
    View PubMed
  251. Therneau TM, Knopman DS, Lowe VJ, Botha H, Graff-Radford J, Jones DT, Vemuri P, Mielke MM, Schwarz CG, Senjem ML, Gunter JL, Petersen RC, Jack CR Jr. Relationships between beta-amyloid and tau in an elderly population: An accelerated failure time model. Neuroimage. 2021 Nov 15; 242:118440 Epub 2021 July 29
    View PubMed
  252. McCarter SJ, Lesnick TG, Lowe V, Mielke MM, Constantopoulos E, Rabinstein AA, Przybelski SA, Botha H, Jones DT, Ramanan VK, Jack CR, Petersen RC, Knopman D, Boeve BF, Murray ME, Dickson DW, Vemuri P, Kantarci K, Reichard RR, Graff-Radford J. Cerebral Amyloid Angiopathy Pathology and Its Association With Amyloid-beta PET Signal. Neurology. 2021 Nov 2; 97 (18):e1799-e1808 Epub 2021 Sept 09
    View PubMed
  253. Damotte V, van der Lee SJ, Chouraki V, Grenier-Boley B, Simino J, Adams H, Tosto G, White C, Terzikhan N, Cruchaga C, Knol MJ, Li S, Schraen S, Grove ML, Satizabal C, Amin N, Berr C, Younkin S, Gottesman RF, Buee L, Beiser A, Knopman DS, Uitterlinden A, DeCarli C, Bressler J, DeStefano A, Dartigues JF, Yang Q, Boerwinkle E, Tzourio C, Fornage M, Ikram MA, Amouyel P, de Jager P, Reitz C, Mosley TH, Lambert JC, Seshadri S, van Duijn CM, Alzheimer's Disease Neuroimaging Initiative. Plasma amyloid beta levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants. Alzheimers Dement. 2021 Oct; 17 (10):1663-1674 Epub 2021 May 18
    View PubMed
  254. Liu CC, Murray ME, Li X, Zhao N, Wang N, Heckman MG, Shue F, Martens Y, Li Y, Raulin AC, Rosenberg CL, Doss SV, Zhao J, Wren MC, Jia L, Ren Y, Ikezu TC, Lu W, Fu Y, Caulfield T, Trottier ZA, Knight J, Chen Y, Linares C, Wang X, Kurti A, Asmann YW, Wszolek ZK, Smith GE, Vemuri P, Kantarci K, Knopman DS, Lowe VJ, Jack CR Jr, Parisi JE, Ferman TJ, Boeve BF, Graff-Radford NR, Petersen RC, Younkin SG, Fryer JD, Wang H, Han X, Frieden C, Dickson DW, Ross OA, Bu G. APOE3-Jacksonville (V236E) variant reduces self-aggregation and risk of dementia. Sci Transl Med. 2021 Sep 29; 13(613):eabc9375.
    View PubMed
  255. Sullivan KJ, Blackshear C, Simino J, Tin A, Walker KA, Sharrett AR, Younkin S, Gottesman RF, Mielke MM, Knopman D, Windham BG, Griswold ME, Mosley TH. Association of Midlife Plasma Amyloid-beta Levels With Cognitive Impairment in Late Life: The ARIC Neurocognitive Study. Neurology. 2021 Sep 14; 97 (11):e1123-e1131 Epub 2021 Aug 04
    View PubMed
  256. Knopman DS, Perlmutter JS. Prescribing Aducanumab in the Face of Meager Efficacy and Real Risks. Neurology 2021 Sep 14; 97 (11):545-547 Epub 2021 July 07
    View PubMed
  257. Sprung J, Laporta M, Knopman DS, Petersen RC, Mielke MM, Weingarten TN, Vassilaki M, Martin DP, Schulte PJ, Hanson AC, Schroeder DR, Vemuri P, Warner DO. Gait Speed and Instrumental Activities of Daily Living in Older Adults After Hospitalization: A Longitudinal Population-Based Study. J Gerontol A Biol Sci Med Sci. 2021 Sep 13; 76 (10):e272-e280
    View PubMed
  258. Walker KA, Silverstein N, Zhou Y, Hughes TM, Jack CR Jr, Knopman DS, Sharrett AR, Wong DF, Mosley TH, Gottesman RF. Brain White Matter Structure and Amyloid Deposition in Black and White Older Adults: The ARIC-PET Study. J Am Heart Assoc. 2021 Sep 7; 10 (17):e022087 Epub 2021 Aug 25
    View PubMed
  259. Knopman DS. Young-Onset Dementia-New Insights for an Underappreciated Problem. JAMA Neurol 2021 Sep 1; 78 (9):1055-1056
    View PubMed
  260. Mielke MM, Frank RD, Dage JL, Jeromin A, Ashton NJ, Blennow K, Karikari TK, Vanmechelen E, Zetterberg H, Algeciras-Schimnich A, Knopman DS, Lowe V, Bu G, Vemuri P, Graff-Radford J, Jack CR Jr, Petersen RC. Comparison of Plasma Phosphorylated Tau Species With Amyloid and Tau Positron Emission Tomography, Neurodegeneration, Vascular Pathology, and Cognitive Outcomes. JAMA Neurol. 2021 Sep 1; 78 (9):1108-1117
    View PubMed
  261. Schwarz CG, Therneau TM, Weigand SD, Gunter JL, Lowe VJ, Przybelski SA, Senjem ML, Botha H, Vemuri P, Kantarci K, Boeve BF, Whitwell JL, Josephs KA, Petersen RC, Knopman DS, Jack CR Jr. Selecting software pipelines for change in flortaucipir SUVR: Balancing repeatability and group separation. Neuroimage. 2021 Sep; 238:118259 Epub 2021 June 09
    View PubMed
  262. Ferreira D, Nedelska Z, Graff-Radford J, Przybelski SA, Lesnick TG, Schwarz CG, Botha H, Senjem ML, Fields JA, Knopman DS, Savica R, Ferman TJ, Graff-Radford NR, Lowe VJ, Jack CR, Petersen RC, Lemstra AW, van de Beek M, Barkhof F, Blanc F, Loureiro de Sousa P, Philippi N, Cretin B, Demuynck C, Hort J, Oppedal K, Boeve BF, Aarsland D, Westman E, Kantarci K. Cerebrovascular disease, neurodegeneration, and clinical phenotype in dementia with Lewy bodies. Neurobiol Aging. 2021 Sep; 105:252-261 Epub 2021 May 14
    View PubMed
  263. Chen Q, Boeve BF, Forghanian-Arani A, Senjem ML, Jack CR Jr, Przybelski SA, Lesnick TG, Kremers WK, Fields JA, Schwarz CG, Gunter JL, Trzasko JD, Graff-Radford J, Savica R, Knopman DS, Dickson DW, Ferman TJ, Graff-Radford N, Petersen RC, Kantarci K. MRI quantitative susceptibility mapping of the substantia nigra as an early biomarker for Lewy body disease. J Neuroimaging. 2021 Sep; 31 (5):1020-1027 Epub 2021 May 25
    View PubMed
  264. Krell-Roesch J, Syrjanen JA, Machulda MM, Christianson TJ, Kremers WK, Mielke MM, Knopman DS, Petersen RC, Vassilaki M, Geda YE. Neuropsychiatric symptoms and the outcome of cognitive trajectories in older adults free of dementia: The Mayo Clinic Study of Aging. Int J Geriatr Psychiatry. 2021 Sep; 36 (9):1362-1369 Epub 2021 Mar 24
    View PubMed
  265. Alexander GC, Knopman DS, Emerson SS, Ovbiagele B, Kryscio RJ, Perlmutter JS, Kesselheim AS. Revisiting FDA Approval of Aducanumab. N Engl J Med. 2021 Aug 26; 385 (9):769-771 Epub 2021 July 28
    View PubMed
  266. Graff-Radford J, Lesnick T, Rabinstein AA, Gunter JL, Przybelski SA, Noseworthy PA, Preboske GM, Mielke MM, Lowe VJ, Knopman DS, Petersen RC, Kremers WK, Jack CR Jr, Vemuri P, Kantarci K. Cerebral Microbleeds: Relationship to Antithrombotic Medications. Stroke. 2021 Jul; 52 (7):2347-2355 Epub 2021 May 10
    View PubMed
  267. Petersen RC, Wiste HJ, Weigand SD, Fields JA, Geda YE, Graff-Radford J, Knopman DS, Kremers WK, Lowe V, Machulda MM, Mielke MM, Stricker NH, Therneau TM, Vemuri P, Jack CR Jr. NIA-AA Alzheimer's Disease Framework: Clinical Characterization of Stages. Ann Neurol. 2021 Jun; 89 (6):1145-1156 Epub 2021 Apr 06
    View PubMed
  268. Cogswell PM, Weigand SD, Wiste HJ, Gunter JL, Graff-Radford J, Jones DT, Schwarz CG, Senjem ML, Knopman DS, Petersen RC, Jack CR Jr. CSF dynamics as a predictor of cognitive progression. Neuroimage. 2021 May 15; 232:117899 Epub 2021 Feb 23
    View PubMed
  269. Knopman DS, Amieva H, Petersen RC, Chetelat G, Holtzman DM, Hyman BT, Nixon RA, Jones DT. Alzheimer disease. Nat Rev Dis Primers. 2021 May 13; 7 (1):33
    View PubMed
  270. DeJesus-Hernandez M, Aleff RA, Jackson JL, Finch NA, Baker MC, Gendron TF, Murray ME, McLaughlin IJ, Harting JR, Graff-Radford NR, Oskarsson B, Knopman DS, Josephs KA, Boeve BF, Petersen RC, Fryer JD, Petrucelli L, Dickson DW, Rademakers R, Ebbert MTW, Wieben ED, van Blitterswijk M. Long-read targeted sequencing uncovers clinicopathological associations for C9orf72-linked diseases. Brain. 2021 May 7; 144 (4):1082-1088
    View PubMed
  271. Rojas JC, Wang P, Staffaroni AM, Heller C, Cobigo Y, Wolf A, Goh SM, Ljubenkov PA, Heuer HW, Fong JC, Taylor JB, Veras E, Song L, Jeromin A, Hanlon D, Yu L, Khinikar A, Sivasankaran R, Kieloch A, Valentin MA, Karydas AM, Mitic LL, Pearlman R, Kornak J, Kramer JH, Miller BL, Kantarci K, Knopman DS, Graff-Radford N, Petrucelli L, Rademakers R, Irwin DJ, Grossman M, Ramos EM, Coppola G, Mendez MF, Bordelon Y, Dickerson BC, Ghoshal N, Huey ED, Mackenzie IR, Appleby BS, Domoto-Reilly K, Hsiung GR, Toga AW, Weintraub S, Kaufer DI, Kerwin D, Litvan I, Onyike CU, Pantelyat A, Roberson ED, Tartaglia MC, Foroud T, Chen W, Czerkowicz J, Graham DL, van Swieten JC, Borroni B, Sanchez-Valle R, Moreno F, Laforce R, Graff C, Synofzik M, Galimberti D, Rowe JB, Masellis M, Finger E, Vandenberghe R, de Mendonca A, Tagliavini F, Santana I, Ducharme S, Butler CR, Gerhard A, Levin J, Danek A, Otto M, Sorbi S, Cash DM, Convery RS, Bocchetta M, Foiani M, Greaves CV, Peakman G, Russell L, Swift I, Todd E, Rohrer JD, Boeve BF, Rosen HJ, Boxer AL, ALLFTD and GENFI consortia. Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration. Neurology. 2021 May 4; 96 (18):e2296-e2312 Epub 2021 Apr 07
    View PubMed
  272. Mielke MM, Przybelski SA, Lesnick TG, Kern S, Zetterberg H, Blennow K, Knopman DS, Graff-Radford J, Petersen RC, Jack CR Jr, Vemuri P. Comparison of CSF neurofilament light chain, neurogranin, and tau to MRI markers. Alzheimers Dement. 2021 May; 17 (5):801-812 Epub 2021 Mar 04
    View PubMed
  273. Schwarz CG, Kremers WK, Wiste HJ, Gunter JL, Vemuri P, Spychalla AJ, Kantarci K, Schultz AP, Sperling RA, Knopman DS, Petersen RC, Jack CR Jr, Alzheimer's Disease Neuroimaging Initiative. Changing the face of neuroimaging research: Comparing a new MRI de-facing technique with popular alternatives. Neuroimage. 2021 May 1; 231:117845 Epub 2021 Feb 11
    View PubMed
  274. Alden EC, Pudumjee SB, Lundt ES, Albertson SM, Machulda MM, Kremers WK, Jack CR Jr, Knopman DS, Petersen RC, Mielke MM, Stricker NH. Diagnostic accuracy of the Cogstate Brief Battery for prevalent MCI and prodromal AD (MCI A(+) T(+) ) in a population-based sample. Alzheimers Dement. 2021 Apr; 17 (4):584-594 Epub 2021 Mar 01
    View PubMed
  275. Knopman DS, Jones DT, Greicius MD. Failure to demonstrate efficacy of aducanumab: An analysis of the EMERGE and ENGAGE trials as reported by Biogen, December 2019. Alzheimers Dement. 2021 Apr; 17 (4):696-701 Epub 2020 Nov 01
    View PubMed
  276. Sprung J, Warner DO, Knopman DS, Petersen RC, Mielke MM, Jack CR Jr, Martin DP, Hanson AC, Schroeder DR, Przybelski SA, Schulte PJ, Laporta ML, Weingarten TN, Vemuri P. Brain MRI after critical care admission: A longitudinal imaging study. J Crit Care. 2021 Apr; 62:117-123 Epub 2020 Dec 05
    View PubMed
  277. Ramanan VK, Lesnick TG, Przybelski SA, Heckman MG, Knopman DS, Graff-Radford J, Lowe VJ, Machulda MM, Mielke MM, Jack CR Jr, Petersen RC, Ross OA, Vemuri P, Alzheimer's Disease Neuroimaging Initiative (ADNI). Coping with brain amyloid: genetic heterogeneity and cognitive resilience to Alzheimer's pathophysiology. Acta Neuropathol Commun. 2021 Mar 23; 9 (1):48
    View PubMed
  278. Miyagawa T, Przybelski SA, Maltais D, Min HK, Jordan L, Lesnick TG, Chen Q, Graff-Radford J, Jones D, Savica R, Knopman D, Petersen R, Kremers WK, Forsberg LK, Fields JA, Ferman TJ, Allen L, Parisi J, Reichard RR, Murray M, Dickson D, Boeve BF, Kantarci K, Lowe VJ. The value of multimodal imaging with (123)I-FP-CIT SPECT in differential diagnosis of dementia with Lewy bodies and Alzheimer's disease dementia. Neurobiol Aging. 2021 Mar; 99:11-18 Epub 2020 Dec 15
    View PubMed
  279. Sprung J, Knopman DS, Petersen RC, Mielke MM, Weingarten TN, Vassilaki M, Martin DP, Schulte PJ, Hanson AC, Schroeder DR, Laporta ML, White RJ, Vemuri P, Warner DO. Association of Hospitalization with Long-Term Cognitive Trajectories in Older Adults. J Am Geriatr Soc. 2021 Mar; 69 (3):660-668 Epub 2020 Oct 31
    View PubMed
  280. Stricker NH, Christianson TJ, Lundt ES, Alden EC, Machulda MM, Fields JA, Kremers WK, Jack CR, Knopman DS, Mielke MM, Petersen RC. Mayo Normative Studies: Regression-Based Normative Data for the Auditory Verbal Learning Test for Ages 30-91 Years and the Importance of Adjusting for Sex. J Int Neuropsychol Soc. 2021 Mar; 27 (3):211-226 Epub 2020 Aug 20
    View PubMed
  281. Chen Q, Lowe VJ, Boeve BF, Przybelski SA, Miyagawa T, Senjem ML, Jack CR Jr, Lesnick TG, Kremers WK, Fields JA, Min HK, Schwarz CG, Gunter JL, Graff-Radford J, Savica R, Knopman DS, Jones D, Ferman TJ, Graff-Radford NR, Petersen RC, Kantarci K. Beta-amyloid pet and 123i-fp-cit spect in mild cognitive impairment at risk for Lewy body dementia Neurology. 2021 Feb 23; 96 (8):E1180-9
  282. Chen Q, Lowe VJ, Boeve BF, Przybelski SA, Miyagawa T, Senjem ML, Jack CR Jr, Lesnick TG, Kremers WK, Fields JA, Min HK, Schwarz CG, Gunter JL, Graff-Radford J, Savica R, Knopman DS, Jones D, Ferman TJ, Graff-Radford NR, Petersen RC, Kantarci K. beta-Amyloid PET and (123)I-FP-CIT SPECT in Mild Cognitive Impairment at Risk for Lewy Body Dementia. Neurology. 2021 Feb 22; 96 (8):e1180-e1189
    View PubMed
  283. Palta P, Sharrett AR, Gabriel KP, Gottesman RF, Folsom AR, Power MC, Evenson KR, Jack CR Jr, Knopman DS, Mosley TH, Heiss G. Prospective Analysis of Leisure-Time Physical Activity in Midlife and Beyond and Brain Damage on MRI in Older Adults. Neurology. 2021 Feb 16; 96 (7):e964-e974 Epub 2021 Jan 06
    View PubMed
  284. Krell-Roesch J, Syrjanen JA, Vassilaki M, Lowe VJ, Vemuri P, Mielke MM, Machulda MM, Stokin GB, Christianson TJ, Kremers WK, Jack CR Jr, Knopman DS, Petersen RC, Geda YE. Brain Regional Glucose Metabolism, Neuropsychiatric Symptoms, and the Risk of Incident Mild Cognitive Impairment: The Mayo Clinic Study of Aging. Am J Geriatr Psychiatry. 2021 Feb; 29 (2):179-191 Epub 2020 June 17
    View PubMed
  285. Knopman DS, Lundt ES, Therneau TM, Albertson SM, Gunter JL, Senjem ML, Schwarz CG, Mielke MM, Machulda MM, Boeve BF, Jones DT, Graff-Radford J, Vemuri P, Kantarci K, Lowe VJ, Petersen RC, Jack CR Jr, Alzheimer's Disease Neuroimaging Initiative. Association of Initial beta-Amyloid Levels With Subsequent Flortaucipir Positron Emission Tomography Changes in Persons Without Cognitive Impairment. JAMA Neurol. 2021 Feb 1; 78 (2):217-228
    View PubMed
  286. Giebel CM, Knopman D, Mioshi E, Khondoker M. Distinguishing Frontotemporal Dementia From Alzheimer Disease Through Everyday Function Profiles: Trajectories of Change. J Geriatr Psychiatry Neurol. 2021 Jan; 34 (1):66-75 Epub 2020 Feb 13
    View PubMed
  287. Machulda MM, Lundt ES, Mester CT, Albertson SM, Raghavan S, Reid RI, Schwarz CG, Graff-Radford J, Jack CR Jr, Knopman DS, Mielke MM, Kremers WK, Petersen RC, Bondi MW, Vemuri P. White matter changes in empirically derived incident MCI subtypes in the Mayo Clinic Study of Aging. Alzheimers Dement (Amst). 2021; 13 (1):e12269 Epub 2021 Dec 31
    View PubMed
  288. Townley RA, Botha H, Graff-Radford J, Whitwell J, Boeve BF, Machulda MM, Fields JA, Drubach DA, Savica R, Petersen RC, Senjem ML, Knopman DS, Lowe VJ, Jack CR Jr, Josephs KA, Jones DT. Posterior cortical atrophy phenotypic heterogeneity revealed by decoding (18)F-FDG-PET. Brain Commun. 2021; 3 (4):fcab182 Epub 2021 Aug 19
    View PubMed
  289. Powell DS, Kuo PL, Qureshi R, Coburn SB, Knopman DS, Palta P, Gottesman R, Griswold M, Albert M, Deal JA, Gross AL. The Relationship of APOE epsilon4, Race, and Sex on the Age of Onset and Risk of Dementia. Front Neurol. 2021; 12:735036 Epub 2021 Oct 20
    View PubMed
  290. Vemuri P, Davey C, Johansen KL, Zuk SM, Reid RI, Thostenson KB, Reddy AL, Jack CR, Knopman DS, Murray AM. Chronic Kidney Disease Associated with Worsening White Matter Disease and Ventricular Enlargement. J Alzheimers Dis. 2021; 83 (4):1729-1740
    View PubMed
  291. Najar J, Aakre JA, Vassilaki M, Wetterberg H, Ryden L, Zettergren A, Skoog I, Jack CR, Knopman DS, Petersen RC, Kern S, Mielke MM. Sex Difference in the Relation Between Marital Status and Dementia Risk in Two Population-Based Cohorts. J Alzheimers Dis. 2021; 83 (3):1269-1279
    View PubMed
  292. Kantarci K, Boeve BF, Przybelski SA, Lesnick TG, Chen Q, Fields J, Schwarz CG, Senjem ML, Gunte JL, Jack CR, Min P, Jain M, Miyagawa T, Savica R, Graff-Radford J, Botha H, Jones DT, Knopman DS, Graff-Radford N, Ferman TJ, Petersen RC, Lowe VJ. FDG PET metabolic signatures distinguishing prodromal DLB and prodromal AD. Neuroimage Clin. 2021; 31:102754 Epub 2021 July 04
    View PubMed
  293. Pudumjee SB, Lundt ES, Albertson SM, Machulda MM, Kremers WK, Jack CR, Knopman DS, Petersen RC, Mielke MM, Stricker NH. A Comparison of Cross-Sectional and Longitudinal Methods of Defining Objective Subtle Cognitive Decline in Preclinical Alzheimer's Disease Based on Cogstate One Card Learning Accuracy Performance. J Alzheimers Dis. 2021; 83 (2):861-877
    View PubMed
  294. Rentz DM, Wessels AM, Annapragada AV, Berger AK, Edgar CJ, Gold M, Miller DS, Randolph C, Ryan JM, Wunderlich G, Zoschg MC, Trepel D, Knopman DS, Staffaroni AM, Bain LJ, Carrillo MC, Weber CJ. Building clinically relevant outcomes across the Alzheimer's disease spectrum. Alzheimers Dement (N Y). 2021; 7 (1):e12181 Epub 2021 June 26
    View PubMed
  295. Raghavan S, Reid RI, Przybelski SA, Lesnick TG, Graff-Radford J, Schwarz CG, Knopman DS, Mielke MM, Machulda MM, Petersen RC, Jack CR Jr, Vemuri P. Diffusion models reveal white matter microstructural changes with ageing, pathology and cognition. Brain Commun. 2021; 3 (2):fcab106 Epub 2021 May 19
    View PubMed
  296. Graff-Radford J, Lesnick TG, Mielke MM, Constantopoulos E, Rabinstein AA, Przybelski SA, Vemuri P, Botha H, Jones DT, Ramanan VK, Petersen RC, Knopman DS, Boeve BF, Murray ME, Dickson DW, Jack CR, Kantarci K, Reichard RR. Cerebral Amyloid Angiopathy Burden and Cerebral Microbleeds: Pathological Evidence for Distinct Phenotypes. J Alzheimers Dis. 2021; 81 (1):113-122
    View PubMed
  297. Vemuri P, Graff-Radford J, Lesnick TG, Przybelski SA, Reid RI, Reddy AL, Lowe VJ, Mielke MM, Machulda MM, Petersen RC, Knopman DS, Jack CR Jr. White matter abnormalities are key components of cerebrovascular disease impacting cognitive decline. Brain Commun. 2021; 3 (2):fcab076 Epub 2021 Apr 12
    View PubMed
  298. Poulakis K, Reid RI, Przybelski SA, Knopman DS, Graff-Radford J, Lowe VJ, Mielke MM, Machulda MM, Jack CR Jr, Petersen RC, Westman E, Vemuri P. Longitudinal deterioration of white-matter integrity: heterogeneity in the ageing population. Brain Commun. 2021; 3 (1):fcaa238 Epub 2021 Jan 22
    View PubMed
  299. Raghavan S, Graff-Radford J, Scharf E, Przybelski SA, Lesnick TG, Gregg B, Schwarz CG, Gunter JL, Zuk SM, Rabinstein A, Mielke MM, Petersen RC, Knopman DS, Kantarci K, Jack CR Jr, Vemuri P. Study of Symptomatic vs. Silent Brain Infarctions on MRI in Elderly Subjects. Front Neurol. 2021; 12:615024 Epub 2021 Feb 17
    View PubMed
  300. Buciuc M, Tosakulwong N, Machulda MM, Whitwell JL, Weigand SD, Murray ME, Reichard RR, Parisi JE, Dickson DW, Boeve BF, Knopman DS, Petersen RC, Josephs KA. TAR DNA-Binding Protein 43 Is Associated with Rate of Memory, Functional and Global Cognitive Decline in the Decade Prior to Death. J Alzheimers Dis. 2021; 80 (2):683-693
    View PubMed
  301. Krell-Roesch J, Syrjanen JA, Bezold J, Trautwein S, Barisch-Fritz B, Boes K, Woll A, Forzani E, Kremers WK, Machulda MM, Mielke MM, Knopman DS, Petersen RC, Vassilaki M, Geda YE. Physical Activity and Trajectory of Cognitive Change in Older Persons: Mayo Clinic Study of Aging. J Alzheimers Dis. 2021; 79 (1):377-388
    View PubMed
  302. Chu SA, Flagan TM, Staffaroni AM, Jiskoot LC, Deng J, Spina S, Zhang L, Sturm VE, Yokoyama JS, Seeley WW, Papma JM, Geschwind DH, Rosen HJ, Boeve BF, Boxer AL, Heuer HW, Forsberg LK, Brushaber DE, Grossman M, Coppola G, Dickerson BC, Bordelon YM, Faber K, Feldman HH, Fields JA, Fong JC, Foroud T, Gavrilova RH, Ghoshal N, Graff-Radford NR, Hsiung GR, Huey ED, Irwin DJ, Kantarci K, Kaufer DI, Karydas AM, Knopman DS, Kornak J, Kramer JH, Kukull WA, Lapid MI, Litvan I, Mackenzie IRA, Mendez MF, Miller BL, Onyike CU, Pantelyat AY, Rademakers R, Marisa Ramos E, Roberson ED, Carmela Tartaglia M, Tatton NA, Toga AW, Vetor A, Weintraub S, Wong B, Wszolek ZK, Van Swieten JC, Lee SE, ARTFL/LEFFTDS Consortium. Brain volumetric deficits in MAPT mutation carriers: a multisite study. Ann Clin Transl Neurol. 2021 Jan; 8 (1):95-110 Epub 2020 Nov 28
    View PubMed
  303. Cogswell PM, Wiste HJ, Senjem ML, Gunter JL, Weigand SD, Schwarz CG, Arani A, Therneau TM, Lowe VJ, Knopman DS, Botha H, Graff-Radford J, Jones DT, Kantarci K, Vemuri P, Boeve BF, Mielke MM, Petersen RC, Jack CR Jr. Associations of quantitative susceptibility mapping with Alzheimer's disease clinical and imaging markers. Neuroimage. 2021 Jan 1; 224:117433 Epub 2020 Oct 06
    View PubMed
  304. Ferreira D, Przybelski SA, Lesnick TG, Lemstra AW, Londos E, Blanc F, Nedelska Z, Schwarz CG, Graff-Radford J, Senjem ML, Fields JA, Knopman DS, Savica R, Ferman TJ, Graff-Radford NR, Lowe VJ, Jack CR Jr, Petersen RC, Mollenhauer B, Garcia-Ptacek S, Abdelnour C, Hort J, Bonanni L, Oppedal K, Kramberger MG, Boeve BF, Aarsland D, Westman E, Kantarci K. beta-Amyloid and tau biomarkers and clinical phenotype in dementia with Lewy bodies. Neurology. 2020 Dec 15; 95 (24):e3257-e3268 Epub 2020 Sept 28
    View PubMed
  305. Whitwell JL, Tosakulwong N, Schwarz CC, Senjem ML, Spychalla AJ, Duffy JR, Graff-Radford J, Machulda MM, Boeve BF, Knopman DS, Petersen RC, Lowe VJ, Jack CR Jr, Dickson DW, Parisi JE, Josephs KA. Longitudinal anatomic, functional, and molecular characterization of Pick disease phenotypes. Neurology. 2020 Dec 15; 95(24):e3190-e3202. Epub 2020 Sep 28.
    View PubMed
  306. Johansen MC, Mosley TH, Knopman DS, Wong DF, Ndumele C, Shah AM, Solomon SD, Gottesman RF. Associations Between Atrial Cardiopathy and Cerebral Amyloid: The ARIC-PET Study. J Am Heart Assoc. 2020 Dec 15; 9 (24):e018399 Epub 2020 Dec 08
    View PubMed
  307. Johnson EL, Krauss GL, Kucharska-Newton A, Albert MS, Brandt J, Walker KA, Yasar S, Knopman DS, Vossel KA, Gottesman RF. Dementia in late-onset epilepsy: The Atherosclerosis Risk in Communities study. Neurology. 2020 Dec 15; 95 (24):e3248-e3256 Epub 2020 Oct 23
    View PubMed
  308. Sargurupremraj M, Suzuki H, Jian X, Sarnowski C, Evans TE, Bis JC, Eiriksdottir G, Sakaue S, Terzikhan N, Habes M, Zhao W, Armstrong NJ, Hofer E, Yanek LR, Hagenaars SP, Kumar RB, van den Akker EB, McWhirter RE, Trompet S, Mishra A, Saba Y, Satizabal CL, Beaudet G, Petit L, Tsuchida A, Zago L, Schilling S, Sigurdsson S, Gottesman RF, Lewis CE, Aggarwal NT, Lopez OL, Smith JA, Valdes Hernandez MC, van der Grond J, Wright MJ, Knol MJ, Dorr M, Thomson RJ, Bordes C, Le Grand Q, Duperron MG, Smith AV, Knopman DS, Schreiner PJ, Evans DA, Rotter JI, Beiser AS, Maniega SM, Beekman M, Trollor J, Stott DJ, Vernooij MW, Wittfeld K, Niessen WJ, Soumare A, Boerwinkle E, Sidney S, Turner ST, Davies G, Thalamuthu A, Volker U, van Buchem MA, Bryan RN, Dupuis J, Bastin ME, Ames D, Teumer A, Amouyel P, Kwok JB, Bulow R, Deary IJ, Schofield PR, Brodaty H, Jiang J, Tabara Y, Setoh K, Miyamoto S, Yoshida K, Nagata M, Kamatani Y, Matsuda F, Psaty BM, Bennett DA, De Jager PL, Mosley TH, Sachdev PS, Schmidt R, Warren HR, Evangelou E, Tregouet DA, Ikram MA, Wen W, DeCarli C, Srikanth VK, Jukema JW, Slagboom EP, Kardia SLR, Okada Y, Mazoyer B, Wardlaw JM, Nyquist PA, Mather KA, Grabe HJ, Schmidt H, Van Duijn CM, Gudnason V, Longstreth WT Jr, Launer LJ, Lathrop M, Seshadri S, Tzourio C, Adams HH, Matthews PM, Fornage M, Debette S, International Network against Thrombosis (INVENT) Consortium//International Headache Genomics Consortium (IHGC). Cerebral small vessel disease genomics and its implications across the lifespan. Nat Commun. 2020 Dec 8; 11 (1):6285 Epub 2020 Dec 08
    View PubMed
  309. Josephs KA, Martin PR, Weigand SD, Tosakulwong N, Buciuc M, Murray ME, Petrucelli L, Senjem ML, Spychalla AJ, Knopman DS, Boeve BF, Petersen RC, Parisi JE, Dickson DW, Jack CR, Whitwell JL. Protein contributions to brain atrophy acceleration in Alzheimer's disease and primary age-related tauopathy. Brain. 2020 Dec 5; 143 (11):3463-3476
    View PubMed
  310. Scheppach JB, Coresh J, Wu A, Gottesman RF, Mosley TH, Knopman DS, Grams ME, Sharrett AR, Koton S. Albuminuria and Estimated GFR as Risk Factors for Dementia in Midlife and Older Age: Findings From the ARIC Study. Am J Kidney Dis. 2020 Dec; 76 (6):775-783 Epub 2020 May 16
    View PubMed
  311. Raghavan S, Przybelski SA, Reid RI, Graff-Radford J, Lesnick TG, Zuk SM, Knopman DS, Machulda MM, Mielke MM, Petersen RC, Jack CR Jr, Vemuri P. Reduced fractional anisotropy of the genu of the corpus callosum as a cerebrovascular disease marker and predictor of longitudinal cognition in MCI. Neurobiol Aging. 2020 Dec; 96:176-183 Epub 2020 Sept 08
    View PubMed
  312. Christopoulos G, Graff-Radford J, Lopez CL, Yao X, Attia ZI, Rabinstein AA, Petersen RC, Knopman DS, Mielke MM, Kremers W, Vemuri P, Siontis KC, Friedman PA, Noseworthy PA. Artificial Intelligence-Electrocardiography to Predict Incident Atrial Fibrillation: A Population-Based Study. Circ Arrhythm Electrophysiol. 2020 Dec; 13 (12):e009355 Epub 2020 Nov 13
    View PubMed
  313. Moazzami K, Power MC, Gottesman R, Mosley T, Lutsey PL, Jack CR Jr, Hoogeveen RC, West N, Knopman DS, Alonso A. Association of mid-life serum lipid levels with late-life brain volumes: The atherosclerosis risk in communities neurocognitive study (ARICNCS). Neuroimage. 2020 Dec; 223:117324 Epub 2020 Sept 01
    View PubMed
  314. Hodis JD, Gottesman RF, Windham BG, Knopman DS, Lutsey PL, Walker KA, Alonso A. Association of Hypertension According to New American College of Cardiology/American Heart Association Blood Pressure Guidelines With Incident Dementia in the ARIC Study Cohort. J Am Heart Assoc. 2020 Nov 17; 9 (22):e017546 Epub 2020 Nov 10
    View PubMed
  315. Prudencio M, Humphrey J, Pickles S, Brown AL, Hill SE, Kachergus JM, Shi J, Heckman MG, Spiegel MR, Cook C, Song Y, Yue M, Daughrity LM, Carlomagno Y, Jansen-West K, de Castro CF, DeTure M, Koga S, Wang YC, Sivakumar P, Bodo C, Candalija A, Talbot K, Selvaraj BT, Burr K, Chandran S, Newcombe J, Lashley T, Hubbard I, Catalano D, Kim D, Propp N, Fennessey S, Fagegaltier D, Phatnani H, Secrier M, Fisher EM, Oskarsson B, van Blitterswijk M, Rademakers R, Graff-Radford NR, Boeve BF, Knopman DS, Petersen RC, Josephs KA, Thompson EA, Raj T, Ward M, Dickson DW, Gendron TF, Fratta P, Petrucelli L, NYGC ALS Consortium. Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia. J Clin Invest. 2020 Nov 2; 130 (11):6080-6092
    View PubMed
  316. Caselli RJ, Knopman DS, Bu G. An agnostic reevaluation of the amyloid cascade hypothesis of Alzheimer's disease pathogenesis: The role of APP homeostasis. Alzheimers Dement. 2020 Nov; 16 (11):1582-1590 Epub 2020 June 26
    View PubMed
  317. Ighodaro ET, Graff-Radford J, Syrjanen JA, Bui HH, Petersen RC, Knopman DS, Jack CR Jr, Zuk SM, Vemuri P, Mielke MM. Associations Between Plasma Ceramides and Cerebral Microbleeds or Lacunes. Arterioscler Thromb Vasc Biol. 2020 Nov; 40 (11):2785-2793 Epub 2020 Sept 03
    View PubMed
  318. Jack CR, Wiste HJ, Weigand SD, Therneau TM, Lowe VJ, Knopman DS, Botha H, Graff-Radford J, Jones DT, Ferman TJ, Boeve BF, Kantarci K, Vemuri P, Mielke MM, Whitwell J, Josephs K, Schwarz CG, Senjem ML, Gunter JL, Petersen RC. Predicting future rates of tau accumulation on PET. Brain. 2020 Oct 1; 143 (10):3136-3150
    View PubMed
  319. Staffaroni AM, Goh SM, Cobigo Y, Ong E, Lee SE, Casaletto KB, Wolf A, Forsberg LK, Ghoshal N, Graff-Radford NR, Grossman M, Heuer HW, Hsiung GR, Kantarci K, Knopman DS, Kremers WK, Mackenzie IR, Miller BL, Pedraza O, Rascovsky K, Tartaglia MC, Wszolek ZK, Kramer JH, Kornak J, Boeve BF, Boxer AL, Rosen HJ, ARTFL-LEFFTDS Longitudinal Frontotemporal Lobar Degeneration Consortium. Rates of Brain Atrophy Across Disease Stages in Familial Frontotemporal Dementia Associated With MAPT, GRN, and C9orf72 Pathogenic Variants. JAMA Netw Open. 2020 Oct 1; 3 (10):e2022847 Epub 2020 Oct 01
    View PubMed
  320. Choudhury P, Scharf EL, Paolini MA 2nd, Graff-Radford J, Alden EC, Machulda MM, Jones DT, Fields JA, Murray ME, Graff-Radford NR, Constantopoulos E, Reichard RR, Knopman DS, Duffy JR, Dickson DW, Parisi JE, Josephs KA, Petersen RC, Boeve BF. Pick's disease: clinicopathologic characterization of 21 cases. J Neurol. 2020 Sep; 267 (9):2697-2704 Epub 2020 May 21
    View PubMed
  321. Li D, Hagen C, Bui HH, Knopman D, Jack CR, Machulda M, Petersen RC, Mielke MM. Associations between cerebrospinal fluid total phosphatidylcholines, neurodegeneration, cognitive decline, and risk of mild cognitive impairment in the Mayo Clinic Study of Aging. Neurobiol Aging. 2020 Sep; 93:52-54 Epub 2020 Apr 28
    View PubMed
  322. Utianski RL, Botha H, Whitwell JL, Martin PR, Schwarz CG, Duffy JR, Clark HM, Spychalla AJ, Senjem ML, Petersen RC, Knopman DS, Jack CR Jr, Lowe VJ, Josephs KA. Longitudinal flortaucipir ([(18)F]AV-1451) PET uptake in semantic dementia. Neurobiol Aging. 2020 Aug; 92:135-140 Epub 2020 Apr 18
    View PubMed
  323. Gentry MT, Lapid MI, Syrjanen J, Calvert K, Hughes S, Brushaber D, Kremers W, Bove J, Brannelly P, Coppola G, Dheel C, Dickerson B, Dickinson S, Faber K, Fields J, Fong J, Foroud T, Forsberg L, Gavrilova R, Gearhart D, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grossman M, Haley D, Heuer H, Hsiung GY, Huey E, Irwin D, Jones D, Jones L, Kantarci K, Karydas A, Knopman D, Kornak J, Kramer J, Kukull W, Lucente D, Lungu C, Mackenzie I, Manoochehri M, McGinnis S, Miller B, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin K, Rascovsky K, Sengdy P, Shaw L, Tatton N, Taylor J, Toga A, Trojanowski J, Weintraub S, Wong B, Wszolek Z, Boeve BF, Boxer A, Rosen H, LEFFTDS Consortium. Quality of life and caregiver burden in familial frontotemporal lobar degeneration: Analyses of symptomatic and asymptomatic individuals within the LEFFTDS cohort. Alzheimers Dement. 2020 Aug; 16 (8):1115-1124 Epub 2020 July 13
    View PubMed
  324. Buciuc M, Whitwell JL, Tosakulwong N, Weigand SD, Murray ME, Boeve BF, Knopman DS, Parisi JE, Petersen RC, Dickson DW, Josephs KA. Association between transactive response DNA-binding protein of 43 kDa type and cognitive resilience to Alzheimer's disease: a case-control study. Neurobiol Aging. 2020 Aug; 92:92-97 Epub 2020 Apr 15
    View PubMed
  325. Sprung J, Abcejo ASA, Knopman DS, Petersen RC, Mielke MM, Hanson AC, Schroeder DR, Schulte PJ, Martin DP, Weingarten TN, Pasternak JJ, Warner DO. Anesthesia With and Without Nitrous Oxide and Long-term Cognitive Trajectories in Older Adults. Anesth Analg. 2020 Aug; 131 (2):594-604
    View PubMed
  326. Van Harten AC, Wiste HJ, Weigand SD, Mielke MM, Kremers WK, Eichenlaub U, Batrla-Utermann R, Dyer RB, Algeciras-Schimnich A, Knopman DS, Jack CR Jr, Petersen RC. CSF biomarkers in Olmsted County: Evidence of 2 subclasses and associations with demographics. Neurology. 2020 Jul 21; 95 (3):e256-e267 Epub 2020 June 26
    View PubMed
  327. Bejanin A, Tammewar G, Marx G, Cobigo Y, Iaccarino L, Kornak J, Staffaroni AM, Dickerson BC, Boeve BF, Knopman DS, Gorno-Tempini M, Miller BL, Jagust WJ, Boxer AL, Rosen HJ, Rabinovici GD. Longitudinal structural and metabolic changes in frontotemporal dementia. Neurology. 2020 Jul 14; 95 (2):e140-e154 Epub 2020 June 26
    View PubMed
  328. Ferman TJ, Aoki N, Boeve BF, Aakre JA, Kantarci K, Graff-Radford J, Parisi JE, Van Gerpen JA, Graff-Radford NR, Uitti RJ, Pedraza O, Murray ME, Wszolek ZK, Reichard RR, Fields JA, Ross OA, Knopman DS, Petersen RC, Dickson DW. Subtypes of dementia with Lewy bodies are associated with alpha-synuclein and tau distribution. Neurology. 2020 Jul 14; 95 (2):e155-e165 Epub 2020 June 19
    View PubMed
  329. Buciuc M, Botha H, Murray ME, Schwarz CG, Senjem ML, Jones DT, Knopman DS, Boeve BF, Petersen RC, Jack CR Jr, Petrucelli L, Parisi JE, Dickson DW, Lowe V, Whitwell JL, Josephs KA. Utility of FDG-PET in diagnosis of Alzheimer-related TDP-43 proteinopathy. Neurology. 2020 Jul 7; 95 (1):e23-e34 Epub 2020 June 09
    View PubMed
  330. Machulda MM, Lundt ES, Albertson SM, Spychalla AJ, Schwarz CG, Mielke MM, Jack CR Jr, Kremers WK, Vemuri P, Knopman DS, Jones DT, Bondi MW, Petersen RC. Cortical atrophy patterns of incident MCI subtypes in the Mayo Clinic Study of Aging. Alzheimers Dement. 2020 Jul; 16 (7):1013-1022 Epub 2020 May 17
    View PubMed
  331. Knopman D, Lemere CA, Lamb BT, Craft S, Gitlin LN, Golde TE, Pericak-Vance M, Sano M, Schellenberg G, Schneider JA, Zheng H, Khachaturian Z, Snyder HM, Carrillo MC. Scientific Advising and Reviewing: On strengthening the bond between the Alzheimer's Association and the scientific community. Alzheimers Dement. 2020 Jul; 16 (7):1095-1098 Epub 2020 May 19
    View PubMed
  332. Sintini I, Graff-Radford J, Senjem ML, Schwarz CG, Machulda MM, Martin PR, Jones DT, Boeve BF, Knopman DS, Kantarci K, Petersen RC, Jack CR, Lowe VJ, Josephs KA, Whitwell JL. Longitudinal neuroimaging biomarkers differ across Alzheimer's disease phenotypes. Brain. 2020 Jul 1; 143 (7):2281-2294
    View PubMed
  333. Knopman DS. The Enigma of Decreasing Dementia Incidence. JAMA Netw Open 2020 Jul 1; 3 (7):e2011199 Epub 2020 July 01
    View PubMed
  334. Toller G, Ranasinghe K, Cobigo Y, Staffaroni A, Appleby B, Brushaber D, Coppola G, Dickerson B, Domoto-Reilly K, Fields J, Fong J, Forsberg L, Ghoshal N, Graff-Radford N, Grossman M, Heuer H, Hsiung GY, Huey E, Irwin D, Kantarci K, Kaufer D, Kerwin D, Knopman D, Kornak J, Kramer J, Litvan I, Mackenzie I, Mendez M, Miller B, Rademakers R, Ramos E, Rascovsky K, Roberson E, Syrjanen J, Tartaglia C, Weintraub S, Boeve B, Boxer A, Rosen H, Rankin K, ARTFL/LEFFTDS Consortium. Revised Self-Monitoring Scale: A potential endpoint for frontotemporal dementia clinical trials. Neurology. 2020 Jun 2; 94 (22):e2384-e2395 Epub 2020 May 05
    View PubMed
  335. Walker KA, Gottesman RF, Coresh J, Sharrett AR, Knopman DS, Mosley TH Jr, Alonso A, Zhou Y, Wong DF, Brown CH 4th. Association of Surgical Hospitalization with Brain Amyloid Deposition: The Atherosclerosis Risk in Communities-Positron Emission Tomography (ARIC-PET) Study. Anesthesiology. 2020 Jun; 132 (6):1407-1418
    View PubMed
  336. Graff-Radford J, Aakre JA, Knopman DS, Schwarz CG, Flemming KD, Rabinstein AA, Gunter JL, Ward CP, Zuk SM, Spychalla AJ, Preboske GM, Petersen RC, Kantarci K, Huston J 3rd, Jack CR Jr, Mielke MM, Vemuri P. Prevalence and Heterogeneity of Cerebrovascular Disease Imaging Lesions. Mayo Clin Proc. 2020 Jun; 95 (6):1195-1205
    View PubMed
  337. Kruthiventi SC, Laporta ML, Deljou A, Knopman DS, Petersen RC, Schroeder DR, Sprung J, Weingarten TN. Preoperative cognitive impairment associated with oversedation during recovery from anesthesia. J Anesth. 2020 Jun; 34 (3):390-396 Epub 2020 Mar 28
    View PubMed
  338. Li D, Misialek JR, Jing M, Tsai MY, Eckfeldt JH, Steffen LM, Knopman D, Wruck L, Gottesman R, Mosley TH, Sharrett AR, Alonso A. Plasma phospholipid very-long-chain SFAs in midlife and 20-year cognitive change in the Atherosclerosis Risk in Communities (ARIC): a cohort study. Am J Clin Nutr. 2020 Jun 1; 111 (6):1252-1258
    View PubMed
  339. Vassilaki M, Syrjanen JA, Kremers WK, Hagen PT, Knopman DS, Mielke MM, Geda YE, Alhurani RE, Machulda MM, Roberts RO, Petersen RC. Medical Doctors and Dementia: A Longitudinal Study. J Am Geriatr Soc. 2020 Jun; 68 (6):1250-1255 Epub 2020 Feb 22
    View PubMed
  340. Liu P, Smith BR, Montonye ML, Kemper LJ, Leinonen-Wright K, Nelson KM, Higgins L, Guerrero CR, Markowski TW, Zhao X, Petersen AJ, Knopman DS, Petersen RC, Ashe KH. Author Correction: A soluble truncated tau species related to cognitive dysfunction is elevated in the brain of cognitively impaired human individuals. Sci Rep. 2020 May 12; 10 (1):8077
    View PubMed
  341. Sprung J, Warner DO, Knopman DS, Petersen RC, Mielke MM, Jack CR Jr, Lowe VJ, Martin DP, Hanson AC, Schroeder DR, Przybelski SA, Schulte PJ, Weingarten TN, Vemuri P. Exposure to surgery with general anaesthesia during adult life is not associated with increased brain amyloid deposition in older adults. Br J Anaesth. 2020 May; 124 (5):594-602 Epub 2020 Mar 12
    View PubMed
  342. Josephs KA, Tosakulwong N, Graff-Radford J, Weigand SD, Buciuc M, Machulda MM, Jones DT, Schwarz CG, Senjem ML, Ertekin-Taner N, Kantarci K, Boeve BF, Knopman DS, Jack CR Jr, Petersen RC, Lowe VJ, Whitwell JL. MRI and flortaucipir relationships in Alzheimer's phenotypes are heterogeneous. Ann Clin Transl Neurol. 2020 May; 7 (5):707-721 Epub 2020 Apr 15
    View PubMed
  343. Buciuc M, Whitwell JL, Boeve BF, Ferman TJ, Graff-Radford J, Savica R, Kantarci K, Fields JA, Knopman DS, Petersen RC, Parisi JE, Murray ME, Dickson DW, Josephs KA. TDP-43 is associated with a reduced likelihood of rendering a clinical diagnosis of dementia with Lewy bodies in autopsy-confirmed cases of transitional/diffuse Lewy body disease. J Neurol. 2020 May; 267 (5):1444-1453 Epub 2020 Jan 31
    View PubMed
  344. van der Lee SJ, Conway OJ, Jansen I, Carrasquillo MM, Kleineidam L, van den Akker E, Hernandez I, van Eijk KR, Stringa N, Chen JA, Zettergren A, Andlauer TFM, Diez-Fairen M, Simon-Sanchez J, Lleo A, Zetterberg H, Nygaard M, Blauwendraat C, Savage JE, Mengel-From J, Moreno-Grau S, Wagner M, Fortea J, Keogh MJ, Blennow K, Skoog I, Friese MA, Pletnikova O, Zulaica M, Lage C, de Rojas I, Riedel-Heller S, Illan-Gala I, Wei W, Jeune B, Orellana A, Then Bergh F, Wang X, Hulsman M, Beker N, Tesi N, Morris CM, Indakoetxea B, Collij LE, Scherer M, Morenas-Rodriguez E, Ironside JW, van Berckel BNM, Alcolea D, Wiendl H, Strickland SL, Pastor P, Rodriguez Rodriguez E, Boeve BF, Petersen RC, Ferman TJ, van Gerpen JA, Reinders MJT, Uitti RJ, Tarraga L, Maier W, Dols-Icardo O, Kawalia A, Dalmasso MC, Boada M, Zettl UK, van Schoor NM, Beekman M, Allen M, Masliah E, de Munain AL, Pantelyat A, Wszolek ZK, Ross OA, Dickson DW, Graff-Radford NR, Knopman D, Rademakers R, Lemstra AW, Pijnenburg YAL, Scheltens P, Gasser T, Chinnery PF, Hemmer B, Huisman MA, Troncoso J, Moreno F, Nohr EA, Sorensen TIA, Heutink P, Sanchez-Juan P, Posthuma D, Clarimon J, Christensen K, Ertekin-Taner N, Scholz SW, Ramirez A, Ruiz A, Slagboom E, van der Flier WM, Holstege H, DESGESCO (Dementia Genetics Spanish Consortium)//EADB (Alzheimer Disease European DNA biobank)//IFGC (International FTD-Genomics Consortium)//IPDGC (The International Parkinson Disease Genomics Consortium)//RiMod-FTD (Risk and Modifying factors in Fronto-Temporal Dementia)//Netherlands Brain Bank . Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity. Acta Neuropathol. 2020 May; 139 (5):959-962
    View PubMed
  345. Carvalho DZ, St Louis EK, Schwarz CG, Lowe VJ, Boeve BF, Przybelski SA, Reddy A, Mielke MM, Knopman DS, Petersen RC, Jack CR Jr, Vemuri P. Witnessed apneas are associated with elevated tau-PET levels in cognitively unimpaired elderly. Neurology. 2020 Apr 28; 94 (17):e1793-e1802 Epub 2020 Mar 26
    View PubMed
  346. Arenaza-Urquijo EM, Przybelski SA, Machulda MM, Knopman DS, Lowe VJ, Mielke MM, Reddy AL, Geda YE, Jack CR Jr, Petersen RC, Vemuri P. Better stress coping associated with lower tau in amyloid-positive cognitively unimpaired older adults. Neurology. 2020 Apr 14; 94 (15):e1571-e1579 Epub 2020 Jan 21
    View PubMed
  347. Vassilaki M, Aakre JA, Kremers WK, Lesnick TG, Mielke MM, Geda YE, Machulda MM, Knopman DS, Butler L, Traber M, Vemuri P, Lowe VJ, Jack CR Jr, Roberts RO, Petersen RC. Brain amyloid, cortical thickness, and changes in activities of daily living. Ann Clin Transl Neurol. 2020 Apr; 7 (4):474-485 Epub 2020 Apr 21
    View PubMed
  348. Chen Q, Boeve BF, Senjem M, Tosakulwong N, Lesnick T, Brushaber D, Dheel C, Fields J, Forsberg L, Gavrilova R, Gearhart D, Graff-Radford J, Graff-Radford N, Jack CR Jr, Jones D, Knopman D, Kremers WK, Lapid M, Rademakers R, Ramos EM, Syrjanen J, Boxer AL, Rosen H, Wszolek ZK, Kantarci K. Trajectory of lobar atrophy in asymptomatic and symptomatic GRN mutation carriers: a longitudinal MRI study. Neurobiol Aging. 2020 Apr; 88:42-50 Epub 2019 Dec 12
    View PubMed
  349. Zeydan B, Lowe VJ, Reichard RR, Przybelski SA, Lesnick TG, Schwarz CG, Senjem ML, Gunter JL, Parisi JE, Machulda MM, Vemuri P, Mielke MM, Knopman DS, Petersen RC, Jack CR Jr, Kantarci OH, Kantarci K. Imaging Biomarkers of Alzheimer Disease in Multiple Sclerosis. Ann Neurol. 2020 Apr; 87 (4):556-567 Epub 2020 Feb 08
    View PubMed
  350. Ghisays V, Goradia DD, Protas H, Bauer RJ 3rd, Devadas V, Tariot PN, Lowe VJ, Knopman DS, Petersen RC, Jack CR Jr, Caselli RJ, Su Y, Chen K, Reiman EM. Brain imaging measurements of fibrillar amyloid-beta burden, paired helical filament tau burden, and atrophy in cognitively unimpaired persons with two, one, and no copies of the APOE epsilon4 allele. Alzheimers Dement. 2020 Apr; 16 (4):598-609 Epub 2020 Jan 16
    View PubMed
  351. Liu P, Smith BR, Montonye ML, Kemper LJ, Leinonen-Wright K, Nelson KM, Higgins L, Guerrero CR, Markowski TW, Zhao X, Petersen AJ, Knopman DS, Petersen RC, Ashe KH. A soluble truncated tau species related to cognitive dysfunction is elevated in the brain of cognitively impaired human individuals. Sci Rep. 2020 Mar 2; 10 (1):3869 Epub 2020 Mar 02
    View PubMed
  352. Gottesman RF, Mosley TH, Knopman DS, Hao Q, Wong D, Wagenknecht LE, Hughes TM, Qiao Y, Dearborn J, Wasserman BA. Association of Intracranial Atherosclerotic Disease With Brain beta-Amyloid Deposition: Secondary Analysis of the ARIC Study. JAMA Neurol. 2020 Mar 1; 77 (3):350-357
    View PubMed
  353. Turcano P, Stang CD, Mielke MM, Martin PR, Upadhyaya SG, Josephs KA, Boeve BF, Knopman DS, Petersen RC, Savica R. Incidence of frontotemporal disorders in Olmsted County: A population-based study. Alzheimers Dement. 2020 Mar; 16 (3):482-490 Epub 2020 Jan 04
    View PubMed
  354. Lowe VJ, Lundt ES, Albertson SM, Min HK, Fang P, Przybelski SA, Senjem ML, Schwarz CG, Kantarci K, Boeve B, Jones DT, Reichard RR, Tranovich JF, Hanna Al-Shaikh FS, Knopman DS, Jack CR Jr, Dickson DW, Petersen RC, Murray ME. Tau-positron emission tomography correlates with neuropathology findings. Alzheimers Dement. 2020 Mar; 16 (3):561-571 Epub 2020 Jan 04
    View PubMed
  355. Utianski RL, Martin PR, Botha H, Schwarz CG, Duffy JR, Petersen RC, Knopman DS, Clark HM, Butts AM, Machulda MM, Jack CR Jr, Lowe VJ, Whitwell JL, Josephs KA. Longitudinal flortaucipir ([(18)F]AV-1451) PET imaging in primary progressive apraxia of speech. Cortex. 2020 Mar; 124:33-43 Epub 2019 Nov 19
    View PubMed
  356. Crook JE, Gunter JL, Ball CT, Jones DT, Graff-Radford J, Knopman DS, Boeve BF, Petersen RC, Jack CR, Graff-Radford NR. Linear vs volume measures of ventricle size: Relation to present and future gait and cognition. Neurology. 2020 Feb 4; 94 (5):e549-e556 Epub 2019 Nov 20
    View PubMed
  357. Moore KM, Nicholas J, Grossman M, McMillan CT, Irwin DJ, Massimo L, Van Deerlin VM, Warren JD, Fox NC, Rossor MN, Mead S, Bocchetta M, Boeve BF, Knopman DS, Graff-Radford NR, Forsberg LK, Rademakers R, Wszolek ZK, van Swieten JC, Jiskoot LC, Meeter LH, Dopper EG, Papma JM, Snowden JS, Saxon J, Jones M, Pickering-Brown S, Le Ber I, Camuzat A, Brice A, Caroppo P, Ghidoni R, Pievani M, Benussi L, Binetti G, Dickerson BC, Lucente D, Krivensky S, Graff C, Oijerstedt L, Fallstrom M, Thonberg H, Ghoshal N, Morris JC, Borroni B, Benussi A, Padovani A, Galimberti D, Scarpini E, Fumagalli GG, Mackenzie IR, Hsiung GR, Sengdy P, Boxer AL, Rosen H, Taylor JB, Synofzik M, Wilke C, Sulzer P, Hodges JR, Halliday G, Kwok J, Sanchez-Valle R, Llado A, Borrego-Ecija S, Santana I, Almeida MR, Tabuas-Pereira M, Moreno F, Barandiaran M, Indakoetxea B, Levin J, Danek A, Rowe JB, Cope TE, Otto M, Anderl-Straub S, de Mendonca A, Maruta C, Masellis M, Black SE, Couratier P, Lautrette G, Huey ED, Sorbi S, Nacmias B, Laforce R Jr, Tremblay ML, Vandenberghe R, Damme PV, Rogalski EJ, Weintraub S, Gerhard A, Onyike CU, Ducharme S, Papageorgiou SG, Ng ASL, Brodtmann A, Finger E, Guerreiro R, Bras J, Rohrer JD, FTD Prevention Initiative. Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study. Lancet Neurol. 2020 Feb; 19 (2):145-156 Epub 2019 Dec 03
    View PubMed
  358. Kantarci K, Lowe VJ, Chen Q, Przybelski SA, Lesnick TG, Schwarz CG, Senjem ML, Gunter JL, Jack CR Jr, Graff-Radford J, Jones DT, Knopman DS, Graff-Radford N, Ferman TJ, Parisi JE, Dickson DW, Petersen RC, Boeve BF, Murray ME. beta-Amyloid PET and neuropathology in dementia with Lewy bodies. Neurology. 2020 Jan 21; 94 (3):e282-e291 Epub 2019 Dec 20
    View PubMed
  359. Graff-Radford J, Lesnick T, Rabinstein AA, Gunter J, Aakre J, Przybelski SA, Spychalla AJ, Huston J 3rd, Brown RD Jr, Mielke MM, Lowe VJ, Knopman DS, Petersen RC, Jack CR Jr, Vemuri P, Kremers W, Kantarci K. Cerebral microbleed incidence, relationship to amyloid burden: The Mayo Clinic Study of Aging. Neurology. 2020 Jan 14; 94 (2):e190-e199 Epub 2019 Dec 04
    View PubMed
  360. Staffaroni AM, Cobigo Y, Goh SM, Kornak J, Bajorek L, Chiang K, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dever R, Dheel C, Dickerson BC, Dickinson S, Dominguez S, Domoto-Reilly K, Faber K, Ferrall J, Fields JA, Fishman A, Fong J, Foroud T, Forsberg LK, Gavrilova R, Gearhart D, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant I, Grossman M, Haley D, Heuer HW, Hsiung GY, Huey ED, Irwin DJ, Jones DT, Jones L, Kantarci K, Karydas A, Kaufer DI, Kerwin DR, Knopman DS, Kraft R, Kramer JH, Kremers WK, Kukull WA, Litvan I, Ljubenkov PA, Lucente D, Lungu C, Mackenzie IR, Maldonado M, Manoochehri M, McGinnis SM, McKinley E, Mendez MF, Miller BL, Multani N, Onyike C, Padmanabhan J, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin KP, Rascovsky K, Roberson ED, Rogalski E, Sengdy P, Shaw LM, Syrjanen J, Tartaglia MC, Tatton N, Taylor J, Toga A, Trojanowski JQ, Weintraub S, Wang P, Wong B, Wszolek Z, Boxer AL, Boeve BF, Rosen HJ, ARTFL/LEFFTDS consortium. Individualized atrophy scores predict dementia onset in familial frontotemporal lobar degeneration. Alzheimers Dement. 2020 Jan; 16 (1):37-48 Epub 2020 Jan 06
    View PubMed
  361. Sonsin-Diaz N, Gottesman RF, Fracica E, Walston J, Windham BG, Knopman DS, Walker KA. Chronic Systemic Inflammation Is Associated With Symptoms of Late-Life Depression: The ARIC Study. Am J Geriatr Psychiatry. 2020 Jan; 28 (1):87-98 Epub 2019 May 21
    View PubMed
  362. Palta P, Heiss G, Sharrett AR, Gabriel KP, Walker K, Evenson KR, Knopman D, Mosley TH, Wong DF, Gottesman RF. Mid- and Late-Life Leisure-Time Physical Activity and Global Brain Amyloid Burden: The Atherosclerosis Risk in Communities (ARIC)-PET Study. J Alzheimers Dis. 2020; 76 (1):139-147
    View PubMed
  363. Graff-Radford J, Lesnick TG, Savica R, Chen Q, Ferman TJ, Przybelski SA, Jones DT, Senjem ML, Gunter JL, Kremers WK, Jack CR Jr, Lowe VJ, Petersen RC, Knopman DS, Boeve BF, Murray ME, Dickson DW, Kantarci K. (18)F-fluorodeoxyglucose positron emission tomography in dementia with Lewy bodies. Brain Commun. 2020; 2 (1):fcaa040 Epub 2020 Apr 08
    View PubMed
  364. Townley RA, Graff-Radford J, Mantyh WG, Botha H, Polsinelli AJ, Przybelski SA, Machulda MM, Makhlouf AT, Senjem ML, Murray ME, Reichard RR, Savica R, Boeve BF, Drubach DA, Josephs KA, Knopman DS, Lowe VJ, Jack CR Jr, Petersen RC, Jones DT. Progressive dysexecutive syndrome due to Alzheimer's disease: a description of 55 cases and comparison to other phenotypes. Brain Commun. 2020; 2 (1):fcaa068 Epub 2020 May 27
    View PubMed
  365. Stricker NH, Lundt ES, Albertson SM, Machulda MM, Pudumjee SB, Kremers WK, Jack CR, Knopman DS, Petersen RC, Mielke MM. Diagnostic and Prognostic Accuracy of the Cogstate Brief Battery and Auditory Verbal Learning Test in Preclinical Alzheimer's Disease and Incident Mild Cognitive Impairment: Implications for Defining Subtle Objective Cognitive Impairment. J Alzheimers Dis. 2020; 76 (1):261-274
    View PubMed
  366. Sprung J, Knopman DS, Petersen RC, Vemuri P, Mielke MM, Weingarten TN, Schulte PJ, Schroeder DR, Warner DO. Exposure to surgery with regional anesthesia and cortical thickness in older adults. Alzheimers Dement (N Y). 2020; 6 (1):e12012 Epub 2020 Apr 07
    View PubMed
  367. Stricker NH, Lundt ES, Alden EC, Albertson SM, Machulda MM, Kremers WK, Knopman DS, Petersen RC, Mielke MM. Longitudinal Comparison of in Clinic and at Home Administration of the Cogstate Brief Battery and Demonstrated Practice Effects in the Mayo Clinic Study of Aging. J Prev Alzheimers Dis. 2020; 7 (1):21-28
    View PubMed
  368. Ramos EM, Dokuru DR, Van Berlo V, Wojta K, Wang Q, Huang AY, Deverasetty S, Qin Y, van Blitterswijk M, Jackson J, Appleby B, Bordelon Y, Brannelly P, Brushaber DE, Dickerson B, Dickinson S, Domoto-Reilly K, Faber K, Fields J, Fong J, Foroud T, Forsberg LK, Gavrilova R, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant I, Grossman M, Heuer HW, Hsiung GR, Huey E, Irwin D, Kantarci K, Karydas A, Kaufer D, Kerwin D, Knopman D, Kornak J, Kramer JH, Kremers W, Kukull W, Litvan I, Ljubenkov P, Lungu C, Mackenzie I, Mendez MF, Miller BL, Onyike C, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rankin KP, Rascovsky K, Roberson ED, Rogalski E, Shaw L, Syrjanen J, Tartaglia MC, Tatton N, Taylor J, Toga A, Trojanowski JQ, Weintraub S, Wong B, Wszolek Z, Rademakers R, Boeve BF, Rosen HJ, Boxer AL, Coppola G, ARTFL/LEFFTDS consortium. Genetic screening of a large series of North American sporadic and familial frontotemporal dementia cases. Alzheimers Dement. 2020 Jan; 16 (1):118-130
    View PubMed
  369. Miyagawa T, Brushaber D, Syrjanen J, Kremers W, Fields J, Forsberg LK, Heuer HW, Knopman D, Kornak J, Boxer A, Rosen HJ, Boeve BF, Appleby B, Bordelon Y, Bove J, Brannelly P, Caso C, Coppola G, Dever R, Dheel C, Dickerson B, Dickinson S, Dominguez S, Domoto-Reilly K, Faber K, Ferrell J, Fishman A, Fong J, Foroud T, Gavrilova R, Gearhart D, Ghazanfari B, Ghoshal N, Goldman JS, Graff-Radford J, Graff-Radford N, Grant I, Grossman M, Haley D, Hsiung R, Huey E, Irwin D, Jones D, Jones L, Kantarci K, Karydas A, Kaufer D, Kerwin D, Kraft R, Kramer J, Kukull W, Litvan I, Lucente D, Lungu C, Mackenzie I, Maldonado M, Manoochehri M, McGinnis S, McKinley E, Mendez MF, Miller B, Multani N, Onyike C, Padmanabhan J, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin K, Rascovsky K, Roberson ED, Rogalski E, Sengdy P, Shaw L, Tartaglia MC, Tatton N, Taylor J, Toga A, Trojanowski JQ, Wang P, Weintraub S, Wong B, Wszolek Z. Utility of the global CDR((R)) plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium. Alzheimers Dement. 2020 Jan; 16 (1):106-117
    View PubMed
  370. Staffaroni AM, Bajorek L, Casaletto KB, Cobigo Y, Goh SM, Wolf A, Heuer HW, Elahi FM, Ljubenkov PA, Dever R, Kornak J, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dheel C, Dickerson BC, Dickinson S, Dominguez S, Domoto-Reilly K, Faber K, Ferrall J, Fields JA, Fishman A, Fong J, Foroud T, Forsberg LK, Gavrilova R, Gearhart D, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant I, Grossman M, Haley D, Hsiung GY, Huey ED, Irwin DJ, Jones DT, Jones L, Kantarci K, Karydas A, Kaufer DI, Kerwin DR, Knopman DS, Kraft R, Kremers WK, Kukull WA, Litvan I, Lucente D, Lungu C, Mackenzie IR, Maldonado M, Manoochehri M, McGinnis SM, McKinley E, Mendez MF, Miller BL, Multani N, Onyike C, Padmanabhan J, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin KP, Rascovsky K, Roberson ED, Rogalski E, Sengdy P, Shaw LM, Syrjanen J, Tartaglia MC, Tatton N, Taylor J, Toga A, Trojanowski JQ, Weintraub S, Wang P, Wong B, Wszolek Z, Boxer AL, Boeve BF, Kramer JH, Rosen HJ, ARTFL/LEFFTDS consortium. Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint. Alzheimers Dement. 2020 Jan; 16 (1):11-21
    View PubMed
  371. Buciuc M, Wennberg AM, Weigand SD, Murray ME, Senjem ML, Spychalla AJ, Boeve BF, Knopman DS, Jack CR, Kantarci K, Parisi JE, Dickson DW, Petersen RC, Whitwell JL, Josephs KA. Effect Modifiers of TDP-43-Associated Hippocampal Atrophy Rates in Patients with Alzheimer's Disease Neuropathological Changes. J Alzheimers Dis. 2020; 73 (4):1511-1523
    View PubMed
  372. Olney NT, Ong E, Goh SM, Bajorek L, Dever R, Staffaroni AM, Cobigo Y, Bock M, Chiang K, Ljubenkov P, Kornak J, Heuer HW, Wang P, Rascovsky K, Wolf A, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dickerson BC, Dickinson S, Domoto-Reilly K, Faber K, Ferrall J, Fields J, Fishman A, Fong J, Foroud T, Forsberg LK, Gearhart DJ, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford NR, Grant I, Grossman M, Haley D, Hsiung G, Huey ED, Irwin DJ, Jones DT, Kantarci K, Karydas AM, Kaufer D, Kerwin D, Knopman DS, Kramer JH, Kraft R, Kremers W, Kukull W, Lapid MI, Litvan I, Mackenzie IR, Maldonado M, Manoochehri M, McGinnis SM, McKinley EC, Mendez MF, Miller BL, Onyike C, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin KP, Roberson ED, Rogalski E, Sengdy P, Shaw LM, Syrjanen J, Tartaglia MC, Tatton N, Taylor J, Toga A, Trojanowski JQ, Weintraub S, Wong B, Wszolek Z, Boxer AL, Boeve BF, Rosen HJ, ARTFL and LEFFTDS consortia. Clinical and volumetric changes with increasing functional impairment in familial frontotemporal lobar degeneration. Alzheimers Dement. 2020 Jan; 16 (1):49-59 Epub 2020 Jan 06
    View PubMed
  373. Ramanan VK, Wang X, Przybelski SA, Raghavan S, Heckman MG, Batzler A, Kosel ML, Hohman TJ, Knopman DS, Graff-Radford J, Lowe VJ, Mielke MM, Jack CR Jr, Petersen RC, Ross OA, Vemuri P. Variants in PPP2R2B and IGF2BP3 are associated with higher tau deposition. Brain Commun. 2020; 2 (2):fcaa159 Epub 2020 Sept 26
    View PubMed
  374. Miyagawa T, Brushaber D, Syrjanen J, Kremers W, Fields J, Forsberg LK, Heuer HW, Knopman D, Kornak J, Boxer A, Rosen H, Boeve B, ARTFL/LEFFTDS Consortium. Use of the CDR(R) plus NACC FTLD in mild FTLD: Data from the ARTFL/LEFFTDS consortium. Alzheimers Dement. 2020 Jan; 16 (1):79-90 Epub 2020 Jan 06
    View PubMed
  375. Boeve B, Bove J, Brannelly P, Brushaber D, Coppola G, Dever R, Dheel C, Dickerson B, Dickinson S, Faber K, Fields J, Fong J, Foroud T, Forsberg L, Gavrilova R, Gearhart D, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grossman M, Haley D, Heuer H, Hsiung GR, Huey E, Irwin D, Jones D, Jones L, Kantarci K, Karydas A, Knopman D, Kornak J, Kraft R, Kramer J, Kremers W, Kukull W, Lapid M, Lucente D, Mackenzie I, Manoochehri M, McGinnis S, Miller B, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin K, Rascovsky K, Sengdy P, Shaw L, Syrjanen J, Tatton N, Taylor J, Toga A, Trojanowski J, Weintraub S, Wong B, Wszolek Z, Boxer A, Rosen H, LEFFTDS Consortium. The longitudinal evaluation of familial frontotemporal dementia subjects protocol: Framework and methodology. Alzheimers Dement. 2020 Jan; 16 (1):22-36 Epub 2020 Jan 06
    View PubMed
  376. Krell-Roesch J, Syrjanen JA, Mielke MM, Christianson TJ, Kremers WK, Machulda MM, Knopman DS, Petersen RC, Vassilaki M, Geda YE. Association Between Neuropsychiatric Symptoms and Functional Change in Older Non-Demented Adults: Mayo Clinic Study of Aging. J Alzheimers Dis 2020; 78 (3):911-917
    View PubMed
  377. Mamo SK, Reed NS, Sharrett AR, Albert MS, Coresh J, Mosley TH, Knopman D, Lin FR, Deal JA. Relationship Between Domain-Specific Cognitive Function and Speech-in-Noise Performance in Older Adults: The Atherosclerosis Risk in Communities Hearing Pilot Study. Am J Audiol. 2019 Dec 16; 28 (4):1006-1014 Epub 2019 Dec 11
    View PubMed
  378. Graff-Radford J, Gunter JL, Jones DT, Przybelski SA, Schwarz CG, Huston J 3rd, Lowe V, Elder BD, Machulda MM, Gunter NB, Petersen RC, Kantarci K, Vemuri P, Mielke MM, Knopman DS, Graff-Radford NR, Jack CR Jr. Cerebrospinal fluid dynamics disorders: Relationship to Alzheimer biomarkers and cognition. Neurology. 2019 Dec 10; 93 (24):e2237-e2246 Epub 2019 Nov 12
    View PubMed
  379. Dearborn-Tomazos JL, Wu A, Steffen LM, Anderson CAM, Hu EA, Knopman D, Mosley TH, Gottesman RF. Association of Dietary Patterns in Midlife and Cognitive Function in Later Life in US Adults Without Dementia. JAMA Netw Open. 2019 Dec 2; 2 (12):e1916641 Epub 2019 Dec 02
    View PubMed
  380. Nedelska Z, Schwarz CG, Lesnick TG, Boeve BF, Przybelski SA, Lowe VJ, Kremers WK, Gunter JL, Senjem ML, Graff-Radford J, Ferman TJ, Fields JA, Knopman DS, Petersen RC, Jack CR Jr, Kantarci K. Association of Longitudinal beta-Amyloid Accumulation Determined by Positron Emission Tomography With Clinical and Cognitive Decline in Adults With Probable Lewy Body Dementia. JAMA Netw Open. 2019 Dec 2; 2 (12):e1916439 Epub 2019 Dec 02
    View PubMed
  381. Sprung J, Kruthiventi SC, Warner DO, Knopman DS, Petersen RC, Mielke MM, Jack CR Jr, Graff-Radford J, Martin DP, Hanson AC, Schroeder DR, Przybelski SA, Schulte PJ, Weingarten TN, Vemuri P. Exposure to surgery under general anaesthesia and brain magnetic resonance imaging changes in older adults. Br J Anaesth. 2019 Dec; 123 (6):808-817 Epub 2019 Oct 03
    View PubMed
  382. Johansen MC, Mosley TH, Knopman DS, Wong DF, Wagenknecht LE, Shah AM, Solomon SD, Gottesman RF. Associations Between Left Ventricular Structure, Function, and Cerebral Amyloid: The ARIC-PET Study. Stroke. 2019 Dec; 50 (12):3622-3624 Epub 2019 Oct 10
    View PubMed
  383. Krell-Roesch J, Syrjanen JA, Vassilaki M, Barisch-Fritz B, Trautwein S, Boes K, Woll A, Kremers WK, Machulda MM, Mielke MM, Knopman DS, Petersen RC, Geda YE. Association of non-exercise physical activity in mid- and late-life with cognitive trajectories and the impact of APOE epsilon4 genotype status: the Mayo Clinic Study of Aging. Eur J Ageing. 2019 Dec; 16 (4):491-502 Epub 2019 Apr 12
    View PubMed
  384. Kornak J, Fields J, Kremers W, Farmer S, Heuer HW, Forsberg L, Brushaber D, Rindels A, Dodge H, Weintraub S, Besser L, Appleby B, Bordelon Y, Bove J, Brannelly P, Caso C, Coppola G, Dever R, Dheel C, Dickerson B, Dickinson S, Dominguez S, Domoto-Reilly K, Faber K, Ferrall J, Fishman A, Fong J, Foroud T, Gavrilova R, Gearhart D, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant IM, Grossman M, Haley D, Hsiao J, Hsiung R, Huey ED, Irwin D, Jones D, Jones L, Kantarci K, Karydas A, Kaufer D, Kerwin D, Knopman D, Kraft R, Kramer J, Kukull W, Lapid M, Litvan I, Ljubenkov P, Lucente D, Lungu C, Mackenzie I, Maldonado M, Manoochehri M, McGinnis S, McKinley E, Mendez M, Miller B, Multani N, Onyike C, Padmanabhan J, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin K, Rascovsky K, Roberson ED, Rogalski-Miller E, Sengdy P, Shaw L, Staffaroni AM, Sutherland M, Syrjanen J, Tartaglia C, Tatton N, Taylor J, Toga A, Trojanowski J, Wang P, Wong B, Wszolek Z, Boeve B, Boxer A, Rosen H, ARTFL/LEFFTDS Consortium. Nonlinear Z-score modeling for improved detection of cognitive abnormality. Alzheimers Dement (Amst). 2019 Dec; 11:797-808 Epub 2019 Dec 05
    View PubMed
  385. Vemuri P, Lesnick TG, Knopman DS, Przybelski SA, Reid RI, Mielke MM, Graff-Radford J, Lowe VJ, Machulda MM, Petersen RC, Jack CR Jr. Amyloid, Vascular, and Resilience Pathways Associated with Cognitive Aging. Ann Neurol. 2019 Dec; 86 (6):866-877 Epub 2019 Oct 17
    View PubMed
  386. Yost M, Fiebelkorn CA, Fiebelkorn CA, Rabinstein AA, Klaas J, Aakre JA, Brown RD Jr, Mielke MM, Knopman DS, Lowe V, Petersen RC, Jack CR Jr, Vemuri P, Graff-Radford J. Incidence of Convexal Subarachnoid Hemorrhage in the Elderly: The Mayo Clinic Study of Aging. J Stroke Cerebrovasc Dis. 2019 Dec; 28 (12):104451 Epub 2019 Oct 24
    View PubMed
  387. Mielke MM, Syrjanen JA, Bui HH, Petersen RC, Knopman DS, Jack CR Jr, Graff-Radford J, Vemuri P. Elevated Plasma Ceramides Are Associated With Higher White Matter Hyperintensity Volume-Brief Report. Arterioscler Thromb Vasc Biol. 2019 Nov; 39 (11):2431-2436 Epub 2019 Sept 12
    View PubMed
  388. Scharf EL, Graff-Radford J, Przybelski SA, Lesnick TG, Mielke MM, Knopman DS, Preboske GM, Schwarz CG, Senjem ML, Gunter JL, Machulda M, Kantarci K, Petersen RC, Jack CR Jr, Vemuri P. Cardiometabolic Health and Longitudinal Progression of White Matter Hyperintensity: The Mayo Clinic Study of Aging. Stroke. 2019 Nov; 50 (11):3037-3044 Epub 2019 Sept 12
    View PubMed
  389. Mielke MM, Syrjanen JA, Blennow K, Zetterberg H, Skoog I, Vemuri P, Machulda MM, Graff-Radford J, Knopman DS, Jack CR Jr, Petersen RC, Kern S. Comparison of variables associated with cerebrospinal fluid neurofilament, total-tau, and neurogranin. Alzheimers Dement. 2019 Nov; 15 (11):1437-1447 Epub 2019 Oct 23
    View PubMed
  390. Pokharel Y, Mouhanna F, Schneider ALC, Rawlings AM, Knopman DS, Nambi V, Virani SS, Hoogeveen RC, Alonso A, Heiss G, Coresh J, Mosley T, Gottesman R, Selvin E, Ballantyne C, Power MC. High-Sensitive Troponin T, Natriuretic Peptide, and Cognitive Change. J Am Geriatr Soc. 2019 Nov; 67 (11):2353-2361 Epub 2019 July 30
    View PubMed
  391. Bejanin A, Murray ME, Martin P, Botha H, Tosakulwong N, Schwarz CG, Senjem ML, Chetelat G, Kantarci K, Jack CR, Boeve BF, Knopman DS, Petersen RC, Giannini C, Parisi JE, Dickson DW, Whitwell JL, Josephs KA. Antemortem volume loss mirrors TDP-43 staging in older adults with non-frontotemporal lobar degeneration. Brain. 2019 Nov 1; 142 (11):3621-3635
    View PubMed
  392. Vassilaki M, Aakre JA, Knopman DS, Kremers WK, Mielke MM, Geda YE, Machulda MM, Al Fakir R, Undavalli C, Roberts RO, Petersen RC. Informant-based hearing difficulties and the risk for mild cognitive impairment and dementia. Age Ageing. 2019 Nov 1; 48 (6):888-894
    View PubMed
  393. Chen Q, Boeve BF, Schwarz CG, Reid R, Tosakulwong N, Lesnick TG, Bove J, Brannelly P, Brushaber D, Coppola G, Dheel C, Dickerson BC, Dickinson S, Faber K, Fields J, Fong J, Foroud T, Forsberg L, Gavrilova RH, Gearhart D, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford NR, Grossman M, Haley D, Heuer HW, Hsiung GR, Huey E, Irwin DJ, Jack CR, Jones DT, Jones L, Karydas AM, Knopman DS, Kornak J, Kramer J, Kremers W, Kukull WA, Lapid M, Lucente D, Lungu C, Mackenzie IRA, Manoochehri M, McGinnis S, Miller BL, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin KP, Rascovsky K, Sengdy P, Shaw L, Syrjanen J, Tatton N, Taylor J, Toga AW, Trojanowski J, Weintraub S, Wong B, Boxer AL, Rosen H, Wszolek Z, Kantarci K, LEFFTDS Consortium. Tracking white matter degeneration in asymptomatic and symptomatic MAPT mutation carriers. Neurobiol Aging. 2019 Nov; 83:54-62 Epub 2019 Aug 15
    View PubMed
  394. Power MC, Su D, Wu A, Reid RI, Jack CR, Knopman DS, Coresh J, Huang J, Kantarci K, Sharrett AR, Gottesman RG, Griswold ME, Mosley TH. Association of white matter microstructural integrity with cognition and dementia. Neurobiol Aging. 2019 Nov; 83:63-72 Epub 2019 Aug 29
    View PubMed
  395. Schwarz CG, Kremers WK, Therneau TM, Sharp RR, Gunter JL, Vemuri P, Arani A, Spychalla AJ, Kantarci K, Knopman DS, Petersen RC, Jack CR Jr. Identification of Anonymous MRI Research Participants with Face-Recognition Software. N Engl J Med 2019 Oct 24; 381 (17):1684-1686
    View PubMed
  396. Dickson DW, Baker MC, Jackson JL, DeJesus-Hernandez M, Finch NA, Tian S, Heckman MG, Pottier C, Gendron TF, Murray ME, Ren Y, Reddy JS, Graff-Radford NR, Boeve BF, Petersen RC, Knopman DS, Josephs KA, Petrucelli L, Oskarsson B, Sheppard JW, Asmann YW, Rademakers R, van Blitterswijk M. Extensive transcriptomic study emphasizes importance of vesicular transport in C9orf72 expansion carriers. Acta Neuropathol Commun. 2019 Oct 8; 7 (1):150 Epub 2019 Oct 08
    View PubMed
  397. Ramanan VK, Castillo AM, Knopman DS, Graff-Radford J, Lowe VJ, Petersen RC, Jack CR Jr, Mielke MM, Vemuri P. Association of Apolipoprotein E varepsilon4, Educational Level, and Sex With Tau Deposition and Tau-Mediated Metabolic Dysfunction in Older Adults. JAMA Netw Open. 2019 Oct 2; 2 (10):e1913909 Epub 2019 Oct 02
    View PubMed
  398. Jack CR Jr, Therneau TM, Weigand SD, Wiste HJ, Knopman DS, Vemuri P, Lowe VJ, Mielke MM, Roberts RO, Machulda MM, Graff-Radford J, Jones DT, Schwarz CG, Gunter JL, Senjem ML, Rocca WA, Petersen RC. Prevalence of Biologically vs Clinically Defined Alzheimer Spectrum Entities Using the National Institute on Aging-Alzheimer's Association Research Framework. JAMA Neurol 2019 Oct 1; 76 (10):1174-1183
    View PubMed
  399. Zhou X, Wang Y, Sohn S, Therneau TM, Liu H, Knopman DS. Automatic extraction and assessment of lifestyle exposures for Alzheimer's disease using natural language processing. Int J Med Inform. 2019 Oct; 130:103943 Epub 2019 Aug 06
    View PubMed
  400. Jack CR, Wiste HJ, Botha H, Weigand SD, Therneau TM, Knopman DS, Graff-Radford J, Jones DT, Ferman TJ, Boeve BF, Kantarci K, Lowe VJ, Vemuri P, Mielke MM, Fields JA, Machulda MM, Schwarz CG, Senjem ML, Gunter JL, Petersen RC. The bivariate distribution of amyloid-beta and tau: relationship with established neurocognitive clinical syndromes. Brain. 2019 Oct 1; 142 (10):3230-3242
    View PubMed
  401. Sprung J, Schulte PJ, Knopman DS, Mielke MM, Petersen RC, Weingarten TN, Martin DP, Hanson AC, Schroeder DR, Warner DO. Cognitive function after surgery with regional or general anesthesia: A population-based study. Alzheimers Dement. 2019 Oct; 15 (10):1243-1252 Epub 2019 Sept 05
    View PubMed
  402. Windham BG, Griswold ME, Wilkening SR, Su D, Tingle J, Coker LH, Knopman D, Gottesman RF, Shibata D, Mosley TH. Midlife Smaller and Larger Infarctions, White Matter Hyperintensities, and 20-Year Cognitive Decline: A Cohort Study. Ann Intern Med. 2019 Sep 17; 171 (6):389-396 Epub 2019 Aug 27
    View PubMed
  403. Chen Q, Boeve BF, Tosakulwong N, Lesnick T, Brushaber D, Dheel C, Fields J, Forsberg L, Gavrilova R, Gearhart D, Haley D, Gunter JL, Graff-Radford J, Jones D, Knopman D, Graff-Radford N, Kraft R, Lapid M, Rademakers R, Wszolek ZK, Rosen H, Boxer AL, Kantarci K. Brain MR Spectroscopy Changes Precede Frontotemporal Lobar Degeneration Phenoconversion in Mapt Mutation Carriers. J Neuroimaging. 2019 Sep; 29 (5):624-629 Epub 2019 June 07
    View PubMed
  404. Chen Q, Boeve BF, Tosakulwong N, Lesnick T, Brushaber D, Dheel C, Fields J, Forsberg L, Gavrilova R, Gearhart D, Haley D, Gunter JL, Graff-Radford J, Jones D, Knopman D, Graff-Radford N, Kraft R, Lapid M, Rademakers R, Syrjanen J, Wszolek ZK, Rosen H, Boxer AL, Kantarci K. Frontal lobe (1)H MR spectroscopy in asymptomatic and symptomatic MAPT mutation carriers. Neurology. 2019 Aug 20; 93 (8):e758-e765 Epub 2019 July 17
    View PubMed
  405. Walker KA, Sharrett AR, Wu A, Schneider ALC, Albert M, Lutsey PL, Bandeen-Roche K, Coresh J, Gross AL, Windham BG, Knopman DS, Power MC, Rawlings AM, Mosley TH, Gottesman RF. Association of Midlife to Late-Life Blood Pressure Patterns With Incident Dementia. JAMA. 2019 Aug 13; 322 (6):535-545
    View PubMed
  406. Krell-Roesch J, Syrjanen JA, Vassilaki M, Machulda MM, Mielke MM, Knopman DS, Kremers WK, Petersen RC, Geda YE. Quantity and quality of mental activities and the risk of incident mild cognitive impairment. Neurology. 2019 Aug 6; 93 (6):e548-e558 Epub 2019 July 10
    View PubMed
  407. Ali F, Martin PR, Botha H, Ahlskog JE, Bower JH, Masumoto JY, Maraganore D, Hassan A, Eggers S, Boeve BF, Knopman DS, Drubach D, Petersen RC, Dunkley ED, van Gerpen J, Uitti R, Whitwell JL, Dickson DW, Josephs KA. Sensitivity and Specificity of Diagnostic Criteria for Progressive Supranuclear Palsy. Mov Disord. 2019 Aug; 34 (8):1144-1153 Epub 2019 Feb 06
    View PubMed
  408. Stricker NH, Lundt ES, Edwards KK, Machulda MM, Kremers WK, Roberts RO, Knopman DS, Petersen RC, Mielke MM. Comparison of PC and iPad administrations of the Cogstate Brief Battery in the Mayo Clinic Study of Aging: Assessing cross-modality equivalence of computerized neuropsychological tests. Clin Neuropsychol. 2019 Aug; 33(6):1102-1126. Epub 2018 Nov 10.
    View PubMed
  409. Schulte PJ, Warner DO, Martin DP, Deljou A, Mielke MM, Knopman DS, Petersen RC, Weingarten TN, Warner MA, Rabinstein AA, Hanson AC, Schroeder DR, Sprung J. Association Between Critical Care Admissions and Cognitive Trajectories in Older Adults. Crit Care Med. 2019 Aug; 47 (8):1116-1124
    View PubMed
  410. Tetzloff KA, Duffy JR, Clark HM, Utianski RL, Strand EA, Machulda MM, Botha H, Martin PR, Schwarz CG, Senjem ML, Reid RI, Gunter JL, Spychalla AJ, Knopman DS, Petersen RC, Jack CR, Lowe VJ, Josephs KA, Whitwell JL. Progressive agrammatic aphasia without apraxia of speech as a distinct syndrome. Brain. 2019 Aug 01; 142(8):2466-2482.
    View PubMed
  411. Graff-Radford J, Arenaza-Urquijo EM, Knopman DS, Schwarz CG, Brown RD, Rabinstein AA, Gunter JL, Senjem ML, Przybelski SA, Lesnick T, Ward C, Mielke MM, Lowe VJ, Petersen RC, Kremers WK, Kantarci K, Jack CR, Vemuri P. White matter hyperintensities: relationship to amyloid and tau burden. Brain. 2019 Aug 1; 142 (8):2483-2491
    View PubMed
  412. Townley RA, Syrjanen JA, Botha H, Kremers WK, Aakre JA, Fields JA, Machulda MM, Graff-Radford J, Savica R, Jones DT, Knopman DS, Petersen RC, Boeve BF. Comparison of the Short Test of Mental Status and the Montreal Cognitive Assessment Across the Cognitive Spectrum. Mayo Clin Proc. 2019 Aug; 94 (8):1516-1523 Epub 2019 July 04
    View PubMed
  413. van der Lee SJ, Conway OJ, Jansen I, Carrasquillo MM, Kleineidam L, van den Akker E, Hernandez I, van Eijk KR, Stringa N, Chen JA, Zettergren A, Andlauer TFM, Diez-Fairen M, Simon-Sanchez J, Lleo A, Zetterberg H, Nygaard M, Blauwendraat C, Savage JE, Mengel-From J, Moreno-Grau S, Wagner M, Fortea J, Keogh MJ, Blennow K, Skoog I, Friese MA, Pletnikova O, Zulaica M, Lage C, de Rojas I, Riedel-Heller S, Illan-Gala I, Wei W, Jeune B, Orellana A, Then Bergh F, Wang X, Hulsman M, Beker N, Tesi N, Morris CM, Indakoetxea B, Collij LE, Scherer M, Morenas-Rodriguez E, Ironside JW, van Berckel BNM, Alcolea D, Wiendl H, Strickland SL, Pastor P, Rodriguez Rodriguez E, Boeve BF, Petersen RC, Ferman TJ, van Gerpen JA, Reinders MJT, Uitti RJ, Tarraga L, Maier W, Dols-Icardo O, Kawalia A, Dalmasso MC, Boada M, Zettl UK, van Schoor NM, Beekman M, Allen M, Masliah E, de Munain AL, Pantelyat A, Wszolek ZK, Ross OA, Dickson DW, Graff-Radford NR, Knopman D, Rademakers R, Lemstra AW, Pijnenburg YAL, Scheltens P, Gasser T, Chinnery PF, Hemmer B, Huisman MA, Troncoso J, Moreno F, Nohr EA, Sorensen TIA, Heutink P, Sanchez-Juan P, Posthuma D, Clarimon J, Christensen K, Ertekin-Taner N, Scholz SW, Ramirez A, Ruiz A, Slagboom E, van der Flier WM, Holstege H, DESGESCO (Dementia Genetics Spanish Consortium), EADB (Alzheimer Disease European DNA biobank)//EADB (Alzheimer Disease European DNA biobank)//IFGC (International FTD-Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Consortium)//IPDGC (The International Parkinson Disease G. A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity. Acta Neuropathol. 2019 Aug; 138 (2):237-250 Epub 2019 May 27
    View PubMed
  414. Mielke MM, Syrjanen JA, Blennow K, Zetterberg H, Vemuri P, Skoog I, Machulda MM, Kremers WK, Knopman DS, Jack C Jr, Petersen RC, Kern S. Plasma and CSF neurofilament light: Relation to longitudinal neuroimaging and cognitive measures. Neurology. 2019 Jul 16; 93 (3):e252-e260 Epub 2019 June 10
    View PubMed
  415. Wennberg AMV, Hagen CE, Machulda MM, Knopman DS, Petersen RC, Mielke MM. The Cross-sectional and Longitudinal Associations Between IL-6, IL-10, and TNFalpha and Cognitive Outcomes in the Mayo Clinic Study of Aging. J Gerontol A Biol Sci Med Sci. 2019 Jul 12; 74 (8):1289-1295
    View PubMed
  416. Lowe VJ, Bruinsma TJ, Wiste HJ, Min HK, Weigand SD, Fang P, Senjem ML, Therneau TM, Boeve BF, Josephs KA, Pandey MK, Murray ME, Kantarci K, Jones DT, Vemuri P, Graff-Radford J, Schwarz CG, Machulda MM, Mielke MM, Roberts RO, Knopman DS, Petersen RC, Jack CR Jr. Cross-sectional associations of tau-PET signal with cognition in cognitively unimpaired adults. Neurology. 2019 Jul 2; 93 (1):e29-e39 Epub 2019 May 30
    View PubMed
  417. Lowe VJ, Lundt ES, Albertson SM, Przybelski SA, Senjem ML, Parisi JE, Kantarci K, Boeve B, Jones DT, Knopman D, Jack CR Jr, Dickson DW, Petersen RC, Murray ME. Neuroimaging correlates with neuropathologic schemes in neurodegenerative disease. Alzheimers Dement. 2019 Jul; 15 (7):927-939 Epub 2019 June 04
    View PubMed
  418. Li D, Hagen C, Fett AR, Bui HH, Knopman D, Vemuri P, Machulda MM, Jack CR Jr, Petersen RC, Mielke MM. Longitudinal association between phosphatidylcholines, neuroimaging measures of Alzheimer's disease pathophysiology, and cognition in the Mayo Clinic Study of Aging. Neurobiol Aging. 2019 Jul; 79:43-49 Epub 2019 Mar 18
    View PubMed
  419. Machulda MM, Lundt ES, Albertson SM, Kremers WK, Mielke MM, Knopman DS, Bondi MW, Petersen RC. Neuropsychological subtypes of incident mild cognitive impairment in the Mayo Clinic Study of Aging. Alzheimers Dement. 2019 Jul; 15 (7):878-887 Epub 2019 May 23
    View PubMed
  420. Rawlings AM, Sharrett AR, Albert MS, Coresh J, Windham BG, Power MC, Knopman DS, Walker K, Burgard S, Mosley TH, Gottesman RF, Selvin E. The Association of Late-Life Diabetes Status and Hyperglycemia With Incident Mild Cognitive Impairment and Dementia: The ARIC Study. Diabetes Care. 2019 Jul; 42 (7):1248-1254 Epub 2019 May 21
    View PubMed
  421. Jack CR Jr, Wiste HJ, Therneau TM, Weigand SD, Knopman DS, Mielke MM, Lowe VJ, Vemuri P, Machulda MM, Schwarz CG, Gunter JL, Senjem ML, Graff-Radford J, Jones DT, Roberts RO, Rocca WA, Petersen RC. Associations of Amyloid, Tau, and Neurodegeneration Biomarker Profiles With Rates of Memory Decline Among Individuals Without Dementia. JAMA. 2019 Jun 18; 321 (23):2316-2325
    View PubMed
  422. Lutsey PL, Chen N, Mirabelli MC, Lakshminarayan K, Knopman DS, Vossel KA, Gottesman RF, Mosley TH, Alonso A. Impaired Lung Function, Lung Disease, and Risk of Incident Dementia. Am J Respir Crit Care Med. 2019 Jun 1; 199 (11):1385-1396
    View PubMed
  423. Pottier C, Ren Y, Perkerson RB 3rd, Baker M, Jenkins GD, van Blitterswijk M, DeJesus-Hernandez M, van Rooij JGJ, Murray ME, Christopher E, McDonnell SK, Fogarty Z, Batzler A, Tian S, Vicente CT, Matchett B, Karydas AM, Hsiung GR, Seelaar H, Mol MO, Finger EC, Graff C, Oijerstedt L, Neumann M, Heutink P, Synofzik M, Wilke C, Prudlo J, Rizzu P, Simon-Sanchez J, Edbauer D, Roeber S, Diehl-Schmid J, Evers BM, King A, Mesulam MM, Weintraub S, Geula C, Bieniek KF, Petrucelli L, Ahern GL, Reiman EM, Woodruff BK, Caselli RJ, Huey ED, Farlow MR, Grafman J, Mead S, Grinberg LT, Spina S, Grossman M, Irwin DJ, Lee EB, Suh E, Snowden J, Mann D, Ertekin-Taner N, Uitti RJ, Wszolek ZK, Josephs KA, Parisi JE, Knopman DS, Petersen RC, Hodges JR, Piguet O, Geier EG, Yokoyama JS, Rissman RA, Rogaeva E, Keith J, Zinman L, Tartaglia MC, Cairns NJ, Cruchaga C, Ghetti B, Kofler J, Lopez OL, Beach TG, Arzberger T, Herms J, Honig LS, Vonsattel JP, Halliday GM, Kwok JB, White CL 3rd, Gearing M, Glass J, Rollinson S, Pickering-Brown S, Rohrer JD, Trojanowski JQ, Van Deerlin V, Bigio EH, Troakes C, Al-Sarraj S, Asmann Y, Miller BL, Graff-Radford NR, Boeve BF, Seeley WW, Mackenzie IRA, van Swieten JC, Dickson DW, Biernacka JM, Rademakers R. Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD. Acta Neuropathol. 2019 Jun; 137 (6):879-899 Epub 2019 Feb 09
    View PubMed
  424. Boeve A, Ferman TJ, Aakre J, St Louis E, Silber M, Machulda M, Fields J, Graff-Radford N, Mielke M, Geda Y, Jones D, Graff-Radford J, Knopman D, Petersen R, Boeve B. Excessive Daytime Sleepiness in Major Dementia Syndromes. Am J Alzheimers Dis Other Demen. 2019 Jun; 34 (4):261-264 Epub 2019 Feb 10
    View PubMed
  425. Josephs KA, Murray ME, Tosakulwong N, Weigand SD, Knopman DS, Petersen RC, Jack CR Jr, Whitwell JL, Dickson DW. Brain atrophy in primary age-related tauopathy is linked to transactive response DNA-binding protein of 43 kDa. Alzheimers Dement. 2019 Jun; 15 (6):799-806 Epub 2019 May 02
    View PubMed
  426. Knopman DS, Petersen RC, Jack CR Jr. A brief history of "Alzheimer disease": Multiple meanings separated by a common name. Neurology. 2019 May 28; 92 (22):1053-1059 Epub 2019 Apr 26
    View PubMed
  427. Vassilaki M, Aakre JA, Kremers WK, Mielke MM, Geda YE, Alhurani RE, Dutt T, Machulda MM, Knopman DS, Vemuri P, Coloma PM, Schauble B, Lowe VJ, Jack CR, Petersen RC, Roberts RO. The Association of Multimorbidity With Preclinical AD Stages and SNAP in Cognitively Unimpaired Persons. J Gerontol A Biol Sci Med Sci. 2019 May 16; 74 (6):877-883
    View PubMed
  428. Staffaroni AM, Bajorek L, Casaletto KB, Cobigo Y, Goh SM, Wolf A, Heuer HW, Elahi FM, Ljubenkov PA, Dever R, Kornak J, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dheel C, Dickerson BC, Dickinson S, Dominguez S, Domoto-Reilly K, Faber K, Ferrall J, Fields JA, Fishman A, Fong J, Foroud T, Forsberg LK, Gavrilova R, Gearhart D, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant I, Grossman M, Haley D, Hsiung GY, Huey ED, Irwin DJ, Jones DT, Jones L, Kantarci K, Karydas A, Kaufer DI, Kerwin DR, Knopman DS, Kraft R, Kremers WK, Kukull WA, Litvan I, Lucente D, Lungu C, Mackenzie IR, Maldonado M, Manoochehri M, McGinnis SM, McKinley E, Mendez MF, Miller BL, Multani N, Onyike C, Padmanabhan J, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin KP, Rascovsky K, Roberson ED, Rogalski E, Sengdy P, Shaw LM, Syrjanen J, Tartaglia MC, Tatton N, Taylor J, Toga A, Trojanowski JQ, Weintraub S, Wang P, Wong B, Wszolek Z, Boxer AL, Boeve BF, Kramer JH, Rosen HJ, ARTFL/LEFFTDS consortium. Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint. Alzheimers Dement. 2019 May 11 [Epub ahead of print]
    View PubMed
  429. Wu A, Sharrett AR, Gottesman RF, Power MC, Mosley TH Jr, Jack CR Jr, Knopman DS, Windham BG, Gross AL, Coresh J. Association of Brain Magnetic Resonance Imaging Signs With Cognitive Outcomes in Persons With Nonimpaired Cognition and Mild Cognitive Impairment. JAMA Netw Open. 2019 May 3; 2 (5):e193359 Epub 2019 May 03
    View PubMed
  430. Wennberg AM, Whitwell JL, Tosakulwong N, Weigand SD, Murray ME, Machulda MM, Petrucelli L, Mielke MM, Jack CR Jr, Knopman DS, Parisi JE, Petersen RC, Dickson DW, Josephs KA. The influence of tau, amyloid, alpha-synuclein, TDP-43, and vascular pathology in clinically normal elderly individuals. Neurobiol Aging. 2019 May; 77:26-36 Epub 2019 Jan 21
    View PubMed
  431. Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoumaki S, Giddaluru S, Gustavson DE, Hayward C, Hofer E, Ikram MA, Karlsson R, Knowles E, Lahti J, Leber M, Li S, Mather KA, Melle I, Morris D, Oldmeadow C, Palviainen T, Payton A, Pazoki R, Petrovic K, Reynolds CA, Sargurupremraj M, Scholz M, Smith JA, Smith AV, Terzikhan N, Thalamuthu A, Trompet S, van der Lee SJ, Ware EB, Windham BG, Wright MJ, Yang J, Yu J, Ames D, Amin N, Amouyel P, Andreassen OA, Armstrong NJ, Assareh AA, Attia JR, Attix D, Avramopoulos D, Bennett DA, Bohmer AC, Boyle PA, Brodaty H, Campbell H, Cannon TD, Cirulli ET, Congdon E, Conley ED, Corley J, Cox SR, Dale AM, Dehghan A, Dick D, Dickinson D, Eriksson JG, Evangelou E, Faul JD, Ford I, Freimer NA, Gao H, Giegling I, Gillespie NA, Gordon SD, Gottesman RF, Griswold ME, Gudnason V, Harris TB, Hartmann AM, Hatzimanolis A, Heiss G, Holliday EG, Joshi PK, Kahonen M, Kardia SLR, Karlsson I, Kleineidam L, Knopman DS, Kochan NA, Konte B, Kwok JB, Le Hellard S, Lee T, Lehtimaki T, Li SC, Lill CM, Liu T, Koini M, London E, Longstreth WT Jr, Lopez OL, Loukola A, Luck T, Lundervold AJ, Lundquist A, Lyytikainen LP, Martin NG, Montgomery GW, Murray AD, Need AC, Noordam R, Nyberg L, Ollier W, Papenberg G, Pattie A, Polasek O, Poldrack RA, Psaty BM, Reppermund S, Riedel-Heller SG, Rose RJ, Rotter JI, Roussos P, Rovio SP, Saba Y, Sabb FW, Sachdev PS, Satizabal CL, Schmid M, Scott RJ, Scult MA, Simino J, Slagboom PE, Smyrnis N, Soumare A, Stefanis NC, Stott DJ, Straub RE, Sundet K, Taylor AM, Taylor KD, Tzoulaki I, Tzourio C, Uitterlinden A, Vitart V, Voineskos AN, Kaprio J, Wagner M, Wagner H, Weinhold L, Wen KH, Widen E, Yang Q, Zhao W, Adams HHH, Arking DE, Bilder RM, Bitsios P, Boerwinkle E, Chiba-Falek O, Corvin A, De Jager PL, Debette S, Donohoe G, Elliott P, Fitzpatrick AL, Gill M, Glahn DC, Hagg S, Hansell NK, Hariri AR, Ikram MK, Jukema JW, Vuoksimaa E, Keller MC, Kremen WS, Launer L, Lindenberger U, Palotie A, Pedersen NL, Pendleton N, Porteous DJ, Raikkonen K, Raitakari OT, Ramirez A, Reinvang I, Rudan I, Dan Rujescu Rujescu, Schmidt R, Schmidt H, Schofield PW, Schofield PR, Starr JM, Steen VM, Trollor JN, Turner ST, Van Duijn CM, Villringer A, Weinberger DR, Weir DR, Wilson JF, Malhotra A, McIntosh AM, Gale CR, Seshadri S, Mosley TH Jr, Bressler J, Lencz T, Deary IJ. Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. Nat Commun. 2019 May 1; 10 (1):2068 Epub 2019 May 01
    View PubMed
  432. Li D, Misialek JR, Jack CR, Mielke MM, Knopman D, Gottesman R, Mosley T, Alonso A. Plasma Metabolites Associated with Brain MRI Measures of Neurodegeneration in Older Adults in the Atherosclerosis Risk in Communities(-)Neurocognitive Study (ARIC-NCS). Int J Mol Sci. 2019 Apr 9; 20 (7) Epub 2019 Apr 09
    View PubMed
  433. Arenaza-Urquijo EM, Przybelski SA, Lesnick TL, Graff-Radford J, Machulda MM, Knopman DS, Schwarz CG, Lowe VJ, Mielke MM, Petersen RC, Jack CR, Vemuri P. The metabolic brain signature of cognitive resilience in the 80+: beyond Alzheimer pathologies. Brain. 2019 Apr 1; 142 (4):1134-1147
    View PubMed
  434. Knopman DS, Lundt ES, Therneau TM, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Boeve BF, Jones DT, Graff-Radford J, Albertson SM, Schwarz CG, Petersen RC, Jack CR. Entorhinal cortex tau, amyloid-beta, cortical thickness and memory performance in non-demented subjects. Brain. 2019 Apr 1; 142 (4):1148-1160
    View PubMed
  435. Zeydan B, Schwarz CG, Lowe VJ, Reid RI, Przybelski SA, Lesnick TG, Kremers WK, Senjem ML, Gunter JL, Min HK, Vemuri P, Knopman DS, Petersen RC, Jack CR Jr, Kantarci OH, Kantarci K. Investigation of white matter PiB uptake as a marker of white matter integrity. Ann Clin Transl Neurol. 2019 Apr; 6 (4):678-688 Epub 2019 Mar 03
    View PubMed
  436. Krell-Roesch J, Vassilaki M, Mielke MM, Kremers WK, Lowe VJ, Vemuri P, Machulda MM, Christianson TJ, Syrjanen JA, Stokin GB, Butler LM, Traber M, Jack CR Jr, Knopman DS, Roberts RO, Petersen RC, Geda YE. Cortical beta-amyloid burden, neuropsychiatric symptoms, and cognitive status: the Mayo Clinic Study of Aging. Transl Psychiatry. 2019 Mar 28; 9 (1):123
    View PubMed
  437. Walker KA, Gottesman RF, Wu A, Knopman DS, Gross AL, Mosley TH Jr, Selvin E, Windham BG. Systemic inflammation during midlife and cognitive change over 20 years: The ARIC Study. Neurology. 2019 Mar 12; 92 (11):e1256-e1267 Epub 2019 Feb 13
    View PubMed
  438. Schneider ALC, Senjem ML, Wu A, Gross A, Knopman DS, Gunter JL, Schwarz CG, Mosley TH, Gottesman RF, Sharrett AR, Jack CR Jr. Neural correlates of domain-specific cognitive decline: The ARIC-NCS Study. Neurology. 2019 Mar 5; 92 (10):e1051-e1063 Epub 2019 Feb 06
    View PubMed
  439. Nedelska Z, Josephs KA, Graff-Radford J, Przybelski SA, Lesnick TG, Boeve BF, Drubach DA, Knopman DS, Petersen RC, Jack CR Jr, Lowe VJ, Whitwell JL, Kantarci K. (18) F-AV-1451 uptake differs between dementia with lewy bodies and posterior cortical atrophy. Mov Disord. 2019 Mar; 34 (3):344-352 Epub 2019 Jan 07
    View PubMed
  440. Deal JA, Sharrett AR, Albert M, Bandeen-Roche K, Burgard S, Thomas SD, Gottesman RF, Knopman D, Mosley T, Klein B, Klein R. Retinal signs and risk of incident dementia in the Atherosclerosis Risk in Communities study. Alzheimers Dement. 2019 Mar; 15 (3):477-486 Epub 2018 Nov 12
    View PubMed
  441. West NA, Windham BG, Knopman DS, Shibata DK, Coker LH, Mosley TH Jr. Neuroimaging findings in midlife and risk of late-life dementia over 20 years of follow-up. Neurology. 2019 Feb 26; 92 (9):e917-e923 Epub 2019 Jan 18
    View PubMed
  442. Whitwell JL, Martin PR, Duffy JR, Clark HM, Machulda MM, Schwarz CG, Weigand SD, Sintini I, Senjem ML, Ertekin-Taner N, Botha H, Utianski RL, Graff-Radford J, Jones DT, Boeve BF, Knopman DS, Petersen RC, Jack CR Jr, Lowe VJ, Josephs KA. The influence of beta-amyloid on [(18)F]AV-1451 in semantic variant of primary progressive aphasia. Neurology. 2019 Feb 12; 92 (7):e710-e722 Epub 2019 Jan 11
    View PubMed
  443. Knopman DS. Bad news and good news in AD, and how to reconcile them. Nat Rev Neurol. 2019 Feb; 15 (2):61-62
    View PubMed
  444. Staffaroni AM, Ljubenkov PA, Kornak J, Cobigo Y, Datta S, Marx G, Walters SM, Chiang K, Olney N, Elahi FM, Knopman DS, Dickerson BC, Boeve BF, Gorno-Tempini ML, Spina S, Grinberg LT, Seeley WW, Miller BL, Kramer JH, Boxer AL, Rosen HJ. Longitudinal multimodal imaging and clinical endpoints for frontotemporal dementia clinical trials. Brain. 2019 Feb 1; 142 (2):443-459
    View PubMed
  445. Josephs KA, Murray ME, Tosakulwong N, Weigand SD, Serie AM, Perkerson RB, Matchett BJ, Jack CR Jr, Knopman DS, Petersen RC, Parisi JE, Petrucelli L, Baker M, Rademakers R, Whitwell JL, Dickson DW. Pathological, imaging and genetic characteristics support the existence of distinct TDP-43 types in non-FTLD brains. Acta Neuropathol. 2019 Feb; 137 (2):227-238 Epub 2019 Jan 02
    View PubMed
  446. Kern S, Syrjanen JA, Blennow K, Zetterberg H, Skoog I, Waern M, Hagen CE, van Harten AC, Knopman DS, Jack CR Jr, Petersen RC, Mielke MM. Association of Cerebrospinal Fluid Neurofilament Light Protein With Risk of Mild Cognitive Impairment Among Individuals Without Cognitive Impairment. JAMA Neurol. 2019 Feb 1; 76 (2):187-193
    View PubMed
  447. Palta P, Sharrett AR, Deal JA, Evenson KR, Gabriel KP, Folsom AR, Gross AL, Windham BG, Knopman D, Mosley TH, Heiss G. Leisure-time physical activity sustained since midlife and preservation of cognitive function: The Atherosclerosis Risk in Communities Study. Alzheimers Dement. 2019 Feb; 15 (2):273-281 Epub 2018 Oct 12
    View PubMed
  448. Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, Mazoyer B, Zhu YC, Kaffashian S, Schilling S, Beecham GW, Montine TJ, Schellenberg GD, Kjartansson O, Guethnason V, Knopman DS, Griswold ME, Windham BG, Gottesman RF, Mosley TH, Schmidt R, Saba Y, Schmidt H, Takeuchi F, Yamaguchi S, Nabika T, Kato N, Rajan KB, Aggarwal NT, De Jager PL, Evans DA, Psaty BM, Rotter JI, Rice K, Lopez OL, Liao J, Chen C, Cheng CY, Wong TY, Ikram MK, van der Lee SJ, Amin N, Chouraki V, DeStefano AL, Aparicio HJ, Romero JR, Maillard P, DeCarli C, Wardlaw JM, Hernandez MDCV, Luciano M, Liewald D, Deary IJ, Starr JM, Bastin ME, Munoz Maniega S, Slagboom PE, Beekman M, Deelen J, Uh HW, Lemmens R, Brodaty H, Wright MJ, Ames D, Boncoraglio GB, Hopewell JC, Beecham AH, Blanton SH, Wright CB, Sacco RL, Wen W, Thalamuthu A, Armstrong NJ, Chong E, Schofield PR, Kwok JB, van der Grond J, Stott DJ, Ford I, Jukema JW, Vernooij MW, Hofman A, Uitterlinden AG, van der Lugt A, Wittfeld K, Grabe HJ, Hosten N, von Sarnowski B, Volker U, Levi C, Jimenez-Conde J, Sharma P, Sudlow CLM, Rosand J, Woo D, Cole JW, Meschia JF, Slowik A, Thijs V, Lindgren A, Melander O, Grewal RP, Rundek T, Rexrode K, Rothwell PM, Arnett DK, Jern C, Johnson JA, Benavente OR, Wasssertheil-Smoller S, Lee JM, Wong Q, Mitchell BD, Rich SS, McArdle PF, Geerlings MI, van der Graaf Y, de Bakker PIW, Asselbergs FW, Srikanth V, Thomson R, McWhirter R, Moran C, Callisaya M, Phan T, Rutten-Jacobs LCA, Bevan S, Tzourio C, Mather KA, Sachdev PS, van Duijn CM, Worrall BB, Dichgans M, Kittner SJ, Markus HS, Ikram MA, Fornage M, Launer LJ, Seshadri S, Longstreth WT Jr, Debette S, Stroke Genetics Network (SiGN), the International Stroke Genetics Consortium (ISGC), METASTROKE, Alzheimer's Disease Genetics Consortium (ADGC), and the Neurology Working Group of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium. Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting. Neurology. 2019 Jan 28; 92 (5):e486-e503
    View PubMed
  449. Palta P, Sharrett AR, Wei J, Meyer ML, Kucharska-Newton A, Power MC, Deal JA, Jack CR, Knopman D, Wright J, Griswold M, Tanaka H, Mosley TH, Heiss G. Central Arterial Stiffness Is Associated With Structural Brain Damage and Poorer Cognitive Performance: The ARIC Study. J Am Heart Assoc. 2019 Jan 22; 8 (2):e011045
    View PubMed
  450. Graff-Radford J, Botha H, Rabinstein AA, Gunter JL, Przybelski SA, Lesnick T, Huston J 3rd, Flemming KD, Preboske GM, Senjem ML, Brown RD Jr, Mielke MM, Roberts RO, Lowe VJ, Knopman DS, Petersen RC, Kremers W, Vemuri P, Jack CR Jr, Kantarci K. Cerebral microbleeds: Prevalence and relationship to amyloid burden. Neurology. 2019 Jan 15; 92 (3):e253-e262 Epub 2018 Dec 19
    View PubMed
  451. Rawlings AM, Sharrett AR, Mosley TH, Wong DF, Knopman DS, Gottesman RF. Cognitive Reserve in Midlife is not Associated with Amyloid-beta Deposition in Late-Life. J Alzheimers Dis. 2019; 68 (2):517-521
    View PubMed
  452. Schwarz CG, Gunter JL, Lowe VJ, Weigand S, Vemuri P, Senjem ML, Petersen RC, Knopman DS, Jack CR. A Comparison of Partial Volume Correction Techniques for Measuring Change in Serial Amyloid PET SUVR. J Alzheimers Dis. 2019; 67 (1):181-195
    View PubMed
  453. Gunter NB, Schwarz CG, Graff-Radford J, Gunter JL, Jones DT, Graff-Radford NR, Petersen RC, Knopman DS, Jack CR Jr. Automated detection of imaging features of disproportionately enlarged subarachnoid space hydrocephalus using machine learning methods. Neuroimage Clin. 2019; 21:101605 Epub 2018 Nov 19
    View PubMed
  454. Whitwell JL, Tosakulwong N, Schwarz CG, Botha H, Senjem ML, Spychalla AJ, Ahlskog JE, Knopman DS, Petersen RC, Jack CR Jr, Lowe VJ, Josephs KA. MRI Outperforms [18F]AV-1451 PET as a Longitudinal Biomarker in Progressive Supranuclear Palsy. Mov Disord. 2019 Jan; 34 (1):105-113 Epub 2018 Nov 23
    View PubMed
  455. Petersen RC, Lundt ES, Therneau TM, Weigand SD, Knopman DS, Mielke MM, Roberts RO, Lowe VJ, Machulda MM, Kremers WK, Geda YE, Jack CR Jr. Predicting Progression to Mild Cognitive Impairment. Ann Neurol. 2019 Jan; 85 (1):155-160 Epub 2019 Jan 07
    View PubMed
  456. Knopman DS. Early-Phase Randomized Clinical Trials-Expectations vs Hard Reality. JAMA Neurol 2019 Jan 1; 76 (1):15-16
    View PubMed
  457. Sintini I, Martin PR, Graff-Radford J, Senjem ML, Schwarz CG, Machulda MM, Spychalla AJ, Drubach DA, Knopman DS, Petersen RC, Lowe VJ, Jack CR Jr, Josephs KA, Whitwell JL. Longitudinal tau-PET uptake and atrophy in atypical Alzheimer's disease. Neuroimage Clin. 2019; 23:101823 Epub 2019 Apr 10
    View PubMed
  458. Krell-Roesch J, Cerhan LP, Machulda MM, Roberts RO, Mielke MM, Knopman DS, Syrjanen JA, Christianson TJ, Petersen RC, Geda YE. Functional Activity and Neuropsychiatric Symptoms in Normal Aging and Mild Cognitive Impairment: The Mayo Clinic Study of Aging. Alzheimer Dis Assoc Disord. 2019 Jan-Mar; 33 (1):68-71
    View PubMed
  459. Neth BJ, Graff-Radford J, Mielke MM, Przybelski SA, Lesnick TG, Schwarz CG, Reid RI, Senjem ML, Lowe VJ, Machulda MM, Petersen RC, Jack CR Jr, Knopman DS, Vemuri P. Relationship Between Risk Factors and Brain Reserve in Late Middle Age: Implications for Cognitive Aging. Front Aging Neurosci. 2019; 11:355 Epub 2020 Jan 09
    View PubMed
  460. Chen Q, Boeve BF, Senjem M, Tosakulwong N, Lesnick TG, Brushaber D, Dheel C, Fields J, Forsberg L, Gavrilova R, Gearhart D, Graff-Radford J, Graff-Radford NR, Jack CR Jr, Jones DT, Knopman DS, Kremers WK, Lapid M, Rademakers R, Syrjanen J, Boxer AL, Rosen H, Wszolek ZK, Kantarci K, LEFFTDS Consortium. Rates of lobar atrophy in asymptomatic MAPT mutation carriers. Alzheimers Dement (N Y). 2019; 5:338-346 Epub 2019 July 30
    View PubMed
  461. Wang F, Lesser ER, Cutsforth-Gregory JK, Bhatti MT, Kilgore KP, Hodge DO, Graff-Radford J, Petersen RC, Knopman DS, Mielke MM, Lanzino G, Leavitt JA, Chen JJ. Population-Based Evaluation of Lumbar Puncture Opening Pressures. Front Neurol. 2019; 10:899 Epub 2019 Aug 16
    View PubMed
  462. Battle MR, Pillay LC, Lowe VJ, Knopman D, Kemp B, Rowe CC, Dore V, Villemagne VL, Buckley CJ. Centiloid scaling for quantification of brain amyloid with [(18)F]flutemetamol using multiple processing methods. EJNMMI Res. 2018 Dec 5; 8 (1):107 Epub 2018 Dec 05
    View PubMed
  463. Jones DT, Townley RA, Graff-Radford J, Botha H, Knopman DS, Petersen RC, Jack CR Jr, Lowe VJ, Boeve BF. Amyloid- and tau-PET imaging in a familial prion kindred. Neurol Genet. 2018 Dec; 4 (6):e290 Epub 2018 Dec 03
    View PubMed
  464. Vassilaki M, Aakre JA, Kremers WK, Mielke MM, Geda YE, Machulda MM, Knopman DS, Coloma PM, Schauble B, Vemuri P, Lowe VJ, Jack CR Jr, Petersen RC, Roberts RO. Association Between Functional Performance and Alzheimer's Disease Biomarkers in Individuals Without Dementia. J Am Geriatr Soc. 2018 Dec; 66 (12):2274-2281 Epub 2018 Nov 21
    View PubMed
  465. Evered L, Silbert B, Knopman DS, Scott DA, DeKosky ST, Rasmussen LS, Oh ES, Crosby G, Berger M, Eckenhoff RG, Nomenclature Consensus Working Group feminine. Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery-2018. Can J Anaesth. 2018 Nov; 65 (11):1248-1257 Epub 2018 Oct 16
    View PubMed
  466. Evered L, Silbert B, Knopman DS, Scott DA, DeKosky ST, Rasmussen LS, Oh ES, Crosby G, Berger M, Eckenhoff RG, Nomenclature Consensus Working Group. Recommendations for the Nomenclature of Cognitive Change Associated With Anaesthesia and Surgery-2018. Anesth Analg 2018 Nov; 127 (5):1189-1195
    View PubMed
  467. Evered L, Silbert B, Knopman DS, Scott DA, DeKosky ST, Rasmussen LS, Oh ES, Crosby G, Berger M, Eckenhoff RG, Nomenclature Consensus Working Group. Recommendations for the Nomenclature of Cognitive Change Associated with Anaesthesia and Surgery-2018. Anesthesiology. 2018 Nov; 129 (5):872-879
    View PubMed
  468. Evered L, Silbert B, Knopman DS, Scott DA, DeKosky ST, Rasmussen LS, Oh ES, Crosby G, Berger M, Eckenhoff RG, Nomenclature Consensus Working Group. Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery-2018. Br J Anaesth. 2018 Nov; 121 (5):1005-1012 Epub 2018 June 15
    View PubMed
  469. Evered L, Silbert B, Knopman DS, Scott DA, DeKosky ST, Rasmussen LS, Oh ES, Crosby G, Berger M, Eckenhoff RG, Nomenclature Consensus Working Group. Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery-2018. Acta Anaesthesiol Scand. 2018 Nov; 62 (10):1473-1480
    View PubMed
  470. Wennberg AM, Tosakulwong N, Lesnick TG, Murray ME, Whitwell JL, Liesinger AM, Petrucelli L, Boeve BF, Parisi JE, Knopman DS, Petersen RC, Dickson DW, Josephs KA. Association of Apolipoprotein E epsilon4 With Transactive Response DNA-Binding Protein 43. JAMA Neurol. 2018 Nov 1; 75 (11):1347-1354
    View PubMed
  471. Vemuri P, Lesnick TG, Przybelski SA, Graff-Radford J, Reid RI, Lowe VJ, Zuk SM, Senjem ML, Schwarz CG, Gunter JL, Kantarci K, Machulda MM, Mielke MM, Petersen RC, Knopman DS, Jack CR Jr. Development of a cerebrovascular magnetic resonance imaging biomarker for cognitive aging. Ann Neurol. 2018 Nov; 84 (5):705-716 Epub 2018 Oct 25
    View PubMed
  472. Schulte PJ, Martin DP, Deljou A, Sabov M, Roberts RO, Knopman DS, Petersen RC, Weingarten TN, Hanson AC, Schroeder DR, Warner DO, Sprung J. Effect of Cognitive Status on the Receipt of Procedures Requiring Anesthesia and Critical Care Admissions in Older Adults. Mayo Clin Proc. 2018 Nov; 93 (11):1552-1562 Epub 2018 Sept 28
    View PubMed
  473. Knopman DS, Gottesman RF, Sharrett AR, Tapia AL, DavisThomas S, Windham BG, Coker L, Schneider ALC, Alonso A, Coresh J, Albert MS, Mosley TH Jr. Midlife vascular risk factors and midlife cognitive status in relation to prevalence of mild cognitive impairment and dementia in later life: The Atherosclerosis Risk in Communities Study. Alzheimers Dement. 2018 Nov; 14 (11):1406-1415 Epub 2018 May 12
    View PubMed
  474. Utianski RL, Whitwell JL, Schwarz CG, Duffy JR, Botha H, Clark HM, Machulda MM, Senjem ML, Knopman DS, Petersen RC, Jack CR Jr, Lowe VJ, Josephs KA. Tau uptake in agrammatic primary progressive aphasia with and without apraxia of speech. Eur J Neurol. 2018 Nov; 25 (11):1352-1357 Epub 2018 July 26
    View PubMed
  475. Walker KA, Gottesman RF, Wu A, Knopman DS, Mosley TH Jr, Alonso A, Kucharska-Newton A, Brown CH 4th. Association of Hospitalization, Critical Illness, and Infection with Brain Structure in Older Adults. J Am Geriatr Soc. 2018 Oct; 66 (10):1919-1926 Epub 2018 Sept 24
    View PubMed
  476. Besser L, Kukull W, Knopman DS, Chui H, Galasko D, Weintraub S, Jicha G, Carlsson C, Burns J, Quinn J, Sweet RA, Rascovsky K, Teylan M, Beekly D, Thomas G, Bollenbeck M, Monsell S, Mock C, Zhou XH, Thomas N, Robichaud E, Dean M, Hubbard J, Jacka M, Schwabe-Fry K, Wu J, Phelps C, Morris JC, Neuropsychology Work Group, Directors, and Clinical Core leaders of the National Institute on Aging-funded US Alzheimer's Disease Centers. Version 3 of the National Alzheimer's Coordinating Center's Uniform Data Set. Alzheimer Dis Assoc Disord. 2018 Oct-Dec; 32 (4):351-358
    View PubMed
  477. Ljubenkov PA, Staffaroni AM, Rojas JC, Allen IE, Wang P, Heuer H, Karydas A, Kornak J, Cobigo Y, Seeley WW, Grinberg LT, Spina S, Fagan AM, Jerome G, Knopman D, Boeve BF, Dickerson BC, Kramer J, Miller B, Boxer AL, Rosen HJ. Cerebrospinal fluid biomarkers predict frontotemporal dementia trajectory. Ann Clin Transl Neurol. 2018 Oct; 5 (10):1250-1263 Epub 2018 Sept 20
    View PubMed
  478. Pakhomov SVS, Eberly LE, Knopman DS. Recurrent perseverations on semantic verbal fluency tasks as an early marker of cognitive impairment. J Clin Exp Neuropsychol. 2018 Oct; 40 (8):832-840 Epub 2018 Mar 04
    View PubMed
  479. Lowe VJ, Lundt ES, Senjem ML, Schwarz CG, Min HK, Przybelski SA, Kantarci K, Knopman D, Petersen RC, Jack CR Jr. White Matter Reference Region in PET Studies of (11)C-Pittsburgh Compound B Uptake: Effects of Age and Amyloid-beta Deposition. J Nucl Med. 2018 Oct; 59 (10):1583-1589 Epub 2018 Apr 19
    View PubMed
  480. Vojinovic D, Adams HH, Jian X, Yang Q, Smith AV, Bis JC, Teumer A, Scholz M, Armstrong NJ, Hofer E, Saba Y, Luciano M, Bernard M, Trompet S, Yang J, Gillespie NA, van der Lee SJ, Neumann A, Ahmad S, Andreassen OA, Ames D, Amin N, Arfanakis K, Bastin ME, Becker DM, Beiser AS, Beyer F, Brodaty H, Bryan RN, Bulow R, Dale AM, De Jager PL, Deary IJ, DeCarli C, Fleischman DA, Gottesman RF, van der Grond J, Gudnason V, Harris TB, Homuth G, Knopman DS, Kwok JB, Lewis CE, Li S, Loeffler M, Lopez OL, Maillard P, El Marroun H, Mather KA, Mosley TH, Muetzel RL, Nauck M, Nyquist PA, Panizzon MS, Pausova Z, Psaty BM, Rice K, Rotter JI, Royle N, Satizabal CL, Schmidt R, Schofield PR, Schreiner PJ, Sidney S, Stott DJ, Thalamuthu A, Uitterlinden AG, Valdes Hernandez MC, Vernooij MW, Wen W, White T, Witte AV, Wittfeld K, Wright MJ, Yanek LR, Tiemeier H, Kremen WS, Bennett DA, Jukema JW, Paus T, Wardlaw JM, Schmidt H, Sachdev PS, Villringer A, Grabe HJ, Longstreth WT, van Duijn CM, Launer LJ, Seshadri S, Ikram MA, Fornage M. Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume. Nat Commun. 2018 Sep 26; 9 (1):3945 Epub 2018 Sept 26
    View PubMed
  481. Dickson DW, Heckman MG, Murray ME, Soto AI, Walton RL, Diehl NN, van Gerpen JA, Uitti RJ, Wszolek ZK, Ertekin-Taner N, Knopman DS, Petersen RC, Graff-Radford NR, Boeve BF, Bu G, Ferman TJ, Ross OA. APOE e4 is associated with severity of Lewy body pathology independent of Alzheimer pathology. Neurology. 2018 Sep 18; 91(12):e1182-e1195. Epub 2018 Aug 24.
    View PubMed
  482. Knopman DS. The Telephone Interview for Cognitive Status. Cogn Behav Neurol. 2018 Sep; 31 (3):158
    View PubMed
  483. Wennberg AMV, Lesnick TG, Schwarz CG, Savica R, Hagen CE, Roberts RO, Knopman DS, Hollman JH, Vemuri P, Jack CR Jr, Petersen RC, Mielke MM. Longitudinal Association Between Brain Amyloid-Beta and Gait in the Mayo Clinic Study of Aging. J Gerontol A Biol Sci Med Sci. 2018 Aug 10; 73 (9):1244-1250
    View PubMed
  484. Schulte PJ, Roberts RO, Knopman DS, Petersen RC, Hanson AC, Schroeder DR, Weingarten TN, Martin DP, Warner DO, Sprung J. Association between exposure to anaesthesia and surgery and long-term cognitive trajectories in older adults: report from the Mayo Clinic Study of Aging. Br J Anaesth. 2018 Aug; 121 (2):398-405 Epub 2018 June 27
    View PubMed
  485. Palta P, Chen H, Deal JA, Sharrett AR, Gross A, Knopman D, Griswold M, Heiss G, Mosley TH. Olfactory function and neurocognitive outcomes in old age: The Atherosclerosis Risk in Communities Neurocognitive Study. Alzheimers Dement. 2018 Aug; 14 (8):1015-1021 Epub 2018 Mar 30
    View PubMed
  486. Mielke MM, Hagen CE, Xu J, Chai X, Vemuri P, Lowe VJ, Airey DC, Knopman DS, Roberts RO, Machulda MM, Jack CR Jr, Petersen RC, Dage JL. Plasma phospho-tau181 increases with Alzheimer's disease clinical severity and is associated with tau- and amyloid-positron emission tomography. Alzheimers Dement. 2018 Aug; 14 (8):989-997 Epub 2018 Apr 05
    View PubMed
  487. Roberts RO, Aakre JA, Kremers WK, Vassilaki M, Knopman DS, Mielke MM, Alhurani R, Geda YE, Machulda MM, Coloma P, Schauble B, Lowe VJ, Jack CR Jr, Petersen RC. Prevalence and Outcomes of Amyloid Positivity Among Persons Without Dementia in a Longitudinal, Population-Based Setting. JAMA Neurol. 2018 Aug 1; 75 (8):970-979
    View PubMed
  488. Walker KA, Windham BG, Power MC, Hoogeveen RC, Folsom AR, Ballantyne CM, Knopman DS, Selvin E, Jack CR Jr, Gottesman RF. The association of mid-to late-life systemic inflammation with white matter structure in older adults: The Atherosclerosis Risk in Communities Study. Neurobiol Aging. 2018 Aug; 68:26-33 Epub 2018 Apr 04
    View PubMed
  489. Whitwell JL, Graff-Radford J, Tosakulwong N, Weigand SD, Machulda MM, Senjem ML, Spychalla AJ, Vemuri P, Jones DT, Drubach DA, Knopman DS, Boeve BF, Ertekin-Taner N, Petersen RC, Lowe VJ, Jack CR Jr, Josephs KA. Imaging correlations of tau, amyloid, metabolism, and atrophy in typical and atypical Alzheimer's disease. Alzheimers Dement. 2018 Aug; 14 (8):1005-1014 Epub 2018 Mar 30
    View PubMed
  490. Wennberg AMV, Hagen CE, Edwards K, Roberts RO, Machulda MM, Knopman DS, Petersen RC, Mielke MM. Association of antidiabetic medication use, cognitive decline, and risk of cognitive impairment in older people with type 2 diabetes: Results from the population-based Mayo Clinic Study of Aging. Int J Geriatr Psychiatry. 2018 Aug; 33 (8):1114-1120 Epub 2018 June 05
    View PubMed
  491. van Harten AC, Mielke MM, Swenson-Dravis DM, Hagen CE, Edwards KK, Roberts RO, Geda YE, Knopman DS, Petersen RC. Subjective cognitive decline and risk of MCI: The Mayo Clinic Study of Aging. Neurology. 2018 Jul 24; 91 (4):e300-e312 Epub 2018 June 29
    View PubMed
  492. Botha H, Duffy JR, Whitwell JL, Strand EA, Machulda MM, Spychalla AJ, Tosakulwong N, Senjem ML, Knopman DS, Petersen RC, Jack CR Jr, Lowe VJ, Josephs KA. Non-right handed primary progressive apraxia of speech. J Neurol Sci. 2018 Jul 15; 390:246-254 Epub 2018 May 07
    View PubMed
  493. Wennberg AMV, Hagen CE, Machulda MM, Hollman JH, Roberts RO, Knopman DS, Petersen RC, Mielke MM. The association between peripheral total IGF-1, IGFBP-3, and IGF-1/IGFBP-3 and functional and cognitive outcomes in the Mayo Clinic Study of Aging. Neurobiol Aging. 2018 Jun; 66:68-74 Epub 2018 Feb 19
    View PubMed
  494. Carvalho DZ, St Louis EK, Knopman DS, Boeve BF, Lowe VJ, Roberts RO, Mielke MM, Przybelski SA, Machulda MM, Petersen RC, Jack CR Jr, Vemuri P. Association of Excessive Daytime Sleepiness With Longitudinal beta-Amyloid Accumulation in Elderly Persons Without Dementia. JAMA Neurol. 2018 Jun 1; 75 (6):672-680
    View PubMed
  495. Pottier C, Zhou X, Perkerson RB 3rd, Baker M, Jenkins GD, Serie DJ, Ghidoni R, Benussi L, Binetti G, Lopez de Munain A, Zulaica M, Moreno F, Le Ber I, Pasquier F, Hannequin D, Sanchez-Valle R, Antonell A, Llado A, Parsons TM, Finch NA, Finger EC, Lippa CF, Huey ED, Neumann M, Heutink P, Synofzik M, Wilke C, Rissman RA, Slawek J, Sitek E, Johannsen P, Nielsen JE, Ren Y, van Blitterswijk M, DeJesus-Hernandez M, Christopher E, Murray ME, Bieniek KF, Evers BM, Ferrari C, Rollinson S, Richardson A, Scarpini E, Fumagalli GG, Padovani A, Hardy J, Momeni P, Ferrari R, Frangipane F, Maletta R, Anfossi M, Gallo M, Petrucelli L, Suh E, Lopez OL, Wong TH, van Rooij JGJ, Seelaar H, Mead S, Caselli RJ, Reiman EM, Noel Sabbagh M, Kjolby M, Nykjaer A, Karydas AM, Boxer AL, Grinberg LT, Grafman J, Spina S, Oblak A, Mesulam MM, Weintraub S, Geula C, Hodges JR, Piguet O, Brooks WS, Irwin DJ, Trojanowski JQ, Lee EB, Josephs KA, Parisi JE, Ertekin-Taner N, Knopman DS, Nacmias B, Piaceri I, Bagnoli S, Sorbi S, Gearing M, Glass J, Beach TG, Black SE, Masellis M, Rogaeva E, Vonsattel JP, Honig LS, Kofler J, Bruni AC, Snowden J, Mann D, Pickering-Brown S, Diehl-Schmid J, Winkelmann J, Galimberti D, Graff C, Oijerstedt L, Troakes C, Al-Sarraj S, Cruchaga C, Cairns NJ, Rohrer JD, Halliday GM, Kwok JB, van Swieten JC, White CL 3rd, Ghetti B, Murell JR, Mackenzie IRA, Hsiung GR, Borroni B, Rossi G, Tagliavini F, Wszolek ZK, Petersen RC, Bigio EH, Grossman M, Van Deerlin VM, Seeley WW, Miller BL, Graff-Radford NR, Boeve BF, Dickson DW, Biernacka JM, Rademakers R. Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study. Lancet Neurol. 2018 Jun; 17 (6):548-558 Epub 2018 Apr 30
    View PubMed
  496. Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoumaki S, Giddaluru S, Gustavson DE, Hayward C, Hofer E, Ikram MA, Karlsson R, Knowles E, Lahti J, Leber M, Li S, Mather KA, Melle I, Morris D, Oldmeadow C, Palviainen T, Payton A, Pazoki R, Petrovic K, Reynolds CA, Sargurupremraj M, Scholz M, Smith JA, Smith AV, Terzikhan N, Thalamuthu A, Trompet S, van der Lee SJ, Ware EB, Windham BG, Wright MJ, Yang J, Yu J, Ames D, Amin N, Amouyel P, Andreassen OA, Armstrong NJ, Assareh AA, Attia JR, Attix D, Avramopoulos D, Bennett DA, Bohmer AC, Boyle PA, Brodaty H, Campbell H, Cannon TD, Cirulli ET, Congdon E, Conley ED, Corley J, Cox SR, Dale AM, Dehghan A, Dick D, Dickinson D, Eriksson JG, Evangelou E, Faul JD, Ford I, Freimer NA, Gao H, Giegling I, Gillespie NA, Gordon SD, Gottesman RF, Griswold ME, Gudnason V, Harris TB, Hartmann AM, Hatzimanolis A, Heiss G, Holliday EG, Joshi PK, Kahonen M, Kardia SLR, Karlsson I, Kleineidam L, Knopman DS, Kochan NA, Konte B, Kwok JB, Le Hellard S, Lee T, Lehtimaki T, Li SC, Lill CM, Liu T, Koini M, London E, Longstreth WT Jr, Lopez OL, Loukola A, Luck T, Lundervold AJ, Lundquist A, Lyytikainen LP, Martin NG, Montgomery GW, Murray AD, Need AC, Noordam R, Nyberg L, Ollier W, Papenberg G, Pattie A, Polasek O, Poldrack RA, Psaty BM, Reppermund S, Riedel-Heller SG, Rose RJ, Rotter JI, Roussos P, Rovio SP, Saba Y, Sabb FW, Sachdev PS, Satizabal CL, Schmid M, Scott RJ, Scult MA, Simino J, Slagboom PE, Smyrnis N, Soumare A, Stefanis NC, Stott DJ, Straub RE, Sundet K, Taylor AM, Taylor KD, Tzoulaki I, Tzourio C, Uitterlinden A, Vitart V, Voineskos AN, Kaprio J, Wagner M, Wagner H, Weinhold L, Wen KH, Widen E, Yang Q, Zhao W, Adams HHH, Arking DE, Bilder RM, Bitsios P, Boerwinkle E, Chiba-Falek O, Corvin A, De Jager PL, Debette S, Donohoe G, Elliott P, Fitzpatrick AL, Gill M, Glahn DC, Hagg S, Hansell NK, Hariri AR, Ikram MK, Jukema JW, Vuoksimaa E, Keller MC, Kremen WS, Launer L, Lindenberger U, Palotie A, Pedersen NL, Pendleton N, Porteous DJ, Raikkonen K, Raitakari OT, Ramirez A, Reinvang I, Rudan I, Dan Rujescu Rujescu, Schmidt R, Schmidt H, Schofield PW, Schofield PR, Starr JM, Steen VM, Trollor JN, Turner ST, Van Duijn CM, Villringer A, Weinberger DR, Weir DR, Wilson JF, Malhotra A, McIntosh AM, Gale CR, Seshadri S, Mosley TH Jr, Bressler J, Lencz T, Deary IJ. Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. Nat Commun. 2018 May 29; 9 (1):2098
    View PubMed
  497. Gonzalez HM, Tarraf W, Harrison K, Windham BG, Tingle J, Alonso A, Griswold M, Heiss G, Knopman D, Mosley TH. Midlife cardiovascular health and 20-year cognitive decline: Atherosclerosis Risk in Communities Study results. Alzheimers Dement. 2018 May; 14 (5):579-589 Epub 2017 Dec 18
    View PubMed
  498. Ali F, Whitwell JL, Martin PR, Senjem ML, Knopman DS, Jack CR, Lowe VJ, Petersen RC, Boeve BF, Josephs KA. [(18)F] AV-1451 uptake in corticobasal syndrome: the influence of beta-amyloid and clinical presentation. J Neurol. 2018 May; 265 (5):1079-1088 Epub 2018 Mar 01
    View PubMed
  499. Jack CR Jr, Wiste HJ, Schwarz CG, Lowe VJ, Senjem ML, Vemuri P, Weigand SD, Therneau TM, Knopman DS, Gunter JL, Jones DT, Graff-Radford J, Kantarci K, Roberts RO, Mielke MM, Machulda MM, Petersen RC. Longitudinal tau PET in ageing and Alzheimer's disease. Brain. 2018 May 1; 141 (5):1517-1528
    View PubMed
  500. Zeydan B, Lowe VJ, Schwarz CG, Przybelski SA, Tosakulwong N, Zuk SM, Senjem ML, Gunter JL, Roberts RO, Mielke MM, Benarroch EE, Rodriguez M, Machulda MM, Lesnick TG, Knopman DS, Petersen RC, Jack CR Jr, Kantarci K, Kantarci OH. Pittsburgh compound-B PET white matter imaging and cognitive function in late multiple sclerosis. Mult Scler. 2018 May; 24 (6):739-749 Epub 2017 May 05
    View PubMed
  501. Knopman DS, Lundt ES, Therneau TM, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, Petersen RC, Jack CR Jr. Joint associations of beta-amyloidosis and cortical thickness with cognition. Neurobiol Aging. 2018 May; 65:121-131 Epub 2018 Feb 02
    View PubMed
  502. Hughes TM, Wagenknecht LE, Craft S, Mintz A, Heiss G, Palta P, Wong D, Zhou Y, Knopman D, Mosley TH, Gottesman RF. Arterial stiffness and dementia pathology: Atherosclerosis Risk in Communities (ARIC)-PET Study. Neurology. 2018 Apr 3; 90 (14):e1248-e1256 Epub 2018 Mar 16
    View PubMed
  503. Botha H, Mantyh WG, Murray ME, Knopman DS, Przybelski SA, Wiste HJ, Graff-Radford J, Josephs KA, Schwarz CG, Kremers WK, Boeve BF, Petersen RC, Machulda MM, Parisi JE, Dickson DW, Lowe V, Jack CR Jr, Jones DT. FDG-PET in tau-negative amnestic dementia resembles that of autopsy-proven hippocampal sclerosis. Brain. 2018 Apr 1; 141 (4):1201-1217
    View PubMed
  504. Knopman DS, Haeberlein SB, Carrillo MC, Hendrix JA, Kerchner G, Margolin R, Maruff P, Miller DS, Tong G, Tome MB, Murray ME, Nelson PT, Sano M, Mattsson N, Sultzer DL, Montine TJ, Jack CR Jr, Kolb H, Petersen RC, Vemuri P, Canniere MZ, Schneider JA, Resnick SM, Romano G, van Harten AC, Wolk DA, Bain LJ, Siemers E. The National Institute on Aging and the Alzheimer's Association Research Framework for Alzheimer's disease: Perspectives from the Research Roundtable. Alzheimers Dement. 2018 Apr; 14 (4):563-575
    View PubMed
  505. Klinger RY, James OG, Borges-Neto S, Bisanar T, Li YJ, Qi W, Berger M, Terrando N, Newman MF, Doraiswamy PM, Mathew JP, Alzheimer's Disease Neuroimaging Initiative (ADNI) Study Group//Neurologic Outcomes Research Group (NORG). 18F-florbetapir Positron Emission Tomography-determined Cerebral beta-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery. Anesthesiology. 2018 Apr; 128 (4):728-744
    View PubMed
  506. Deal JA, Sharrett AR, Rawlings AM, Gottesman RF, Bandeen-Roche K, Albert M, Knopman D, Selvin E, Wasserman BA, Klein B, Klein R. Retinal signs and 20-year cognitive decline in the Atherosclerosis Risk in Communities Study. Neurology. 2018 Mar 27; 90 (13):e1158-e1166 Epub 2018 Feb 28
    View PubMed
  507. Botha H, Mantyh WG, Graff-Radford J, Machulda MM, Przybelski SA, Wiste HJ, Senjem ML, Parisi JE, Petersen RC, Murray ME, Boeve BF, Lowe VJ, Knopman DS, Jack CR Jr, Jones DT. Tau-negative amnestic dementia masquerading as Alzheimer disease dementia. Neurology. 2018 Mar 13; 90 (11):e940-e946 Epub 2018 Feb 07
    View PubMed
  508. Jones DT, Knopman DS, Graff-Radford J, Syrjanen JA, Senjem ML, Schwarz CG, Dheel C, Wszolek Z, Rademakers R, Kantarci K, Petersen RC, Jack CR Jr, Lowe VJ, Boeve BF. In vivo (18)F-AV-1451 tau PET signal in MAPT mutation carriers varies by expected tau isoforms. Neurology. 2018 Mar 13; 90 (11):e947-e954 Epub 2018 Feb 09
    View PubMed
  509. Burns CM, Knopman DS, Tupper DE, Davey CS, Slinin YM, Lakshminarayan K, Rossom RC, Pederson SL, Gilbertson DT, Murray AM. Prevalence and Risk of Severe Cognitive Impairment in Advanced Chronic Kidney Disease. J Gerontol A Biol Sci Med Sci. 2018 Mar 2; 73 (3):393-399
    View PubMed
  510. Jung Y, Jordan LG 3rd, Lowe VJ, Kantarci K, Parisi JE, Dickson DW, Murray ME, Reichard RR, Ferman TJ, Jones DT, Graff-Radford J, Savica R, Machulda MM, Fields JA, Allen LA, Drubach DA, St Louis EK, Silber MH, Jack CR Jr, Knopman DS, Petersen RC, Boeve BF. Clinicopathological and 123I-FP-CIT SPECT correlations in patients with dementia. Ann Clin Transl Neurol. 2018 Mar; 5(3):376-381. Epub 2018 Jan 24.
    View PubMed
  511. Josephs KA, Martin PR, Botha H, Schwarz CG, Duffy JR, Clark HM, Machulda MM, Graff-Radford J, Weigand SD, Senjem ML, Utianski RL, Drubach DA, Boeve BF, Jones DT, Knopman DS, Petersen RC, Jack CR Jr, Lowe VJ, Whitwell JL. [(18) F]AV-1451 tau-PET and primary progressive aphasia. Ann Neurol. 2018 Mar; 83 (3):599-611 Epub 2018 Mar 13
    View PubMed
  512. Arnold Fiebelkorn C, Vemuri P, Rabinstein AA, Mielke MM, Przybelski SA, Kantarci K, Jones DT, Brown RD Jr, Knopman DS, Petersen RC, Jack CR Jr, Graff-Radford J. Frequency of Acute and Subacute Infarcts in a Population-Based Study. Mayo Clin Proc. 2018 Mar; 93 (3):300-306 Epub 2018 Feb 14
    View PubMed
  513. Fatemi F, Kantarci K, Graff-Radford J, Preboske GM, Weigand SD, Przybelski SA, Knopman DS, Machulda MM, Roberts RO, Mielke MM, Petersen RC, Jack CR Jr, Vemuri P. Sex differences in cerebrovascular pathologies on FLAIR in cognitively unimpaired elderly. Neurology. 2018 Feb 6; 90 (6):e466-e473 Epub 2018 Jan 17
    View PubMed
  514. Krell-Roesch J, Lowe VJ, Neureiter J, Pink A, Roberts RO, Mielke MM, Vemuri P, Stokin GB, Christianson TJ, Jack CR, Knopman DS, Boeve BF, Kremers WK, Petersen RC, Geda YE. Depressive and anxiety symptoms and cortical amyloid deposition among cognitively normal elderly persons: the Mayo Clinic Study of Aging. Int Psychogeriatr. 2018 Feb; 30 (2):245-251 Epub 2017 Dec 04
    View PubMed
  515. Graff-Radford J, Raman MR, Rabinstein AA, Przybelski SA, Lesnick TG, Boeve BF, Murray ME, Dickson DW, Reichard RR, Parisi JE, Knopman DS, Petersen RC, Jack CR Jr, Kantarci K. Association Between Microinfarcts and Blood Pressure Trajectories. JAMA Neurol. 2018 Feb 1; 75 (2):212-218
    View PubMed
  516. Power MC, Rawlings A, Sharrett AR, Bandeen-Roche K, Coresh J, Ballantyne CM, Pokharel Y, Michos ED, Penman A, Alonso A, Knopman D, Mosley TH, Gottesman RF. Association of midlife lipids with 20-year cognitive change: A cohort study. Alzheimers Dement. 2018 Feb; 14 (2):167-177 Epub 2017 Sept 12
    View PubMed
  517. Knopman DS, Siemers ER, Bain LJ, Hendrix JA, Carrillo MC. National Institute on Aging - Alzheimer's Association Research Framework lays the groundwork for deeper understanding of Alzheimer's disease. Alzheimers Dement. 2018 Feb; 14 (2):261-262
    View PubMed
  518. Whitwell JL, Graff-Radford J, Tosakulwong N, Weigand SD, Machulda M, Senjem ML, Schwarz CG, Spychalla AJ, Jones DT, Drubach DA, Knopman DS, Boeve BF, Ertekin-Taner N, Petersen RC, Lowe VJ, Jack CR Jr, Josephs KA. [(18) F]AV-1451 clustering of entorhinal and cortical uptake in Alzheimer's disease. Ann Neurol. 2018 Feb; 83 (2):248-257 Epub 2018 Feb 06
    View PubMed
  519. Lutsey PL, Misialek JR, Mosley TH, Gottesman RF, Punjabi NM, Shahar E, MacLehose R, Ogilvie RP, Knopman D, Alonso A. Sleep characteristics and risk of dementia and Alzheimer's disease: The Atherosclerosis Risk in Communities Study. Alzheimers Dement. 2018 Feb; 14 (2):157-166 Epub 2017 July 21
    View PubMed
  520. Evered L, Silbert B, Knopman DS, Scott DA, DeKosky ST, Rasmussen LS, Oh ES, Crosby G, Berger M, Eckenhoff RG, Nomenclature Consensus Working Group. Recommendations for the Nomenclature of Cognitive Change Associated with Anaesthesia and Surgery-20181. J Alzheimers Dis. 2018; 66 (1):1-10
    View PubMed
  521. Walker KA, Windham BG, Brown CH, Knopman DS, Jack CR, Mosley TH, Selvin E, Wong DF, Hughes TM, Zhou Y, Gross AL, Gottesman RF. The Association of Mid- and Late-Life Systemic Inflammation with Brain Amyloid Deposition: The ARIC-PET Study. J Alzheimers Dis. 2018; 66 (3):1041-1052
    View PubMed
  522. Ramanan VK, Przybelski SA, Graff-Radford J, Castillo AM, Lowe VJ, Mielke MM, Roberts RO, Reid RI, Knopman DS, Jack CR, Petersen RC, Vemuri P. Statins and Brain Health: Alzheimer's Disease and Cerebrovascular Disease Biomarkers in Older Adults. J Alzheimers Dis. 2018; 65 (4):1345-1352
    View PubMed
  523. Schneider ALC, Zhao D, Lutsey PL, Gottesman RF, Sharrett AR, Rawlings AM, Alonso A, Knopman D, Mosley TH, Selvin E, Michos ED. Serum Vitamin D Concentrations and Cognitive Change Over 20 Years: The Atherosclerosis Risk in Communities Neurocognitive Study. Neuroepidemiology. 2018; 51 (3-4):131-137 Epub 2018 Aug 09
    View PubMed
  524. Weintraub S, Carrillo MC, Farias ST, Goldberg TE, Hendrix JA, Jaeger J, Knopman DS, Langbaum JB, Park DC, Ropacki MT, Sikkes SAM, Welsh-Bohmer KA, Bain LJ, Brashear R, Budur K, Graf A, Martenyi F, Storck MS, Randolph C. Measuring cognition and function in the preclinical stage of Alzheimer's disease. Alzheimers Dement (N Y). 2018; 4:64-75 Epub 2018 Feb 13
    View PubMed
  525. Nedelska Z, Senjem ML, Przybelski SA, Lesnick TG, Lowe VJ, Boeve BF, Arani A, Vemuri P, Graff-Radford J, Ferman TJ, Jones DT, Savica R, Knopman DS, Petersen RC, Jack CR, Kantarci K. Regional cortical perfusion on arterial spin labeling MRI in dementia with Lewy bodies: Associations with clinical severity, glucose metabolism and tau PET. Neuroimage Clin. 2018; 19:939-947 Epub 2018 June 19
    View PubMed
  526. Krell-Roesch J, Feder NT, Roberts RO, Mielke MM, Christianson TJ, Knopman DS, Petersen RC, Geda YE. Leisure-Time Physical Activity and the Risk of Incident Dementia: The Mayo Clinic Study of Aging. J Alzheimers Dis. 2018; 63 (1):149-155
    View PubMed
  527. Lowe VJ, Bruinsma TJ, Min HK, Lundt ES, Fang P, Senjem ML, Boeve BF, Josephs KA, Pandey MK, Murray ME, Kantarci K, Jones DT, Schwarz CG, Knopman DS, Petersen RC, Jack CR Jr. Elevated medial temporal lobe and pervasive brain tau-PET signal in normal participants. Alzheimers Dement (Amst). 2018; 10:210-216 Epub 2018 Feb 07
    View PubMed
  528. Johnson DR, Hunt CH, Nathan MA, Parisi JE, Boeve BF, Murray ME, Knopman DS, Jack CR Jr, Petersen RC, Lowe VJ, Johnson GB. Pittsburgh compound B (PiB) PET imaging of meningioma and other intracranial tumors. J Neurooncol. 2018 Jan; 136 (2):373-378 Epub 2017 Nov 08
    View PubMed
  529. Lowe VJ, Wiste HJ, Senjem ML, Weigand SD, Therneau TM, Boeve BF, Josephs KA, Fang P, Pandey MK, Murray ME, Kantarci K, Jones DT, Vemuri P, Graff-Radford J, Schwarz CG, Machulda MM, Mielke MM, Roberts RO, Knopman DS, Petersen RC, Jack CR Jr. Widespread brain tau and its association with ageing, Braak stage and Alzheimer's dementia. Brain. 2018 Jan 1; 141 (1):271-287
    View PubMed
  530. Kirk L, Smith GE, Gaugler JE, Hepburn K, Knopman D, Lewis M. Development and Testing of a Neuropsychiatric Symptoms Model in Mild Cognitive Impairment. J Gerontol Nurs. 2018 Jan 1; 44 (1):21-30 Epub 2017 Sept 12
    View PubMed
  531. Botha H, Utianski RL, Whitwell JL, Duffy JR, Clark HM, Strand EA, Machulda MM, Tosakulwong N, Knopman DS, Petersen RC, Jack CR Jr, Josephs KA, Jones DT. Disrupted functional connectivity in primary progressive apraxia of speech. Neuroimage Clin. 2018; 18:617-629 Epub 2018 Mar 03
    View PubMed
  532. Vassilaki M, Aakre JA, Syrjanen JA, Mielke MM, Geda YE, Kremers WK, Machulda MM, Alhurani RE, Staubo SC, Knopman DS, Petersen RC, Lowe VJ, Jack CR, Roberts RO. Mediterranean Diet, Its Components, and Amyloid Imaging Biomarkers. J Alzheimers Dis. 2018; 64 (1):281-290
    View PubMed
  533. Townley RA, Botha H, Graff-Radford J, Boeve BF, Petersen RC, Senjem ML, Knopman DS, Lowe V, Jack CR Jr, Jones DT. (18)F-FDG PET-CT pattern in idiopathic normal pressure hydrocephalus. Neuroimage Clin. 2018; 18:897-902 Epub 2018 Feb 28
    View PubMed
  534. Sahoo A, Bejanin A, Murray ME, Tosakulwong N, Weigand SD, Serie AM, Senjem ML, Machulda MM, Parisi JE, Boeve BF, Knopman DS, Petersen RC, Dickson DW, Whitwell JL, Josephs KA. TDP-43 and Alzheimer's Disease Pathologic Subtype in Non-Amnestic Alzheimer's Disease Dementia. J Alzheimers Dis. 2018; 64 (4):1227-1233
    View PubMed
  535. Corriveau RA, Koroshetz WJ, Gladman JT, Jeon S, Babcock D, Bennett DA, Carmichael ST, Dickinson SL, Dickson DW, Emr M, Fillit H, Greenberg SM, Hutton ML, Knopman DS, Manly JJ, Marder KS, Moy CS, Phelps CH, Scott PA, Seeley WW, Sieber BA, Silverberg NB, Sutherland ML, Taylor A, Torborg CL, Waddy SP, Gubitz AK, Holtzman DM. Alzheimer's Disease-Related Dementias Summit 2016: National research priorities. Neurology. 2017 Dec 5; 89 (23):2381-2391 Epub 2017 Nov 08
    View PubMed
  536. Pink A, Przybelski SA, Krell-Roesch J, Stokin GB, Roberts RO, Mielke MM, Spangehl KA, Knopman DS, Jack CR Jr, Petersen RC, Geda YE. Cortical Thickness and Anxiety Symptoms Among Cognitively Normal Elderly Persons: The Mayo Clinic Study of Aging. J Neuropsychiatry Clin Neurosci. 2017 Winter; 29 (1):60-66 Epub 2016 Aug 31
    View PubMed
  537. Botha H, Finch NA, Gavrilova RH, Machulda MM, Fields JA, Lowe VJ, Petersen RC, Jack CR Jr, Dheel CM, Gearhart DJ, Knopman DS, Rademakers R, Boeve BF. Novel GRN mutation presenting as an aphasic dementia and evolving into corticobasal syndrome. Neurol Genet. 2017 Dec; 3 (6):e201 Epub 2017 Dec 11
    View PubMed
  538. Pichler M, Vemuri P, Rabinstein AA, Aakre J, Flemming KD, Brown RD Jr, Kumar N, Kantarci K, Kremers W, Mielke MM, Knopman DS, Jack CR Jr, Petersen RC, Lowe V, Graff-Radford J. Prevalence and Natural History of Superficial Siderosis: A Population-Based Study. Stroke. 2017 Dec; 48 (12):3210-3214 Epub 2017 Oct 25
    View PubMed
  539. Walker KA, Power MC, Hoogeveen RC, Folsom AR, Ballantyne CM, Knopman DS, Windham BG, Selvin E, Jack CR Jr, Gottesman RF. Midlife Systemic Inflammation, Late-Life White Matter Integrity, and Cerebral Small Vessel Disease: The Atherosclerosis Risk in Communities Study. Stroke. 2017 Dec; 48 (12):3196-3202 Epub 2017 Nov 03
    View PubMed
  540. Jones DT, Graff-Radford J, Lowe VJ, Wiste HJ, Gunter JL, Senjem ML, Botha H, Kantarci K, Boeve BF, Knopman DS, Petersen RC, Jack CR Jr. Tau, amyloid, and cascading network failure across the Alzheimer's disease spectrum. Cortex. 2017 Dec; 97:143-159 Epub 2017 Oct 03
    View PubMed
  541. Bruinsma TJ, Johnson DR, Fang P, Senjem M, Josephs KA, Whitwell JL, Boeve BF, Pandey MK, Kantarci K, Jones DT, Vemuri P, Murray M, Graff-Radford J, Schwarz CG, Knopman DS, Petersen RC, Jack CR Jr, Lowe VJ. Uptake of AV-1451 in meningiomas. Ann Nucl Med. 2017 Dec; 31 (10):736-743 Epub 2017 Sept 08
    View PubMed
  542. Walker KA, Hoogeveen RC, Folsom AR, Ballantyne CM, Knopman DS, Windham BG, Jack CR Jr, Gottesman RF. Midlife systemic inflammatory markers are associated with late-life brain volume: The ARIC study. Neurology. 2017 Nov 28; 89 (22):2262-2270 Epub 2017 Nov 01
    View PubMed
  543. Roberts RO, Knopman DS, Syrjanen JA, Aakre JA, Vassilaki M, Kremers WK, Mielke MM, Machulda MM, Graff-Radford J, Geda YE, Vemuri P, Lowe V, Jack CR Jr, Petersen RC. Weighting and standardization of frequencies to determine prevalence of AD imaging biomarkers. Neurology. 2017 Nov 14; 89 (20):2039-2048 Epub 2017 Oct 13
    View PubMed
  544. Graff-Radford J, Simino J, Kantarci K, Mosley TH Jr, Griswold ME, Windham BG, Sharrett AR, Albert MS, Gottesman RF, Jack CR Jr, Vemuri P, Knopman DS. Neuroimaging Correlates of Cerebral Microbleeds: The ARIC Study (Atherosclerosis Risk in Communities). Stroke. 2017 Nov; 48 (11):2964-2972 Epub 2017 Oct 10
    View PubMed
  545. Vemuri P, Lesnick TG, Przybelski SA, Knopman DS, Lowe VJ, Graff-Radford J, Roberts RO, Mielke MM, Machulda MM, Petersen RC, Jack CR Jr. Age, vascular health, and Alzheimer disease biomarkers in an elderly sample. Ann Neurol. 2017 Nov; 82 (5):706-718 Epub 2017 Oct 26
    View PubMed
  546. Schneider ALC, Selvin E, Sharrett AR, Griswold M, Coresh J, Jack CR Jr, Knopman D, Mosley T, Gottesman RF. Diabetes, Prediabetes, and Brain Volumes and Subclinical Cerebrovascular Disease on MRI: The Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS). Diabetes Care. 2017 Nov; 40 (11):1514-1521 Epub 2017 Sept 15
    View PubMed
  547. Josephs KA, Dickson DW, Tosakulwong N, Weigand SD, Murray ME, Petrucelli L, Liesinger AM, Senjem ML, Spychalla AJ, Knopman DS, Parisi JE, Petersen RC, Jack CR Jr, Whitwell JL. Rates of hippocampal atrophy and presence of post-mortem TDP-43 in patients with Alzheimer's disease: a longitudinal retrospective study. Lancet Neurol. 2017 Nov; 16 (11):917-924 Epub 2017 Sept 11
    View PubMed
  548. Zeydan B, Deelchand DK, Tosakulwong N, Lesnick TG, Kantarci OH, Machulda MM, Knopman DS, Lowe VJ, Jack CR Jr, Petersen RC, Oz G, Kantarci K. Decreased Glutamate Levels in Patients with Amnestic Mild Cognitive Impairment: An sLASER Proton MR Spectroscopy and PiB-PET Study. J Neuroimaging. 2017 Nov; 27 (6):630-636 Epub 2017 June 29
    View PubMed
  549. Yano Y, Butler KR, Hall ME, Schwartz GL, Knopman DS, Lirette ST, Jones DW, Wilson JG, Hall JE, Correa A, Turner ST, Mosley TH. Associations of Nocturnal Blood Pressure With Cognition by Self-Identified Race in Middle-Aged and Older Adults: The GENOA (Genetic Epidemiology Network of Arteriopathy) Study. J Am Heart Assoc. 2017 Oct 27; 6 (11)
    View PubMed
  550. Lee JS, Jung NY, Jang YK, Kim HJ, Seo SW, Lee J, Kim YJ, Lee JH, Kim BC, Park KW, Yoon SJ, Jeong JH, Kim SY, Kim SH, Kim EJ, Park KC, Knopman DS, Na DL. Erratum to: Prognosis of Patients with Behavioral Variant Frontotemporal Dementia Who have Focal Versus Diffuse Frontal Atrophy. J Clin Neurol. 2017 Oct; 13 (4):447
    View PubMed
  551. Gottesman RF, Albert MS, Alonso A, Coker LH, Coresh J, Davis SM, Deal JA, McKhann GM, Mosley TH, Sharrett AR, Schneider ALC, Windham BG, Wruck LM, Knopman DS. Associations Between Midlife Vascular Risk Factors and 25-Year Incident Dementia in the Atherosclerosis Risk in Communities (ARIC) Cohort. JAMA Neurol. 2017 Oct 1; 74 (10):1246-1254
    View PubMed
  552. Nedelska Z, Przybelski SA, Lesnick TG, Schwarz CG, Lowe VJ, Machulda MM, Kremers WK, Mielke MM, Roberts RO, Boeve BF, Knopman DS, Petersen RC, Jack CR Jr, Kantarci K. (1)H-MRS metabolites and rate of beta-amyloid accumulation on serial PET in clinically normal adults. Neurology. 2017 Sep 26; 89 (13):1391-1399 Epub 2017 Aug 25
    View PubMed
  553. Mioshi E, Flanagan E, Knopman D. Detecting clinical change with the CDR-FTLD: differences between FTLD and AD dementia. Int J Geriatr Psychiatry. 2017 Sep; 32 (9):977-982 Epub 2016 July 28
    View PubMed
  554. Mielke MM, Hagen CE, Wennberg AMV, Airey DC, Savica R, Knopman DS, Machulda MM, Roberts RO, Jack CR Jr, Petersen RC, Dage JL. Association of Plasma Total Tau Level With Cognitive Decline and Risk of Mild Cognitive Impairment or Dementia in the Mayo Clinic Study on Aging. JAMA Neurol. 2017 Sep 1; 74 (9):1073-1080
    View PubMed
  555. Knopman D, Alford E, Tate K, Long M, Khachaturian AS. Patients come from populations and populations contain patients. A two-stage scientific and ethics review: The next adaptation for single institutional review boards. Alzheimers Dement. 2017 Aug; 13 (8):940-946 Epub 2017 July 11
    View PubMed
  556. Sprung J, Roberts RO, Weingarten TN, Nunes Cavalcante A, Knopman DS, Petersen RC, Hanson AC, Schroeder DR, Warner DO. Postoperative delirium in elderly patients is associated with subsequent cognitive impairment. Br J Anaesth. 2017 Aug 1; 119 (2):316-323
    View PubMed
  557. Finch NA, Wang X, Baker MC, Heckman MG, Gendron TF, Bieniek KF, Wuu J, DeJesus-Hernandez M, Brown PH, Chew J, Jansen-West KR, Daughrity LM, Nicholson AM, Murray ME, Josephs KA, Parisi JE, Knopman DS, Petersen RC, Petrucelli L, Boeve BF, Graff-Radford NR, Asmann YW, Dickson DW, Benatar M, Bowser R, Boylan KB, Rademakers R, van Blitterswijk M. Abnormal expression of homeobox genes and transthyretin in C9ORF72 expansion carriers. Neurol Genet. 2017 Aug; 3 (4):e161 Epub 2017 June 07
    View PubMed
  558. DeJesus-Hernandez M, Finch NA, Wang X, Gendron TF, Bieniek KF, Heckman MG, Vasilevich A, Murray ME, Rousseau L, Weesner R, Lucido A, Parsons M, Chew J, Josephs KA, Parisi JE, Knopman DS, Petersen RC, Boeve BF, Graff-Radford NR, de Boer J, Asmann YW, Petrucelli L, Boylan KB, Dickson DW, van Blitterswijk M, Rademakers R. In-depth clinico-pathological examination of RNA foci in a large cohort of C9ORF72 expansion carriers. Acta Neuropathol. 2017 Aug; 134 (2):255-269 Epub 2017 May 15
    View PubMed
  559. Kantarci K, Murray ME, Schwarz CG, Reid RI, Przybelski SA, Lesnick T, Zuk SM, Raman MR, Senjem ML, Gunter JL, Boeve BF, Knopman DS, Parisi JE, Petersen RC, Jack CR Jr, Dickson DW. White-matter integrity on DTI and the pathologic staging of Alzheimer's disease. Neurobiol Aging. 2017 Aug; 56:172-179 Epub 2017 May 04
    View PubMed
  560. Alonso A, Knopman DS, Gottesman RF, Soliman EZ, Shah AJ, O'Neal WT, Norby FL, Mosley TH, Chen LY. Correlates of Dementia and Mild Cognitive Impairment in Patients With Atrial Fibrillation: The Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS). J Am Heart Assoc. 2017 Jul 24; 6 (7) Epub 2017 July 24
    View PubMed
  561. Bressler J, Yu B, Mosley TH, Knopman DS, Gottesman RF, Alonso A, Sharrett AR, Wruck LM, Boerwinkle E. Metabolomics and cognition in African American adults in midlife: the atherosclerosis risk in communities study. Transl Psychiatry. 2017 Jul 18; 7 (7):e1173 Epub 2017 July 18
    View PubMed
  562. Ben-Avraham D, Karasik D, Verghese J, Lunetta KL, Smith JA, Eicher JD, Vered R, Deelen J, Arnold AM, Buchman AS, Tanaka T, Faul JD, Nethander M, Fornage M, Adams HH, Matteini AM, Callisaya ML, Smith AV, Yu L, De Jager PL, Evans DA, Gudnason V, Hofman A, Pattie A, Corley J, Launer LJ, Knopman DS, Parimi N, Turner ST, Bandinelli S, Beekman M, Gutman D, Sharvit L, Mooijaart SP, Liewald DC, Houwing-Duistermaat JJ, Ohlsson C, Moed M, Verlinden VJ, Mellstrom D, van der Geest JN, Karlsson M, Hernandez D, McWhirter R, Liu Y, Thomson R, Tranah GJ, Uitterlinden AG, Weir DR, Zhao W, Starr JM, Johnson AD, Ikram MA, Bennett DA, Cummings SR, Deary IJ, Harris TB, Kardia SLR, Mosley TH, Srikanth VK, Windham BG, Newman AB, Walston JD, Davies G, Evans DS, Slagboom EP, Ferrucci L, Kiel DP, Murabito JM, Atzmon G. Correction: The complex genetics of gait speed: genome-wide meta-analysis approach. Aging (Albany NY). 2017 Jul; 9 (7):1844-1846 Epub 2017 July 07
    View PubMed
  563. Lee JS, Jung NY, Jang YK, Kim HJ, Seo SW, Lee J, Kim YJ, Lee JH, Kim BC, Park KW, Yoon SJ, Jeong JH, Kim SY, Kim SH, Kim EJ, Park KC, Knopman DS, Na DL. Prognosis of Patients with Behavioral Variant Frontotemporal Dementia Who have Focal Versus Diffuse Frontal Atrophy. J Clin Neurol. 2017 Jul; 13 (3):234-242
    View PubMed
  564. Ben-Avraham D, Karasik D, Verghese J, Lunetta KL, Smith JA, Eicher JD, Vered R, Deelen J, Arnold AM, Buchman AS, Tanaka T, Faul JD, Nethander M, Fornage M, Adams HH, Matteini AM, Callisaya ML, Smith AV, Yu L, De Jager PL, Evans DA, Gudnason V, Hofman A, Pattie A, Corley J, Launer LJ, Knopman DS, Parimi N, Turner ST, Bandinelli S, Beekman M, Gutman D, Sharvit L, Mooijaart SP, Liewald DC, Houwing-Duistermaat JJ, Ohlsson C, Moed M, Verlinden VJ, Mellstrom D, van der Geest JN, Karlsson M, Hernandez D, McWhirter R, Liu YM, Thomson R, Tranah GJ, Uitterlinden AG, Weir DR, Zhao W, Starr JM, Johnson AD, Ikram MA, Bennett DA, Cummings SR, Deary IJ, Harris TB, Kardia SLR, Mosley TH, Srikanth VK, Windham BG, Newman AB, Walston JD, Davies G, Evans DS, Slagboom EP, Ferrucci L, Kiel DP, Murabito JM, Atzmon G. The complex genetics of gait speed: genome-wide meta-analysis approach (vol 9, pg 209, 2017) Aging-us. 2017 Jul; 9 (7):1844-6
  565. Schwarz CG, Jones DT, Gunter JL, Lowe VJ, Vemuri P, Senjem ML, Petersen RC, Knopman DS, Jack CR Jr, Alzheimer's Disease Neuroimaging Initiative. Contributions of imprecision in PET-MRI rigid registration to imprecision in amyloid PET SUVR measurements. Hum Brain Mapp. 2017 Jul; 38 (7):3323-3336 Epub 2017 Apr 22
    View PubMed
  566. Flemming KD, Graff-Radford J, Aakre J, Kantarci K, Lanzino G, Brown RD Jr, Mielke MM, Roberts RO, Kremers W, Knopman DS, Petersen RC, Jack CR Jr. Population-Based Prevalence of Cerebral Cavernous Malformations in Older Adults: Mayo Clinic Study of Aging. JAMA Neurol. 2017 Jul 1; 74 (7):801-805
    View PubMed
  567. Vemuri P, Knopman DS, Lesnick TG, Przybelski SA, Mielke MM, Graff-Radford J, Murray ME, Roberts RO, Vassilaki M, Lowe VJ, Machulda MM, Jones DT, Petersen RC, Jack CR Jr. Evaluation of Amyloid Protective Factors and Alzheimer Disease Neurodegeneration Protective Factors in Elderly Individuals. JAMA Neurol. 2017 Jun 1; 74 (6):718-726
    View PubMed
  568. Jack CR Jr, Wiste HJ, Weigand SD, Therneau TM, Knopman DS, Lowe V, Vemuri P, Mielke MM, Roberts RO, Machulda MM, Senjem ML, Gunter JL, Rocca WA, Petersen RC. Age-specific and sex-specific prevalence of cerebral beta-amyloidosis, tauopathy, and neurodegeneration in cognitively unimpaired individuals aged 50-95 years: a cross-sectional study. Lancet Neurol. 2017 Jun; 16 (6):435-444 Epub 2017 Apr 26
    View PubMed
  569. Vassilaki M, Christianson TJ, Mielke MM, Geda YE, Kremers WK, Machulda MM, Knopman DS, Petersen RC, Lowe VJ, Jack CR Jr, Roberts RO. Neuroimaging biomarkers and impaired olfaction in cognitively normal individuals. Ann Neurol. 2017 Jun; 81 (6):871-882 Epub 2017 June 09
    View PubMed
  570. Caselli RJ, Beach TG, Knopman DS, Graff-Radford NR. Alzheimer Disease: Scientific Breakthroughs and Translational Challenges. Mayo Clin Proc. 2017 Jun; 92 (6):978-994
    View PubMed
  571. Power MC, Tingle JV, Reid RI, Huang J, Sharrett AR, Coresh J, Griswold M, Kantarci K, Jack CR Jr, Knopman D, Gottesman RF, Mosley TH. Midlife and Late-Life Vascular Risk Factors and White Matter Microstructural Integrity: The Atherosclerosis Risk in Communities Neurocognitive Study. J Am Heart Assoc. 2017 May 18; 6 (5)
    View PubMed
  572. Relkin NR, Thomas RG, Rissman RA, Brewer JB, Rafii MS, van Dyck CH, Jack CR, Sano M, Knopman DS, Raman R, Szabo P, Gelmont DM, Fritsch S, Aisen PS, Alzheimer's Disease Cooperative Study. A phase 3 trial of IV immunoglobulin for Alzheimer disease. Neurology. 2017 May 2; 88 (18):1768-1775 Epub 2017 Apr 05
    View PubMed
  573. Josephs KA, Murray ME, Tosakulwong N, Whitwell JL, Knopman DS, Machulda MM, Weigand SD, Boeve BF, Kantarci K, Petrucelli L, Lowe VJ, Jack CR Jr, Petersen RC, Parisi JE, Dickson DW. Tau aggregation influences cognition and hippocampal atrophy in the absence of beta-amyloid: a clinico-imaging-pathological study of primary age-related tauopathy (PART). Acta Neuropathol. 2017 May; 133 (5):705-715 Epub 2017 Feb 03
    View PubMed
  574. Dearborn JL, Zhang Y, Qiao Y, Suri MFK, Liu L, Gottesman RF, Rawlings AM, Mosley TH, Alonso A, Knopman DS, Guallar E, Wasserman BA. Intracranial atherosclerosis and dementia: The Atherosclerosis Risk in Communities (ARIC) Study. Neurology. 2017 Apr 18; 88 (16):1556-1563 Epub 2017 Mar 22
    View PubMed
  575. Gottesman RF, Schneider AL, Zhou Y, Coresh J, Green E, Gupta N, Knopman DS, Mintz A, Rahmim A, Sharrett AR, Wagenknecht LE, Wong DF, Mosley TH. Association Between Midlife Vascular Risk Factors and Estimated Brain Amyloid Deposition. JAMA. 2017 Apr 11; 317 (14):1443-1450
    View PubMed
  576. Bressler J, Mosley TH, Penman A, Gottesman RF, Windham BG, Knopman DS, Wruck LM, Boerwinkle E. Genetic variants associated with risk of Alzheimer's disease contribute to cognitive change in midlife: The Atherosclerosis Risk in Communities Study. Am J Med Genet B Neuropsychiatr Genet. 2017 Apr; 174 (3):269-282 Epub 2016 Oct 26
    View PubMed
  577. Wennberg AMV, Savica R, Hagen CE, Roberts RO, Knopman DS, Hollman JH, Vemuri P, Jack CR Jr, Petersen RC, Mielke MM. Cerebral Amyloid Deposition Is Associated with Gait Parameters in the Mayo Clinic Study of Aging. J Am Geriatr Soc. 2017 Apr; 65 (4):792-799 Epub 2016 Nov 21
    View PubMed
  578. Carvalho DZ, St Louis EK, Boeve BF, Mielke MM, Przybelski SA, Knopman DS, Machulda MM, Roberts RO, Geda YE, Petersen RC, Jack CR Jr, Vemuri P. Excessive daytime sleepiness and fatigue may indicate accelerated brain aging in cognitively normal late middle-aged and older adults. Sleep Med. 2017 Apr; 32:236-243 Epub 2016 Nov 03
    View PubMed
  579. Tacik P, Sanchez-Contreras M, DeTure M, Murray ME, Rademakers R, Ross OA, Wszolek ZK, Parisi JE, Knopman DS, Petersen RC, Dickson DW. Clinicopathologic heterogeneity in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) due to microtubule-associated protein tau (MAPT) p.P301L mutation, including a patient with globular glial tauopathy. Neuropathol Appl Neurobiol. 2017 Apr; 43 (3):200-214 Epub 2017 Mar 08
    View PubMed
  580. Sprung J, Roberts RO, Knopman DS, Price LL, Schulz HP, Tatsuyama CL, Weingarten TN, Schroeder DR, Hanson AC, Petersen RC, Warner DO. Mild Cognitive Impairment and Exposure to General Anesthesia for Surgeries and Procedures: A Population-Based Case-Control Study. Anesth Analg. 2017 Apr; 124 (4):1277-1290
    View PubMed
  581. Jack CR Jr, Wiste HJ, Weigand SD, Therneau TM, Lowe VJ, Knopman DS, Gunter JL, Senjem ML, Jones DT, Kantarci K, Machulda MM, Mielke MM, Roberts RO, Vemuri P, Reyes DA, Petersen RC. Defining imaging biomarker cut points for brain aging and Alzheimer's disease. Alzheimers Dement. 2017 Mar; 13 (3):205-216 Epub 2016 Sept 30
    View PubMed
  582. Sarro L, Tosakulwong N, Schwarz CG, Graff-Radford J, Przybelski SA, Lesnick TG, Zuk SM, Reid RI, Raman MR, Boeve BF, Ferman TJ, Knopman DS, Comi G, Filippi M, Murray ME, Parisi JE, Dickson DW, Petersen RC, Jack CR Jr, Kantarci K. An investigation of cerebrovascular lesions in dementia with Lewy bodies compared to Alzheimer's disease. Alzheimers Dement. 2017 Mar; 13 (3):257-266 Epub 2016 Aug 10
    View PubMed
  583. Snyder HM, Ahles T, Calderwood S, Carrillo MC, Chen H, Chang CH, Craft S, De Jager P, Driver JA, Fillit H, Knopman D, Lotze M, Tierney MC, Petanceska S, Saykin A, Seshadri S, Shineman D, Ganguli M. Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies: A convening of the Alzheimer's Association & Alzheimer's Drug Discovery Foundation. Alzheimers Dement. 2017 Mar; 13 (3):267-273 Epub 2016 Dec 18
    View PubMed
  584. Krell-Roesch J, Vemuri P, Pink A, Roberts RO, Stokin GB, Mielke MM, Christianson TJ, Knopman DS, Petersen RC, Kremers WK, Geda YE. Association Between Mentally Stimulating Activities in Late Life and the Outcome of Incident Mild Cognitive Impairment, With an Analysis of the APOE epsilon4 Genotype. JAMA Neurol. 2017 Mar 1; 74 (3):332-338
    View PubMed
  585. Graff-Radford J, Aakre J, Savica R, Boeve B, Kremers WK, Ferman TJ, Jones DT, Kantarci K, Knopman DS, Dickson DW, Kukull WA, Petersen RC. Duration and Pathologic Correlates of Lewy Body Disease. JAMA Neurol. 2017 Mar 1; 74 (3):310-315
    View PubMed
  586. Graff-Radford J, Aakre J, Savica R, Boeve B, Kremers WK, Ferman TJ, Jones DT, Kantarci K, Knopman DS, Dickson DW, Kukull WA, Petersen RC. Duration and pathologic correlates of Lewy body disease Jama Neurology. 2017 Mar 1; 74: (3)308-13.
  587. Staubo SC, Aakre JA, Vemuri P, Syrjanen JA, Mielke MM, Geda YE, Kremers WK, Machulda MM, Knopman DS, Petersen RC, Jack CR Jr, Roberts RO. Mediterranean diet, micronutrients and macronutrients, and MRI measures of cortical thickness. Alzheimers Dement. 2017 Feb; 13(2):168-177. Epub 2016 Jul 25.
    View PubMed
  588. Hibar DP, Adams HHH, Jahanshad N, Chauhan G, Stein JL, Hofer E, Renteria ME, Bis JC, Arias-Vasquez A, Ikram MK, Desrivieres S, Vernooij MW, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Beecham AH, Beiser A, Bernard M, Blanton SH, Bohlken MM, Boks MP, Bralten J, Brickman AM, Carmichael O, Chakravarty MM, Chen Q, Ching CRK, Chouraki V, Cuellar-Partida G, Crivello F, Den Braber A, Doan NT, Ehrlich S, Giddaluru S, Goldman AL, Gottesman RF, Grimm O, Griswold ME, Guadalupe T, Gutman BA, Hass J, Haukvik UK, Hoehn D, Holmes AJ, Hoogman M, Janowitz D, Jia T, Jorgensen KN, Karbalai N, Kasperaviciute D, Kim S, Klein M, Kraemer B, Lee PH, Liewald DCM, Lopez LM, Luciano M, Macare C, Marquand AF, Matarin M, Mather KA, Mattheisen M, McKay DR, Milaneschi Y, Munoz Maniega S, Nho K, Nugent AC, Nyquist P, Loohuis LMO, Oosterlaan J, Papmeyer M, Pirpamer L, Putz B, Ramasamy A, Richards JS, Risacher SL, Roiz-Santianez R, Rommelse N, Ropele S, Rose EJ, Royle NA, Rundek T, Samann PG, Saremi A, Satizabal CL, Schmaal L, Schork AJ, Shen L, Shin J, Shumskaya E, Smith AV, Sprooten E, Strike LT, Teumer A, Tordesillas-Gutierrez D, Toro R, Trabzuni D, Trompet S, Vaidya D, Van der Grond J, Van der Lee SJ, Van der Meer D, Van Donkelaar MMJ, Van Eijk KR, Van Erp TGM, Van Rooij D, Walton E, Westlye LT, Whelan CD, Windham BG, Winkler AM, Wittfeld K, Woldehawariat G, Wolf C, Wolfers T, Yanek LR, Yang J, Zijdenbos A, Zwiers MP, Agartz I, Almasy L, Ames D, Amouyel P, Andreassen OA, Arepalli S, Assareh AA, Barral S, Bastin ME, Becker DM, Becker JT, Bennett DA, Blangero J, van Bokhoven H, Boomsma DI, Brodaty H, Brouwer RM, Brunner HG, Buckner RL, Buitelaar JK, Bulayeva KB, Cahn W, Calhoun VD, Cannon DM, Cavalleri GL, Cheng CY, Cichon S, Cookson MR, Corvin A, Crespo-Facorro B, Curran JE, Czisch M, Dale AM, Davies GE, De Craen AJM, De Geus EJC, De Jager PL, De Zubicaray GI, Deary IJ, Debette S, DeCarli C, Delanty N, Depondt C, DeStefano A, Dillman A, Djurovic S, Donohoe G, Drevets WC, Duggirala R, Dyer TD, Enzinger C, Erk S, Espeseth T, Fedko IO, Fernandez G, Ferrucci L, Fisher SE, Fleischman DA, Ford I, Fornage M, Foroud TM, Fox PT, Francks C, Fukunaga M, Gibbs JR, Glahn DC, Gollub RL, Goring HHH, Green RC, Gruber O, Gudnason V, Guelfi S, Haberg AK, Hansell NK, Hardy J, Hartman CA, Hashimoto R, Hegenscheid K, Heinz A, Le Hellard S, Hernandez DG, Heslenfeld DJ, Ho BC, Hoekstra PJ, Hoffmann W, Hofman A, Holsboer F, Homuth G, Hosten N, Hottenga JJ, Huentelman M, Hulshoff Pol HE, Ikeda M, Jack CR Jr, Jenkinson M, Johnson R, Jonsson EG, Jukema JW, Kahn RS, Kanai R, Kloszewska I, Knopman DS, Kochunov P, Kwok JB, Lawrie SM, Lemaitre H, Liu X, Longo DL, Lopez OL, Lovestone S, Martinez O, Martinot JL, Mattay VS, McDonald C, McIntosh AM, McMahon FJ, McMahon KL, Mecocci P, Melle I, Meyer-Lindenberg A, Mohnke S, Montgomery GW, Morris DW, Mosley TH, Muhleisen TW, Muller-Myhsok B, Nalls MA, et al, Schmidt R, Hernandez MCV, White T, Wright MJ. Novel genetic loci associated with hippocampal volume. Nat Commun. 2017 Jan 18; 8:13624
    View PubMed
  589. Ben-Avraham D, Karasik D, Verghese J, Lunetta KL, Smith JA, Eicher JD, Vered R, Deelen J, Arnold AM, Buchman AS, Tanaka T, Faul JD, Nethander M, Fornage M, Adams HH, Matteini AM, Callisaya ML, Smith AV, Yu L, De Jager PL, Evans DA, Gudnason V, Hofman A, Pattie A, Corley J, Launer LJ, Knopman DS, Parimi N, Turner ST, Bandinelli S, Beekman M, Gutman D, Sharvit L, Mooijaart SP, Liewald DC, Houwing-Duistermaat JJ, Ohlsson C, Moed M, Verlinden VJ, Mellstrom D, van der Geest JN, Karlsson M, Hernandez D, McWhirter R, Liu Y, Thomson R, Tranah GJ, Uitterlinden AG, Weir DR, Zhao W, Starr JM, Johnson AD, Ikram MA, Bennett DA, Cummings SR, Deary IJ, Harris TB, Kardia SL, Mosley TH, Srikanth VK, Windham BG, Newman AB, Walston JD, Davies G, Evans DS, Slagboom EP, Ferrucci L, Kiel DP, Murabito JM, Atzmon G. The complex genetics of gait speed: genome-wide meta-analysis approach. Aging (Albany NY). 2017 Jan 10; 9 (1):209-246
    View PubMed
  590. Kantarci K, Lowe VJ, Boeve BF, Senjem ML, Tosakulwong N, Lesnick TG, Spychalla AJ, Gunter JL, Fields JA, Graff-Radford J, Ferman TJ, Jones DT, Murray ME, Knopman DS, Jack CR Jr, Petersen RC. AV-1451 tau and beta-amyloid positron emission tomography imaging in dementia with Lewy bodies. Ann Neurol. 2017 Jan; 81 (1):58-67 Epub 2016 Dec 19
    View PubMed
  591. Machulda MM, Hagen CE, Wiste HJ, Mielke MM, Knopman DS, Roberts RO, Vemuri P, Lowe VJ, Jack CR Jr, Petersen RC. [Formula: see text]Practice effects and longitudinal cognitive change in clinically normal older adults differ by Alzheimer imaging biomarker status. Clin Neuropsychol. 2017 Jan; 31 (1):99-117 Epub 2016 Oct 11
    View PubMed
  592. Vemuri P, Knopman DS, Jack CR Jr, Lundt ES, Weigand SD, Zuk SM, Thostenson KB, Reid RI, Kantarci K, Slinin Y, Lakshminarayan K, Davey CS, Murray A. Association of Kidney Function Biomarkers with Brain MRI Findings: The BRINK Study. J Alzheimers Dis. 2017; 55(3):1069-1082.
    View PubMed
  593. Savica R, Wennberg AM, Hagen C, Edwards K, Roberts RO, Hollman JH, Knopman DS, Boeve BF, Machulda MM, Petersen RC, Mielke MM. Comparison of Gait Parameters for Predicting Cognitive Decline: The Mayo Clinic Study of Aging. J Alzheimers Dis. 2017; 55(2):559-567.
    View PubMed
  594. Bressler J, Knopman DS, Sharrett AR, Gottesman RF, Penman A, Chang PP, Rosamond WD, Boerwinkle E, Mosley TH. Incident Heart Failure and Cognitive Decline: The Atherosclerosis Risk in Communities Study. J Card Fail. 2017 Jan; 23 (1):47-55 Epub 2016 Nov 15
    View PubMed
  595. Vemuri P, Lowe VJ, Knopman DS, Senjem ML, Kemp BJ, Schwarz CG, Przybelski SA, Machulda MM, Petersen RC, Jack CR Jr. Tau-PET uptake: Regional variation in average SUVR and impact of amyloid deposition. Alzheimers Dement (Amst). 2017; 6:21-30 Epub 2016 Dec 21
    View PubMed
  596. Rabinovici GD, Carrillo MC, Forman M, DeSanti S, Miller DS, Kozauer N, Petersen RC, Randolph C, Knopman DS, Smith EE, Isaac M, Mattsson N, Bain LJ, Hendrix JA, Sims JR. Multiple comorbid neuropathologies in the setting of Alzheimer's disease neuropathology and implications for drug development. Alzheimers Dement (N Y). 2017 Jan; 3 (1):83-91 Epub 2016 Sept 20
    View PubMed
  597. Wiepert DA, Lowe VJ, Knopman DS, Boeve BF, Graff-Radford J, Petersen RC, Jack CR Jr, Jones DT. A robust biomarker of large-scale network failure in Alzheimer's disease. Alzheimers Dement (Amst). 2017; 6:152-161 Epub 2017 Jan 25
    View PubMed
  598. Lowe VJ, Lundt E, Knopman D, Senjem ML, Gunter JL, Schwarz CG, Kemp BJ, Jack CR Jr, Petersen RC. Comparison of [(18)F]Flutemetamol and [(11)C]Pittsburgh Compound-B in cognitively normal young, cognitively normal elderly, and Alzheimer's disease dementia individuals. Neuroimage Clin. 2017; 16:295-302 Epub 2017 Aug 14
    View PubMed
  599. Jung Y, Boot BP, Mielke MM, Ferman TJ, Geda YE, McDade E, Christianson TJH, Knopman DS, St Louis EK, Silber MH, Petersen RC, Boeve BF. Phenoconversion from probable rapid eye movement sleep behavior disorder to mild cognitive impairment to dementia in a population-based sample. Alzheimers Dement (Amst). 2017; 8:127-130 Epub 2017 May 30
    View PubMed
  600. Meyer ML, Palta P, Tanaka H, Deal JA, Wright J, Knopman DS, Griswold ME, Mosley TH, Heiss G. Association of Central Arterial Stiffness and Pressure Pulsatility with Mild Cognitive Impairment and Dementia: The Atherosclerosis Risk in Communities Study-Neurocognitive Study (ARIC-NCS). J Alzheimers Dis. 2017; 57 (1):195-204
    View PubMed
  601. Kantarci K, Lowe VJ, Boeve BF, Senjem ML, Tosakulwong N, Lesnick TG, Spychalla AJ, Gunter JL, Fields JA, Graff-Radford J, Ferman TJ, Jones DT, Murray ME, Knopman DS, Jack CR Jr, Petersen RC. AV-1451 tau and beta-amyloid positron emission tomography imaging in dementia with Lewy bodies Annals of Neurology. 2017 Jan; 81: (1)58-67.
  602. Li D, Misialek JR, Boerwinkle E, Gottesman RF, Sharrett AR, Mosley TH, Coresh J, Wruck LM, Knopman DS, Alonso A. Prospective associations of plasma phospholipids and mild cognitive impairment/dementia among African Americans in the ARIC Neurocognitive Study. Alzheimers Dement (Amst). 2017; 6:1-10 Epub 2016 Nov 01
    View PubMed
  603. Pink A, Przybelski SA, Krell-Roesch J, Stokin GB, Roberts RO, Mielke MM, Knopman DS, Jack CR, Petersen RC, Geda YE. Cortical Thickness and Depressive Symptoms in Cognitively Normal Individuals: The Mayo Clinic Study of Aging. J Alzheimers Dis. 2017; 58 (4):1273-1281
    View PubMed
  604. Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Renteria ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivieres S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Beiser A, Bernard M, Bis JC, Blanken LM, Blanton SH, Bohlken MM, Boks MP, Bralten J, Brickman AM, Carmichael O, Chakravarty MM, Chauhan G, Chen Q, Ching CR, Cuellar-Partida G, Braber AD, Doan NT, Ehrlich S, Filippi I, Ge T, Giddaluru S, Goldman AL, Gottesman RF, Greven CU, Grimm O, Griswold ME, Guadalupe T, Hass J, Haukvik UK, Hilal S, Hofer E, Hoehn D, Holmes AJ, Hoogman M, Janowitz D, Jia T, Kasperaviciute D, Kim S, Klein M, Kraemer B, Lee PH, Liao J, Liewald DC, Lopez LM, Luciano M, Macare C, Marquand A, Matarin M, Mather KA, Mattheisen M, Mazoyer B, McKay DR, McWhirter R, Milaneschi Y, Mirza-Schreiber N, Muetzel RL, Maniega SM, Nho K, Nugent AC, Loohuis LM, Oosterlaan J, Papmeyer M, Pappa I, Pirpamer L, Pudas S, Putz B, Rajan KB, Ramasamy A, Richards JS, Risacher SL, Roiz-Santianez R, Rommelse N, Rose EJ, Royle NA, Rundek T, Samann PG, Satizabal CL, Schmaal L, Schork AJ, Shen L, Shin J, Shumskaya E, Smith AV, Sprooten E, Strike LT, Teumer A, Thomson R, Tordesillas-Gutierrez D, Toro R, Trabzuni D, Vaidya D, Van der Grond J, Van der Meer D, Van Donkelaar MM, Van Eijk KR, Van Erp TG, Van Rooij D, Walton E, Westlye LT, Whelan CD, Windham BG, Winkler AM, Woldehawariat G, Wolf C, Wolfers T, Xu B, Yanek LR, Yang J, Zijdenbos A, Zwiers MP, Agartz I, Aggarwal NT, Almasy L, Ames D, Amouyel P, Andreassen OA, Arepalli S, Assareh AA, Barral S, Bastin ME, Becker DM, Becker JT, Bennett DA, Blangero J, van Bokhoven H, Boomsma DI, Brodaty H, Brouwer RM, Brunner HG, Buckner RL, Buitelaar JK, Bulayeva KB, Cahn W, Calhoun VD, Cannon DM, Cavalleri GL, Chen C, Cheng CY, Cichon S, Cookson MR, Corvin A, Crespo-Facorro B, Curran JE, Czisch M, Dale AM, Davies GE, De Geus EJ, De Jager PL, de Zubicaray GI, Delanty N, Depondt C, DeStefano AL, Dillman A, Djurovic S, Donohoe G, Drevets WC, Duggirala R, Dyer TD, Erk S, Espeseth T, Evans DA, Fedko IO, Fernandez G, Ferrucci L, Fisher SE, Fleischman DA, Ford I, Foroud TM, Fox PT, Francks C, Fukunaga M, Gibbs JR, Glahn DC, Gollub RL, Goring HH, Grabe HJ, Green RC, Gruber O, Gudnason V, Guelfi S, Hansell NK, Hardy J, Hartman CA, Hashimoto R, Hegenscheid K, Heinz A, Le Hellard S, Hernandez DG, Heslenfeld DJ, Ho BC, Hoekstra PJ, Hoffmann W, Hofman A, Holsboer F, Homuth G, Hosten N, Hottenga JJ, Hulshoff Pol HE, Ikeda M, Ikram MK, Jack CR Jr, Jenkinson M, Johnson R, Jonsson EG, Jukema JW, Kahn RS, Kanai R, Kloszewska I, Knopman DS, Kochunov P, Kwok JB, Lawrie SM, Lemaitre H, Liu X, Longo DL, Longstreth WT Jr, Lopez OL, Lovestone S, Martinez O, Martinot JL, Mattay VS, McDonald C, McIntosh AM, McMahon KL, McMahon FJ, Mecocci P, Melle I, Meyer-Lindenberg A, Mohnke S, et al, Schmidt R, Hernandez MC. Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nat Neurosci. 2016 Dec; 19 (12):1569-1582 Epub 2016 Oct 03
    View PubMed
  605. Pottier C, Ravenscroft TA, Brown PH, Finch NA, Baker M, Parsons M, Asmann YW, Ren Y, Christopher E, Levitch D, van Blitterswijk M, Cruchaga C, Campion D, Nicolas G, Richard AC, Guerreiro R, Bras JT, Zuchner S, Gonzalez MA, Bu G, Younkin S, Knopman DS, Josephs KA, Parisi JE, Petersen RC, Ertekin-Taner N, Graff-Radford NR, Boeve BF, Dickson DW, Rademakers R. TYROBP genetic variants in early-onset Alzheimer's disease. Neurobiol Aging. 2016 Dec; 48:222.e9-222.e15 Epub 2016 Aug 08
    View PubMed
  606. Krell-Roesch J, Pink A, Roberts RO, Stokin GB, Mielke MM, Spangehl KA, Bartley MM, Knopman DS, Christianson TJ, Petersen RC, Geda YE. Timing of Physical Activity, Apolipoprotein E epsilon4 Genotype, and Risk of Incident Mild Cognitive Impairment. J Am Geriatr Soc. 2016 Dec; 64 (12):2479-2486 Epub 2016 Nov 01
    View PubMed
  607. Labbé C, Heckman MG, Lorenzo-Betancor O, Soto-Ortolaza AI, Walton RL, Murray ME, Allen M, Uitti RJ, Wszolek ZK, Smith GE, Kantarci K, Knopman DS, Lowe VJ, Jack CR Jr, Ertekin-Taner N, Hassan A, Savica R, Petersen RC, Parisi JE, Maraganore DM, Graff-Radford NR, Ferman TJ, Boeve BF, Dickson DW, Ross OA. MAPT haplotype H1G is associated with increased risk of dementia with Lewy bodies. Alzheimers Dement. 2016 Dec; 12(12):1297-1304. Epub 2016 Jun 07.
    View PubMed
  608. Dage JL, Wennberg AMV, Airey DC, Hagen CE, Knopman DS, Machulda MM, Roberts RO, Jack CR Jr, Petersen RC, Mielke MM. Levels of tau protein in plasma are associated with neurodegeneration and cognitive function in a population-based elderly cohort. Alzheimers Dement. 2016 Dec; 12 (12):1226-1234 Epub 2016 July 18
    View PubMed
  609. Adams HHH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Renteria ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivieres S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Beiser A, Bernard M, Bis JC, Blanken LME, Blanton SH, Bohlken MM, Boks MP, Bralten J, Brickman AM, Carmichael O, Chakravarty MM, Chauhan G, Chen Q, Ching CRK, Cuellar-Partida G, Den Braber A, Doan NT, Ehrlich S, Filippi I, Ge T, Giddaluru S, Goldman AL, Gottesman RF, Greven CU, Grimm O, Griswold ME, Guadalupe T, Hass J, Haukvik UK, Hilal S, Hofer E, Hoehn D, Holmes AJ, Hoogman M, Janowitz D, Jia T, Kasperaviciute D, Kim S, Klein M, Kraemer B, Lee PH, Liao J, Liewald DCM, Lopez LM, Luciano M, Macare C, Marquand A, Matarin M, Mather KA, Mattheisen M, Mazoyer B, Mckay DR, McWhirter R, Milaneschi Y, Mirza-Schreiber N, Muetzel RL, Maniega SM, Nho K, Nugent AC, Loohuis LMO, Oosterlaan J, Papmeyer M, Pappa I, Pirpamer L, Pudas S, Puetz B, Rajan KB, Ramasamy A, Richards JS, Risacher SL, Roiz-Santianez R, Rommelse N, Rose EJ, Royle NA, Rundek T, Samann PG, Satizabal CL, Schmaal L, Schork AJ, Shen L, Shin J, Shumskaya E, Smith AV, Sprooten E, Strike LT, Teumer A, Thomson R, Tordesillas-Gutierrez D, Toro R, Trabzuni D, Vaidya D, Van der Grond J, Van der Meer D, Van Donkelaar MMJ, Van Eijk KR, Van Erp TGM, Van Rooij D, Walton E, Westlye LT, Whelan CD, Windham BG, Winkler AM, Woldehawariat G, Wolf C, Wolfers T, Xu B, Yanek LR, Yang JY, Zijdenbos A, Zwiers MP, Agartz I, Aggarwal NT, Almasy L, Ames D, Amouyel P, Andreassen OA, Arepalli S, Assareh AA, Barral S, Bastin ME, Becker DM, Becker JT, Bennett DA, Blangero J, van Bokhoven H, Boomsma DI, Brodaty H, Brouwer RM, Brunner HG, Buckner RL, Buitelaar JK, Bulayeva KB, Cahn W, Calhoun VD, Cannon DM, Cavalleri GL, Chen C, Cheng CY, Cichon S, Cookson MR, Corvin A, Crespo-Facorro B, Curran JE, Czisch M, Dale AM, Davies GE, De Geus EJC, De Jager PL, de Zubicaray GI, Delanty N, Depondt C, DeStefano AL, Dillman A, Djurovic S, Donohoe G, Drevets WC, Duggirala R, Dyer TD, Erk S, Espeseth T, Evans DA, Fedko I, Fernandez G, Ferrucci L, Fisher SE, Fleischman DA, Ford I, Foroud TM, Fox PT, Francks C, Fukunaga M, Gibbs JR, Glahn DC, Gollub RL, Goring HHH, Grabe HJ, Green RC, Gruber O, Gudnason V, Guelfi S, Hansell NK, Hardy J, Hartman CA, Hashimoto R, Hegenscheid K, Heinz A, Le Hellard S, Hernandez DG, Heslenfeld DJ, Ho BC, Hoekstra PJ, Hoffmann W, Hofman A, Holsboer F, Homuth G, Hosten N, Hottenga JJ, Pol HEH, Ikeda M, Ikram MK, Jack CR, Jenldnson M, Johnson R, Jonsson EG, Jukema JW, Kahn RS, Kanai R, Kloszewska I, Knopman DS, Kochunov P, Kwok JB, Lawrie SM, Lemaitre H, Liu XM, Longo DL, Longstreth WT, Lopez OL, Lovestone S, Martinez O, Martinot JL, Mattay VS, McDonald C, McIntosh AM, McMahon KL, McMahon FJ, Mecocci P, Melle I, Meyer-Lindenberg A, Mohnke S, Montgomery GW, Morris DW, Mosley TH, Muhleisen TW, Muller-Myhsok B, Nalls MA, Nauck M, Nichols TE, Niessen WJ, Nothen MM, Nyberg L, Ohi K, Olvera RL, Ophoff RA, Pandolfo M, Paus T, Pausova Z, Penninx BWJH, Pike GB, Potkin SG, Psaty BM, Reppermund S, Rietschel M, Roffman JL, Romanczuk-Seiferth N, Rotter JI, Ryten M, Sacco RL, Sachdev PS, Saykin AJ, Schmidt R, Schofield PR, Sigurdsson S, Simmons A, Singleton A, Sisodiya SM, Smith C, Smoller JW, Soininen H, Srikanth V, Steen VM, Stott DJ, Sussmann JE, Thalamuthu A, Tiemeier H, Toga AW, Traynor BJ, Troncoso J, Turner JA, Tzourio C, Uitterlinden AG, Hernandez MCV, Van der Brug M, Van der Lugt A, Van der Wee NJA, Van Duijn CM, Van Haren NEM, Van't Ent D, Van Tol MJ, Vardarajan BN, Veltman DJ, Vernooij MW, Volzke H, Walter H, Wardlaw JM, Wassink TH, Weale ME, Weinberger DR, Weiner MW, Wen W, Westman E, White T, Wong TY, Wright CB, Zielke HR, Zonderman AB, Deary IJ, DeCarli C, Schmidt H, Martin NG, De Craen AJM, Wright MJ, Launer LJ, Schumann G, Fornage M, Franke B, Debette S, Medland SE, Ikram MA, Thompson PM. Novel genetic loci underlying human intracranial volume identified through genome-wide association Nature Neuroscience. 2016 Dec; 19: (12)1569-82.
  610. Kantarci K, Lesnick T, Ferman TJ, Przybelski SA, Boeve BF, Smith GE, Kremers WK, Knopman DS, Jack CR Jr, Petersen RC. Hippocampal volumes predict risk of dementia with Lewy bodies in mild cognitive impairment. Neurology. 2016 Nov 29; 87 (22):2317-2323 Epub 2016 Nov 02
    View PubMed
  611. Knopman DS. Alzheimer disease: Preclinical Alzheimer disease - the new frontier. Nat Rev Neurol 2016 Nov; 12 (11):620-621 Epub 2016 Oct 07
    View PubMed
  612. Sarro L, Senjem ML, Lundt ES, Przybelski SA, Lesnick TG, Graff-Radford J, Boeve BF, Lowe VJ, Ferman TJ, Knopman DS, Comi G, Filippi M, Petersen RC, Jack CR Jr, Kantarci K. Amyloid-beta deposition and regional grey matter atrophy rates in dementia with Lewy bodies. Brain. 2016 Oct; 139 (Pt 10):2740-2750 Epub 2016 July 24
    View PubMed
  613. Knopman DS, Jack CR Jr, Lundt ES, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, Petersen RC. Evolution of neurodegeneration-imaging biomarkers from clinically normal to dementia in the Alzheimer disease spectrum. Neurobiol Aging. 2016 Oct; 46:32-42 Epub 2016 June 16
    View PubMed
  614. Heckman MG, Soto-Ortolaza AI, Contreras MYS, Murray ME, Pedraza O, Diehl NN, Walton R, Labbé C, Lorenzo-Betancor O, Uitti RJ, van Gerpen J, Ertekin-Taner N, Smith GE, Kantarci K, Savica R, Jones DT, Graff-Radford J, Knopman DS, Lowe VJ, Jack CR Jr, Petersen RC, Parisi JE, Rademakers R, Wszolek ZK, Graff-Radford NR, Ferman TJ, Dickson DW, Boeve BF, Ross OA. LRRK2 variation and dementia with Lewy bodies. Parkinsonism Relat Disord. 2016 Oct; 31:98-103. Epub 2016 Jul 29.
    View PubMed
  615. Knopman DS. Behavioral Variant Frontotemporal Dementia: One Syndrome, Several Circuits, Many Mechanisms. JAMA Neurol 2016 Sep 1; 73 (9):1051-2
    View PubMed
  616. Hodges K, Brewer SS, Labbé C, Soto-Ortolaza AI, Walton RL, Strongosky AJ, Uitti RJ, van Gerpen JA, Ertekin-Taner N, Kantarci K, Lowe VJ, Parisi JE, Savica R, Graff-Radford J, Jones DT, Knopman DS, Petersen RC, Murray ME, Graff-Radford NR, Ferman TJ, Dickson DW, Wszolek ZK, Boeve BF, Ross OA, Lorenzo-Betancor O. RAB39B gene mutations are not a common cause of Parkinson's disease or dementia with Lewy bodies. Neurobiol Aging. 2016 Sep; 45:107-108. Epub 2016 Mar 24.
    View PubMed
  617. Knopman DS, Jack CR Jr, Wiste HJ, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, Petersen RC. Age and neurodegeneration imaging biomarkers in persons with Alzheimer disease dementia. Neurology. 2016 Aug 16; 87 (7):691-8 Epub 2016 July 15
    View PubMed
  618. Kramer NJ, Carlomagno Y, Zhang YJ, Almeida S, Cook CN, Gendron TF, Prudencio M, Van Blitterswijk M, Belzil V, Couthouis J, Paul JW 3rd, Goodman LD, Daughrity L, Chew J, Garrett A, Pregent L, Jansen-West K, Tabassian LJ, Rademakers R, Boylan K, Graff-Radford NR, Josephs KA, Parisi JE, Knopman DS, Petersen RC, Boeve BF, Deng N, Feng Y, Cheng TH, Dickson DW, Cohen SN, Bonini NM, Link CD, Gao FB, Petrucelli L, Gitler AD. Spt4 selectively regulates the expression of C9orf72 sense and antisense mutant transcripts. Science. 2016 Aug 12; 353 (6300):708-12
    View PubMed
  619. Gottesman RF, Schneider AL, Zhou Y, Chen X, Green E, Gupta N, Knopman DS, Mintz A, Rahmim A, Sharrett AR, Wagenknecht LE, Wong DF, Mosley TH Jr. The ARIC-PET amyloid imaging study: Brain amyloid differences by age, race, sex, and APOE. Neurology. 2016 Aug 2; 87 (5):473-80 Epub 2016 July 01
    View PubMed
  620. Jack CR Jr, Bennett DA, Blennow K, Carrillo MC, Feldman HH, Frisoni GB, Hampel H, Jagust WJ, Johnson KA, Knopman DS, Petersen RC, Scheltens P, Sperling RA, Dubois B. A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers. Neurology. 2016 Aug 2; 87 (5):539-47 Epub 2016 July 01
    View PubMed
  621. Schott JM, Crutch SJ, Carrasquillo MM, Uphill J, Shakespeare TJ, Ryan NS, Yong KX, Lehmann M, Ertekin-Taner N, Graff-Radford NR, Boeve BF, Murray ME, Khan QU, Petersen RC, Dickson DW, Knopman DS, Rabinovici GD, Miller BL, Gonzalez AS, Gil-Neciga E, Snowden JS, Harris J, Pickering-Brown SM, Louwersheimer E, van der Flier WM, Scheltens P, Pijnenburg YA, Galasko D, Sarazin M, Dubois B, Magnin E, Galimberti D, Scarpini E, Cappa SF, Hodges JR, Halliday GM, Bartley L, Carrillo MC, Bras JT, Hardy J, Rossor MN, Collinge J, Fox NC, Mead S. Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease. Alzheimers Dement. 2016 Aug; 12 (8):862-71 Epub 2016 Mar 15
    View PubMed
  622. Walton RL, Soto-Ortolaza AI, Murray ME, Lorenzo-Betancor O, Ogaki K, Heckman MG, Rayaprolu S, Rademakers R, Ertekin-Taner N, Uitti RJ, van Gerpen JA, Wszolek ZK, Smith GE, Kantarci K, Lowe VJ, Parisi JE, Jones DT, Savica R, Graff-Radford J, Knopman DS, Petersen RC, Graff-Radford NR, Ferman TJ, Dickson DW, Boeve BF, Ross OA, Labbé C. TREM2 p.R47H substitution is not associated with dementia with Lewy bodies. Neurol Genet. 2016 Aug; 2(4):e85. Epub 2016 Jul 14.
    View PubMed
  623. Pakhomov SVS, Eberly L, Knopman D. Characterizing cognitive performance in a large longitudinal study of aging with computerized semantic indices of verbal fluency. Neuropsychologia. 2016 Aug; 89:42-56 Epub 2016 May 28
    View PubMed
  624. Power MC, Schneider AL, Wruck L, Griswold M, Coker LH, Alonso A, Jack CR Jr, Knopman D, Mosley TH, Gottesman RF. Life-course blood pressure in relation to brain volumes. Alzheimers Dement. 2016 Aug; 12 (8):890-9 Epub 2016 Apr 29
    View PubMed
  625. Krell-Roesch J, Ruider H, Lowe VJ, Stokin GB, Pink A, Roberts RO, Mielke MM, Knopman DS, Christianson TJ, Machulda MM, Jack CR, Petersen RC, Geda YE. FDG-PET and Neuropsychiatric Symptoms among Cognitively Normal Elderly Persons: The Mayo Clinic Study of Aging. J Alzheimers Dis. 2016 Jul 14; 53 (4):1609-16
    View PubMed
  626. Kats D, Patel MD, Palta P, Meyer ML, Gross AL, Whitsel EA, Knopman D, Alonso A, Mosley TH, Heiss G. Social support and cognition in a community-based cohort: the Atherosclerosis Risk in Communities (ARIC) study. Age Ageing. 2016 Jul; 45 (4):475-80 Epub 2016 Apr 21
    View PubMed
  627. Bang J, Lobach IV, Lang AE, Grossman M, Knopman DS, Miller BL, Schneider LS, Doody RS, Lees A, Gold M, Morimoto BH, Boxer AL, AL-108-231 Investigators. Predicting disease progression in progressive supranuclear palsy in multicenter clinical trials. Parkinsonism Relat Disord. 2016 Jul; 28:41-48 Epub 2016 Apr 18
    View PubMed
  628. Graff-Radford J, Lesnick TG, Boeve BF, Przybelski SA, Jones DT, Senjem ML, Gunter JL, Ferman TJ, Knopman DS, Murray ME, Dickson DW, Sarro L, Jack CR Jr, Petersen RC, Kantarci K. Predicting Survival in Dementia With Lewy Bodies With Hippocampal Volumetry. Mov Disord. 2016 Jul; 31 (7):989-94 Epub 2016 May 23
    View PubMed
  629. Lowe VJ, Curran G, Fang P, Liesinger AM, Josephs KA, Parisi JE, Kantarci K, Boeve BF, Pandey MK, Bruinsma T, Knopman DS, Jones DT, Petrucelli L, Cook CN, Graff-Radford NR, Dickson DW, Petersen RC, Jack CR Jr, Murray ME. An autoradiographic evaluation of AV-1451 Tau PET in dementia. Acta Neuropathol Commun. 2016 Jun 13; 4 (1):58 Epub 2016 June 13
    View PubMed
  630. Vassilaki M, Aakre JA, Mielke MM, Geda YE, Kremers WK, Alhurani RE, Machulda MM, Knopman DS, Petersen RC, Lowe VJ, Jack CR Jr, Roberts RO. Multimorbidity and neuroimaging biomarkers among cognitively normal persons. Neurology. 2016 May 31; 86 (22):2077-84 Epub 2016 Apr 13
    View PubMed
  631. Jaeger PA, Lucin KM, Britschgi M, Vardarajan B, Huang RP, Kirby ED, Abbey R, Boeve BF, Boxer AL, Farrer LA, Finch N, Graff-Radford NR, Head E, Hofree M, Huang R, Johns H, Karydas A, Knopman DS, Loboda A, Masliah E, Narasimhan R, Petersen RC, Podtelezhnikov A, Pradhan S, Rademakers R, Sun CH, Younkin SG, Miller BL, Ideker T, Wyss-Coray T. Erratum to: Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain. Mol Neurodegener. 2016 May 23; 11 (1):42
    View PubMed
  632. Wennberg AM, Gustafson D, Hagen CE, Roberts RO, Knopman D, Jack C, Petersen RC, Mielke MM. Serum Adiponectin Levels, Neuroimaging, and Cognition in the Mayo Clinic Study of Aging. J Alzheimers Dis. 2016 May 4; 53 (2):573-81
    View PubMed
  633. Vemuri P, Knopman DS. The role of cerebrovascular disease when there is concomitant Alzheimer disease. Biochim Biophys Acta. 2016 May; 1862 (5):952-6 Epub 2015 Sept 25
    View PubMed
  634. Jaeger PA, Lucin KM, Britschgi M, Vardarajan B, Huang RP, Kirby ED, Abbey R, Boeve BF, Boxer AL, Farrer LA, Finch N, Graff-Radford NR, Head E, Hofree M, Huang R, Johns H, Karydas A, Knopman DS, Loboda A, Masliah E, Narasimhan R, Petersen RC, Podtelezhnikov A, Pradhan S, Rademakers R, Sun CH, Younkin SG, Miller BL, Ideker T, Wyss-Coray T. Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain. Mol Neurodegener. 2016 Apr 26; 11:31
    View PubMed
  635. Alhurani RE, Vassilaki M, Aakre JA, Mielke MM, Kremers WK, Machulda MM, Geda YE, Knopman DS, Petersen RC, Roberts RO. Decline in Weight and Incident Mild Cognitive Impairment: Mayo Clinic Study of Aging. JAMA Neurol. 2016 Apr; 73 (4):439-46
    View PubMed
  636. Graff-Radford J, Madhavan M, Vemuri P, Rabinstein AA, Cha RH, Mielke MM, Kantarci K, Lowe V, Senjem ML, Gunter JL, Knopman DS, Petersen RC, Jack CR Jr, Roberts RO. Atrial fibrillation, cognitive impairment, and neuroimaging. Alzheimers Dement. 2016 Apr; 12 (4):391-8 Epub 2015 Oct 23
    View PubMed
  637. Murray AM, Bell EJ, Tupper DE, Davey CS, Pederson SL, Amiot EM, Miley KM, McPherson L, Heubner BM, Gilbertson DT, Foley RN, Drawz PE, Slinin Y, Rossom RC, Lakshminarayan K, Vemuri P, Jack CR, Knopman DS. The Brain in Kidney Disease (BRINK) Cohort Study: Design and Baseline Cognitive Function. Am J Kidney Dis. 2016 Apr; 67 (4):593-600 Epub 2015 Dec 29
    View PubMed
  638. Rabinovici GD, Karlawish J, Knopman D, Snyder HM, Sperling R, Carrillo MC. Testing and disclosures related to amyloid imaging and Alzheimer's disease: Common questions and fact sheet summary. Alzheimers Dement. 2016 Apr; 12: (4)510-5.
    View PubMed
  639. Vemuri P, Lesnick TG, Przybelski SA, Knopman DS, Machulda M, Lowe VJ, Mielke MM, Roberts RO, Gunter JL, Senjem ML, Geda YE, Rocca WA, Petersen RC, Jack CR Jr. Effect of intellectual enrichment on AD biomarker trajectories: Longitudinal imaging study. Neurology. 2016 Mar 22; 86 (12):1128-35 Epub 2016 Feb 24
    View PubMed
  640. Mielke MM, Machulda MM, Hagen CE, Christianson TJ, Roberts RO, Knopman DS, Vemuri P, Lowe VJ, Kremers WK, Jack CR Jr, Petersen RC. Influence of amyloid and APOE on cognitive performance in a late middle-aged cohort. Alzheimers Dement. 2016 Mar; 12 (3):281-91 Epub 2015 Nov 19
    View PubMed
  641. Jones DT, Knopman DS, Gunter JL, Graff-Radford J, Vemuri P, Boeve BF, Petersen RC, Weiner MW, Jack CR Jr, Alzheimer's Disease Neuroimaging Initiative. Cascading network failure across the Alzheimer's disease spectrum. Brain. 2016 Feb; 139 (Pt 2):547-62 Epub 2015 Nov 19
    View PubMed
  642. Jack CR Jr, Knopman DS, Chetelat G, Dickson D, Fagan AM, Frisoni GB, Jagust W, Mormino EC, Petersen RC, Sperling RA, van der Flier WM, Villemagne VL, Visser PJ, Vos SJ. Suspected non-Alzheimer disease pathophysiology--concept and controversy. Nat Rev Neurol. 2016 Feb; 12 (2):117-24 Epub 2016 Jan 18
    View PubMed
  643. Sprung J, Roberts RO, Knopman DS, Olive DM, Gappa JL, Sifuentes VL, Behrend TL, Farmer JD, Weingarten TN, Hanson AC, Schroeder DR, Petersen RC, Warner DO. Association of Mild Cognitive Impairment With Exposure to General Anesthesia for Surgical and Nonsurgical Procedures: A Population-Based Study. Mayo Clin Proc. 2016 Feb; 91 (2):208-17 Epub 2016 Jan 20
    View PubMed
  644. Ibrahim-Verbaas CA, Bressler J, Debette S, Schuur M, Smith AV, Bis JC, Davies G, Trompet S, Smith JA, Wolf C, Chibnik LB, Liu Y, Vitart V, Kirin M, Petrovic K, Polasek O, Zgaga L, Fawns-Ritchie C, Hoffmann P, Karjalainen J, Lahti J, Llewellyn DJ, Schmidt CO, Mather KA, Chouraki V, Sun Q, Resnick SM, Rose LM, Oldmeadow C, Stewart M, Smith BH, Gudnason V, Yang Q, Mirza SS, Jukema JW, deJager PL, Harris TB, Liewald DC, Amin N, Coker LH, Stegle O, Lopez OL, Schmidt R, Teumer A, Ford I, Karbalai N, Becker JT, Jonsdottir MK, Au R, Fehrmann R, Herms S, Nalls M, Zhao W, Turner ST, Yaffe K, Lohman K, van Swieten JC, Kardia S, Knopman DS, Meeks WM, Heiss G, Holliday EG, Schofield PW, Tanaka T, Stott DJ, Wang J, Ridker P, Gow AJ, Pattie A, Starr JM, Hocking LJ, Armstrong NJ, McLachlan S, Shulman JM, Pilling LC, Eiriksdottir G, Scott RJ, Kochan NA, Palotie A, Hsieh YC, Eriksson JG, Penman A, Gottesman RF, Oostra BA, Yu L, DeStefano AL, Beiser A, Garcia M, Rotter JI, Nothen MM, Hofman A, Slagboom PE, Westendorp R, Buckley BM, Wolf PA, Uitterlinden AG, Psaty BM, Grabe HJ, Bandinelli S, Chasman DI, Grodstein F, Raikkonen K, Lambert JC, Porteous DJ, Price JF, Sachdev PS, Ferrucci L, Attia JR, Rudan I, Hayward C, Wright AF, Wilson JF, Cichon S, Franke L, Schmidt H, Ding J, de Craen A, Fornage M, Bennett DA, Deary IJ, Ikram MA, Launer LJ, Fitzpatrick AL, Seshadri S, van Duijn CM, Mosley TH, Generation Scotland. GWAS for executive function and processing speed suggests involvement of the CADM2 gene. Mol Psychiatry. 2016 Feb; 21 (2):189-197 Epub 2015 Apr 14
    View PubMed
  645. Iturria-Medina Y, Sotero RC, Toussaint PJ, Mateos-Perez JM, Evans AC, Weiner MW, Aisen P, Petersen R, Jack CR, Jagust W, Trojanowki JQ, Toga AW, Beckett L, Green RC, Saykin AJ, Morris J, Shaw LM, Khachaturian Z, Sorensen G, Kuller L, Raichle M, Paul S, Davies P, Fillit H, Hefti F, Holtzman D, Mesulam MM, Potter W, Snyder P, Schwartz A, Montine T, Thomas RG, Donohue M, Walter S, Gessert D, Sather T, Jiminez G, Harvey D, Bernstein M, Fox N, Thompson P, Schuff N, Borowski B, Gunter J, Senjem M, Vemuri P, Jones D, Kantarci K, Ward C, Koeppe RA, Foster N, Reiman EM, Chen K, Mathis C, Landau S, Cairns NJ, Householder E, Taylor-Reinwald L, Lee V, Korecka M, Figurski M, Crawford K, Neu S, Foroud TM, Potkin S, Shen L, Faber K, Kim S, Nho K, Thal L, Buckholtz N, Albert M, Frank R, Hsiao J, Kaye J, Quinn J, Lind B, Carter R, Dolen S, Schneider LS, Pawluczyk S, Beccera M, Teodoro L, Spann BM, Brewer J, Vanderswag H, Fleisher A, Heidebrink JL, Lord JL, Mason SS, Albers CS, Knopman D, Johnson K, Doody RS, Villanueva-Meyer J, Chowdhury M, Rountree S, Dang M, Stern Y, Honig LS, Bell KL, Ances B, Carroll M, Leon S, Mintun MA, Schneider S, Oliver A, Marson D, Griffith R, Clark D, Geldmacher D, Brockington J, Roberson E, Grossman H, Mitsis E, De Toledo-Morrell L, Shah RC, Duara R, Varon D, Greig MT, Roberts P, Albert M, Onyike C, D'Agostino D, Kielb S, Galvin JE, Cerbone B, Michel CA, Rusinek H, De Leon MJ, Glodzik L, De Santi S, Doraiswamy PM, Petrella JR, Wong TZ, Arnold SE, Karlawish JH, Wolk D, Smith CD, Jicha G, Hardy P, Sinha P, Oates E, Conrad G, Lopez OL, Oakley M, Simpson DM, Porsteinsson AP, Goldstein BS, Martin K, Makino KM, Ismail MS, Brand C, Mulnard RA, Thai G, Mc-Adams-Ortiz C, Womack K, Mathews D, Quiceno M, Diaz-Arrastia R, King R, Weiner M, Martin-Cook K, DeVous M, Levey AI, Lah JJ, Cellar JS, Burns JM, Anderson HS, Swerdlow RH, Apostolova L, Tingus K, Woo E, Silverman DHS, Lu PH, Bartzokis G, Graff-Radford NR, Parfitt F, Kendall T, Johnson H, Farlow MR, Hake A, Matthews BR, Herring S, Hunt C, Van Dyck CH, Carson RE, MacAvoy MG, Chertkow H, Bergman H, Hosein C, Black S, Stefanovic B, Caldwell C, Hsiung GYR, Feldman H, Mudge B, Assaly M, Kertesz A, Rogers J, Bernick C, Munic D, Kerwin D, Mesulam MM, Lipowski K, Wu CK, Johnson N, Sadowsky C, Martinez W, Villena T, Turner RS, Johnson K, Reynolds B, Sperling RA, Johnson KA, Marshall G, Frey M, Lane B, Rosen A, Tinklenberg J, Sabbagh MN, Belden CM, Jacobson SA, Sirrel SA, Kowall N, Killiany R, Budson AE, Norbash A, Johnson PL, Allard J, Lerner A, Ogrocki P, Hudson L, Fletcher E, Carmichael O, Olichney J, DeCarli C, Kittur S, Borrie M, Lee TY, Bartha R, Johnson S, Asthana S, Carlsson CM, Potkin SG, Preda A, Nguyen D, Tariot P, Reeder S, Bates V, Capote H, Rainka M, Scharre DW, Kataki M, Adeli A, Zimmerman EA, Celmins D, Brown AD, Pearlson GD, Blank K, Anderson K, Santulli RB, Kitzmiller TJ, Schwartz ES, Sink KM, Williamson JD, Garg P, Watkins F, Ott BR, Querfurth H, Tremont G, Salloway S, Malloy P, Correia S, Rosen HJ, Miller BL, Mintzer J, Spicer K, Bachman D, Finger E, Pasternak S, Rachinsky I, Drost D, Pomara N, Hernando R, Sarrael A, Schultz SK, Ponto LLB, Shim H, Smith KE, Relkin N, Chaing G, Raudin L, Smith A, Fargher K, Raj BA, Neylan T, Grafman J, Davis M, Morrison R, Hayes J, Finley S, Friedl K, Fleischman D, Arfanakis K, James O, Massoglia D, Fruehling JJ, Harding S, Peskind ER, Petrie EC, Li G, Yesavage JA, Taylor JL, Furst AJ. Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis Nature Communications. 2016; 7:11934.
  646. Knopman DS, Gottesman RF, Sharrett AR, Wruck LM, Windham BG, Coker L, Schneider AL, Hengrui S, Alonso A, Coresh J, Albert MS, Mosley TH Jr. Mild Cognitive Impairment and Dementia Prevalence: The Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS). Alzheimers Dement (Amst). 2016; 2:1-11
    View PubMed
  647. Petersen RC, Wiste HJ, Weigand SD, Rocca WA, Roberts RO, Mielke MM, Lowe VJ, Knopman DS, Pankratz VS, Machulda MM, Geda YE, Jack CR Jr. Association of Elevated Amyloid Levels With Cognition and Biomarkers in Cognitively Normal People From the Community. JAMA Neurol. 2016 Jan; 73 (1):85-92
    View PubMed
  648. Jack CR Jr, Therneau TM, Wiste HJ, Weigand SD, Knopman DS, Lowe VJ, Mielke MM, Vemuri P, Roberts RO, Machulda MM, Senjem ML, Gunter JL, Rocca WA, Petersen RC. Transition rates between amyloid and neurodegeneration biomarker states and to dementia: a population-based, longitudinal cohort study. Lancet Neurol. 2016 Jan; 15 (1):56-64 Epub 2015 Nov 18
    View PubMed
  649. Roberts RO, Christianson TJ, Kremers WK, Mielke MM, Machulda MM, Vassilaki M, Alhurani RE, Geda YE, Knopman DS, Petersen RC. Association Between Olfactory Dysfunction and Amnestic Mild Cognitive Impairment and Alzheimer Disease Dementia. JAMA Neurol. 2016 Jan; 73 (1):93-101
    View PubMed
  650. Li D, Misialek JR, Boerwinkle E, Gottesman RF, Sharrett AR, Mosley TH, Coresh J, Wruck LM, Knopman DS, Alonso A. Plasma phospholipids and prevalence of mild cognitive impairment and/or dementia in the ARIC Neurocognitive Study (ARIC-NCS). Alzheimers Dement (Amst). 2016; 3:73-82 Epub 2016 May 06
    View PubMed
  651. Iadecola C, Yaffe K, Biller J, Bratzke LC, Faraci FM, Gorelick PB, Gulati M, Kamel H, Knopman DS, Launer LJ, Saczynski JS, Seshadri S, Al Hazzouri AZ. Impact of hypertension on cognitive function: a scientific statement from the American Heart Association Hypertension. 2016; 68: (6)e67-94.
  652. DeGrado TR, Kemp BJ, Pandey MK, Jiang H, Gunderson TM, Linscheid LR, Woodwick AR, McConnell DM, Fletcher JG, Johnson GB, Petersen RC, Knopman DS, Lowe VJ. First PET Imaging Studies With 63Zn-Zinc Citrate in Healthy Human Participants and Patients With Alzheimer Disease. Mol Imaging. 2016; 15 Epub 2016 Dec 09
    View PubMed
  653. Jack CR Jr, Wiste HJ, Weigand SD, Knopman DS, Mielke MM, Vemuri P, Lowe V, Senjem ML, Gunter JL, Reyes D, Machulda MM, Roberts R, Petersen RC. Different definitions of neurodegeneration produce similar amyloid/neurodegeneration biomarker group findings. Brain. 2015 Dec; 138 (Pt 12):3747-59 Epub 2015 Sept 30
    View PubMed
  654. Knopman DS, Jack CR Jr, Lundt ES, Wiste HJ, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, Petersen RC. Role of beta-Amyloidosis and Neurodegeneration in Subsequent Imaging Changes in Mild Cognitive Impairment. JAMA Neurol. 2015 Dec; 72 (12):1475-83
    View PubMed
  655. van Blitterswijk M, Gendron TF, Baker MC, DeJesus-Hernandez M, Finch NA, Brown PH, Daughrity LM, Murray ME, Heckman MG, Jiang J, Lagier-Tourenne C, Edbauer D, Cleveland DW, Josephs KA, Parisi JE, Knopman DS, Petersen RC, Petrucelli L, Boeve BF, Graff-Radford NR, Boylan KB, Dickson DW, Rademakers R. Novel clinical associations with specific C9ORF72 transcripts in patients with repeat expansions in C9ORF72. Acta Neuropathol. 2015 Dec; 130 (6):863-76 Epub 2015 Oct 05
    View PubMed
  656. Knopman DS, Beiser A, Machulda MM, Fields J, Roberts RO, Pankratz VS, Aakre J, Cha RH, Rocca WA, Mielke MM, Boeve BF, Devine S, Ivnik RJ, Au R, Auerbach S, Wolf PA, Seshadri S, Petersen RC. Spectrum of cognition short of dementia: Framingham Heart Study and Mayo Clinic Study of Aging. Neurology. 2015 Nov 10; 85 (19):1712-21 Epub 2015 Oct 09
    View PubMed
  657. Dearborn JL, Schneider AL, Sharrett AR, Mosley TH, Bezerra DC, Knopman DS, Selvin E, Jack CR, Coker LH, Alonso A, Wagenknecht LE, Windham BG, Gottesman RF. Obesity, Insulin Resistance, and Incident Small Vessel Disease on Magnetic Resonance Imaging: Atherosclerosis Risk in Communities Study. Stroke. 2015 Nov; 46 (11):3131-6 Epub 2015 Oct 08
    View PubMed
  658. Mielke MM, Machulda MM, Hagen CE, Edwards KK, Roberts RO, Pankratz VS, Knopman DS, Jack CR Jr, Petersen RC. Performance of the CogState computerized battery in the Mayo Clinic Study on Aging. Alzheimers Dement. 2015 Nov; 11(11):1367-76. Epub 2015 Apr 06.
    View PubMed
  659. Gendron TF, van Blitterswijk M, Bieniek KF, Daughrity LM, Jiang J, Rush BK, Pedraza O, Lucas JA, Murray ME, Desaro P, Robertson A, Overstreet K, Thomas CS, Crook JE, Castanedes-Casey M, Rousseau L, Josephs KA, Parisi JE, Knopman DS, Petersen RC, Boeve BF, Graff-Radford NR, Rademakers R, Lagier-Tourenne C, Edbauer D, Cleveland DW, Dickson DW, Petrucelli L, Boylan KB. Cerebellar c9RAN proteins associate with clinical and neuropathological characteristics of C9ORF72 repeat expansion carriers. Acta Neuropathol. 2015 Oct; 130 (4):559-73 Epub 2015 Sept 08
    View PubMed
  660. Gungor I, Sarro L, Graff-Radford J, Zuk SM, Tosakulwong N, Przybelski SA, Lesnick T, Boeve BF, Ferman TJ, Smith GE, Knopman DS, Filippi M, Petersen RC, Jack CR Jr, Kantarci K. Frequency and topography of cerebral microbleeds in dementia with Lewy bodies compared to Alzheimer's disease. Parkinsonism Relat Disord. 2015 Sep; 21 (9):1101-4 Epub 2015 July 14
    View PubMed
  661. Vassilaki M, Aakre JA, Cha RH, Kremers WK, St Sauver JL, Mielke MM, Geda YE, Machulda MM, Knopman DS, Petersen RC, Roberts RO. Multimorbidity and Risk of Mild Cognitive Impairment. J Am Geriatr Soc. 2015 Sep; 63 (9):1783-90 Epub 2015 Aug 27
    View PubMed
  662. Windham BG, Deere B, Griswold ME, Wang WM, Bezerra DC, Shibata D, Butler K, Knopman D, Gottesman RF, Heiss G, Mosley TH Jr. Small brain lesions and incident stroke and mortality a cohort study. Ann Intern Med. 2015 Jul 7; 163(1):22-31.
    View PubMed
  663. Pottier C, Bieniek KF, Finch N, van de Vorst M, Baker M, Perkersen R, Brown P, Ravenscroft T, van Blitterswijk M, Nicholson AM, DeTure M, Knopman DS, Josephs KA, Parisi JE, Petersen RC, Boylan KB, Boeve BF, Graff-Radford NR, Veltman JA, Gilissen C, Murray ME, Dickson DW, Rademakers R. Whole-genome sequencing reveals important role for TBK1 and OPTN mutations in frontotemporal lobar degeneration without motor neuron disease. Acta Neuropathol. 2015 Jul; 130 (1):77-92 Epub 2015 May 06
    View PubMed
  664. Vemuri P, Senjem ML, Gunter JL, Lundt ES, Tosakulwong N, Weigand SD, Borowski BJ, Bernstein MA, Zuk SM, Lowe VJ, Knopman DS, Petersen RC, Fox NC, Thompson PM, Weiner MW, Jack CR Jr, Alzheimer's Disease Neuroimaging Initiative. Accelerated vs. unaccelerated serial MRI based TBM-SyN measurements for clinical trials in Alzheimer's disease. Neuroimage. 2015 Jun; 113:61-9. Epub 2015 Mar 20.
    View PubMed
  665. Nedelska Z, Schwarz CG, Boeve BF, Lowe VJ, Reid RI, Przybelski SA, Lesnick TG, Gunter JL, Senjem ML, Ferman TJ, Smith GE, Geda YE, Knopman DS, Petersen RC, Jack CR Jr, Kantarci K. White matter integrity in dementia with Lewy bodies: a voxel-based analysis of diffusion tensor imaging. Neurobiol Aging. 2015 Jun; 36 (6):2010-7 Epub 2015 Mar 14
    View PubMed
  666. Snyder HM, Corriveau RA, Craft S, Faber JE, Greenberg SM, Knopman D, Lamb BT, Montine TJ, Nedergaard M, Schaffer CB, Schneider JA, Wellington C, Wilcock DM, Zipfel GJ, Zlokovic B, Bain LJ, Bosetti F, Galis ZS, Koroshetz W, Carrillo MC. Vascular contributions to cognitive impairment and dementia including Alzheimer's disease. Alzheimers Dement. 2015 Jun; 11 (6):710-7 Epub 2014 Dec 12
    View PubMed
  667. Ayton S, Faux NG, Bush AI, Alzheimer's Disease Neuroimaging Initiative, Petersen R, Jack CR Jr, Bernstein M, Jones D, Kantarci K, Knopman D, Graff-Radford NR. Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE. Nat Commun. 2015 May 19; 6:6760
    View PubMed
  668. Roberts RO, Cha RH, Mielke MM, Geda YE, Boeve BF, Machulda MM, Knopman DS, Petersen RC. Risk and protective factors for cognitive impairment in persons aged 85 years and older. Neurology. 2015 May 5; 84 (18):1854-61 Epub 2015 Apr 08
    View PubMed
  669. Whitwell JL, Boeve BF, Weigand SD, Senjem ML, Gunter JL, Baker MC, DeJesus-Hernandez M, Knopman DS, Wszolek ZK, Petersen RC, Rademakers R, Jack CR Jr, Josephs KA. Brain atrophy over time in genetic and sporadic frontotemporal dementia: a study of 198 serial magnetic resonance images. Eur J Neurol. 2015 May; 22 (5):745-52 Epub 2015 Feb 12
    View PubMed
  670. Jack CR Jr, Wiste HJ, Weigand SD, Knopman DS, Vemuri P, Mielke MM, Lowe V, Senjem ML, Gunter JL, Machulda MM, Gregg BE, Pankratz VS, Rocca WA, Petersen RC. Age, Sex, and APOE epsilon4 Effects on Memory, Brain Structure, and beta-Amyloid Across the Adult Life Span. JAMA Neurol. 2015 May; 72 (5):511-9
    View PubMed
  671. Murray ME, Lowe VJ, Graff-Radford NR, Liesinger AM, Cannon A, Przybelski SA, Rawal B, Parisi JE, Petersen RC, Kantarci K, Ross OA, Duara R, Knopman DS, Jack CR Jr, Dickson DW. Clinicopathologic and 11C-Pittsburgh compound B implications of Thal amyloid phase across the Alzheimer's disease spectrum. Brain. 2015 May; 138 (Pt 5):1370-81 Epub 2015 Mar 23
    View PubMed
  672. Deal JA, Sharrett AR, Albert MS, Coresh J, Mosley TH, Knopman D, Wruck LM, Lin FR. Hearing impairment and cognitive decline: a pilot study conducted within the atherosclerosis risk in communities neurocognitive study. Am J Epidemiol. 2015 May 1; 181(9):680-90.
    View PubMed
  673. Debette S, Ibrahim Verbaas CA, Bressler J, Schuur M, Smith A, Bis JC, Davies G, Wolf C, Gudnason V, Chibnik LB, Yang Q, deStefano AL, de Quervain DJ, Srikanth V, Lahti J, Grabe HJ, Smith JA, Priebe L, Yu L, Karbalai N, Hayward C, Wilson JF, Campbell H, Petrovic K, Fornage M, Chauhan G, Yeo R, Boxall R, Becker J, Stegle O, Mather KA, Chouraki V, Sun Q, Rose LM, Resnick S, Oldmeadow C, Kirin M, Wright AF, Jonsdottir MK, Au R, Becker A, Amin N, Nalls MA, Turner ST, Kardia SL, Oostra B, Windham G, Coker LH, Zhao W, Knopman DS, Heiss G, Griswold ME, Gottesman RF, Vitart V, Hastie ND, Zgaga L, Rudan I, Polasek O, Holliday EG, Schofield P, Choi SH, Tanaka T, An Y, Perry RT, Kennedy RE, Sale MM, Wang J, Wadley VG, Liewald DC, Ridker PM, Gow AJ, Pattie A, Starr JM, Porteous D, Liu X, Thomson R, Armstrong NJ, Eiriksdottir G, Assareh AA, Kochan NA, Widen E, Palotie A, Hsieh YC, Eriksson JG, Vogler C, van Swieten JC, Shulman JM, Beiser A, Rotter J, Schmidt CO, Hoffmann W, Nothen MM, Ferrucci L, Attia J, Uitterlinden AG, Amouyel P, Dartigues JF, Amieva H, Raikkonen K, Garcia M, Wolf PA, Hofman A, Longstreth WT Jr, Psaty BM, Boerwinkle E, DeJager PL, Sachdev PS, Schmidt R, Breteler MM, Teumer A, Lopez OL, Cichon S, Chasman DI, Grodstein F, Muller-Myhsok B, Tzourio C, Papassotiropoulos A, Bennett DA, Ikram MA, Deary IJ, van Duijn CM, Launer L, Fitzpatrick AL, Seshadri S, Mosley TH Jr, Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. Biol Psychiatry. 2015 Apr 15; 77 (8):749-63 Epub 2014 Nov 25
    View PubMed
  674. Brown CH 4th, Sharrett AR, Coresh J, Schneider AL, Alonso A, Knopman DS, Mosley TH, Gottesman RF. Association of hospitalization with long-term cognitive and brain MRI changes in the ARIC cohort. Neurology. 2015 Apr 7; 84 (14):1443-53 Epub 2015 Mar 11
    View PubMed
  675. Pankratz VS, Roberts RO, Mielke MM, Knopman DS, Jack CR Jr, Geda YE, Rocca WA, Petersen RC. Predicting the risk of mild cognitive impairment in the Mayo Clinic Study of Aging. Neurology. 2015 Apr 7; 84 (14):1433-42 Epub 2015 Mar 18
    View PubMed
  676. Verhaaren BF, Debette S, Bis JC, Smith JA, Ikram MK, Adams HH, Beecham AH, Rajan KB, Lopez LM, Barral S, van Buchem MA, van der Grond J, Smith AV, Hegenscheid K, Aggarwal NT, de Andrade M, Atkinson EJ, Beekman M, Beiser AS, Blanton SH, Boerwinkle E, Brickman AM, Bryan RN, Chauhan G, Chen CP, Chouraki V, de Craen AJ, Crivello F, Deary IJ, Deelen J, De Jager PL, Dufouil C, Elkind MS, Evans DA, Freudenberger P, Gottesman RF, Guethnason V, Habes M, Heckbert SR, Heiss G, Hilal S, Hofer E, Hofman A, Ibrahim-Verbaas CA, Knopman DS, Lewis CE, Liao J, Liewald DC, Luciano M, van der Lugt A, Martinez OO, Mayeux R, Mazoyer B, Nalls M, Nauck M, Niessen WJ, Oostra BA, Psaty BM, Rice KM, Rotter JI, von Sarnowski B, Schmidt H, Schreiner PJ, Schuur M, Sidney SS, Sigurdsson S, Slagboom PE, Stott DJ, van Swieten JC, Teumer A, Toglhofer AM, Traylor M, Trompet S, Turner ST, Tzourio C, Uh HW, Uitterlinden AG, Vernooij MW, Wang JJ, Wong TY, Wardlaw JM, Windham BG, Wittfeld K, Wolf C, Wright CB, Yang Q, Zhao W, Zijdenbos A, Jukema JW, Sacco RL, Kardia SL, Amouyel P, Mosley TH, Longstreth WT Jr, DeCarli CC, van Duijn CM, Schmidt R, Launer LJ, Grabe HJ, Seshadri SS, Ikram MA, Fornage M. Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI. Circ Cardiovasc Genet. 2015 Apr; 8 (2):398-409 Epub 2015 Feb 07
    View PubMed
  677. Chauhan G, Adams HHH, Bis JC, Weinstein G, Yu L, Toglhofer AM, Smith AV, van der Lee SJ, Gottesman RF, Thomson R, Wang J, Yang Q, Niessen WJ, Lopez OL, Becker JT, Phan TG, Beare RJ, Arfanakis K, Fleischman D, Vernooij MW, Mazoyer B, Schmidt H, Srikanth V, Knopman DS, Jack CR Jr, Amouyel P, Hofman A, DeCarli C, Tzourio C, van Duijn CM, Bennett DA, Schmidt R, Longstreth WT Jr, Mosley TH, Fornage M, Launer LJ, Seshadri S, Ikram MA, Debette S. Association of Alzheimer's disease GWAS loci with MRI markers of brain aging. Neurobiol Aging. 2015 Apr; 36 (4):1765.e7-1765.e16 Epub 2015 Jan 06
    View PubMed
  678. Pink A, Stokin GB, Bartley MM, Roberts RO, Sochor O, Machulda MM, Krell-Roesch J, Knopman DS, Acosta JI, Christianson TJ, Pankratz VS, Mielke MM, Petersen RC, Geda YE. Neuropsychiatric symptoms, APOE epsilon4, and the risk of incident dementia: a population-based study. Neurology. 2015 Mar 3; 84 (9):935-43 Epub 2015 Feb 04
    View PubMed
  679. Zhang B, Ferman TJ, Boeve BF, Smith GE, Maroney-Smith M, Spychalla AJ, Knopman DS, Jack CR Jr, Petersen RC, Kantarci K. MRS in mild cognitive impairment: early differentiation of dementia with Lewy bodies and Alzheimer's disease. J Neuroimaging. 2015 Mar-Apr; 25 (2):269-274 Epub 2014 July 15
    View PubMed
  680. Vemuri P, Lesnick TG, Przybelski SA, Knopman DS, Preboske GM, Kantarci K, Raman MR, Machulda MM, Mielke MM, Lowe VJ, Senjem ML, Gunter JL, Rocca WA, Roberts RO, Petersen RC, Jack CR Jr. Vascular and amyloid pathologies are independent predictors of cognitive decline in normal elderly. Brain. 2015 Mar; 138 (Pt 3):761-71 Epub 2015 Jan 15
    View PubMed
  681. Power MC, Deal JA, Sharrett AR, Jack CR Jr, Knopman D, Mosley TH, Gottesman RF. Smoking and white matter hyperintensity progression: the ARIC-MRI Study. Neurology. 2015 Feb 24; 84 (8):841-8 Epub 2015 Jan 28
    View PubMed
  682. Davies G, Armstrong N, Bis JC, Bressler J, Chouraki V, Giddaluru S, Hofer E, Ibrahim-Verbaas CA, Kirin M, Lahti J, van der Lee SJ, Le Hellard S, Liu T, Marioni RE, Oldmeadow C, Postmus I, Smith AV, Smith JA, Thalamuthu A, Thomson R, Vitart V, Wang J, Yu L, Zgaga L, Zhao W, Boxall R, Harris SE, Hill WD, Liewald DC, Luciano M, Adams H, Ames D, Amin N, Amouyel P, Assareh AA, Au R, Becker JT, Beiser A, Berr C, Bertram L, Boerwinkle E, Buckley BM, Campbell H, Corley J, De Jager PL, Dufouil C, Eriksson JG, Espeseth T, Faul JD, Ford I, Gottesman RF, Griswold ME, Gudnason V, Harris TB, Heiss G, Hofman A, Holliday EG, Huffman J, Kardia SL, Kochan N, Knopman DS, Kwok JB, Lambert JC, Lee T, Li G, Li SC, Loitfelder M, Lopez OL, Lundervold AJ, Lundqvist A, Mather KA, Mirza SS, Nyberg L, Oostra BA, Palotie A, Papenberg G, Pattie A, Petrovic K, Polasek O, Psaty BM, Redmond P, Reppermund S, Rotter JI, Schmidt H, Schuur M, Schofield PW, Scott RJ, Steen VM, Stott DJ, van Swieten JC, Taylor KD, Trollor J, Trompet S, Uitterlinden AG, Weinstein G, Widen E, Windham BG, Jukema JW, Wright AF, Wright MJ, Yang Q, Amieva H, Attia JR, Bennett DA, Brodaty H, de Craen AJ, Hayward C, Ikram MA, Lindenberger U, Nilsson LG, Porteous DJ, Raikkonen K, Reinvang I, Rudan I, Sachdev PS, Schmidt R, Schofield PR, Srikanth V, Starr JM, Turner ST, Weir DR, Wilson JF, van Duijn C, Launer L, Fitzpatrick AL, Seshadri S, Mosley TH Jr, Deary IJ, Generation Scotland. Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949). Mol Psychiatry. 2015 Feb; 20 (2):183-92 Epub 2015 Feb 03
    View PubMed
  683. Knopman DS, Griswold ME, Lirette ST, Gottesman RF, Kantarci K, Sharrett AR, Jack CR Jr, Graff-Radford J, Schneider AL, Windham BG, Coker LH, Albert MS, Mosley TH Jr, ARIC Neurocognitive Investigators. Vascular imaging abnormalities and cognition: mediation by cortical volume in nondemented individuals: atherosclerosis risk in communities-neurocognitive study. Stroke. 2015 Feb; 46 (2):433-40 Epub 2015 Jan 06
    View PubMed
  684. Roberts RO, Aakre JA, Cha RH, Kremers WK, Mielke MM, Velgos SN, Geda YE, Knopman DS, Petersen RC. Association of Pancreatic Polypeptide with Mild Cognitive Impairment Varies by APOE epsilon4 Allele. Front Aging Neurosci. 2015; 7:172 Epub 2015 Sept 08
    View PubMed
  685. Vassilaki M, Cha RH, Aakre JA, Therneau TM, Geda YE, Mielke MM, Knopman DS, Petersen RC, Roberts RO. Mortality in mild cognitive impairment varies by subtype, sex, and lifestyle factors: the Mayo Clinic Study of Aging. J Alzheimers Dis. 2015; 45 (4):1237-45
    View PubMed
  686. Schneider AL, Sharrett AR, Gottesman RF, Coresh J, Coker L, Wruck L, Selnes OA, Deal J, Knopman D, Mosley TH. Normative data for 8 neuropsychological tests in older blacks and whites from the atherosclerosis risk in communities (ARIC) study. Alzheimer Dis Assoc Disord. 2015 Jan-Mar; 29 (1):32-44
    View PubMed
  687. Nedelska Z, Ferman TJ, Boeve BF, Przybelski SA, Lesnick TG, Murray ME, Gunter JL, Senjem ML, Vemuri P, Smith GE, Geda YE, Graff-Radford J, Knopman DS, Petersen RC, Parisi JE, Dickson DW, Jack CR Jr, Kantarci K. Pattern of brain atrophy rates in autopsy-confirmed dementia with Lewy bodies. Neurobiol Aging. 2015 Jan; 36 (1):452-61 Epub 2014 July 15
    View PubMed
  688. Pakhomov SV, Jones DT, Knopman DS. Language networks associated with computerized semantic indices. Neuroimage. 2015 Jan 1; 104:125-37 Epub 2014 Oct 12
    View PubMed
  689. Zhao Q, Roberts RO, Ding D, Cha R, Guo Q, Meng H, Luo J, Machulda MM, Shane Pankratz V, Wang B, Christianson TJ, Aakre JA, Knopman DS, Boeve BF, Hong Z, Petersen RC, Shanghai Aging Study (SAS)//Mayo Clinic Study of Aging (MCSA). Diabetes is Associated with Worse Executive Function in Both Eastern and Western Populations: Shanghai Aging Study and Mayo Clinic Study of Aging. J Alzheimers Dis. 2015; 47 (1):167-76
    View PubMed
  690. Gottesman RF, Fornage M, Knopman DS, Mosley TH. Brain aging in African-Americans: the atherosclerosis risk in communities (aric) experience. Curr Alzheimer Res. 2015; 12(7):607-13.
    View PubMed
  691. Murray ME, Przybelski SA, Lesnick TG, Liesinger AM, Spychalla A, Zhang B, Gunter JL, Parisi JE, Boeve BF, Knopman DS, Petersen RC, Jack CR Jr, Dickson DW, Kantarci K. Early Alzheimer's disease neuropathology detected by proton MR spectroscopy. J Neurosci. 2014 Dec 3; 34 (49):16247-55
    View PubMed
  692. Crary JF, Trojanowski JQ, Schneider JA, Abisambra JF, Abner EL, Alafuzoff I, Arnold SE, Attems J, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Gearing M, Grinberg LT, Hof PR, Hyman BT, Jellinger K, Jicha GA, Kovacs GG, Knopman DS, Kofler J, Kukull WA, Mackenzie IR, Masliah E, McKee A, Montine TJ, Murray ME, Neltner JH, Santa-Maria I, Seeley WW, Serrano-Pozo A, Shelanski ML, Stein T, Takao M, Thal DR, Toledo JB, Troncoso JC, Vonsattel JP, White CL, Wisniewski T, Woltjer RL, Yamada M, Nelson PT. Primary age-related tauopathy (part): a common pathology associated with human aging. Acta Neuropathol (Berl). 2014 Dec; 128(6):755-66.
  693. Kantarci K, Schwarz CG, Reid RI, Przybelski SA, Lesnick TG, Zuk SM, Senjem ML, Gunter JL, Lowe V, Machulda MM, Knopman DS, Petersen RC, Jack CR Jr. White matter integrity determined with diffusion tensor imaging in older adults without dementia: influence of amyloid load and neurodegeneration. JAMA Neurol. 2014 Dec; 71 (12):1547-54
    View PubMed
  694. Crary JF, Trojanowski JQ, Schneider JA, Abisambra JF, Abner EL, Alafuzoff I, Arnold SE, Attems J, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Gearing M, Grinberg LT, Hof PR, Hyman BT, Jellinger K, Jicha GA, Kovacs GG, Knopman DS, Kofler J, Kukull WA, Mackenzie IR, Masliah E, McKee A, Montine TJ, Murray ME, Neltner JH, Santa-Maria I, Seeley WW, Serrano-Pozo A, Shelanski ML, Stein T, Takao M, Thal DR, Toledo JB, Troncoso JC, Vonsattel JP, White CL 3rd, Wisniewski T, Woltjer RL, Yamada M, Nelson PT. Primary age-related tauopathy (PART): a common pathology associated with human aging. Acta Neuropathol. 2014 Dec; 128 (6):755-66 Epub 2014 Oct 28
    View PubMed
  695. Mielke MM, Weigand SD, Wiste HJ, Vemuri P, Machulda MM, Knopman DS, Lowe V, Roberts RO, Kantarci K, Rocca WA, Jack CR Jr, Petersen RC. Independent comparison of CogState computerized testing and a standard cognitive battery with neuroimaging. Alzheimers Dement. 2014 Nov; 10 (6):779-89 Epub 2014 Nov 15
    View PubMed
  696. Gottesman RF, Schneider AL, Albert M, Alonso A, Bandeen-Roche K, Coker L, Coresh J, Knopman D, Power MC, Rawlings A, Sharrett AR, Wruck LM, Mosley TH. Midlife hypertension and 20-year cognitive change: the atherosclerosis risk in communities neurocognitive study. JAMA Neurol. 2014 Oct; 71 (10):1218-27
    View PubMed
  697. van Blitterswijk M, Mullen B, Heckman MG, Baker MC, DeJesus-Hernandez M, Brown PH, Murray ME, Hsiung GY, Stewart H, Karydas AM, Finger E, Kertesz A, Bigio EH, Weintraub S, Mesulam M, Hatanpaa KJ, White CL 3rd, Neumann M, Strong MJ, Beach TG, Wszolek ZK, Lippa C, Caselli R, Petrucelli L, Josephs KA, Parisi JE, Knopman DS, Petersen RC, Mackenzie IR, Seeley WW, Grinberg LT, Miller BL, Boylan KB, Graff-Radford NR, Boeve BF, Dickson DW, Rademakers R. Ataxin-2 as potential disease modifier in C9ORF72 expansion carriers. Neurobiol Aging. 2014 Oct; 35 (10):2421.e13-7 Epub 2014 May 02
    View PubMed
  698. Fargo KN, Aisen P, Albert M, Au R, Corrada MM, DeKosky S, Drachman D, Fillit H, Gitlin L, Haas M, Herrup K, Kawas C, Khachaturian AS, Khachaturian ZS, Klunk W, Knopman D, Kukull WA, Lamb B, Logsdon RG, Maruff P, Mesulam M, Mobley W, Mohs R, Morgan D, Nixon RA, Paul S, Petersen R, Plassman B, Potter W, Reiman E, Reisberg B, Sano M, Schindler R, Schneider LS, Snyder PJ, Sperling RA, Yaffe K, Bain LJ, Thies WH, Carrillo MC, Alzheimer's Association National Plan Milestone Workgroup. 2014 Report on the Milestones for the US National Plan to Address Alzheimer's Disease. Alzheimers Dement. 2014 Oct; 10 (5 Suppl):S430-52
    View PubMed
  699. Jack CR Jr, Wiste HJ, Weigand SD, Rocca WA, Knopman DS, Mielke MM, Lowe VJ, Senjem ML, Gunter JL, Preboske GM, Pankratz VS, Vemuri P, Petersen RC. Age-specific population frequencies of cerebral beta-amyloidosis and neurodegeneration among people with normal cognitive function aged 50-89 years: a cross-sectional study. Lancet Neurol. 2014 Oct; 13 (10):997-1005 Epub 2014 Sept 04
    View PubMed
  700. Knopman DS, Petersen RC. Mild cognitive impairment and mild dementia: a clinical perspective. Mayo Clin Proc. 2014 Oct; 89 (10):1452-9
    View PubMed
  701. Gunter J, Senjem M, Donohue MC, Jacqmin-Gadda H, Le Goff M, Thomas RG, Raman R, Gamst AC, Beckett LA, Jack CR Jr, Weiner MW, Dartigues JF, Aisen PS, Alzheimer's Disease Neuroimaging Initiative. Estimating long-term multivariate progression from short-term data. Alzheimers Dement. 2014 Oct; 10 (5 Suppl):S400-10 Epub 2014 Mar 20
    View PubMed
  702. van Blitterswijk M, Mullen B, Wojtas A, Heckman MG, Diehl NN, Baker MC, DeJesus-Hernandez M, Brown PH, Murray ME, Hsiung GY, Stewart H, Karydas AM, Finger E, Kertesz A, Bigio EH, Weintraub S, Mesulam M, Hatanpaa KJ, White CL 3rd, Neumann M, Strong MJ, Beach TG, Wszolek ZK, Lippa C, Caselli R, Petrucelli L, Josephs KA, Parisi JE, Knopman DS, Petersen RC, Mackenzie IR, Seeley WW, Grinberg LT, Miller BL, Boylan KB, Graff-Radford NR, Boeve BF, Dickson DW, Rademakers R. Genetic modifiers in carriers of repeat expansions in the C9ORF72 gene. Mol Neurodegener. 2014 Sep 20; 9:38 Epub 2014 Sept 20
    View PubMed
  703. Russo G, Russo MJ, Buyatti D, Chrem P, Bagnati P, Fernandez Suarez M, Campos J, Cohen G, Amengual A, Allegri RF, Knopman DS. Utility of the Spanish version of the FTLD-modified CDR in the diagnosis and staging in frontotemporal lobar degeneration. J Neurol Sci. 2014 Sep 15; 344(1-2):63-8. Epub 2014 Jun 20.
    View PubMed
  704. Knopman DS, Jack CR Jr, Wiste HJ, Lundt ES, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Roberts RO, Boeve BF, Petersen RC. 18F-fluorodeoxyglucose positron emission tomography, aging, and apolipoprotein E genotype in cognitively normal persons. Neurobiol Aging. 2014 Sep; 35 (9):2096-106 Epub 2014 Mar 11
    View PubMed
  705. Graff-Radford J, Murray ME, Lowe VJ, Boeve BF, Ferman TJ, Przybelski SA, Lesnick TG, Senjem ML, Gunter JL, Smith GE, Knopman DS, Jack CR Jr, Dickson DW, Petersen RC, Kantarci K. Dementia with Lewy bodies: basis of cingulate island sign. Neurology. 2014 Aug 26; 83 (9):801-9 Epub 2014 July 23
    View PubMed
  706. Montine TJ, Koroshetz WJ, Babcock D, Dickson DW, Galpern WR, Glymour MM, Greenberg SM, Hutton ML, Knopman DS, Kuzmichev AN, Manly JJ, Marder KS, Miller BL, Phelps CH, Seeley WW, Sieber BA, Silverberg NB, Sutherland M, Torborg CL, Waddy SP, Zlokovic BV, Corriveau RA, ADRD 2013 Conference Organizing Committee. Recommendations of the Alzheimer's disease-related dementias conference. Neurology. 2014 Aug 26; 83 (9):851-60 Epub 2014 July 30
    View PubMed
  707. Vemuri P, Lesnick TG, Przybelski SA, Machulda M, Knopman DS, Mielke MM, Roberts RO, Geda YE, Rocca WA, Petersen RC, Jack CR Jr. Association of lifetime intellectual enrichment with cognitive decline in the older population. JAMA Neurol. 2014 Aug; 71 (8):1017-24
    View PubMed
  708. Ferrari R, Hernandez DG, Nalls MA, Rohrer JD, Ramasamy A, Kwok JB, Dobson-Stone C, Brooks WS, Schofield PR, Halliday GM, Hodges JR, Piguet O, Bartley L, Thompson E, Haan E, Hernandez I, Ruiz A, Boada M, Borroni B, Padovani A, Cruchaga C, Cairns NJ, Benussi L, Binetti G, Ghidoni R, Forloni G, Galimberti D, Fenoglio C, Serpente M, Scarpini E, Clarimon J, Lleo A, Blesa R, Waldo ML, Nilsson K, Nilsson C, Mackenzie IR, Hsiung GY, Mann DM, Grafman J, Morris CM, Attems J, Griffiths TD, McKeith IG, Thomas AJ, Pietrini P, Huey ED, Wassermann EM, Baborie A, Jaros E, Tierney MC, Pastor P, Razquin C, Ortega-Cubero S, Alonso E, Perneczky R, Diehl-Schmid J, Alexopoulos P, Kurz A, Rainero I, Rubino E, Pinessi L, Rogaeva E, St George-Hyslop P, Rossi G, Tagliavini F, Giaccone G, Rowe JB, Schlachetzki JC, Uphill J, Collinge J, Mead S, Danek A, Van Deerlin VM, Grossman M, Trojanowski JQ, van der Zee J, Deschamps W, Van Langenhove T, Cruts M, Van Broeckhoven C, Cappa SF, Le Ber I, Hannequin D, Golfier V, Vercelletto M, Brice A, Nacmias B, Sorbi S, Bagnoli S, Piaceri I, Nielsen JE, Hjermind LE, Riemenschneider M, Mayhaus M, Ibach B, Gasparoni G, Pichler S, Gu W, Rossor MN, Fox NC, Warren JD, Spillantini MG, Morris HR, Rizzu P, Heutink P, Snowden JS, Rollinson S, Richardson A, Gerhard A, Bruni AC, Maletta R, Frangipane F, Cupidi C, Bernardi L, Anfossi M, Gallo M, Conidi ME, Smirne N, Rademakers R, Baker M, Dickson DW, Graff-Radford NR, Petersen RC, Knopman D, Josephs KA, Boeve BF, Parisi JE, Seeley WW, Miller BL, Karydas AM, Rosen H, van Swieten JC, Dopper EG, Seelaar H, Pijnenburg YA, Scheltens P, Logroscino G, Capozzo R, Novelli V, Puca AA, Franceschi M, Postiglione A, Milan G, Sorrentino P, Kristiansen M, Chiang HH, Graff C, Pasquier F, Rollin A, Deramecourt V, Lebert F, Kapogiannis D, Ferrucci L, Pickering-Brown S, Singleton AB, Hardy J, Momeni P. Frontotemporal dementia and its subtypes: a genome-wide association study. Lancet Neurol. 2014 Jul; 13 (7):686-99
    View PubMed
  709. Jung Y, Dickson DW, Murray ME, Whitwell JL, Knopman DS, Boeve BF, Jack CR Jr, Parisi JE, Petersen RC, Josephs KA. TDP-43 in Alzheimer's disease is not associated with clinical FTLD or Parkinsonism. J Neurol. 2014 Jul; 261 (7):1344-8 Epub 2014 Apr 24
    View PubMed
  710. Boxer AL, Lang AE, Grossman M, Knopman DS, Miller BL, Schneider LS, Doody RS, Lees A, Golbe LI, Williams DR, Corvol JC, Ludolph A, Burn D, Lorenzl S, Litvan I, Roberson ED, Hoglinger GU, Koestler M, Jack CR Jr, Van Deerlin V, Randolph C, Lobach IV, Heuer HW, Gozes I, Parker L, Whitaker S, Hirman J, Stewart AJ, Gold M, Morimoto BH, AL-108-231 Investigators. Davunetide in patients with progressive supranuclear palsy: a randomised, double-blind, placebo-controlled phase 2/3 trial. Lancet Neurol. 2014 Jul; 13 (7):676-85 Epub 2014 May 27
    View PubMed
  711. Raman MR, Preboske GM, Przybelski SA, Gunter JL, Senjem ML, Vemuri P, Murphy MC, Murray ME, Boeve BF, Knopman DS, Petersen RC, Parisi JE, Dickson DW, Jack CR Jr, Kantarci K. Antemortem MRI findings associated with microinfarcts at autopsy. Neurology. 2014 Jun 3; 82 (22):1951-8 Epub 2014 May 02
    View PubMed
  712. Lowe VJ, Weigand SD, Senjem ML, Vemuri P, Jordan L, Kantarci K, Boeve B, Jack CR Jr, Knopman D, Petersen RC. Association of hypometabolism and amyloid levels in aging, normal subjects. Neurology. 2014 Jun 3; 82 (22):1959-67 Epub 2014 May 02
    View PubMed
  713. Flanagan EP, Knopman DS, Keegan BM. Dementia in MS complicated by coexistent Alzheimer disease: Diagnosis premortem and postmortem. Neurol Clin Pract. 2014 Jun; 4 (3):226-230
    View PubMed
  714. Graff-Radford J, Boeve BF, Murray ME, Ferman TJ, Tosakulwong N, Lesnick TG, Maroney-Smith M, Senjem ML, Gunter J, Smith GE, Knopman DS, Jack CR Jr, Dickson DW, Petersen RC, Kantarci K. Regional proton magnetic resonance spectroscopy patterns in dementia with Lewy bodies. Neurobiol Aging. 2014 Jun; 35 (6):1483-90 Epub 2014 Jan 08
    View PubMed
  715. Nicholson AM, Finch NA, Thomas CS, Wojtas A, Rutherford NJ, Mielke MM, Roberts RO, Boeve BF, Knopman DS, Petersen RC, Rademakers R. Progranulin protein levels are differently regulated in plasma and CSF. Neurology. 2014 May 27; 82 (21):1871-8 Epub 2014 Apr 25
    View PubMed
  716. Jack CR Jr, Wiste HJ, Knopman DS, Vemuri P, Mielke MM, Weigand SD, Senjem ML, Gunter JL, Lowe V, Gregg BE, Pankratz VS, Petersen RC. Rates of beta-amyloid accumulation are independent of hippocampal neurodegeneration. Neurology. 2014 May 6; 82 (18):1605-12 Epub 2014 Apr 04
    View PubMed
  717. Roberts RO, Knopman DS, Cha RH, Mielke MM, Pankratz VS, Boeve BF, Kantarci K, Geda YE, Jack CR Jr, Petersen RC, Lowe VJ. Diabetes and elevated hemoglobin A1c levels are associated with brain hypometabolism but not amyloid accumulation. J Nucl Med. 2014 May; 55 (5):759-64 Epub 2014 Mar 20
    View PubMed
  718. Gottesman RF, Rawlings AM, Sharrett AR, Albert M, Alonso A, Bandeen-Roche K, Coker LH, Coresh J, Couper DJ, Griswold ME, Heiss G, Knopman DS, Patel MD, Penman AD, Power MC, Selnes OA, Schneider ALC, Wagenknecht LE, Windham BG, Wruck LM, Mosley TH. Impact of differential attrition on the association of education with cognitive change over 20 years of follow-up. Am J Epidemiol. 2014 Apr 15; 179(8):956-66.
    View PubMed
  719. Roberts RO, Knopman DS, Przybelski SA, Mielke MM, Kantarci K, Preboske GM, Senjem ML, Pankratz VS, Geda YE, Boeve BF, Ivnik RJ, Rocca WA, Petersen RC, Jack CR Jr. Association of type 2 diabetes with brain atrophy and cognitive impairment. Neurology. 2014 Apr 1; 82 (13):1132-41 Epub 2014 Mar 19
    View PubMed
  720. Hanff TC, Sharrett AR, Mosley TH, Shibata D, Knopman DS, Klein R, Klein BE, Gottesman RF. Retinal microvascular abnormalities predict progression of brain microvascular disease: an atherosclerosis risk in communities magnetic resonance imaging study. Stroke. 2014 Apr; 45 (4):1012-7 Epub 2014 Feb 18
    View PubMed
  721. van Blitterswijk M, Mullen B, Nicholson AM, Bieniek KF, Heckman MG, Baker MC, DeJesus-Hernandez M, Finch NA, Brown PH, Murray ME, Hsiung GY, Stewart H, Karydas AM, Finger E, Kertesz A, Bigio EH, Weintraub S, Mesulam M, Hatanpaa KJ, White CL 3rd, Strong MJ, Beach TG, Wszolek ZK, Lippa C, Caselli R, Petrucelli L, Josephs KA, Parisi JE, Knopman DS, Petersen RC, Mackenzie IR, Seeley WW, Grinberg LT, Miller BL, Boylan KB, Graff-Radford NR, Boeve BF, Dickson DW, Rademakers R. TMEM106B protects C9ORF72 expansion carriers against frontotemporal dementia. Acta Neuropathol. 2014 Mar; 127 (3):397-406 Epub 2014 Jan 03
    View PubMed
  722. Parsaik AK, Singh B, Roberts RO, Pankratz S, Edwards KK, Geda YE, Gharib H, Boeve BF, Knopman DS, Petersen RC. Hypothyroidism and risk of mild cognitive impairment in elderly persons: a population-based study. JAMA Neurol. 2014 Feb; 71(2):201-7.
    View PubMed
  723. Roberts RO, Knopman DS, Mielke MM, Cha RH, Pankratz VS, Christianson TJ, Geda YE, Boeve BF, Ivnik RJ, Tangalos EG, Rocca WA, Petersen RC. Higher risk of progression to dementia in mild cognitive impairment cases who revert to normal. Neurology. 2014 Jan 28; 82 (4):317-25 Epub 2013 Dec 18
    View PubMed
  724. Mielke MM, Savica R, Wiste HJ, Weigand SD, Vemuri P, Knopman DS, Lowe VJ, Roberts RO, Machulda MM, Geda YE, Petersen RC, Jack CR Jr. Head trauma and in vivo measures of amyloid and neurodegeneration in a population-based study. Neurology. 2014 Jan 07; 82(1):70-6. Epub 2013 Dec 26.
    View PubMed
  725. Schneider ALC, Lutsey PL, Alonso A, Gottesman RF, Sharrett AR, Carson KA, Gross M, Post WS, Knopman DS, Mosley TH, Michos ED. Vitamin D and cognitive function and dementia risk in a biracial cohort: The ARIC Brain MRI Study. Eur J Neurol. 2014; 21(9):1211-e70.
    View PubMed
  726. Mayeda ER, Haan MN, Neuhaus J, Yaffe K, Knopman DS, Sharrett AR, Griswold ME, Mosley TH. Type 2 diabetes and cognitive decline over 14 years in middle-aged African Americans and whites: the aric brain mri study. Neuroepidemiology. 2014; 43(3-4):220-7.
    View PubMed
  727. Knopman DS, Griswold ME, Lirette ST, Gottesman RF, Kantarci K, Sharrett AR, Jack CR Jr, Graff-Radford J, Schneider ALC, Windham BG, Coker LH, Albert MS, Mosley TH Jr, Coresh J, Roche KB, Selnes OA, McKhann G, Alonso A, Folsom AR, Eckfeldt J, Wagenknecht LE, Heiss G, Couper D, Wruck L. Vascular Imaging abnormalities and cognition: Mediation by cortical volume in nondemented individuals: Atherosclerosis risk in communities-neurocognitive study. Stroke. 2014; 46(2):433-40.
  728. Roberts RO, Knopman DS, Geda YE, Cha RH, Pankratz VS, Baertlein L, Boeve BF, Tangalos EG, Ivnik RJ, Mielke MM, Petersen RC. Association of diabetes with amnestic and nonamnestic mild cognitive impairment. Alzheimers Dement. 2014 Jan; 10 (1):18-26 Epub 2013 Apr 03
    View PubMed
  729. Ferman TJ, Smith GE, Kantarci K, Boeve BF, Pankratz VS, Dickson DW, Graff-Radford NR, Wszolek Z, Van Gerpen J, Uitti R, Pedraza O, Murray ME, Aakre J, Parisi J, Knopman DS, Petersen RC. Nonamnestic mild cognitive impairment progresses to dementia with Lewy bodies. Neurology. 2013 Dec 3; 81 (23):2032-8 Epub 2013 Nov 08
    View PubMed
  730. Locke DE, Dueck AC, Stonnington CM, Knopman DS, Geda YE, Caselli RJ. Depressive symptoms in healthy apolipoprotein E epsilon4 carriers and noncarriers: a longitudinal study. J Clin Psychiatry. 2013 Dec; 74 (12):1256-61
    View PubMed
  731. Jack CR Jr, Wiste HJ, Weigand SD, Knopman DS, Lowe V, Vemuri P, Mielke MM, Jones DT, Senjem ML, Gunter JL, Gregg BE, Pankratz VS, Petersen RC. Amyloid-first and neurodegeneration-first profiles characterize incident amyloid PET positivity. Neurology. 2013 Nov 12; 81 (20):1732-40 Epub 2013 Oct 16
    View PubMed
  732. Murray ME, Ferman TJ, Boeve BF, Przybelski SA, Lesnick TG, Liesinger AM, Senjem ML, Gunter JL, Preboske GM, Lowe VJ, Vemuri P, Dugger BN, Knopman DS, Smith GE, Parisi JE, Silber MH, Graff-Radford NR, Petersen RC, Jack CR Jr, Dickson DW, Kantarci K. MRI and pathology of REM sleep behavior disorder in dementia with Lewy bodies. Neurology. 2013 Nov 5; 81 (19):1681-9 Epub 2013 Oct 09
    View PubMed
  733. Roberts R, Knopman DS. Classification and epidemiology of MCI. Clin Geriatr Med. 2013 Nov; 29 (4):753-72
    View PubMed
  734. McDade EM, Boot BP, Christianson TJ, Pankratz VS, Boeve BF, Ferman TJ, Bieniek K, Hollman JH, Roberts RO, Mielke MM, Knopman DS, Petersen RC. Subtle gait changes in patients with REM sleep behavior disorder. Mov Disord. 2013 Nov; 28 (13):1847-53 Epub 2013 Oct 15
    View PubMed
  735. Hamedani AG, Rose KM, Peterlin BL, Mosley TH, Coker LH, Jack CR, Knopman DS, Alonso A, Gottesman RF. Migraine and white matter hyperintensities: the ARIC MRI study. Neurology. 2013 Oct 8; 81 (15):1308-13 Epub 2013 Aug 23
    View PubMed
  736. van Blitterswijk M, Baker MC, DeJesus-Hernandez M, Ghidoni R, Benussi L, Finger E, Hsiung GY, Kelley BJ, Murray ME, Rutherford NJ, Brown PE, Ravenscroft T, Mullen B, Ash PE, Bieniek KF, Hatanpaa KJ, Karydas A, Wood EM, Coppola G, Bigio EH, Lippa C, Strong MJ, Beach TG, Knopman DS, Huey ED, Mesulam M, Bird T, White CL 3rd, Kertesz A, Geschwind DH, Van Deerlin VM, Petersen RC, Binetti G, Miller BL, Petrucelli L, Wszolek ZK, Boylan KB, Graff-Radford NR, Mackenzie IR, Boeve BF, Dickson DW, Rademakers R. C9ORF72 repeat expansions in cases with previously identified pathogenic mutations. Neurology. 2013 Oct 8; 81 (15):1332-41 Epub 2013 Sept 11
    View PubMed
  737. van Blitterswijk M, DeJesus-Hernandez M, Niemantsverdriet E, Murray ME, Heckman MG, Diehl NN, Brown PH, Baker MC, Finch NA, Bauer PO, Serrano G, Beach TG, Josephs KA, Knopman DS, Petersen RC, Boeve BF, Graff-Radford NR, Boylan KB, Petrucelli L, Dickson DW, Rademakers R. Association between repeat sizes and clinical and pathological characteristics in carriers of C9ORF72 repeat expansions (Xpansize-72): a cross-sectional cohort study. Lancet Neurol. 2013 Oct; 12 (10):978-88 Epub 2013 Sept 05
    View PubMed
  738. Gill DP, Hubbard RA, Koepsell TD, Borrie MJ, Petrella RJ, Knopman DS, Kukull WA. Differences in rate of functional decline across three dementia types. Alzheimers Dement. 2013 Oct; 9(5 Suppl):S63-71. Epub 2013 May 02.
    View PubMed
  739. van Blitterswijk M, Baker MC, Bieniek KF, Knopman DS, Josephs KA, Boeve B, Caselli R, Wszolek ZK, Petersen R, Graff-Radford NR, Boylan KB, Dickson DW, Rademakers R. Profilin-1 mutations are rare in patients with amyotrophic lateral sclerosis and frontotemporal dementia. Amyotroph Lateral Scler Frontotemporal Degener. 2013 Sep; 14 (5-6):463-9 Epub 2013 May 02
    View PubMed
  740. Carrillo MC, Dean RA, Nicolas F, Miller DS, Berman R, Khachaturian Z, Bain LJ, Schindler R, Knopman D. Revisiting the framework of the National Institute on Aging-Alzheimer's Association diagnostic criteria. Alzheimers Dement. 2013 Sep; 9(5):594-601.
    View PubMed
  741. Boot BP, Orr CF, Ahlskog JE, Ferman TJ, Roberts R, Pankratz VS, Dickson DW, Parisi J, Aakre JA, Geda YE, Knopman DS, Petersen RC, Boeve BF. Risk factors for dementia with Lewy bodies: a case-control study. Neurology. 2013 Aug 27; 81 (9):833-40 Epub 2013 July 26
    View PubMed
  742. Mielke MM, Roberts RO, Savica R, Cha R, Drubach DI, Christianson T, Pankratz VS, Geda YE, Machulda MM, Ivnik RJ, Knopman DS, Boeve BF, Rocca WA, Petersen RC. Assessing the temporal relationship between cognition and gait: slow gait predicts cognitive decline in the Mayo Clinic Study of Aging. J Gerontol A Biol Sci Med Sci. 2013 Aug; 68 (8):929-37 Epub 2012 Dec 18
    View PubMed
  743. Petersen RC, Aisen P, Boeve BF, Geda YE, Ivnik RJ, Knopman DS, Mielke M, Pankratz VS, Roberts R, Rocca WA, Weigand S, Weiner M, Wiste H, Jack CR Jr. Mild cognitive impairment due to Alzheimer disease in the community. Ann Neurol. 2013 Aug; 74 (2):199-208
    View PubMed
  744. Wicklund MR, Knopman DS. Brain MRI findings in Wernicke encephalopathy. Neurol Clin Pract. 2013 Aug; 3 (4):363-364
    View PubMed
  745. Knopman DS, Jack CR Jr, Wiste HJ, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Roberts RO, Boeve BF, Petersen RC. Selective worsening of brain injury biomarker abnormalities in cognitively normal elderly persons with beta-amyloidosis. JAMA Neurol. 2013 Aug; 70 (8):1030-8
    View PubMed
  746. Kantarci K, Weigand SD, Przybelski SA, Preboske GM, Pankratz VS, Vemuri P, Senjem ML, Murphy MC, Gunter JL, Machulda MM, Ivnik RJ, Roberts RO, Boeve BF, Rocca WA, Knopman DS, Petersen RC, Jack CR Jr. MRI and MRS predictors of mild cognitive impairment in a population-based sample. Neurology. 2013 Jul 9; 81 (2):126-33 Epub 2013 June 12
    View PubMed
  747. Fugate JE, Moore SA, Knopman DS, Claassen DO, Wijdicks EF, White RD, Rabinstein AA. Cognitive outcomes of patients undergoing therapeutic hypothermia after cardiac arrest. Neurology. 2013 Jul 2; 81 (1):40-5 Epub 2013 May 17
    View PubMed
  748. Graff-Radford J, Rubin MN, Jones DT, Aksamit AJ, Ahlskog JE, Knopman DS, Petersen RC, Boeve BF, Josephs KA. The alien limb phenomenon. J Neurol. 2013 Jul; 260 (7):1880-8 Epub 2013 Apr 10
    View PubMed
  749. Rayaprolu S, Mullen B, Baker M, Lynch T, Finger E, Seeley WW, Hatanpaa KJ, Lomen-Hoerth C, Kertesz A, Bigio EH, Lippa C, Josephs KA, Knopman DS, White CL 3rd, Caselli R, Mackenzie IR, Miller BL, Boczarska-Jedynak M, Opala G, Krygowska-Wajs A, Barcikowska M, Younkin SG, Petersen RC, Ertekin-Taner N, Uitti RJ, Meschia JF, Boylan KB, Boeve BF, Graff-Radford NR, Wszolek ZK, Dickson DW, Rademakers R, Ross OA. TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease. Mol Neurodegener. 2013 Jun 21; 8:19 Epub 2013 June 21
    View PubMed
  750. Lowe VJ, Peller PJ, Weigand SD, Montoya Quintero C, Tosakulwong N, Vemuri P, Senjem ML, Jordan L, Jack CR Jr, Knopman D, Petersen RC. Application of the National Institute on Aging-Alzheimer's Association AD criteria to ADNI. Neurology. 2013 Jun 4; 80 (23):2130-7 Epub 2013 May 03
    View PubMed
  751. Sprung J, Jankowski CJ, Roberts RO, Weingarten TN, Aguilar AL, Runkle KJ, Tucker AK, McLaren KC, Schroeder DR, Hanson AC, Knopman DS, Gurrieri C, Warner DO. Anesthesia and incident dementia: a population-based, nested, case-control study. Mayo Clin Proc. 2013 Jun; 88 (6):552-61 Epub 2013 May 01
    View PubMed
  752. Boeve BF, Molano JR, Ferman TJ, Lin SC, Bieniek K, Tippmann-Peikert M, Boot B, St Louis EK, Knopman DS, Petersen RC, Silber MH. Validation of the Mayo Sleep Questionnaire to screen for REM sleep behavior disorder in a community-based sample. J Clin Sleep Med. 2013 May 15; 9 (5):475-80
    View PubMed
  753. Graff-Radford NR, Knopman DS, Penman AD, Coker LH, Mosley TH. Do systolic BP and pulse pressure relate to ventricular enlargement? Eur J Neurol. 2013 Apr; 20 (4):720-4 Epub 2013 Jan 07
    View PubMed
  754. Knopman DS, Jack CR Jr, Wiste HJ, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Roberts RO, Boeve BF, Petersen RC. Brain injury biomarkers are not dependent on beta-amyloid in normal elderly. Ann Neurol. 2013 Apr; 73 (4):472-80 Epub 2013 Feb 19
    View PubMed
  755. De Vries R, Ryan KA, Stanczyk A, Appelbaum PS, Damschroder L, Knopman DS, Kim SY. Public's approach to surrogate consent for dementia research: cautious pragmatism. Am J Geriatr Psychiatry. 2013 Apr; 21(4):364-72. Epub 2013 Jan 12.
    View PubMed
  756. Nicholson AM, Baker MC, Finch NA, Rutherford NJ, Wider C, Graff-Radford NR, Nelson PT, Clark HB, Wszolek ZK, Dickson DW, Knopman DS, Rademakers R. CSF1R mutations link POLD and HDLS as a single disease entity. Neurology. 2013 Mar 12; 80 (11):1033-40 Epub 2013 Feb 13
    View PubMed
  757. Jack CR Jr, Wiste HJ, Lesnick TG, Weigand SD, Knopman DS, Vemuri P, Pankratz VS, Senjem ML, Gunter JL, Mielke MM, Lowe VJ, Boeve BF, Petersen RC. Brain beta-amyloid load approaches a plateau. Neurology. 2013 Mar 5; 80 (10):890-6 Epub 2013 Feb 27
    View PubMed
  758. Coon EA, Daube JR, Dejesus-Hernandez M, Adeli A, Savica R, Parisi JE, Dickson DW, Josephs KA, Baker MC, Johnson KA, Ivnik RJ, Petersen RC, Knopman DS, Boylan KB, Rademakers R, Boeve BF. Clinical and electrophysiologic variability in amyotrophic lateral sclerosis within a kindred harboring the C9ORF72 repeat expansion. Amyotroph Lateral Scler Frontotemporal Degener. 2013 Mar; 14 (2):132-7 Epub 2012 Oct 04
    View PubMed
  759. Roberts RO, Geda YE, Knopman DS, Cha RH, Pankratz VS, Boeve BF, Tangalos EG, Ivnik RJ, Mielke MM, Petersen RC. Cardiac disease associated with increased risk of nonamnestic cognitive impairment: stronger effect on women. JAMA Neurol. 2013 Mar 1; 70 (3):374-82
    View PubMed
  760. Boxer AL, Gold M, Huey E, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, Mackenzie IR, Mitic L, Roberson ED, Van Kammen D, Cantillon M, Zahs K, Salloway S, Morris J, Tong G, Feldman H, Fillit H, Dickinson S, Khachaturian Z, Sutherland M, Farese R, Miller BL, Cummings J. Frontotemporal degeneration, the next therapeutic frontier: molecules and animal models for frontotemporal degeneration drug development. Alzheimers Dement. 2013 Mar; 9(2):176-88. Epub 2012 Oct 05.
    View PubMed
  761. Boxer AL, Gold M, Huey E, Hu WT, Rosen H, Kramer J, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, Mackenzie IR, Mitic L, Roberson ED, Van Kammen D, Cantillon M, Zahs K, Jackson G, Salloway S, Morris J, Tong G, Feldman H, Fillit H, Dickinson S, Khachaturian ZS, Sutherland M, Abushakra S, Lewcock J, Farese R, Kenet RO, Laferla F, Perrin S, Whitaker S, Honig L, Mesulam MM, Boeve B, Grossman M, Miller BL, Cummings JL. The advantages of frontotemporal degeneration drug development (part 2 of frontotemporal degeneration: the next therapeutic frontier). Alzheimers Dement. 2013 Mar; 9(2):189-98. Epub 2012 Oct 10.
    View PubMed
  762. Jack CR Jr, Knopman DS, Jagust WJ, Petersen RC, Weiner MW, Aisen PS, Shaw LM, Vemuri P, Wiste HJ, Weigand SD, Lesnick TG, Pankratz VS, Donohue MC, Trojanowski JQ. Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers. Lancet Neurol. 2013 Feb; 12 (2):207-16
    View PubMed
  763. Josephs KA, Whitwell JL, Murray ME, Parisi JE, Graff-Radford NR, Knopman DS, Boeve BF, Senjem ML, Rademakers R, Jack CR Jr, Petersen RC, Dickson DW. Corticospinal tract degeneration associated with TDP-43 type C pathology and semantic dementia. Brain. 2013 Feb; 136 (Pt 2):455-70 Epub 2013 Jan 28
    View PubMed
  764. Whitwell JL, Xu J, Mandrekar J, Boeve BF, Knopman DS, Parisi JE, Senjem ML, Dickson DW, Petersen RC, Rademakers R, Jack CR Jr, Josephs KA. Frontal asymmetry in behavioral variant frontotemporal dementia: clinicoimaging and pathogenetic correlates. Neurobiol Aging. 2013 Feb; 34 (2):636-9 Epub 2012 Apr 11
    View PubMed
  765. Boxer AL, Knopman DS, Kaufer DI, Grossman M, Onyike C, Graf-Radford N, Mendez M, Kerwin D, Lerner A, Wu CK, Koestler M, Shapira J, Sullivan K, Klepac K, Lipowski K, Ullah J, Fields S, Kramer JH, Merrilees J, Neuhaus J, Mesulam MM, Miller BL. Memantine in patients with frontotemporal lobar degeneration: a multicentre, randomised, double-blind, placebo-controlled trial. Lancet Neurol. 2013 Feb; 12(2):149-56. Epub 2013 Jan 02.
    View PubMed
  766. Graff-Radford J, Boeve BF, Drubach DA, Knopman DS, Ahlskog JE, Golden EC, Drubach DI, Petersen RC, Josephs KA. Limb immobilization and corticobasal syndrome. Parkinsonism Relat Disord. 2012 Dec; 18 (10):1097-9 Epub 2012 June 20
    View PubMed
  767. Rutherford NJ, Heckman MG, Dejesus-Hernandez M, Baker MC, Soto-Ortolaza AI, Rayaprolu S, Stewart H, Finger E, Volkening K, Seeley WW, Hatanpaa KJ, Lomen-Hoerth C, Kertesz A, Bigio EH, Lippa C, Knopman DS, Kretzschmar HA, Neumann M, Caselli RJ, White CL 3rd, Mackenzie IR, Petersen RC, Strong MJ, Miller BL, Boeve BF, Uitti RJ, Boylan KB, Wszolek ZK, Graff-Radford NR, Dickson DW, Ross OA, Rademakers R. Length of normal alleles of C9ORF72 GGGGCC repeat do not influence disease phenotype. Neurobiol Aging. 2012 Dec; 33(12):2950.e5-7. Epub 2012 Jul 26.
    View PubMed
  768. Knopman DS. Donepezil 23 mg: An empty suit. Neurol Clin Pract. 2012 Dec; 2 (4):352-355
    View PubMed
  769. Vemuri P, Lesnick TG, Przybelski SA, Knopman DS, Roberts RO, Lowe VJ, Kantarci K, Senjem ML, Gunter JL, Boeve BF, Petersen RC, Jack CR Jr. Effect of lifestyle activities on Alzheimer disease biomarkers and cognition. Ann Neurol. 2012 Nov; 72 (5):730-8
    View PubMed
  770. Mielke MM, Wiste HJ, Weigand SD, Knopman DS, Lowe VJ, Roberts RO, Geda YE, Swenson-Dravis DM, Boeve BF, Senjem ML, Vemuri P, Petersen RC, Jack CR Jr. Indicators of amyloid burden in a population-based study of cognitively normal elderly. Neurology. 2012 Oct 9; 79 (15):1570-7 Epub 2012 Sept 12
    View PubMed
  771. Whitwell JL, Dickson DW, Murray ME, Weigand SD, Tosakulwong N, Senjem ML, Knopman DS, Boeve BF, Parisi JE, Petersen RC, Jack CR Jr, Josephs KA. Neuroimaging correlates of pathologically defined subtypes of Alzheimer's disease: a case-control study. Lancet Neurol. 2012 Oct; 11 (10):868-77 Epub 2012 Sept 03
    View PubMed
  772. Savica R, Adeli A, Vemuri P, Knopman DS, Dejesus-Hernandez M, Rademakers R, Fields JA, Whitwell J, Jack CR, Lowe V, Petersen RC, Boeve BF. Characterization of a family with c9FTD/ALS associated with the GGGGCC repeat expansion in C9ORF72. Arch Neurol. 2012 Sep; 69 (9):1164-9
    View PubMed
  773. Kantarci K, Lowe VJ, Boeve BF, Weigand SD, Senjem ML, Przybelski SA, Dickson DW, Parisi JE, Knopman DS, Smith GE, Ferman TJ, Petersen RC, Jack CR Jr. Multimodality imaging characteristics of dementia with Lewy bodies. Neurobiol Aging. 2012 Sep; 33 (9):2091-105 Epub 2011 Oct 21
    View PubMed
  774. Kantarci K, Ferman TJ, Boeve BF, Weigand SD, Przybelski S, Vemuri P, Murray ME, Senjem ML, Smith GE, Knopman DS, Petersen RC, Jack CR Jr, Parisi JE, Dickson DW. Focal atrophy on MRI and neuropathologic classification of dementia with Lewy bodies. Neurology. 2012 Aug 7; 79 (6):553-60 Epub 2012 July 25
    View PubMed
  775. Graff-Radford J, Boeve BF, Pedraza O, Ferman TJ, Przybelski S, Lesnick TG, Vemuri P, Senjem ML, Smith GE, Knopman DS, Lowe V, Jack CR Jr, Petersen RC, Kantarci K. Imaging and acetylcholinesterase inhibitor response in dementia with Lewy bodies. Brain. 2012 Aug; 135 (Pt 8):2470-7 Epub 2012 July 18
    View PubMed
  776. Jack CR Jr, Vemuri P, Wiste HJ, Weigand SD, Lesnick TG, Lowe V, Kantarci K, Bernstein MA, Senjem ML, Gunter JL, Boeve BF, Trojanowski JQ, Shaw LM, Aisen PS, Weiner MW, Petersen RC, Knopman DS, Alzheimer's Disease Neuroimaging Initiative. Shapes of the trajectories of 5 major biomarkers of Alzheimer disease. Arch Neurol. 2012 Jul; 69 (7):856-67
    View PubMed
  777. Jack CR Jr, Knopman DS, Weigand SD, Wiste HJ, Vemuri P, Lowe V, Kantarci K, Gunter JL, Senjem ML, Ivnik RJ, Roberts RO, Rocca WA, Boeve BF, Petersen RC. An operational approach to National Institute on Aging-Alzheimer's Association criteria for preclinical Alzheimer disease. Ann Neurol. 2012 Jun; 71 (6):765-75 Epub 2012 Apr 09
    View PubMed
  778. Knopman DS. Diagnostic tests for Alzheimer disease: FDG-PET imaging is a player in search of a role. Neurol Clin Pract. 2012 Jun; 2 (2):151-153
    View PubMed
  779. Perry DC, Whitwell JL, Boeve BF, Pankratz VS, Knopman DS, Petersen RC, Jack CR Jr, Josephs KA. Voxel-based morphometry in patients with obsessive-compulsive behaviors in behavioral variant frontotemporal dementia. Eur J Neurol. 2012 Jun; 19 (6):911-7 Epub 2012 Jan 28
    View PubMed
  780. Knopman DS, Jack CR Jr, Wiste HJ, Weigand SD, Vemuri P, Lowe V, Kantarci K, Gunter JL, Senjem ML, Ivnik RJ, Roberts RO, Boeve BF, Petersen RC. Short-term clinical outcomes for stages of NIA-AA preclinical Alzheimer disease. Neurology. 2012 May 15; 78 (20):1576-82 Epub 2012 May 02
    View PubMed
  781. Bis JC, DeCarli C, Smith AV, van der Lijn F, Crivello F, Fornage M, Debette S, Shulman JM, Schmidt H, Srikanth V, Schuur M, Yu L, Choi SH, Sigurdsson S, Verhaaren BF, DeStefano AL, Lambert JC, Jack CR Jr, Struchalin M, Stankovich J, Ibrahim-Verbaas CA, Fleischman D, Zijdenbos A, den Heijer T, Mazoyer B, Coker LH, Enzinger C, Danoy P, Amin N, Arfanakis K, van Buchem MA, de Bruijn RF, Beiser A, Dufouil C, Huang J, Cavalieri M, Thomson R, Niessen WJ, Chibnik LB, Gislason GK, Hofman A, Pikula A, Amouyel P, Freeman KB, Phan TG, Oostra BA, Stein JL, Medland SE, Vasquez AA, Hibar DP, Wright MJ, Franke B, Martin NG, Thompson PM, Enhancing Neuro Imaging Genetics through Meta-Analysis Consortium, Nalls MA, Uitterlinden AG, Au R, Elbaz A, Beare RJ, van Swieten JC, Lopez OL, Harris TB, Chouraki V, Breteler MM, De Jager PL, Becker JT, Vernooij MW, Knopman D, Fazekas F, Wolf PA, van der Lugt A, Gudnason V, Longstreth WT Jr, Brown MA, Bennett DA, van Duijn CM, Mosley TH, Schmidt R, Tzourio C, Launer LJ, Ikram MA, Seshadri S, Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nat Genet. 2012 May; 44(5):545-51. Epub 2012 Apr 15.
    View PubMed
  782. Geda YE, Silber TC, Roberts RO, Knopman DS, Christianson TJ, Pankratz VS, Boeve BF, Tangalos EG, Petersen RC. Computer activities, physical exercise, aging, and mild cognitive impairment: a population-based study. Mayo Clin Proc. 2012 May; 87 (5):437-42
    View PubMed
  783. Whitwell JL, Wiste HJ, Weigand SD, Rocca WA, Knopman DS, Roberts RO, Boeve BF, Petersen RC, Jack CR Jr, Alzheimer Disease Neuroimaging Initiative. Comparison of imaging biomarkers in the Alzheimer Disease Neuroimaging Initiative and the Mayo Clinic Study of Aging. Arch Neurol. 2012 May; 69 (5):614-22
    View PubMed
  784. Ikram MA, Fornage M, Smith AV, Seshadri S, Schmidt R, Debette S, Vrooman HA, Sigurdsson S, Ropele S, Taal HR, Mook-Kanamori DO, Coker LH, Longstreth WT Jr, Niessen WJ, DeStefano AL, Beiser A, Zijdenbos AP, Struchalin M, Jack CR Jr, Rivadeneira F, Uitterlinden AG, Knopman DS, Hartikainen AL, Pennell CE, Thiering E, Steegers EA, Hakonarson H, Heinrich J, Palmer LJ, Jarvelin MR, McCarthy MI, Grant SF, St Pourcain B, Timpson NJ, Smith GD, Sovio U, Early Growth Genetics Consortium, Nalls MA, Au R, Hofman A, Gudnason H, van der Lugt A, Harris TB, Meeks WM, Vernooij MW, van Buchem MA, Catellier D, Jaddoe VW, Gudnason V, Windham BG, Wolf PA, van Duijn CM, Mosley TH Jr, Schmidt H, Launer LJ, Breteler MM, DeCarli C, Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. Common variants at 6q22 and 17q21 are associated with intracranial volume. Nat Genet. 2012 May; 44(5):539-44. Epub 2012 Apr 15.
    View PubMed
  785. McDade E, Boeve BF, Burrus TM, Boot BP, Kantarci K, Fields J, Lowe VJ, Peller P, Knopman D, Baker M, Finch N, Rademakers R, Petersen R. Similar clinical and neuroimaging features in monozygotic twin pair with mutation in progranulin. Neurology. 2012 Apr 17; 78 (16):1245-9 Epub 2012 Apr 04
    View PubMed
  786. Whitwell JL, Weigand SD, Boeve BF, Senjem ML, Gunter JL, DeJesus-Hernandez M, Rutherford NJ, Baker M, Knopman DS, Wszolek ZK, Parisi JE, Dickson DW, Petersen RC, Rademakers R, Jack CR Jr, Josephs KA. Neuroimaging signatures of frontotemporal dementia genetics: C9ORF72, tau, progranulin and sporadics. Brain. 2012 Mar; 135 (Pt 3):794-806
    View PubMed
  787. Boeve BF, Boylan KB, Graff-Radford NR, DeJesus-Hernandez M, Knopman DS, Pedraza O, Vemuri P, Jones D, Lowe V, Murray ME, Dickson DW, Josephs KA, Rush BK, Machulda MM, Fields JA, Ferman TJ, Baker M, Rutherford NJ, Adamson J, Wszolek ZK, Adeli A, Savica R, Boot B, Kuntz KM, Gavrilova R, Reeves A, Whitwell J, Kantarci K, Jack CR Jr, Parisi JE, Lucas JA, Petersen RC, Rademakers R. Characterization of frontotemporal dementia and/or amyotrophic lateral sclerosis associated with the GGGGCC repeat expansion in C9ORF72. Brain. 2012 Mar; 135 (Pt 3):765-83
    View PubMed
  788. Roberts RO, Geda YE, Knopman DS, Cha RH, Pankratz VS, Boeve BF, Tangalos EG, Ivnik RJ, Rocca WA, Petersen RC. The incidence of MCI differs by subtype and is higher in men: the Mayo Clinic Study of Aging. Neurology. 2012 Jan 31; 78 (5):342-51 Epub 2012 Jan 25
    View PubMed
  789. Kantarci K, Lowe V, Przybelski SA, Weigand SD, Senjem ML, Ivnik RJ, Preboske GM, Roberts R, Geda YE, Boeve BF, Knopman DS, Petersen RC, Jack CR Jr. APOE modifies the association between Abeta load and cognition in cognitively normal older adults. Neurology. 2012 Jan 24; 78 (4):232-40 Epub 2011 Dec 21
    View PubMed
  790. Rademakers R, Baker M, Nicholson AM, Rutherford NJ, Finch N, Soto-Ortolaza A, Lash J, Wider C, Wojtas A, DeJesus-Hernandez M, Adamson J, Kouri N, Sundal C, Shuster EA, Aasly J, MacKenzie J, Roeber S, Kretzschmar HA, Boeve BF, Knopman DS, Petersen RC, Cairns NJ, Ghetti B, Spina S, Garbern J, Tselis AC, Uitti R, Das P, Van Gerpen JA, Meschia JF, Levy S, Broderick DF, Graff-Radford N, Ross OA, Miller BB, Swerdlow RH, Dickson DW, Wszolek ZK. Mutations in the colony stimulating factor 1 receptor (CSF1R) gene cause hereditary diffuse leukoencephalopathy with spheroids. Nat Genet. 2011 Dec 25; 44(2):200-5.
    View PubMed
  791. Kim SY, Kim HM, Knopman DS, De Vries R, Damschroder L, Appelbaum PS. Effect of public deliberation on attitudes toward surrogate consent for dementia research. Neurology. 2011 Dec 13; 77(24):2097-104. Epub 2011 Oct 05.
    View PubMed
  792. Marin-Padilla M, Knopman DS. Developmental aspects of the intracerebral microvasculature and perivascular spaces: insights into brain response to late-life diseases. J Neuropathol Exp Neurol. 2011 Dec; 70(12):1060-9.
    View PubMed
  793. Jack CR Jr, Vemuri P, Wiste HJ, Weigand SD, Aisen PS, Trojanowski JQ, Shaw LM, Bernstein MA, Petersen RC, Weiner MW, Knopman DS, Alzheimer's Disease Neuroimaging Initiative. Evidence for ordering of Alzheimer disease biomarkers. Arch Neurol. 2011 Dec; 68 (12):1526-35 Epub 2011 Aug 08
    View PubMed
  794. Whitwell JL, Jack CR Jr, Parisi JE, Knopman DS, Boeve BF, Petersen RC, Dickson DW, Josephs KA. Imaging signatures of molecular pathology in behavioral variant frontotemporal dementia. J Mol Neurosci. 2011 Nov; 45 (3):372-8 Epub 2011 May 10
    View PubMed
  795. Knopman DS, Roberts RO. Estimating the number of persons with frontotemporal lobar degeneration in the US population. J Mol Neurosci. 2011 Nov; 45 (3):330-5 Epub 2011 May 17
    View PubMed
  796. DeJesus-Hernandez M, Mackenzie IR, Boeve BF, Boxer AL, Baker M, Rutherford NJ, Nicholson AM, Finch NA, Flynn H, Adamson J, Kouri N, Wojtas A, Sengdy P, Hsiung GY, Karydas A, Seeley WW, Josephs KA, Coppola G, Geschwind DH, Wszolek ZK, Feldman H, Knopman DS, Petersen RC, Miller BL, Dickson DW, Boylan KB, Graff-Radford NR, Rademakers R. Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. Neuron. 2011 Oct 20; 72 (2):245-56 Epub 2011 Sept 21
    View PubMed
  797. Jones DT, Machulda MM, Vemuri P, McDade EM, Zeng G, Senjem ML, Gunter JL, Przybelski SA, Avula RT, Knopman DS, Boeve BF, Petersen RC, Jack CR Jr. Age-related changes in the default mode network are more advanced in Alzheimer disease. Neurology. 2011 Oct 18; 77 (16):1524-31 Epub 2011 Oct 05
    View PubMed
  798. Pakhomov SV, Kaiser EA, Boley DL, Marino SE, Knopman DS, Birnbaum AK. Effects of age and dementia on temporal cycles in spontaneous speech fluency. J Neurolinguistics. 2011 Oct; 24(6):619-35.
    View PubMed
  799. Kantarci K, Lowe V, Przybelski SA, Senjem ML, Weigand SD, Ivnik RJ, Roberts R, Geda YE, Boeve BF, Knopman DS, Petersen RC, Jack CR Jr. Magnetic resonance spectroscopy, beta-amyloid load, and cognition in a population-based sample of cognitively normal older adults. Neurology. 2011 Sep 6; 77 (10):951-8 Epub 2011 Aug 24
    View PubMed
  800. Rascovsky K, Hodges JR, Knopman D, Mendez MF, Kramer JH, Neuhaus J, van Swieten JC, Seelaar H, Dopper EG, Onyike CU, Hillis AE, Josephs KA, Boeve BF, Kertesz A, Seeley WW, Rankin KP, Johnson JK, Gorno-Tempini ML, Rosen H, Prioleau-Latham CE, Lee A, Kipps CM, Lillo P, Piguet O, Rohrer JD, Rossor MN, Warren JD, Fox NC, Galasko D, Salmon DP, Black SE, Mesulam M, Weintraub S, Dickerson BC, Diehl-Schmid J, Pasquier F, Deramecourt V, Lebert F, Pijnenburg Y, Chow TW, Manes F, Grafman J, Cappa SF, Freedman M, Grossman M, Miller BL. Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Brain. 2011 Sep; 134(Pt 9):2456-77. Epub 2011 Aug 02.
    View PubMed
  801. Whitwell JL, Jack CR Jr, Przybelski SA, Parisi JE, Senjem ML, Boeve BF, Knopman DS, Petersen RC, Dickson DW, Josephs KA. Temporoparietal atrophy: a marker of AD pathology independent of clinical diagnosis. Neurobiol Aging. 2011 Sep; 32 (9):1531-41 Epub 2009 Nov 14
    View PubMed
  802. Machulda MM, Jones DT, Vemuri P, McDade E, Avula R, Przybelski S, Boeve BF, Knopman DS, Petersen RC, Jack CR Jr. Effect of APOE epsilon4 status on intrinsic network connectivity in cognitively normal elderly subjects. Arch Neurol. 2011 Sep; 68 (9):1131-6 Epub 2011 May 09
    View PubMed
  803. Whitwell JL, Josephs KA, Avula R, Tosakulwong N, Weigand SD, Senjem ML, Vemuri P, Jones DT, Gunter JL, Baker M, Wszolek ZK, Knopman DS, Rademakers R, Petersen RC, Boeve BF, Jack CR Jr. Altered functional connectivity in asymptomatic MAPT subjects: a comparison to bvFTD. Neurology. 2011 Aug 30; 77 (9):866-74 Epub 2011 Aug 17
    View PubMed
  804. Ferman TJ, Boeve BF, Smith GE, Lin SC, Silber MH, Pedraza O, Wszolek Z, Graff-Radford NR, Uitti R, Van Gerpen J, Pao W, Knopman D, Pankratz VS, Kantarci K, Boot B, Parisi JE, Dugger BN, Fujishiro H, Petersen RC, Dickson DW. Inclusion of RBD improves the diagnostic classification of dementia with Lewy bodies. Neurology. 2011 Aug 30; 77 (9):875-82 Epub 2011 Aug 17
    View PubMed
  805. Ross OA, Rutherford NJ, Baker M, Soto-Ortolaza AI, Carrasquillo MM, DeJesus-Hernandez M, Adamson J, Li M, Volkening K, Finger E, Seeley WW, Hatanpaa KJ, Lomen-Hoerth C, Kertesz A, Bigio EH, Lippa C, Woodruff BK, Knopman DS, White CL 3rd, Van Gerpen JA, Meschia JF, Mackenzie IR, Boylan K, Boeve BF, Miller BL, Strong MJ, Uitti RJ, Younkin SG, Graff-Radford NR, Petersen RC, Wszolek ZK, Dickson DW, Rademakers R. Ataxin-2 repeat-length variation and neurodegeneration. Hum Mol Genet. 2011 Aug 15; 20(16):3207-12. Epub 2011 May 24.
    View PubMed
  806. Whitwell JL, Weigand SD, Gunter JL, Boeve BF, Rademakers R, Baker M, Knopman DS, Wszolek ZK, Petersen RC, Jack CR Jr, Josephs KA. Trajectories of brain and hippocampal atrophy in FTD with mutations in MAPT or GRN. Neurology. 2011 Jul 26; 77 (4):393-8 Epub 2011 July 13
    View PubMed
  807. Kantarci K, Senjem ML, Avula R, Zhang B, Samikoglu AR, Weigand SD, Przybelski SA, Edmonson HA, Vemuri P, Knopman DS, Boeve BF, Ivnik RJ, Smith GE, Petersen RC, Jack CR Jr. Diffusion tensor imaging and cognitive function in older adults with no dementia. Neurology. 2011 Jul 5; 77 (1):26-34 Epub 2011 May 18
    View PubMed
  808. Pathan SS, Gottesman RF, Mosley TH, Knopman DS, Sharrett AR, Alonso A. Association of lung function with cognitive decline and dementia: the Atherosclerosis Risk in Communities (ARIC) Study. Eur J Neurol. 2011 Jun; 18(6):888-98. Epub 2011 Jan 18.
    View PubMed
  809. Fornage M, Debette S, Bis JC, Schmidt H, Ikram MA, Dufouil C, Sigurdsson S, Lumley T, DeStefano AL, Fazekas F, Vrooman HA, Shibata DK, Maillard P, Zijdenbos A, Smith AV, Gudnason H, de Boer R, Cushman M, Mazoyer B, Heiss G, Vernooij MW, Enzinger C, Glazer NL, Beiser A, Knopman DS, Cavalieri M, Niessen WJ, Harris TB, Petrovic K, Lopez OL, Au R, Lambert JC, Hofman A, Gottesman RF, Garcia M, Heckbert SR, Atwood LD, Catellier DJ, Uitterlinden AG, Yang Q, Smith NL, Aspelund T, Romero JR, Rice K, Taylor KD, Nalls MA, Rotter JI, Sharrett R, van Duijn CM, Amouyel P, Wolf PA, Gudnason V, van der Lugt A, Boerwinkle E, Psaty BM, Seshadri S, Tzourio C, Breteler MM, Mosley TH, Schmidt R, Longstreth WT, DeCarli C, Launer LJ. Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium. Ann Neurol. 2011 Jun; 69(6):928-39.
    View PubMed
  810. Negash S, Smith GE, Pankratz S, Aakre J, Geda YE, Roberts RO, Knopman DS, Boeve BF, Ivnik RJ, Petersen RC. Successful aging: definitions and prediction of longevity and conversion to mild cognitive impairment. Am J Geriatr Psychiatry. 2011 Jun; 19 (6):581-8
    View PubMed
  811. Coon EA, Sorenson EJ, Whitwell JL, Knopman DS, Josephs KA. Predicting survival in frontotemporal dementia with motor neuron disease. Neurology. 2011 May 31; 76 (22):1886-93
    View PubMed
  812. Knopman DS, Penman AD, Catellier DJ, Coker LH, Shibata DK, Sharrett AR, Mosley TH Jr. Vascular risk factors and longitudinal changes on brain MRI: the ARIC study. Neurology. 2011 May 31; 76 (22):1879-85 Epub 2011 May 04
    View PubMed
  813. McKhann GM, Knopman DS, Chertkow H, Hyman BT, Jack CR Jr, Kawas CH, Klunk WE, Koroshetz WJ, Manly JJ, Mayeux R, Mohs RC, Morris JC, Rossor MN, Scheltens P, Carrillo MC, Thies B, Weintraub S, Phelps CH. The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement. 2011 May; 7(3):263-9. Epub 2011 Apr 21.
    View PubMed
  814. Boeve BF, Molano JR, Ferman TJ, Smith GE, Lin SC, Bieniek K, Haidar W, Tippmann-Peikert M, Knopman DS, Graff-Radford NR, Lucas JA, Petersen RC, Silber MH. Validation of the Mayo Sleep Questionnaire to screen for REM sleep behavior disorder in an aging and dementia cohort. Sleep Med. 2011 May; 12 (5):445-53 Epub 2011 Feb 23
    View PubMed
  815. Vemuri P, Weigand SD, Przybelski SA, Knopman DS, Smith GE, Trojanowski JQ, Shaw LM, Decarli CS, Carmichael O, Bernstein MA, Aisen PS, Weiner M, Petersen RC, Jack CR Jr, Alzheimer's Disease Neuroimaging Initiative. Cognitive reserve and Alzheimer's disease biomarkers are independent determinants of cognition. Brain. 2011 May; 134 (Pt 5):1479-92 Epub 2011 Apr 07
    View PubMed
  816. Jack CR Jr, Albert MS, Knopman DS, McKhann GM, Sperling RA, Carrillo MC, Thies B, Phelps CH. Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement. 2011 May; 7 (3):257-62 Epub 2011 Apr 21
    View PubMed
  817. Knopman DS, Weintraub S, Pankratz VS. Language and behavior domains enhance the value of the clinical dementia rating scale. Alzheimers Dement. 2011 May; 7 (3):293-9
    View PubMed
  818. Gorno-Tempini ML, Hillis AE, Weintraub S, Kertesz A, Mendez M, Cappa SF, Ogar JM, Rohrer JD, Black S, Boeve BF, Manes F, Dronkers NF, Vandenberghe R, Rascovsky K, Patterson K, Miller BL, Knopman DS, Hodges JR, Mesulam MM, Grossman M. Classification of primary progressive aphasia and its variants. Neurology. 2011 Mar 15; 76(11):1006-14. Epub 2011 Feb 16.
    View PubMed
  819. Vemuri P, Simon G, Kantarci K, Whitwell JL, Senjem ML, Przybelski SA, Gunter JL, Josephs KA, Knopman DS, Boeve BF, Ferman TJ, Dickson DW, Parisi JE, Petersen RC, Jack CR Jr. Antemortem differential diagnosis of dementia pathology using structural MRI: Differential-STAND. Neuroimage. 2011 Mar 15; 55 (2):522-31 Epub 2010 Dec 31
    View PubMed
  820. Geda YE, Topazian HM, Roberts LA, Roberts RO, Knopman DS, Pankratz VS, Christianson TJ, Boeve BF, Tangalos EG, Ivnik RJ, Petersen RC. Engaging in cognitive activities, aging, and mild cognitive impairment: a population-based study. J Neuropsychiatry Clin Neurosci. 2011 Spring; 23 (2):149-54
    View PubMed
  821. Fatemi Y, Boeve BF, Duffy J, Petersen RC, Knopman DS, Cejka V, Smith GE, Geda YE. Neuropsychiatric aspects of primary progressive aphasia. J Neuropsychiatry Clin Neurosci. 2011 Spring; 23 (2):168-72
    View PubMed
  822. Weigand SD, Vemuri P, Wiste HJ, Senjem ML, Pankratz VS, Aisen PS, Weiner MW, Petersen RC, Shaw LM, Trojanowski JQ, Knopman DS, Jack CR Jr, Alzheimer's Disease Neuroimaging Initiative. Transforming cerebrospinal fluid Abeta42 measures into calculated Pittsburgh Compound B units of brain Abeta amyloid. Alzheimers Dement. 2011 Mar; 7 (2):133-41 Epub 2011 Feb 01
    View PubMed
  823. Josephs KA Jr, Whitwell JL, Weigand SD, Senjem ML, Boeve BF, Knopman DS, Smith GE, Ivnik RJ, Jack CR Jr, Petersen RC. Predicting functional decline in behavioural variant frontotemporal dementia. Brain. 2011 Feb; 134 (Pt 2):432-48 Epub 2011 Jan 20
    View PubMed
  824. Finch N, Carrasquillo MM, Baker M, Rutherford NJ, Coppola G, Dejesus-Hernandez M, Crook R, Hunter T, Ghidoni R, Benussi L, Crook J, Finger E, Hantanpaa KJ, Karydas AM, Sengdy P, Gonzalez J, Seeley WW, Johnson N, Beach TG, Mesulam M, Forloni G, Kertesz A, Knopman DS, Uitti R, White CL 3rd, Caselli R, Lippa C, Bigio EH, Wszolek ZK, Binetti G, Mackenzie IR, Miller BL, Boeve BF, Younkin SG, Dickson DW, Petersen RC, Graff-Radford NR, Geschwind DH, Rademakers R. TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers. Neurology. 2011 Feb 1; 76 (5):467-74 Epub 2010 Dec 22
    View PubMed
  825. Vemuri P, Weigand SD, Knopman DS, Kantarci K, Boeve BF, Petersen RC, Jack CR Jr. Time-to-event voxel-based techniques to assess regional atrophy associated with MCI risk of progression to AD. Neuroimage. 2011 Jan 15; 54 (2):985-91 Epub 2010 Sept 09
    View PubMed
  826. Whitwell JL, Jack CR Jr, Parisi JE, Senjem ML, Knopman DS, Boeve BF, Rademakers R, Baker M, Petersen RC, Dickson DW, Josephs KA. Does TDP-43 type confer a distinct pattern of atrophy in frontotemporal lobar degeneration? Neurology. 2010 Dec 14; 75 (24):2212-20
    View PubMed
  827. Whitwell JL, Jack CR Jr, Boeve BF, Parisi JE, Ahlskog JE, Drubach DA, Senjem ML, Knopman DS, Petersen RC, Dickson DW, Josephs KA. Imaging correlates of pathology in corticobasal syndrome. Neurology. 2010 Nov 23; 75 (21):1879-87
    View PubMed
  828. Jack CR Jr, Wiste HJ, Vemuri P, Weigand SD, Senjem ML, Zeng G, Bernstein MA, Gunter JL, Pankratz VS, Aisen PS, Weiner MW, Petersen RC, Shaw LM, Trojanowski JQ, Knopman DS, Alzheimer's Disease Neuroimaging Initiative. Brain beta-amyloid measures and magnetic resonance imaging atrophy both predict time-to-progression from mild cognitive impairment to Alzheimer's disease. Brain. 2010 Nov; 133 (11):3336-48 Epub 2010 Oct 08
    View PubMed
  829. Murray ME, Senjem ML, Petersen RC, Hollman JH, Preboske GM, Weigand SD, Knopman DS, Ferman TJ, Dickson DW, Jack CR Jr. Functional impact of white matter hyperintensities in cognitively normal elderly subjects. Arch Neurol. 2010 Nov; 67 (11):1379-85
    View PubMed
  830. Roberts RO, Knopman DS, Geda YE, Cha RH, Roger VL, Petersen RC. Coronary heart disease is associated with non-amnestic mild cognitive impairment. Neurobiol Aging. 2010 Nov; 31 (11):1894-902 Epub 2008 Dec 16
    View PubMed
  831. Fields JA, Machulda M, Aakre J, Ivnik RJ, Boeve BF, Knopman DS, Petersen RC, Smith GE. Utility of the DRS for predicting problems in day-to-day functioning. Clin Neuropsychol. 2010 Oct; 24(7):1167-80.
    View PubMed
  832. Teng E, Becker BW, Woo E, Knopman DS, Cummings JL, Lu PH. Utility of the functional activities questionnaire for distinguishing mild cognitive impairment from very mild Alzheimer disease. Alzheimer Dis Assoc Disord. 2010 Oct-Dec; 24 (4):348-53
    View PubMed
  833. Petersen RC, Roberts RO, Knopman DS, Geda YE, Cha RH, Pankratz VS, Boeve BF, Tangalos EG, Ivnik RJ, Rocca WA. Prevalence of mild cognitive impairment is higher in men. The Mayo Clinic Study of Aging. Neurology. 2010 Sep 7; 75 (10):889-97
    View PubMed
  834. Pakhomov SV, Smith GE, Chacon D, Feliciano Y, Graff-Radford N, Caselli R, Knopman DS. Computerized analysis of speech and language to identify psycholinguistic correlates of frontotemporal lobar degeneration. Cogn Behav Neurol. 2010 Sep; 23 (3):165-77
    View PubMed
  835. Kantarci K, Boeve BF, Wszolek ZK, Rademakers R, Whitwell JL, Baker MC, Senjem ML, Samikoglu AR, Knopman DS, Petersen RC, Jack CR Jr. MRS in presymptomatic MAPT mutation carriers: a potential biomarker for tau-mediated pathology. Neurology. 2010 Aug 31; 75 (9):771-8
    View PubMed
  836. Kantarci K, Senjem ML, Lowe VJ, Wiste HJ, Weigand SD, Kemp BJ, Frank AR, Shiung MM, Boeve BF, Knopman DS, Petersen RC, Jack CR Jr. Effects of age on the glucose metabolic changes in mild cognitive impairment. AJNR Am J Neuroradiol. 2010 Aug; 31 (7):1247-53 Epub 2010 Mar 18
    View PubMed
  837. Josephs KA, Whitwell JL, Boeve BF, Knopman DS, Petersen RC, Hu WT, Parisi JE, Dickson DW, Jack CR Jr. Anatomical differences between CBS-corticobasal degeneration and CBS-Alzheimer's disease. Mov Disord. 2010 Jul 15; 25 (9):1246-52
    View PubMed
  838. Vemuri P, Wiste HJ, Weigand SD, Knopman DS, Trojanowski JQ, Shaw LM, Bernstein MA, Aisen PS, Weiner M, Petersen RC, Jack CR Jr, Alzheimer's Disease Neuroimaging Initiative. Serial MRI and CSF biomarkers in normal aging, MCI, and AD. Neurology. 2010 Jul 13; 75 (2):143-51
    View PubMed
  839. Kim SY, Uhlmann RA, Appelbaum PS, Knopman DS, Kim HM, Damschroder L, Beattie E, Struble L, De Vries R. Deliberative assessment of surrogate consent in dementia research. Alzheimers Dement. 2010 Jul; 6(4):342-50. Epub 2010 Feb 26.
    View PubMed
  840. Cheung N, Mosley T, Islam A, Kawasaki R, Sharrett AR, Klein R, Coker LH, Knopman DS, Shibata DK, Catellier D, Wong TY. Retinal microvascular abnormalities and subclinical magnetic resonance imaging brain infarct: a prospective study. Brain. 2010 Jul; 133(Pt 7):1987-93. Epub 2010 Jun 02.
    View PubMed
  841. Kantarci K, Avula R, Senjem ML, Samikoglu AR, Zhang B, Weigand SD, Przybelski SA, Edmonson HA, Vemuri P, Knopman DS, Ferman TJ, Boeve BF, Petersen RC, Jack CR Jr. Dementia with Lewy bodies and Alzheimer disease: neurodegenerative patterns characterized by DTI. Neurology. 2010 Jun 1; 74 (22):1814-21
    View PubMed
  842. Whitwell JL, Avula R, Senjem ML, Kantarci K, Weigand SD, Samikoglu A, Edmonson HA, Vemuri P, Knopman DS, Boeve BF, Petersen RC, Josephs KA, Jack CR Jr. Gray and white matter water diffusion in the syndromic variants of frontotemporal dementia. Neurology. 2010 Apr 20; 74 (16):1279-87
    View PubMed
  843. Bei Hu Hu, Ross L, Neuhaus J, Knopman D, Kramer J, Boeve B, Caselli RJ, Graff-Radford N, Mendez MF, Miller BL, Boxer AL. Off-label medication use in frontotemporal dementia. Am J Alzheimers Dis Other Demen. 2010 Mar; 25 (2):128-33 Epub 2010 Feb 01
    View PubMed
  844. Pakhomov SV, Smith GE, Marino S, Birnbaum A, Graff-Radford N, Caselli R, Boeve B, Knopman DS. A computerized technique to assess language use patterns in patients with frontotemporal dementia. J Neurolinguistics. 2010 Mar 1; 23 (2):127-144
    View PubMed
  845. Vemuri P, Wiste HJ, Weigand SD, Knopman DS, Shaw LM, Trojanowski JQ, Aisen PS, Weiner M, Petersen RC, Jack CR Jr, Alzheimer's Disease Neuroimaging Initiative. Effect of apolipoprotein E on biomarkers of amyloid load and neuronal pathology in Alzheimer disease. Ann Neurol. 2010 Mar; 67 (3):308-16
    View PubMed
  846. Debette S, Bis JC, Fornage M, Schmidt H, Ikram MA, Sigurdsson S, Heiss G, Struchalin M, Smith AV, van der Lugt A, DeCarli C, Lumley T, Knopman DS, Enzinger C, Eiriksdottir G, Koudstaal PJ, DeStefano AL, Psaty BM, Dufouil C, Catellier DJ, Fazekas F, Aspelund T, Aulchenko YS, Beiser A, Rotter JI, Tzourio C, Shibata DK, Tscherner M, Harris TB, Rivadeneira F, Atwood LD, Rice K, Gottesman RF, van Buchem MA, Uitterlinden AG, Kelly-Hayes M, Cushman M, Zhu Y, Boerwinkle E, Gudnason V, Hofman A, Romero JR, Lopez O, van Duijn CM, Au R, Heckbert SR, Wolf PA, Mosley TH, Seshadri S, Breteler MM, Schmidt R, Launer LJ, Longstreth WT Jr. Genome-wide association studies of MRI-defined brain infarcts: meta-analysis from the CHARGE Consortium. Stroke. 2010 Feb; 41(2):210-7. Epub 2009 Dec 31.
    View PubMed
  847. Molano J, Boeve B, Ferman T, Smith G, Parisi J, Dickson D, Knopman D, Graff-Radford N, Geda Y, Lucas J, Kantarci K, Shiung M, Jack C, Silber M, Pankratz VS, Petersen R. Mild cognitive impairment associated with limbic and neocortical Lewy body disease: a clinicopathological study. Brain. 2010 Feb; 133 (Pt 2):540-56 Epub 2009 Nov 04
    View PubMed
  848. Kelley BJ, Haidar W, Boeve BF, Baker M, Shiung M, Knopman DS, Rademakers R, Hutton M, Adamson J, Kuntz KM, Dickson DW, Parisi JE, Smith GE, Petersen RC. Alzheimer disease-like phenotype associated with the c.154delA mutation in progranulin. Arch Neurol. 2010 Feb; 67 (2):171-7
    View PubMed
  849. Petersen RC, Roberts RO, Knopman DS, Boeve BF, Geda YE, Ivnik RJ, Smith GE, Jack CR Jr. Mild cognitive impairment: ten years later. Arch Neurol. 2009 Dec; 66 (12):1447-55
    View PubMed
  850. Josephs KA, Whitwell JL, Knopman DS, Boeve BF, Vemuri P, Senjem ML, Parisi JE, Ivnik RJ, Dickson DW, Petersen RC, Jack CR Jr. Two distinct subtypes of right temporal variant frontotemporal dementia. Neurology. 2009 Nov 3; 73 (18):1443-50
    View PubMed
  851. Hu WT, Seelaar H, Josephs KA, Knopman DS, Boeve BF, Sorenson EJ, McCluskey L, Elman L, Schelhaas HJ, Parisi JE, Kuesters B, Lee VM, Trojanowski JQ, Petersen RC, van Swieten JC, Grossman M. Survival profiles of patients with frontotemporal dementia and motor neuron disease. Arch Neurol. 2009 Nov; 66 (11):1359-64
    View PubMed
  852. Whitwell JL, Przybelski SA, Weigand SD, Ivnik RJ, Vemuri P, Gunter JL, Senjem ML, Shiung MM, Boeve BF, Knopman DS, Parisi JE, Dickson DW, Petersen RC, Jack CR Jr, Josephs KA. Distinct anatomical subtypes of the behavioural variant of frontotemporal dementia: a cluster analysis study. Brain. 2009 Nov; 132 (Pt 11):2932-46 Epub 2009 Sept 17
    View PubMed
  853. Whitwell JL, Jack CR Jr, Boeve BF, Senjem ML, Baker M, Ivnik RJ, Knopman DS, Wszolek ZK, Petersen RC, Rademakers R, Josephs KA. Atrophy patterns in IVS10+16, IVS10+3, N279K, S305N, P301L, and V337M MAPT mutations. Neurology. 2009 Sep 29; 73 (13):1058-65
    View PubMed
  854. Lesage SR, Mosley TH, Wong TY, Szklo M, Knopman D, Catellier DJ, Cole SR, Klein R, Coresh J, Coker LH, Sharrett AR. Retinal microvascular abnormalities and cognitive decline: the ARIC 14-year follow-up study. Neurology. 2009 Sep 15; 73(11):862-8.
    View PubMed
  855. Roberts RO, Geda YE, Knopman DS, Boeve BF, Christianson TJ, Pankratz VS, Kullo IJ, Tangalos EG, Ivnik RJ, Petersen RC. Association of C-reactive protein with mild cognitive impairment. Alzheimers Dement. 2009 Sep; 5 (5):398-405
    View PubMed
  856. Vemuri P, Wiste HJ, Weigand SD, Shaw LM, Trojanowski JQ, Weiner MW, Knopman DS, Petersen RC, Jack CR Jr, Alzheimer's Disease Neuroimaging Initiative. MRI and CSF biomarkers in normal, MCI, and AD subjects: predicting future clinical change. Neurology. 2009 Jul 28; 73 (4):294-301
    View PubMed
  857. Vemuri P, Wiste HJ, Weigand SD, Shaw LM, Trojanowski JQ, Weiner MW, Knopman DS, Petersen RC, Jack CR Jr, Alzheimer's Disease Neuroimaging Initiative. MRI and CSF biomarkers in normal, MCI, and AD subjects: diagnostic discrimination and cognitive correlations. Neurology. 2009 Jul 28; 73 (4):287-93
    View PubMed
  858. Hu WT, Rippon GW, Boeve BF, Knopman DS, Petersen RC, Parisi JE, Josephs KA. Alzheimer's disease and corticobasal degeneration presenting as corticobasal syndrome. Mov Disord. 2009 Jul 15; 24 (9):1375-9
    View PubMed
  859. Turner ST, Fornage M, Jack CR Jr, Mosley TH, Knopman DS, Kardia SL, Boerwinkle E, de Andrade M. Genomic susceptibility Loci for brain atrophy, ventricular volume, and leukoaraiosis in hypertensive sibships. Arch Neurol. 2009 Jul; 66 (7):847-57
    View PubMed
  860. Lowe VJ, Kemp BJ, Jack CR Jr, Senjem M, Weigand S, Shiung M, Smith G, Knopman D, Boeve B, Mullan B, Petersen RC. Comparison of 18F-FDG and PiB PET in cognitive impairment. J Nucl Med. 2009 Jun; 50 (6):878-86 Epub 2009 May 14
    View PubMed
  861. Knopman DS, Jack CR Jr, Kramer JH, Boeve BF, Caselli RJ, Graff-Radford NR, Mendez MF, Miller BL, Mercaldo ND. Brain and ventricular volumetric changes in frontotemporal lobar degeneration over 1 year. Neurology. 2009 May 26; 72 (21):1843-9
    View PubMed
  862. Kelley BJ, Haidar W, Boeve BF, Baker M, Graff-Radford NR, Krefft T, Frank AR, Jack CR Jr, Shiung M, Knopman DS, Josephs KA, Parashos SA, Rademakers R, Hutton M, Pickering-Brown S, Adamson J, Kuntz KM, Dickson DW, Parisi JE, Smith GE, Ivnik RJ, Petersen RC. Prominent phenotypic variability associated with mutations in Progranulin. Neurobiol Aging. 2009 May; 30 (5):739-51 Epub 2007 Oct 18
    View PubMed
  863. Knopman DS, Mosley TH, Catellier DJ, Coker LH, Atherosclerosis Risk in Communities Study Brain MRI Study. Fourteen-year longitudinal study of vascular risk factors, APOE genotype, and cognition: the ARIC MRI Study. Alzheimers Dement. 2009 May; 5 (3):207-14 Epub 2009 Apr 11
    View PubMed
  864. Machulda MM, Senjem ML, Weigand SD, Smith GE, Ivnik RJ, Boeve BF, Knopman DS, Petersen RC, Jack CR. Functional magnetic resonance imaging changes in amnestic and nonamnestic mild cognitive impairment during encoding and recognition tasks. J Int Neuropsychol Soc. 2009 May; 15 (3):372-82
    View PubMed
  865. Knopman DS, Roberts RO, Geda YE, Boeve BF, Pankratz VS, Cha RH, Tangalos EG, Ivnik RJ, Petersen RC. Association of prior stroke with cognitive function and cognitive impairment: a population-based study. Arch Neurol. 2009 May; 66 (5):614-9
    View PubMed
  866. Jack CR Jr, Lowe VJ, Weigand SD, Wiste HJ, Senjem ML, Knopman DS, Shiung MM, Gunter JL, Boeve BF, Kemp BJ, Weiner M, Petersen RC, Alzheimer's Disease Neuroimaging Initiative. Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: implications for sequence of pathological events in Alzheimer's disease. Brain. 2009 May; 132 (Pt 5):1355-65 Epub 2009 Mar 31
    View PubMed
  867. Kantarci K, Weigand SD, Przybelski SA, Shiung MM, Whitwell JL, Negash S, Knopman DS, Boeve BF, O'Brien PC, Petersen RC, Jack CR Jr. Risk of dementia in MCI: combined effect of cerebrovascular disease, volumetric MRI, and 1H MRS. Neurology. 2009 Apr 28; 72 (17):1519-25
    View PubMed
  868. Whitwell JL, Jack CR Jr, Boeve BF, Senjem ML, Baker M, Rademakers R, Ivnik RJ, Knopman DS, Wszolek ZK, Petersen RC, Josephs KA. Voxel-based morphometry patterns of atrophy in FTLD with mutations in MAPT or PGRN. Neurology. 2009 Mar 3; 72 (9):813-20
    View PubMed
  869. Rademakers R, Eriksen JL, Baker M, Robinson T, Ahmed Z, Lincoln SJ, Finch N, Rutherford NJ, Crook RJ, Josephs KA, Boeve BF, Knopman DS, Petersen RC, Parisi JE, Caselli RJ, Wszolek ZK, Uitti RJ, Feldman H, Hutton ML, Mackenzie IR, Graff-Radford NR, Dickson DW. Common variation in the miR-659 binding-site of GRN is a major risk factor for TDP43-positive frontotemporal dementia. Hum Mol Genet. 2008 Dec 1; 17 (23):3631-42 Epub 2008 Aug 21
    View PubMed
  870. Kantarci K, Petersen RC, Przybelski SA, Weigand SD, Shiung MM, Whitwell JL, Negash S, Ivnik RJ, Boeve BF, Knopman DS, Smith GE, Jack CR Jr. Hippocampal volumes, proton magnetic resonance spectroscopy metabolites, and cerebrovascular disease in mild cognitive impairment subtypes. Arch Neurol. 2008 Dec; 65 (12):1621-8
    View PubMed
  871. Knopman DS. Clinical trial design issues in mild to moderate Alzheimer disease. Cogn Behav Neurol. 2008 Dec; 21 (4):197-201
    View PubMed
  872. Josephs KA, Whitwell JL, Vemuri P, Senjem ML, Boeve BF, Knopman DS, Smith GE, Ivnik RJ, Petersen RC, Jack CR Jr. The anatomic correlate of prosopagnosia in semantic dementia. Neurology. 2008 Nov 11; 71 (20):1628-33
    View PubMed
  873. Knopman DS, Kramer JH, Boeve BF, Caselli RJ, Graff-Radford NR, Mendez MF, Miller BL, Mercaldo N. Development of methodology for conducting clinical trials in frontotemporal lobar degeneration. Brain. 2008 Nov; 131 (Pt 11):2957-68 Epub 2008 Oct 01
    View PubMed
  874. Jicha GA, Parisi JE, Dickson DW, Cha RH, Johnson KA, Smith GE, Boeve BF, Petersen RC, Knopman DS. Age and apoE associations with complex pathologic features in Alzheimer's disease. J Neurol Sci. 2008 Oct 15; 273 (1-2):34-9 Epub 2008 July 23
    View PubMed
  875. Geda YE, Roberts RO, Knopman DS, Petersen RC, Christianson TJ, Pankratz VS, Smith GE, Boeve BF, Ivnik RJ, Tangalos EG, Rocca WA. Prevalence of neuropsychiatric symptoms in mild cognitive impairment and normal cognitive aging: population-based study. Arch Gen Psychiatry. 2008 Oct; 65 (10):1193-8
    View PubMed
  876. Rutherford NJ, Zhang YJ, Baker M, Gass JM, Finch NA, Xu YF, Stewart H, Kelley BJ, Kuntz K, Crook RJ, Sreedharan J, Vance C, Sorenson E, Lippa C, Bigio EH, Geschwind DH, Knopman DS, Mitsumoto H, Petersen RC, Cashman NR, Hutton M, Shaw CE, Boylan KB, Boeve B, Graff-Radford NR, Wszolek ZK, Caselli RJ, Dickson DW, Mackenzie IR, Petrucelli L, Rademakers R. Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis. PLoS Genet. 2008 Sep 19; 4 (9):e1000193 Epub 2008 Sept 19
    View PubMed
  877. Whitwell JL, Josephs KA, Murray ME, Kantarci K, Przybelski SA, Weigand SD, Vemuri P, Senjem ML, Parisi JE, Knopman DS, Boeve BF, Petersen RC, Dickson DW, Jack CR Jr. MRI correlates of neurofibrillary tangle pathology at autopsy: a voxel-based morphometry study. Neurology. 2008 Sep 2; 71 (10):743-9
    View PubMed
  878. Knopman DS. Go to the head of the class to avoid vascular dementia and skip diabetes and obesity. Neurology. 2008 Sep; 71(14):1046-7.
  879. Kelley BJ, Knopman DS. Alternative medicine and Alzheimer disease. Neurologist. 2008 Sep; 14 (5):299-306
    View PubMed
  880. Vemuri P, Whitwell JL, Kantarci K, Josephs KA, Parisi JE, Shiung MS, Knopman DS, Boeve BF, Petersen RC, Dickson DW, Jack CR Jr. Antemortem MRI based STructural Abnormality iNDex (STAND)-scores correlate with postmortem Braak neurofibrillary tangle stage. Neuroimage. 2008 Aug 15; 42 (2):559-67 Epub 2008 May 20
    View PubMed
  881. Knopman DS, Mosley TH Jr, Bailey KR, Jack CR Jr, Schwartz GL, Turner ST. Associations of microalbuminuria with brain atrophy and white matter hyperintensities in hypertensive sibships. J Neurol Sci. 2008 Aug 15; 271 (1-2):53-60 Epub 2008 Apr 28
    View PubMed
  882. Hu WT, Josephs KA, Knopman DS, Boeve BF, Dickson DW, Petersen RC, Parisi JE. Temporal lobar predominance of TDP-43 neuronal cytoplasmic inclusions in Alzheimer disease. Acta Neuropathol. 2008 Aug; 116 (2):215-20 Epub 2008 July 01
    View PubMed
  883. Roberts RO, Geda YE, Knopman DS, Christianson TJ, Pankratz VS, Boeve BF, Vella A, Rocca WA, Petersen RC. Association of duration and severity of diabetes mellitus with mild cognitive impairment. Arch Neurol. 2008 Aug; 65 (8):1066-73
    View PubMed
  884. Fujishiro H, Ferman TJ, Boeve BF, Smith GE, Graff-Radford NR, Uitti RJ, Wszolek ZK, Knopman DS, Petersen RC, Parisi JE, Dickson DW. Validation of the neuropathologic criteria of the third consortium for dementia with Lewy bodies for prospectively diagnosed cases. J Neuropathol Exp Neurol. 2008 Jul; 67 (7):649-56
    View PubMed
  885. Kantarci K, Knopman DS, Dickson DW, Parisi JE, Whitwell JL, Weigand SD, Josephs KA, Boeve BF, Petersen RC, Jack CR Jr. Alzheimer disease: postmortem neuropathologic correlates of antemortem 1H MR spectroscopy metabolite measurements. Radiology. 2008 Jul; 248 (1):210-20
    View PubMed
  886. Karlawish J, Kim SY, Knopman D, van Dyck CH, James BD, Marson D. Interpreting the clinical significance of capacity scores for informed consent in Alzheimer disease clinical trials. Am J Geriatr Psychiatry. 2008 Jul; 16(7):568-74. Epub 2008 Jun 12.
    View PubMed
  887. Josephs KA, Whitwell JL, Knopman DS, Hu WT, Stroh DA, Baker M, Rademakers R, Boeve BF, Parisi JE, Smith GE, Ivnik RJ, Petersen RC, Jack CR Jr, Dickson DW. Abnormal TDP-43 immunoreactivity in AD modifies clinicopathologic and radiologic phenotype. Neurology. 2008 May 6; 70 (19 Pt 2):1850-7 Epub 2008 Apr 09
    View PubMed
  888. Jack CR Jr, Weigand SD, Shiung MM, Przybelski SA, O'Brien PC, Gunter JL, Knopman DS, Boeve BF, Smith GE, Petersen RC. Atrophy rates accelerate in amnestic mild cognitive impairment. Neurology. 2008 May 6; 70 (19 Pt 2):1740-52 Epub 2007 Nov 21
    View PubMed
  889. Josephs KA, Whitwell JL, Parisi JE, Knopman DS, Boeve BF, Geda YE, Jack CR Jr, Petersen RC, Dickson DW. Argyrophilic grains: a distinct disease or an additive pathology? Neurobiol Aging. 2008 Apr; 29 (4):566-73 Epub 2006 Dec 26
    View PubMed
  890. Jack CR Jr, Lowe VJ, Senjem ML, Weigand SD, Kemp BJ, Shiung MM, Knopman DS, Boeve BF, Klunk WE, Mathis CA, Petersen RC. 11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment. Brain. 2008 Mar; 131 (Pt 3):665-80 Epub 2008 Feb 07
    View PubMed
  891. Karlawish J, Kim SY, Knopman D, van Dyck CH, James BD, Marson D. The views of Alzheimer disease patients and their study partners on proxy consent for clinical trial enrollment. Am J Geriatr Psychiatry. 2008 Mar; 16(3):240-7.
    View PubMed
  892. Whitwell JL, Shiung MM, Przybelski SA, Weigand SD, Knopman DS, Boeve BF, Petersen RC, Jack CR Jr. MRI patterns of atrophy associated with progression to AD in amnestic mild cognitive impairment. Neurology. 2008 Feb 12; 70 (7):512-20 Epub 2007 Sept 26
    View PubMed
  893. Josephs KA, Whitwell JL, Ahmed Z, Shiung MM, Weigand SD, Knopman DS, Boeve BF, Parisi JE, Petersen RC, Dickson DW, Jack CR Jr. Beta-amyloid burden is not associated with rates of brain atrophy. Ann Neurol. 2008 Feb; 63 (2):204-12
    View PubMed
  894. Josephs KA, Whitwell JL, Dickson DW, Boeve BF, Knopman DS, Petersen RC, Parisi JE, Jack CR Jr. Voxel-based morphometry in autopsy proven PSP and CBD. Neurobiol Aging. 2008 Feb; 29 (2):280-9 Epub 2006 Nov 13
    View PubMed
  895. Vemuri P, Gunter JL, Senjem ML, Whitwell JL, Kantarci K, Knopman DS, Boeve BF, Petersen RC, Jack CR Jr. Alzheimer's disease diagnosis in individual subjects using structural MR images: validation studies. Neuroimage. 2008 Feb 1; 39 (3):1186-97 Epub 2007 Oct 22
    View PubMed
  896. Whitwell JL, Jack CR Jr, Pankratz VS, Parisi JE, Knopman DS, Boeve BF, Petersen RC, Dickson DW, Josephs KA. Rates of brain atrophy over time in autopsy-proven frontotemporal dementia and Alzheimer disease. Neuroimage. 2008 Feb 1; 39 (3):1034-40 Epub 2007 Oct 10
    View PubMed
  897. Murray ME, Knopman DS, Dickson DW. Vascular dementia: clinical, neuroradiologic and neuropathologic aspects. Panminerva Med. 2007 Dec; 49: (4)197-207.
    View PubMed
  898. Knopman DS. Cerebrovascular disease and dementia. Br J Radiol. 2007 Dec; 80 Spec No 2:S121-7
    View PubMed
  899. Geda YE, Boeve BF, Negash S, Graff-Radford NR, Knopman DS, Parisi JE, Dickson DW, Petersen RC. Neuropsychiatric features in 36 pathologically confirmed cases of corticobasal degeneration. J Neuropsychiatry Clin Neurosci. 2007 Winter; 19 (1):77-80
    View PubMed
  900. Hu WT, Mandrekar JN, Parisi JE, Knopman DS, Boeve BF, Petersen RC, Hutton M, Dickson DW, Josephs KA. Clinical features of pathologic subtypes of behavioral--variant frontotemporal dementia. Arch Neurol. 2007 Nov; 64 (11):1611-6
    View PubMed
  901. Rascovsky K, Hodges JR, Kipps CM, Johnson JK, Seeley WW, Mendez MF, Knopman D, Kertesz A, Mesulam M, Salmon DP, Galasko D, Chow TW, Decarli C, Hillis A, Josephs K, Kramer JH, Weintraub S, Grossman M, Gorno-Tempini ML, Miller BM. Diagnostic criteria for the behavioral variant of frontotemporal dementia (bvFTD): current limitations and future directions. Alzheimer Dis Assoc Disord. 2007 Oct-Dec; 21(4):S14-8.
    View PubMed
  902. Knopman DS, Boeve BS, Caselli RJ, Graff-Radford NR, Kramer JH, Mendez MF, Miller BL. Longitudinal tracking of FTLD: toward developing clinical trial methodology. Alzheimer Dis Assoc Disord. 2007 Oct-Dec; 21 (4):S58-63
    View PubMed
  903. Hu WT, Parisi JE, Knopman DS, Boeve BF, Dickson DW, Ahlskog JE, Petersen RC, Josephs KA. Clinical features and survival of 3R and 4R tauopathies presenting as behavioral variant frontotemporal dementia. Alzheimer Dis Assoc Disord. 2007 Oct-Dec; 21(4):S39-43.
    View PubMed
  904. Rademakers R, Baker M, Gass J, Adamson J, Huey ED, Momeni P, Spina S, Coppola G, Karydas AM, Stewart H, Johnson N, Hsiung GY, Kelley B, Kuntz K, Steinbart E, Wood EM, Yu CE, Josephs K, Sorenson E, Womack KB, Weintraub S, Pickering-Brown SM, Schofield PR, Brooks WS, Van Deerlin VM, Snowden J, Clark CM, Kertesz A, Boylan K, Ghetti B, Neary D, Schellenberg GD, Beach TG, Mesulam M, Mann D, Grafman J, Mackenzie IR, Feldman H, Bird T, Petersen R, Knopman D, Boeve B, Geschwind DH, Miller B, Wszolek Z, Lippa C, Bigio EH, Dickson D, Graff-Radford N, Hutton M. Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C-->T (Arg493X) mutation: an international initiative. Lancet Neurol. 2007 Oct; 6 (10):857-68
    View PubMed
  905. Kantarci K, Weigand SD, Petersen RC, Boeve BF, Knopman DS, Gunter J, Reyes D, Shiung M, O'Brien PC, Smith GE, Ivnik RJ, Tangalos EG, Jack CR Jr. Longitudinal 1H MRS changes in mild cognitive impairment and Alzheimer's disease. Neurobiol Aging. 2007 Sep; 28 (9):1330-9 Epub 2006 July 24
    View PubMed
  906. Knopman DS, Edland SD, Cha RH, Petersen RC, Rocca WA. Incident dementia in women is preceded by weight loss by at least a decade. Neurology. 2007 Aug 21; 69 (8):739-46
    View PubMed
  907. Whitwell JL, Petersen RC, Negash S, Weigand SD, Kantarci K, Ivnik RJ, Knopman DS, Boeve BF, Smith GE, Jack CR Jr. Patterns of atrophy differ among specific subtypes of mild cognitive impairment. Arch Neurol. 2007 Aug; 64 (8):1130-8
    View PubMed
  908. Smith GE, Pankratz VS, Negash S, Machulda MM, Petersen RC, Boeve BF, Knopman DS, Lucas JA, Ferman TJ, Graff-Radford N, Ivnik RJ. A plateau in pre-Alzheimer memory decline: evidence for compensatory mechanisms? Neurology. 2007 Jul 10; 69 (2):133-9
    View PubMed
  909. Whitwell JL, Jack CR Jr, Kantarci K, Weigand SD, Boeve BF, Knopman DS, Drubach DA, Tang-Wai DF, Petersen RC, Josephs KA. Imaging correlates of posterior cortical atrophy. Neurobiol Aging. 2007 Jul; 28 (7):1051-61 Epub 2006 June 23
    View PubMed
  910. Whitwell JL, Przybelski SA, Weigand SD, Knopman DS, Boeve BF, Petersen RC, Jack CR Jr. 3D maps from multiple MRI illustrate changing atrophy patterns as subjects progress from mild cognitive impairment to Alzheimer's disease. Brain. 2007 Jul; 130 (Pt 7):1777-86 Epub 2007 May 28
    View PubMed
  911. Negash S, Boeve BF, Geda YE, Smith GE, Knopman DS, Ivnik RJ, Howard DV, Howard JH Jr, Petersen RC. Implicit learning of sequential regularities and spatial contexts in corticobasal syndrome. Neurocase. 2007 Jun; 13(3):133-43.
    View PubMed
  912. Negash S, Petersen LE, Geda YE, Knopman DS, Boeve BF, Smith GE, Ivnik RJ, Howard DV, Howard JH Jr, Petersen RC. Effects of ApoE genotype and mild cognitive impairment on implicit learning. Neurobiol Aging. 2007 Jun; 28(6):885-93. Epub 2006 May 15.
    View PubMed
  913. Schwartz GL, Bailey KR, Mosley T, Knopman DS, Jack CR Jr, Canzanello VJ, Turner ST. Association of ambulatory blood pressure with ischemic brain injury. Hypertension. 2007 Jun; 49 (6):1228-34 Epub 2007 Apr 02
    View PubMed
  914. Machulda MM, Ivnik RJ, Smith GE, Ferman TJ, Boeve BF, Knopman D, Knopman D, Petersen RC, Tangalos EG. Mayo's Older Americans Normative Studies: Visual Form Discrimination and copy trial of the Rey-Osterrieth Complex Figure. J Clin Exp Neuropsychol. 2007 May; 29 (4):377-84
    View PubMed
  915. Cerhan JH, Ivnik RJ, Smith GE, Machulda MM, Boeve BF, Knopman DS, Petersen RC, Tangalos EG. Alzheimer's disease patients' cognitive status and course years prior to symptom recognition. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2007 May; 14 (3):227-35
    View PubMed
  916. Whitwell JL, Jack CR Jr, Parisi JE, Knopman DS, Boeve BF, Petersen RC, Ferman TJ, Dickson DW, Josephs KA. Rates of cerebral atrophy differ in different degenerative pathologies. Brain. 2007 Apr; 130 (Pt 4):1148-58 Epub 2007 Mar 08
    View PubMed
  917. Whitwell JL, Jack CR Jr, Baker M, Rademakers R, Adamson J, Boeve BF, Knopman DS, Parisi JF, Petersen RC, Dickson DW, Hutton ML, Josephs KA. Voxel-based morphometry in frontotemporal lobar degeneration with ubiquitin-positive inclusions with and without progranulin mutations. Arch Neurol. 2007 Mar; 64 (3):371-6
    View PubMed
  918. Whitwell JL, Weigand SD, Shiung MM, Boeve BF, Ferman TJ, Smith GE, Knopman DS, Petersen RC, Benarroch EE, Josephs KA, Jack CR Jr. Focal atrophy in dementia with Lewy bodies on MRI: a distinct pattern from Alzheimer's disease. Brain. 2007 Mar; 130 (Pt 3):708-19 Epub 2007 Jan 31
    View PubMed
  919. Graff-Radford NR, Crook JE, Lucas J, Boeve BF, Knopman DS, Ivnik RJ, Smith GE, Younkin LH, Petersen RC, Younkin SG. Association of low plasma Abeta42/Abeta40 ratios with increased imminent risk for mild cognitive impairment and Alzheimer disease. Arch Neurol. 2007 Mar; 64 (3):354-62
    View PubMed
  920. Josephs KA, Ahmed Z, Katsuse O, Parisi JF, Boeve BF, Knopman DS, Petersen RC, Davies P, Duara R, Graff-Radford NR, Uitti RJ, Rademakers R, Adamson J, Baker M, Hutton ML, Dickson DW. Neuropathologic features of frontotemporal lobar degeneration with ubiquitin-positive inclusions with progranulin gene (PGRN) mutations. J Neuropathol Exp Neurol. 2007 Feb; 66 (2):142-51
    View PubMed
  921. Ferman TJ, Smith GE, Boeve BF, Graff-Radford NR, Lucas JA, Knopman DS, Petersen RC, Ivnik RJ, Wszolek Z, Uitti R, Dickson DW. Neuropsychological differentiation of dementia with Lewy bodies from normal aging and Alzheimer's disease. Clin Neuropsychol. 2006 Dec; 20 (4):623-36
    View PubMed
  922. Knopman D. Pinpointing the cause of non-Alzheimer dementia. Psychiatric Times. 2006 Nov; 23(13):37-8, 40.
  923. Boeve BF, Baker M, Dickson DW, Parisi JE, Giannini C, Josephs KA, Hutton M, Pickering-Brown SM, Rademakers R, Tang-Wai D, Jack CR Jr, Kantarci K, Shiung MM, Golde T, Smith GE, Geda YE, Knopman DS, Petersen RC. Frontotemporal dementia and parkinsonism associated with the IVS1+1G->A mutation in progranulin: a clinicopathologic study. Brain. 2006 Nov; 129 (Pt 11):3103-14 Epub 2006 Oct 09
    View PubMed
  924. Gass J, Cannon A, Mackenzie IR, Boeve B, Baker M, Adamson J, Crook R, Melquist S, Kuntz K, Petersen R, Josephs K, Pickering-Brown SM, Graff-Radford N, Uitti R, Dickson D, Wszolek Z, Gonzalez J, Beach TG, Bigio E, Johnson N, Weintraub S, Mesulam M, White CL 3rd, Woodruff B, Caselli R, Hsiung GY, Feldman H, Knopman D, Hutton M, Rademakers R. Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration. Hum Mol Genet. 2006 Oct 15; 15 (20):2988-3001 Epub 2006 Sept 01
    View PubMed
  925. Josephs KA, Whitwell JL, Boeve BF, Knopman DS, Tang-Wai DF, Drubach DA, Jack CR Jr, Petersen RC. Visual hallucinations in posterior cortical atrophy. Arch Neurol. 2006 Oct; 63 (10):1427-32
    View PubMed
  926. Knopman DS. Current treatment of mild cognitive impairment and Alzheimer's disease. Curr Neurol Neurosci Rep. 2006 Sep; 6 (5):365-71
    View PubMed
  927. Petersen RC, Knopman DS. MCI is a clinically useful concept. Int Psychogeriatr. 2006 Sep; 18: (3)394-402; discussion 409-14.
    View PubMed
  928. Murray AM, Tupper DE, Knopman DS, Gilbertson DT, Pederson SL, Li S, Smith GE, Hochhalter AK, Collins AJ, Kane RL. Cognitive impairment in hemodialysis patients is common. Neurology. 2006 Jul 25; 67(2):216-23.
    View PubMed
  929. Knopman D. Finding potent drugs for Alzheimer's disease is more important than proving the drugs are disease modifying. Alzheimers Dement. 2006 Jul; 2(3):147-9.
    View PubMed
  930. Suravarapu S, Bergstralh EJ, Farmer SA, Knopman DS, Jacobsen SJ, Roberts RO. Dementia and low testosterone and bioavailable testosterone levels in men: possible increased risk. Alzheimer Dis Assoc Disord. 2006 Jul-Sep; 20 (3):138-40
    View PubMed
  931. Roberts RO, Cha RH, Knopman DS, Petersen RC, Rocca WA. Postmenopausal estrogen therapy and Alzheimer disease: overall negative findings. Alzheimer Dis Assoc Disord. 2006 Jul-Sep; 20 (3):141-6
    View PubMed
  932. Josephs KA, Duffy JR, Strand EA, Whitwell JL, Layton KF, Parisi JE, Hauser MF, Witte RJ, Boeve BF, Knopman DS, Dickson DW, Jack CR Jr, Petersen RC. Clinicopathological and imaging correlates of progressive aphasia and apraxia of speech. Brain. 2006 Jun; 129 (Pt 6):1385-98 Epub 2006 Apr 13
    View PubMed
  933. Jicha GA, Petersen RC, Knopman DS, Boeve BF, Smith GE, Geda YE, Johnson KA, Cha R, Delucia MW, Braak H, Dickson DW, Parisi JE. Argyrophilic grain disease in demented subjects presenting initially with amnestic mild cognitive impairment. J Neuropathol Exp Neurol. 2006 Jun; 65(6):602-9.
    View PubMed
  934. Powell MR, Smith GE, Knopman DS, Parisi JE, Boeve BF, Petersen RC, Ivnik RJ. Cognitive measures predict pathologic Alzheimer disease. Arch Neurol. 2006 Jun; 63(6):865-8.
    View PubMed
  935. Petersen RC, Parisi JE, Dickson DW, Johnson KA, Knopman DS, Boeve BF, Jicha GA, Ivnik RJ, Smith GE, Tangalos EG, Braak H, Kokmen E. Neuropathologic features of amnestic mild cognitive impairment. Arch Neurol. 2006 May; 63 (5):665-72
    View PubMed
  936. Cannon A, Baker M, Boeve B, Josephs K, Knopman D, Petersen R, Parisi J, Dickison D, Adamson J, Snowden J, Neary D, Mann D, Hutton M, Pickering-Brown SM. CHMP2B mutations are not a common cause of frontotemporal lobar degeneration. Neurosci Lett. 2006 May 1; 398 (1-2):83-4 Epub 2006 Jan 23
    View PubMed
  937. Jicha GA, Parisi JE, Dickson DW, Johnson K, Cha R, Ivnik RJ, Tangalos EG, Boeve BF, Knopman DS, Braak H, Petersen RC. Neuropathologic outcome of mild cognitive impairment following progression to clinical dementia. Arch Neurol. 2006 May; 63(5):674-81.
    View PubMed
  938. Josephs KA, Parisi JE, Knopman DS, Boeve BF, Petersen RC, Dickson DW. Clinically undetected motor neuron disease in pathologically proven frontotemporal lobar degeneration with motor neuron disease. Arch Neurol. 2006 Apr; 63(4):506-12.
    View PubMed
  939. Geda YE, Knopman DS, Mrazek DA, Jicha GA, Smith GE, Negash S, Boeve BF, Ivnik RJ, Petersen RC, Pankratz VS, Rocca WA. Depression, apolipoprotein E genotype, and the incidence of mild cognitive impairment: a prospective cohort study. Arch Neurol. 2006 Mar; 63 (3):435-40
    View PubMed
  940. Siemers ER, Quinn JF, Kaye J, Farlow MR, Porsteinsson A, Tariot P, Zoulnouni P, Galvin JE, Holtzman DM, Knopman DS, Satterwhite J, Gonzales C, Dean RA, May PC. Effects of a gamma-secretase inhibitor in a randomized study of patients with Alzheimer disease. Neurology. 2006 Feb 28; 66(4):602-4.
    View PubMed
  941. Knopman DS. Dementia and cerebrovascular disease. Mayo Clin Proc. 2006 Feb; 81 (2):223-30
    View PubMed
  942. Knopman DS, Petersen RC, Cha RH, Edland SD, Rocca WA. Incidence and causes of nondegenerative nonvascular dementia: a population-based study. Arch Neurol. 2006 Feb; 63 (2):218-21
    View PubMed
  943. Bursi F, Rocca WA, Killian JM, Weston SA, Knopman DS, Jacobsen SJ, Roger VL. Heart disease and dementia: a population-based study. Am J Epidemiol. 2006 Jan 15; 163(2):135-41. Epub 2005 Nov 17.
    View PubMed
  944. Josephs KA, Petersen RC, Knopman DS, Boeve BF, Whitwell JL, Duffy JR, Parisi JE, Dickson DW. Clinicopathologic analysis of frontotemporal and corticobasal degenerations and PSP. Neurology. 2006 Jan 10; 66 (1):41-8
    View PubMed
  945. Jack CR Jr, Shiung MM, Weigand SD, O'Brien PC, Gunter JL, Boeve BF, Knopman DS, Smith GE, Ivnik RJ, Tangalos EG, Petersen RC. Brain atrophy rates predict subsequent clinical conversion in normal elderly and amnestic MCI. Neurology. 2005 Oct 25; 65 (8):1227-31
    View PubMed
  946. Knopman DS, Petersen RC, Cha RH, Edland SD, Rocca WA. Coronary artery bypass grafting is not a risk factor for dementia or Alzheimer disease. Neurology. 2005 Oct 11; 65: (7)986-90.
    View PubMed
  947. Knopman DS, Mosley TH, Catellier DJ, Sharrett AR. Cardiovascular risk factors and cerebral atrophy in a middle-aged cohort. Neurology. 2005 Sep 27; 65(6):876-81.
  948. Tuite PJ, Clark HB, Bergeron C, Bower M, St George-Hyslop P, Mateva V, Anderson J, Knopman DS. Clinical and pathologic evidence of corticobasal degeneration and progressive supranuclear palsy in familial tauopathy. Arch Neurol. 2005 Sep; 62(9):1453-7.
    View PubMed
  949. Josephs KA, Knopman DS, Whitwell JL, Boeve BF, Parisi JE, Petersen RC, Dickson DW. Survival in two variants of tau-negative frontotemporal lobar degeneration: FTLD-U vs FTLD-MND. Neurology. 2005 Aug 23; 65(4):645-7.
    View PubMed
  950. Josephs KA, Boeve BF, Duffy JR, Smith GE, Knopman DS, Parisi JE, Petersen RC, Dickson DW. Atypical progressive supranuclear palsy underlying progressive apraxia of speech and nonfluent aphasia. Neurocase. 2005 Aug; 11 (4):283-96
    View PubMed
  951. Knopman D. Commentary: "Treatment of hypertension and prevention of dementia" by Oliver Hanon and Francoise Forette. Alzheimers Dement. 2005 Jul; 1(1):41-2.
    View PubMed
  952. Mosley TH, Knopman DS, Catellier DJ, Bryan N, Hutchinson RG, Grothues CA, Folsom AR, Cooper LS, Burke GL, Liao D, Szklo M. Cerebral MRI findings and cognitive functioning - The atherosclerosis risk in communities study. Neurology. 2005 Jun 28; 64(12):2056-62.
    View PubMed
  953. Rippon GA, Boeve BF, Parisi JE, Dickson DW, Ivnik RI, Jack CR, Hutton M, Baker M, Josephs KA, Knopman DS, Petersen RC. Late-onset frontotemporal dementia associated with progressive supranuclear palsy/argyrophilic grain disease/Alzheimer's disease pathology. Neurocase. 2005 Jun; 11(3):204-11.
    View PubMed
  954. Elkins JS, Knopman DS, Yaffe K, Johnston SC. Cognitive function predicts first-time stroke and heart disease. Neurology. 2005 May 24; 64(10):1750-5.
    View PubMed
  955. Knopman DS, Boeve BF, Parisi JE, Dickson DW, Smith GE, Ivnik RJ, Josephs KA, Petersen RC. Antemortem diagnosis of frontotemporal lobar degeneration. Ann Neurol. 2005 Apr; 57 (4):480-8
    View PubMed
  956. Kantarci K, Petersen RC, Boeve BF, Knopman DS, Weigand SD, O'Brien PC, Shiung MM, Smith GE, Ivnik RJ, Tangalos EG, Jack CR Jr. DWI predicts future progression to Alzheimer disease in amnestic mild cognitive impairment. Neurology. 2005 Mar 8; 64 (5):902-4
    View PubMed
  957. Blair CK, Folsom AR, Knopman DS, Bray MS, Mosley TH, Boerwinkle E. APOE genotype and cognitive decline in a middle-aged cohort. Neurology. 2005 Jan 25; 64(2):268-76.
    View PubMed
  958. Kantarci K, Petersen RC, Boeve BF, Knopman DS, Tang-Wai DF, O'Brien PC, Weigand SD, Edland SD, Smith GE, Ivnik RJ, Ferman TJ, Tangalos EG, Jack CR Jr. 1H MR spectroscopy in common dementias. Neurology. 2004 Oct 26; 63 (8):1393-8
    View PubMed
  959. Kantarci K, Petersen RC, Boeve BF, Knopman DS, Tang-Wai DF, O'Brien PC, Weigand SD, Edland SD, Smith GE, Ivnik RJ, Ferman TJ, Tangalos EG, Jack CR. H-1 MR spectroscopy in common dementias. Neurology. 2004 Oct 26; 63(8):1393-8.
  960. Tang-Wai DF, Graff-Radford NR, Boeve BF, Dickson DW, Parisi JE, Crook R, Caselli RJ, Knopman DS, Petersen RC. Clinical, genetic, and neuropathologic characteristics of posterior cortical atrophy. Neurology. 2004 Oct 12; 63 (7):1168-74
    View PubMed
  961. Karlawish JH, Bonnie RJ, Appelbaum PS, Lyketsos C, James B, Knopman D, Patusky C, Kane RA, Karlan PS. Addressing the ethical, legal, and social issues raised by voting by persons with dementia. JAMA. 2004 Sep 15; 292(11):1345-50.
    View PubMed
  962. Testa JA, Ivnik RJ, Boeve B, Petersen RC, Pankratz VS, Knopman D, Tangalos E, Smith GE. Confrontation naming does not add incremental diagnostic utility in MCI and Alzheimer's disease. J Int Neuropsychol Soc. 2004 Jul; 10 (4):504-12
    View PubMed
  963. Geda YE, Smith GE, Knopman DS, Boeve BF, Tangalos EG, Ivnik RJ, Mrazek DA, Edland SD, Petersen RC. De novo genesis of neuropsychiatric symptoms in mild cognitive impairment (MCI). Int Psychogeriatr. 2004 Mar; 16 (1):51-60
    View PubMed
  964. Jack CR Jr, Shiung MM, Gunter JL, O'Brien PC, Weigand SD, Knopman DS, Boeve BF, Ivnik RJ, Smith GE, Cha RH, Tangalos EG, Petersen RC. Comparison of different MRI brain atrophy rate measures with clinical disease progression in AD. Neurology. 2004 Feb 24; 62(4):591-600.
    View PubMed
  965. Knopman DS, Petersen RC, Edland SD, Cha RH, Rocca WA. The incidence of frontotemporal lobar degeneration in Rochester, Minnesota, 1990 through 1994. Neurology. 2004 Feb 10; 62 (3):506-8
    View PubMed
  966. Ferman TJ, Smith GE, Boeve BF, Ivnik RJ, Petersen RC, Knopman D, Knopman D, Graff-Radford N, Parisi J, Parisi J, Dickson DW. DLB fluctuations: specific features that reliably differentiate DLB from AD and normal aging. Neurology. 2004 Jan 27; 62 (2):181-7
    View PubMed
  967. Tang-Wai DF, Knopman DS, Geda YE, Edland SD, Smith GE, Ivnik RJ, Tangalos EG, Boeve BF, Petersen RC. Comparison of the short test of mental status and the mini-mental state examination in mild cognitive impairment. Arch Neurol. 2003 Dec; 60 (12):1777-81
    View PubMed
  968. Clark CM, Xie S, Chittams J, Ewbank D, Peskind E, Galasko D, Morris JC, McKeel DW, Farlow M, Weitlauf SL, Quinn J, Kaye J, Knopman D, Arai H, Doody RS, DeCarli C, Leight S, Lee VMY, Trojanowski JQ. Cerebrospinal fluid tau and beta-amyloid - How well do these biomarkers reflect autopsy-confirmed dementia diagnoses? Arch Neurol. 2003 Dec; 60(12):1696-702.
    View PubMed
  969. Knopman DS, Parisi JE, Salviati A, Floriach-Robert M, Boeve BF, Ivnik RJ, Smith GE, Dickson DW, Johnson KA, Petersen LE, McDonald WC, Braak H, Petersen RC. Neuropathology of cognitively normal elderly. J Neuropathol Exp Neurol. 2003 Nov; 62 (11):1087-95
    View PubMed
  970. de Moraes SA, Szklo M, Tilling K, Sato R, Knopman D. Cognitive functioning as a predictor of ischemic stroke incidence. Epidemiology. 2003 Nov; 14(6):673-9.
    View PubMed
  971. Knopman DS, Boeve BF, Petersen RC. Essentials of the proper diagnoses of mild cognitive impairment, dementia, and major subtypes of dementia. Mayo Clin Proc. 2003 Oct; 78(10):1290-308.
    View PubMed
  972. Machulda MM, Ward HA, Borowski B, Gunter JL, Cha RH, O'Brien PC, Petersen RC, Boeve BF, Knopman D, Tang-Wai DF, Ivnik RJ, Smith GE, Tangalos EG, Jack CR Jr. Comparison of memory fMRI response among normal, MCI, and Alzheimer's patients. Neurology. 2003 Aug 26; 61(4):500-6.
    View PubMed
  973. Boeve BF, Silber MH, Parisi JE, Dickson DW, Ferman TJ, Benarroch EE, Schmeichel AM, Smith GE, Petersen RC, Ahlskog JE, Matsumoto JY, Knopman DS, Schenck CH, Mahowald MW. Synucleinopathy pathology and REM sleep behavior disorder plus dementia or parkinsonism. Neurology. 2003 Jul 8; 61 (1):40-5
    View PubMed
  974. Kantarci K, Reynolds G, Petersen RC, Boeve BF, Knopman DS, Edland SD, Smith GE, Ivnik RJ, Tangalos EG, Jack CR Jr. Proton MR spectroscopy in mild cognitive impairment and Alzheimer disease: comparison of 1.5 and 3 T. AJNR Am J Neuroradiol. 2003 May; 24: (5)843-9.
    View PubMed
  975. Knopman DS, Parisi JE, Boeve BF, Cha RH, Apaydin H, Salviati A, Edland SD, Rocca WA. Vascular dementia in a population-based autopsy study. Arch Neurol. 2003 Apr; 60 (4):569-75
    View PubMed
  976. Knopman D. Pharmacotherapy for Alzheimer's disease: 2002. Clin Neuropharmacol. 2003 Mar-Apr; 26 (2):93-101
    View PubMed
  977. Boeve B, McCormick J, Boeve B, Smith G, Ferman T, Smith G, Rummans T, Carpenter T, Rummans T, Ivnik R, Kokmen E, Ivnik R, Tangalos E, Edland S, Tangalos E, Edland S, Knopman D, Petersen R, Knopman D, Petersen R. Mild cognitive impairment in the oldest old. Neurology. 2003 Feb 11; 60 (3):477-80
    View PubMed
  978. Jack CR Jr, Slomkowski M, Gracon S, Hoover TM, Felmlee JP, Stewart K, Xu Y, Shiung M, Xu Y, O'Brien PC, Cha R, Knopman D, Petersen RC. MRI as a biomarker of disease progression in a therapeutic trial of milameline for AD. Neurology. 2003 Jan 28; 60 (2):253-60
    View PubMed
  979. Kantarci K, Smith GE, Ivnik RJ, Petersen RC, Boeve BF, Knopman DS, Tangalos EG, Jack CR Jr. 1H magnetic resonance spectroscopy, cognitive function, and apolipoprotein E genotype in normal aging, mild cognitive impairment and Alzheimer's disease. J Int Neuropsychol Soc. 2002 Nov; 8 (7):934-42
    View PubMed
  980. Kantarci K, Smith GE, Ivnik RJ, Petersen RC, Boeve BF, Knopman DS, Tangalos EG, Jack CR. H-1 magnetic resonance spectroscopy, cognitive function, and apolipoprotein E genotype in normal aging, mild cognitive impairment and Alzheimer's disease. J Int Neuropsychol Soc. 2002 Nov; 8(7):934-42.
  981. Knopman DS, Rocca WA, Cha RH, Edland SD, Kokmen E. Incidence of vascular dementia in Rochester, Minn, 1985-1989. Arch Neurol. 2002 Oct; 59 (10):1605-10
    View PubMed
  982. Boland LL, Shahar E, Iber C, Knopman DS, Kuo TF, Nieto FJ. Measures of cognitive function in persons with varying degrees of sleep-disordered breathing: the Sleep Heart Health Study. J Sleep Res. 2002 Sep; 11(3):265-72.
    View PubMed
  983. de Moraes SA, Szklo M, Knopman D, Sato R. The relationship between temporal changes in blood pressure and changes in cognitive function: Atherosclerosis Risk in Communities (ARIC) Study. Prev Med. 2002 Sep; 35(3):258-63.
    View PubMed
  984. Karlawish JHT, Knopman D, Clark CM, Morris JC, Marson D, Whitehouse PJ, Kawas CH. Informed consent for Alzheimer's disease clinical trials: a survey of clinical investigators. IRB. 2002 Sep-Oct; 24(5):1-5.
  985. Knopman DS, von Sternberg T, Haefemeyer JW. Telephonic screening for cognitive impairment: a feasibility study in a managed care clinic. Journal of Clinical Outcomes Management. 2002 Mar; 9(3):129-33.
  986. Quinn J, Moore M, Benson DF, Clark CM, Doody R, Jagust W, Knopman D, Kaye JA. A Videotaped CIBIC for dementia patients - Validity and reliability in a simulated clinical trial. Neurology. 2002 Feb 12; 58(3):433-7.
    View PubMed
  987. de Moraes SA, Szklo M, Knopman D, Park E. Prospective assessment of estrogen replacement therapy and cognitive functioning: atherosclerosis risk in communities study. Am J Epidemiol. 2001 Oct 15; 154(8):733-9.
    View PubMed
  988. Kato T, Knopman D, Liu H. Dissociation of regional activation in mild AD during visual encoding: a functional MRI study. Neurology. 2001 Sep 11; 57(5):812-6.
    View PubMed
  989. Knopman D. Pharmacotheraphy for Alzheimer's disease. Curr Neurol Neurosci Rep. 2001 Sep; 1 (5):428-34
    View PubMed
  990. Rice DP, Fillit HM, Max W, Knopman DS, Lloyd JR, Duttagupta S. Prevalence, costs, and treatment of Alzheimer's disease and related dementia: a managed care perspective. Am J Manag Care. 2001 Aug; 7(8):809-18.
    View PubMed
  991. Knopman D, Patterson M, Knopman D. An open-label, 24-week pilot study of the methyl donor betaine in Alzheimer disease patients. Alzheimer Dis Assoc Disord. 2001 Jul-Sep; 15 (3):162-5
    View PubMed
  992. Knopman DS, DeKosky ST, Cummings JL, Chui H, Corey-Bloom J, Relkin N, Small GW, Miller B, Stevens JC. Practice parameter: diagnosis of dementia (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2001 May 8; 56 (9):1143-53
    View PubMed
  993. Knopman DS. An overview of common non-Alzheimer dementias. Clin Geriatr Med. 2001 May; 17 (2):281-301
    View PubMed
  994. Knopman D, Boland LL, Knopman D, Mosley T, Howard G, Liao D, Szklo M, McGovern P, Folsom AR, Atherosclerosis Risk in Communities (ARIC) Study Investigators. Cardiovascular risk factors and cognitive decline in middle-aged adults. Neurology. 2001 Jan 9; 56 (1):42-8
    View PubMed
  995. Knopman DS. Part VI. Primary drug therapies for Alzheimer's disease. Dis Mon. 2000 Nov; 46 (11):745-60
    View PubMed
  996. Knopman DS. Part VII. Treatment of Neuropsychiatric symptoms in Alzheimer's disease. Dis Mon. 2000 Nov; 46 (11):761-6
    View PubMed
  997. Knopman DS, Knudson D, Yoes ME, Weiss DJ. Development and standardization of a new telephonic cognitive screening test: the Minnesota Cognitive Acuity Screen (MCAS). Neuropsychiatry Neuropsychol Behav Neurol. 2000 Oct; 13 (4):286-96
    View PubMed
  998. Knopman DS, Berg JD, Thomas R, Grundman M, Thal LJ, Sano M. Nursing home placement is related to dementia progression: experience from a clinical trial. Alzheimer's Disease Cooperative Study. Neurology. 1999 Mar 10; 52(4):714-8.
    View PubMed
  999. Knopman D, Kahn J, Miles S. Clinical research designs for emerging treatments for Alzheimer disease: moving beyond placebo-controlled trials. Arch Neurol. 1998 Nov; 55(11):1425-9.
    View PubMed
  1000. Szklo M, Cerhan J, Diez-Roux AV, Chambless L, Cooper L, Folsom AR, Fried LP, Knopman D, Nieto FJ. Estrogen replacement therapy and cognitive functioning in the Atherosclerosis Risk in Communities (ARIC) Study. Am J Epidemiol. 1996 Dec 1; 144(11):1048-57.
    View PubMed
PST-20222037