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Talal Hilal, M.D.

  1. Hematologist / Oncologist

出版物

  1. Hampel PJ, Rabe KG, Wang Y, Hwang SR, Kenderian SS, Muchtar E, Leis JF, Koehler AB, Tsang M, Hilal T, Parrondo R, Bailen RJ, Schwager SM, Hanson CA, Braggio E, Slager SL, Shi M, Zepeda-Mendoza CJ, Van Dyke DL, Shanafelt TD, King RL, Call TG, Kay NE, Ding W, Parikh SA. Incidence of Richter transformation of chronic lymphocytic leukemia/small lymphocytic lymphoma in the targeted therapy era. Leukemia. 2024 Dec 10 [Epub ahead of print]
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  2. Aldoss I, Roloff GW, Faramand R, Kopmar NE, Lin C, Advani AS, Dekker SE, Gupta VK, O'Connor TE, Jeyakumar N, Muhsen IN, Valtis Y, Zhang A, Miller K, Sutherland K, Dykes KC, Ahmed M, Chen E, Zambrano H, Bradshaw D, Mercadal S, Schwartz MS, Tracy S, Dholaria B, Kubiak M, Mukherjee A, Majhail N, Battiwalla M, Mountjoy L, Malik SA, Mathews J, Shaughnessy P, Logan AC, Ladha A, Stefan M, Guzowski C, Hoeg RT, Hilal T, Moore J, Connor M, O'Dwyer KM, Hill LC, Tsai SB, Sasine J, Solh MM, Lee CJ, Kota VK, Koura D, Veeraputhiran M, Blunk B, Oliai C, Leonard JT, Frey NV, Park JH, Luskin MR, Bachanova V, Galal A, Bishop MR, Stock W, Cassaday RD, Pullarkat V, Shah BD, Muffly LS. Impact of prior inotuzumab ozogamicin treatment on brexucabtagene autoleucel outcomes in adults with B-cell ALL. Blood Adv. 2024 Dec 10; 8 (23):6139-6147
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  3. Islam N, Budvytyte L, Khera N, Hilal T. Disparities in Clinical Trial Enrollment- Focus on CAR-T and Bispecific Antibody Therapies. Curr Hematol Malig Rep. 2024 Dec 4; 20 (1):1 Epub 2024 Dec 04
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  4. Cartagena J, Deshpande A, Rosenthal A, Tsang M, Hilal T, Rimsza L, Kurzrock R, Munoz J. Measurable Residual Disease in Mantle Cell Lymphoma: The Unbearable Lightness of Being Undetectable. Curr Oncol Rep. 2024 Dec; 26 (12):1664-1674 Epub 2024 Dec 06
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  5. Pophali PA, Fein JA, Ahn KW, Allbee-Johnson M, Ahmed N, Awan FT, Farhan S, Grover NS, Hilal T, Iqbal M, Maakaron J, Modi D, Nasrollahi E, Schachter LG, Sauter C, Hamadani M, Herrera A, Shouval R, Shadman M. CD19-directed CART therapy for T-cell/histiocyte-rich large B-cell lymphoma. Blood Adv. 2024 Oct 22; 8 (20):5290-5296
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  6. Mountjoy L, Roloff GW, Aldoss I, Kopmar NE, Lin C, Dekker SE, Gupta VK, O'Connor TE, Jeyakumar N, Muhsen IN, Valtis Y, Ahmed N, Zhang A, Miller K, Dykes KC, Ahmed M, Chen EC, Mercadal S, Schwartz M, Tracy SI, Dholaria B, Mukherjee A, Battiwalla M, Logan AC, Ladha A, Guzowski C, Hoeg RT, Hilal T, Moore J, Connor MP, Hill LC, Tsai SB, Sasine JP, Solh MM, Kota VK, Koura D, Veeraputhiran M, Leonard JT, Frey NV, Park JH, Luskin MR, Bachanova V, Galal A, Pullarkat V, Stock W, Cassaday RD, Shah BD, Faramand R, Muffly L, ROCCA Consortium. Outcomes After Brexucabtagene Autoleucel Administered as a Standard Therapy for Adults With Relapsed/Refractory B-Cell ALL. J Clin Oncol. 2024 Oct 17; JCO2400321 [Epub ahead of print]
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  7. Zhao J, Zhang N, Hilal T, Griffin JM, Yabroff KR, Khera N. Health insurance literacy among patients receiving outpatient cancer treatment. Cancer. 2024 Oct 15; 130 (20):3480-3486 Epub 2024 July 17
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  8. Koehler AB, Rabe KG, Crusan DJ, Call TG, Achenbach SJ, Hampel PJ, Kenderian SS, Leis JF, Wang Y, Muchtar E, Tsang M, Hilal T, Parrondo R, Bailey KR, Ding W, Bailen R, Schwager SM, Shi M, Hanson CA, Slager SL, Kay NE, Ashrani AA, Parikh SA. Incidence, risk factors, and outcomes of patients with monoclonal B-cell lymphocytosis and chronic lymphocytic leukemia who develop venous thromboembolism. J Thromb Haemost. 2024 Sep 27 Epub 2024 Sept 27
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  9. Rios-Olais FA, McGary AK, Tsang M, Almader-Douglas D, Leis JF, Buras MR, Hilal T. Measurable Residual Disease and Clinical Outcomes in Chronic Lymphocytic Leukemia: A Systematic Review and Meta-Analysis. JAMA Oncol. 2024 Sep 1; 10 (9):1221-1227
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  10. Wonnaparhown A, Hilal T, Squire J, Freeman C, Fonseca R. IgG replacement in multiple myeloma. Blood Cancer J. 2024 Jul 25; 14 (1):124 Epub 2024 July 25
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  11. Cliff ERS, Hilal T, Kesselheim AS. Complicated regulatory decision-making following inconsistent trial results: the issue with ibrutinib for mantle cell lymphoma. Nat Rev Clin Oncol. 2024 Jan; 21 (1):1-2
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  12. Gaulin C, Craig F, Fortin Ensign S, Robetorye R, Gibson S, Kelemen K, Khera N, Leis J, Tsang M, Rosenthal A, Munoz J, Palmer J, Hilal T. Allogeneic hematopoietic stem cell transplantation in adults with dendritic/histiocytic neoplasms. Leuk Lymphoma 2023 Dec; 64 (14):2347-2350 Epub 2023 Sept 07
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  13. Lee MK, Durani U, Zhang N, Hilal T, Warsame RM, Borah B, Khera N, Griffin JM. Relationships Among Health Insurance Literacy, Financial Toxicity, and Sociodemographic Factors in Patients With Cancer. JCO Oncol Pract. 2023 Oct; 19 (10):888-898 Epub 2023 Aug 24
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  14. Rios-Olais FA, Hilal T. Measurable Residual Disease in Chronic Lymphocytic Leukemia: Current Understanding and Evolving Role in Clinical Practice. Curr Treat Options Oncol. 2023 Aug; 24 (8):907-928 Epub 2023 May 17
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  15. Abdo Y, Gibson GD, Jain SP, Milner CP, Hilal T. Treatment of Relapsed B/T-cell Mixed Phenotype Acute Leukemia With Blinatumomab. Cureus. 2023 Jun; 15 (6):e40661 Epub 2023 June 19
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  16. Hilal T, Mountjoy LJ. Allogeneic Hematopoietic Stem Cell Transplant for Diffuse Large B-Cell Lymphoma: Evolving Role in the Era of CAR T-Cell Therapy. Curr Oncol Rep. 2023 Jun; 25 (6):599-607 Epub 2023 Mar 28
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  17. Hilal T. In the trenches. Lancet Haematol. 2023 Mar; 10 (3):e164
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  18. Khera N, Zhang N, Hilal T, Durani U, Lee M, Padman R, Voleti S, Warsame RM, Borah BJ, Yabroff KR, Griffin JM. Association of Health Insurance Literacy With Financial Hardship in Patients With Cancer. JAMA Netw Open. 2022 Jul 1; 5 (7):e2223141 Epub 2022 July 01
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  19. Hilal T, Jain SP. Isolated CNS relapse of blastic plasmacytoid dendritic cell neoplasm. Blood. 2022 Feb 24; 139 (8):1255
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  20. Hilal T. On dialogue and its many forms. Lancet Haematol. 2021 Mar; 8 (3):e171
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  21. Mountjoy L, Sebastian S, Jain T, Hilal T, Gonzalez-Velez M, Girardo M, Ahmann G, Larsen J, Bergsagel L, Fonseca R. Prediction of immunomodulatory drugs (IMiDs) sensitivity in myeloma via determination of baseline anti-oxidative stress capacity. Leukemia 2020 Nov; 34 (11):3060-3063 Epub 2020 June 05
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  22. Hilal T. Tail events with cancer treatment. Lancet Haematol. 2020 Oct; 7 (10):e712
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  23. Hilal T, Gonzalez-Velez M, Prasad V. Limitations in Clinical Trials Leading to Anticancer Drug Approvals by the US Food and Drug Administration. JAMA Intern Med. 2020 Aug 1; 180 (8):1108-1115
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  24. Hilal T, Munoz J. Choosing Wisely(R) in Hematology: Have We Made a Difference? Curr Hematol Malig Rep. 2020 Aug; 15 (4):241-247
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  25. Hilal T. Gone But Here. Am J Hosp Palliat Care. 2020 Aug; 37 (8):659-660 Epub 2019 Oct 30
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  26. Sonbol MB, Halfdanarson TR, Hilal T. Assessment of Therapy-Related Myeloid Neoplasms in Patients With Neuroendocrine Tumors After Peptide Receptor Radionuclide Therapy: A Systematic Review. JAMA Oncol. 2020 Jul 1; 6 (7):1086-1092
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  27. Hilal T, Mi L, Ertz-Archambault NM, Almquist DR, Anderson KS, Gray RJ, Pockaj BA, Northfelt DW. Change in 21-gene Recurrence Score result after exposure to neo-adjuvant endocrine therapy in patients with operable breast cancer. Breast J. 2020 Jul; 26 (7):1449-1451 Epub 2019 Dec 26
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  28. Sonbol MB, Firwana BM, Hilal T, Murad MH. How to read a published clinical trial: A practical guide for clinicians. Avicenna J Med. 2020 Apr-Jun; 10 (2):68-75 Epub 2019 Apr 01
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  29. Verma A, Sharma A, Robetorye R, Porter A, Hilal T. Intravascular Large B-cell Lymphoma Associated with Systemic and Central Nervous System Hemophagocytic Lymphohistiocytosis: A Case Report. Perm J. 2020; 24 Epub 2019 Dec 06
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  30. Hilal T. Progress in acute myeloid leukaemia: small molecular inhibitors with small benefits. Ecancermedicalscience. 2020; 14:1015 Epub 2020 Feb 27
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  31. Sonbol MB, Jain T, Firwana B, Hilal T, Deleon T, Murad A, Murad MH, Khera N. Neutropenic diets to prevent cancer infections: updated systematic review and meta-analysis. BMJ Support Palliat Care. 2019 Dec; 9 (4):425-433 Epub 2019 Apr 04
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  32. Hilal T, Maguire A, Kosiorek HE, Rimsza LM, Rosenthal AC. Clinical features and cell of origin subtyping using gene expression profiling in HIV-negative patients with primary central nervous system lymphoma. Leuk Lymphoma 2019 Dec; 60 (14):3581-3583 Epub 2019 June 27
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  33. Hilal T. Hanging Up the Gloves. Oncologist. 2019 Oct; 24 (10):1403-1404 Epub 2019 May 23
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  34. Hilal T, Mudd J, DeLoughery TG. Hemostatic complications associated with ventricular assist devices. Res Pract Thromb Haemost. 2019 Oct; 3 (4):589-598 Epub 2019 June 09
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  35. Hilal T, Sonbol MB, Prasad V. Analysis of Control Arm Quality in Randomized Clinical Trials Leading to Anticancer Drug Approval by the US Food and Drug Administration. JAMA Oncol. 2019 Jun 1; 5 (6):887-892
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  36. Hilal T. I Don't Know. Am J Hosp Palliat Care. 2019 Apr; 36 (4):348-349 Epub 2018 Sept 19
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  37. Al-Husseini MJ, Saad AM, Jazieh KA, Elmatboly AM, Rachid A, Gad MM, Ruhban IA, Hilal T. Outcome disparities in colorectal cancer: a SEER-based comparative analysis of racial subgroups. Int J Colorectal Dis. 2019 Feb; 34(2):285-292. Epub 2018 Nov 15.
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  38. Scheckel CJ, Kosiorek HE, Butterfield R, Ho TH, Hilal T. Germ Cell Tumors with Malignant Somatic Transformation: A Mayo Clinic Experience. Oncol Res Treat. 2019; 42(3):95-100. Epub 2019 Feb 27.
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  39. Hilal T, Prasad V. Eliminating MRD - FDA approval of blinatumomab for B-ALL in complete remission. Nat Rev Clin Oncol. 2018 Dec; 15 (12):727-728
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  40. Hilal T, Patel BK. ASO Author Reflections: Role of Contrast-Enhanced Spectral Mammography in the Assessment of Residual Breast Cancer After Neoadjuvant Systemic Therapy. Ann Surg Oncol 2018 Dec; 25 (Suppl 3):652-653 Epub 2018 Oct 15
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  41. Hilal T, Covington M, Kosiorek HE, Zwart C, Ocal IT, Pockaj BA, Northfelt DW, Patel BK. Breast MRI phenotype and background parenchymal enhancement may predict tumor response to neoadjuvant endocrine therapy. Breast J. 2018 Nov; 24 (6):1010-1014 Epub 2018 July 31
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  42. Hilal T, Wang Z, Almader-Douglas D, Rosenthal A, Reeder CB, Jain T. Rituximab maintenance therapy for mantle cell lymphoma: A systematic review and meta-analysis. Am J Hematol. 2018 Oct; 93 (10):1220-1226 Epub 2018 Sept 03
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  43. Hilal T, Gea-Banacloche JC, Leis JF. Chronic lymphocytic leukemia and infection risk in the era of targeted therapies: Linking mechanisms with infections. Blood Rev. 2018 Sep; 32 (5):387-399 Epub 2018 Mar 16
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  44. Sonbol MB, Hilal T, Dueck AC, Rosenthal AC, Conley CR, Kosiorek HE, Ginos BF, Gano KM, Nichols CS, Leis JF, Johnston PB, Habermann TM, Northfelt DW, Bergsagel PL, Inwards DJ, Witzig TE, Ansell SM, Reeder CB. A phase 2 study of rituximab, cyclophosphamide, bortezomib and dexamethasone (R-CyBorD) in relapsed low grade and mantle cell lymphoma. Leuk Lymphoma. 2018 Sep; 59(9):2128-2134. Epub 2018 Jan 10.
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  45. Hilal T, Betcher JA, Leis JF. Economic Impact of Oral Therapies for Chronic Lymphocytic Leukemia-the Burden of Novelty. Curr Hematol Malig Rep. 2018 Aug; 13 (4):237-243
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  46. Hilal T, DiCaudo DJ, Connolly SM, Reeder CB. Necrobiotic xanthogranuloma: a 30-year single-center experience. Ann Hematol. 2018 Aug; 97 (8):1471-1479 Epub 2018 Mar 22
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  47. Sonbol MB, Firwana B, Hilal T, Wang Z, Almader-Douglas D, Joseph RW, Ho TH. Adjuvant Antiangiogenic Agents in Post-nephrectomy Renal Cell Carcinoma: A Systematic Review and Meta-analysis. Eur Urol Oncol. 2018 Jun; 1 (2):101-108 Epub 2018 Mar 15
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  48. Hilal T, Leis JF, Reeder CB. Rituximab Maintenance Therapy After First-Line Induction Chemoimmunotherapy for Follicular Lymphoma. JAMA Oncol 2018 Jun 1; 4 (6):859-860
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  49. Patel BK, Hilal T, Covington M, Zhang N, Kosiorek HE, Lobbes M, Northfelt DW, Pockaj BA. Contrast-Enhanced Spectral Mammography is Comparable to MRI in the Assessment of Residual Breast Cancer Following Neoadjuvant Systemic Therapy. Ann Surg Oncol. 2018 May; 25 (5):1350-1356 Epub 2018 Mar 07
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  50. Hilal T, Bansal P, Kelemen K, Slack J. Nivolumab-associated bone marrow necrosis. Ann Oncol 2018 Feb 1; 29 (2):513-514
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  51. Hilal T, Fauble V, Ketterling RP, Kelemen K. Myeloid neoplasm with eosinophilia associated with isolated extramedullary FIP1L1/PDGFRA rearrangement. Cancer Genet. 2018 Jan; 220:13-18 Epub 2017 Oct 23
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  52. Hilal T, Conley CR. B-cell acute lymphoblastic leukemia with +der(1)t(1;19) (p13;p13.1) arising in the setting of CALR exon 9 mutated essential thrombocythemia. Cancer Genet 2017 Dec; 218-219:81-83 Epub 2017 Oct 19
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  53. Hilal T, Nakazawa M, Hodskins J, Villano JL, Mathew A, Goel G, Wagner L, Arnold SM, DeSimone P, Anthony LB, Hosein PJ. Comprehensive genomic profiling in routine clinical practice leads to a low rate of benefit from genotype-directed therapy. BMC Cancer. 2017 Aug 30; 17 (1):602
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  54. Hilal T, Slone S, Peterson S, Bodine C, Gul Z. Cytomegalovirus reactivation is associated with a lower rate of early relapse in myeloid malignancies independent of in-vivo T cell depletion strategy. Leuk Res. 2017 Jun; 57:37-44 Epub 2017 Mar 01
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  55. Hilal T. Current understanding and approach to well differentiated lung neuroendocrine tumors: an update on classification and management. Ther Adv Med Oncol. 2017 Mar; 9 (3):189-199 Epub 2016 Nov 17
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  56. Hilal T. A cause to consider for chronic unresolving diarrhea. Gastroenterol Rep (Oxf). 2016 May; 4: (2)162-4.
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  57. Hilal T, Romond EH. ERBB2 (HER2) Testing in Breast Cancer. JAMA. 2016 Mar 22-29; 315: (12)1280-1.
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  58. Hilal T, Rudy DW. Radiation-induced breast cancer: the question of early breast cancer screening in Hodgkin's lymphoma survivors. Oxf Med Case Reports. 2016 Feb; 2016: (2)17-8.
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  59. Hilal T, Anthony LB, Sorrell VL. Unexpected Cardiac Masses. JAMA Oncol. 2015 Dec; 1: (9)1343-4.
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  60. Hilal T, Snapp WK. The perils of country life: human monocytic ehrlichiosis. Am J Med. 2015 Aug; 128 (8):831-3 Epub 2015 Apr 23
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  61. Hilal T. Bilateral upper lobe opacification. Med J Aust. 2015 Jun 15; 202: (11)586.
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  62. Hilal T . Autoimmune hepatitis associated with an abnormally low ceruloplasmin level Journal of Case Reports in Practice.2015 Apr;3:(2):35-37.
  63. Hilal T, Woods R. A tick-borne illness unmasking asymptomatic Brugada syndrome. Oxf Med Case Reports. 2015 Feb; 2015: (2)191-3.
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  64. Hilal T. Fatal cytomegalovirus disease after combination therapy with corticosteroids and rituximab for granulomatosis with polyangiitis. Case Rep Rheumatol. 2015; 2015:538137.
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  65. Hilal T. Diffuse unresolving pulmonary nodules in a patient with a history of cervical carcinoma. BMJ Case Rep. 2015; 2015:
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  66. Hilal T. Sudden cardiac arrest in a healthy young athlete. BMJ Case Rep. 2015; 2015:
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  67. Hensley P, Hilal T, Neltner J, Kumar B. Maintaining sharp focus on a grainy film: miliary pattern in an elderly woman with acute respiratory failure. BMJ Case Rep. 2015; 2015:
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  68. Hilal T, Gul Z. Exploring the possibilities: airspace disease in the postallogeneic haematopoietic stem cell transplant period. BMJ Case Rep. 2015; 2015:
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  69. Hilal T . Isolated neurocutaneous peripheral T cell lymphoma NOS International Journal of Case Reports and Images.2014 Dec 1;5:(12):859-63.
  70. Hilal T. Chronic rupture of the coronary sinus of Valsalva with pseudoaneurysm formation. Oxf Med Case Reports. 2014 Oct; 2014: (7)120-1.
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  71. Hilal T, Hurley P, McCormick M. Disseminated tuberculosis with tuberculous meningitis in an immunocompetent host. Oxf Med Case Reports. 2014 Oct; 2014: (7)125-8.
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  72. Hilal T . Advanced cutaneous Kaposi’s sarcoma: An uncommon AIDS-related manifestation in the era of antiretroviral therapy International Journal of Case Reports and Images.2014 Oct 1;5:(10):731-33.
  73. Hilal T, Morehead RS. Fulminant Wilson's Disease Managed with Plasmapheresis as a Bridge to Liver Transplant. Case Rep Med. 2014; 2014:672985.
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