搜索医生

Barry A. Borlaug, M.D.

  1. Cardiologist
预约门诊

出版物

  1. Melenovsky V, Hoskova E, Velebova K, Veleba J, Borlaug BA, Benes J, Kuda O, Cajka T, Segetova M, Thieme L, Kopecky J Jr, Kopecky J Sr, Pelikanova T, Haluzik M, Hill M, Kahleova H. Metformin Improves Glycemic Control and Postprandial Metabolism and Enhances Postprandial Glucagon-Like Peptide 1 Secretion in Patients With Type 2 Diabetes and Heart Failure: A Randomized, Double-Blind, Placebo-Controlled Trial. Clin Diabetes. 2025 Winter; 43 (1):23-32 Epub 2024 Sept 09
    View PubMed
  2. Doi S, Reddy YNV, Jensen MD, Smith JR, Borlaug BA. Dapagliflozin and ventilatory control during exercise in heart failure with preserved ejection fraction: the CAMEO-DAPA trial. Eur Heart J. 2025 Apr 22; 46 (16):1554-1556
    View PubMed
  3. Reddy YNV, Tada A, Obokata M, Carter RE, Kaye DM, Handoko ML, Andersen MJ, Sharma K, Tedford RJ, Redfield MM, Borlaug BA. Evidence-Based Application of Natriuretic Peptides in the Evaluation of Chronic Heart Failure With Preserved Ejection Fraction in the Ambulatory Outpatient Setting. Circulation. 2025 Apr 8; 151 (14):976-989 Epub 2025 Jan 22
    View PubMed
  4. Naser JA, Rahme SJ, Ibrahim H, Scott CG, Michelena HI, Borlaug BA, Kennedy AM, Eleid MF, Nkomo VT, Pellikka PA, Enriquez-Sarano M, Pislaru SV. Role of Quantitative Assessment of Atrial Functional Mitral Regurgitation. J Am Soc Echocardiogr. 2025 Apr; 38 (4):353-355 Epub 2024 Dec 15
    View PubMed
  5. Sorimachi H, Obokata M, Omote K, Reddy YNV, Burkhoff D, Shah SJ, Borlaug BA. Racial Differences of Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction. J Card Fail. 2025 Apr; 31 (4):624-634 Epub 2024 Aug 23
    View PubMed
  6. Egbe AC, Reddy YNV, Miranda WR, Jain CC, Connolly HM, Borlaug BA. Hemodynamics of Exercise-Induced Hypertension and Relationship to Outcomes in Adults With Coarctation of the Aorta. Circ Heart Fail. 2025 Apr; 18 (4):e012459 Epub 2025 Mar 05
    View PubMed
  7. Younis A, Reddy YNV, Miranda WR, Abdelhalim AT, Borlaug BA, Connolly HM, Egbe AC. Temporal changes in prevalence and severity of pulmonary hypertension, and relationship to outcomes in coarctation of aorta. Int J Cardiol Heart Vasc. 2025 Apr; 57:101626 Epub 2025 Feb 07
    View PubMed
  8. Naser JA, Ibrahim H, Andi K, Scott CG, Pellikka PA, Kennedy AM, Connolly HM, Nkomo VT, Enriquez-Sarano M, Pislaru SV, Warnes CA, Jain CC, Borlaug BA, Egbe AC. Prevalence, aetiology, and outcomes of native pulmonary regurgitation in the general adult population. Eur Heart J Cardiovasc Imaging. 2025 Mar 27; 26 (4):695-702
    View PubMed
  9. Packer M, Zile MR, Kramer CM, Murakami M, Ou Y, Borlaug BA, SUMMIT Trial Study Group. Interplay of Chronic Kidney Disease and the Effects of Tirzepatide in Patients With Heart Failure, Preserved Ejection Fraction, and Obesity: The SUMMIT Trial. J Am Coll Cardiol. 2025 Mar 24 [Epub ahead of print]
    View PubMed
  10. Pandey A, Lewis GD, Borlaug BA, Shah SJ, Sauer AJ, Litwin S, Sharma K, Jorkasky DK, Tarka EA, Khan SM, Kitzman DW. Novel Controlled Metabolic Accelerator for Obesity-Related HFpEF: The HuMAIN-HFpEF Randomized Clinical Trial. JAMA Cardiol. 2025 Mar 12 [Epub ahead of print]
    View PubMed
  11. Fazzini L, Padkins MR, Berg-Hansen K, Gori M, Kane GC, Hillerson DB, Tavazzi G, Reddy YNV, Jae OK, Borlaug B, Jentzer JC. Left ventricular-arterial coupling and mortality in the cardiac intensive care unit. Eur Heart J Acute Cardiovasc Care. 2025 Mar 12 [Epub ahead of print]
    View PubMed
  12. Zile MR, Borlaug BA, Kramer CM, Baum SJ, Litwin SE, Menon V, Ou Y, Weerakkody GJ, Hurt KC, Kanu C, Murakami M, Packer M, SUMMIT Trial Study Group. Effects of Tirzepatide on the Clinical Trajectory of Patients With Heart Failure, Preserved Ejection Fraction, and Obesity. Circulation. 2025 Mar 11; 151 (10):656-668 Epub 2024 Nov 18
    View PubMed
  13. Farha S, Asosingh K, Hassoun PM, Barnard J, Comhair S, Reichard A, Wanner N, Radeva M, Aldred MA, Beck GJ, Berman-Rosenzweig E, Borlaug BA, Finet JE, Frantz RP, Grunig G, Hemnes AR, Hill N, Horn EM, Jellis C, Leopold JA, Mehra R, Park MM, Rischard FP, Tang WHW, Erzurum SC, PVDOMICS Study Group. Alterations in Mitochondrial Function in Pulmonary Vascular Diseases. Antioxid Redox Signal. 2025 Mar; 42 (7-9):361-377 Epub 2024 Dec 10
    View PubMed
  14. Shah SJ, Bonderman D, Borlaug BA, Cleland JGF, Lack G, Lu W, Voors AA, Zannad F, Gladwin MT. Macitentan for Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Pulmonary Vascular Disease: Results of the SERENADE Randomized Clinical Trial and Open-Label Extension Study. Circ Heart Fail. 2025 Mar; 18 (3):e011381 Epub 2025 Mar 11
    View PubMed
  15. Cao JJL, Miranda WR, Borlaug BA, Reddy YNV. Pseudo-Severe Mitral Stenosis From Obesity-Related HFpEF and Atrial Myopathy. Circ Heart Fail. 2025 Mar; 18 (3):e012703 Epub 2025 Jan 28
    View PubMed
  16. Davies MJ, van der Meer P, Verma S, Patel S, Chinnakondepalli KM, Borlaug BA, Butler J, Kitzman DW, Shah SJ, Harring S, Salsali A, Rasmussen S, von Lewinski D, Abhayaratna W, Petrie MC, Kosiborod MN, STEP-HFpEF Trials Committees and Investigators. Semaglutide in obesity-related heart failure with preserved ejection fraction and type 2 diabetes across baseline HbA(1c) levels (STEP-HFpEF DM): a prespecified analysis of heart failure and metabolic outcomes from a randomised, placebo-controlled trial. Lancet Diabetes Endocrinol. 2025 Mar; 13 (3):196-209 Epub 2025 Jan 20
    View PubMed
  17. Davies MJ, van der Meer P, Verma S, Patel S, Chinnakondepalli KM, Borlaug BA, Butler J, Kitzman DW, Shah SJ, Harring S, Salsali A, Rasmussen S, von Lewinski D, Abhayaratna W, Petrie MC, Kosiborod MN. Semaglutide in obesity-related heart failure with preserved ejection fraction and type 2 diabetes across baseline hba levels (step-hfpef dm): a prespecified analysis of heart failure and metabolic outcomes from a randomised, placebo-controlled trial 1c. Lancet Diabetes & Endocrinology. 2025 Mar; 13 (3):196-209
  18. Kramer CM, Borlaug BA, Zile MR, Ruff D, DiMaria JM, Menon V, Ou Y, Zarante AM, Hurt KC, Murakami M, Packer M, SUMMIT Trial Study Group. Tirzepatide Reduces LV Mass and Paracardiac Adipose Tissue in Obesity-Related Heart Failure: SUMMIT CMR Substudy. J Am Coll Cardiol. 2025 Feb 25; 85 (7):699-706 Epub 2024 Nov 18
    View PubMed
  19. Opp DN, Jain CC, Egbe AC, Borlaug BA, Reddy YV, Connolly HM, Lara-Breitinger KM, Cordina R, Miranda WR. Fontan haemodynamics in adults with obesity compared with overweight and normal body mass index: a retrospective invasive exercise study. Eur J Prev Cardiol. 2025 Feb 18; 32 (3):221-230
    View PubMed
  20. Fioretti F, Nair AP, Anker SD, Borlaug BA, Kereiakes DJ, Lindenfeld J, Stone GW, Butler J. Therapeutic left-to-right shunting in heart failure. Eur Heart J. 2025 Feb 13 [Epub ahead of print]
    View PubMed
  21. Salah HM, Fudim M, Borlaug BA, Litwin SE, Stark M, Shah SJ, Burkhoff D. Changes in Stressed Blood Volume With Endovascular Ablation of the Right Greater Splanchnic Nerve in Heart Failure With Preserved Ejection Fraction: The REBALANCE-HF Trial. J Card Fail. 2025 Feb 13 [Epub ahead of print]
    View PubMed
  22. Zalawadiya SK, Kiernan M, Borlaug BA, Stevenson LW, Desai AS, Bennett M, Mullens W, Hiivala NJ, Owens MM, Klein L. Changes in Seated Pulmonary Artery Pressure in Response to Titration of Heart Failure Medications During Ambulatory Monitoring. J Card Fail. 2025 Feb 11 [Epub ahead of print]
    View PubMed
  23. Molinsky RL, Shah A, Yuzefpolskaya M, Yu B, Misialek JR, Bohn B, Vock D, MacLehose R, Borlaug BA, Colombo PC, Ndumele CE, Ishigami J, Matsushita K, Lutsey PL, Demmer RT. Infection-Related Hospitalization and Incident Heart Failure: The Atherosclerosis Risk in Communities Study. J Am Heart Assoc. 2025 Feb 4; 14 (3):e033877 Epub 2025 Jan 30
    View PubMed
  24. Borlaug BA, Zile MR, Kramer CM, Baum SJ, Hurt K, Litwin SE, Murakami M, Ou Y, Upadhyay N, Packer M. Effects of tirzepatide on circulatory overload and end-organ damage in heart failure with preserved ejection fraction and obesity: a secondary analysis of the SUMMIT trial. Nat Med. 2025 Feb; 31 (2):544-551 Epub 2024 Nov 17
    View PubMed
  25. Egbe AC, Ali AE, Miranda WR, Connolly HM, Borlaug BA. Aerobic Capacity of Adults With Fontan Palliation: Disease-Specific Reference Values and Relationship to Outcomes. Circ Heart Fail. 2025 Feb; 18 (2):e011981 Epub 2024 Dec 09
    View PubMed
  26. Naser JA, Harada T, Reddy YN, Pislaru SV, Michelena HI, Scott CG, Kennedy AM, Pellikka PA, Nkomo VT, Eleid MF, Borlaug BA. Prevalence of HFpEF in Isolated Severe Secondary Tricuspid Regurgitation. JAMA Cardiol 2025 Feb 1; 10 (2):182-187
    View PubMed
  27. Fayyaz AU, Eltony M, Prokop LJ, Koepp KE, Borlaug BA, Dasari S, Bois MC, Margulies KB, Maleszewski JJ, Wang Y, Redfield MM. Pathophysiological insights into HFpEF from studies of human cardiac tissue. Nat Rev Cardiol. 2025 Feb; 22 (2):90-104 Epub 2024 Aug 28
    View PubMed
  28. Monzo L, Jarolim P, Borlaug BA, Benes J, Jurcova I, Jenca D, Kroupova K, Wohlfahrt P, Kotrc M, Melenovsky V. Growth Differentiation Factor-15 Is Associated With Congestion-Related Anorexia and Weight Loss in Advanced Heart Failure. JACC Heart Fail. 2025 Feb; 13 (2):315-329 Epub 2025 Jan 08
    View PubMed
  29. Packer M, Zile MR, Kramer CM, Baum SJ, Litwin SE, Menon V, Ge J, Weerakkody GJ, Ou Y, Bunck MC, Hurt KC, Murakami M, Borlaug BA, SUMMIT Trial Study Group. Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity. N Engl J Med. 2025 Jan 30; 392 (5):427-437 Epub 2024 Nov 16
    View PubMed
  30. Hortegal RA, Jain CC, Reddy YNV, Borlaug BA, Egbe AC, Miranda WR. Single-leg supine cycling: An alternative for patients requiring exercise catheterization and femoral access. Eur J Heart Fail. 2025 Jan 17 [Epub ahead of print]
    View PubMed
  31. Egbe AC, Reddy YNV, Miranda WR, Jain CC, Anderson JH, Connolly HM, Borlaug BA. Clinical features, hemodynamics, and outcomes of pulmonary hypertension in adults with coarctation of aorta. Int J Cardiol. 2025 Jan 1; 418:132634 Epub 2024 Oct 11
    View PubMed
  32. Doi S, Borlaug BA. Pericardiotomy as a novel treatment for heart failure with preserved ejection fraction. Heart Fail Rev. 2025 Jan; 30 (1):137-142 Epub 2024 Oct 08
    View PubMed
  33. Ambrosy AP, Sauer AJ, Patel S, Windsor SL, Borlaug BA, Husain M, Inzucchi SE, Kitzman DW, McGuire DK, Shah SJ, Sharma K, Umpierrez G, Kosiborod MN. Baseline kidney function and the effects of dapagliflozin on health status in heart failure in DEFINE-HF and PRESERVED-HF. ESC Heart Fail. 2024 Dec 24 [Epub ahead of print]
    View PubMed
  34. Egbe AC, Reddy YNV, Ali AE, Younis A, Borlaug BA. Clinical features, haemodynamics, and outcomes of heart failure with preserved ejection fraction in coarctation of aorta. Eur J Heart Fail. 2024 Dec; 26 (12):2595-2603 Epub 2024 July 16
    View PubMed
  35. Hammer SM, Bruhn EJ, Bissen TG, Cifci G, Borlaug BA, Olson TP, Smith JR. Impaired Vastus Lateralis Blood Flow During Cycling Exercise in Heart Failure With Preserved Ejection Fraction. J Card Fail. 2024 Dec; 30 (12):1637-1640 Epub 2024 May 20
    View PubMed
  36. Naser JA, Harada T, Tada A, Doi S, Tsaban G, Pislaru SV, Nkomo VT, Scott CG, Kennedy AM, Eleid MF, Reddy YNV, Lin G, Pellikka PA, Borlaug BA. Prevalence, Incidence, and Outcomes of Diastolic Dysfunction in Isolated Tricuspid Regurgitation: Perhaps Not Really "Isolated"? JACC Cardiovasc Imaging. 2024 Dec; 17 (12):1411-1424 Epub 2024 July 24
    View PubMed
  37. Akhiyat N, Anand V, Kumar V, Ryu A, Gibbons R, Borlaug BA, Chandrasekaran K, Abou Ezzeddine O, Anavekar N. The myocardial function index (MFI): An integrated measure of cardiac function in AL-cardiomyopathy. Int J Cardiol Heart Vasc. 2024 Dec; 55:101525 Epub 2024 Oct 15
    View PubMed
  38. Litwin SE, Komtebedde J, Borlaug BA, Kaye DM, Hasenfubeta G, Kawash R, Hoendermis E, Hummel SL, Cikes M, Gustafsson F, Chung ES, Mohan RC, Sverdlov AL, Swarup V, Winkler S, Hayward CS, Bergmann MW, Bugger H, McKenzie S, Nair A, Rieth A, Burkhoff D, Cutlip DE, Solomon SD, van Veldhuisen DJ, Leon MB, Shah SJ. Long term safety and outcomes after atrial shunting for heart failure with preserved or mildly reduced ejection fraction: 5-year and 3-year follow-up in the REDUCE LAP-HF I and II trials. Am Heart J. 2024 Dec; 278:106-116 Epub 2024 Sept 03
    View PubMed
  39. Jain CC, Egbe AC, Allison TG, van de Bruaene A, Borlaug BA, Connolly HM, Burchill LJ, Miranda WR. Functional Capacity Assessment in Adults After Fontan Palliation: A Cardiopulmonary Exercise Test-Invasive Exercise Hemodynamics Correlation Study. Am J Cardiol. 2024 Dec 1; 232:82-88 Epub 2024 Sept 06
    View PubMed
  40. Fudim M, Borlaug BA, Mohan RC, Price MJ, Fail P, Goyal P, Hummel SL, Zirakashvili T, Shaburishvili T, Patel RB, Reddy VY, Nielsen CD, Chetcuti SJ, Sukul D, Gulati R, Kim L, Benzuly K, Mitter SS, Klein L, Uriel N, Augostini RS, Blair JE, Rocha-Singh K, Burkhoff D, Patel MR, Somo SI, Litwin SE, Shah SJ. Endovascular Ablation of the Greater Splanchnic Nerve in Heart Failure With Preserved Ejection Fraction: The REBALANCE-HF Randomized Clinical Trial. JAMA Cardiol. 2024 Dec 1; 9 (12):1143-1153
    View PubMed
  41. Reddy YNV, Frantz RP, Hassoun PM, Hemnes AR, Horn E, Leopold JA, Rischard F, Rosenzweig EB, Hill NS, Erzurum SC, Beck GJ, Finet JE, Jellis CL, Mathai SC, Tang WHW, Borlaug BA. Clinical Implications of Pretest Probability of HFpEF on Outcomes in Precapillary Pulmonary Hypertension. J Am Coll Cardiol. 2024 Nov 26; 84 (22):2196-2210 Epub 2024 Oct 23
    View PubMed
  42. Sharif SM, Smith JR, Borlaug BA, Olson TP. Association between locomotor muscle quality and cardiac function during exercise in heart failure with preserved ejection fraction. Eur J Heart Fail. 2024 Nov 19 [Epub ahead of print]
    View PubMed
  43. Gopalasingam N, Berg-Hansen K, Christensen KH, Ladefoged BT, Poulsen SH, Andersen MJ, Borlaug BA, Nielsen R, Moller N, Wiggers H. Randomized Crossover Trial of 2-Week Ketone Ester Treatment in Patients With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction. Circulation. 2024 Nov 12; 150 (20):1570-1583 Epub 2024 Aug 20
    View PubMed
  44. Reddy YNV, Dubrock H, Hassoun PM, Hemnes A, Horn E, Leopold JA, Rischard F, Rosenzweig EB, Hill NS, Erzurum SC, Beck GJ, Mathai SC, Mukherjee M, Tang WHW, Borlaug BA, Frantz RP, and the PVDOMICS Study Group. Non-invasive prediction of pulmonary vascular disease-related exercise intolerance and survival in non-group 1 pulmonary hypertension. Eur J Heart Fail. 2024 Nov; 26 (11):2323-2336 Epub 2024 July 26
    View PubMed
  45. Selvaraj S, Patel S, Sauer AJ, McGarrah RW, Jones P, Kwee LC, Windsor SL, Ilkayeva O, Muehlbauer MJ, Newgard CB, Borlaug BA, Kitzman DW, Shah SJ, Margulies KB, Husain M, Inzucchi SE, McGuire DK, Lanfear DE, Javaheri A, Umpierrez G, Mentz RJ, Sharma K, Kosiborod MN, Shah SH. Metabolic Effects of the SGLT2 Inhibitor Dapagliflozin in Heart Failure Across the Spectrum of Ejection Fraction. Circ Heart Fail. 2024 Nov; 17 (11):e011980 Epub 2024 Oct 18
    View PubMed
  46. Egbe AC, Borlaug BA, Miranda WR, Karnakoti S, Ali AE, Younis A, Connolly HM. Sex Differences in Outcomes of Adults with Repaired Coarctation of Aorta and Concomitant Aortic Valve Disease. CJC Open. 2024 Nov; 6 (11):1386-1394 Epub 2024 Aug 22
    View PubMed
  47. Reddy YNV, Miranda WR, Jain CC, Borlaug BA, Egbe AC. Haemodynamic contributors to pulmonary hypertension across the spectrum of adult congenital heart disease. Eur J Heart Fail. 2024 Nov; 26 (11):2356-2366 Epub 2024 July 02
    View PubMed
  48. Harada T, Tada A, Borlaug BA. Imaging and mechanisms of heart failure with preserved ejection fraction: a state-of-the-art review. Eur Heart J Cardiovasc Imaging. 2024 Oct 30; 25 (11):1475-1490
    View PubMed
  49. Verma S, Petrie MC, Borlaug BA, Butler J, Davies MJ, Kitzman DW, Shah SJ, Ronnback C, Abildstrom SZ, Liisberg K, Wolf D, von Lewinski D, Lelonek M, Melenovsky V, Senni M, Kosiborod MN, STEP-HFpEF Trial Committees and Investigators. Inflammation in Obesity-Related HFpEF: The STEP-HFpEF Program. J Am Coll Cardiol. 2024 Oct 22; 84 (17):1646-1662 Epub 2024 Aug 30
    View PubMed
  50. Verma S, Butler J, Borlaug BA, Davies MJ, Kitzman DW, Petrie MC, Shah SJ, Jensen TJ, Rasmussen S, Ronnback C, Merkely B, O'Keefe E, Kosiborod MN, STEP-HFpEF and STEP-HFpEF DM Investigators. Atrial Fibrillation and Semaglutide Effects in Obesity-Related Heart Failure With Preserved Ejection Fraction: STEP-HFpEF Program. J Am Coll Cardiol. 2024 Oct 22; 84 (17):1603-1614 Epub 2024 Aug 30
    View PubMed
  51. Solomon SD, Ostrominski JW, Wang X, Shah SJ, Borlaug BA, Butler J, Davies MJ, Kitzman DW, Verma S, Abildstrom SZ, Nygaard Einfeldt M, Rasmussen S, Abhayaratna WP, Ahmed FZ, Ben-Gal T, Chopra V, Ito H, Merkely B, Nunez J, Senni M, van der Meer P, Wolf D, Petrie MC, Kosiborod MN, STEP-HFpEF Trial Committees and Investigators. Effect of Semaglutide on Cardiac Structure and Function in Patients With Obesity-Related Heart Failure. J Am Coll Cardiol. 2024 Oct 22; 84 (17):1587-1602 Epub 2024 Aug 30
    View PubMed
  52. Reddy YNV, Melenovsky V, Asokan AK, Haluzik M, Carter RE, Nair S, Jensen MD, Borlaug BA. Dapagliflozin, peptide YY, and weight loss in heart failure with preserved ejection fraction. Eur Heart J. 2024 Oct 05; 45(37):3889-3891.
    View PubMed
  53. Tada A, Burkhoff D, Naser JA, Harada T, Pourmussa B, Reddy YNV, Jensen MD, Carter RE, Demmer RT, Testani JM, Chirinos JA, Borlaug BA. Dapagliflozin Enhances Arterial and Venous Compliance During Exercise in Heart Failure With Preserved Ejection Fraction: Insights From the CAMEO-DAPA Trial. Circulation. 2024 Sep 24; 150 (13):997-1009 Epub 2024 Aug 05
    View PubMed
  54. Ng ACT, Dong X, Koepp KE, Obokata M, Sorimachi H, Galloway G, Araoz P, Delgado V, Bax JJ, Borlaug BA. Sexual dimorphism in the relationships between intramyocardial fat, myocardial fibrosis, and exercise intolerance in heart failure with preserved ejection fraction. Eur J Heart Fail. 2024 Sep 24 Epub 2024 Sept 24
    View PubMed
  55. Tada A, Burkhoff D, Naser JA, Harada T, Pourmussa B, Reddy YNV, Jensen MD, Carter RE, Demmer RT, Testani JM, Chirinos JA, Borlaug BA. Dapagliflozin enhances arterial and venous compliance during exercise in heart failure with preserved ejection fraction: insights from the cameo-dapa trial. Circulation. 2024 Sep 24; 150 (13):997-1009
  56. Shah SJ, Sharma K, Borlaug BA, Butler J, Davies M, Kitzman DW, Petrie MC, Verma S, Patel S, Chinnakondepalli KM, Einfeldt MN, Jensen TJ, Rasmussen S, Asleh R, Ben-Gal T, Kosiborod MN. Semaglutide and diuretic use in obesity-related heart failure with preserved ejection fraction: a pooled analysis of the STEP-HFpEF and STEP-HFpEF-DM trials. Eur Heart J. 2024 Sep 14; 45 (35):3254-3269
    View PubMed
  57. Kosiborod MN, Deanfield J, Pratley R, Borlaug BA, Butler J, Davies MJ, Emerson SS, Kahn SE, Kitzman DW, Lingvay I, Mahaffey KW, Petrie MC, Plutzky J, Rasmussen S, Ronnback C, Shah SJ, Verma S, Weeke PE, Lincoff AM, SELECT, FLOW, STEP-HFpEF, and STEP-HFpEF DM Trial Committees and Investigators. Semaglutide versus placebo in patients with heart failure and mildly reduced or preserved ejection fraction: a pooled analysis of the SELECT, FLOW, STEP-HFpEF, and STEP-HFpEF DM randomised trials. Lancet. 2024 Sep 7; 404 (10456):949-961 Epub 2024 Aug 30
    View PubMed
  58. Kitzman DW, Lewis GD, Pandey A, Borlaug BA, Sauer AJ, Litwin SE, Sharma K, Jorkasky DK, Khan S, Shah SJ. A novel controlled metabolic accelerator for the treatment of obesity-related heart failure with preserved ejection fraction: Rationale and design of the Phase 2a HuMAIN trial. Eur J Heart Fail. 2024 Sep; 26 (9):2013-2024 Epub 2024 June 26
    View PubMed
  59. Cassianni C, Huntley GD, Castrichini M, Akerman AP, Porumb M, Scott CG, Davison HN, Hawkes W, Woodward G, Borlaug B, Upton R, Pellikka PA. Automated Echocardiographic Detection of Heart Failure With Preserved Ejection Fraction Using Artificial Intelligence Is Associated With Cardiac Mortality and Heart Failure Hospitalization. J Am Soc Echocardiogr 2024 Sep; 37 (9):914-916 Epub 2024 July 02
    View PubMed
  60. Reddy YNV, Carter RE, Sorimachi H, Omar M, Popovic D, Alogna A, Jensen MD, Borlaug BA. Dapagliflozin and Right Ventricular-Pulmonary Vascular Interaction in Heart Failure With Preserved Ejection Fraction: A Secondary Analysis of a Randomized Clinical Trial. JAMA Cardiol 2024 Sep 1; 9 (9):843-851
    View PubMed
  61. Monzo L, Kovar J, Borlaug BA, Benes J, Kotrc M, Kroupova K, Jabor A, Franekova J, Melenovsky V. Circulating beta-hydroxybutyrate levels in advanced heart failure with reduced ejection fraction: Determinants and prognostic impact. Eur J Heart Fail. 2024 Sep; 26 (9):1931-1940 Epub 2024 June 10
    View PubMed
  62. Verma S, Butler J, Borlaug BA, Davies M, Kitzman DW, Shah SJ, Petrie MC, Barros E, Ronnback C, Vestergaard LS, Schou M, Ezekowitz JA, Sharma K, Patel S, Chinnakondepalli KM, Kosiborod MN, STEP-HFpEF Trial Committees and Investigators. Efficacy of Semaglutide by Sex in Obesity-Related Heart Failure With Preserved Ejection Fraction: STEP-HFpEF Trials. J Am Coll Cardiol. 2024 Aug 27; 84 (9):773-785 Epub 2024 June 23
    View PubMed
  63. Borlaug BA, Kindel TL. Obesity and Heart Failure: A New Era Begins. J Card Fail 2024 Aug; 30 (8):1063-1064 Epub 2024 Mar 04
    View PubMed
  64. Gustafsson F, Petrie MC, Komtebedde J, Swarup V, Winkler S, Hasenfuss G, Borlaug BA, Mohan RC, Flaherty JD, Sverdlov AL, Fail PS, Chung ES, Lurz P, Lilly S, Kaye DM, Cleland JGF, Cikes M, Leon MB, Cutlip DE, van Veldhuisen DJ, Solomon SD, Shah SJ. 2-Year Outcomes of an Atrial Shunt Device in HFpEF/HFmrEF: Results From REDUCE LAP-HF II. JACC Heart Fail. 2024 Aug; 12 (8):1425-1438 Epub 2024 June 26
    View PubMed
  65. Reddy YNV, Carter RE, Sundaram V, Kaye DM, Handoko ML, Tedford RJ, Andersen MJ, Sharma K, Obokata M, Verbrugge FH, Borlaug BA. An evidence-based screening tool for heart failure with preserved ejection fraction: the HFpEF-ABA score. Nat Med. 2024 Aug; 30 (8):2258-2264 Epub 2024 July 12
    View PubMed
  66. Khan MS, Talha KM, Maqsood MH, Rymer JA, Borlaug BA, Docherty KF, Pandey A, Kahles F, Cikes M, Lam CSP, Ducharme A, Voors AA, Hernandez AF, Lincoff AM, Petrie MC, Ridker PM, Fudim M. Interleukin-6 and Cardiovascular Events in Healthy Adults: MESA. JACC Adv. 2024 Aug; 3 (8):101063 Epub 2024 July 09
    View PubMed
  67. Schou M, Petrie MC, Borlaug BA, Butler J, Davies MJ, Kitzman DW, Shah SJ, Verma S, Patel S, Chinnakondepalli KM, Harring S, Abildstrom SZ, Liisberg K, Kosiborod MN, STEP-HFpEF Trial Committees and Investigators. Semaglutide and NYHA Functional Class in Obesity-Related Heart Failure With Preserved Ejection Fraction: The STEP-HFpEF Program. J Am Coll Cardiol. 2024 Jul 16; 84 (3):247-257 Epub 2024 June 23
    View PubMed
  68. Hahn RT, Lindenfeld J, Bohm M, Edelmann F, Lund LH, Lurz P, Metra M, Tedford RJ, Butler J, Borlaug BA. Tricuspid Regurgitation in Patients With Heart Failure and Preserved Ejection Fraction: JACC State-of-the-Art Review. J Am Coll Cardiol. 2024 Jul 9; 84 (2):195-212
    View PubMed
  69. Petrie MC, Borlaug BA, Butler J, Davies MJ, Kitzman DW, Shah SJ, Verma S, Jensen TJ, Einfeldt MN, Liisberg K, Perna E, Sharma K, Ezekowitz JA, Fu M, Melenovsky V, Ito H, Lelonek M, Kosiborod MN, STEP-HFpEF Trial Committees and Investigators. Semaglutide and NT-proBNP in Obesity-Related HFpEF: Insights From the STEP-HFpEF Program. J Am Coll Cardiol. 2024 Jul 2; 84 (1):27-40 Epub 2024 May 13
    View PubMed
  70. Fudim M, Litwin SE, Borlaug BA, Mohan RC, Price MJ, Fail P, Zirakashvili T, Shaburishvili T, Goyal P, Hummel SL, Patel RB, Reddy VY, Burkhoff D, Patel MR, Somo SI, Shah SJ. Endovascular Ablation of the Right Greater Splanchnic Nerve in Heart Failure With Preserved Ejection Fraction: Rationale, Design and Lead-in Phase Results of the REBALANCE-HF Trial. J Card Fail. 2024 Jul; 30 (7):877-889 Epub 2024 Jan 09
    View PubMed
  71. Tada A, Doi S, Harada T, Ibe T, Naser JA, Amdahl M, Reddy YNV, Borlaug BA. Autoimmune Disorders in Heart Failure With Preserved Ejection Fraction. JACC Heart Fail. 2024 Jul; 12 (7):1257-1269 Epub 2024 May 29
    View PubMed
  72. Borlaug BA, Larive B, Frantz RP, Hassoun P, Hemnes A, Horn E, Leopold J, Rischard F, Berman-Rosenzweig E, Beck G, Erzurum S, Farha S, Finet JE, Highland KB, Jacob M, Jellis C, Mehra R, Renapurkar R, Singh H, Tang WHW, Vanderpool R, Wilcox J, Yu S, Hill N. Pulmonary hypertension across the spectrum of left heart and lung disease. Eur J Heart Fail. 2024 Jul; 26 (7):1642-1651 Epub 2024 June 04
    View PubMed
  73. Harada T, Naser JA, Tada A, Doi S, Ibe T, Pislaru SV, Eleid MF, Sorimachi H, Obokata M, Reddy YNV, Borlaug BA. Cardiac function, haemodynamics, and valve competence with exercise in patients with heart failure with preserved ejection fraction and mild to moderate secondary mitral regurgitation. Eur J Heart Fail. 2024 Jul; 26 (7):1616-1627 Epub 2024 June 04
    View PubMed
  74. Rajagopalan N, Borlaug BA, Bailey AL, Eckman PM, Guglin M, Hall S, Montgomery M, Ramani G, Khazanie P. Practical Guidance for Hemodynamic Assessment by Right Heart Catheterization in Management of Heart Failure. JACC Heart Fail. 2024 Jul; 12 (7):1141-1156
    View PubMed
  75. Naser JA, Tada A, Harada T, Reddy YNV, Carter RE, Testani JM, Jensen MD, Borlaug BA. Effects of Dapagliflozin on Body Composition and Its Relation to Hemodynamics in Heart Failure With Preserved Ejection Fraction. Circulation 2024 Jun 18; 149 (25):2026-2028 Epub 2024 June 17
    View PubMed
  76. Patel RB, Silvestry FE, Komtebedde J, Solomon SD, Hasenfuss G, Litwin SE, Borlaug BA, Price MJ, Kawash R, Hummel SL, Cutlip DE, Leon MB, van Veldhuisen DJ, Rieth AJ, McKenzie S, Bugger H, Mazurek JA, Kapadia SR, Vanderheyden M, Ky B, Shah SJ. Atrial Shunt Device Effects on Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction: The REDUCE LAP-HF II Randomized Clinical Trial. JAMA Cardiol. 2024 Jun 1; 9 (6):507-522
    View PubMed
  77. Selvaraj S, Patel S, Sauer AJ, McGarrah RW, Jones P, Kwee LC, Windsor SL, Ilkayeva O, Muehlbauer MJ, Newgard CB, Borlaug BA, Kitzman DW, Shah SJ, Shah SH, Kosiborod MN, PRESERVED-HF Investigators. Targeted Metabolomic Profiling of Dapagliflozin in Heart Failure With Preserved Ejection Fraction: The PRESERVED-HF Trial. JACC Heart Fail. 2024 Jun; 12 (6):999-1011 Epub 2024 Apr 17
    View PubMed
  78. Henry JA, Abdesselam I, Deal O, Lewis AJ, Rayner J, Bernard M, Dutour A, Gaborit B, Kober F, Soghomonian A, Sgromo B, Byrne J, Bege T, Borlaug BA, Neubauer S, Rider OJ. The effect of bariatric surgery type on cardiac reverse remodelling. Int J Obes (Lond). 2024 Jun; 48 (6):808-814 Epub 2024 Jan 31
    View PubMed
  79. Reddy YNV, Noseworthy P, Borlaug BA, Albert NM. Screening for Unrecognized HFpEF in Atrial Fibrillation and for Unrecognized Atrial Fibrillation in HFpEF. JACC Heart Fail. 2024 Jun; 12 (6):990-998
    View PubMed
  80. Berg-Hansen K, Gopalasingam N, Christensen KH, Ladefoged B, Andersen MJ, Poulsen SH, Borlaug BA, Nielsen R, Moller N, Wiggers H. Cardiovascular Effects of Oral Ketone Ester Treatment in Patients With Heart Failure With Reduced Ejection Fraction: A Randomized, Controlled, Double-Blind Trial. Circulation. 2024 May 7; 149 (19):1474-1489 Epub 2024 Mar 27
    View PubMed
  81. Butler J, Shah SJ, Petrie MC, Borlaug BA, Abildstrom SZ, Davies MJ, Hovingh GK, Kitzman DW, Moller DV, Verma S, Einfeldt MN, Lindegaard ML, Rasmussen S, Abhayaratna W, Ahmed FZ, Ben-Gal T, Chopra V, Ezekowitz JA, Fu M, Ito H, Lelonek M, Melenovsky V, Merkely B, Nunez J, Perna E, Schou M, Senni M, Sharma K, van der Meer P, Von Lewinski D, Wolf D, Kosiborod MN, STEP-HFpEF Trial Committees and Investigators. Semaglutide versus placebo in people with obesity-related heart failure with preserved ejection fraction: a pooled analysis of the STEP-HFpEF and STEP-HFpEF DM randomised trials. Lancet. 2024 Apr 27; 403 (10437):1635-1648 Epub 2024 Apr 07
    View PubMed
  82. Naser JA, Alexandrino FB, Harada T, Michelena HI, Borlaug BA, Eleid MF, Lin G, Scott C, Kennedy AM, Pellikka PA, Nkomo VT, Pislaru SV. The Natural History of Atrial Functional Mitral Regurgitation. J Am Coll Cardiol. 2024 Apr 23; 83 (16):1495-1507 Epub 2024 Mar 25
    View PubMed
  83. Kosiborod MN, Petrie MC, Borlaug BA, Butler J, Davies MJ, Hovingh GK, Kitzman DW, Moller DV, Treppendahl MB, Verma S, Jensen TJ, Liisberg K, Lindegaard ML, Abhayaratna W, Ahmed FZ, Ben-Gal T, Chopra V, Ezekowitz JA, Fu M, Ito H, Lelonek M, Melenovsky V, Merkely B, Nunez J, Perna E, Schou M, Senni M, Sharma K, van der Meer P, Von Lewinski D, Wolf D, Shah SJ, STEP-HFpEF DM Trial Committees and Investigators. Semaglutide in Patients with Obesity-Related Heart Failure and Type 2 Diabetes. N Engl J Med. 2024 Apr 18; 390 (15):1394-1407 Epub 2024 Apr 06
    View PubMed
  84. Ameri P, Mercurio V, Pollesello P, Anker MS, Backs J, Bayes-Genis A, Borlaug BA, Burkhoff D, Caravita S, Chan SY, de Man F, Giannakoulas G, Gonzalez A, Guazzi M, Hassoun PM, Hemnes AR, Maack C, Madden B, Melenovsky V, Muller OJ, Papp Z, Pullamsetti SS, Rainer PP, Redfield MM, Rich S, Schiattarella GG, Skaara H, Stellos K, Tedford RJ, Thum T, Vachiery JL, van der Meer P, Van Linthout S, Pruszczyk P, Seferovic P, Coats AJS, Metra M, Rosano G, Rosenkranz S, Tocchetti CG. A roadmap for therapeutic discovery in pulmonary hypertension associated with left heart failure. A scientific statement of the Heart Failure Association (HFA) of the ESC and the ESC Working Group on Pulmonary Circulation & Right Ventricular Function. Eur J Heart Fail. 2024 Apr; 26 (4):707-729 Epub 2024 Apr 19
    View PubMed
  85. Monzo L, Tupy M, Borlaug BA, Reichenbach A, Jurcova I, Benes J, Mlateckova L, Ters J, Kautzner J, Melenovsky V. Pressure overload is associated with right ventricular dyssynchrony in heart failure with reduced ejection fraction. ESC Heart Fail. 2024 Apr; 11 (2):1097-1109 Epub 2024 Jan 23
    View PubMed
  86. Borlaug BA, Strong M. Heart Failure Solutions: The PeriCut Device as a Treatment for HFpEF. JACC Basic Transl Sci. 2024 Apr; 9 (4):448-450 Epub 2024 Apr 22
    View PubMed
  87. Larson K, Omar M, Sorimachi H, Omote K, Alogna A, Popovic D, Tada A, Doi S, Naser J, Reddy YNV, Redfield MM, Borlaug BA. Clinical phenogroup diversity and multiplicity: Impact on mechanisms of exercise intolerance in heart failure with preserved ejection fraction. Eur J Heart Fail. 2024 Mar; 26 (3):564-577 Epub 2024 Jan 18
    View PubMed
  88. Hoedemakers S, Verwerft J, Reddy YNV, Delvaux R, Stroobants S, Jogani S, Claessen G, Droogmans S, Cosyns B, Borlaug BA, Herbots L, Verbrugge FH. Cardiac dysfunction rather than aortic valve stenosis severity drives exercise intolerance and adverse haemodynamics. Eur Heart J Cardiovasc Imaging. 2024 Feb 22; 25 (3):302-312
    View PubMed
  89. Omote K, Sorimachi H, Obokata M, Verbrugge FH, Omar M, Popovic D, Reddy YNV, Pislaru SV, Pellikka PA, Borlaug BA. Biatrial myopathy in heart failure with preserved ejection fraction. Eur J Heart Fail. 2024 Feb; 26(2):288-298. Epub 2023 Dec 13.
    View PubMed
  90. Borlaug BA, Koepp KE, Reddy YNV, Obokata M, Sorimachi H, Freund M, Haberman D, Sweere K, Weber KL, Overholt EA, Safe BA, Omote K, Omar M, Popovic D, Acker NG, Gladwin MT, Olson TP, Carter RE. Inorganic Nitrite to Amplify the Benefits and Tolerability of Exercise Training in Heart Failure With Preserved Ejection Fraction: The INABLE-Training Trial. Mayo Clin Proc. 2024 Feb; 99(2):206-217. Epub 2023 Dec 21.
    View PubMed
  91. Miranda WR, Jain CC, Borlaug BA, Connolly HM, Burchill LJ, Van De Bruaene A, Egbe AC. Exercise catheterization in adults post-Fontan with normal and abnormal haemodynamic criteria: Insights into normal Fontan physiology. Eur J Heart Fail. 2024 Feb; 26 (2):314-323 Epub 2024 Feb 01
    View PubMed
  92. Egbe AC, Younis A, Miranda WR, Jain CC, Connolly HM, Borlaug BA. Determinants and prognostic implications of left atrial reverse remodelling after coarctation of aorta repair in adults. Eur Heart J Cardiovasc Imaging. 2024 Jan 29; 25 (2):249-256
    View PubMed
  93. Kosiborod MN, Verma S, Borlaug BA, Butler J, Davies MJ, Jon Jensen T, Rasmussen S, Erlang Marstrand P, Petrie MC, Shah SJ, Ito H, Schou M, Melenovsky V, Abhayaratna W, Kitzman DW, STEP-HFpEF Trial Committees and Investigators. Effects of Semaglutide on Symptoms, Function, and Quality of Life in Patients With Heart Failure With Preserved Ejection Fraction and Obesity: A Prespecified Analysis of the STEP-HFpEF Trial. Circulation. 2024 Jan 16; 149 (3):204-216 Epub 2023 Nov 12
    View PubMed
  94. Lee E, Ito S, Miranda WR, Lopez-Jimenez F, Kane GC, Asirvatham SJ, Noseworthy PA, Friedman PA, Carter RE, Borlaug BA, Attia ZI, Oh JK. Artificial intelligence-enabled ECG for left ventricular diastolic function and filling pressure. NPJ Digit Med. 2024 Jan 6; 7 (1):4 Epub 2024 Jan 06
    View PubMed
  95. Alogna A, Berboth L, Faragli A, Otvos J, Lo Muzio FP, di Mauro V, Modica J, Quarta E, Semmler L, Deissler PM, Berger YW, Tran KL, de Marchi B, Longinotti-Buitoni G, Degli Esposti L, Guillot E, Bazile D, Iafisco M, Dotti A, Bang ML, de Luca C, Brandenberger C, Benazzi L, di Silvestre D, de Palma A, Primessnig U, Hohendanner F, Perna S, Buttini F, Colombo P, Muhlfeld C, Steendijk P, Mauri P, Tschope C, Borlaug B, Pieske BM, Attanasio P, Post H, Heinzel FR, Catalucci D. Lung-to-Heart Nano-in-Micro Peptide Promotes Cardiac Recovery in a Pig Model of Chronic Heart Failure. J Am Coll Cardiol. 2024 Jan 2; 83 (1):47-59
    View PubMed
  96. Litwin SE, Komtebedde J, Seidler T, Borlaug BA, Winkler S, Solomon SD, Eicher JC, Mazimba S, Khawash R, Sverdlov AL, Hummel SL, Bugger H, Boenner F, Hoendermis E, Cikes M, Demers C, Silva G, van Empel V, Starling RC, Penicka M, Cutlip DE, Leon MB, Kitzman DW, van Veldhuisen DJ, Shah SJ, REDUCE LAP-HF Investigators and Research Staff. Obesity in heart failure with preserved ejection fraction: Insights from the REDUCE LAP-HF II trial. Eur J Heart Fail. 2024 Jan; 26 (1):177-189 Epub 2023 Dec 07
    View PubMed
  97. Sindone A, Kosiborod M, Petrie MC, Borlaug BA, Butler J, Davies MJ, Hovingh GK, Kitzman DW, Moller DV, Treppendahl MB, Verma S, Jensen TJ, Liisberg K, Lindegaard ML, Shah SJ. Once-weekly semaglutide in patients with heart failure with preserved ejection fraction, obesity and type 2 diabetes: main results from the step-hfpef dm trial. Obesity Research & Clinical Practice. 2024; 18 (5 Suppl 1):S37
  98. Litwin SE, Komtebedde J, Borlaug BA, Kaye DM, Hasenfub G, Kawash R, Hoendermis E, Hummel SL, Cikes M, Gustafsson F, Chung ES, Mohan RC, Sverdlov AL, Swarup V, Winkler S, Hayward CS, Bergmann MW, Bugger H, McKenzie S, Nair A, Rieth A, Burkhoff D, Cutlip DE, Solomon SD, van Veldhuisen DJ, Leon MB, Shah SJ. Long term safety and outcomes after atrial shunting for heart failure with preserved or mildly reduced ejection fraction: 5-year and 3-year follow-up in the reduce lap-hf i and ii trials. American Heart Journal. 2024; 278:106-16
  99. Sindone A, Kosiborod M, Abildstrom SZ, Borlaug BA, Butler J, Rasmussen S, Davies MJ, Hovingh GK, Kitzman DW, Lindegaard ML, Moller DV, Shah SJ, Treppendahl MB, Verma S, Petrie MC. Once-weekly semaglutide in heart failure with preserved ejection fraction and obesity: main results from the step-hfpef trial. Obesity Research & Clinical Practice. 2024; 18 (5 Suppl 1):S36-7
  100. Kosiborod MN, Petrie MC, Borlaug BA. Response by Kosiborod et al to letter regarding article, "effects of Semaglutide on symptoms, function, and quality of life in patients with heart failure with preserved ejection fraction and obesity: a prespecified analysis of the STEP-HFpEF trial". Circulation. 2024; 150 (10):e226-7
  101. Naser JA, Lee E, Scott CG, Kennedy AM, Pellikka PA, Lin G, Pislaru SV, Borlaug BA. Prevalence and incidence of diastolic dysfunction in atrial fibrillation: clinical implications. Eur Heart J. 2023 Dec 21; 44 (48):5049-5060
    View PubMed
  102. Butler J, Abildstrom SZ, Borlaug BA, Davies MJ, Kitzman DW, Petrie MC, Shah SJ, Verma S, Abhayaratna WP, Chopra V, Ezekowitz JA, Fu M, Ito H, Lelonek M, Nunez J, Perna E, Schou M, Senni M, van der Meer P, von Lewinski D, Wolf D, Altschul RL, Rasmussen S, Kosiborod MN. Semaglutide in Patients With Obesity and Heart Failure Across Mildly Reduced or Preserved Ejection Fraction. J Am Coll Cardiol. 2023 Nov 28; 82 (22):2087-2096 Epub 2023 Oct 08
    View PubMed
  103. Borlaug BA, Schaff HV, Asirvatham SJ, Koepp KE, Mauermann WJ, Rowse PG. Surgical pericardiotomy to treat heart failure with preserved ejection fraction: a first clinical study. Eur Heart J. 2023 Nov 21; 44 (44):4719-4721
    View PubMed
  104. Alogna A, Koepp KE, Sabbah M, Espindola Netto JM, Jensen MD, Kirkland JL, Lam CSP, Obokata M, Petrie MC, Ridker PM, Sorimachi H, Tchkonia T, Voors A, Redfield MM, Borlaug BA. Interleukin-6 in Patients With Heart Failure and Preserved Ejection Fraction. JACC Heart Fail. 2023 Nov; 11 (11):1549-1561 Epub 2023 Aug 09
    View PubMed
  105. Lewis GD, Gosch K, Cohen LP, Nassif ME, Windsor SL, Borlaug BA, Kitzman DW, Shah SJ, Khumri T, Umpierrez G, Lamba S, Sharma K, Khan SS, Kosiborod MN, Sauer AJ. Effect of Dapagliflozin on 6-Minute Walk Distance in Heart Failure With Preserved Ejection Fraction: PRESERVED-HF. Circ Heart Fail 2023 Nov; 16 (11):e010633 Epub 2023 Oct 23
    View PubMed
  106. Verma S, Borlaug BA, Butler J, Davies MJ, Kitzman DW, Petrie MC, Shah SJ, Dhingra NK, Kosiborod MN. A big STEP for treatment of heart failure with preserved ejection fraction. Cell Metab. 2023 Oct 3; 35 (10):1681-1687 Epub 2023 Aug 28
    View PubMed
  107. Morgen CS, Haase CL, Oral TK, Schnecke V, Varbo A, Borlaug BA. Obesity, Cardiorenal Comorbidities, and Risk of Hospitalization in Patients With Heart Failure With Preserved Ejection Fraction. Mayo Clin Proc. 2023 Oct; 98 (10):1458-1468 Epub 2023 Aug 09
    View PubMed
  108. Kosiborod MN, Abildstrom SZ, Borlaug BA, Butler J, Rasmussen S, Davies M, Hovingh GK, Kitzman DW, Lindegaard ML, Moller DV, Shah SJ, Treppendahl MB, Verma S, Abhayaratna W, Ahmed FZ, Chopra V, Ezekowitz J, Fu M, Ito H, Lelonek M, Melenovsky V, Merkely B, Nunez J, Perna E, Schou M, Senni M, Sharma K, Van der Meer P, von Lewinski D, Wolf D, Petrie MC, STEP-HFpEF Trial Committees and Investigators. Semaglutide in Patients with Heart Failure with Preserved Ejection Fraction and Obesity. N Engl J Med. 2023 Sep 21; 389 (12):1069-1084 Epub 2023 Aug 25
    View PubMed
  109. Borlaug BA, Reddy YNV, Braun A, Sorimachi H, Omar M, Popovic D, Alogna A, Jensen MD, Carter R. Cardiac and Metabolic Effects of Dapagliflozin in Heart Failure With Preserved Ejection Fraction: The CAMEO-DAPA Trial. Circulation. 2023 Sep 05; 148(10):834-844. Epub 2023 Aug 03.
    View PubMed
  110. Keck C, Gregoski M, Litwin S, Borlaug BA, Fudim M, Tedford RJ, Houston BA. Decoupling of Hemodynamics and Congestive Symptoms in Obese Patients With Heart Failure. J Card Fail. 2023 Sep; 29 (9):1249-1256 Epub 2023 Mar 23
    View PubMed
  111. Borlaug BA, Kitzman DW, Davies MJ, Rasmussen S, Barros E, Butler J, Einfeldt MN, Hovingh GK, Moller DV, Petrie MC, Shah SJ, Verma S, Abhayaratna W, Ahmed FZ, Chopra V, Ezekowitz J, Fu M, Ito H, Lelonek M, Melenovsky V, Nunez J, Perna E, Schou M, Senni M, van der Meer P, Von Lewinski D, Wolf D, Kosiborod MN. Semaglutide in HFpEF across obesity class and by body weight reduction: a prespecified analysis of the STEP-HFpEF trial. Nat Med. 2023 Sep; 29 (9):2358-2365 Epub 2023 Aug 27
    View PubMed
  112. Warner B, Bruhn EJ, Olson TP, Bissen TG, Borlaug BA, Smith JR. Inspiratory muscle strength is related to exertional dyspnoea in heart failure with preserved ejection fraction. Eur J Heart Fail 2023 Sep; 25 (9):1716-1717 Epub 2023 Aug 02
    View PubMed
  113. Borlaug BA, Testani JM. SGLT2 inhibitors and diuretics in heart failure: clicking reset on the renal volume setpoint? Eur Heart J 2023 Aug 14; 44 (31):2944-2946
    View PubMed
  114. Egbe AC, Miranda WR, Connolly HM, Kullo IJ, Borlaug BA. Daytime Versus Nighttime Ambulatory Blood Pressure Monitoring in Coarctation of Aorta. Hypertension. 2023 Aug; 80 (8):e134-e136 Epub 2023 May 10
    View PubMed
  115. Kosiborod MN, Abildstrom SZ, Borlaug BA, Butler J, Christensen L, Davies M, Hovingh KG, Kitzman DW, Lindegaard ML, Moller DV, Shah SJ, Treppendahl MB, Verma S, Petrie MC. Design and Baseline Characteristics of STEP-HFpEF Program Evaluating Semaglutide in Patients With Obesity HFpEF Phenotype. JACC Heart Fail. 2023 Aug; 11 (8 Pt 1):1000-1010 Epub 2023 May 21
    View PubMed
  116. Litwin SE, Komtebedde J, Hu M, Burkhoff D, Hasenfuss G, Borlaug BA, Solomon SD, Zile MR, Mohan RC, Khawash R, Sverdlov AL, Fail P, Chung ES, Kaye DM, Blair J, Eicher JC, Hummel SL, Zirlik A, Westenfeld R, Hayward C, Gorter TM, Demers C, Shetty R, Lewis G, Starling RC, Patel S, Gupta DK, Morsli H, Penicka M, Cikes M, Gustafsson F, Silvestry FE, Rowin EJ, Cutlip DE, Leon MB, Kitzman DW, Kleber FX, Shah SJ, REDUCE LAP-HF Investigators and Research Staff. Exercise-Induced Left Atrial Hypertension in Heart Failure With Preserved Ejection Fraction. JACC Heart Fail. 2023 Aug; 11 (8 Pt 2):1103-1117 Epub 2023 Mar 20
    View PubMed
  117. Omote K, Borlaug BA. Left Atrial Myopathy in Heart Failure With Preserved Ejection Fraction. Circ J. 2023 Jul 25; 87 (8):1039-1046 Epub 2021 Oct 12
    View PubMed
  118. Nassif ME, Windsor SL, Gosch K, Borlaug BA, Husain M, Inzucchi SE, Kitzman DW, McGuire DK, Pitt B, Scirica BM, Shah SJ, Umpierrez G, Austin BA, Lamba S, Khumri T, Sharma K, Kosiborod MN. Dapagliflozin Improves Heart Failure Symptoms and Physical Limitations Across the Full Range of Ejection Fraction: Pooled Patient-Level Analysis From DEFINE-HF and PRESERVED-HF Trials. Circ Heart Fail. 2023 Jul; 16 (7):e009837 Epub 2023 May 19
    View PubMed
  119. Alogna A, Omar M, Popovic D, Sorimachi H, Omote K, Reddy YNV, Pieske B, Borlaug BA. Biventricular cardiac power reserve in heart failure with preserved ejection fraction. Eur J Heart Fail. 2023 Jul; 25(7):956-966. Epub 2023 Apr 24.
    View PubMed
  120. Reddy YNV, Borlaug BA. Rate-Adaptive Atrial Pacing for Heart Failure With Preserved Ejection Fraction-Reply. JAMA 2023 Jun 20; 329 (23):2096-2097
    View PubMed
  121. Eder M, Griffin M, Moreno-Villagomez J, Bellumkonda L, Maulion C, Asher J, Wilson FP, Cox ZL, Ivey-Miranda JB, Rao VS, Butler J, Borlaug BA, McCallum W, Ramos-Mastache D, Testani JM. The importance of forward flow and venous congestion in diuretic response in acute heart failure: Insights from the ESCAPE trial. Int J Cardiol. 2023 Jun 15; 381:57-61 Epub 2023 Apr 05
    View PubMed
  122. Martens P, Yu S, Larive B, Borlaug BA, Erzurum SC, Farha S, Finet JE, Grunig G, Hemnes AR, Hill NS, Horn EM, Jacob M, Kwon DH, Park MM, Rischard FP, Rosenzweig EB, Wilcox JD, Tang WHW, PVDOMICS Study Group. Iron deficiency in pulmonary vascular disease: pathophysiological and clinical implications. Eur Heart J. 2023 Jun 9; 44 (22):1979-1991
    View PubMed
  123. Gard EK, Beale AL, Telles F, Silvestry FE, Hanff T, Hummel SL, Litwin SE, Petrie MC, Shah SJ, Borlaug BA, Burkhoff D, Komtebedde J, Kaye DM, Nanayakkara S. Left atrial enlargement is associated with pulmonary vascular disease in heart failure with preserved ejection fraction. Eur J Heart Fail. 2023 Jun; 25 (6):806-814 Epub 2023 Mar 15
    View PubMed
  124. Borlaug BA, Sharma K, Shah SJ, Ho JE. Heart Failure With Preserved Ejection Fraction: JACC Scientific Statement. J Am Coll Cardiol. 2023 May 9; 81 (18):1810-1834 Epub 2023 Apr 19
    View PubMed
  125. Sheridan WS, Wetterling F, Testani JM, Borlaug BA, Fudim M, Damman K, Gray A, Gaines P, Poloczek M, Madden S, Tucker J, Buxo T, Gaul R, Corcoran L, Sweeney F, Burkhoff D. Safety and performance of a novel implantable sensor in the inferior vena cava under acute and chronic intravascular volume modulation. Eur J Heart Fail. 2023 May; 25 (5):754-763 Epub 2023 Mar 09
    View PubMed
  126. Popovic D, Alogna A, Omar M, Sorimachi H, Omote K, Reddy YNV, Redfield MM, Burkhoff D, Borlaug BA. Ventricular stiffening and chamber contracture in heart failure with higher ejection fraction. Eur J Heart Fail. 2023 May; 25(5):657-668. Epub 2023 Apr 12.
    View PubMed
  127. Miranda WR, Jain CC, Borlaug BA, Jaffe AS, Connolly HM, Burchill LJ, Egbe AC. Exercise Capacity, NT-proBNP, and Exercise Hemodynamics in Adults Post-Fontan. J Am Coll Cardiol. 2023 Apr 25; 81 (16):1590-1600
    View PubMed
  128. Pugliese NR, De Biase N, Del Punta L, Balletti A, Armenia S, Buralli S, Mengozzi A, Taddei S, Metra M, Pagnesi M, Borlaug BA, Williams B, Masi S. Deep phenotype characterization of hypertensive response to exercise: implications on functional capacity and prognosis across the heart failure spectrum. Eur J Heart Fail. 2023 Apr; 25 (4):497-509 Epub 2023 Mar 29
    View PubMed
  129. Posada-Martinez EL, Cox ZL, Cano-Nieto MM, Ibarra-Marquez ND, Moreno-Villagomez J, Gudino-Bravo P, Arias-Godinez JA, Lopez-Gil S, Madero M, Rao VS, Mebazaa A, Burkhoff D, Cowie MR, Fudim M, Damman K, Borlaug BA, Testani JM, Ivey-Miranda JB. Changes in the Inferior Vena Cava Are More Sensitive Than Venous Pressure During Fluid Removal: A Proof-of-Concept Study. J Card Fail. 2023 Apr; 29 (4):463-472 Epub 2022 Oct 13
    View PubMed
  130. Fayyaz AU, Sabbah MS, Dasari S, Griffiths LG, DuBrock HM, Wang Y, Charlesworth MC, Borlaug BA, Jenkins SM, Edwards WD, Redfield MM. Histologic and proteomic remodeling of the pulmonary veins and arteries in a porcine model of chronic pulmonary venous hypertension. Cardiovasc Res. 2023 Mar 17; 119 (1):268-282
    View PubMed
  131. Redfield MM, Borlaug BA. Heart Failure With Preserved Ejection Fraction: A Review. JAMA. 2023 Mar 14; 329 (10):827-838
    View PubMed
  132. Reddy YNV, Koepp KE, Carter R, Win S, Jain CC, Olson TP, Johnson BD, Rea R, Redfield MM, Borlaug BA. Rate-Adaptive Atrial Pacing for Heart Failure With Preserved Ejection Fraction: The RAPID-HF Randomized Clinical Trial. JAMA. 2023 Mar 14; 329(10):801-809.
    View PubMed
  133. Natov PS, Ivey-Miranda JB, Cox ZL, Moreno-Villagomez J, Maulion C, Bellumkonda L, Shlipak MG, Estrella MM, Borlaug BA, Rao VS, Testani JM. Improvement in Renal Function During the Treatment of Acute Decompensated Heart Failure: Relationship With Markers of Renal Tubular Injury and Prognostic Importance. Circ Heart Fail. 2023 Mar; 16 (3):e009776 Epub 2023 Jan 26
    View PubMed
  134. Borlaug BA, Jensen MD, Kitzman DW, Lam CSP, Obokata M, Rider OJ. Obesity and heart failure with preserved ejection fraction: new insights and pathophysiological targets. Cardiovasc Res. 2023 Feb 3; 118 (18):3434-3450
    View PubMed
  135. Peters AE, Tromp J, Shah SJ, Lam CSP, Lewis GD, Borlaug BA, Sharma K, Pandey A, Sweitzer NK, Kitzman DW, Mentz RJ. Phenomapping in heart failure with preserved ejection fraction: insights, limitations, and future directions. Cardiovasc Res. 2023 Feb 3; 118 (18):3403-3415
    View PubMed
  136. Dong X, Strudwick M, Wang WY, Borlaug BA, van der Geest RJ, Ng AC, Delgado V, Bax JJ, Ng AC. Impact of body mass index and diabetes on myocardial fat content, interstitial fibrosis and function. Int J Cardiovasc Imaging. 2023 Feb; 39 (2):379-390 Epub 2022 Oct 28
    View PubMed
  137. Omote K, Verbrugge FH, Sorimachi H, Omar M, Popovic D, Obokata M, Reddy YNV, Borlaug BA. Central haemodynamic abnormalities and outcome in patients with unexplained dyspnoea. Eur J Heart Fail. 2023 Feb; 25(2):185-196. Epub 2022 Dec 15.
    View PubMed
  138. Henry JA, Abdesselam I, Deal O, Lewis AJ, Rayner J, Bernard M, Dutour A, Gaborit B, Kober F, Soghomonian A, Sgromo B, Byrne J, Bege T, Neubauer S, Borlaug BA, Rider OJ. Changes in epicardial and visceral adipose tissue depots following bariatric surgery and their effect on cardiac geometry. Front Endocrinol (Lausanne). 2023; 14:1092777 Epub 2023 Jan 25
    View PubMed
  139. Miranda WR, Borlaug BA, Jain CC, Anderson JH, Hagler DJ, Connolly HM, Egbe AC. Exercise-induced changes in pulmonary artery wedge pressure in adults post-Fontan versus heart failure with preserved ejection fraction and non-cardiac dyspnoea. Eur J Heart Fail. 2023 Jan; 25(1):17-25. Epub 2022 Oct 23.
    View PubMed
  140. Egbe AC, Miranda WR, Jain CC, Borlaug BA, Connolly HM. Prognostic Implications of Exercise-Induced Hypertension in Adults With Repaired Coarctation of Aorta. Hypertension. 2022 Dec; 79(12):2796-2805. Epub 2022 Oct 12.
    View PubMed
  141. Egbe AC, Miranda WR, Reddy YNV, Anderson JH, Andi K, Goda A, Abozied O, Connolly HM, Borlaug BA. Prognostic Value of the H(2)FPEF Score in Adults With Repaired Coarctation of Aorta. JACC Adv. 2022 Dec; 1 (5):100130 Epub 2022 Nov 16
    View PubMed
  142. Andersen MJ, Wolsk E, Bakkestrom R, Christensen N, Carter-Storch R, Omar M, Dahl JS, Frederiksen PH, Borlaug B, Gustafsson F, Hassager C, Moller JE. Pressure-flow responses to exercise in aortic stenosis, mitral regurgitation and diastolic dysfunction. Heart. 2022 Nov 10; 108 (23):1895-1903
    View PubMed
  143. Omote K, Hsu S, Borlaug BA. Hemodynamic Assessment in Heart Failure with Preserved Ejection Fraction. Cardiol Clin. 2022 Nov; 40 (4):459-472
    View PubMed
  144. Litwin SE, Borlaug BA, Komtebedde J, Shah SJ. Update on Atrial Shunt Therapy for Treatment of Heart Failure. Struct Heart. 2022 Nov; 6 (6):100090 Epub 2022 Sept 21
    View PubMed
  145. Hammer SM, Bruhn EJ, Bissen TG, Muer JD, Villarraga N, Borlaug BA, Olson TP, Smith JR. Inspiratory and leg muscle blood flows during inspiratory muscle metaboreflex activation in heart failure with preserved ejection fraction. J Appl Physiol (1985). 2022 Nov 1; 133 (5):1202-1211 Epub 2022 Oct 13
    View PubMed
  146. Sorimachi H, Obokata M, Omote K, Reddy YNV, Takahashi N, Koepp KE, Ng ACT, Rider OJ, Borlaug BA. Long-Term Changes in Cardiac Structure and Function Following Bariatric Surgery. J Am Coll Cardiol. 2022 Oct 18; 80 (16):1501-1512
    View PubMed
  147. Davies DR, Redfield MM, Scott CG, Minamisawa M, Grogan M, Dispenzieri A, Chareonthaitawee P, Shah AM, Shah SJ, Wehbe RM, Solomon SD, Reddy YNV, Borlaug BA, AbouEzzeddine OF. A Simple Score to Identify Increased Risk of Transthyretin Amyloid Cardiomyopathy in Heart Failure With Preserved Ejection Fraction. JAMA Cardiol. 2022 Oct 1; 7 (10):1036-1044
    View PubMed
  148. Omote K, Sorimachi H, Obokata M, Reddy YNV, Verbrugge FH, Omar M, DuBrock HM, Redfield MM, Borlaug BA. Pulmonary vascular disease in pulmonary hypertension due to left heart disease: pathophysiologic implications. Eur Heart J. 2022 Sep 21; 43 (36):3417-3431
    View PubMed
  149. Lewis AJM, Abdesselam I, Rayner JJ, Byrne J, Borlaug BA, Neubauer S, Rider OJ. Adverse right ventricular remodelling, function, and stress responses in obesity: insights from cardiovascular magnetic resonance. Eur Heart J Cardiovasc Imaging. 2022 Sep 10; 23 (10):1383-1390
    View PubMed
  150. Reddy YNV, Kaye DM, Handoko ML, van de Bovenkamp AA, Tedford RJ, Keck C, Andersen MJ, Sharma K, Trivedi RK, Carter RE, Obokata M, Verbrugge FH, Redfield MM, Borlaug BA. Diagnosis of Heart Failure With Preserved Ejection Fraction Among Patients With Unexplained Dyspnea. JAMA Cardiol. 2022 Sep 1; 7 (9):891-899
    View PubMed
  151. Hemnes AR, Leopold JA, Radeva MK, Beck GJ, Abidov A, Aldred MA, Barnard J, Rosenzweig EB, Borlaug BA, Chung WK, Comhair SAA, Desai AA, Dubrock HM, Erzurum SC, Finet JE, Frantz RP, Garcia JGN, Geraci MW, Gray MP, Grunig G, Hassoun PM, Highland KB, Hill NS, Hu B, Kwon DH, Jacob MS, Jellis CL, Larive AB, Lempel JK, Maron BA, Mathai SC, McCarthy K, Mehra R, Nawabit R, Newman JH, Olman MA, Park MM, Ramos JA, Renapurkar RD, Rischard FP, Sherer SG, Tang WHW, Thomas JD, Vanderpool RR, Waxman AB, Wilcox JD, Yuan JX, Horn EM, PVDOMICS Study Group. Clinical Characteristics and Transplant-Free Survival Across the Spectrum of Pulmonary Vascular Disease. J Am Coll Cardiol. 2022 Aug 16; 80 (7):697-718
    View PubMed
  152. Goyal P, Kim M, Krishnan U, Mccullough SA, Cheung JW, Kim LK, Pandey A, Borlaug BA, Horn EM, Safford MM, Kamel H. Post-operative atrial fibrillation and risk of heart failure hospitalization. Eur Heart J. 2022 Aug 14; 43 (31):2971-2980
    View PubMed
  153. Sorimachi H, Omote K, Omar M, Popovic D, Verbrugge FH, Reddy YNV, Lin G, Obokata M, Miles JM, Jensen MD, Borlaug BA. Sex and central obesity in heart failure with preserved ejection fraction. Eur J Heart Fail. 2022 Aug; 24 (8):1359-1370 Epub 2022 June 06
    View PubMed
  154. Fudim M, Fail PS, Litwin SE, Shaburishvili T, Goyal P, Hummel SL, Borlaug BA, Mohan RC, Patel RB, Mitter SS, Klein L, Rocha-Singh K, Patel MR, Reddy VY, Burkhoff D, Shah SJ. Endovascular ablation of the right greater splanchnic nerve in heart failure with preserved ejection fraction: early results of the REBALANCE-HF trial roll-in cohort. Eur J Heart Fail. 2022 Aug; 24 (8):1410-1414 Epub 2022 May 29
    View PubMed
  155. Guazzi M, Wilhelm M, Halle M, Van Craenenbroeck E, Kemps H, de Boer RA, Coats AJS, Lund L, Mancini D, Borlaug B, Filippatos G, Pieske B. Exercise testing in heart failure with preserved ejection fraction: an appraisal through diagnosis, pathophysiology and therapy - A clinical consensus statement of the Heart Failure Association and European Association of Preventive Cardiology of the European Society of Cardiology. Eur J Heart Fail. 2022 Aug; 24 (8):1327-1345 Epub 2022 July 31
    View PubMed
  156. Reddy YNV, Borlaug BA, Gersh BJ. Management of Atrial Fibrillation Across the Spectrum of Heart Failure With Preserved and Reduced Ejection Fraction. Circulation. 2022 Jul 26; 146 (4):339-357 Epub 2022 July 25
    View PubMed
  157. Jentzer JC, Reddy YN, Rosenbaum AN, Dunlay SM, Borlaug BA, Hollenberg SM. Outcomes and Predictors of Mortality Among Cardiac Intensive Care Unit Patients With Heart Failure. J Card Fail. 2022 Jul; 28 (7):1088-1099 Epub 2022 Apr 02
    View PubMed
  158. Jellis CL, Park MM, Abidov A, Borlaug BA, Brittain EL, Frantz R, Hassoun PM, Horn EM, Jaber WA, Jiwon K, Karas MG, Kwon D, Leopold JA, Maron B, Mathai SC, Mehra R, Rischard F, Rosenzweig EB, Tang WHW, Vanderpool R, Thomas JD, PVDOMICS Study Group. Comprehensive echocardiographic evaluation of the right heart in patients with pulmonary vascular diseases: the PVDOMICS experience. Eur Heart J Cardiovasc Imaging. 2022 Jun 21; 23 (7):958-969
    View PubMed
  159. Verbrugge FH, Borlaug BA. Heart failure with normal natriuretic peptide levels: more fat, and that is the main problem. Eur Heart J 2022 Jun 14; 43 (23):2248-2249
    View PubMed
  160. Miranda WR, Jain CC, Borlaug BA, Connolly HM, Egbe AC. Exercise invasive hemodynamics in adults post-Fontan: A novel tool in understanding functional limitation and liver disease. J Heart Lung Transplant. 2022 Jun; 41(6):704-707. Epub 2022 Mar 09.
    View PubMed
  161. Ezzeddine FM, Bois MC, Borlaug BA. Unloading the right to fill the left: vasodilation to treat hypotension: a case report. Eur Heart J Case Rep. 2022 Jun; 6 (6):ytac179 Epub 2022 Apr 23
    View PubMed
  162. Borlaug BA, Blair J, Bergmann MW, Bugger H, Burkhoff D, Bruch L, Celermajer DS, Claggett B, Cleland JGF, Cutlip DE, Dauber I, Eicher JC, Gao Q, Gorter TM, Gustafsson F, Hayward C, van der Heyden J, Hasenfuss G, Hummel SL, Kaye DM, Komtebedde J, Massaro JM, Mazurek JA, McKenzie S, Mehta SR, Petrie MC, Post MC, Nair A, Rieth A, Silvestry FE, Solomon SD, Trochu JN, Van Veldhuisen DJ, Westenfeld R, Leon MB, Shah SJ, REDUCE LAP-HF-II Investigators. Latent Pulmonary Vascular Disease May Alter the Response to Therapeutic Atrial Shunt Device in Heart Failure. Circulation. 2022 May 24; 145 (21):1592-1604 Epub 2022 Mar 31
    View PubMed
  163. Verbrugge FH, Omote K, Reddy YNV, Sorimachi H, Obokata M, Borlaug BA. Heart failure with preserved ejection fraction in patients with normal natriuretic peptide levels is associated with increased morbidity and mortality. Eur Heart J. 2022 May 21; 43 (20):1941-1951
    View PubMed
  164. Fudim M, Kaye DM, Borlaug BA, Shah SJ, Rich S, Kapur NK, Costanzo MR, Brener MI, Sunagawa K, Burkhoff D. Venous Tone and Stressed Blood Volume in Heart Failure: JACC Review Topic of the Week. J Am Coll Cardiol. 2022 May 10; 79 (18):1858-1869
    View PubMed
  165. van de Bovenkamp AA, Wijkstra N, Oosterveer FPT, Vonk Noordegraaf A, Bogaard HJ, van Rossum AC, de Man FS, Borlaug BA, Handoko ML. The Value of Passive Leg Raise During Right Heart Catheterization in Diagnosing Heart Failure With Preserved Ejection Fraction. Circ Heart Fail. 2022 Apr; 15 (4):e008935 Epub 2022 Mar 21
    View PubMed
  166. Smith JR, Joyner MJ, Curry TB, Borlaug BA, Keller-Ross ML, Van Iterson EH, Olson TP. Influence of locomotor muscle group III/IV afferents on cardiovascular and ventilatory responses in human heart failure during submaximal exercise. J Appl Physiol (1985). 2022 Apr 1; 132 (4):903-914 Epub 2022 Feb 24
    View PubMed
  167. Jain CC, Tschirren J, Reddy YNV, Melenovsky V, Redfield M, Borlaug BA. Subclinical Pulmonary Congestion and Abnormal Hemodynamics in Heart Failure With Preserved Ejection Fraction. JACC Cardiovasc Imaging. 2022 Apr; 15 (4):629-637 Epub 2021 Nov 17
    View PubMed
  168. Shah SJ, Borlaug BA, Chung ES, Cutlip DE, Debonnaire P, Fail PS, Gao Q, Hasenfuss G, Kahwash R, Kaye DM, Litwin SE, Lurz P, Massaro JM, Mohan RC, Ricciardi MJ, Solomon SD, Sverdlov AL, Swarup V, van Veldhuisen DJ, Winkler S, Leon MB, REDUCE LAP-HF II investigators. Atrial shunt device for heart failure with preserved and mildly reduced ejection fraction (REDUCE LAP-HF II): a randomised, multicentre, blinded, sham-controlled trial. Lancet. 2022 Mar 19; 399 (10330):1130-1140 Epub 2022 Feb 01
    View PubMed
  169. Jentzer JC, Wiley BM, Reddy YNV, Barnett C, Borlaug BA, Solomon MA. Epidemiology and outcomes of pulmonary hypertension in the cardiac intensive care unit. Eur Heart J Acute Cardiovasc Care. 2022 Mar 16; 11 (3):230-241
    View PubMed
  170. Omar M, Jensen J, Burkhoff D, Frederiksen PH, Kistorp C, Videbaek L, Poulsen MK, Gustafsson F, Kober L, Borlaug BA, Schou M, Moller JE. Effect of Empagliflozin on Blood Volume Redistribution in Patients With Chronic Heart Failure and Reduced Ejection Fraction: An Analysis From the Empire HF Randomized Clinical Trial. Circ Heart Fail. 2022 Mar; 15 (3):e009156 Epub 2021 Nov 08
    View PubMed
  171. Burstein B, Anand V, Ternus B, Tabi M, Anavekar NS, Borlaug BA, Barsness GW, Kane GC, Oh JK, Jentzer JC. Noninvasive echocardiographic cardiac power output predicts mortality in cardiac intensive care unit patients. Am Heart J. 2022 Mar; 245:149-159 Epub 2021 Dec 22
    View PubMed
  172. Ivey-Miranda JB, Wetterling F, Gaul R, Sheridan S, Asher JL, Rao VS, Maulion C, Mahoney D, Mebazaa A, Gray AP, Burkhoff D, Cowie MR, Cox ZL, Butler J, Fudim M, McDonald K, Damman K, Borlaug BA, Testani JM. Changes in inferior vena cava area represent a more sensitive metric than changes in filling pressures during experimental manipulation of intravascular volume and tone. Eur J Heart Fail. 2022 Mar; 24 (3):455-462 Epub 2022 Jan 11
    View PubMed
  173. Martens P, Herbots L, Timmermans P, Verbrugge FH, Dendale P, Borlaug BA, Verwerft J. Cardiopulmonary Exercise Testing with Echocardiography to Identify Mechanisms of Unexplained Dyspnea. J Cardiovasc Transl Res. 2022 Feb; 15 (1):116-130 Epub 2021 June 10
    View PubMed
  174. Obokata M, Reddy YNV, Melenovsky V, Sorimachi H, Jarolim P, Borlaug BA. Uncoupling between intravascular and distending pressures leads to underestimation of circulatory congestion in obesity. Eur J Heart Fail. 2022 Feb; 24 (2):353-361 Epub 2021 Nov 21
    View PubMed
  175. Deis T, Wolsk E, Mujkanovic J, Komtebedde J, Burkhoff D, Kaye D, Hasenfuss G, Hayward C, Van der Heyden J, Petrie MC, Shah SJ, Borlaug BA, Kahwash R, Litwin S, Hoendermis E, Hummel S, Gustafsson F. Resting and exercise haemodynamic characteristics of patients with advanced heart failure and preserved ejection fraction. ESC Heart Fail. 2022 Feb; 9 (1):186-195 Epub 2021 Dec 08
    View PubMed
  176. Omote K, Verbrugge FH, Borlaug BA. Heart Failure with Preserved Ejection Fraction: Mechanisms and Treatment Strategies. Annu Rev Med. 2022 Jan 27; 73:321-337 Epub 2021 Aug 11
    View PubMed
  177. Verbrugge FH, Reddy YNV, Attia ZI, Friedman PA, Noseworthy PA, Lopez-Jimenez F, Kapa S, Borlaug BA. Detection of Left Atrial Myopathy Using Artificial Intelligence-Enabled Electrocardiography. Circ Heart Fail. 2022 Jan; 15 (1):e008176 Epub 2021 Dec 16
    View PubMed
  178. Koepp KE, Reddy YNV, Obokata M, Sorimachi H, Verbrugge FH, Jain CC, Egbe AC, Redfield MM, Olson TP, Borlaug BA. Identification of Patients with Preclinical Heart Failure with preserved Ejection Fraction Using the H(2)FPEF Score. Nat Cardiovasc Res. 2022 Jan; 1 (1):59-66 Epub 2022 Jan 12
    View PubMed
  179. Harada T, Obokata M, Omote K, Iwano H, Ikoma T, Okada K, Yoshida K, Kato T, Kurosawa K, Nagai T, Anzai T, Borlaug BA, Kurabayashi M. Functional Tricuspid Regurgitation and Right Atrial Remodeling in Heart Failure With Preserved Ejection Fraction. Am J Cardiol. 2022 Jan 1; 162:129-135 Epub 2021 Oct 24
    View PubMed
  180. Hsu S, Fang JC, Borlaug BA. Hemodynamics for the Heart Failure Clinician: A State-of-the-Art Review. J Card Fail. 2022 Jan; 28 (1):133-148 Epub 2021 Aug 10
    View PubMed
  181. Pugliese NR, De Biase N, Gargani L, Mazzola M, Conte L, Fabiani I, Natali A, Dini FL, Frumento P, Rosada J, Taddei S, Borlaug BA, Masi S. Predicting the transition to and progression of heart failure with preserved ejection fraction: a weighted risk score using bio-humoural, cardiopulmonary, and echocardiographic stress testing. Eur J Prev Cardiol. 2021 Dec 29; 28 (15):1650-1661
    View PubMed
  182. Jentzer JC, Wiley BM, Gersh BJ, Borlaug BA, Oh JK, Anavekar NS. Myocardial contraction fraction by echocardiography and mortality in cardiac intensive care unit patients. Int J Cardiol. 2021 Dec 1; 344:230-239 Epub 2021 Sept 23
    View PubMed
  183. Obokata M, Reddy YNV, Koepp KE, Stewart GM, Olson TP, Melenovsky V, Burkhoff D, Borlaug BA. Salutary Acute Effects of Exercise on Central Hemodynamics in Heart Failure With Preserved Ejection Fraction. J Card Fail. 2021 Dec; 27 (12):1313-1320 Epub 2021 May 08
    View PubMed
  184. Redfield MM, Borlaug BA. Quality of Life and Exercise Ability in Heart Failure With Preserved Ejection Fraction: No Time for Therapeutic Complacency. JAMA 2021 Nov 16; 326 (19):1913-1915
    View PubMed
  185. Omar M, Jensen J, Frederiksen PH, Videbaek L, Poulsen MK, Brond JC, Gustafsson F, Borlaug BA, Schou M, Moller JE. Hemodynamic Determinants of Activity Measured by Accelerometer in Patients With Stable Heart Failure. JACC Heart Fail. 2021 Nov; 9 (11):824-835 Epub 2021 Sept 08
    View PubMed
  186. Nassif ME, Windsor SL, Borlaug BA, Kitzman DW, Shah SJ, Tang F, Khariton Y, Malik AO, Khumri T, Umpierrez G, Lamba S, Sharma K, Khan SS, Chandra L, Gordon RA, Ryan JJ, Chaudhry SP, Joseph SM, Chow CH, Kanwar MK, Pursley M, Siraj ES, Lewis GD, Clemson BS, Fong M, Kosiborod MN. The SGLT2 inhibitor dapagliflozin in heart failure with preserved ejection fraction: a multicenter randomized trial. Nat Med. 2021 Nov; 27 (11):1954-1960 Epub 2021 Oct 28
    View PubMed
  187. Egbe AC, Miranda WR, Connolly HM, Borlaug BA. Coarctation of aorta is associated with left ventricular stiffness, left atrial dysfunction and pulmonary hypertension. Am Heart J. 2021 Nov; 241:50-58 Epub 2021 July 18
    View PubMed
  188. Pugliese NR, Paneni F, Mazzola M, De Biase N, Del Punta L, Gargani L, Mengozzi A, Virdis A, Nesti L, Taddei S, Flammer A, Borlaug BA, Ruschitzka F, Masi S. Impact of epicardial adipose tissue on cardiovascular haemodynamics, metabolic profile, and prognosis in heart failure. Eur J Heart Fail. 2021 Nov; 23 (11):1858-1871 Epub 2021 Sept 05
    View PubMed
  189. AbouEzzeddine OF, Davies DR, Scott CG, Fayyaz AU, Askew JW, McKie PM, Noseworthy PA, Johnson GB, Dunlay SM, Borlaug BA, Chareonthaitawee P, Roger VL, Dispenzieri A, Grogan M, Redfield MM. Prevalence of Transthyretin Amyloid Cardiomyopathy in Heart Failure With Preserved Ejection Fraction. JAMA Cardiol. 2021 Nov 1; 6 (11):1267-1274
    View PubMed
  190. Verbrugge FH, Reddy YNV, Eleid MF, Lin G, Burkhoff D, Borlaug BA. Mild aortic valve disease and the diastolic pressure-volume relationship in heart failure with preserved ejection fraction. Open Heart. 2021 Oct; 8 (2)
    View PubMed
  191. Sorimachi H, Burkhoff D, Verbrugge FH, Omote K, Obokata M, Reddy YNV, Takahashi N, Sunagawa K, Borlaug BA. Obesity, venous capacitance, and venous compliance in heart failure with preserved ejection fraction. Eur J Heart Fail. 2021 Oct; 23 (10):1648-1658 Epub 2021 June 17
    View PubMed
  192. Pandey A, Shah SJ, Butler J, Kellogg DL Jr, Lewis GD, Forman DE, Mentz RJ, Borlaug BA, Simon MA, Chirinos JA, Fielding RA, Volpi E, Molina AJA, Haykowsky MJ, Sam F, Goodpaster BH, Bertoni AG, Justice JN, White JP, Ding J, Hummel SL, LeBrasseur NK, Taffet GE, Pipinos II, Kitzman D. Exercise Intolerance in Older Adults With Heart Failure With Preserved Ejection Fraction: JACC State-of-the-Art Review. J Am Coll Cardiol. 2021 Sep 14; 78 (11):1166-1187
    View PubMed
  193. Brener MI, Hamid NB, Sunagawa K, Borlaug BA, Shah SJ, Rich S, Burkhoff D. Changes in Stressed Blood Volume with Levosimendan in Pulmonary Hypertension from Heart Failure with Preserved Ejection Fraction: Insights Regarding Mechanism of Action From the HELP Trial. J Card Fail. 2021 Sep; 27 (9):1023-1026 Epub 2021 June 16
    View PubMed
  194. Fermoyle CC, Stewart GM, Borlaug BA, Johnson BD. Simultaneous Measurement of Lung Diffusing Capacity and Pulmonary Hemodynamics Reveals Exertional Alveolar-Capillary Dysfunction in Heart Failure With Preserved Ejection Fraction. J Am Heart Assoc. 2021 Aug 17; 10 (16):e019950 Epub 2021 Aug 07
    View PubMed
  195. Sharma A, Greene S, Vaduganathan M, Fudim M, Ambrosy AP, Sun JL, McNulty SE, Hernandez AF, Borlaug BA, Velazquez EJ, Mentz RJ, DeVore AD, Alhanti B, Margulies K, Felker GM. Growth differentiation factor-15, treatment with liraglutide, and clinical outcomes among patients with heart failure. ESC Heart Fail. 2021 Aug; 8 (4):2608-2616 Epub 2021 June 01
    View PubMed
  196. Kumar V, Manduca A, Rao C, Ryu AJ, Gibbons RJ, Gersh BJ, Chandrasekaran K, Asirvatham SJ, Araoz PA, Oh JK, Egbe AC, Behfar A, Borlaug BA, Anavekar NS. An under-recognized phenomenon: Myocardial volume change during the cardiac cycle. Echocardiography. 2021 Aug; 38 (8):1235-1244 Epub 2021 June 04
    View PubMed
  197. Ezzeddine FM, Giudicessi JR, Maleszewski JJ, Lin PT, Borlaug BA, Geske JB. Unmasking Hydroxychloroquine Cardiotoxicity in a Patient With Heart Failure and Chronotropic Incompetence. JACC Case Rep. 2021 Jul 7; 3 (7):997-1001 Epub 2021 May 26
    View PubMed
  198. Sorimachi H, Omote K, Borlaug BA. Clinical Phenogroups in Heart Failure with Preserved Ejection Fraction. Heart Fail Clin. 2021 Jul; 17 (3):483-498
    View PubMed
  199. Miller WL, Sorimachi H, Grill DE, Fischer K, Borlaug BA. Contributions of cardiac dysfunction and volume status to central haemodynamics in chronic heart failure. Eur J Heart Fail. 2021 Jul; 23 (7):1097-1105 Epub 2021 Feb 21
    View PubMed
  200. Anand V, Bradley D, Frye RL, Borlaug BA. Things Are Not Always as They Seem: Multimodality Exercise Assessment in the Evaluation of Dyspnea. Circulation. 2021 Jun 22; 143 (25):2502-2507 Epub 2021 June 21
    View PubMed
  201. Verbrugge FH, Reddy YNV, Sorimachi H, Omote K, Carter RE, Borlaug BA. Diagnostic scores predict morbidity and mortality in patients hospitalized for heart failure with preserved ejection fraction. Eur J Heart Fail. 2021 Jun; 23 (6):954-963 Epub 2021 Mar 09
    View PubMed
  202. Sun D, Schaff HV, Gersh BJ, Borlaug BA. Nonobstructive Hypertrophic Cardiomyopathy in a Patient With Mitral Prosthesis. Ann Thorac Surg. 2021 Jun; 111 (6):e429-e432 Epub 2020 Dec 08
    View PubMed
  203. Reddy YNV, Stewart GM, Obokata M, Koepp KE, Borlaug BA. Peripheral and pulmonary effects of inorganic nitrite during exercise in heart failure with preserved ejection fraction. Eur J Heart Fail. 2021 May; 23 (5):814-823 Epub 2021 Feb 01
    View PubMed
  204. Wolsk E, Kaye DM, Komtebedde J, Shah SJ, Borlaug BA, Burkhoff D, Kitzman DW, Cleland JG, Hasenfuss G, Hassager C, Moller JE, Gustafsson F. Determinants and consequences of heart rate and stroke volume response to exercise in patients with heart failure and preserved ejection fraction. Eur J Heart Fail. 2021 May; 23 (5):754-764 Epub 2021 Mar 22
    View PubMed
  205. Burkhoff D, Borlaug BA, Shah SJ, Zolty R, Tedford RJ, Thenappan T, Zamanian RT, Mazurek JA, Rich JD, Simon MA, Chung ES, Raza F, Majure DT, Lewis GD, Preston IR, Rich S. Levosimendan Improves Hemodynamics and Exercise Tolerance in PH-HFpEF: Results of the Randomized Placebo-Controlled HELP Trial. JACC Heart Fail. 2021 May; 9 (5):360-370 Epub 2021 Apr 07
    View PubMed
  206. Rethy L, Borlaug BA, Redfield MM, Oh JK, Shah SJ, Patel RB. Application of Guideline-Based Echocardiographic Assessment of Left Atrial Pressure to Heart Failure with Preserved Ejection Fraction. J Am Soc Echocardiogr. 2021 May; 34 (5):455-464 Epub 2021 Jan 21
    View PubMed
  207. Ahmad A, Corban MT, Toya T, Verbrugge FH, Sara JD, Lerman LO, Borlaug BA, Lerman A. Coronary microvascular dysfunction is associated with exertional haemodynamic abnormalities in patients with heart failure with preserved ejection fraction. Eur J Heart Fail. 2021 May; 23 (5):765-772 Epub 2020 Oct 07
    View PubMed
  208. Sorimachi H, Obokata M, Takahashi N, Reddy YNV, Jain CC, Verbrugge FH, Koepp KE, Khosla S, Jensen MD, Borlaug BA. Pathophysiologic importance of visceral adipose tissue in women with heart failure and preserved ejection fraction. Eur Heart J. 2021 Apr 21; 42 (16):1595-1605
    View PubMed
  209. Jentzer JC, Anavekar NS, Reddy YNV, Murphree DH, Wiley BM, Oh JK, Borlaug BA. Right Ventricular Pulmonary Artery Coupling and Mortality in Cardiac Intensive Care Unit Patients. J Am Heart Assoc. 2021 Apr 6; 10 (7):e019015 Epub 2021 Mar 28
    View PubMed
  210. Ng ACT, Delgado V, Borlaug BA, Bax JJ. Diabesity: the combined burden of obesity and diabetes on heart disease and the role of imaging. Nat Rev Cardiol. 2021 Apr; 18 (4):291-304 Epub 2020 Nov 13
    View PubMed
  211. Fudim M, Patel MR, Boortz-Marx R, Borlaug BA, DeVore AD, Ganesh A, Green CL, Lopes RD, Mentz RJ, Patel CB, Rogers JG, Felker GM, Hernandez AF, Sunagawa K, Burkhoff D. Splanchnic Nerve Block Mediated Changes in Stressed Blood Volume in Heart Failure. JACC Heart Fail. 2021 Apr; 9 (4):293-300 Epub 2021 Mar 10
    View PubMed
  212. Reddy YNV, Borlaug BA. Pulmonary Hypertension in Left Heart Disease. Clin Chest Med. 2021 Mar; 42 (1):39-58
    View PubMed
  213. Guazzi M, Borlaug B, Metra M, Losito M, Bandera F, Alfonzetti E, Boveri S, Sugimoto T. Revisiting and Implementing the Weber and Ventilatory Functional Classifications in Heart Failure by Cardiopulmonary Imaging Phenotyping. J Am Heart Assoc. 2021 Feb; 10 (5):e018822 Epub 2021 Feb 20
    View PubMed
  214. Monzo L, Reichenbach A, Al-Hiti H, Borlaug BA, Havlenova T, Solar N, Tupy M, Ters J, Kautzner J, Melenovsky V. Acute Unloading Effects of Sildenafil Enhance Right Ventricular-Pulmonary Artery Coupling in Heart Failure. J Card Fail. 2021 Feb; 27 (2):224-232 Epub 2020 Nov 21
    View PubMed
  215. Monzo L, Sedlacek K, Hromanikova K, Tomanova L, Borlaug BA, Jabor A, Kautzner J, Melenovsky V. Myocardial ketone body utilization in patients with heart failure: The impact of oral ketone ester. Metabolism. 2021 Feb; 115:154452 Epub 2020 Nov 26
    View PubMed
  216. D'Alto M, Badesch D, Bossone E, Borlaug BA, Brittain E, Humbert M, Naeije R. A Fluid Challenge Test for the Diagnosis of Occult Heart Failure. Chest. 2021 Feb; 159 (2):791-797 Epub 2020 Aug 14
    View PubMed
  217. Jain CC, Pedrotty D, Araoz PA, Sugrue A, Vaidya VR, Padmanabhan D, Arunachalam SP, Lerman LO, Asirvatham SJ, Borlaug BA. Sustained Improvement in Diastolic Reserve Following Percutaneous Pericardiotomy in a Porcine Model of Heart Failure With Preserved Ejection Fraction. Circ Heart Fail. 2021 Feb; 14 (2):e007530 Epub 2021 Jan 22
    View PubMed
  218. Fudim M, Ashur N, Jones AD, Ambrosy AP, Bart BA, Butler J, Chen HH, Greene SJ, Reddy Y, Redfield MM, Sharma A, Hernandez AF, Felker GM, Borlaug BA, Mentz RJ. Implications of peripheral oedema in heart failure with preserved ejection fraction: a heart failure network analysis. ESC Heart Fail. 2021 Feb; 8 (1):662-669 Epub 2020 Dec 09
    View PubMed
  219. Egbe AC, Vojjini R, Badawy M, Jain V, Bonnichsen CR, Reddy YNV, Obokata M, Borlaug BA. Heightened Dependence of Left-Heart Filling Pressures on Right-Heart Failure in Congenital Heart Disease. Can J Cardiol. 2021 Jan; 37 (1):131-139 Epub 2020 Feb 26
    View PubMed
  220. Kumar V, Ryu AJ, Manduca A, Rao C, Gibbons RJ, Gersh BJ, Chandrasekaran K, Asirvatham SJ, Araoz PA, Oh JK, Egbe AC, Behfar A, Borlaug BA, Anavekar NS. Cardiac MRI demonstrates compressibility in healthy myocardium but not in myocardium with reduced ejection fraction. Int J Cardiol. 2021 Jan 1; 322:278-283 Epub 2020 Aug 29
    View PubMed
  221. Pugliese NR, De Biase N, Conte L, Gargani L, Mazzola M, Fabiani I, Natali A, Dini FL, Frumento P, Rosada J, Taddei S, Borlaug BA, Masi S. Cardiac Reserve and Exercise Capacity: Insights from Combined Cardiopulmonary and Exercise Echocardiography Stress Testing. J Am Soc Echocardiogr. 2021 Jan; 34 (1):38-50 Epub 2020 Oct 06
    View PubMed
  222. Ryu AJ, Kumar V, Borlaug BA, Manduca A, Rao CK, Gibbons RJ, Asirvatham SJ, Gersh BJ, Chandrasekaran K, Araoz PA, Oh JK, Egbe AC, Behfar A, Anavekar NS. Systolic-to-diastolic myocardial volume ratio as a novel imaging marker of cardiomyopathy. Int J Cardiol. 2021 Jan 1; 322:272-277 Epub 2020 Aug 12
    View PubMed
  223. Omar M, Jensen J, Frederiksen PH, Kistorp C, Videbaek L, Poulsen MK, Moller S, Ali M, Gustafsson F, Kober L, Borlaug BA, Schou M, Moller JE. Effect of Empagliflozin on Hemodynamics in Patients With Heart Failure and Reduced Ejection Fraction. J Am Coll Cardiol. 2020 Dec 8; 76 (23):2740-2751
    View PubMed
  224. Egbe AC, Miranda WR, Anderson JH, Borlaug BA. Hemodynamic and Clinical Implications of Impaired Pulmonary Vascular Reserve in the Fontan Circulation. J Am Coll Cardiol. 2020 Dec 8; 76 (23):2755-2763
    View PubMed
  225. Smith JR, Joyner MJ, Curry TB, Borlaug BA, Keller-Ross ML, Van Iterson EH, Olson TP. Locomotor muscle group III/IV afferents constrain stroke volume and contribute to exercise intolerance in human heart failure. J Physiol. 2020 Dec; 598 (23):5379-5390 Epub 2020 Sept 23
    View PubMed
  226. Jain CC, Borlaug BA. Performance and Interpretation of Invasive Hemodynamic Exercise Testing. Chest. 2020 Nov; 158 (5):2119-2129 Epub 2020 May 28
    View PubMed
  227. Jentzer JC, Anavekar NS, Burstein BJ, Borlaug BA, Oh JK. Noninvasive Echocardiographic Left Ventricular Stroke Work Index Predicts Mortality in Cardiac Intensive Care Unit Patients. Circ Cardiovasc Imaging. 2020 Nov; 13 (11):e011642 Epub 2020 Nov 16
    View PubMed
  228. Fermoyle CC, Stewart GM, Borlaug BA, Johnson BD. Effects of exercise on thoracic blood volumes, lung fluid accumulation, and pulmonary diffusing capacity in heart failure with preserved ejection fraction. Am J Physiol Regul Integr Comp Physiol. 2020 Nov 1; 319 (5):R602-R609 Epub 2020 Sept 16
    View PubMed
  229. Fermoyle CC, Stewart GM, Borlaug BA, Johnson BD. Pulmonary Vascular Pressures and Gas Exchange Response to Exercise in Heart Failure With Preserved Ejection Fraction. J Card Fail. 2020 Nov; 26 (11):1011-1015 Epub 2020 Aug 01
    View PubMed
  230. Reddy YNV, Obokata M, Jones AD, Lewis GD, Shah SJ, Abouezzedine OF, Fudim M, Alhanti B, Stevenson LW, Redfield MM, Borlaug BA. Characterization of the Progression From Ambulatory to Hospitalized Heart Failure With Preserved Ejection Fraction. J Card Fail. 2020 Nov; 26 (11):919-928 Epub 2020 Aug 19
    View PubMed
  231. Egbe AC, Connolly HM, Miranda WR, Scott CG, Borlaug BA. Prognostic implications of inferior vena cava haemodynamics in ambulatory patients with tetralogy of Fallot. ESC Heart Fail. 2020 Oct; 7 (5):2589-2596 Epub 2020 June 26
    View PubMed
  232. Jain CC, Egbe AC, Borlaug BA. Every Now and Then I Fall Apart: Total Eclipse of the Mitral Valve. Circ Heart Fail 2020 Oct; 13 (10):e007145 Epub 2020 Sept 08
    View PubMed
  233. Taher R, Sara JD, Toya T, Borlaug BA, Lerman LO, Lerman A. Peripheral endothelial dysfunction is a novel risk factor for systolic dysfunction and heart failure progression. Int J Cardiol Heart Vasc. 2020 Oct; 30:100584 Epub 2020 July 23
    View PubMed
  234. Borlaug BA, Maleszewski JJ. The heavy heart of HFpEF. Eur Heart J. 2020 Sep 21; 41 (36):3447
    View PubMed
  235. Verbrugge FH, Guazzi M, Testani JM, Borlaug BA. Altered Hemodynamics and End-Organ Damage in Heart Failure: Impact on the Lung and Kidney. Circulation. 2020 Sep 8; 142 (10):998-1012 Epub 2020 Sept 08
    View PubMed
  236. Packer M, Lam CSP, Lund LH, Maurer MS, Borlaug BA. Characterization of the inflammatory-metabolic phenotype of heart failure with a preserved ejection fraction: a hypothesis to explain influence of sex on the evolution and potential treatment of the disease. Eur J Heart Fail. 2020 Sep; 22 (9):1551-1567 Epub 2020 June 26
    View PubMed
  237. Borlaug BA. Evaluation and management of heart failure with preserved ejection fraction. Nat Rev Cardiol. 2020 Sep; 17 (9):559-573 Epub 2020 Mar 30
    View PubMed
  238. Stewart GM, Johnson BD, Sprecher DL, Reddy YNV, Obokata M, Goldsmith S, Bart B, Oughton A, Fillmore C, Behm DJ, Borlaug BA. Targeting pulmonary capillary permeability to reduce lung congestion in heart failure: a randomized, controlled pilot trial. Eur J Heart Fail. 2020 Sep; 22 (9):1641-1645 Epub 2020 Mar 30
    View PubMed
  239. Del Buono MG, Iannaccone G, Scacciavillani R, Carbone S, Camilli M, Niccoli G, Borlaug BA, Lavie CJ, Arena R, Crea F, Abbate A. Heart failure with preserved ejection fraction diagnosis and treatment: An updated review of the evidence. Prog Cardiovasc Dis. 2020 Sep - Oct; 63 (5):570-584 Epub 2020 May 05
    View PubMed
  240. Reddy YNV, Obokata M, Verbrugge FH, Lin G, Borlaug BA. Atrial Dysfunction in Patients With Heart Failure With Preserved Ejection Fraction and Atrial Fibrillation. J Am Coll Cardiol. 2020 Sep 1; 76 (9):1051-1064
    View PubMed
  241. Griffin JM, Borlaug BA, Komtebedde J, Litwin SE, Shah SJ, Kaye DM, Hoendermis E, Hasenfuss G, Gustafsson F, Wolsk E, Uriel N, Burkhoff D. Impact of Interatrial Shunts on Invasive Hemodynamics and Exercise Tolerance in Patients With Heart Failure. J Am Heart Assoc. 2020 Sep; 9 (17):e016760 Epub 2020 Aug 15
    View PubMed
  242. Selvaraj S, Myhre PL, Vaduganathan M, Claggett BL, Matsushita K, Kitzman DW, Borlaug BA, Shah AM, Solomon SD. Application of Diagnostic Algorithms for Heart Failure With Preserved Ejection Fraction to the Community. JACC Heart Fail. 2020 Aug; 8 (8):640-653 Epub 2020 June 10
    View PubMed
  243. Ezzeddine FM, Mulpuru SK, Borlaug BA. A Tough Time Running Around the Block. Circ Heart Fail. 2020 Aug; 13 (8):e007182 Epub 2020 July 15
    View PubMed
  244. Koepp KE, Obokata M, Reddy YNV, Olson TP, Borlaug BA. Hemodynamic and Functional Impact of Epicardial Adipose Tissue in Heart Failure With Preserved Ejection Fraction. JACC Heart Fail. 2020 Aug; 8 (8):657-666 Epub 2020 July 08
    View PubMed
  245. Sabbah MS, Fayyaz AU, de Denus S, Felker GM, Borlaug BA, Dasari S, Carter RE, Redfield MM. Obese-Inflammatory Phenotypes in Heart Failure With Preserved Ejection Fraction. Circ Heart Fail. 2020 Aug; 13 (8):e006414 Epub 2020 July 29
    View PubMed
  246. Guazzi M, Generati G, Borlaug B, Alfonzetti E, Sugimoto T, Castelvecchio S, Menicanti L, Bandera F. Redistribution of cardiac output during exercise by functional mitral regurgitation in heart failure: compensatory O2 peripheral uptake to delivery failure. Am J Physiol Heart Circ Physiol. 2020 Jul 1; 319 (1):H100-H108 Epub 2020 May 22
    View PubMed
  247. Reddy YNV, Rikhi A, Obokata M, Shah SJ, Lewis GD, AbouEzzedine OF, Dunlay S, McNulty S, Chakraborty H, Stevenson LW, Redfield MM, Borlaug BA. Quality of life in heart failure with preserved ejection fraction: importance of obesity, functional capacity, and physical inactivity. Eur J Heart Fail. 2020 Jun; 22 (6):1009-1018 Epub 2020 Mar 09
    View PubMed
  248. Reddy YNV, Borlaug BA, O'Connor CM, Gersh BJ. Novel approaches to the management of chronic systolic heart failure: future directions and unanswered questions. Eur Heart J. 2020 May 7; 41 (18):1764-1774
    View PubMed
  249. Egbe AC, Pellikka PA, Miranda WR, Bonnichsen C, Reddy YNV, Borlaug BA, Connolly HM. Echocardiographic predictors of severe right ventricular diastolic dysfunction in tetralogy of Fallot: Relations to patient outcomes. Int J Cardiol. 2020 May 1; 306:49-55 Epub 2020 Feb 27
    View PubMed
  250. Redouane B, Greene SJ, Fudim M, Vaduganathan M, Ambrosy AP, Sun JL, DeVore AD, McNulty SE, Mentz RJ, Hernandez AF, Felker GM, Cooper LB, Borlaug BA, Velazquez EJ, Margulies KB, Sharma A. Effects of Liraglutide on Worsening Renal Function Among Patients With Heart Failure With Reduced Ejection Fraction: Insights From the FIGHT Trial. Circ Heart Fail. 2020 May; 13 (5):e006758 Epub 2020 May 04
    View PubMed
  251. Guglin M, Zucker MJ, Borlaug BA, Breen E, Cleveland J, Johnson MR, Panjrath GS, Patel JK, Starling RC, Bozkurt B, ACC Heart Failure and Transplant Member Section and Leadership Council. Evaluation for Heart Transplantation and LVAD Implantation: JACC Council Perspectives. J Am Coll Cardiol. 2020 Mar 31; 75 (12):1471-1487
    View PubMed
  252. Shah SJ, Borlaug BA, Kitzman DW, McCulloch AD, Blaxall BC, Agarwal R, Chirinos JA, Collins S, Deo RC, Gladwin MT, Granzier H, Hummel SL, Kass DA, Redfield MM, Sam F, Wang TJ, Desvigne-Nickens P, Adhikari BB. Research Priorities for Heart Failure With Preserved Ejection Fraction: National Heart, Lung, and Blood Institute Working Group Summary. Circulation. 2020 Mar 24; 141 (12):1001-1026 Epub 2020 Mar 23
    View PubMed
  253. Miranda WR, Hagler DJ, Taggart NW, Borlaug BA, Connolly HM, Egbe AC. Elevated ventricular filling pressures and long-term survival in adults post-Fontan. Catheter Cardiovasc Interv. 2020 Mar 1; 95 (4):803-809 Epub 2019 May 30
    View PubMed
  254. Tamargo M, Obokata M, Reddy YNV, Pislaru SV, Lin G, Egbe AC, Nishimura RA, Borlaug BA. Functional mitral regurgitation and left atrial myopathy in heart failure with preserved ejection fraction. Eur J Heart Fail. 2020 Mar; 22 (3):489-498 Epub 2020 Jan 07
    View PubMed
  255. Patel RB, Mehta R, Redfield MM, Borlaug BA, Hernandez AF, Shah SJ, Dubin RF. Renal Dysfunction in Heart Failure With Preserved Ejection Fraction: Insights From the RELAX Trial. J Card Fail. 2020 Mar; 26 (3):233-242 Epub 2020 Jan 11
    View PubMed
  256. Yang JH, Obokata M, Reddy YNV, Redfield MM, Lerman A, Borlaug BA. Endothelium-dependent and independent coronary microvascular dysfunction in patients with heart failure with preserved ejection fraction. Eur J Heart Fail. 2020 Mar; 22 (3):432-441 Epub 2019 Dec 15
    View PubMed
  257. Tang WHW, Wilcox JD, Jacob MS, Rosenzweig EB, Borlaug BA, Frantz RP, Hassoun PM, Hemnes AR, Hill NS, Horn EM, Singh HS, Systrom DM, Tedford RJ, Vanderpool RR, Waxman AB, Xiao L, Leopold JA, Rischard FP. Comprehensive Diagnostic Evaluation of Cardiovascular Physiology in Patients With Pulmonary Vascular Disease: Insights From the PVDOMICS Program. Circ Heart Fail. 2020 Mar; 13 (3):e006363 Epub 2020 Feb 24
    View PubMed
  258. Jain CC, Borlaug BA. Hemodynamic assessment in heart failure. Catheter Cardiovasc Interv. 2020 Feb 15; 95 (3):420-428 Epub 2019 Sept 10
    View PubMed
  259. Obokata M, Kane GC, Sorimachi H, Reddy YNV, Olson TP, Egbe AC, Melenovsky V, Borlaug BA. Noninvasive evaluation of pulmonary artery pressure during exercise: the importance of right atrial hypertension. Eur Respir J. 2020 Feb; 55 (2) Epub 2020 Feb 12
    View PubMed
  260. Egbe AC, Reddy YNV, Obokata M, Borlaug BA. Doppler-Derived Arterial Load Indices Better Reflect Left Ventricular Afterload Than Systolic Blood Pressure in Coarctation of Aorta. Circ Cardiovasc Imaging. 2020 Feb; 13 (2):e009672 Epub 2020 Feb 13
    View PubMed
  261. Miller WL, Borlaug BA. Impact of Obesity on Volume Status in Patients With Ambulatory Chronic Heart Failure. J Card Fail. 2020 Feb; 26 (2):112-117 Epub 2019 Sept 27
    View PubMed
  262. Reddy YNV, Obokata M, Testani JM, Felker GM, Tang WHW, Abou-Ezzeddine OF, Sun JL, Chakrabothy H, McNulty S, Shah SJ, Lewis GD, Stevenson LW, Redfield MM, Borlaug BA. Adverse Renal Response to Decongestion in the Obese Phenotype of Heart Failure With Preserved Ejection Fraction. J Card Fail. 2020 Feb; 26 (2):101-107 Epub 2019 Oct 13
    View PubMed
  263. Obokata M, Reddy YNV, Borlaug BA. Diastolic Dysfunction and Heart Failure With Preserved Ejection Fraction: Understanding Mechanisms by Using Noninvasive Methods. JACC Cardiovasc Imaging. 2020 Jan; 13 (1 Pt 2):245-257 Epub 2019 June 12
    View PubMed
  264. Sara JDS, Maor E, Borlaug B, Lewis BR, Orbelo D, Lerman LO, Lerman A. Non-invasive vocal biomarker is associated with pulmonary hypertension. PLoS One. 2020; 15 (4):e0231441 Epub 2020 Apr 16
    View PubMed
  265. Hanff TC, Kaye DM, Hayward CS, Post MC, Malek F, Hasenfubeta G, Gustafsson F, Burkhoff D, Shah SJ, Litwin SE, Kahwash R, Hummel SL, Borlaug BA, Solomon SD, Lam CSP, Komtebedde J, Silvestry FE, REDUCE LAP-HF study investigators, and research staff. Assessment of Predictors of Left Atrial Volume Response to a Transcatheter InterAtrial Shunt Device (from the REDUCE LAP-HF Trial). Am J Cardiol. 2019 Dec 15; 124 (12):1912-1917 Epub 2019 Sept 26
    View PubMed
  266. Obokata M, Kane GC, Reddy YNV, Melenovsky V, Olson TP, Jarolim P, Borlaug BA. The neurohormonal basis of pulmonary hypertension in heart failure with preserved ejection fraction. Eur Heart J. 2019 Dec 1; 40 (45):3707-3717
    View PubMed
  267. Reddy YNV, Obokata M, Wiley B, Koepp KE, Jorgenson CC, Egbe A, Melenovsky V, Carter RE, Borlaug BA. The haemodynamic basis of lung congestion during exercise in heart failure with preserved ejection fraction. Eur Heart J. 2019 Dec 1; 40 (45):3721-3730
    View PubMed
  268. Egbe AC, Taggart NW, Reddy YNV, Sufian M, Banala K, Vojjini R, Najam M, Osman K, Obokata M, Borlaug BA. Assessment and Implications of Right Ventricular Afterload in Tetralogy of Fallot. Am J Cardiol. 2019 Dec 1; 124 (11):1780-1784 Epub 2019 Sept 09
    View PubMed
  269. Obokata M, Reddy YNV, Shah SJ, Kaye DM, Gustafsson F, Hasenfubeta G, Hoendermis E, Litwin SE, Komtebedde J, Lam C, Burkhoff D, Borlaug BA. Effects of Interatrial Shunt on Pulmonary Vascular Function in Heart Failure With Preserved Ejection Fraction. J Am Coll Cardiol. 2019 Nov 26; 74 (21):2539-2550
    View PubMed
  270. Egbe AC, Bonnichsen C, Reddy YNV, Anderson JH, Borlaug BA. Pathophysiologic and Prognostic Implications of Right Atrial Hypertension in Adults With Tetralogy of Fallot. J Am Heart Assoc. 2019 Nov 19; 8 (22):e014148 Epub 2019 Nov 08
    View PubMed
  271. Borlaug , BA. Management and prevention of heart failure in dialysis patients: Specific measures UpToDate. 2019.
  272. Eleid MF, Padang R, Pislaru SV, Greason KL, Crestanello J, Nkomo VT, Pellikka PA, Jentzer JC, Gulati R, Sandhu GS, Holmes DR Jr, Nishimura RA, Rihal CS, Borlaug BA. Effect of Transcatheter Aortic Valve Replacement on Right Ventricular-Pulmonary Artery Coupling. JACC Cardiovasc Interv. 2019 Nov 11; 12 (21):2145-2154
    View PubMed
  273. AbouEzzeddine OF, Kemp BJ, Borlaug BA, Mullan BP, Behfar A, Pislaru SV, Fudim M, Redfield MM, Chareonthaitawee P. Myocardial Energetics in Heart Failure With Preserved Ejection Fraction. Circ Heart Fail. 2019 Oct; 12 (10):e006240 Epub 2019 Oct 15
    View PubMed
  274. Egbe AC, Kothapalli S, Borlaug BA, Ammash NM, Najam M, Bajwa N, Tarek K, Mathew J, Connolly HM. Mechanism and Risk Factors for Death in Adults With Tetralogy of Fallot. Am J Cardiol. 2019 Sep 1; 124 (5):803-807 Epub 2019 June 07
    View PubMed
  275. Reddy YNV, Anantha-Narayanan M, Obokata M, Koepp KE, Erwin P, Carter RE, Borlaug BA. Hemodynamic Effects of Weight Loss in Obesity: A Systematic Review and Meta-Analysis. JACC Heart Fail. 2019 Aug; 7 (8):678-687 Epub 2019 July 10
    View PubMed
  276. Yang JH, Miranda WR, Borlaug BA, Nishimura RA, Schaff HV, Greason KL, Maleszewski JJ, Oh JK. Right Atrial/Pulmonary Arterial Wedge Pressure Ratio in Primary and Mixed Constrictive Pericarditis. J Am Coll Cardiol. 2019 Jul 2; 73 (25):3312-3321
    View PubMed
  277. Reddy YNV, Obokata M, Egbe A, Yang JH, Pislaru S, Lin G, Carter R, Borlaug BA. Left atrial strain and compliance in the diagnostic evaluation of heart failure with preserved ejection fraction. Eur J Heart Fail. 2019 Jul; 21 (7):891-900 Epub 2019 Mar 28
    View PubMed
  278. Egbe AC, Miranda WR, Pellikka PA, Pislaru SV, Borlaug BA, Kothapalli S, Ananthaneni S, Sandhyavenu H, Najam M, Farouk Abdelsamid M, Connolly HM. Right ventricular and pulmonary vascular function indices for risk stratification of patients with pulmonary regurgitation. Congenit Heart Dis. 2019 Jul; 14 (4):657-664 Epub 2019 Apr 08
    View PubMed
  279. Reddy YNV, Lewis GD, Shah SJ, Obokata M, Abou-Ezzedine OF, Fudim M, Sun JL, Chakraborty H, McNulty S, LeWinter MM, Mann DL, Stevenson LW, Redfield MM, Borlaug BA. Characterization of the Obese Phenotype of Heart Failure With Preserved Ejection Fraction: A RELAX Trial Ancillary Study. Mayo Clin Proc. 2019 Jul; 94 (7):1199-1209
    View PubMed
  280. Borlaug BA, Reddy YNV. The Role of the Pericardium in Heart Failure: Implications for Pathophysiology and Treatment. JACC Heart Fail. 2019 Jul; 7 (7):574-585
    View PubMed
  281. Egbe AC, Kothapalli S, Miranda WR, Pislaru S, Ammash NM, Borlaug BA, Pellikka PA, Najam M, Connolly HM. Assessment of Right Ventricular-Pulmonary Arterial Coupling in Chronic Pulmonary Regurgitation. Can J Cardiol. 2019 Jul; 35 (7):914-922 Epub 2019 Mar 18
    View PubMed
  282. Miranda WR, Borlaug BA, Hagler DJ, Connolly HM, Egbe AC. Haemodynamic profiles in adult Fontan patients: associated haemodynamics and prognosis. Eur J Heart Fail. 2019 Jun; 21 (6):803-809 Epub 2019 Jan 23
    View PubMed
  283. Nishimura RA, Borlaug BA. Diastology for the clinician. J Cardiol. 2019 Jun; 73 (6):445-452 Epub 2019 Mar 25
    View PubMed
  284. Pfeffer MA, Shah AM, Borlaug BA. Heart Failure With Preserved Ejection Fraction In Perspective. Circ Res. 2019 May 24; 124 (11):1598-1617
    View PubMed
  285. Del Buono MG, Arena R, Borlaug BA, Carbone S, Canada JM, Kirkman DL, Garten R, Rodriguez-Miguelez P, Guazzi M, Lavie CJ, Abbate A. Exercise Intolerance in Patients With Heart Failure: JACC State-of-the-Art Review. J Am Coll Cardiol. 2019 May 7; 73 (17):2209-2225
    View PubMed
  286. Smith JR, Borlaug BA, Olson TP. Exercise Ventilatory Efficiency in Older and Younger Heart Failure Patients With Preserved Ejection Fraction. J Card Fail. 2019 Apr; 25 (4):278-285 Epub 2019 Feb 27
    View PubMed
  287. Obokata M, Reddy YNV, Borlaug BA. The Role of Echocardiography in Heart Failure with Preserved Ejection Fraction: What Do We Want from Imaging? Heart Fail Clin. 2019 Apr; 15 (2):241-256 Epub 2019 Feb 02
    View PubMed
  288. Wolsk E, Kaye D, Komtebedde J, Shah SJ, Borlaug BA, Burkhoff D, Kitzman DW, Lam CSP, van Veldhuisen DJ, Ponikowski P, Petrie MC, Hassager C, Moller JE, Gustafsson F. Central and Peripheral Determinants of Exercise Capacity in Heart Failure Patients With Preserved Ejection Fraction. JACC Heart Fail. 2019 Apr; 7 (4):321-332 Epub 2019 Mar 06
    View PubMed
  289. El Sabbagh A, Reddy YNV, Barros-Gomes S, Borlaug BA, Miranda WR, Pislaru SV, Nishimura RA, Pellikka PA. Low-Gradient Severe Mitral Stenosis: Hemodynamic Profiles, Clinical Characteristics, and Outcomes. J Am Heart Assoc. 2019 Mar 5; 8 (5):e010736
    View PubMed
  290. Obokata M, Reddy YNV, Melenovsky V, Pislaru S, Borlaug BA. Deterioration in right ventricular structure and function over time in patients with heart failure and preserved ejection fraction. Eur Heart J. 2019 Feb 21; 40 (8):689-697
    View PubMed
  291. Reddy YNV, Obokata M, Koepp KE, Egbe AC, Wiley B, Borlaug BA. The beta-Adrenergic Agonist Albuterol Improves Pulmonary Vascular Reserve in Heart Failure With Preserved Ejection Fraction. Circ Res. 2019 Jan 18; 124 (2):306-314
    View PubMed
  292. Smith JR, Van Iterson EH, Johnson BD, Borlaug BA, Olson TP. Exercise ventilatory inefficiency in heart failure and chronic obstructive pulmonary disease. Int J Cardiol. 2019 Jan 1; 274:232-236 Epub 2018 Sept 05
    View PubMed
  293. Chignalia AZ, Isbatan A, Patel M, Ripper R, Sharlin J, Shosfy J, Borlaug BA, Dull RO. Pressure-dependent NOS activation contributes to endothelial hyperpermeability in a model of acute heart failure. Biosci Rep. 2018 Dec 21; 38 (6) Epub 2018 Nov 23
    View PubMed
  294. Fudim M, Ambrosy AP, Sun JL, Anstrom KJ, Bart BA, Butler J, AbouEzzeddine O, Greene SJ, Mentz RJ, Redfield MM, Reddy YNV, Vaduganathan M, Braunwald E, Hernandez AF, Borlaug BA, Felker GM. High-Sensitivity Troponin I in Hospitalized and Ambulatory Patients With Heart Failure With Preserved Ejection Fraction: Insights From the Heart Failure Clinical Research Network. J Am Heart Assoc. 2018 Dec 18; 7 (24):e010364
    View PubMed
  295. Egbe AC, Miranda WR, Said SM, Pislaru SV, Pellikka PA, Borlaug BA, Kothapalli S, Connolly HM. Risk stratification and clinical outcomes after surgical pulmonary valve replacement. Am Heart J. 2018 Dec; 206:105-112 Epub 2018 Sept 29
    View PubMed
  296. Sharma A, Ambrosy AP, DeVore AD, Margulies KB, McNulty SE, Mentz RJ, Hernandez AF, Michael Felker G, Cooper LB, Lala A, Vader J, Groake JD, Borlaug BA, Velazquez EJ. Liraglutide and weight loss among patients with advanced heart failure and a reduced ejection fraction: insights from the FIGHT trial. ESC Heart Fail. 2018 Dec; 5 (6):1035-1043 Epub 2018 Aug 17
    View PubMed
  297. Egbe AC, Reddy YNV, Khan AR, Al-Otaibi M, Akintoye E, Obokata M, Borlaug BA. Venous congestion and pulmonary vascular function in Fontan circulation: Implications for prognosis and treatment. Int J Cardiol. 2018 Nov 15; 271:312-316
    View PubMed
  298. Borlaug BA, Schaff HV, Pochettino A, Pedrotty DM, Asirvatham SJ, Abel MD, Carter RE, Mauermann WJ. Pericardiotomy Enhances Left Ventricular Diastolic Reserve With Volume Loading in Humans. Circulation 2018 Nov 13; 138 (20):2295-2297
    View PubMed
  299. Borlaug BA, Anstrom KJ, Lewis GD, Shah SJ, Levine JA, Koepp GA, Givertz MM, Felker GM, LeWinter MM, Mann DL, Margulies KB, Smith AL, Tang WHW, Whellan DJ, Chen HH, Davila-Roman VG, McNulty S, Desvigne-Nickens P, Hernandez AF, Braunwald E, Redfield MM, National Heart, Lung, and Blood Institute Heart Failure Clinical Research Network. Effect of Inorganic Nitrite vs Placebo on Exercise Capacity Among Patients With Heart Failure With Preserved Ejection Fraction: The INDIE-HFpEF Randomized Clinical Trial. JAMA. 2018 Nov 6; 320 (17):1764-1773
    View PubMed
  300. Melenovsky V, Hlavata K, Sedivy P, Dezortova M, Borlaug BA, Petrak J, Kautzner J, Hajek M. Skeletal Muscle Abnormalities and Iron Deficiency in Chronic Heart FailureAn Exercise (31)P Magnetic Resonance Spectroscopy Study of Calf Muscle. Circ Heart Fail. 2018 Sep; 11 (9):e004800
    View PubMed
  301. Obokata M, Reddy YNV, Yang JH, Wiley BM, Borlaug BA. Left Atrial Contracture or Failure to Dilate. Circ Heart Fail. 2018 Sep; 11 (9):e005163
    View PubMed
  302. Reddy YNV, Carter RE, Obokata M, Redfield MM, Borlaug BA. A Simple, Evidence-Based Approach to Help Guide Diagnosis of Heart Failure With Preserved Ejection Fraction. Circulation. 2018 Aug 28; 138 (9):861-870
    View PubMed
  303. Gorter TM, Obokata M, Reddy YNV, Melenovsky V, Borlaug BA. Exercise unmasks distinct pathophysiologic features in heart failure with preserved ejection fraction and pulmonary vascular disease. Eur Heart J. 2018 Aug 7; 39 (30):2825-2835
    View PubMed
  304. Obokata M, Olson TP, Reddy YNV, Melenovsky V, Kane GC, Borlaug BA. Haemodynamics, dyspnoea, and pulmonary reserve in heart failure with preserved ejection fraction. Eur Heart J. 2018 Aug 7; 39 (30):2810-2821
    View PubMed
  305. Wessler J, Kaye D, Gustafsson F, Petrie MC, Hasenfubeta G, Lam CSP, Borlaug BA, Komtebedde J, Feldman T, Shah SJ, Burkhoff D, REDUCE-LAP-HF Trial Investigators and Advisors. Impact of Baseline Hemodynamics on the Effects of a Transcatheter Interatrial Shunt Device in Heart Failure With Preserved Ejection Fraction. Circ Heart Fail. 2018 Aug; 11 (8):e004540
    View PubMed
  306. Parikh KS, Sharma K, Fiuzat M, Surks HK, George JT, Honarpour N, Depre C, Desvigne-Nickens P, Nkulikiyinka R, Lewis GD, Gomberg-Maitland M, O'Connor CM, Stockbridge N, Califf RM, Konstam MA, Januzzi JL Jr, Solomon SD, Borlaug BA, Shah SJ, Redfield MM, Felker GM. Heart Failure With Preserved Ejection Fraction Expert Panel Report: Current Controversies and Implications for Clinical Trials. JACC Heart Fail. 2018 Aug; 6 (8):619-632
    View PubMed
  307. Fernandes-Silva MM, Shah AM, Claggett B, Cheng S, Tanaka H, Silvestre OM, Nadruz W, Borlaug BA, Solomon SD. Adiposity, body composition and ventricular-arterial stiffness in the elderly: the Atherosclerosis Risk in Communities Study. Eur J Heart Fail. 2018 Aug; 20 (8):1191-1201 Epub 2018 Apr 16
    View PubMed
  308. Reddy YNV, Olson TP, Obokata M, Melenovsky V, Borlaug BA. Hemodynamic Correlates and Diagnostic Role of Cardiopulmonary Exercise Testing in Heart Failure With Preserved Ejection Fraction. JACC Heart Fail. 2018 Aug; 6 (8):665-675 Epub 2018 May 23
    View PubMed
  309. Obokata M, Reddy YNV, Melenovsky V, Kane GC, Olson TP, Jarolim P, Borlaug BA. Myocardial Injury and Cardiac Reserve in Patients With Heart Failure and Preserved Ejection Fraction. J Am Coll Cardiol. 2018 Jul 3; 72 (1):29-40
    View PubMed
  310. Asleh R, Hasin T, Briasoulis A, Schettle SD, Borlaug BA, Behfar A, Pereira NL, Edwards BS, Clavell AL, Joyce LD, Maltais S, Stulak JM, Kushwaha SS. Hemodynamic Assessment of Patients With and Without Heart Failure Symptoms Supported by a Continuous-Flow Left Ventricular Assist Device. Mayo Clin Proc. 2018 Jul; 93 (7):895-903 Epub 2018 June 19
    View PubMed
  311. Joyce DL, Redfield MM, Kushwaha SS, Behfar A, Borlaug BA, Daly RC, Sandhu GS, Joyce LD. Pulmonary Pressure Assessment with the Total Artificial Heart. ASAIO J. 2018 May/Jun; 64 (3):e34-e36
    View PubMed
  312. Fayyaz AU, Edwards WD, Maleszewski JJ, Konik EA, DuBrock HM, Borlaug BA, Frantz RP, Jenkins SM, Redfield MM. Global Pulmonary Vascular Remodeling in Pulmonary Hypertension Associated With Heart Failure and Preserved or Reduced Ejection Fraction. Circulation. 2018 Apr 24; 137 (17):1796-1810 Epub 2017 Dec 15
    View PubMed
  313. Wolsk E, Kaye D, Borlaug BA, Burkhoff D, Kitzman DW, Komtebedde J, Lam CSP, Ponikowski P, Shah SJ, Gustafsson F. Resting and exercise haemodynamics in relation to six-minute walk test in patients with heart failure and preserved ejection fraction. Eur J Heart Fail. 2018 Apr; 20 (4):715-722 Epub 2017 Sept 26
    View PubMed
  314. Tampakakis E, Shah SJ, Borlaug BA, Leary PJ, Patel HH, Miller WL, Kelemen BW, Houston BA, Kolb TM, Damico R, Mathai SC, Kasper EK, Hassoun PM, Kass DA, Tedford RJ. Pulmonary Effective Arterial Elastance as a Measure of Right Ventricular Afterload and Its Prognostic Value in Pulmonary Hypertension Due to Left Heart Disease. Circ Heart Fail. 2018 Apr; 11 (4):e004436
    View PubMed
  315. Gorter TM, van Melle JP, Rienstra M, Borlaug BA, Hummel YM, van Gelder IC, Hoendermis ES, Voors AA, van Veldhuisen DJ, Lam CSP. Right Heart Dysfunction in Heart Failure With Preserved Ejection Fraction: The Impact of Atrial Fibrillation. J Card Fail. 2018 Mar; 24 (3):177-185 Epub 2017 Nov 29
    View PubMed
  316. Egbe AC, Connolly HM, Taggart NW, Al-Otaibi M, Borlaug BA. Invasive and noninvasive hemodynamic assessment in adults with Fontan palliation. Int J Cardiol. 2018 Mar 1; 254:96-100 Epub 2017 Dec 05
    View PubMed
  317. Bakkestrom R, Banke A, Christensen NL, Pecini R, Irmukhamedov A, Andersen M, Borlaug BA, Moller JE. Hemodynamic Characteristics in Significant Symptomatic and Asymptomatic Primary Mitral Valve Regurgitation at Rest and During Exercise. Circ Cardiovasc Imaging. 2018 Feb; 11 (2):e007171
    View PubMed
  318. Pandey A, Khera R, Park B, Haykowsky M, Borlaug BA, Lewis GD, Kitzman DW, Butler J, Berry JD. Relative Impairments in Hemodynamic Exercise Reserve Parameters in Heart Failure With Preserved Ejection Fraction: A Study-Level Pooled Analysis. JACC Heart Fail. 2018 Feb; 6 (2):117-126
    View PubMed
  319. Bakkestrom R, Banke A, Pecini R, Irmukhamedov A, Nielsen SK, Andersen MJ, Borlaug BA, Moller JE. Cardiac remodelling and haemodynamic characteristics in primary mitral valve regurgitation. Open Heart. 2018; 5 (2):e000919 Epub 2018 Dec 16
    View PubMed
  320. Reddy YNV, Obokata M, Haykowsky MJ, Borlaug BA. Skeletal Muscle Compensation for Cardiac Muscle Insufficiency in Heart Failure and Reduced Ejection Fraction. Circ Heart Fail. 2018 Jan; 11 (1):e004714
    View PubMed
  321. Gorter TM, van Veldhuisen DJ, Bauersachs J, Borlaug BA, Celutkiene J, Coats AJS, Crespo-Leiro MG, Guazzi M, Harjola VP, Heymans S, Hill L, Lainscak M, Lam CSP, Lund LH, Lyon AR, Mebazaa A, Mueller C, Paulus WJ, Pieske B, Piepoli MF, Ruschitzka F, Rutten FH, Seferovic PM, Solomon SD, Shah SJ, Triposkiadis F, Wachter R, Tschope C, de Boer RA. Right heart dysfunction and failure in heart failure with preserved ejection fraction: mechanisms and management. Position statement on behalf of the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail. 2018 Jan; 20 (1):16-37 Epub 2017 Oct 16
    View PubMed
  322. Van Iterson EH, Johnson BD, Borlaug BA, Olson TP. Physiological dead space and arterial carbon dioxide contributions to exercise ventilatory inefficiency in patients with reduced or preserved ejection fraction heart failure. Eur J Heart Fail. 2017 Dec; 19 (12):1675-1685 Epub 2017 Oct 08
    View PubMed
  323. Egbe AC, Connolly HM, Miranda WR, Ammash NM, Hagler DJ, Veldtman GR, Borlaug BA. Hemodynamics of Fontan Failure: The Role of Pulmonary Vascular Disease. Circ Heart Fail. 2017 Dec; 10 (12)
    View PubMed
  324. Hemnes AR, Beck GJ, Newman JH, Abidov A, Aldred MA, Barnard J, Berman Rosenzweig E, Borlaug BA, Chung WK, Comhair SAA, Erzurum SC, Frantz RP, Gray MP, Grunig G, Hassoun PM, Hill NS, Horn EM, Hu B, Lempel JK, Maron BA, Mathai SC, Olman MA, Rischard FP, Systrom DM, Tang WHW, Waxman AB, Xiao L, Yuan JX, Leopold JA, PVDOMICS Study Group. PVDOMICS: A Multi-Center Study to Improve Understanding of Pulmonary Vascular Disease Through Phenomics. Circ Res. 2017 Oct 27; 121 (10):1136-1139
    View PubMed
  325. Borlaug BA, Obokata M. Is it time to recognize a new phenotype? Heart failure with preserved ejection fraction with pulmonary vascular disease. Eur Heart J 2017 Oct 7; 38 (38):2874-2878
    View PubMed
  326. Lloyd JW, Nishimura RA, Borlaug BA, Eleid MF. Hemodynamic Response to Nitroprusside in Patients With Low-Gradient Severe Aortic Stenosis and Preserved Ejection Fraction. J Am Coll Cardiol. 2017 Sep 12; 70 (11):1339-1348
    View PubMed
  327. Van Iterson EH, Olson TP, Borlaug BA, Johnson BD, Snyder EM. Comparisons of Noninvasive Methods Used to Assess Exercise Stroke Volume in Heart Failure with Preserved Ejection Fraction. Med Sci Sports Exerc. 2017 Sep; 49 (9):1758-1768
    View PubMed
  328. Melenovsky V, Benes J, Franekova J, Kovar J, Borlaug BA, Segetova M, Tura A, Pelikanova T. Glucose Homeostasis, Pancreatic Endocrine Function, and Outcomes in Advanced Heart Failure. J Am Heart Assoc. 2017 Aug 7; 6 (8) Epub 2017 Aug 07
    View PubMed
  329. Reddy YNV, Andersen MJ, Obokata M, Koepp KE, Kane GC, Melenovsky V, Olson TP, Borlaug BA. Arterial Stiffening With Exercise in Patients With Heart Failure and Preserved Ejection Fraction. J Am Coll Cardiol. 2017 Jul 11; 70 (2):136-148
    View PubMed
  330. Obokata M, Reddy YNV, Pislaru SV, Melenovsky V, Borlaug BA. Evidence Supporting the Existence of a Distinct Obese Phenotype of Heart Failure With Preserved Ejection Fraction. Circulation. 2017 Jul 4; 136 (1):6-19 Epub 2017 Apr 05
    View PubMed
  331. Chandrashekar P, Park JY, Al-Hijji MA, Reddy YNV, Zack CJ, Reeder GS, Rea RF, Borlaug BA. Atrial Septostomy to Treat Stiff Left Atrium Syndrome. Circ Heart Fail. 2017 Jul; 10 (7)
    View PubMed
  332. Reddy YNV, Obokata M, Dean PG, Melenovsky V, Nath KA, Borlaug BA. Long-term cardiovascular changes following creation of arteriovenous fistula in patients with end stage renal disease. Eur Heart J. 2017 Jun 21; 38 (24):1913-1923
    View PubMed
  333. Givertz MM, Fang JC, Sorajja P, Dimas V, Forfia PR, Kapur NK, Kern MJ, Naidu SS, Borlaug BA. Executive Summary of the SCAI/HFSA Clinical Expert Consensus Document on the Use of Invasive Hemodynamics for the Diagnosis and Management of Cardiovascular Disease. J Card Fail. 2017 Jun; 23 (6):487-491 Epub 2017 Apr 25
    View PubMed
  334. Sorajja P, Borlaug BA, Dimas V, Fang JC, Forfia PR, Givertz MM, Kapur NK, Kern MJ, Naidu SS. Executive summary of the SCAI/HFSA clinical expert consensus document on the use of invasive hemodynamics for the diagnosis and management of cardiovascular disease. Catheter Cardiovasc Interv. 2017 Jun 1; 89 (7):1294-1299 Epub 2017 May 10
    View PubMed
  335. Reddy YNV, Lewis GD, Shah SJ, LeWinter M, Semigran M, Davila-Roman VG, Anstrom K, Hernandez A, Braunwald E, Redfield MM, Borlaug BA. INDIE-HFpEF (Inorganic Nitrite Delivery to Improve Exercise Capacity in Heart Failure With Preserved Ejection Fraction): Rationale and Design. Circ Heart Fail. 2017 May; 10 (5)
    View PubMed
  336. Melenovsky V, Petrak J, Mracek T, Benes J, Borlaug BA, Nuskova H, Pluhacek T, Spatenka J, Kovalcikova J, Drahota Z, Kautzner J, Pirk J, Houstek J. Myocardial iron content and mitochondrial function in human heart failure: a direct tissue analysis. Eur J Heart Fail. 2017 Apr; 19 (4):522-530 Epub 2016 Sept 19
    View PubMed
  337. Wohlfahrt P, Rokosny S, Melenovsky V, Borlaug BA, Pecenkova V, Balaz P. Reply to 'Cardiac remodeling after reduction of high-flow arteriovenous fistulas in end-stage renal disease: methodological issues'. Hypertens Res 2017 Apr; 40 (4):411 Epub 2016 Dec 01
    View PubMed
  338. Borlaug BA, Carter RE, Melenovsky V, DeSimone CV, Gaba P, Killu A, Naksuk N, Lerman L, Asirvatham SJ. Percutaneous Pericardial Resection: A Novel Potential Treatment for Heart Failure With Preserved Ejection Fraction. Circ Heart Fail. 2017 Apr; 10 (4):e003612
    View PubMed
  339. Killu AM, Naksuk N, Desimone CV, Gaba P, Suddendorf S, Powers J, Ladewig DJ, Lerman LO, Borlaug BA, Asirvatham SJ. Beating Heart Validation of Safety and Efficacy of a Percutaneous Pericardiotomy Tool. J Cardiovasc Electrophysiol. 2017 Mar; 28 (3):357-361 Epub 2016 Nov 17
    View PubMed
  340. Fernandes-Silva MM, Shah AM, Hegde S, Goncalves A, Claggett B, Cheng S, Nadruz W, Kitzman DW, Konety SH, Matsushita K, Mosley T, Lam CS, Borlaug BA, Solomon SD. Race-Related Differences in Left Ventricular Structural and Functional Remodeling in Response to Increased Afterload: The ARIC Study. JACC Heart Fail. 2017 Mar; 5 (3):157-165 Epub 2016 Dec 21
    View PubMed
  341. Obokata M, Kane GC, Reddy YN, Olson TP, Melenovsky V, Borlaug BA. Role of Diastolic Stress Testing in the Evaluation for Heart Failure With Preserved Ejection Fraction: A Simultaneous Invasive-Echocardiographic Study. Circulation. 2017 Feb 28; 135 (9):825-838 Epub 2016 Dec 30
    View PubMed
  342. AbouEzzeddine OF, McKie PM, Dunlay SM, Stevens SR, Felker GM, Borlaug BA, Chen HH, Tracy RP, Braunwald E, Redfield MM. Suppression of Tumorigenicity 2 in Heart Failure With Preserved Ejection Fraction. J Am Heart Assoc. 2017 Feb 18; 6 (2)
    View PubMed
  343. Wohlfahrt P, Melenovsky V, Redfield MM, Olson TP, Lin G, Abdelmoneim SS, Hametner B, Wassertheurer S, Borlaug BA. Aortic Waveform Analysis to Individualize Treatment in Heart Failure. Circ Heart Fail. 2017 Feb; 10 (2)
    View PubMed
  344. Ghimire A, Andersen MJ, Burrowes LM, Bouwmeester JC, Grant AD, Belenkie I, Fine NM, Borlaug BA, Tyberg JV. The reservoir-wave approach to characterize pulmonary vascular-right ventricular interactions in humans. J Appl Physiol (1985). 2016 Dec 1; 121 (6):1348-1353 Epub 2016 Oct 20
    View PubMed
  345. Borlaug BA, Kane GC, Melenovsky V, Olson TP. Abnormal right ventricular-pulmonary artery coupling with exercise in heart failure with preserved ejection fraction. Eur Heart J. 2016 Nov 14; 37 (43):3293-3302 Epub 2016 June 26
    View PubMed
  346. Borlaug BA, Melenovsky V, Koepp KE. Inhaled Sodium Nitrite Improves Rest and Exercise Hemodynamics in Heart Failure With Preserved Ejection Fraction. Circ Res. 2016 Sep 16; 119 (7):880-6 Epub 2016 July 25
    View PubMed
  347. Wohlfahrt P, Rokosny S, Melenovsky V, Borlaug BA, Pecenkova V, Balaz P. Cardiac remodeling after reduction of high-flow arteriovenous fistulas in end-stage renal disease. Hypertens Res. 2016 Sep; 39 (9):654-9 Epub 2016 May 26
    View PubMed
  348. Reddy YNV, Melenovsky V, Redfield MM, Nishimura RA, Borlaug BA. High-Output Heart Failure: A 15-Year Experience. J Am Coll Cardiol. 2016 Aug 2; 68 (5):473-482
    View PubMed
  349. Wan SH, Stevens SR, Borlaug BA, Anstrom KJ, Deswal A, Felker GM, Givertz MM, Bart BA, Tang WH, Redfield MM, Chen HH. Differential Response to Low-Dose Dopamine or Low-Dose Nesiritide in Acute Heart Failure With Reduced or Preserved Ejection Fraction: Results From the ROSE AHF Trial (Renal Optimization Strategies Evaluation in Acute Heart Failure). Circ Heart Fail. 2016 Aug; 9 (8)
    View PubMed
  350. Shah SJ, Kitzman DW, Borlaug BA, van Heerebeek L, Zile MR, Kass DA, Paulus WJ. Phenotype-Specific Treatment of Heart Failure With Preserved Ejection Fraction: A Multiorgan Roadmap. Circulation. 2016 Jul 5; 134 (1):73-90
    View PubMed
  351. Olson TP, Johnson BD, Borlaug BA. Impaired Pulmonary Diffusion in Heart Failure With Preserved Ejection Fraction. JACC Heart Fail. 2016 Jun; 4 (6):490-8
    View PubMed
  352. Hussain I, Mohammed SF, Forfia PR, Lewis GD, Borlaug BA, Gallup DS, Redfield MM. Impaired Right Ventricular-Pulmonary Arterial Coupling and Effect of Sildenafil in Heart Failure With Preserved Ejection Fraction: An Ancillary Analysis From the Phosphodiesterase-5 Inhibition to Improve Clinical Status And Exercise Capacity in Diastolic Heart Failure (RELAX) Trial. Circ Heart Fail. 2016 Apr; 9 (4):e002729
    View PubMed
  353. Reddy YN, Borlaug BA. Heart Failure With Preserved Ejection Fraction. Curr Probl Cardiol. 2016 Apr; 41: (4)145-88.
    View PubMed
  354. Redfield MM, Anstrom KJ, Levine JA, Koepp GA, Borlaug BA, Chen HH, LeWinter MM, Joseph SM, Shah SJ, Semigran MJ, Felker GM, Cole RT, Reeves GR, Tedford RJ, Tang WH, McNulty SE, Velazquez EJ, Shah MR, Braunwald E, NHLBI Heart Failure Clinical Research Network. Isosorbide Mononitrate in Heart Failure with Preserved Ejection Fraction. N Engl J Med. 2015 Dec 10; 373 (24):2314-24 Epub 2015 Nov 08
    View PubMed
  355. Melenovsky V, Andersen MJ, Andress K, Reddy YN, Borlaug BA. Lung congestion in chronic heart failure: haemodynamic, clinical, and prognostic implications. Eur J Heart Fail. 2015 Nov; 17: (11)1161-71.
    View PubMed
  356. Ye Z, Coutinho T, Pellikka PA, Villarraga HR, Borlaug BA, Kullo IJ. Associations of Alterations in Pulsatile Arterial Load With Left Ventricular Longitudinal Strain. Am J Hypertens. 2015 Nov; 28(11):1325-31. Epub 2015 Apr 03.
    View PubMed
  357. Borlaug BA, Koepp KE, Melenovsky V. Sodium Nitrite Improves Exercise Hemodynamics and Ventricular Performance in Heart Failure With Preserved Ejection Fraction. J Am Coll Cardiol. 2015 Oct 13; 66: (15)1672-82.
    View PubMed
  358. St John Sutton M, Cerkvenik J, Borlaug BA, Daubert C, Gold MR, Ghio S, Chirinos JA, Linde C, Ky B. Effects of Cardiac Resynchronization Therapy on Cardiac Remodeling and Contractile Function: Results From Resynchronization Reverses Remodeling in Systolic Left Ventricular Dysfunction (REVERSE). J Am Heart Assoc. 2015 Sep 11; 4 (9):e002054 Epub 2015 Sept 11
    View PubMed
  359. Tsang MY, Choi JO, Borlaug BA, Greason KL, Cha SS, Nishimura RA, Oh JK. Low-Flow, Low-Gradient Severe Aortic Stenosis in the Setting of Constrictive Pericarditis: Clinical Characteristics, Echocardiographic Features, and Outcomes. Circ Cardiovasc Imaging. 2015 Jul; 8: (7)e002812.
    View PubMed
  360. Borlaug BA, Lewis GD, McNulty SE, Semigran MJ, LeWinter M, Chen H, Lin G, Deswal A, Margulies KB, Redfield MM. Effects of sildenafil on ventricular and vascular function in heart failure with preserved ejection fraction. Circ Heart Fail. 2015 May; 8 (3):533-41 Epub 2015 Mar 17
    View PubMed
  361. Andersen MJ, Hwang SJ, Kane GC, Melenovsky V, Olson TP, Fetterly K, Borlaug BA. Enhanced pulmonary vasodilator reserve and abnormal right ventricular: pulmonary artery coupling in heart failure with preserved ejection fraction. Circ Heart Fail. 2015 May; 8(3):542-50. Epub 2015 Apr 09.
    View PubMed
  362. Melenovsky V, Hwang SJ, Redfield MM, Zakeri R, Lin G, Borlaug BA. Left atrial remodeling and function in advanced heart failure with preserved or reduced ejection fraction. Circ Heart Fail. 2015 Mar; 8(2):295-303. Epub 2015 Jan 15.
    View PubMed
  363. AbouEzzeddine OF, Haines P, Stevens S, Nativi-Nicolau J, Felker GM, Borlaug BA, Chen HH, Tracy RP, Braunwald E, Redfield MM. Galectin-3 in heart failure with preserved ejection fraction. A RELAX trial substudy (Phosphodiesterase-5 Inhibition to Improve Clinical Status and Exercise Capacity in Diastolic Heart Failure). JACC Heart Fail. 2015 Mar; 3 (3):245-52
    View PubMed
  364. Fleg JL, Cooper LS, Borlaug BA, Haykowsky MJ, Kraus WE, Levine BD, Pfeffer MA, Pina IL, Poole DC, Reeves GR, Whellan DJ, Kitzman DW, National Heart, Lung, and Blood Institute Working Group. Exercise training as therapy for heart failure: current status and future directions. Circ Heart Fail. 2015 Jan; 8 (1):209-20
    View PubMed
  365. Wohlfahrt P, Redfield MM, Melenovsky V, Lopez-Jimenez F, Rodeheffer RJ, Borlaug BA. Impact of chronic changes in arterial compliance and resistance on left ventricular ageing in humans. Eur J Heart Fail. 2015 Jan; 17 (1):27-34 Epub 2014 Oct 31
    View PubMed
  366. Andersen MJ, Olson TP, Melenovsky V, Kane GC, Borlaug BA. Differential hemodynamic effects of exercise and volume expansion in people with and without heart failure. Circ Heart Fail. 2015 Jan; 8(1):41-8. Epub 2014 Oct 23.
    View PubMed
  367. Zakeri R, Levine JA, Koepp GA, Borlaug BA, Chirinos JA, LeWinter M, VanBuren P, Davila-Roman VG, de las Fuentes L, Khazanie P, Hernandez A, Anstrom K, Redfield MM. Nitrate's effect on activity tolerance in heart failure with preserved ejection fraction trial: rationale and design. Circ Heart Fail. 2015 Jan; 8 (1):221-8
    View PubMed
  368. Melenovsky V, Hwang SJ, Lin G, Redfield MM, Borlaug BA. Right heart dysfunction in heart failure with preserved ejection fraction. Eur Heart J. 2014 Dec 21; 35 (48):3452-62 Epub 2014 May 29
    View PubMed
  369. van Empel VP, Mariani J, Borlaug BA, Kaye DM. Impaired myocardial oxygen availability contributes to abnormal exercise hemodynamics in heart failure with preserved ejection fraction. J Am Heart Assoc. 2014 Dec 2; 3 (6):e001293 Epub 2014 Dec 02
    View PubMed
  370. Andersen MJ, Ersboll M, Bro-Jeppesen J, Moller JE, Hassager C, Kober L, Borlaug BA, Goetze JP, Gustafsson F. Relationships between biomarkers and left ventricular filling pressures at rest and during exercise in patients after myocardial infarction. J Card Fail. 2014 Dec; 20 (12):959-67 Epub 2014 Oct 05
    View PubMed
  371. Konecny T, Khanna AD, Novak J, Jama AA, Zawadowski GM, Orban M, Pressman G, Bukartyk J, Kara T, Cetta F Jr, Borlaug BA, Somers VK, Reeder GS. Interatrial pressure gradients during simulated obstructive sleep apnea: a catheter-based study. Catheter Cardiovasc Interv. 2014 Dec 1; 84 (7):1138-45 Epub 2014 Mar 11
    View PubMed
  372. Borlaug BA. MY APPROACH to heart failure with preserved ejection fraction. Trends Cardiovasc Med. 2014 Nov; 24: (8)369-70.
    View PubMed
  373. Andersen MJ, Nishimura RA, Borlaug BA. The hemodynamic basis of exercise intolerance in tricuspid regurgitation. Circ Heart Fail. 2014 Nov; 7(6):911-7. Epub 2014 Sep 04.
    View PubMed
  374. Wohlfahrt P, Redfield MM, Lopez-Jimenez F, Melenovsky V, Kane GC, Rodeheffer RJ, Borlaug BA. Impact of general and central adiposity on ventricular-arterial aging in women and men. JACC Heart Fail. 2014 Oct; 2 (5):489-99 Epub 2014 Sept 03
    View PubMed
  375. Borlaug BA. The pathophysiology of heart failure with preserved ejection fraction. Nat Rev Cardiol. 2014 Sep; 11 (9):507-15 Epub 2014 June 24
    View PubMed
  376. van Empel VP, Kaye DM, Borlaug BA. Effects of healthy aging on the cardiopulmonary hemodynamic response to exercise. Am J Cardiol. 2014 Jul 1; 114 (1):131-5 Epub 2014 Apr 18
    View PubMed
  377. Andersen MJ, Borlaug BA. Heart failure with preserved ejection fraction: current understandings and challenges. Curr Cardiol Rep. 2014 Jul; 16 (7):501
    View PubMed
  378. Andersen MJ, Borlaug BA. Invasive hemodynamic characterization of heart failure with preserved ejection fraction. Heart Fail Clin. 2014 Jul; 10(3):435-44.
    View PubMed
  379. Mohammed SF, Borlaug BA, McNulty S, Lewis GD, Lin G, Zakeri R, Semigran MJ, LeWinter M, Hernandez AF, Braunwald E, Redfield MM. Resting ventricular-vascular function and exercise capacity in heart failure with preserved ejection fraction: a RELAX trial ancillary study. Circ Heart Fail. 2014 Jul; 7 (4):580-9 Epub 2014 May 15
    View PubMed
  380. Hwang SJ, Melenovsky V, Borlaug BA. Implications of coronary artery disease in heart failure with preserved ejection fraction. J Am Coll Cardiol. 2014 Jul 1; 63 (25 Pt A):2817-27 Epub 2014 Apr 23
    View PubMed
  381. Miles JM, Rule AD, Borlaug BA. Use of metformin in diseases of aging. Curr Diab Rep. 2014 Jun; 14 (6):490
    View PubMed
  382. Borlaug BA, Olson TP, Abdelmoneim SS, Melenovsky V, Sorrell VL, Noonan K, Lin G, Redfield MM. A randomized pilot study of aortic waveform guided therapy in chronic heart failure. J Am Heart Assoc. 2014 Mar 20; 3 (2):e000745
    View PubMed
  383. Kaye D, Shah SJ, Borlaug BA, Gustafsson F, Komtebedde J, Kubo S, Magnin C, Maurer MS, Feldman T, Burkhoff D. Effects of an interatrial shunt on rest and exercise hemodynamics: results of a computer simulation in heart failure. J Card Fail. 2014 Mar; 20(3):212-21. Epub 2014 Jan 30.
    View PubMed
  384. Borlaug BA. Mechanisms of exercise intolerance in heart failure with preserved ejection fraction. Circ J. 2014; 78 (1):20-32 Epub 2013 Dec 03
    View PubMed
  385. Zakeri R, Borlaug BA, McNulty SE, Mohammed SF, Lewis GD, Semigran MJ, Deswal A, LeWinter M, Hernandez AF, Braunwald E, Redfield MM. Impact of atrial fibrillation on exercise capacity in heart failure with preserved ejection fraction: a RELAX trial ancillary study. Circ Heart Fail. 2014 Jan; 7 (1):123-30 Epub 2013 Oct 25
    View PubMed
  386. Zhang KW, French B, Khan AM, Plappert T, Fang JC, Sweitzer NK, Borlaug BA, Chirinos JA, John Sutton MS, Cappola TP, Ky B. Strain improves risk prediction beyond ejection fraction in chronic systolic heart failure. Journal of the American Heart Association. 2014; 3(1):e000550.
    View PubMed
  387. Chen HH, Anstrom KJ, Givertz MM, Stevenson LW, Semigran MJ, Goldsmith SR, Bart BA, Bull DA, Stehlik J, LeWinter MM, Konstam MA, Huggins GS, Rouleau JL, O'Meara E, Tang WH, Starling RC, Butler J, Deswal A, Felker GM, O'Connor CM, Bonita RE, Margulies KB, Cappola TP, Ofili EO, Mann DL, Davila-Roman VG, McNulty SE, Borlaug BA, Velazquez EJ, Lee KL, Shah MR, Hernandez AF, Braunwald E, Redfield MM, NHLBI Heart Failure Clinical Research Network. Low-dose dopamine or low-dose nesiritide in acute heart failure with renal dysfunction: the ROSE acute heart failure randomized trial. JAMA. 2013 Dec 18; 310 (23):2533-43
    View PubMed
  388. Greene SJ, Gheorghiade M, Borlaug BA, Pieske B, Vaduganathan M, Burnett JC Jr, Roessig L, Stasch JP, Solomon SD, Paulus WJ, Butler J. The cGMP signaling pathway as a therapeutic target in heart failure with preserved ejection fraction. J Am Heart Assoc. 2013 Dec; 2(6):e000536. Epub 2013 Dec 11.
    View PubMed
  389. Dong YX, Madhavan M, Wu JH, Oh JK, Mitsuru M, Powell BD, Dong K, Yang YZ, Hodge DO, Nishimura RA, Packer DL, Borlaug BA, Cha YM. Acute effects of atrial fibrillation on atrial and ventricular function: a simultaneous invasive-echocardiographic hemodynamic study. Int J Cardiol 2013 Nov 30; 169 (6):e114-9 Epub 2013 Oct 12
    View PubMed
  390. Melenovsky V, Kotrc M, Borlaug BA, Marek T, Kovar J, Malek I, Kautzner J. Relationships between right ventricular function, body composition, and prognosis in advanced heart failure. J Am Coll Cardiol. 2013 Oct 29; 62 (18):1660-1670 Epub 2013 July 31
    View PubMed
  391. Ky B, French B, May Khan A, Plappert T, Wang A, Chirinos JA, Fang JC, Sweitzer NK, Borlaug BA, Kass DA, St John Sutton M, Cappola TP. Ventricular-arterial coupling, remodeling, and prognosis in chronic heart failure. J Am Coll Cardiol. 2013 Sep 24; 62(13):1165-72. Epub 2013 Jun 13.
    View PubMed
  392. Eleid MF, Nishimura RA, Sorajja P, Borlaug BA. Systemic hypertension in low-gradient severe aortic stenosis with preserved ejection fraction. Circulation. 2013 Sep 17; 128(12):1349-53. Epub 2013 Aug 16.
    View PubMed
  393. Borlaug BA, Redfield MM, Melenovsky V, Kane GC, Karon BL, Jacobsen SJ, Rodeheffer RJ. Longitudinal changes in left ventricular stiffness: a community-based study. Circ Heart Fail. 2013 Sep 1; 6 (5):944-52 Epub 2013 June 28
    View PubMed
  394. Miller WL, Grill DE, Borlaug BA. Clinical features, hemodynamics, and outcomes of pulmonary hypertension due to chronic heart failure with reduced ejection fraction: pulmonary hypertension and heart failure. JACC Heart Fail. 2013 Aug; 1 (4):290-299 Epub 2013 Aug 05
    View PubMed
  395. Eleid MF, Nishimura RA, Borlaug BA, Sorajja P. Invasive measures of afterload in low gradient severe aortic stenosis with preserved ejection fraction. Circ Heart Fail. 2013 Jul; 6(4):703-10. Epub 2013 May 24.
    View PubMed
  396. Abudiab MM, Redfield MM, Melenovsky V, Olson TP, Kass DA, Johnson BD, Borlaug BA. Cardiac output response to exercise in relation to metabolic demand in heart failure with preserved ejection fraction. Eur J Heart Fail. 2013 Jul; 15 (7):776-85 Epub 2013 Feb 20
    View PubMed
  397. Benes J, Kotrc M, Borlaug BA, Lefflerova K, Jarolim P, Bendlova B, Jabor A, Kautzner J, Melenovsky V. Resting heart rate and heart rate reserve in advanced heart failure have distinct pathophysiologic correlates and prognostic impact: a prospective pilot study. JACC Heart Fail. 2013 Jun; 1(3):259-66. Epub 2013 Jun 03.
    View PubMed
  398. Kalogeropoulos AP, Georgiopoulou VV, Borlaug BA, Gheorghiade M, Butler J. Left ventricular dysfunction with pulmonary hypertension: part 2: prognosis, noninvasive evaluation, treatment, and future research. Circ Heart Fail. 2013 May; 6(3):584-93.
    View PubMed
  399. Redfield MM, Chen HH, Borlaug BA, Semigran MJ, Lee KL, Lewis G, LeWinter MM, Rouleau JL, Bull DA, Mann DL, Deswal A, Stevenson LW, Givertz MM, Ofili EO, O'Connor CM, Felker GM, Goldsmith SR, Bart BA, McNulty SE, Ibarra JC, Lin G, Oh JK, Patel MR, Kim RJ, Tracy RP, Velazquez EJ, Anstrom KJ, Hernandez AF, Mascette AM, Braunwald E, RELAX Trial. Effect of phosphodiesterase-5 inhibition on exercise capacity and clinical status in heart failure with preserved ejection fraction: a randomized clinical trial. JAMA. 2013 Mar 27; 309 (12):1268-77
    View PubMed
  400. Andersen MJ, Ersboll M, Axelsson A, Gustafsson F, Hassager C, Kober L, Borlaug BA, Boesgaard S, Skovgaard LT, Moller JE. Sildenafil and diastolic dysfunction after acute myocardial infarction in patients with preserved ejection fraction: the Sildenafil and Diastolic Dysfunction After Acute Myocardial Infarction (SIDAMI) trial. Circulation. 2013 Mar 19; 127(11):1200-8. Epub 2013 Feb 13.
    View PubMed
  401. Georgiopoulou VV, Kalogeropoulos AP, Borlaug BA, Gheorghiade M, Butler J. Left ventricular dysfunction with pulmonary hypertension: Part 1: epidemiology, pathophysiology, and definitions. Circ Heart Fail. 2013 Mar; 6(2):344-54.
    View PubMed
  402. Lam CS, Shah AM, Borlaug BA, Cheng S, Verma A, Izzo J, Oparil S, Aurigemma GP, Thomas JD, Pitt B, Zile MR, Solomon SD. Effect of antihypertensive therapy on ventricular-arterial mechanics, coupling, and efficiency. Eur Heart J. 2013 Mar; 34(9):676-83. Epub 2012 Sep 10.
    View PubMed
  403. Coutinho T, Borlaug BA, Pellikka PA, Turner ST, Kullo IJ. Sex differences in arterial stiffness and ventricular-arterial interactions. J Am Coll Cardiol. 2013 Jan 08; 61(1):96-103. Epub 2012 Nov 01.
    View PubMed
  404. Miller WL, Grill DE, Borlaug BA. Clinical Features, Hemodynamics and Natural History of Pulmonary Hypertension due to Heart Failure with reduced Ejection Fraction. JACC: Heart Failure. 2013 (in press).
  405. Fujimoto N, Borlaug BA, Lewis GD, Hastings JL, Shafer KM, Bhella PS, Carrick-Ranson G, Levine BD. Hemodynamic responses to rapid saline loading: the impact of age, sex, and heart failure. Circulation. 2013 Jan 1; 127(1):55-62. Epub 2012 Nov 21.
    View PubMed
  406. Borlaug BA. Invasive hemodynamic characterization of Heart Failure with preserved Ejection Fraction. Heart Failure Clinics. 2013 in press.
  407. Borlaug BA. Heart Failure with preserved EF: curret understandings and challenges. Curr Cardiol Rep. 2013 in press.
  408. Mohammed SF, Borlaug BA, Roger VL, Mirzoyev SA, Rodeheffer RJ, Chirinos JA, Redfield MM. Comorbidity and ventricular and vascular structure and function in heart failure with preserved ejection fraction: a community-based study. Circ Heart Fail. 2012 Nov; 5 (6):710-9 Epub 2012 Oct 17
    View PubMed
  409. Bishu K, Deswal A, Chen HH, LeWinter MM, Lewis GD, Semigran MJ, Borlaug BA, McNulty S, Hernandez AF, Braunwald E, Redfield MM. Biomarkers in acutely decompensated heart failure with preserved or reduced ejection fraction. Am Heart J. 2012 Nov; 164 (5):763-770.e3 Epub 2012 Oct 16
    View PubMed
  410. Redfield MM, Borlaug BA, Lewis GD, Mohammed SF, Semigran MJ, Lewinter MM, Deswal A, Hernandez AF, Lee KL, Braunwald E, Heart Failure Clinical Research Network. PhosphdiesteRasE-5 Inhibition to Improve CLinical Status and EXercise Capacity in Diastolic Heart Failure (RELAX) trial: rationale and design. Circ Heart Fail. 2012 Sep 1; 5(5):653-9.
    View PubMed
  411. Fang JC, DeMarco T, Givertz MM, Borlaug BA, Lewis GD, Rame JE, Gomberg-Maitland M, Murali S, Frantz RP, McGlothlin D, Horn EM, Benza RL. World Health Organization Pulmonary Hypertension group 2: pulmonary hypertension due to left heart disease in the adult--a summary statement from the Pulmonary Hypertension Council of the International Society for Heart and Lung Transplantation. J Heart Lung Transplant. 2012 Sep; 31(9):913-33.
    View PubMed
  412. Munger TM, Dong YX, Masaki M, Oh JK, Mankad SV, Borlaug BA, Asirvatham SJ, Shen WK, Lee HC, Bielinski SJ, Hodge DO, Herges RM, Buescher TL, Wu JH, Ma C, Zhang Y, Chen PS, Packer DL, Cha YM. Electrophysiological and hemodynamic characteristics associated with obesity in patients with atrial fibrillation. J Am Coll Cardiol. 2012 Aug 28; 60(9):851-60. Epub 2012 Jun 20.
    View PubMed
  413. Guazzi M, Borlaug BA. Pulmonary hypertension due to left heart disease. Circulation. 2012 Aug 21; 126(8):975-90.
    View PubMed
  414. Andersen MJ, Ersboll M, Bro-Jeppesen J, Gustafsson F, Hassager C, Kober L, Borlaug BA, Boesgaard S, Kjaergaard J, Moller JE. Exercise hemodynamics in patients with and without diastolic dysfunction and preserved ejection fraction after myocardial infarction. Circ Heart Fail. 2012 Jul 1; 5(4):444-51. Epub 2012 Jun 15.
    View PubMed
  415. Schwartzenberg S, Redfield MM, From AM, Sorajja P, Nishimura RA, Borlaug BA. Effects of vasodilation in heart failure with preserved or reduced ejection fraction implications of distinct pathophysiologies on response to therapy. J Am Coll Cardiol. 2012 Jan 31; 59 (5):442-51
    View PubMed
  416. Tedford RJ, Hassoun PM, Mathai SC, Girgis RE, Russell SD, Thiemann DR, Cingolani OH, Mudd JO, Borlaug BA, Redfield MM, Lederer DJ, Kass DA. Pulmonary capillary wedge pressure augments right ventricular pulsatile loading. Circulation. 2012 Jan 17; 125(2):289-97. Epub 2011 Nov 30.
    View PubMed
  417. Gharacholou SM, Scott CG, Borlaug BA, Kane GC, McCully RB, Oh JK, Pellikka PA. Relationship between diastolic function and heart rate recovery after symptom-limited exercise. J Card Fail. 2012 Jan; 18 (1):34-40 Epub 2011 Nov 09
    View PubMed
  418. From AM, Lam CS, Pitta SR, Kumar PV, Balbissi KA, Booker JD, Singh IM, Sorajja P, Reeder GS, Borlaug BA. Bedside assessment of cardiac hemodynamics: the impact of noninvasive testing and examiner experience. Am J Med. 2011 Nov; 124(11):1051-7. Epub 2011 Sep 22.
    View PubMed
  419. Scantlebury DC, Borlaug BA. Why are women more likely than men to develop heart failure with preserved ejection fraction? Curr Opin Cardiol. 2011 Nov; 26 (6):562-8
    View PubMed
  420. From AM, Borlaug BA. Heart failure with preserved ejection fraction: pathophysiology and emerging therapies. Cardiovasc Ther. 2011 Aug; 29(4):e6-21. Epub 2010 Mar 29.
    View PubMed
  421. Borlaug BA, Kass DA. Ventricular-vascular interaction in heart failure. Cardiol Clin. 2011 Aug; 29(3):447-59.
    View PubMed
  422. Borlaug BA, Jaber WA, Ommen SR, Lam CS, Redfield MM, Nishimura RA. Diastolic relaxation and compliance reserve during dynamic exercise in heart failure with preserved ejection fraction. Heart. 2011 Jun; 97 (12):964-9 Epub 2011 Apr 08
    View PubMed
  423. Borlaug BA, Redfield MM. Diastolic and systolic heart failure are distinct phenotypes within the heart failure spectrum. Circulation. 2011 May 10; 123 (18):2006-13; discussion 2014
    View PubMed
  424. Borlaug BA, Kass DA. Invasive hemodynamic assessment in heart failure. Cardiol Clin. 2011 May; 29 (2):269-80
    View PubMed
  425. Borlaug BA, Paulus WJ. Heart failure with preserved ejection fraction: pathophysiology, diagnosis, and treatment. Eur Heart J. 2011 Mar; 32 (6):670-9 Epub 2010 Dec 07
    View PubMed
  426. Gharacholou SM, Maleszewski JJ, Borlaug BA, Cosio FG, Dearani JA, Kushwaha SS, Ammash NM. "Carcinoid-like" tricuspid valvulopathy associated with nephrogenic systemic fibrosis. Echocardiography. 2011 Mar; 28: (3)E46-9.
    View PubMed
  427. Sobieszczyk P, Borlaug BA, Gornik HL, Knauft WD, Beckman JA. Glycyrrhetinic acid attenuates vascular smooth muscle vasodilatory function in healthy humans. Clin Sci (Lond). 2010 Nov; 119(10):437-42. Epub 2010 Aug 05.
    View PubMed
  428. Park SJ, Nishimura RA, Borlaug BA, Sorajja P, Oh JK. The effect of loading alterations on left ventricular torsion: a simultaneous catheterization and two-dimensional speckle tracking echocardiographic study. Eur J Echocardiogr. 2010 Oct; 11(9):770-7. Epub 2010 May 18.
    View PubMed
  429. Borlaug BA, Olson TP, Lam CS, Flood KS, Lerman A, Johnson BD, Redfield MM. Global cardiovascular reserve dysfunction in heart failure with preserved ejection fraction. J Am Coll Cardiol. 2010 Sep 7; 56 (11):845-54
    View PubMed
  430. Borlaug BA, Nishimura RA, Sorajja P, Lam CS, Redfield MM. Exercise hemodynamics enhance diagnosis of early heart failure with preserved ejection fraction. Circ Heart Fail. 2010 Sep; 3 (5):588-95 Epub 2010 June 11
    View PubMed
  431. Borlaug BA, Redfield MM. Heart Failure with Reduced the Preserved Ejection Fraction Represent Distinct Phenotypes in the Heart Failure Syndrome. Circulation. 2010 Jun 14 (in press).
  432. Lam CS, Grewal J, Borlaug BA, Ommen SR, Kane GC, McCully RB, Pellikka PA. Size, shape, and stamina: the impact of left ventricular geometry on exercise capacity. Hypertension. 2010 May; 55 (5):1143-9 Epub 2010 Mar 09
    View PubMed
  433. Boilson BA, Schirger JA, Borlaug BA. Caveat medicus! Pulmonary hypertension in the elderly: a word of caution. Eur J Heart Fail. 2010 Jan; 12(1):89-93.
    View PubMed
  434. Borlaug BA. Sex, load and relaxation: Are women more susceptible to afterload-dependent diastolic dysfunciton? J Am Coll Cardiol. 2010 (n press).
  435. Madhavan M, Borlaug BA, Lerman A, Rihal CS, Prasad A. Stress hormone and circulating biomarker profile of apical ballooning syndrome (Takotsubo cardiomyopathy): insights into the clinical significance of B-type natriuretic peptide and troponin levels. Heart. 2009 Sep; 95: (17)1436-41.
    View PubMed
  436. Jaber WA, Sorajja P, Borlaug BA, Nishimura RA. Differentiation of tricuspid regurgitation from constrictive pericarditis: novel criteria for diagnosis in the cardiac catheterisation laboratory. Heart. 2009 Sep; 95(17):1449-54. Epub 2009 May 17.
    View PubMed
  437. Borlaug BA, Lam CS, Roger VL, Rodeheffer RJ, Redfield MM. Contractility and ventricular systolic stiffening in hypertensive heart disease insights into the pathogenesis of heart failure with preserved ejection fraction. J Am Coll Cardiol. 2009 Jul 28; 54 (5):410-8
    View PubMed
  438. Lam CS, Borlaug BA, Kane GC, Enders FT, Rodeheffer RJ, Redfield MM. Age-associated increases in pulmonary artery systolic pressure in the general population. Circulation. 2009 May 26; 119 (20):2663-70 Epub 2009 May 11
    View PubMed
  439. Borlaug BA, Kass DA. Invasive hemodynamic assessment in heart failure. Heart Fail Clin. 2009 Apr; 5 (2):217-28
    View PubMed
  440. Lam CS, Roger VL, Rodeheffer RJ, Borlaug BA, Enders FT, Redfield MM. Pulmonary hypertension in heart failure with preserved ejection fraction: a community-based study. J Am Coll Cardiol. 2009 Mar 31; 53 (13):1119-26
    View PubMed
  441. Borlaug BA. Treatment of heart failure with preserved ejection fraction. Curr Treat Options Cardiovasc Med. 2009 Feb; 11 (1):79-87
    View PubMed
  442. Sorajja P, Borlaug BA. Severe heart failure in the setting of relatively mild mitral stenosis: the role of invasive hemodynamic assessment. Catheter Cardiovasc Interv. 2008 Nov 1; 72(5):739-48.
    View PubMed
  443. Borlaug BA, Kass DA. Ventricular-vascular interaction in heart failure. Heart Fail Clin. 2008 Jan; 4 (1):23-36
    View PubMed
  444. Mudd JO, Borlaug BA, Johnston PV, Kral BG, Rouf R, Blumenthal RS, Kwiterovich PO Jr. Beyond low-density lipoprotein cholesterol: defining the role of low-density lipoprotein heterogeneity in coronary artery disease. J Am Coll Cardiol. 2007 Oct 30; 50(18):1735-41 Epub 2007 Oct 15.
    View PubMed
  445. Borlaug BA, Melenovsky V, Redfield MM, Kessler K, Chang HJ, Abraham TP, Kass DA. Impact of arterial load and loading sequence on left ventricular tissue velocities in humans. J Am Coll Cardiol. 2007 Oct 16; 50: (16)1570-7.
    View PubMed
  446. Melenovsky V, Borlaug BA, Fetics B, Kessler K, Shively L, Kass DA. Estimation of central pressure augmentation using automated radial artery tonometry.[see comment]. J Hypertens. 2007 Jul; 25(7):1403-9.
    View PubMed
  447. Lam CS, Roger VL, Rodeheffer RJ, Bursi F, Borlaug BA, Ommen SR, Kass DA, Redfield MM. Cardiac structure and ventricular-vascular function in persons with heart failure and preserved ejection fraction from Olmsted County, Minnesota. Circulation. 2007 Apr 17; 115 (15):1982-90 Epub 2007 Apr 02
    View PubMed
  448. Melenovsky V, Borlaug BA, Rosen B, Hay I, Ferruci L, Morell CH, Lakatta EG, Najjar SS, Kass DA. Cardiovascular features of heart failure with preserved ejection fraction versus nonfailing hypertensive left ventricular hypertrophy in the urban Baltimore community: the role of atrial remodeling/dysfunction. J Am Coll Cardiol. 2007 Jan 16; 49(2):198-207.
    View PubMed
  449. Borlaug BA, Melenovsky V, Russell SD, Kessler K, Pacak K, Becker LC, Kass DA. Impaired chronotropic and vasodilator reserves limit exercise capacity in patients with heart failure and a preserved ejection fraction. Circulation. 2006 Nov 14; 114(20):2138-47. Epub 2006 Nov 06.
    View PubMed
  450. Borlaug BA, Kass DA. Mechanisms of diastolic dysfunction in heart failure. Trends Cardiovasc Med. 2006 Nov; 16(8):273-9.
    View PubMed
  451. Forfia PR, Fisher MR, Mathai SC, Housten-Harris T, Hemnes AR, Borlaug BA, Chamera E, Corretti MC, Champion HC, Abraham TP, Girgis RE, Hassoun PM. Tricuspid annular displacement predicts survival in pulmonary hypertension. Am J Respir Crit Care Med. 2006 Nov 1; 174(9):1034-41. Epub 2006 Aug 03.
    View PubMed
  452. Borlaug BA, Melenovsky V, Marhin T, Fitzgerald P, Kass DA. Sildenafil inhibits beta-adrenergic-stimulated cardiac contractility in humans. Circulation. 2005 Oct 25; 112(17):2642-9.
    View PubMed
  453. Redfield MM, Jacobsen SJ, Borlaug BA, Rodeheffer RJ, Kass DA. Age- and gender-related ventricular-vascular stiffening: a community-based study. Circulation. 2005 Oct 11; 112 (15):2254-62 Epub 2005 Oct 03
    View PubMed
  454. Melenovsky V, Hay I, Fetics BJ, Borlaug BA, Kramer A, Pastore JM, Berger R, Kass DA. Functional impact of rate irregularity in patients with heart failure and atrial fibrillation receiving cardiac resynchronization therapy. Eur Heart J. 2005 Apr; 26(7):705-11.
    View PubMed
PST-20224197