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Parkinsonism Relat Disord. 2020 Feb; 71:36-39 Epub 2020 Jan 11 View PubMed Beach TG, Adler CH, Zhang N, Serrano GE, Sue LI, Driver-Dunckley E, Mehta SH, Zamrini EE, Sabbagh MN, Shill HA, Belden CM, Shprecher DR, Caselli RJ, Reiman EM, Davis KJ, Long KE, Nicholson LR, Intorcia AJ, Glass MJ, Walker JE, Callan MM, Oliver JC, Arce R, Gerkin RC. Severe hyposmia distinguishes neuropathologically confirmed dementia with Lewy bodies from Alzheimer's disease dementia. PLoS One. 2020; 15 (4):e0231720 Epub 2020 Apr 22 View PubMed Serrano GE, Shprecher D, Callan M, Cutler B, Glass M, Zhang N, Walker J, Intorcia A, Adler CH, Shill HA, Driver-Dunckley E, Mehta SH, Belden CM, Zamrini E, Sue LI, Vargas D, Beach TG. Cardiac sympathetic denervation and synucleinopathy in Alzheimer's disease with brain Lewy body disease. Brain Commun. 2020; 2 (1):fcaa004 Epub 2020 Jan 28 View PubMed Gupta HV, Zhang N, Driver-Dunckley E, Mehta SH, Beach TG, Adler CH. Contrast Acuity With Different Colors in Parkinson's Disease. Mov Disord Clin Pract. 2019 Nov; 6 (8):672-677 Epub 2019 Sept 06 View PubMed Adler CH, Serrano GE, Zhang N, Hinni ML, Lott DG, Mehta SH, Sue LI, Intorcia A, Beach TG. Feasibility of repeat and bilateral submandibular gland needle biopsies in Parkinson's disease. Parkinsonism Relat Disord. 2019 Nov; 68:69-72 Epub 2019 Oct 07 View PubMed Dashtipour K, Mari Z, Jankovic J, Adler CH, Schwartz M, Brin MF. Minimal clinically important change in patients with cervical dystonia: Results from the CD PROBE study. J Neurol Sci. 2019 Oct 15; 405:116413 Epub 2019 July 27 View PubMed Adler CH, Beach TG, Zhang N, Shill HA, Driver-Dunckley E, Caviness JN, Mehta SH, Sabbagh MN, Serrano GE, Sue LI, Belden CM, Powell J, Jacobson SA, Zamrini E, Shprecher D, Davis KJ, Dugger BN, Hentz JG. Unified Staging System for Lewy Body Disorders: Clinicopathologic Correlations and Comparison to Braak Staging. J Neuropathol Exp Neurol. 2019 Oct 1; 78 (10):891-899 View PubMed Driver-Dunckley ED, Zhang N, Shill HA, Mehta SH, Belden CM, Zamrini EY, Davis K, Beach TG, Adler CH. Correlation Between the Movement Disorder Society's Unified Parkinson's Disease Rating Scale and Nonmotor Scales in Patients with Parkinson's Disease. Innov Clin Neurosci. 2019 Sep 1; 16 (9-10):27-29 View PubMed El-Nazer R, Adler CH, Beach TG, Belden CM, Artz J, Shill HA, Driver-Dunckley E, Mehta SH, Sabbagh MN, Serrano GE, Sue LI, Zamrini E, Benge JF. Regional neuropathology distribution and verbal fluency impairments in Parkinson's disease. Parkinsonism Relat Disord. 2019 Aug; 65:73-78 Epub 2019 May 10 View PubMed Stern RA, Adler CH, Chen K, Navitsky M, Luo J, Dodick DW, Alosco ML, Tripodis Y, Goradia DD, Martin B, Mastroeni D, Fritts NG, Jarnagin J, Devous MD Sr, Mintun MA, Pontecorvo MJ, Shenton ME, Reiman EM. Tau Positron-Emission Tomography in Former National Football League Players. N Engl J Med. 2019 May 2; 380 (18):1716-1725 Epub 2019 Apr 10 View PubMed Dugger BN, Hoffman BR, Scroggins A, Serrano GE, Adler CH, Shill HA, Belden CM, Sabbagh MN, Caviness JN, Driver Dunckley E, Beach TG. Tau immunoreactivity in peripheral tissues of human aging and select tauopathies. Neurosci Lett. 2019 Mar 23; 696:132-139 Epub 2018 Dec 21 View PubMed Hoogland J, Boel JA, de Bie RMA, Schmand BA, Geskus RB, Dalrymple-Alford JC, Marras C, Adler CH, Weintraub D, Junque C, Pedersen KF, Mollenhauer B, Goldman JG, Troster AI, Burn DJ, Litvan I, Geurtsen GJ, MDS Study Group "Validation of Mild Cognitive Impairment in Parkinson Disease". Risk of Parkinson's disease dementia related to level I MDS PD-MCI. Mov Disord. 2019 Mar; 34 (3):430-435 Epub 2019 Jan 17 View PubMed Dong X, Liao Z, Gritsch D, Hadzhiev Y, Bai Y, Locascio JJ, Guennewig B, Liu G, Blauwendraat C, Wang T, Adler CH, Hedreen JC, Faull RLM, Frosch MP, Nelson PT, Rizzu P, Cooper AA, Heutink P, Beach TG, Mattick JS, Muller F, Scherzer CR. Publisher Correction: Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease. Nat Neurosci. 2019 Jan; 22 (1):144-147 View PubMed Malek-Ahmadi M, Beach TG, Zamrini E, Adler CH, Sabbagh MN, Shill HA, Jacobson SA, Belden CM, Caselli RJ, Woodruff BK, Rapscak SZ, Ahern GL, Shi J, Caviness JN, Driver-Dunckley E, Mehta SH, Shprecher DR, Spann BM, Tariot P, Davis KJ, Long KE, Nicholson LR, Intorcia A, Glass MJ, Walker JE, Callan M, Curry J, Cutler B, Oliver J, Arce R, Walker DG, Lue LF, Serrano GE, Sue LI, Chen K, Reiman EM. Faster cognitive decline in dementia due to Alzheimer disease with clinically undiagnosed Lewy body disease. PLoS One. 2019; 14 (6):e0217566 Epub 2019 June 25 View PubMed Savica R, Beach TG, Hentz JG, Sabbagh MN, Serrano GE, Sue LI, Dugger BN, Shill HA, Driver-Dunckley E, Caviness JN, Mehta SH, Jacobson SA, Belden CM, Davis KJ, Zamrini E, Shprecher DR, Adler CH. Lewy body pathology in Alzheimer's disease: A clinicopathological prospective study. Acta Neurol Scand. 2019 Jan; 139 (1):76-81 Epub 2018 Oct 07 View PubMed Driver-Dunckley ED, Zhang N, Adler CH, Serrano GE, Sue LI, Shill HA, Mehta SH, Belden CM, Zamrini EY, Davis K, Beach TG. Brain Lewy-Type Synucleinopathy Density Is Associated with a Lower Prevalence of Atherosclerotic Cardiovascular Disease Risk Factors in Patients with Parkinson's Disease1. J Parkinsons Dis. 2019; 9 (3):543-552 View PubMed Black KJ, Nasrallah H, Isaacson S, Stacy M, Pahwa R, Adler CH, Alva G, Cooney JW, Kremens D, Menza MA, Meyer JM, Patkar AA, Simuni T, Morrissette DA, Stahl SM. Guidance for switching from off-label antipsychotics to pimavanserin for Parkinson's disease psychosis: an expert consensus. CNS Spectr. 2018 Dec; 23 (6):402-413 View PubMed Hoogland J, van Wanrooij LL, Boel JA, Goldman JG, Stebbins GT, Dalrymple-Alford JC, Marras C, Adler CH, Junque C, Pedersen KF, Mollenhauer B, Zabetian CP, Eslinger PJ, Lewis SJG, Wu RM, Klein M, Rodriguez-Oroz MC, Cammisuli DM, Barone P, Biundo R, de Bie RMA, Schmand BA, Troster AI, Burn DJ, Litvan I, Filoteo JV, Geurtsen GJ, Weintraub D, IPMDS Study Group "Validation of Mild Cognitive Impairment in Parkinson Disease". Detecting Mild Cognitive Deficits in Parkinson's Disease: Comparison of Neuropsychological Tests. Mov Disord. 2018 Nov; 33 (11):1750-1759 Epub 2018 Sept 14 View PubMed Adler CH, Temkit M, Crews D, McDaniel T, Tucker J, Hentz JG, Marquardt C, Abraham D, Caviness JN. The Yips: Methods to Identify Golfers with a Dystonic Etiology/Golfer's Cramp. Med Sci Sports Exerc. 2018 Nov; 50 (11):2226-2230 View PubMed Berg D, Adler CH, Bloem BR, Chan P, Gasser T, Goetz CG, Halliday G, Lang AE, Lewis S, Li Y, Liepelt-Scarfone I, Litvan I, Marek K, Maetzler C, Mi T, Obeso J, Oertel W, Olanow CW, Poewe W, Rios-Romenets S, Schaffer E, Seppi K, Heim B, Slow E, Stern M, Bledsoe IO, Deuschl G, Postuma RB. Movement disorder society criteria for clinically established early Parkinson's disease. Mov Disord. 2018 Oct; 33 (10):1643-1646 Epub 2018 Aug 25 View PubMed Dong X, Liao Z, Gritsch D, Hadzhiev Y, Bai Y, Locascio JJ, Guennewig B, Liu G, Blauwendraat C, Wang T, Adler CH, Hedreen JC, Faull RLM, Frosch MP, Nelson PT, Rizzu P, Cooper AA, Heutink P, Beach TG, Mattick JS, Muller F, Scherzer CR. Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease. Nat Neurosci. 2018 Oct; 21 (10):1482-1492 Epub 2018 Sept 17 View PubMed Beach TG, Adler CH. Importance of low diagnostic Accuracy for early Parkinson's disease. Mov Disord. 2018 Oct; 33 (10):1551-1554 Epub 2018 Oct 04 View PubMed Shprecher DR, Adler CH, Zhang N, Hentz JG, Serrano GE, Dugger BN, Shill HA, Savica R, Caviness JN, Sabbagh MN, Belden CM, Driver-Dunckley E, Mehta SH, Sue LI, Davis KJ, Zamrini E, Beach TG. Predicting alpha-synuclein pathology by REM sleep behavior disorder diagnosis. Parkinsonism Relat Disord. 2018 Oct; 55:92-96 Epub 2018 May 17 View PubMed Ortuno-Lizaran I, Esquiva G, Beach TG, Serrano GE, Adler CH, Lax P, Cuenca N. Degeneration of human photosensitive retinal ganglion cells may explain sleep and circadian rhythms disorders in Parkinson's disease. Acta Neuropathol Commun. 2018 Sep 10; 6 (1):90 Epub 2018 Sept 10 View PubMed Beach TG, Serrano GE, Kremer T, Canamero M, Dziadek S, Sade H, Derkinderen P, Corbille AG, Letournel F, Munoz DG, White CL 3rd, Schneider J, Crary JF, Sue LI, Adler CH, Glass MJ, Intorcia AJ, Walker JE, Foroud T, Coffey CS, Ecklund D, Riss H, Gossmann J, Konig F, Kopil CM, Arnedo V, Riley L, Linder C, Dave KD, Jennings D, Seibyl J, Mollenhauer B, Chahine L, Systemic Synuclein Sampling Study (S4). Immunohistochemical Method and Histopathology Judging for the Systemic Synuclein Sampling Study (S4). J Neuropathol Exp Neurol. 2018 Sep 1; 77 (9):793-802 View PubMed Caviness JN, Beach TG, Hentz JG, Shill HA, Driver-Dunckley ED, Adler CH. Association Between Pathology and Electroencephalographic Activity in Parkinson's Disease. Clin EEG Neurosci. 2018 Sep; 49 (5):321-327 Epub 2017 Feb 01 View PubMed Claassen DO, Adler CH, Hewitt LA, Gibbons C. Characterization of the symptoms of neurogenic orthostatic hypotension and their impact from a survey of patients and caregivers. BMC Neurol. 2018 Aug 25; 18 (1):125 View PubMed Ludlow CL, Domangue R, Sharma D, Jinnah HA, Perlmutter JS, Berke G, Sapienza C, Smith ME, Blumin JH, Kalata CE, Blindauer K, Johns M, Hapner E, Harmon A, Paniello R, Adler CH, Crujido L, Lott DG, Bansberg SF, Barone N, Drulia T, Stebbins G. Consensus-Based Attributes for Identifying Patients With Spasmodic Dysphonia and Other Voice Disorders. JAMA Otolaryngol Head Neck Surg. 2018 Aug 1; 144 (8):657-665 View PubMed Ortuno-Lizaran I, Beach TG, Serrano GE, Walker DG, Adler CH, Cuenca N. Phosphorylated alpha-synuclein in the retina is a biomarker of Parkinson's disease pathology severity. Mov Disord. 2018 Aug; 33 (8):1315-1324 Epub 2018 May 08 View PubMed Gupta HV, Mehta SH, Zhang N, Hentz JG, Shill HA, Driver-Dunckley E, Sabbagh MN, Belden CM, Dugger BN, Beach TG, Serrano GE, Sue LI, Davis K, Adler CH. Are Clinical Certainty Ratings Helpful in the Diagnosis of Parkinson's Disease? Mov Disord Clin Pract. 2018 Mar-Apr; 5 (2):165-170 Epub 2018 Feb 22 View PubMed Isaacson SH, Fahn S, Pahwa R, Tanner CM, Espay AJ, Trenkwalder C, Adler CH, Patni R, Johnson R. Parkinson's Patients with Dyskinesia Switched from Immediate Release Amantadine to Open-label ADS-5102. Mov Disord Clin Pract. 2018 Mar-Apr; 5 (2):183-190 Epub 2018 Feb 23 View PubMed Park HJ, Lee KW, Oh S, Yan R, Zhang J, Beach TG, Adler CH, Voronkov M, Braithwaite SP, Stock JB, Mouradian MM. Protein Phosphatase 2A and Its Methylation Modulating Enzymes LCMT-1 and PME-1 Are Dysregulated in Tauopathies of Progressive Supranuclear Palsy and Alzheimer Disease. J Neuropathol Exp Neurol. 2018 Feb 1; 77 (2):139-148 View PubMed Dong X, Liao Z, Gritsch D, Hadzhiev Y, Bai Y, Locascio JJ, Guennewig B, Liu G, Blauwendraat C, Wang T, Adler CH, Hedreen JC, Faull RLM, Frosch MP, Nelson PT, Rizzu P, Cooper AA, Heutink P, Beach TG, Mattick JS, Scherzer CR. Erratum to: Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease (Nature Neuroscience, (2018), 21, 10, (1482-1492), 10.1038/s41593-018-0223-0) Nature Neuroscience. 2018; 22 (1):144-7 Chahine LM, Beach TG, Seedorff N, Caspell-Garcia C, Coffey CS, Brumm M, Adler CH, Serrano GE, Linder C, Mosovsky S, Foroud T, Riss H, Ecklund D, Seibyl J, Jennings D, Arnedo V, Riley L, Dave KD, Mollenhauer B, Systemic sSynuclein Sampling study. Feasibility and Safety of Multicenter Tissue and Biofluid Sampling for alpha-Synuclein in Parkinson's Disease: The Systemic Synuclein Sampling Study (S4). J Parkinsons Dis. 2018; 8 (4):517-527 View PubMed DiBaise JK, Crowell MD, Driver-Dunckley E, Mehta SH, Hoffman-Snyder C, Lin T, Adler CH. Weight Loss in Parkinson's Disease: No Evidence for Role of Small Intestinal Bacterial Overgrowth. J Parkinsons Dis. 2018; 8 (4):571-581 View PubMed Lionnet A, Leclair-Visonneau L, Neunlist M, Murayama S, Takao M, Adler CH, Derkinderen P, Beach TG. Does Parkinson's disease start in the gut? Acta Neuropathol. 2018 Jan; 135 (1):1-12 Epub 2017 Oct 16 View PubMed Adler CH, Beach TG, Shill HA, Caviness JN, Driver-Dunckley E, Sabbagh MN, Patel A, Sue LI, Serrano G, Jacobson SA, Davis K, Belden CM, Dugger BN, Paciga SA, Winslow AR, Hirst WD, Hentz JG. GBA mutations in Parkinson disease: earlier death but similar neuropathological features. Eur J Neurol. 2017 Nov; 24 (11):1363-1368 Epub 2017 Aug 17 View PubMed Aslam S, Zhang N, Adler CH, Caviness JN, Driver-Dunckley E, Mehta SH, Sabbagh MN, Belden C, Zamrini E, Beach TG, Shill HA. Essential tremor and depression. Mov Disord Clin Pract. 2017 Nov-Dec; 4 (6):838-842 Epub 2017 July 17 View PubMed Hintze JM, Ludlow CL, Bansberg SF, Adler CH, Lott DG. Spasmodic Dysphonia: A Review. Part 2: Characterization of Pathophysiology. Otolaryngol Head Neck Surg. 2017 Oct; 157 (4):558-564 Epub 2017 Aug 29 View PubMed Hintze JM, Ludlow CL, Bansberg SF, Adler CH, Lott DG. Spasmodic Dysphonia: A Review. Part 1: Pathogenic Factors. Otolaryngol Head Neck Surg. 2017 Oct; 157 (4):551-557 Epub 2017 Aug 29 View PubMed Gerkin RC, Adler CH, Hentz JG, Shill HA, Driver-Dunckley E, Mehta SH, Sabbagh MN, Caviness JN, Dugger BN, Serrano G, Belden C, Smith BH, Sue L, Davis KJ, Zamrini E, Beach TG. Improved diagnosis of Parkinson's disease from a detailed olfactory phenotype. Ann Clin Transl Neurol. 2017 Oct; 4 (10):714-721 Epub 2017 Sept 08 View PubMed Hoogland J, Boel JA, de Bie RMA, Geskus RB, Schmand BA, Dalrymple-Alford JC, Marras C, Adler CH, Goldman JG, Troster AI, Burn DJ, Litvan I, Geurtsen GJ, MDS Study Group "Validation of Mild Cognitive Impairment in Parkinson Disease". Mild cognitive impairment as a risk factor for Parkinson's disease dementia. Mov Disord. 2017 Jul; 32 (7):1056-1065 Epub 2017 June 12 View PubMed Dashtipour K, Tafreshi A, Adler C, Beach T, Chen X, Serrano G, Tashiro S, Wang C. Hypermethylation of Synphilin-1, Alpha-Synuclein-Interacting Protein (SNCAIP) Gene in the Cerebral Cortex of Patients with Sporadic Parkinson's Disease. Brain Sci. 2017 Jun 27; 7 (7) Epub 2017 June 27 View PubMed Walker DG, Lue LF, Tang TM, Adler CH, Caviness JN, Sabbagh MN, Serrano GE, Sue LI, Beach TG. Changes in CD200 and intercellular adhesion molecule-1 (ICAM-1) levels in brains of Lewy body disorder cases are associated with amounts of Alzheimer's pathology not alpha-synuclein pathology. Neurobiol Aging. 2017 Jun; 54:175-186 Epub 2017 Mar 16 View PubMed Trosch RM, Espay AJ, Truong D, Gil R, Singer C, LeWitt PA, Lew MF, Tagliati M, Adler CH, Chen JJ, Marchese D, Comella CL. Multicenter observational study of abobotulinumtoxinA neurotoxin in cervical dystonia: The ANCHOR-CD registry. J Neurol Sci. 2017 May 15; 376:84-90 Epub 2017 Feb 21 View PubMed Adler CH, Dugger BN, Hentz JG, Hinni ML, Lott DG, Driver-Dunckley E, Mehta S, Serrano G, Sue LI, Duffy A, Intorcia A, Filon J, Pullen J, Walker DG, Beach TG. Peripheral synucleinopathy in early Parkinson's disease: Submandibular gland needle biopsy findings. Mov Disord. 2017 May; 32: (5)722-723. View PubMed Visanji NP, Mollenhauer B, Beach TG, Adler CH, Coffey CS, Kopil CM, Dave KD, Foroud T, Chahine L, Jennings D, Systemic Synuclein Sampling Study (S4). The Systemic Synuclein Sampling Study: toward a biomarker for Parkinson's disease. Biomark Med. 2017 Apr; 11 (4):359-368 Epub 2017 Mar 29 View PubMed Pal GD, Ouyang B, Serrano G, Shill HA, Goetz C, Stebbins G, Metman LV, Driver-Dunckley E, Mehta SH, Caviness JN, Sabbagh MN, Adler CH, Beach TG, Arizona Study of Aging Neurodegenerative Disorders. Comparison of neuropathology in Parkinson's disease subjects with and without deep brain stimulation. Mov Disord. 2017 Feb; 32 (2):274-277 Epub 2016 Dec 02 View PubMed Lee JM, Derkinderen P, Kordower JH, Freeman R, Munoz DG, Kremer T, Zago W, Hutten SJ, Adler CH, Serrano GE, Beach TG. The Search for a Peripheral Biopsy Indicator of alpha-Synuclein Pathology for Parkinson Disease. J Neuropathol Exp Neurol. 2017 Jan 1; 76 (1):2-15 View PubMed Hopfner F, Haubenberger D, Galpern WR, Gwinn K, Van't Veer A, White S, Bhatia K, Adler CH, Eidelberg D, Ondo W, Stebbins GT, Tanner CM, Helmich RC, Lenz FA, Sillitoe RV, Vaillancourt D, Vitek JL, Louis ED, Shill HA, Frosch MP, Foroud T, Kuhlenbaumer G, Singleton A, Testa CM, Hallett M, Elble R, Deuschl G. Knowledge gaps and research recommendations for essential tremor. Parkinsonism Relat Disord. 2016 Dec; 33:27-35 Epub 2016 Oct 04 View PubMed Postuma RB, Berg D, Stern M, Poewe W, Olanow CW, Oertel W, Marek K, Litvan I, Lang AE, Halliday G, Goetz CG, Gasser T, Dubois B, Chan P, Bloem BR, Adler CH, Deuschl G. Abolishing the 1-year rule: How much evidence will be enough? Mov Disord. 2016 Nov; 31 (11):1623-1627 Epub 2016 Sept 26 View PubMed Beach TG, Corbille AG, Letournel F, Kordower JH, Kremer T, Munoz DG, Intorcia A, Hentz J, Adler CH, Sue LI, Walker J, Serrano G, Derkinderen P. Multicenter Assessment of Immunohistochemical Methods for Pathological Alpha-Synuclein in Sigmoid Colon of Autopsied Parkinson's Disease and Control Subjects. J Parkinsons Dis. 2016 Oct 19; 6 (4):761-770 View PubMed Park HJ, Lee KW, Park ES, Oh S, Yan R, Zhang J, Beach TG, Adler CH, Voronkov M, Braithwaite SP, Stock JB, Mouradian MM. Dysregulation of protein phosphatase 2A in parkinson disease and dementia with lewy bodies. Ann Clin Transl Neurol. 2016 Oct; 3 (10):769-780 Epub 2016 Sept 07 View PubMed Filon JR, Intorcia AJ, Sue LI, Vazquez Arreola E, Wilson J, Davis KJ, Sabbagh MN, Belden CM, Caselli RJ, Adler CH, Woodruff BK, Rapscak SZ, Ahern GL, Burke AD, Jacobson S, Shill HA, Driver-Dunckley E, Chen K, Reiman EM, Beach TG, Serrano GE. Gender Differences in Alzheimer Disease: Brain Atrophy, Histopathology Burden, and Cognition. J Neuropathol Exp Neurol. 2016 Aug; 75 (8):748-754 Epub 2016 June 12 View PubMed Adler CH, Beach TG. Neuropathological basis of nonmotor manifestations of Parkinson's disease. Mov Disord. 2016 Aug; 31 (8):1114-9 Epub 2016 Mar 31 View PubMed Caviness JN, Lue LF, Hentz JG, Schmitz CT, Adler CH, Shill HA, Sabbagh MN, Beach TG, Walker DG. Cortical phosphorylated alpha-Synuclein levels correlate with brain wave spectra in Parkinson's disease. Mov Disord. 2016 Jul; 31 (7):1012-9 Epub 2016 Apr 08 View PubMed Henderson-Smith A, Corneveaux JJ, De Both M, Cuyugan L, Liang WS, Huentelman M, Adler C, Driver-Dunckley E, Beach TG, Dunckley TL. Next-generation profiling to identify the molecular etiology of Parkinson dementia. Neurol Genet. 2016 Jun; 2 (3):e75 Epub 2016 May 24 View PubMed Adler CH, Hentz JG, Beach TG. Assessing medication role on neuropathological findings in Parkinson's disease. Mov Disord 2016 May; 31 (5):613-4 Epub 2016 Feb 16 View PubMed Utianski RL, Caviness JN, van Straaten EC, Beach TG, Dugger BN, Shill HA, Driver-Dunckley ED, Sabbagh MN, Mehta S, Adler CH, Hentz JG. Graph theory network function in Parkinson's disease assessed with electroencephalography. Clin Neurophysiol. 2016 May; 127: (5)2228-36. View PubMed Comella CL, Perlmutter JS, Jinnah HA, Waliczek TA, Rosen AR, Galpern WR, Adler CA, Barbano RL, Factor SA, Goetz CG, Jankovic J, Reich SG, Rodriguez RL, Severt WL, Zurowski M, Fox SH, Stebbins GT. Clinimetric testing of the comprehensive cervical dystonia rating scale. Mov Disord. 2016 Apr; 31 (4):563-9 Epub 2016 Mar 12 View PubMed Molho ES, Stacy M, Gillard P, Charles D, Adler CH, Jankovic J, Schwartz M, Brin MF. Impact of Cervical Dystonia on Work Productivity: An Analysis From a Patient Registry. Mov Disord Clin Pract. 2016 Mar-Apr; 3 (2):130-138 Epub 2015 Dec 16 View PubMed Toledo JB, Gopal P, Raible K, Irwin DJ, Brettschneider J, Sedor S, Waits K, Boluda S, Grossman M, Van Deerlin VM, Lee EB, Arnold SE, Duda JE, Hurtig H, Lee VM, Adler CH, Beach TG, Trojanowski JQ. Pathological alpha-synuclein distribution in subjects with coincident Alzheimer's and Lewy body pathology. Acta Neuropathol. 2016 Mar; 131 (3):393-409 Epub 2015 Dec 31 View PubMed Caviness JN, Utianski RL, Hentz JG, Beach TG, Dugger BN, Shill HA, Driver-Dunckley ED, Sabbagh MN, Mehta S, Adler CH. Differential spectral quantitative electroencephalography patterns between control and Parkinson's disease cohorts. Eur J Neurol. 2016 Feb; 23 (2):387-92 Epub 2015 Oct 31 View PubMed Adler CH, Dugger BN, Hentz JG, Hinni ML, Lott DG, Driver-Dunckley E, Mehta S, Serrano G, Sue LI, Duffy A, Intorcia A, Filon J, Pullen J, Walker DG, Beach TG. Peripheral Synucleinopathy in Early Parkinson's Disease: Submandibular Gland Needle Biopsy Findings. 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Clinical-Genetic Associations in the Prospective Huntington at Risk Observational Study (PHAROS): Implications for Clinical Trials. JAMA Neurol. 2016 Jan; 73 (1):102-10 View PubMed Shill HA, Hentz JG, Caviness JN, Driver-Dunckley E, Jacobson S, Belden C, Sabbagh MN, Beach TG, Adler CH. Unawareness of Hyposmia in Elderly People With and Without Parkinson's Disease. Mov Disord Clin Pract. 2016 Jan-Feb; 3 (1):43-47 Epub 2015 July 17 View PubMed Hentz JG, Mehta SH, Shill HA, Driver-Dunckley E, Beach TG, Adler CH. Simplified conversion method for unified Parkinson's disease rating scale motor examinations. Mov Disord. 2015 Dec; 30 (14):1967-70 Epub 2015 Nov 17 View PubMed Janelidze S, Lindqvist D, Francardo V, Hall S, Zetterberg H, Blennow K, Adler CH, Beach TG, Serrano GE, van Westen D, Londos E, Cenci MA, Hansson O. Increased CSF biomarkers of angiogenesis in Parkinson disease. 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Feasibility Study: Comparison of Frontal Cortex Needle Core Versus Open Biopsy for Detection of Characteristic Proteinopathies of Neurodegenerative Diseases. J Neuropathol Exp Neurol. 2015 Sep; 74 (9):934-42 View PubMed Postuma RB, Adler CH, Dugger BN, Hentz JG, Shill HA, Driver-Dunckley E, Sabbagh MN, Jacobson SA, Belden CM, Sue LI, Serrano G, Beach TG. REM sleep behavior disorder and neuropathology in Parkinson's disease. Mov Disord. 2015 Sep; 30 (10):1413-7 Epub 2015 Aug 12 View PubMed Dugger BN, Davis K, Malek-Ahmadi M, Hentz JG, Sandhu S, Beach TG, Adler CH, Caselli RJ, Johnson TA, Serrano GE, Shill HA, Belden C, Driver-Dunckley E, Caviness JN, Sue LI, Jacobson S, Powell J, Sabbagh MN. Neuropathological comparisons of amnestic and nonamnestic mild cognitive impairment. BMC Neurol. 2015 Aug 20; 15:146 View PubMed Mu LC, Chen JM, Sobotka S, Nyirenda T, Benson B, Gupta F, Sanders I, Adler CH, Caviness JN, Shill HA, Sabbagh M, Samanta JE, Sue LI, Beach TG. Alpha-synuclein pathology in sensory nerve terminals of the upper aerodigestive tract of Parkinson's disease patients. Dysphagia. 2015 Aug; 30(4):404-17. View PubMed Beach TG, Adler CH, Sue LI, Serrano G, Shill HA, Walker DG, Lue L, Roher AE, Dugger BN, Maarouf C, Birdsill AC, Intorcia A, Saxon-Labelle M, Pullen J, Scroggins A, Filon J, Scott S, Hoffman B, Garcia A, Caviness JN, Hentz JG, Driver-Dunckley E, Jacobson SA, Davis KJ, Belden CM, Long KE, Malek-Ahmadi M, Powell JJ, Gale LD, Nicholson LR, Caselli RJ, Woodruff BK, Rapscak SZ, Ahern GL, Shi J, Burke AD, Reiman EM, Sabbagh MN. Arizona Study of Aging and Neurodegenerative Disorders and Brain and Body Donation Program. Neuropathology. 2015 Aug; 35 (4):354-89 Epub 2015 Jan 26 View PubMed Rigby HB, Dugger BN, Hentz JG, Adler CH, Beach TG, Shill HA, Driver-Dunckley E, Sabbagh MN, Sue LI, Caviness JN. Clinical Features of Patients with Concomitant Parkinson's Disease and Progressive Supranuclear Palsy Pathology. Mov Disord Clin Pract. 2015 Mar; 2 (1):33-38 Epub 2014 Oct 29 View PubMed Jankovic J, Adler CH, Charles D, Comella C, Stacy M, Schwartz M, Manack Adams A, Brin MF. Primary results from the cervical dystonia patient registry for observation of onabotulinumtoxina efficacy (CD PROBE). J Neurol Sci. 2015 Feb 15; 349 (1-2):84-93 Epub 2014 Dec 27 View PubMed Walker DG, Lue LF, Serrano G, Adler CH, Caviness JN, Sue LI, Beach TG. Altered Expression Patterns of Inflammation-Associated and Trophic Molecules in Substantia Nigra and Striatum Brain Samples from Parkinson's Disease, Incidental Lewy Body Disease and Normal Control Cases. Front Neurosci. 2015; 9:507 Epub 2016 Jan 14 View PubMed Caviness JN, Hentz JG, Belden CM, Shill HA, Driver-Dunckley ED, Sabbagh MN, Powell JJ, Adler CH. Longitudinal EEG changes correlate with cognitive measure deterioration in Parkinson's disease. J Parkinsons Dis. 2015; 5 (1):117-24 View PubMed Lin TP, Rigby H, Adler JS, Hentz JG, Balcer LJ, Galetta SL, Devick S, Cronin R, Adler CH. Abnormal visual contrast acuity in Parkinson's disease. J Parkinsons Dis. 2015; 5(1):125-30. View PubMed Driver-Dunckley E, Adler CH, Hentz JG, Dugger BN, Shill HA, Caviness JN, Sabbagh MN, Beach TG, Arizona Parkinson Disease Consortium. Olfactory dysfunction in incidental Lewy body disease and Parkinson's disease. Parkinsonism Relat Disord. 2014 Nov; 20 (11):1260-2 Epub 2014 Aug 16 View PubMed Jacobson SA, Morshed T, Dugger BN, Beach TG, Hentz JG, Adler CH, Shill HA, Sabbagh MN, Belden CM, Sue LI, Caviness JN, Hu C, Arizona Parkinson's Disease Consortium. Plaques and tangles as well as Lewy-type alpha synucleinopathy are associated with formed visual hallucinations. 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A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014 May; 71 (5):543-52 View PubMed Dugger BN, Adler CH, Shill HA, Caviness J, Jacobson S, Driver-Dunckley E, Beach TG, Arizona Parkinson's Disease Consortium. Concomitant pathologies among a spectrum of parkinsonian disorders. Parkinsonism Relat Disord. 2014 May; 20 (5):525-9 Epub 2014 Feb 22 View PubMed Adler CH, Dugger BN, Hinni ML, Lott DG, Driver-Dunckley E, Hidalgo J, Henry-Watson J, Serrano G, Sue LI, Nagel T, Duffy A, Shill HA, Akiyama H, Walker DG, Beach TG. Submandibular gland needle biopsy for the diagnosis of Parkinson disease. Neurology. 2014 Mar 11; 82 (10):858-64 Epub 2014 Feb 05 View PubMed Dugger BN, Hentz JG, Adler CH, Sabbagh MN, Shill HA, Jacobson S, Caviness JN, Belden C, Driver-Dunckley E, Davis KJ, Sue LI, Beach TG. Clinicopathological outcomes of prospectively followed normal elderly brain bank volunteers. J Neuropathol Exp Neurol. 2014 Mar; 73 (3):244-52 View PubMed Lin TP, Adler CH, Hentz JG, Balcer LJ, Galetta SL, Devick S. Slowing of number naming speed by King-Devick test in Parkinson's disease. Parkinsonism Relat Disord. 2014 Feb; 20 (2):226-9 Epub 2013 Oct 18 View PubMed Siderowf A, Pontecorvo MJ, Shill HA, Mintun MA, Arora A, Joshi AD, Lu M, Adler CH, Galasko D, Liebsack C, Skovronsky DM, Sabbagh MN. PET imaging of amyloid with Florbetapir F 18 and PET imaging of dopamine degeneration with 18F-AV-133 (florbenazine) in patients with Alzheimer's disease and Lewy body disorders. BMC Neurology. 2014; 14(1):79. View PubMed Charles PD, Adler CH, Stacy M, Comella C, Jankovic J, Manack Adams A, Schwartz M, Brin MF. Cervical dystonia and pain: Characteristics and treatment patterns from CD PROBE (Cervical Dystonia Patient Registry for Observation of OnabotulinumtoxinA Efficacy). J Neurol. 2014; 261(7):1309-19. View PubMed Symanski C, Shill HA, Dugger B, Hentz JG, Adler CH, Jacobson SA, Driver-Dunckley E, Beach TG. Essential tremor is not associated with cerebellar Purkinje cell loss. Mov Disord. 2014; 29(4):496-500. View PubMed Burgos K, Malenica I, Metpally R, Courtright A, Rakela B, Beach T, Shill H, Adler C, Sabbagh M, Villa S, Tembe W, Craig D, Van Keuren-Jensen K. Profiles of extracellular miRNA in cerebrospinal fluid and serum from patients with Alzheimer's and Parkinson's diseases correlate with disease status and features of pathology. PLoS One. 2014; 9 (5):e94839 Epub 2014 May 05 View PubMed Halliday GM, Leverenz JB, Schneider JS, Adler CH. The neurobiological basis of cognitive impairment in Parkinson's disease. Mov Disord. 2014; 29(5):634-50. View PubMed Shill HA, Hentz JG, Jacobson SA, Belden C, Sabbagh MN, Beach TG, Driver-Dunckley E, Adler CH. Essential Tremor in the Elderly and Risk for Dementia. J Neurodegener Dis. 2014; 2014:328765 Epub 2014 Apr 09 View PubMed Shneyder N, Adler CH, Hentz JG, Shill H, Caviness JN, Sabbagh MN, Beach TG, Driver-Dunckley E. Autonomic complaints in patients with restless legs syndrome. Sleep Med. 2013 Dec; 14 (12):1413-6 Epub 2013 Sept 21 View PubMed Lewitt PA, Li J, Lu M, Beach TG, Adler CH, Guo L, Arizona Parkinson's Disease Consortium. 3-hydroxykynurenine and other Parkinson's disease biomarkers discovered by metabolomic analysis. Mov Disord. 2013 Oct; 28(12):1653-60. Epub 2013 Jul 19. View PubMed Kordower JH, Olanow CW, Dodiya HB, Chu Y, Beach TG, Adler CH, Halliday GM, Bartus RT. Disease duration and the integrity of the nigrostriatal system in Parkinson's disease. Brain. 2013 Aug; 136(Pt 8):2419-31. View PubMed Boeve BF, Silber MH, Ferman TJ, Lin SC, Benarroch EE, Schmeichel AM, Ahlskog JE, Caselli RJ, Jacobson S, Sabbagh M, Adler C, Woodruff B, Beach TG, Iranzo A, Gelpi E, Santamaria J, Tolosa E, Singer C, Mash DC, Luca C, Arnulf I, Duyckaerts C, Schenck CH, Mahowald MW, Dauvilliers Y, Graff-Radford NR, Wszolek ZK, Parisi JE, Dugger B, Murray ME, Dickson DW. Clinicopathologic correlations in 172 cases of rapid eye movement sleep behavior disorder with or without a coexisting neurologic disorder. Sleep Med. 2013 Aug; 14 (8):754-62 Epub 2013 Mar 07 View PubMed Mu L, Sobotka S, Chen J, Su H, Sanders I, Nyirenda T, Adler CH, Shill HA, Caviness JN, Samanta JE, Sue LI, Beach TG, the Arizona Parkinson's Disease Consortium. Parkinson disease affects peripheral sensory nerves in the pharynx. J Neuropathol Exp Neurol. 2013 Jul; 72(7):614-23. View PubMed Mu L, Sobotka S, Chen J, Su H, Sanders I, Adler CH, Shill HA, Caviness JN, Samanta JE, Beach TG, Arizona Parkinson's Disease Consortium. Alpha-synuclein pathology and axonal degeneration of the peripheral motor nerves innervating pharyngeal muscles in Parkinson disease. J Neuropathol Exp Neurol. 2013 Feb; 72(2):119-29. View PubMed Beach TG, Adler CH, Dugger BN, Serrano G, Hidalgo J, Henry-Watson J, Shill HA, Sue LI, Sabbagh MN, Akiyama H, Arizona Parkinson's Disease Consortium. Submandibular gland biopsy for the diagnosis of Parkinson disease. J Neuropathol Exp Neurol. 2013 Feb; 72(2):130-6. View PubMed Walker DG, Lue LF, Adler CH, Shill HA, Caviness JN, Sabbagh MN, Akiyama H, Serrano GE, Sue LI, Beach TG, Arizona Parkinson Disease Consortium. Changes in properties of serine 129 phosphorylated alpha-synuclein with progression of Lewy-type histopathology in human brains. Exp Neurol. 2013 Feb; 240:190-204. Epub 2012 Nov 28. View PubMed Malek-Ahmadi M, Kahlon V, Adler CH, Obradov A, Thind K, Shill HA, Sue LI, Caviness JN, Jacobson S, Sabbagh MN. Prevalence of Hippocampal Sclerosis in a Clinicopathologically Characterized Cohort. Clin Exp Med Sci. 2013; 1 (7):317-327 View PubMed Henderson-Smith A, Chow D, Meechoovet B, Aziz M, Jacobson SA, Shill HA, Sabbagh MN, Caviness JN, Adler CH, Driver-Dunckley ED, Beach TG, Yin H, Dunckley T. SMG1 identified as a regulator of Parkinson's disease-associated alpha-synuclein through siRNA screening. PLoS One. 2013; 8: (10)e77711. View PubMed Maarouf CL, Beach TG, Adler CH, Malek-Ahmadi M, Kokjohn TA, Dugger BN, Walker DG, Shill HA, Jacobson SA, Sabbagh MN, Roher AE, Arizona Parkinson's Disease Consortium. Quantitative appraisal of ventricular cerebrospinal fluid biomarkers in neuropathologically diagnosed Parkinson's disease cases lacking Alzheimer's disease pathology. Biomark Insights. 2013; 8:19-28 Epub 2013 Mar 12 View PubMed Damian A, Adler CH, Hentz JG, Shill HA, Caviness JN, Sabbagh MN, Evidente VG, Beach TG, Driver-Dunckley E. Autonomic function, as self-reported on the SCOPA-autonomic questionnaire, is normal in essential tremor but not in Parkinson's disease. Parkinsonism Relat Disord. 2012 Dec; 18: (10)1089-93. View PubMed Driver-Dunckley ED, Adler CH. Movement disorders and sleep. Neurol Clin. 2012 Nov; 30(4):1345-58. View PubMed Annerino DM, Arshad S, Taylor GM, Adler CH, Beach TG, Greene JG. Parkinson's disease is not associated with gastrointestinal myenteric ganglion neuron loss. Acta Neuropathol. 2012 Nov; 124(5):665-80. Epub 2012 Sep 02. View PubMed Lue LF, Walker DG, Adler CH, Shill H, Tran H, Akiyama H, Sue LI, Caviness J, Sabbagh MN, Beach TG. Biochemical increase in phosphorylated alpha-synuclein precedes histopathology of Lewy-type synucleinopathies. Brain Pathol. 2012 Nov; 22(6):745-56. Epub 2012 Apr 12. View PubMed Jiang H, He P, Adler CH, Shill H, Beach TG, Li R, Shen Y. Bid signal pathway components are identified in the temporal cortex with Parkinson disease. Neurology. 2012 Oct 23; 79(17):1767-73. Epub 2012 Sep 26. View PubMed Maarouf CL, Beach TG, Adler CH, Shill HA, Sabbagh MN, Wu T, Walker DG, Kokjohn TA, Roher AE, Arizona PD Consortium. Cerebrospinal fluid biomarkers of neuropathologically diagnosed Parkinson's disease subjects. Neurol Res. 2012 Sep; 34 (7):669-76 View PubMed Mu L, Sobotka S, Chen J, Su H, Sanders I, Adler CH, Shill HA, Caviness JN, Samanta JE, Beach TG, Arizona Parkinson's Disease Consortium. Altered pharyngeal muscles in Parkinson disease. J Neuropathol Exp Neurol. 2012 Jun; 71(6):520-30. View PubMed Litvan I, Goldman JG, Troster AI, Schmand BA, Weintraub D, Petersen RC, Mollenhauer B, Adler CH, Marder K, Williams-Gray CH, Aarsland D, Kulisevsky J, Rodriguez-Oroz MC, Burn DJ, Barker RA, Emre M. Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines. Mov Disord. 2012 Mar; 27(3):349-56. Epub 2012 Jan 24. View PubMed Dugger BN, Serrano GE, Sue LI, Walker DG, Adler CH, Shill HA, Sabbagh MN, Caviness JN, Hidalgo J, Saxon-Labelle M, Chiarolanza G, Mariner M, Henry-Watson J, Beach TG, the Arizona Parkinson's Disease Consortium. Presence of Striatal Amyloid Plaques in Parkinson's Disease Dementia Predicts Concomitant Alzheimer's Disease: Usefulness for Amyloid Imaging. J Parkinsons Dis. 2012 Jan 1; 2(1):57-65. View PubMed Shill HA, Adler CH, Beach TG. Pathology in essential tremor. Parkinsonism Relat Disord. 2012 Jan; 18 Suppl 1:S135-7. View PubMed Shill HA, Adler CH, Beach TG, Lue LF, Caviness JN, Sabbagh MN, Sue LI, Walker DG. Brain biochemistry in autopsied patients with essential tremor. Mov Disord. 2012 Jan; 27(1):113-7. Epub 2011 Oct 28. View PubMed Caviness JN, Adler CH, Hentz JG, Shill HA, Evidente VG, Driver-Dunckley ED, Sabbagh MN, Sue L, Beach TG. Incidental Lewy body disease: electrophysiological findings suggesting pre-clinical Lewy body disorders. Clin Neurophysiol. 2011 Dec; 122 (12):2426-32 Epub 2011 May 26 View PubMed Allen RP, Adler CH, Du W, Butcher A, Bregman DB, Earley CJ. Clinical efficacy and safety of IV ferric carboxymaltose (FCM) treatment of RLS: a multi-centred, placebo-controlled preliminary clinical trial. Sleep Med. 2011 Oct; 12(9):906-13. Epub 2011 Oct 05. View PubMed Adler CH, Crews D, Kahol K, Santello M, Noble B, Hentz JG, Caviness JN. Are the yips a task-specific dystonia or "golfer's cramp"? Mov Disord. 2011 Sep; 26 (11):1993-6 Epub 2011 June 14 View PubMed Evidente VG, Premkumar AP, Adler CH, Caviness JN, Driver-Dunckley E, Lyons MK. Medication dose reductions after pallidal versus subthalamic stimulation in patients with Parkinson's disease. Acta Neurol Scand. 2011 Sep; 124(3):211-4. Epub 2010 Oct 25. View PubMed Litvan I, Aarsland D, Adler CH, Goldman JG, Kulisevsky J, Mollenhauer B, Rodriguez-Oroz MC, Troster AI, Weintraub D. MDS Task Force on mild cognitive impairment in Parkinson's disease: critical review of PD-MCI. Mov Disord. 2011 Aug 15; 26(10):1814-24. Epub 2011 Jun 09. View PubMed Klassen BT, Hentz JG, Shill HA, Driver-Dunckley E, Evidente VG, Sabbagh MN, Adler CH, Caviness JN. Quantitative EEG as a predictive biomarker for Parkinson disease dementia. Neurology. 2011 Jul 12; 77 (2):118-24 Epub 2011 June 01 View PubMed Caviness JN, Lue LF, Beach TG, Hentz JG, Adler CH, Sue L, Sadeghi R, Driver-Dunckley E, Evidente VG, Sabbagh MN, Shill HA, Walker DG. Parkinson's disease, cortical dysfunction, and alpha-synuclein. Mov Disord. 2011 Jul; 26 (8):1436-42 Epub 2011 May 03 View PubMed Adler CH, Hentz JG, Shill HA, Sabbagh MN, Driver-Dunckley E, Evidente VG, Jacobson SA, Beach TG, Boeve B, Caviness JN. Probable RBD is increased in Parkinson's disease but not in essential tremor or restless legs syndrome. 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Olfactory bulb alpha -synucleinopathy has high specificity and sensitivity for Lewy body disorders. Acta Neuropathol (Berl). 2009 Feb; 117: (2)169-74. Lyons MK, Adler CH, Bansberg SF, Evidente VGH. Spasmodic dysphonia may respond to bilateral thalamic deep brain stimulation. Afr J of Neurol Sci. 2009; 28(1):10-811. Alvarez MV, Driver-Dunckley EE, Caviness JN, Adler CH, Evidente VG. Case series of painful legs and moving toes: clinical and electrophysiologic observations. Mov Disord. 2008 Oct 30; 23(14):2062-6. View PubMed Sparks DL, Ziolkowski C, Connor D, Beach T, Adler C, Sabbagh M. Copper and cognition in Alzheimer's disease and Parkinson's disease. Cell Biology & Toxicology. 2008 Oct; 24(5):426-30. Ludlow CL, Adler CH, Berke GS, Bielamowicz SA, Blitzer A, Bressman SB, Hallett M, Jinnah HA, Juergens U, Martin SB, Perlmutter JS, Sapienza C, Singleton A, Tanner CM, Woodson GE. Research priorities in spasmodic dysphonia. Otolaryngol Head Neck Surg. 2008 Oct; 139(4):495-505. View PubMed Beach TG, White CL, Hamilton RL, Duda JE, Iwatsubo T, Dickson DW, Leverenz JB, Roncaroli F, Buttini M, Hladik CL, Sue LI, Noorigian JV, Adler CH. Evaluation of alpha-synuclein immunohistochemical methods used by invited experts. Acta Neuropathol. 2008 Sep; 116(3):277-88. Epub 2008 Jul 15. View PubMed Stamper C, Siegel A, Liang WS, Pearson JV, Stephan DA, Shill H, Connor D, Caviness JN, Sabbagh M, Beach TG, Adler CH, Dunckley T. Neuronal gene expression correlates of Parkinson's disease with dementia. Mov Disord. 2008 Aug 15; 23(11):1588-95. View PubMed Ross OA, Braithwaite AT, Skipper LM, Kachergus J, Hulihan MM, Middleton FA, Nishioka K, Fuchs J, Gasser T, Maraganore DM, Adler CH, Larvor L, Chartier-Harlin MC, Nilsson C, Langston JW, Gwinn K, Hattori N, Farrer MJ. Genomic investigation of alpha-synuclein multiplication and parkinsonism. Ann Neurol. 2008 Jun; 63 (6):743-50 View PubMed Shill HA, Adler CH, Sabbagh MN, Connor DJ, Caviness JN, Hentz JG, Beach TG. Pathologic findings in prospectively ascertained essential tremor subjects. Neurology. 2008 Apr 15; 70(16 Pt 2):1452-5. View PubMed Goetz CG, Wuu J, McDermott MP, Adler CH, Fahn S, Freed CR, Hauser RA, Olanow WC, Shoulson I, Tandon PK, Parkinson Study Group, Leurgans S. Placebo response in Parkinson's disease: comparisons among 11 trials covering medical and surgical interventions. Mov Disord. 2008 Apr 15; 23(5):690-9. View PubMed Beach TG, Adler CH, Sue LI, Peirce JB, Bachalakuri J, Dalsing-Hernandez JE, Lue LF, Caviness JN, Connor DJ, Sabbagh MN, Walker DG. Reduced striatal tyrosine hydroxylase in incidental Lewy body disease. Acta Neuropathol. 2008 Apr; 115(4):445-51. Epub 2007 Nov 06. View PubMed McKinnon JH, Demaerschalk BM, Caviness JN, Wellik KE, Adler CH, Wingerchuk DM. Sniffing out Parkinson disease: can olfactory testing differentiate parkinsonian disorders? Neurologist. 2007 Nov; 13(6):382-5. View PubMed Beach TG, Sue LI, Walker DG, Lue LF, Connor DJ, Caviness JN, Sabbagh MN, Adler CH. Marked microglial reaction in normal aging human substantia nigra: correlation with extraneuronal neuromelanin pigment deposits. Acta Neuropathol (Berl). 2007 Oct; 114: (4)419-24. View PubMed Driver-Dunckley ED, Noble BN, Hentz JG, Evidente VG, Caviness JN, Parish J, Krahn L, Adler CH. Gambling and increased sexual desire with dopaminergic medications in restless legs syndrome. Clin Neuropharmacol. 2007 Sep-Oct; 30 (5):249-55 View PubMed Caviness JN, Hentz JG, Evidente VG, Driver-Dunckley E, Samanta J, Mahant P, Connor DJ, Sabbagh MN, Shill HA, Adler CH. Both early and late cognitive dysfunction affects the electroencephalogram in Parkinson's disease. Parkinsonism Relat Disord. 2007 Aug; 13: (6)348-54. View PubMed Trosch RM, Adler CH, Pappert EJ. Botulinum toxin type B (Myobloc(R)) in subjects with hemifacial spasm: Results from an open-label, dose-escalation safety study. Mov Disord. 2007 Jul 15; 22(9):1258-64. View PubMed Caviness JN, Driver-Dunckley E, Connor DJ, Sabbagh MN, Hentz JG, Noble B, Evidente VG, Shill HA, Adler CH. Defining mild cognitive impairment in Parkinson's disease. Mov Disord. 2007 Jul 15; 22 (9):1272-7 View PubMed Snyder CH, Adler CH. The patient with Parkinson's disease: part I-treating the motor symptoms; part II-treating the nonmotor symptoms. J Am Acad Nurse Pract. 2007 Apr; 19(4):179-97. View PubMed Melquist S, Craig DW, Huentelman MJ, Crook R, Pearson JV, Baker M, Zismann VL, Gass J, Adamson J, Szelinger S, Corneveaux J, Cannon A, Coon KD, Lincoln S, Adler C, Tuite P, Calne DB, Bigio EH, Uitti RJ, Wszolek ZK, Golbe LI, Caselli RJ, Graff-Radford N, Litvan I, Farrer MJ, Dickson DW, Hutton M, Stephan DA. Identification of a novel risk locus for progressive supranuclear palsy by a pooled genomewide scan of 500,288 single-nucleotide polymorphisms. 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Predictors of diagnosis in Huntington disease. Neurology. 2007; 68(20):1710-7. Sabbagh MN, Lahti T, Connor DJ, Caviness JN, Shill H, Vedders L, Mahant P, Samanta J, Burns RS, Evidente VG, Driver-Dunckley E, Reisberg B, Bircea S, Adler CH. Functional ability correlates with cognitive impairment in Parkinson's disease and Alzheimer's disease. Dement Geriatr Cogn Disord. 2007; 24: (5)327-34. View PubMed Jankovic J, Hunter C, Dolimbek BZ, Dolimbek GS, Adler CH, Brashear A, Comella CL, Gordon M, Riley DE, Sethi K, Singer C, Stacy M, Tarsy D, Atassi MZ. Clinico-immunologic aspects of botulinum toxin type B treatment of cervical dystonia. Neurology. 2006 Dec 26; 67(12):2233-5. View PubMed Driver-Dunckley E, Evidente VG, Adler CH, Hillman R, Hernandez J, Fletcher G, Lyons MK. Restless legs syndrome in Parkinson's disease patients may improve with subthalamic stimulation. 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Neurology. 2005 Nov 8; 65(9):1423-9. View PubMed Thorpy MJ, Adler CH. Parkinson's disease and sleep. Neurol Clin. 2005 Nov; 23(4):1187-208. View PubMed Sabbagh MN, Silverberg N, Bircea S, Majeed B, Samant S, Caviness JN, Reisberg B, Adler CH. Is the functional decline of Parkinson's disease similar to the functional decline of Alzheimer's disease? Parkinsonism Relat Disord. 2005 Aug; 11(5):311-5. View PubMed Adler CH, Thorpy MJ. Sleep issues in Parkinson's disease. Neurology. 2005 Jun 28; 64 (12 Suppl 3):S12-20 View PubMed Wunderlich GR, Evans KR, Sills T, Pollentier S, Reess J, Allen RP, Hening W, Walter AS. An item response analysis of the international restless legs syndrome study group rating scale for restless legs syndrome. Sleep med. 2005 Mar; 6(2):131-9. Toft M, Aasly J, Bisceglio G, Adler CH, Uitti RJ, Krygowska-Wajs A, Lynch T, Wszolek ZK, Farrer MJ. Parkinsonism, FXTAS, and FMR1 premutations. Mov Disord. 2005 Feb; 20(2):230-3. View PubMed Adler CH. Nonmotor complications in Parkinson's disease. Mov Disord. 2005; 20 Suppl 11:S23-9 View PubMed Fahn S, Oakes D, Shoulson I, Kieburtz K, Rudolph A, Lang A, Olanow CW, Tanner C, Marek K, Parkinson Study Group. Levodopa and the progression of Parkinson's disease. N Engl J Med. 2004 Dec 9; 351 (24):2498-508 View PubMed Adler CH, Bansberg SF, Hentz JG, Ramig LO, Buder EH, Witt K, Edwards BW, Krein-Jones K, Caviness JN. Botulinum toxin type A for treating voice tremor. Arch Neurol. 2004 Sep; 61(9):1416-20. View PubMed Adler CH, Bansberg SF, Krein-Jones K, Hentz JG. Safety and efficacy of botulinum toxin type B (Myobloc) in adductor spasmodic dysphonia. Mov Disord. 2004 Sep; 19(9):1075-9. View PubMed Pittock SJ, Parrett T, Adler CH, Parisi JE, Dickson DW, Ahlskog JE. Neuropathology of primary restless leg syndrome: absence of specific tau- and alpha-synuclein pathology. Mov Disord. 2004 Jun; 19(6):695-9. View PubMed Adler CH, Hauser RA, Sethi K, Caviness JN, Marlor L, Anderson WM, Hentz JG. Ropinirole for restless legs syndrome: a placebo-controlled crossover trial. Neurology. 2004 Apr 27; 62 (8):1405-7 View PubMed Van Gemmert AWA, Adler CH, Stelmach GE. Parkinson's disease patients undershoot target size in handwriting and similar tasks. Journal of Neurology, Neurosurgery & Psychiatry. 2003 Nov; 74(11):1502-8. View PubMed Singleton AB, Farrer M, Johnson J, Singleton A, Hague S, Kachergus J, Hulihan M, Peuralinna T, Dutra A, Nussbaum R, Lincoln S, Crawley A, Hanson M, Maraganore D, Adler C, Cookson MR, Muenter M, Baptista M, Miller D, Blancato J, Hardy J, Gwinn-Hardy K. alpha-Synuclein locus triplication causes Parkinson's disease. Science. 2003 Oct 31; 302(5646):841. View PubMed Caviness JN, Adler CH, Sabbagh MN, Connor DJ, Hernandez JL, Lagerlund TD. Abnormal corticomuscular coherence is associated with the small amplitude cortical myoclonus in Parkinson's disease. Mov Disord. 2003 Oct; 18(10):1157-62. View PubMed Evidente VG, Caviness JN, Adler CH. Case studies in movement disorders. Semin Neurol. 2003 Sep; 23(3):277-84. View PubMed Beach TG, Sue L, Scott S, Layne K, Newell A, Walker D, Baker M, Sahara N, Yen SH, Hutton M, Caselli R, Adler C, Connor D, Sabbagh M. Hippocampal sclerosis dementia with tauopathy. Brain Pathol. 2003 Jul; 13(3):263-78. View PubMed Romero DH, Van Gemmert AWA, Adler CH, Bekkering H, Stelmach GE. Altered aiming movements in Parkinson's disease patients and elderly adults as a function of delays in movement onset. Exp Brain Res. 2003 Jul; 151(2):249-61. View PubMed Romero DH, Van Gemmert AWA, Adler CH, Bekkering H, Stelmach GE. Time delays prior to movement alter the drawing kinematics of elderly adults. Human Movement Science. 2003 Apr; 22(2):207-20. View PubMed Adler CH, Caviness JN, Hentz JG, Lind M, Tiede J. Randomized trial of modafinil for treating subjective daytime sleepiness in patients with Parkinson's disease. Mov Disord. 2003 Mar; 18 (3):287-293 View PubMed Comella CL, Leurgans S, Wuu J, Stebbins GT, Chmura T, The Dystonia Study Group. Rating scales for dystonia: A multicenter assessment. Mov Disorders. 2003; 18:303-12. Allen RP, Picchietti D, Hening WA, Trenkwalder C, Walters AS, Montlaisir J, the participants in the RLS Diagnosis Epidemiology workshop at the NIH, in collaboration with members of the International RLS Study Group. Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health Sleep Medicine. 2003; 4:101-19. Adler CH, Thorpy MJ. Awake and Involved: Addressing excessive daytime sleepiness in patients with Parkinson's disease, Overview of Parkinson's disease (Review Article). The Treatment Reporter Neurology. 2003(Part 1). Thorpy MJ, Adler CH. Awake and Involved: Addressing excessive daytime sleepiness in patients with Parkinson's disease, Sleep issues in Parkinson's disease (Review Article). The Treatment Reporter Neurology. 2003; Part 2. Smith AM, Adler CH, Crews D, Wharen RE, Laskowski ER, Barnes K, Valone Bell C, Pelz D, Brennan RD, Smith J, Sorenson MC, Kaufman KR. The 'yips' in golf: a continuum between a focal dystonia and choking. Sports Med. 2003; 33 (1):13-31 View PubMed Contreras-Vidal JL, Teulings HL, Stelmach GE, Adler CH. Adaptation to changes in vertical display gain during handwriting in Parkinson's disease patients, elderly and young controls. Parkinsonism & Related Disorders. 2002 Dec; 9(2):77-84. View PubMed Adler CH, Hentz JG, Joyce JN, Beach T, Caviness JN. Motor impairment in normal aging, clinically possible Parkinson's disease, and clinically probable Parkinson's disease: longitudinal evaluation of a cohort of prospective brain donors. Parkinsonism Relat Disord. 2002 Dec; 9 (2):103-10 View PubMed Liss JM, Spitzer SM, Caviness JN, Adler C. The effects of familiarization on intelligibility and lexical segmentation in hypokinetic and ataxic dysarthria. J Acoust Soc Am. 2002 Dec; 112(6):3022-30. View PubMed Parkinson Study Group. A controlled trial of rasagiline in early Parkinson disease: the TEMPO Study. Arch Neurol. 2002 Dec; 59 (12):1937-43 View PubMed Joyce JN, Ryoo HL, Beach TB, Caviness JN, Stacy M, Gurevich EV, Reiser M, Adler CH. Loss of response to levodopa in Parkinson's disease and co-occurrence with dementia: role of D-3 and not D-2 receptors. Brain Res. 2002 Nov 15; 955(1-2):138-52. View PubMed Korczyn AD, Thalamas C, Adler CH. Dosing with ropinirole in a clinical setting. Acta Neurol Scand. 2002 Oct; 106(4):200-4. View PubMed Caviness JN, Adler CH, Beach TG, Wetjen KL, Caselli RJ. Small-amplitude cortical myoclonus in Parkinson's disease: Physiology and clinical observations. Mov Disord. 2002 Jul; 17(4):657-62. View PubMed Kompoliti K, Adler CH, Raman R, Pincus JH, Leibowitz MT, Ferry JJ, Blasucci L, Caviness JN, Leurgans S, Chase WM, Yones LC, Tan E, Carvey P, Goetz CG. Gender and pramipexole effects on levodopa pharmacokinetics and pharmacodynamics. Neurology. 2002 May 14; 58(9):1418-22. View PubMed Vernino S, Tuite P, Adler CH, Meschia JF, Boeve BF, Boasberg P, Parisi JE, Lennon VA. Paraneoplastic chorea associated with CRMP-5 neuronal antibody and lung carcinoma. Ann Neurol. 2002 May; 51(5):625-30. View PubMed Teulings HL, Contreras-Vidal JL, Stelmach GE, Adler CH. Adaptation of handwriting size under distorted visual feedback in patients with Parkinson's disease and elderly and young controls. Journal of Neurology, Neurosurgery & Psychiatry.. 2002 Mar; 72: (3)315-24. View PubMed Adler CH. Relevance of motor complications in Parkinson's disease. Neurology. 2002 Feb 26; 58 (4 Suppl 1):S51-6 View PubMed Adler CH, Factor SA, Brin M, Sethi KD. Secondary nonresponsiveness to botulinum toxin type A in patients with oromandibular dystonia. Mov Disord. 2002 Jan; 17 (1):158-61 View PubMed Caviness JN, Smith BE, Clarke Stevens J, Stevens JC, Adler CH, Caselli RJ, Hentz JG, Manfred MS, Muenter D. Motor unit number estimates in idiopathic Parkinson's disease. Parkinsonism Relat Disord. 2002 Jan; 8 (3):161-4 View PubMed Adler CH. Diagnosing and treating restless legs syndrome. Women's Health Orthopedic Edition. 2002; 5:54-8. Caviness JN, Adler CH, Beach TG, Wetjen KL, Caselli RJ. Myoclonus in Lewy body disorders. Adv Neurol. 2002; 89:23-30. View PubMed Adler CH, Joyce JN. Collaboration Amongst Arizona Parkinson's Disease Research Centers-Parkinson's Disease Center Without Walls (Review Article). AZ Parkinson's Disease Report. 2002. Adler CH. Managing movement disorders with botulinum toxins: An effective approach for dystonia, tics, tremor, and hemifacial spasm (Review Article). Women's Health in Primary Care. 2002; 5:707-19. Evidente VG, Evidente VG, Caviness JN, Adler CH, Gwinn-Hardy KA, Pratley RE. Serum leptin concentrations and satiety in Parkinson's disease patients with and without weight loss. Mov Disord. 2001 Sep; 16 (5):924-7 View PubMed Joyce JN, Ryoo H, Gurevich EV, Adler C, Beach T. Ventral striatal D(3) receptors and Parkinson's Disease. Parkinsonism Relat Disord. 2001 Jul; 7(3):225-230. View PubMed Brin MF, Lyons KE, Doucette J, Adler CH, Caviness JN, Comella CL, Dubinsky RM, Friedman JH, Manyam BV, Matsumoto JY, Pullman SL, Rajput AH, Sethi KD, Tanner C, Koller WC. A randomized, double masked, controlled trial of botulinum toxin type A in essential hand tremor. Neurology. 2001 Jun 12; 56(11):1523-8. View PubMed Alberts JL, Adler CH, Saling M, Stelmach GE. Prehension patterns in restless legs syndrome patients. Parkinsonism & Related Disorders. 2001 Apr; 7(2):143-148. View PubMed Shoulson I, Penney J, McDermott M, Schwid S, Kayson E, Chase T, Fahn S, Greenamyre JT, Lang A, Siderowf A, Pearson N, Harrison M, Rost E, Colcher A, Lloyd M, Matthews M, Pahwa R, McGuire D, Lew MF, Schuman S, Marek K, Broshjeit S, Factor S, Brown D, Feigin A, Mazurkiewicz J, Ford B, Jennings D, Dilllon S, Comella C, Blasucci L, Janko K, Shulman L, Wiener W, Bateman-Rodriguez D, Carrion A, Suchowersky O, Lafontaine AL, Pantella C, Siemers E, Belden J, Davies R, Lannon M, Grimes D, Gray P, Martin W, Kennedy L, Adler C, Newman S, Hammerstad J, Stone C, Lewitt P, Bardram K, Mistura K, Miyasaki J, Johnston L, Cha JH, Tennis M, Panniset M, Hall J, Tetrud J, Friedlander J, Hauser R, Gauger L, Rodnitzky R, Deleo A, Dobson J, Seeberger L, Dingmann C, Tarsy D, Ryan P, Elmer L, Ruzicka D, Stacy M, Brewer M, Locke B, Baker D, Casaceli C, Day D, Florack M, Hodgeman K, Laroia N, Nobel R, Orme C, Rexo L, Rothenburgh K, Sulimowicz K, Watts A, Wratni E, Tariot P, Cox C, Leventhal C, Alderfer V, Craun AM, Frey J, McCree L, McDermott J, Cooper J, Holdich T, Read B, Parkinson Study Group. A randomized, controlled trial of remacemide for motor fluctuations in Parkinson's disease. Neurology. 2001 Feb 27; 56(4):455-62. View PubMed Caviness JN, Smith BE, Stevens JC, Adler CH, Caselli RJ, Hentz JG, Muenter MD. Motor Unit Number Estimates in Idiopathic Parkinson's Disease. Parkinsonism and Related Disorders. 2001; 8:161-4. Adler CH. Ten commonly asked questions about initiating treatment for Parkinson's disease (Review Article). The Neurologist. 2001; 7(3):188-92. Adler CH. Diagnosing and treating restless legs syndrome (Review Article). Women's Health In Primary Care. 2001; 4:224-8. Adler CH. Diagnosing and treating restless legs syndrome (Review Article). Women's Health Gynecology Edition. 2001; 1:371-8. Pennachio DL, Consultants. Parkinson's disease: Progress along the continuum of care (Review Article). Patient Care. 2000 Dec. Adler CH. Questions and answers about clinical trials (Review Article). Nightwalkers: Restless Legs Syndrome Newsletter. 2000 Nov. Alberts JL, Saling M, Adler CH, Stelmach GE. Disruptions in the reach-to-grasp actions of Parkinson's patients. Exp Brain Res. 2000 Oct; 134(3):353-62. View PubMed Adler CH. Strategies for controlling dystonia. Overview of therapies that may alleviate symptoms. Postgrad Med. 2000 Oct; 108 (5):151-2, 155-6, 159-60 View PubMed Cooper C, Evidente VG, Hentz JG, Evidente VG, Adler CH, Caviness JN, Gwinn-Hardy K. The effect of temperature on hand function in patients with tremor. J Hand Ther. 2000 Oct-Dec; 13 (4):276-88 View PubMed Liss JM, Spitzer SM, Caviness JN, Adler C, Edwards BW. Lexical boundary error analysis in hypokinetic and ataxic dysarthria. J Acoust Soc Am. 2000 Jun; 107(6):3415-24. View PubMed Gwinn-Hardy KA, Adler CH, Weaver AL, Fish NM, Newman SJ. Effect of hormone variations and other factors on symptom severity in women with dystonia. Mayo Clin Proc. 2000 Mar; 75(3):235-40. View PubMed Evidente VG, Evidente VG, Adler CH, Caviness JN, Hentz JG, Gwinn-Hardy K. Amantadine is beneficial in restless legs syndrome. Mov Disord. 2000 Mar; 15 (2):324-7 View PubMed Caviness JN, Smith BE, Stevens JC, Adler CH, Caselli RJ, Reiners CA, Hentz JG, Muenter MD. Motor unit changes in sporadic idiopathic Parkinson's disease. Mov Disord. 2000 Mar; 15 (2):238-43 View PubMed Hauser RA, Friedlander J, Zesiewicz TA, Adler CH, Seeberger LC, O'Brien CF, Molho ES, Factor SA. A home diary to assess functional status in patients with Parkinson's disease with motor fluctuations and dyskinesia. Clin Neuropharmacol. 2000 Mar-Apr; 23(2):75-81. View PubMed Gwinn-Hardy KA, Crook R, Lincoln S, Adler CH, Caviness JN, Hardy J, Farrer M. A kindred with Parkinson's disease not showing genetic linkage to established loci. Neurology. 2000 Jan 25; 54(2):504-7. View PubMed Adler CH, Kumar R. Pharmacological and surgical options for the treatment of cervical dystonia. Neurology. 2000; 55(12 Suppl 5):S9-14. View PubMed Caviness JN, Gwinn-Hardy K, Adler CH, Muenter MD. Electrophysiological observations in hereditary parkinsonism-dementia with Lewy body pathology. Mov Disord. 2000 Jan; 15 (1):140-5 View PubMed Spitzer SM, Liss JM, Caviness JN, Adler C. The effects of familiarization on listener perception of hypokinetic and ataxic dysarthric speech. Journal of Medical Speech-Language Pathology. 2000; 8:285-93. Joyce JN, Adler CH. Research for new treatment of Parkinson's disease (Review Article). Southwest Parkinson Report. 2000 Spr/Sum. Adler CH. Review of New-Onset Tic Disorders in Adults (Review Article). Journal Watch Neurology. 2000; 2:73-4. Brin MF, Lew MF, Adler CH, Comella CL, Factor SA, Jankovic J, O'Brien C, Murray JJ, Wallace JD, Willmer-Hulme A, Koller M. Safety and efficacy of NeuroBloc (botulinum toxin type B) in type A-resistant cervical dystonia. Neurology. 1999 Oct 22; 53(7):1431-8. View PubMed Weiss PH, Stelmach GE, Chaiken A, Adler CH. Use of advance information for complex movements in Parkinson's disease. Parkinsonism & Related Disorders. 1999 Apr-May; 5(1-2):19-25. Evidente VG, Adler CH. How to help patients with restless legs syndrome. Discerning the indescribable and relaxing the restless. Postgrad Med. 1999 Mar; 105: (3)59-61, 65-6, 73-4. View PubMed Adler CH. Differential diagnosis of Parkinson's disease. Med Clin North Am. 1999 Mar; 83 (2):349-67 View PubMed Farrer M, Gwinn-Hardy K, Muenter M, DeVrieze FW, Crook R, Perez-Tur J, Lincoln S, Maraganore D, Adler C, Newman S, MacElwee K, McCarthy P, Miller C, Waters C, Hardy J. A chromosome 4p haplotype segregating with Parkinson's disease and postural tremor. Hum Mol Genet. 1999 Jan; 8(1):81-5. View PubMed Evidente VG, Evidente VG, Adler CH, Caviness JN, Gwinn-Hardy K. A pilot study on the motor effects of rimantadine in Parkinson's disease. Clin Neuropharmacol. 1999 Jan-Feb; 22 (1):30-2 View PubMed Liss JM, Spitzer S, Caviness JN, Adler C, Edwards B. Syllabic strength and lexical boundary decisions in the perception of hypokinetic dysarthric speech. J Acoust Soc Am. 1998 Oct; 104(4):2457-66. View PubMed Adler CH. Botulinum toxin: Overview and use in tremor disorders (Review Article). International Tremor Foundation Newsletter. 1998 Oct. Sethi KD, Obrien CF, Hammerstad JP, Adler CH, Davis TL, Taylor RL, Sanchezramos J, Bertoni JM, Hauser RA. Ropinirole for the treatment of early Parkinson-disease - a 12-month experience. Arch Neurol. 1998 Sep; 55(9):1211-1216. View PubMed Evidente VG, Adler CH, Caviness JN, Gwinn KA. Effective treatment of orthostatic tremor with gabapentin. Mov Disord. 1998 Sep; 13 (5):829-31 View PubMed Adler CH, Singer C, O'Brien C, Hauser RA, Lew MF, Marek KL, Dorflinger E, Pedder S, Deptula D, Yoo K. Randomized, placebo-controlled study of tolcapone in patients with fluctuating Parkinson disease treated with levodopa-carbidopa. Tolcapone Fluctuator Study Group III. Arch Neurol. 1998 Aug; 55 (8):1089-95 View PubMed Kurth MC, Adler CH. COMT inhibition: a new treatment strategy for Parkinson's disease. Neurology. 1998 May; 50(5 Suppl 5):S3-14. View PubMed Caviness JN, Adler CH, Newman S, Caselli RJ, Muenter MD. Cortical myoclonus in levodopa-responsive parkinsonism. Mov Disord. 1998 May; 13(3):540-4. View PubMed Johnstone SJ, Adler CH. Headache and facial pain responsive to botulinum toxin: an unusual presentation of blepharospasm. Headache. 1998 May; 38(5):366-8. View PubMed Adler CH, Gwinn KA, Newman S. Olfactory function in restless legs syndrome. Mov Disord. 1998 May; 13(3):563-5. View PubMed Evidente VG, Adler CH, Giannini C, Conley CR, Parisi JE, Fletcher GP. Erdheim-Chester disease with extensive intraaxial brain stem lesions presenting as a progressive cerebellar syndrome. Mov Disord. 1998 May; 13(3):576-81. View PubMed Shannon KM, Penn RD, Kroin JS, Adler CH, Janko KA, York M, Cox SJ. Stereotactic pallidotomy for the treatment of Parkinson's disease. Efficacy and adverse effects at 6 months in 26 patients. Neurology. 1998 Feb; 50(2):434-8. View PubMed Adler CH. COMT inhibitors: novel treatments for Parkinson's disease. CNS Spectrums. 1998; 3(2):53-56. Evidente VG, Adler CH. Hemifacial spasm and other craniofacial movement disorders. Mayo Clin Proc. 1998 Jan; 73(1):67-71. View PubMed Johnstone S, Adler CH. Headache and facial pain: Response to botulinum toxin (Review Article). Benign Essential Blepharospasm Newsletter. 1998; 17(5):5. Tresilian JR, Stelmach GE, Adler CH. Stability of reach-to-grasp movement patterns in Parkinson's disease. Brain. 1997 Nov; 120(Pt 11):2093-111. View PubMed Uitti RJ, Wharen RE Jr, Turk MF, Lucas JA, Finton MJ, Graff-Radford NR, Boylan KB, Goerss SJ, Kall BA, Adler CH, Caviness JN, Atkinson EJ. Unilateral pallidotomy for Parkinson's disease: comparison of outcome in younger versus elderly patients. Neurology. 1997 Oct; 49 (4):1072-7 View PubMed Adler CH, Sethi KD, Hauser RA, Davis TL, Hammerstad JP, Bertoni J, Taylor RL, Sanchez-Ramos J, O'Brien CF. Ropinirole for the treatment of early Parkinson's disease. The Ropinirole Study Group. Neurology. 1997 Aug; 49 (2):393-9 View PubMed Teulings HL, Contreras-Vidal JL, Stelmach GE, Adler CH. Parkinsonism reduces coordination of fingers, wrist, and arm in fine motor control. Exp Neurol. 1997 Jul; 146(1):159-70. View PubMed O'Neill MA, Gwinn KA, Adler CH. Biofeedback for writer's cramp. Am J Occup Ther. 1997 Jul-Aug; 51 (7):605-7 View PubMed Evidente VGH, Adler CH. Pharmacologic options for managing Parkinson's-disease. Hosp Formul. 1997 Jun; 32(6):594-610. Adler CH, Caviness JN. Dystonia secondary to electrical injury: surface electromyographic evaluation and implications for the organicity of the condition. J Neurol Sci. 1997 May 29; 148 (2):187-92 View PubMed Adler CH. Treatment of restless legs syndrome with gabapentin. Clin Neuropharmacol. 1997 Apr; 20 (2):148-51 View PubMed Kurth MC, Adler CH, Sthilaire M, Singer C, Waters C, Lewitt P, Chernik DA, Dorflinger EE, Yoo K, Lieberman AN, Brewer M, Sainthilaire M, Pery LM, Thomas C, Turpin L, Obrien CF, Seeberger LC, Duncan KL, Caviness JN, Douglas M, Wheeler K, Riley D, Rainey P, Tanner CM, Kelker K, et al. Tolcapone improves motor function and reduces levodopa requirement in patients with Parkinson's disease experiencing motor fluctuations - a multicenter, double blind, randomized, placebo-controlled trial. Neurology. 1997 Jan; 48(1):81-87. View PubMed Evidente V, Adler CH. Current management of Parkinson's disease. Formulary. 1997; 32:594-610. Adler CH, Joyce J. Parkinson's disease and your brain (Review Article). Arizona Parkinson Report Summer,. 1997; Lieberman A, Caviness JN, The Pramipexole Study Group. Clinical evaluation of pramipexole in advanced Parkinson's disease: Results of a double-blind, placebo-controled, parallel-group study. Neurology. 1997; 49(162-8). Weiss P, Stelmach GE, Adler CH, Waterman C. Parkinsonian arm movements as altered by task difficulty. Parkinsonism Relat Disord. 1996 Oct; 2 (4):215-23 View PubMed Ahlskog JE, Wright KF, Muenter MD, Adler CH. Adjunctive cabergoline therapy of Parkinson's disease: comparison with placebo and assessment of dose responses and duration of effect. Clin Neuropharmacol. 1996 Jun; 19 (3):202-12 View PubMed Hutton JT, Koller WC, Ahlskog JE, Pahwa R, Hurtig HI, Stern MB, Hiner BC, Lieberman A, Pfeiffer RF, Rodnitzky RL, Waters CH, Muenter MD, Adler CH, Morris JL. Multicenter, placebo-controlled trial of cabergoline taken once daily in the treatment of Parkinson's disease. Neurology. 1996 Apr; 46(4):1062-5. View PubMed Adler CH, Zimmerman RS, Lyons MK, Simeone F, Brin MF. Perioperative use of botulinum toxin for movement disorder-induced cervical spine disease. Mov Disord. 1996 Jan; 11(1):79-81. View PubMed Adler CH, Wrabetz LG. Lesch-Nyhan variant: Dystonia, ataxia, near-normal intelligence, and no self-mutilation. Movement Disorders. 1996; 11:583-4. View PubMed Adler CH, Stern MB, Shils J, Stecker MM. Movement analysis in generalized and hemiparkinsonism. J Human Movement Studies. 1995; 29:51-62. Adler CH. Why? I don't know! (Review Article). NSTA Newsletter 4. 1995; 12: (1) Pestronk A, Choksi R, Bieser K, Goldstein JM, Adler CH, Caselli RJ, George EB. Treatable gait disorder and polyneuropathy associated with high titer serum IgM binding to antigens that copurify with myelin-associated glycoprotein. Muscle & Nerve. 1994 Nov; 17(11):1293-300. View PubMed Adler CH, Wrabetz L, Brin MF, Hurtig HI. Cerebellar ataxia, dystonia, and tremor within a family: variable phenotypes of a single genetic disorder? Mov Disord. 1994 Mar; 9(2):155-60. View PubMed Stern MB, Doty RL, Dotti M, Corcoran P, Crawford D, McKeown DA, Adler CH, Gollomp S, Hurtig H. Olfactory function in Parkinson's disease subtypes. Neurology. 1994; 44:266-8. View PubMed Bennett KMB, Adler CH, Stelmach GE, Castiello U. A kinematic study of the reach to grasp movement in a patient with hemi-Parkinson disease. Neuropsychologia. 1993; 31:709-716. View PubMed Castiello U, Bennett KMB, Adler CH, Stelmach GE. Perturbation of the grasp component of a prehension movement in a patient with hemi-Parkinson disease. Neuropsychologia. 1993; 31:717-723. View PubMed Bernardi B, Zimmerman RA, Savino PJ, Adler C. Magnetic resonance tomographic angiography in the investigation of hemifacial spasm. Neuroradiology. 1993; 35(8):606-11. View PubMed Adler CH. Mechanism of action of botulinum toxin (Review Article). NSTA Newsletter 4. 1993; 10: (2) Adler CH, Zimmerman RA, Savino PJ, Bernardi B, Bosley TM, Sergott RC. Hemifacial spasm: evaluation by magnetic resonance imaging and magnetic resonance tomographic angiography. Ann Neurol. 1992 Oct; 32(4):502-6. View PubMed Dodick D, Adler CH. Tourette's syndrome. Current approaches to recognition and management. Postgrad Med. 1992 Oct; 92 (5):299-302, 305-8 View PubMed Adler CH, Hurtig HI, Jacobson MP, Brooks ML. CPC: a woman with lung and brain masses. J Neuroimaging. 1992; 2:97-101. Arai H, Schmidt ML, Lee VMY, Hurtig HI, Greenberg BD, Adler CH, Trojanowski JQ. Epitope analysis of senile plaque components in the hippocampus. Neurology. 1992; 42:1315-1322. View PubMed Adler CH. Dystonia, clinical overview. Clin Semin Mov Disord. 1992; 1:14-16. Adler CH. Botulinum toxin A therapy in dystonia. Hosp Pract (Off Ed). 1991 Aug 15; 26 (8):35, 38, 41-2 View PubMed Adler CH, Galetta SL. Oculo-facial-skeletal myorhythmia in Whipple disease: treatment with ceftriaxone. Ann Intern Med. 1990 Mar 15; 112(6):467-9. View PubMed Adler CH, Stern MB, Brooks ML. Parkinsonism secondary to bilateral striatal fungal abscesses. Mov Disord. 1989; 4(4):333-7. View PubMed Adler CH, Meller E, Goldstein M. Receptor reserve at functional alpha-2 adrenergic autoreceptors in the rat cerebral cortex. J Pharmacol Exp Ther. 1987; 240:508-515. View PubMed Meller E, Helmer-Matyjek E, Bohmaker K, Adler CH, Friedhoff AJ, Goldstein M. Receptor reserve at striatal dopamine autoreceptors: implications for selectivity of dopamine agonists. Eur J Pharmacol. 1986 Apr 16; 123(2):311-4. View PubMed Goldstein M, Kusano N, Adler C, Meller E. Characterization of central neuropeptide Y receptor binding sites and possible interactions with alpha 2-adrenoceptors. Prog Brain Res. 1986; 68:331-5. View PubMed Adler CH, Meller E, Goldstein M. Recovery of alpha 2-adrenoceptor binding and function after irreversible inactivation by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ). Eur J Pharmacol. 1985 Oct 8; 116(1-2):175-8. View PubMed Adler CH, Robin M, Adler MW. Tolerance to morphine-induced mydriasis in the rat pupil. Life Sci. 1981 Jun 1; 28(22):2469-75. View PubMed Adler C, Keren O, Korczyn AD. Tolerance to the Mydriatic effects of morphine in mice. J Neural Transm. 1980; 48(1):43-7. View PubMed Klemfuss H, Tallarida RJ, Adler CH, Adler MW. Morphine-induced mydriasis and fluctuation in the rat: time and dose relationships. Journal of Pharmacology & Experimental Therapeutics. 1979 Jan; 208(1):91-5. View PubMed Adler MW, Adler CH. Toxicity to heavy metals and relationship to seizure thresholds. Clin Pharmacol Ther. 1977 Nov; 22(5 Pt 2):774-9. View PubMed PST-20222097 主页 出版物