Whipple procedure

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Departments and specialties

Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery.

Departments with related expertise

Doctors who perform this procedure

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Research

Diagnostic radiologists

Doctors who specialize in diagnostic radiology research new ways of using advanced, high-resolution imaging, such as PET MRI, to care for people undergoing Whipple procedures.

Mayo Clinic surgeons developed a new protocol that makes Whipple surgery an option for more people and improves the survival among this group.

Because more people are living longer after Whipple procedures than in the past, Mayo Clinic researchers are examining how to improve quality of life after surgery.

In addition, in the Mayo Clinic Gastrointestinal Cancer Program, new diagnostic tools, treatments and approaches to prevention for pancreatic cancer are being studied. Mayo Clinic doctors in this program are dedicated to advancing scientific knowledge of cancers affecting the intestinal tract and to improving the quality of life of people affected by these diseases.

Publications

See a list of publications about pancreatic cancer by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Research Profiles

By Mayo Clinic Staff

Whipple procedure care at Mayo Clinic

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AboutCare at Mayo Clinic
June 14, 2024
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  1. Delaney CP. Pancreaticoduodenectomy. In: Netter's Surgical Anatomy and Approaches. 2nd ed. Elsevier; 2021. https://www.clinicalkey.com. Accessed March 24, 2023.
  2. Townsend CM Jr, et al. Exocrine pancreas. In: Sabiston Textbook of Surgery: The Biological Basis of Modern Surgical Practice. 21st ed. Elsevier; 2022. https://www.clinicalkey.com. Accessed March 24, 2023.
  3. Reber HA. Surgical resection of lesions of the head of the pancreas. https://www.uptodate.com/contents/search. Accessed March 24, 2023.
  4. Mantzavinou A, et al. Robotic versus open pancreaticoduodenectomy, comparing therapeutic indexes; a systematic review. International Journal of Surgery. 2022; doi:10.1016/j.ijsu.2022.106633.
  5. Simon R. Complications after pancreaticoduodenectomy. Surgical Clinics of North America. 2021; doi:10.1016/j.suc.2021.06.011.
  6. Riggin EA. Allscripts EPSi. Mayo Clinic. Feb. 9, 2017.
  7. Truty MJ (expert opinion). Mayo Clinic. Feb. 22, 2017.
  8. Fernandez-del Castillo C, et al. Overview of surgery in the treatment of exocrine pancreatic cancer and prognosis. https://www.uptodate.com/contents/search. Accessed March 24, 2023.
  9. Bergquist JR, et al. Implications of CA19-9 elevation for survival, staging and treatment sequencing in intrahepatic cholangiocarcinoma: A national cohort analysis. Journal of Surgical Oncology. 2016; doi:10.1002/jso.24381.
  10. Katz MHG, et al. Preoperative modified FOLFIRINOX treatment followed by Capecitabine-based chemoradiation for borderline resectable pancreatic cancer: Alliance for Clinical Trials in Oncology Trial A021101. JAMA Surgery. 2016; doi:10.1001/jamasurg.2016.
  11. Shubert CR, et al. Overall survival is increased among stage III pancreatic adenocarcinoma patients receiving neoadjuvant chemotherapy compared to surgery first and adjuvant chemotherapy: An intention to treat analysis of the National Cancer Database. Surgery. 2016; doi:10.1016/j.surg.2016.06.010.
  12. Bergquist JR, et al. Risk by indication for pancreaticoduodenectomy in patients 80 years and older: A study from the American College of Surgeons National Surgical Quality Improvement Program. HPB. 2016; doi:10.1016/j.hpb.2016.07.012.

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Whipple procedure